Multidirectional Yoga for Cognition

• ClinicalTrials.gov Identifier: NCT03799640
• Recruitment Status: Completed
• First Posted: January 10, 2019
• Last Update Posted: September 10, 2019
• Sponsor: University of Miami
• Information provided by (Responsible Party): Joseph Signorile, University of Miami

Study Description

Brief Summary:

Older individuals, 60-90, will be provided regular or cognitively based yoga training. They will then be evaluated using standard cognitive testing devices.

Condition or disease	Intervention/treatment	Phase
Standard Yoga; Multi-directional Yoga; Educational Control	Other: Standard Yoga; Other: Multi-directional Yoga; Other: Educational Control	Not Applicable

Detailed Description:

Reductions in executive function are common with age. Along with these declines come reductions in simple functional patterns of daily living such as crossing a street, walking in a crowded area, or performing any functions that occurs in an open (changing) environment. This study will use a newly developed yoga program incorporating multi-directional movements, cognitive challenges and visuomotor disturbances to improve executive function and associated movements in persons over 60 years of age.

Study Design

• Study Type: Interventional (Clinical Trial)
• Actual Enrollment: 40 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Intervention Model Description: Comparison of Yoga Interventions
• Masking: Single (Investigator)
• Masking Description: Tests will not be performed by the investigators providing the interventions..
• Primary Purpose: Treatment
• Official Title: Multidirectional Yoga Training to Improve in Healthy Older Participants
• Actual Study Start Date: December 5, 2018
• Actual Primary Completion Date: August 15, 2019
• Actual Study Completion Date: August 15, 2019

Arms and Interventions

Arm	Intervention/treatment
Experimental: Standard Yoga; Yoga will be performed using linear forward and backward movements.	Other: Multi-directional Yoga; The multidirectional yoga training program will use both simple and complex movement sequences (asana or postures) that include a cognitive component. For example, participants will be taught a movement sequence that includes 16-20 yoga postures that increase in difficulty as the training progresses.; Other: Educational Control; Lectures on health and fitness
Experimental: Multi-directional Yoga; The multidirectional yoga training program will use both simple and complex movement sequences (asana or postures) that include a cognitive component. For example, participants will be taught a movement sequence that includes 16-20 yoga postures that increase in difficulty as the training progresses. .	Other: Standard Yoga; Yoga using standard poses and linear movements; Other: Educational Control; Lectures on health and fitness
Experimental: Educational Control; Lectures on Health and Wellness	Other: Standard Yoga; Yoga using standard poses and linear movements; Other: Multi-directional Yoga; The multidirectional yoga training program will use both simple and complex movement sequences (asana or postures) that include a cognitive component. For example, participants will be taught a movement sequence that includes 16-20 yoga postures that increase in difficulty as the training progresses.

Outcome Measures

Primary Outcome Measures :

1. NIH Toolbox: Picture Sequence Memory Test [ Time Frame: 5 minutes ]
   Measures episodic memory. Participants are asked to reproduce a sequence of pictures that is shown on the screen.
2. NIH Toolbox Flanker test [ Time Frame: 5 minutes ]
   Measures attention and inhibitory control. Participant focuses on a given stimulus while inhibiting attention to stimuli flanking it.
3. NIH Toolbox List Sorting test [ Time Frame: 5 minutes ]
   Measures working memory. Participant recalls and sequences different visually and orally presented stimuli.
4. NIH Toolbox Pattern Comparison Processing Speed test [ Time Frame: 5 minutes ]
   Measures speed of processing. Participants discern whether two side-by-side pictures are the same or not, with 85 seconds to respond to as many items as possible. Items are simple so as to purely measure processing speed.
5. Walking Executive Function Tests [ Time Frame: 10 minutes ]
   Walking and responding to visual cues presented on a 60 inch monitor.
6. Timed up-and-go [ Time Frame: 5 minutes ]
   Rising from a chair, circumventing a cone and returning to the chair.

Eligibility Criteria

• Ages Eligible for Study: 60 Years to 90 Years (Adult, Older Adult)
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• 60-90 years of age
• Capable of walking 50 feet with or without a walking aid-

Exclusion Criteria:

• Regularly participating in yoga or other balance training program
• Currently participating in another exercise study
• Unable to commit to study duration
• Uncontrolled neuromuscular or cardiovascular disease that prevents participation in an exercise study
• Advised not to exercise by their physician

Contacts and Locations

Locations

United States, Florida

Max Orovitz Laboratories

Coral Gables, Florida, United States, 33146-2416

Laboratory of Neruomuscular Research and Active Aging

Coral Gables, Florida, United States, 33147

Sponsors and Collaborators

University of Miami

Investigators

• Principal Investigator: Joseph Signorile, PhD; University of Miami

More Information

• Responsible Party: Joseph Signorile, Professor, University of Miami
• ClinicalTrials.gov Identifier: NCT03799640
• Other Study ID Numbers: 20180704
• First Posted: January 10, 2019
• Last Update Posted: September 10, 2019
• Last Verified: September 2019

Individual Participant Data (IPD) Sharing Statement:

• Plan to Share IPD: No

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No