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Neuronal Correlates of Priming on Goal-directed and Cue-dependent Behavior

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ClinicalTrials.gov Identifier: NCT03735732
Recruitment Status : Recruiting
First Posted : November 8, 2018
Last Update Posted : November 12, 2020
Sponsor:
Information provided by (Responsible Party):
Sabine Frank, University Hospital Tuebingen

Study Description
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Brief Summary:
The current proposal aims to investigate neuronal correlates of implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior.

Condition or disease Intervention/treatment
Functional Magnetic Resonance Imaging Habits Eating Behavior Behavioral: prime

Detailed Description:
Food choice and intake is a daily and throughout normal subject. However, for more and more people eating habits and the question of food choice are of increasing interest and in several cases even a problem. The prevalence of obesity has tripled in the last decades and it is even spoken of an obesity epidemic. Life style interventions to lose weight often fail on the long run, also because people fall back into former unhealthy eating habits. Various factors influence our daily food choice, not all of which are apparent to ourselves. Thus, food choice might be goal-directed and therefore conscious and reflective, yet in other circumstances the choice to eat something specific might be based on cue dependent processes which are automatic and thus difficult to control. Since a change in eating-behavior and long-lasting weight loss is most problematic to achieve, the current proposal aims to investigate neuronal correlates of implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior.
Study Design
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Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Case-Control
Time Perspective: Cross-Sectional
Official Title: Neuronal Correlates of Priming on Goal-directed and Cue-dependent Behavior
Actual Study Start Date : February 1, 2019
Estimated Primary Completion Date : September 2021
Estimated Study Completion Date : December 2021
Groups and Cohorts
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Group/Cohort Intervention/treatment
weight status
mindset Behavioral: prime
groups be confronted with health or palatability aspects of food items


Outcome Measures
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Primary Outcome Measures :
  1. Change in neuronal correlates [ Time Frame: before and 5 minutes after visually presented food items ]
    Change of BOLD response measured by fMRI


Eligibility Criteria
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Ages Eligible for Study:   20 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
healthy lean and obese volunteers
Criteria

Inclusion Criteria:

  • experimental: participants with obesity
  • control: participants with normal-weight

Exclusion Criteria:

  • currently dieting
  • intolerance to provided food
  • cognitive impairment
  • contraindications for fMRI measurements
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03735732


Contacts
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Contact: Sabine Frank 004970712981193 s.frank@uni-tuebingen.de

Locations
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Germany
University of Tübingen Recruiting
Tübingen, Germany
Contact: Sabine Frank    004970712981193      
Sponsors and Collaborators
University Hospital Tuebingen
More Information
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Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
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Responsible Party: Sabine Frank, Research Associate, University Hospital Tuebingen
ClinicalTrials.gov Identifier: NCT03735732    
Other Study ID Numbers: PIT_brain
First Posted: November 8, 2018    Key Record Dates
Last Update Posted: November 12, 2020
Last Verified: November 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No