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Dipyridamole Induced Ischemia and Biomarkers

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ClinicalTrials.gov Identifier: NCT03688815
Recruitment Status : Completed
First Posted : September 28, 2018
Last Update Posted : September 28, 2018
Sponsor:
Information provided by (Responsible Party):
Tihamér Molnár, University of Pecs

Study Description
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Brief Summary:
Analysis of certain biomarkers and transient myocardial perfusion deficit revealed by myocardial perfusion scintigraphy.

Condition or disease Intervention/treatment
Ischemic Heart Disease Ischemic Attack Diagnostic Test: myocardial perfusion scintigraphy

Detailed Description:
The prospectively enrolled patients were followed up to 5 years. Adverse major events (MI, stroke, death) suffered during follow-up were retrospectively analysed.
Study Design
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Study Type : Observational
Actual Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Relationship Between the L-arginine Pathway Metabolites and Dipyridamole Stress Induced Transient Myocardial Ischaemia
Actual Study Start Date : January 1, 2009
Actual Primary Completion Date : January 1, 2010
Actual Study Completion Date : January 1, 2017

Resource links provided by the National Library of Medicine


Groups and Cohorts
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Group/Cohort Intervention/treatment
Patients with ischemic heart disease
Patients with ischemic heart disease scheduled for myocardial perfusion scintigraphy were enrolled. Biomarkers were analysed form periferal blood. Patients outcome data were followed up to 5 years.
 Diagnostic Test: myocardial perfusion scintigraphy
Myocardial perfusion scintigraphy as it is described in the international literature.


Outcome Measures
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Primary Outcome Measures :
  1. Myocardial perfusion abnormality [ Time Frame: 5 year follow-up after MPS ]
    Myocardial perfusion was quantified based on myocardial perfusion scintigraphy (MPS).


Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Consecutive patients with IHD were enrolled.
Criteria

Inclusion Criteria: 1. written informed consent. 2. clinical diagnosis of ischemic heart disease (IHD) -

Exclusion Criteria: 1. refused written informed consent. 2. lost data during follow-up

-

Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03688815


Locations
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Hungary
University of Pecs
Pécs, Baranya, Hungary, 7624
Sponsors and Collaborators
University of Pecs
Investigators
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Principal Investigator: Tihamer Molnar, MD University of Pecs
More Information
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Additional Information:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Tihamér Molnár, Associate professor, University of Pecs
ClinicalTrials.gov Identifier: NCT03688815    
Other Study ID Numbers: PTE3950
First Posted: September 28, 2018    Key Record Dates
Last Update Posted: September 28, 2018
Last Verified: September 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: IPD sharing plan: publication of data in a peer-reviewed journal

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Heart Diseases
Myocardial Ischemia
Coronary Artery Disease
Ischemia
Pathologic Processes
 Cardiovascular Diseases
Vascular Diseases
Coronary Disease
Arteriosclerosis
Arterial Occlusive Diseases