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Trial record 1 of 1 for:    A171601
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Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03633331
Recruitment Status : Recruiting
First Posted : August 16, 2018
Last Update Posted : June 20, 2019
Sponsor:
Collaborator:
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Alliance for Clinical Trials in Oncology

Brief Summary:
This phase II trial studies the side effects and how well palbociclib and letrozole or fulvestrant works in treating patients aged 70 years and older with estrogen receptor positive, HER2 negative breast cancer that has spread to other places in the body. Palbociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as letrozole or fulvestrant, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving palbociclib and letrozole or fulvestrant may work better in treating patients with breast cancer. The trial will explore factors other than chronologic age that can affect toxicity rates as identified using a cancer-specific geriatric assessment.

Condition or disease Intervention/treatment Phase
Estrogen Receptor-positive Breast Cancer HER2/Neu Negative Stage IV Breast Cancer AJCC v6 and v7 Drug: Palbociclib Drug: Letrozole Drug: Fulvestrant Other: Questionnaire Administration Other: Quality-of-Life Assessment Phase 2

Detailed Description:

PRIMARY OBJECTIVES:

I. To estimate the safety and tolerability (adverse event rate) of the combination of palbociclib and letrozole or fulvestrant in adults age 70 or older with estrogen receptor-positive, HER2-negative metastatic breast cancer.

SECONDARY OBJECTIVES:

I. To describe the full toxicity profile including all grade 2 and higher adverse events (per National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] version [v.] 5.0), specifically estimating the rate of grade 2 and higher myelosuppression (neutropenia, leukopenia, thrombocytopenia, and anemia), neutropenic fever, gastrointestinal (GI) side effects (nausea, diarrhea, decreased appetite, vomiting, mucositis-oral), fatigue, neuropathy, and thromboembolism.

II. To describe rates of dose reductions, dose holds, and hospitalizations. III. To estimate median time to treatment failure, including progression free survival and overall survival.

IV. To estimate the rate of adherence to palbociclib, letrozole and fulvestrant.

V. To explore factors other than chronologic age that can affect toxicity rates as identified using a cancer-specific geriatric assessment.

VI. To describe the results of the Overall Treatment Utility (OTU). VII. To determine the degree of agreement between patient-reported adverse events (AEs) using Patient Reported Outcomes (PRO)-CTCAE measures and those reported using traditional collections for AEs.

VIII. To examine the association between sarcopenia and the development of toxicity and adverse events.

OUTLINE:

Patients receive palbociclib orally (PO) once daily (QD) on days 1-21. Patients also receive letrozole PO QD on days 1-28 or fulvestrant intramuscularly (IM) on days 1 and 15 of course 1 and on day 1 of subsequent courses per Doctor of Medicine (MD) discretion. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up for up to 5 years.


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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 88 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A Phase II Trial Assessing the Tolerability of Palbociclib in Combination With Letrozole or Fulvestrant in Patients Aged 70 and Older With Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer
Actual Study Start Date : August 15, 2018
Estimated Primary Completion Date : September 2019
Estimated Study Completion Date : August 2024

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Breast Cancer

Arm Intervention/treatment
Experimental: Treatment (palbociclib, letrozole or fulvestrant)
Patients receive palbociclib PO QD on days 1-21. Patients also receive letrozole PO QD on days 1-28 or fulvestrant IM on days 1 and 15 of course 1 and on day 1 of subsequent courses per MD discretion. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Drug: Palbociclib
Given PO

Drug: Letrozole
Given PO

Drug: Fulvestrant
Given IM

Other: Questionnaire Administration
Ancillary studies

Other: Quality-of-Life Assessment
Ancillary studies




Primary Outcome Measures :
  1. Incidence of adverse events [ Time Frame: Up to 1 year ]
    Defined as the proportion of patients with documentation of grade 3 - 5 toxicity (regardless of attribution using the National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] version [v.] 5.0 criteria). A 95% binomial confidence interval for single proportions will be constructed for the severe toxicity rate during treatment. Univariate relationships between the primary endpoint and various pre-treatment patient characteristics such as anemia, self-assessed functional status, or social support will be described via cross-tabulation and Fisher's exact testing. Exploratory logistic regression modeling, with limited generalizability due to the modest sample size, will be used to assess the relative contributions of these variables impact the likelihood of developing a severe toxicity during treatment. The strength of this association will be expressed in terms of an odds ratio and its associated 95% confidence interval.


Secondary Outcome Measures :
  1. Incidence of drug toxicities - Measured by National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] v. 5.0 [ Time Frame: Up to 1 year ]
    Measured by National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] v. 5.0

  2. Dose reduction, dose hold, and hospitalization reasons [ Time Frame: Up to 1 year ]
    A 95% binomial confidence interval for single proportions will be constructed for the percentage of patients that had at least one dose reduction, dose hold, or hospitalization within the first year of treatment.

  3. Time to treatment failure (and reason for coming off study - toxicity, patient preference, progression) [ Time Frame: Up to 5 years ]
    Distributions time to treatment failure will be estimated using Kaplan-Meier methodology. Treatment failure is defined as a severe adverse event, disease progression or patient refusal to continue assigned treatment. Any reason that treatment is discontinued to time to treatment failure and not censor patients will be included. The reason for treatment discontinuation will be captured.

  4. Palbociclib adherence rate [ Time Frame: Up to 12 weeks ]
    Patients to be included in the analysis cohort will be those patients who have taken one or more doses of the study treatment. Those patients will be considered adherent to study treatment. For each of the first 3 cycles, an estimate of the proportion of patients who meet the criteria for adherence and its corresponding 95% confidence interval will be determined.

  5. Response rate as determined by Response Evaluation Criteria in Solid Tumors (RECIST) [ Time Frame: Up to 1 year ]
    The response rate is defined as the proportion of patients whose disease status met Response Evaluation Criteria in Solid Tumors (RECIST) criteria for complete response (CR) or partial response (PR) on 2 consecutive evaluations at least 8 weeks apart. A 95% binomial confidence interval for the response rate will be constructed.

  6. Progression free survival (PFS) [ Time Frame: From start of treatment to the first of the following disease events: local/regional/distant recurrence, invasive contralateral breast disease, second primary or death due to any cause, assessed up to 5 years ]
    Distributions of progression free survival (PFS) times will be estimated using Kaplan-Meier methodology.

  7. Overall survival (OS) [ Time Frame: Up to 5 years ]
    Distributions of overall survival (OS) times will be estimated using Kaplan-Meier methodology.

  8. Overall Treatment Utility (OTU) results [ Time Frame: Up to 1 year ]
    OTU is a novel composite endpoint developed by investigators of the FOCUS2 trial to assess the outcome of palliative chemotherapy. The patient will be given either an overall score of "good", "intermediate", or "poor". A 95% binomial confidence interval will be constructed for the percentage of patients that scored "good" on the OTU.

  9. Sarcopenia analysis [ Time Frame: Up to 1 year ]
    Will examine variables associated with skeletal muscle loss during treatment and whether skeletal muscle loss during treatment is associated with the presence of grade 3-5 toxicity and adverse events. Sarcopenia will be treated as a binary variable using the Skeletal Muscle Index (SMI) (SMI < 41 cm^2/m^2 vs. SMI > 41 cm^2/m^2) and differences in grades chemotherapy toxicity and adverse events will be analyzed using two group t-tests and fisher's exact test. The number of patients with and without sarcopenia grouped by patients with or without grade 3+ Adverse Events (AE's) will be also be reported.

  10. Quality of life as measured by the European Quality of Life Five Dimension Three Level Questionnaire (EQ-5D-3L) [ Time Frame: Up to 1 year ]
    European Quality of Life Five Dimension Three Level Questionnaire (EQ-5D-3L) is comprised of 5 dimensions. Mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Each dimension has 3 levels, no problems, some problems, extreme problems. The EQ-5D-3L can be converted to a single summary index. The median and range of this total score will be reported.



Information from the National Library of Medicine

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Ages Eligible for Study:   70 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Documentation of disease: estrogen receptor positive, HER2 negative metastatic breast cancer; histologic confirmation is required
  • Measurable disease or non-measurable disease
  • Planning to begin endocrine therapy for metastatic disease; one prior line of endocrine therapy or chemotherapy for metastatic disease is allowed
  • No prior therapy with a CDK inhibitor
  • Resolution of all acute toxic effects of prior therapy or surgical procedures to CTCAE grade =< 1 (except alopecia) prior to registration
  • No untreated brain metastases; patients with treated brain metastases must have completed treatment with steroids to be eligible
  • No second malignancies other than non-melanoma skin cancers or cervical carcinoma in situ
  • No active infection requiring treatment with antibiotics
  • Patients must be able to swallow and retain oral medication
  • Patients must be able to read and comprehend English or Spanish
  • Absolute neutrophil count (ANC) >= 1500/mm^3 (1.5 x 10^9/L)
  • Platelet count >= 100,000/mm^3 (100 x 10^9/L)
  • Creatinine clearance >= 30 ml/min calculated using the Cockcroft-Gault formula
  • Total serum bilirubin =< 1.5 upper limit of normal (ULN) (< 3 ULN if Gilbert's disease)
  • Aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) =< 3 x ULN (=< 5.0 x ULN if liver metastases present)
  • Alkaline phosphatase =< 2.5 x ULN (=< 5 x ULN if bone or liver metastases present)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03633331


Contacts
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Contact: Mina Sedrak, MD, MS 626-218-4173 msedrak@coh.org

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Locations
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United States, Alaska
Anchorage Associates in Radiation Medicine Recruiting
Anchorage, Alaska, United States, 98508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Anchorage Radiation Therapy Center Recruiting
Anchorage, Alaska, United States, 99504
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Alaska Breast Care and Surgery LLC Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Alaska Oncology and Hematology LLC Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Alaska Women's Cancer Care Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
Anchorage Oncology Centre Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Katmai Oncology Group Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Alaska Medical Center Recruiting
Anchorage, Alaska, United States, 99508
Contact: Site Public Contact    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
United States, California
PCR Oncology Recruiting
Arroyo Grande, California, United States, 93420
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Providence Saint Joseph Medical Center/Disney Family Cancer Center Recruiting
Burbank, California, United States, 91505
Contact: Site Public Contact    818-847-4793    Najee.Boucher@providence.org   
Principal Investigator: Alison K. Conlin         
City of Hope Corona Recruiting
Corona, California, United States, 92879
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope Comprehensive Cancer Center Recruiting
Duarte, California, United States, 91010
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope Antelope Valley Recruiting
Lancaster, California, United States, 93534
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope Mission Hills Recruiting
Mission Hills, California, United States, 91345
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope Rancho Cucamonga Recruiting
Rancho Cucamonga, California, United States, 91730
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope - Santa Clarita Recruiting
Santa Clarita, California, United States, 91355
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope South Pasadena Recruiting
South Pasadena, California, United States, 91030
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
City of Hope West Covina Recruiting
West Covina, California, United States, 91790
Contact: Site Public Contact    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Mina S. Sedrak         
United States, Colorado
SCL Health Saint Joseph Hospital Recruiting
Denver, Colorado, United States, 80218
Contact: Site Public Contact    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Good Samaritan Medical Center Recruiting
Lafayette, Colorado, United States, 80026
Contact: Site Public Contact    303-673-1622      
Principal Investigator: Keren Sturtz         
SCL Health Lutheran Medical Center Recruiting
Wheat Ridge, Colorado, United States, 80033
Contact: Site Public Contact    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
United States, Delaware
Beebe Medical Center Recruiting
Lewes, Delaware, United States, 19958
Contact: Site Public Contact    302-645-3770    Dmiskin@Beebehealthcare.org   
Principal Investigator: Gregory A. Masters         
Delaware Clinical and Laboratory Physicians PA Recruiting
Newark, Delaware, United States, 19713
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
Helen F Graham Cancer Center Recruiting
Newark, Delaware, United States, 19713
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
Medical Oncology Hematology Consultants PA Recruiting
Newark, Delaware, United States, 19713
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
Regional Hematology and Oncology PA Suspended
Newark, Delaware, United States, 19713
Christiana Care Health System-Christiana Hospital Recruiting
Newark, Delaware, United States, 19718
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
Beebe Health Campus Recruiting
Rehoboth Beach, Delaware, United States, 19971
Contact: Site Public Contact    302-645-3100    Dmiskin@Beebehealthcare.org   
Principal Investigator: Gregory A. Masters         
Nanticoke Memorial Hospital Recruiting
Seaford, Delaware, United States, 19973
Contact: Site Public Contact    302-645-3100    Dmiskin@Beebehealthcare.org   
Principal Investigator: Gregory A. Masters         
Christiana Care Health System-Wilmington Hospital Recruiting
Wilmington, Delaware, United States, 19801
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
United States, District of Columbia
Sibley Memorial Hospital Recruiting
Washington, District of Columbia, United States, 20016
Contact: Site Public Contact    202-243-2373    jquiver1@jhmi.edu   
Principal Investigator: Vered Stearns         
United States, Hawaii
Hawaii Cancer Care - Savio Recruiting
'Aiea, Hawaii, United States, 96701
Contact: Site Public Contact    808-539-2273      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Oncology Inc-Pali Momi Recruiting
'Aiea, Hawaii, United States, 96701
Contact: Site Public Contact    808-487-7447      
Principal Investigator: Jeffrey L. Berenberg         
Pali Momi Medical Center Recruiting
'Aiea, Hawaii, United States, 96701
Contact: Site Public Contact    808-486-6000      
Principal Investigator: Jeffrey L. Berenberg         
The Cancer Center of Hawaii-Pali Momi Recruiting
'Aiea, Hawaii, United States, 96701
Contact: Site Public Contact    808-678-9000      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Cancer Care Inc-POB II Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    808-524-6115      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Oncology Inc-POB I Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    808-532-0315      
Principal Investigator: Jeffrey L. Berenberg         
Island Urology Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    808-536-2306    virginia@cc.hawaii.edu   
Principal Investigator: Jeffrey L. Berenberg         
Queen's Medical Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Jeffrey L. Berenberg         
Straub Clinic and Hospital Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    808-522-4333      
Principal Investigator: Jeffrey L. Berenberg         
University of Hawaii Cancer Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Site Public Contact    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Cancer Care Inc-Liliha Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Site Public Contact    808-536-4888      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Oncology Inc-Kuakini Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Site Public Contact    808-531-8521      
Principal Investigator: Jeffrey L. Berenberg         
Kuakini Medical Center Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Site Public Contact    808-547-9816      
Principal Investigator: Jeffrey L. Berenberg         
The Cancer Center of Hawaii-Liliha Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Site Public Contact    808-547-6881      
Principal Investigator: Jeffrey L. Berenberg         
Kapiolani Medical Center for Women and Children Recruiting
Honolulu, Hawaii, United States, 96826
Contact: Site Public Contact    808-983-6090      
Principal Investigator: Jeffrey L. Berenberg         
Wilcox Memorial Hospital and Kauai Medical Clinic Recruiting
Lihue, Hawaii, United States, 96766
Contact: Site Public Contact    808-535-7960      
Principal Investigator: Jeffrey L. Berenberg         
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Recruiting
Boise, Idaho, United States, 83706
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Saint Luke's Mountain States Tumor Institute Recruiting
Boise, Idaho, United States, 83712
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
Saint Alphonsus Cancer Care Center-Caldwell Recruiting
Caldwell, Idaho, United States, 83605
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Walter Knox Memorial Hospital Recruiting
Emmett, Idaho, United States, 83617
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Saint Luke's Mountain States Tumor Institute - Fruitland Recruiting
Fruitland, Idaho, United States, 83619
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
Idaho Urologic Institute-Meridian Recruiting
Meridian, Idaho, United States, 83642
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Saint Luke's Mountain States Tumor Institute - Meridian Recruiting
Meridian, Idaho, United States, 83642
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
Saint Alphonsus Medical Center-Nampa Recruiting
Nampa, Idaho, United States, 83686
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Saint Luke's Mountain States Tumor Institute - Nampa Recruiting
Nampa, Idaho, United States, 83686
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
Saint Luke's Mountain States Tumor Institute-Twin Falls Recruiting
Twin Falls, Idaho, United States, 83301
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Alison K. Conlin         
United States, Illinois
Rush - Copley Medical Center Recruiting
Aurora, Illinois, United States, 60504
Contact: Site Public Contact    630-978-6212    Cancer.Research@rushcopley.com   
Principal Investigator: Pratima Chalasani         
Illinois CancerCare-Bloomington Recruiting
Bloomington, Illinois, United States, 61704
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Canton Recruiting
Canton, Illinois, United States, 61520
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Carthage Recruiting
Carthage, Illinois, United States, 62321
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Centralia Oncology Clinic Recruiting
Centralia, Illinois, United States, 62801
Contact: Site Public Contact    217-876-4740    rhamrick@dmhhs.org   
Principal Investigator: Bryan A. Faller         
Northwestern University Recruiting
Chicago, Illinois, United States, 60611
Contact: Site Public Contact    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Ami N. Shah         
University of Chicago Comprehensive Cancer Center Recruiting
Chicago, Illinois, United States, 60637
Contact: Site Public Contact    773-702-8222    cancerclinicaltrials@bsd.uchicago.edu   
Principal Investigator: Olwen M. Hahn         
Carle on Vermilion Recruiting
Danville, Illinois, United States, 61832
Contact: Site Public Contact    800-446-5532    Research@carle.com   
Principal Investigator: Pratima Chalasani         
Cancer Care Specialists of Illinois - Decatur Recruiting
Decatur, Illinois, United States, 62526
Contact: Site Public Contact    217-876-4740      
Principal Investigator: Bryan A. Faller         
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: Site Public Contact    217-876-4740    rhamrick@dmhhs.org   
Principal Investigator: Bryan A. Faller         
Carle Physician Group-Effingham Recruiting
Effingham, Illinois, United States, 62401
Contact: Site Public Contact    800-446-5532    Research@carle.com   
Principal Investigator: Pratima Chalasani         
Crossroads Cancer Center Recruiting
Effingham, Illinois, United States, 62401
Contact: Site Public Contact    217-876-4740    rhamrick@dmhhs.org   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Eureka Recruiting
Eureka, Illinois, United States, 61530
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Galesburg Recruiting
Galesburg, Illinois, United States, 61401
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Western Illinois Cancer Treatment Center Recruiting
Galesburg, Illinois, United States, 61401
Contact: Site Public Contact    309-344-2831      
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Kewanee Clinic Recruiting
Kewanee, Illinois, United States, 61443
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Macomb Recruiting
Macomb, Illinois, United States, 61455
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Carle Physician Group-Mattoon/Charleston Recruiting
Mattoon, Illinois, United States, 61938
Contact: Site Public Contact    800-446-5532    Research@carle.com   
Principal Investigator: Pratima Chalasani         
Good Samaritan Regional Health Center Recruiting
Mount Vernon, Illinois, United States, 62864
Contact: Site Public Contact    618-242-4600      
Principal Investigator: Jay W. Carlson         
Illinois CancerCare-Ottawa Clinic Recruiting
Ottawa, Illinois, United States, 61350
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Pekin Recruiting
Pekin, Illinois, United States, 61554
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Methodist Medical Center of Illinois Recruiting
Peoria, Illinois, United States, 61636
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Peru Recruiting
Peru, Illinois, United States, 61354
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Valley Radiation Oncology Recruiting
Peru, Illinois, United States, 61354
Contact: Site Public Contact    815-664-4141      
Principal Investigator: Bryan A. Faller         
Illinois CancerCare-Princeton Recruiting
Princeton, Illinois, United States, 61356
Contact: Site Public Contact    309-243-3605    andersonj@illinoiscancercare.com   
Principal Investigator: Bryan A. Faller         
Southern Illinois University School of Medicine Recruiting
Springfield, Illinois, United States, 62702
Contact: Site Public Contact    217-545-7929      
Principal Investigator: Bryan A. Faller         
Springfield Clinic Recruiting
Springfield, Illinois, United States, 62702
Contact: Site Public Contact    800-444-7541      
Principal Investigator: Bryan A. Faller         
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781
Contact: Site Public Contact    217-788-3528      
Principal Investigator: Bryan A. Faller         
Cancer Care Specialists of Illinois-Swansea Recruiting
Swansea, Illinois, United States, 62226
Contact: Site Public Contact    217-876-4740    rhamrick@dmhhs.org   
Principal Investigator: Bryan A. Faller         
Carle Cancer Center Recruiting
Urbana, Illinois, United States, 61801
Contact: Site Public Contact    800-446-5532    Research@carle.com   
Principal Investigator: Pratima Chalasani         
The Carle Foundation Hospital Recruiting
Urbana, Illinois, United States, 61801
Contact: Site Public Contact    800-446-5532    Research@carle.com   
Principal Investigator: Pratima Chalasani         
Rush-Copley Healthcare Center Recruiting
Yorkville, Illinois, United States, 60560
Contact: Site Public Contact    630-978-6212    Cancer.Research@rushcopley.com   
Principal Investigator: Pratima Chalasani         
United States, Iowa
Mary Greeley Medical Center Recruiting
Ames, Iowa, United States, 50010
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
McFarland Clinic PC - Ames Recruiting
Ames, Iowa, United States, 50010
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
McFarland Clinic PC-Boone Recruiting
Boone, Iowa, United States, 50036
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
Physicians' Clinic of Iowa PC Recruiting
Cedar Rapids, Iowa, United States, 52402
Contact: Site Public Contact    319-297-2900    cetscheidt@pcofiowa.com   
Principal Investigator: William P. Fusselman         
Mercy Hospital Recruiting
Cedar Rapids, Iowa, United States, 52403
Contact: Site Public Contact    319-365-4673      
Principal Investigator: Deborah W. Wilbur         
Oncology Associates at Mercy Medical Center Recruiting
Cedar Rapids, Iowa, United States, 52403
Contact: Site Public Contact    319-363-2690      
Principal Investigator: Deborah W. Wilbur         
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Site Public Contact    515-241-6727      
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Des Moines Recruiting
Des Moines, Iowa, United States, 50309
Contact: Site Public Contact    515-282-2921      
Principal Investigator: Robert J. Behrens         
Broadlawns Medical Center Recruiting
Des Moines, Iowa, United States, 50314
Contact: Site Public Contact    515-282-2200      
Principal Investigator: Robert J. Behrens         
Iowa Lutheran Hospital Recruiting
Des Moines, Iowa, United States, 50316
Contact: Site Public Contact    515-241-8704      
Principal Investigator: Robert J. Behrens         
McFarland Clinic PC-Trinity Cancer Center Recruiting
Fort Dodge, Iowa, United States, 50501
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
Trinity Regional Medical Center Recruiting
Fort Dodge, Iowa, United States, 50501
Contact: Site Public Contact    515-574-8302      
Principal Investigator: Robert J. Behrens         
McFarland Clinic PC-Jefferson Recruiting
Jefferson, Iowa, United States, 50129
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
McFarland Clinic PC-Marshalltown Recruiting
Marshalltown, Iowa, United States, 50158
Contact: Site Public Contact    515-956-4132      
Principal Investigator: Debra M. Prow         
Siouxland Regional Cancer Center Recruiting
Sioux City, Iowa, United States, 51101
Contact: Site Public Contact    712-252-9326    HoopingarnerT@jencc.com   
Principal Investigator: Donald B. Wender         
Methodist West Hospital Recruiting
West Des Moines, Iowa, United States, 50266-7700
Contact: Site Public Contact    515-343-1000      
Principal Investigator: Robert J. Behrens         
United States, Kansas
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Site Public Contact    316-268-5374    Keisha.humphries@ascension.org   
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Wichita Medical Arts Tower Recruiting
Wichita, Kansas, United States, 67208
Contact: Site Public Contact    316-268-5374    Keisha.humphries@ascension.org   
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Wichita Recruiting
Wichita, Kansas, United States, 67214
Contact: Site Public Contact    316-268-5374    Keisha.humphries@ascension.org   
Principal Investigator: Shaker R. Dakhil         
United States, Louisiana
Ochsner Medical Center Jefferson Recruiting
New Orleans, Louisiana, United States, 70121
Contact: Site Public Contact    504-703-8712    Gregory.Johnstone@ochsner.org   
Principal Investigator: John T. Cole         
United States, Maine
Eastern Maine Medical Center Recruiting
Bangor, Maine, United States, 04401
Contact: Site Public Contact    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Lafayette Family Cancer Center-EMMC Recruiting
Brewer, Maine, United States, 04412
Contact: Site Public Contact    800-987-3005      
Principal Investigator: Thomas H. Openshaw         
United States, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting
Baltimore, Maryland, United States, 21287
Contact: Site Public Contact    410-955-8804    jhcccro@jhmi.edu   
Principal Investigator: Vered Stearns         
Walter Reed National Military Medical Center Recruiting
Bethesda, Maryland, United States, 20889-5600
Contact: Site Public Contact    301-319-2100      
Principal Investigator: Karen G. Zeman         
United States, Massachusetts
Brigham and Women's Hospital Recruiting
Boston, Massachusetts, United States, 02115
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Rachel A. Freedman         
Dana-Farber Cancer Institute Recruiting
Boston, Massachusetts, United States, 02215
Contact: Site Public Contact    877-442-3324      
Principal Investigator: Rachel A. Freedman         
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Recruiting
Milford, Massachusetts, United States, 01757
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Rachel A. Freedman         
Dana-Farber/Brigham and Women's Cancer Center at South Shore Recruiting
South Weymouth, Massachusetts, United States, 02190
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Rachel A. Freedman         
United States, Michigan
Hickman Cancer Center Recruiting
Adrian, Michigan, United States, 49221
Contact: Site Public Contact    517-265-0116      
Principal Investigator: Rex B. Mowat         
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
IHA Hematology Oncology Consultants-Brighton Recruiting
Brighton, Michigan, United States, 48114
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Joseph Mercy Brighton Recruiting
Brighton, Michigan, United States, 48114
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
IHA Hematology Oncology Consultants-Canton Recruiting
Canton, Michigan, United States, 48188
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Joseph Mercy Canton Recruiting
Canton, Michigan, United States, 48188
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Caro Cancer Center Recruiting
Caro, Michigan, United States, 48723
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
IHA Hematology Oncology Consultants-Chelsea Recruiting
Chelsea, Michigan, United States, 48118
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Joseph Mercy Chelsea Recruiting
Chelsea, Michigan, United States, 48118
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Ascension Saint John Hospital Recruiting
Detroit, Michigan, United States, 48236
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Great Lakes Cancer Management Specialists-Doctors Park Recruiting
East China Township, Michigan, United States, 48054
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Genesee Cancer and Blood Disease Treatment Center Recruiting
Flint, Michigan, United States, 48503
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Genesee Hematology Oncology PC Recruiting
Flint, Michigan, United States, 48503
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48503
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Academic Hematology Oncology Specialists Recruiting
Grosse Pointe Woods, Michigan, United States, 48236
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center Recruiting
Grosse Pointe Woods, Michigan, United States, 48236
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Michigan Breast Specialists-Grosse Pointe Woods Recruiting
Grosse Pointe Woods, Michigan, United States, 48236
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Bronson Methodist Hospital Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Site Public Contact    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Site Public Contact    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Borgess Medical Center Recruiting
Kalamazoo, Michigan, United States, 49048
Contact: Site Public Contact    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Hope Cancer Clinic Recruiting
Livonia, Michigan, United States, 48154
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Great Lakes Cancer Management Specialists-Macomb Medical Campus Recruiting
Macomb, Michigan, United States, 48044
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Michigan Breast Specialists-Macomb Township Recruiting
Macomb, Michigan, United States, 48044
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Mary's Oncology/Hematology Associates of Marlette Recruiting
Marlette, Michigan, United States, 48453
Contact: Site Public Contact    989-343-2487      
Principal Investigator: Elie G. Dib         
Toledo Clinic Cancer Centers-Monroe Recruiting
Monroe, Michigan, United States, 48162
Contact: Site Public Contact    800-444-3561      
Principal Investigator: Rex B. Mowat         
Great Lakes Cancer Management Specialists-Rochester Hills Recruiting
Rochester Hills, Michigan, United States, 48309
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Ascension Saint Mary's Hospital Recruiting
Saginaw, Michigan, United States, 48601
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Elie G. Dib         
Oncology Hematology Associates of Saginaw Valley PC Recruiting
Saginaw, Michigan, United States, 48604
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Bhadresh Nayak MD PC-Sterling Heights Recruiting
Sterling Heights, Michigan, United States, 48312
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Ascension Saint Joseph Hospital Recruiting
Tawas City, Michigan, United States, 48764
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Advanced Breast Care Center PLLC Recruiting
Warren, Michigan, United States, 48088
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Great Lakes Cancer Management Specialists-Macomb Professional Building Recruiting
Warren, Michigan, United States, 48093
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Macomb Hematology Oncology PC Recruiting
Warren, Michigan, United States, 48093
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Michigan Breast Specialists-Warren Recruiting
Warren, Michigan, United States, 48093
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Saint Mary's Oncology/Hematology Associates of West Branch Recruiting
West Branch, Michigan, United States, 48661
Contact: Site Public Contact    989-343-2487      
Principal Investigator: Elie G. Dib         
Huron Gastroenterology PC Recruiting
Ypsilanti, Michigan, United States, 48106
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
IHA Hematology Oncology Consultants-Ann Arbor Recruiting
Ypsilanti, Michigan, United States, 48197
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
United States, Minnesota
Sanford Joe Lueken Cancer Center Recruiting
Bemidji, Minnesota, United States, 56601
Contact: Site Public Contact    218-333-5000    OncologyClinicalTrialsFargo@sanfordhealth.org   
Principal Investigator: Preston D. Steen         
Essentia Health Saint Joseph's Medical Center Recruiting
Brainerd, Minnesota, United States, 56401
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Bret E. Friday         
Fairview Ridges Hospital Recruiting
Burnsville, Minnesota, United States, 55337
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Essentia Health - Deer River Clinic Recruiting
Deer River, Minnesota, United States, 56636
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Essentia Health Saint Mary's - Detroit Lakes Clinic Recruiting
Detroit Lakes, Minnesota, United States, 56501
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Bret E. Friday         
Essentia Health Cancer Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Essentia Health Saint Mary's Medical Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Site Public Contact    888-203-7267      
Principal Investigator: Bret E. Friday         
Miller-Dwan Hospital Recruiting
Duluth, Minnesota, United States, 55805
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Fairview-Southdale Hospital Recruiting
Edina, Minnesota, United States, 55435
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Lake Region Healthcare Corporation-Cancer Care Recruiting
Fergus Falls, Minnesota, United States, 56537
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Essentia Health - Fosston Recruiting
Fosston, Minnesota, United States, 56542
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Unity Hospital Recruiting
Fridley, Minnesota, United States, 55432
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Essentia Health Hibbing Clinic Recruiting
Hibbing, Minnesota, United States, 55746
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Fairview Maple Grove Medical Center Recruiting
Maple Grove, Minnesota, United States, 55369
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Minnesota Oncology Hematology PA-Maplewood Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Saint John's Hospital - Healtheast Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Daniel M. Anderson         
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Health Partners Inc Recruiting
Minneapolis, Minnesota, United States, 55454
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Monticello Cancer Center Recruiting
Monticello, Minnesota, United States, 55362
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
New Ulm Medical Center Recruiting
New Ulm, Minnesota, United States, 56073
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Essentia Health - Park Rapids Recruiting
Park Rapids, Minnesota, United States, 56470
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
North Memorial Medical Health Center Recruiting
Robbinsdale, Minnesota, United States, 55422
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Park Nicollet Clinic - Saint Louis Park Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Essentia Health Sandstone Recruiting
Sandstone, Minnesota, United States, 55072
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Saint Francis Regional Medical Center Recruiting
Shakopee, Minnesota, United States, 55379
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Lakeview Hospital Recruiting
Stillwater, Minnesota, United States, 55082
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Sanford Thief River Falls Medical Center Recruiting
Thief River Falls, Minnesota, United States, 56701
Contact: Site Public Contact    605-312-3320      
Principal Investigator: Preston D. Steen         
Essentia Health Virginia Clinic Recruiting
Virginia, Minnesota, United States, 55792
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Ridgeview Medical Center Recruiting
Waconia, Minnesota, United States, 55387
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Minnesota Oncology Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Sanford Cancer Center Worthington Recruiting
Worthington, Minnesota, United States, 56187
Contact: Site Public Contact    605-312-3320      
Principal Investigator: Preston D. Steen         
Fairview Lakes Medical Center Recruiting
Wyoming, Minnesota, United States, 55092
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
United States, Missouri
Saint Louis Cancer and Breast Institute-Ballwin Recruiting
Ballwin, Missouri, United States, 63011
Contact: Site Public Contact    314-251-7058      
Principal Investigator: Jay W. Carlson         
Parkland Health Center-Bonne Terre Recruiting
Bonne Terre, Missouri, United States, 63628
Contact: Site Public Contact    314-996-5569      
Principal Investigator: Bryan A. Faller         
Saint Francis Medical Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: Site Public Contact    573-334-2230    sfmc@sfmc.net   
Principal Investigator: Bryan A. Faller         
University of Missouri - Ellis Fischel Recruiting
Columbia, Missouri, United States, 65212
Contact: Site Public Contact    573-882-7440      
Principal Investigator: Puja Nistala         
Siteman Cancer Center at West County Hospital Recruiting
Creve Coeur, Missouri, United States, 63141
Contact: Site Public Contact    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Lindsay L. Peterson         
Saint Louis Cancer and Breast Institute-South City Recruiting
Saint Louis, Missouri, United States, 63109
Contact: Site Public Contact    314-353-1870      
Principal Investigator: Jay W. Carlson         
Washington University School of Medicine Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Site Public Contact    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Lindsay L. Peterson         
Mercy Hospital South Recruiting
Saint Louis, Missouri, United States, 63128
Contact: Site Public Contact    314-525-4928      
Principal Investigator: Jay W. Carlson         
Siteman Cancer Center-South County Recruiting
Saint Louis, Missouri, United States, 63129
Contact: Site Public Contact    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Lindsay L. Peterson         
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: Site Public Contact    314-996-5569      
Principal Investigator: Bryan A. Faller         
Siteman Cancer Center at Christian Hospital Recruiting
Saint Louis, Missouri, United States, 63136
Contact: Site Public Contact    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Lindsay L. Peterson         
Mercy Hospital Saint Louis Recruiting
Saint Louis, Missouri, United States, 63141
Contact: Site Public Contact    314-251-7066      
Principal Investigator: Jay W. Carlson         
Siteman Cancer Center at Saint Peters Hospital Recruiting
Saint Peters, Missouri, United States, 63376
Contact: Site Public Contact    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Lindsay L. Peterson         
Sainte Genevieve County Memorial Hospital Recruiting
Sainte Genevieve, Missouri, United States, 63670
Contact: Site Public Contact    314-996-5569      
Principal Investigator: Bryan A. Faller         
Missouri Baptist Sullivan Hospital Recruiting
Sullivan, Missouri, United States, 63080
Contact: Site Public Contact    314-996-5569      
Principal Investigator: Bryan A. Faller         
Missouri Baptist Outpatient Center-Sunset Hills Recruiting
Sunset Hills, Missouri, United States, 63127
Contact: Site Public Contact    314-996-5569      
Principal Investigator: Bryan A. Faller         
United States, Montana
Community Hospital of Anaconda Recruiting
Anaconda, Montana, United States, 59711
Contact: Site Public Contact    406-969-6060    mccinfo@mtcancer.org   
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Site Public Contact    406-969-6060    mccinfo@mtcancer.org   
Principal Investigator: Benjamin T. Marchello         
Saint Patrick Hospital - Community Hospital Recruiting
Missoula, Montana, United States, 59802
Contact: Site Public Contact    406-327-3118    amy.hanneman@providence.org   
Principal Investigator: Alison K. Conlin         
United States, Nebraska
Nebraska Methodist Hospital Recruiting
Omaha, Nebraska, United States, 68114
Contact: Site Public Contact    402-354-5144      
Principal Investigator: Kirsten M. Leu         
United States, Nevada
Comprehensive Cancer Centers of Nevada - Henderson Recruiting
Henderson, Nevada, United States, 89052
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada-Horizon Ridge Recruiting
Henderson, Nevada, United States, 89052
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Las Vegas Cancer Center-Henderson Recruiting
Henderson, Nevada, United States, 89052
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
OptumCare Cancer Care at Seven Hills Recruiting
Henderson, Nevada, United States, 89052
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada-Southeast Henderson Recruiting
Henderson, Nevada, United States, 89074
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Desert West Surgery Recruiting
Las Vegas, Nevada, United States, 89102
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
University Medical Center of Southern Nevada Recruiting
Las Vegas, Nevada, United States, 89102
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Hope Cancer Care of Nevada Recruiting
Las Vegas, Nevada, United States, 89103
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
OptumCare Cancer Care at Oakey Recruiting
Las Vegas, Nevada, United States, 89106
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Radiation Oncology Centers of Nevada Central Recruiting
Las Vegas, Nevada, United States, 89106
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Radiation Oncology Centers of Nevada Southeast Recruiting
Las Vegas, Nevada, United States, 89119
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada - Northwest Recruiting
Las Vegas, Nevada, United States, 89128
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
OptumCare Cancer Care at MountainView Recruiting
Las Vegas, Nevada, United States, 89128
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada - Town Center Recruiting
Las Vegas, Nevada, United States, 89144
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada-Summerlin Recruiting
Las Vegas, Nevada, United States, 89144
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Las Vegas Cancer Center-Medical Center Recruiting
Las Vegas, Nevada, United States, 89148-2405
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada Recruiting
Las Vegas, Nevada, United States, 89148
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
OptumCare Cancer Care at Fort Apache Recruiting
Las Vegas, Nevada, United States, 89148
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Comprehensive Cancer Centers of Nevada - Central Valley Recruiting
Las Vegas, Nevada, United States, 89169
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Hope Cancer Care of Nevada-Pahrump Recruiting
Pahrump, Nevada, United States, 89048
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Renown Regional Medical Center Recruiting
Reno, Nevada, United States, 89502
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
Radiation Oncology Associates Recruiting
Reno, Nevada, United States, 89509
Contact: Site Public Contact    702-384-0013    research@sncrf.org   
Principal Investigator: John A. Ellerton         
United States, New Hampshire
New Hampshire Oncology Hematology PA-Concord Recruiting
Concord, New Hampshire, United States, 03301
Contact: Site Public Contact    603-224-2556      
Principal Investigator: Douglas J. Weckstein         
New Hampshire Oncology Hematology PA-Hooksett Recruiting
Hooksett, New Hampshire, United States, 03106
Contact: Site Public Contact    800-339-6484      
Principal Investigator: Douglas J. Weckstein         
The Dana-Farber Cancer Institute at Londonderry Recruiting
Londonderry, New Hampshire, United States, 03053
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Rachel A. Freedman         
United States, New Mexico
Lovelace Medical Center-Saint Joseph Square Recruiting
Albuquerque, New Mexico, United States, 87102
Contact: Site Public Contact    505-272-0530    AYost@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
University of New Mexico Cancer Center Recruiting
Albuquerque, New Mexico, United States, 87102
Contact: Site Public Contact    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Presbyterian Kaseman Hospital Recruiting
Albuquerque, New Mexico, United States, 87110
Contact: Site Public Contact    505-559-6113    WBurman@phs.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Presbyterian Rust Medical Center/Jorgensen Cancer Center Recruiting
Rio Rancho, New Mexico, United States, 87124
Contact: Site Public Contact    505-559-6113    WBurman@phs.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Christus Saint Vincent Regional Cancer Center Recruiting
Santa Fe, New Mexico, United States, 87505
Contact: Site Public Contact    505-913-8933    Olivia.Sloan@nmcancercare.com   
Principal Investigator: Ursa A. Brown-Glaberman         
United States, New York
Hematology Oncology Associates of Central New York-Auburn Recruiting
Auburn, New York, United States, 13021
Contact: Site Public Contact    315-472-7504      
Principal Investigator: Jeffrey J. Kirshner         
Northwell Health Imbert Cancer Center Recruiting
Bay Shore, New York, United States, 11706
Contact: Site Public Contact    516-734-8896      
Principal Investigator: Kit L. Cheng         
Montefiore Medical Center-Einstein Campus Suspended
Bronx, New York, United States, 10461
Montefiore Medical Center-Weiler Hospital Suspended
Bronx, New York, United States, 10461
Montefiore Medical Center - Moses Campus Suspended
Bronx, New York, United States, 10467
Roswell Park Cancer Institute Recruiting
Buffalo, New York, United States, 14263
Contact: Site Public Contact    800-767-9355    askroswell@roswellpark.org   
Principal Investigator: Tracey L. O'Connor         
Hematology Oncology Associates of Central New York-East Syracuse Recruiting
East Syracuse, New York, United States, 13057
Contact: Site Public Contact    315-472-7504      
Principal Investigator: Jeffrey J. Kirshner         
Glens Falls Hospital Recruiting
Glens Falls, New York, United States, 12801
Contact: Site Public Contact    518-926-6700      
Principal Investigator: Peter A. Kaufman         
Northwell Health/Center for Advanced Medicine Recruiting
Lake Success, New York, United States, 11042
Contact: Site Public Contact    516-734-8896      
Principal Investigator: Kit L. Cheng         
Hematology Oncology Associates of Central New York-Onondaga Hill Recruiting
Syracuse, New York, United States, 13215
Contact: Site Public Contact    315-472-7504      
Principal Investigator: Jeffrey J. Kirshner         
United States, North Carolina
UNC Lineberger Comprehensive Cancer Center Recruiting
Chapel Hill, North Carolina, United States, 27599
Contact: Site Public Contact    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: Trevor A. Jolly         
Southeastern Medical Oncology Center-Clinton Recruiting
Clinton, North Carolina, United States, 28328
Contact: Site Public Contact    919-587-9077    ecooke@cancersmoc.com   
Principal Investigator: Nagesh H. Jayaram         
Duke University Medical Center Recruiting
Durham, North Carolina, United States, 27710
Contact: Site Public Contact    888-275-3853      
Principal Investigator: Jeffrey Crawford         
Southeastern Medical Oncology Center-Goldsboro Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: Site Public Contact    919-587-9077    ecooke@cancersmoc.com   
Principal Investigator: Nagesh H. Jayaram         
Wayne Memorial Hospital Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: Site Public Contact    919-731-6687    ecooke@cancersmoc.com   
Principal Investigator: Nagesh H. Jayaram         
Southeastern Medical Oncology Center-Jacksonville Recruiting
Jacksonville, North Carolina, United States, 28546
Contact: Site Public Contact    910-353-0824    ecooke@cancersmoc.com   
Principal Investigator: Nagesh H. Jayaram         
Novant Health Oncology Specialists-Kernersville Recruiting
Kernersville, North Carolina, United States, 27284
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Novant Health Oncology Specialists-Mount Airy Recruiting
Mount Airy, North Carolina, United States, 27030
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
CarolinaEast Medical Center Recruiting
New Bern, North Carolina, United States, 28561
Contact: Site Public Contact    252-634-6589    lharrison@carolinaeasthealth.com   
Principal Investigator: William C. Taylor         
CarolinaEast Oncology and Hematology Associates Recruiting
New Bern, North Carolina, United States, 28562
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: William C. Taylor         
Novant Health Oncology Specialists-Statesville Recruiting
Statesville, North Carolina, United States, 28625
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Novant Health Oncology Specialists-Davidson County Recruiting
Thomasville, North Carolina, United States, 27360
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Novant Health Oncology Specialists-Wilkesboro Recruiting
Wilkesboro, North Carolina, United States, 28659
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Novant Health Forsyth Medical Center Recruiting
Winston-Salem, North Carolina, United States, 27103
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Novant Health Oncology Specialists Recruiting
Winston-Salem, North Carolina, United States, 27103
Contact: Site Public Contact    336-718-8335    asmarrs@novanthealth.org   
Principal Investigator: Judith O. Hopkins         
Wake Forest University Health Sciences Recruiting
Winston-Salem, North Carolina, United States, 27157
Contact: Site Public Contact    336-713-6771      
Principal Investigator: Heidi D. Klepin         
United States, North Dakota
Sanford Bismarck Medical Center Recruiting
Bismarck, North Dakota, United States, 58501
Contact: Site Public Contact    701-323-5760    OncologyClinicalTrialsFargo@sanfordhealth.org   
Principal Investigator: Preston D. Steen         
Essentia Health Cancer Center-South University Clinic Recruiting
Fargo, North Dakota, United States, 58103
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Sanford South University Medical Center Recruiting
Fargo, North Dakota, United States, 58103
Contact: Site Public Contact    701-234-6161      
Principal Investigator: Preston D. Steen         
Sanford Medical Center Fargo Recruiting
Fargo, North Dakota, United States, 58104
Contact: Site Public Contact    800-437-4010      
Principal Investigator: Preston D. Steen         
Sanford Broadway Medical Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Site Public Contact    701-323-5760    OncologyClinicalTrialsFargo@sanfordhealth.org   
Principal Investigator: Preston D. Steen         
Sanford Roger Maris Cancer Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Site Public Contact    701-234-6161    OncologyClinicalTrialsFargo@sanfordhealth.org   
Principal Investigator: Preston D. Steen         
Altru Cancer Center Recruiting
Grand Forks, North Dakota, United States, 58201
Contact: Site Public Contact    701-780-6520      
Principal Investigator: Grant R. Seeger         
Essentia Health - Jamestown Clinic Recruiting
Jamestown, North Dakota, United States, 58401
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
United States, Ohio
Mercy Health Perrysburg Cancer Center Recruiting
Perrysburg, Ohio, United States, 43551
Contact: Site Public Contact    419-479-5605    pshoup@toledoclinic.com   
Principal Investigator: Rex B. Mowat         
Mercy Saint Anne Hospital Recruiting
Toledo, Ohio, United States, 43623
Contact: Site Public Contact    419-407-1160      
Principal Investigator: Rex B. Mowat         
Toledo Clinic Cancer Centers-Toledo Recruiting
Toledo, Ohio, United States, 43623
Contact: Site Public Contact    800-444-3561      
Principal Investigator: Rex B. Mowat         
United States, Oklahoma
Mercy Hospital Oklahoma City Recruiting
Oklahoma City, Oklahoma, United States, 73120
Contact: Site Public Contact    405-752-3402      
Principal Investigator: Jay W. Carlson         
United States, Oregon
Saint Alphonsus Medical Center-Baker City Recruiting
Baker City, Oregon, United States, 97814
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Saint Charles Health System Recruiting
Bend, Oregon, United States, 97701
Contact: Site Public Contact    541-706-2909    nosall@stcharleshealthcare.org   
Principal Investigator: Alison K. Conlin         
Clackamas Radiation Oncology Center Recruiting
Clackamas, Oregon, United States, 97015
Contact: Site Public Contact    503-215-2614    CanRsrchStudies@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Oncology and Hematology Care Southeast Recruiting
Clackamas, Oregon, United States, 97015
Contact: Site Public Contact    503-215-2614    CanRsrchStudies@providence.org   
Principal Investigator: Alison K. Conlin         
Bay Area Hospital Recruiting
Coos Bay, Oregon, United States, 97420
Contact: Site Public Contact    541-269-8392    cherie.cox@bayareahospital.org   
Principal Investigator: Alison K. Conlin         
Providence Newberg Medical Center Recruiting
Newberg, Oregon, United States, 97132
Contact: Site Public Contact    503-215-2614    CanRsrchStudies@providence.org   
Principal Investigator: Alison K. Conlin         
Saint Alphonsus Medical Center-Ontario Recruiting
Ontario, Oregon, United States, 97914
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Benjamin T. Marchello         
Providence Portland Medical Center Recruiting
Portland, Oregon, United States, 97213
Contact: Site Public Contact    503-215-2614    CanRsrchStudies@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Saint Vincent Medical Center Recruiting
Portland, Oregon, United States, 97225
Contact: Site Public Contact    503-215-2614    CanRsrchStudies@providence.org   
Principal Investigator: Alison K. Conlin         
Saint Charles Health System-Redmond Recruiting
Redmond, Oregon, United States, 97756
Contact: Site Public Contact    541-706-2909      
Principal Investigator: Alison K. Conlin         
United States, Pennsylvania
Lehigh Valley Hospital-Cedar Crest Recruiting
Allentown, Pennsylvania, United States, 18103
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Lehigh Valley Hospital - Muhlenberg Recruiting
Bethlehem, Pennsylvania, United States, 18017
Contact: Site Public Contact    734-712-3671    stephanie.couch@stjoeshealth.org   
Principal Investigator: Elie G. Dib         
Christiana Care Health System-Concord Health Center Recruiting
Chadds Ford, Pennsylvania, United States, 19317
Contact: Site Public Contact    302-623-4450    KDempsey@christianacare.org   
Principal Investigator: Gregory A. Masters         
Geisinger Medical Center Recruiting
Danville, Pennsylvania, United States, 17822
Contact: Site Public Contact    570-271-5251    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Pocono Medical Center Recruiting
East Stroudsburg, Pennsylvania, United States, 18301
Contact: Site Public Contact    570-422-1700    ann.foster@lvhn.org   
Principal Investigator: Elie G. Dib         
Ephrata Cancer Center Recruiting
Ephrata, Pennsylvania, United States, 17522
Contact: Site Public Contact    717-721-4840      
Principal Investigator: Dan Sotirescu         
Ephrata Community Hospital Recruiting
Ephrata, Pennsylvania, United States, 17522
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Dan Sotirescu         
Adams Cancer Center Recruiting
Gettysburg, Pennsylvania, United States, 17325
Contact: Site Public Contact    877-441-7957      
Principal Investigator: Dan Sotirescu         
Cherry Tree Cancer Center Recruiting
Hanover, Pennsylvania, United States, 17331
Contact: Site Public Contact    877-441-7957      
Principal Investigator: Dan Sotirescu         
UPMC Pinnacle Harrisburg Recruiting
Harrisburg, Pennsylvania, United States, 17101
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Terry L. Evans         
UPMC Pinnacle Cancer Center/Community Osteopathic Campus Recruiting
Harrisburg, Pennsylvania, United States, 17109
Contact: Site Public Contact    717-724-6765    klitchfield@PINNACLEHEALTH.org   
Principal Investigator: Terry L. Evans         
Geisinger Medical Center-Cancer Center Hazleton Recruiting
Hazleton, Pennsylvania, United States, 18201
Contact: Site Public Contact    570-459-2901    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Lehigh Valley Hospital-Hazleton Recruiting
Hazleton, Pennsylvania, United States, 18201
Contact: Site Public Contact    570-501-1242      
Principal Investigator: Elie G. Dib         
Sechler Family Cancer Center Recruiting
Lebanon, Pennsylvania, United States, 17042
Contact: Site Public Contact    717-741-8303    doxenberg@wellspan.org   
Principal Investigator: Dan Sotirescu         
Geisinger Medical Oncology-Lewisburg Recruiting
Lewisburg, Pennsylvania, United States, 17837
Contact: Site Public Contact    570-374-8555    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
University of Pittsburgh Cancer Institute (UPCI) Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Site Public Contact    412-647-8073      
Principal Investigator: Terry L. Evans         
Geisinger Cancer Services-Pottsville Recruiting
Pottsville, Pennsylvania, United States, 17901
Contact: Site Public Contact    800-275-6401    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Guthrie Medical Group PC-Robert Packer Hospital Recruiting
Sayre, Pennsylvania, United States, 18840
Contact: Site Public Contact    800-836-0388      
Principal Investigator: Philip A. Lowry         
Community Medical Center Recruiting
Scranton, Pennsylvania, United States, 18510
Contact: Site Public Contact    570-703-4768    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Geisinger Medical Oncology-Selinsgrove Recruiting
Selinsgrove, Pennsylvania, United States, 17870
Contact: Site Public Contact    570-374-8555    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Geisinger Medical Group Recruiting
State College, Pennsylvania, United States, 16801
Contact: Site Public Contact    570-271-5251    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
Geisinger Wyoming Valley/Henry Cancer Center Recruiting
Wilkes-Barre, Pennsylvania, United States, 18711
Contact: Site Public Contact    570-271-5251    HemonCCTrials@geisinger.edu   
Principal Investigator: Victor G. Vogel         
UPMC Susquehanna Recruiting
Williamsport, Pennsylvania, United States, 17701
Contact: Site Public Contact    800-598-4282      
Principal Investigator: Terry L. Evans         
WellSpan Health-York Cancer Center Recruiting
York, Pennsylvania, United States, 17403
Contact: Site Public Contact    877-441-7957      
Principal Investigator: Dan Sotirescu         
WellSpan Health-York Hospital Recruiting
York, Pennsylvania, United States, 17403
Contact: Site Public Contact    877-441-7957      
Principal Investigator: Dan Sotirescu         
United States, South Carolina
Medical University of South Carolina Recruiting
Charleston, South Carolina, United States, 29425
Contact: Site Public Contact    843-792-9321    hcc-clinical-trials@musc.edu   
Principal Investigator: Frank J. Brescia         
Lexington Medical Center Recruiting
West Columbia, South Carolina, United States, 29169
Contact: Site Public Contact    803-936-8050      
Principal Investigator: Steven A. Madden         
United States, South Dakota
Rapid City Regional Hospital Recruiting
Rapid City, South Dakota, United States, 57701
Contact: Site Public Contact    605-716-3982    research@rcrh.org   
Principal Investigator: Kathryn A. Arrambide         
Sanford Cancer Center Oncology Clinic Recruiting
Sioux Falls, South Dakota, United States, 57104
Contact: Site Public Contact    605-312-3320    OncologyClinicTrialsSF@sanfordhealth.org   
Principal Investigator: Preston D. Steen         
Sanford USD Medical Center - Sioux Falls Recruiting
Sioux Falls, South Dakota, United States, 57117-5134
Contact: Site Public Contact    605-312-3320    OncologyClinicalTrialsSF@SanfordHealth.org   
Principal Investigator: Preston D. Steen         
United States, Utah
Farmington Health Center Recruiting
Farmington, Utah, United States, 84025
Contact: Site Public Contact    888-424-2100    cancerinfo@hci.utah.edu   
Principal Investigator: Elizabeth M. Prystas         
Huntsman Cancer Institute/University of Utah Recruiting
Salt Lake City, Utah, United States, 84112
Contact: Site Public Contact    888-424-2100    cancerinfo@hci.utah.edu   
Principal Investigator: Elizabeth M. Prystas         
South Jordan Health Center Recruiting
South Jordan, Utah, United States, 84009
Contact: Site Public Contact    888-424-2100    cancerinfo@hci.utah.edu   
Principal Investigator: Elizabeth M. Prystas         
United States, Vermont
Central Vermont Medical Center/National Life Cancer Treatment Recruiting
Berlin, Vermont, United States, 05602
Contact: Site Public Contact    802-225-5400      
Principal Investigator: Peter A. Kaufman         
University of Vermont Medical Center Recruiting
Burlington, Vermont, United States, 05401
Contact: Site Public Contact    802-656-4101    rpo@uvm.edu   
Principal Investigator: Peter A. Kaufman         
University of Vermont and State Agricultural College Recruiting
Burlington, Vermont, United States, 05405
Contact: Site Public Contact    802-656-8990    rpo@uvm.edu   
Principal Investigator: Peter A. Kaufman         
United States, Virginia
Sovah Health Martinsville Recruiting
Martinsville, Virginia, United States, 24115
Contact: Site Public Contact    276-666-7827    sharon.hubbard@lpnt.net   
Principal Investigator: Michael S. Steinberg         
Bon Secours Memorial Regional Medical Center Recruiting
Mechanicsville, Virginia, United States, 23116
Contact: Site Public Contact    804-893-8611    Melissa_Godsey@bshsi.org   
Principal Investigator: William J. Irvin         
Bon Secours Saint Francis Medical Center Recruiting
Midlothian, Virginia, United States, 23114
Contact: Site Public Contact    804-893-8611    Melissa_Godsey@bshsi.org   
Principal Investigator: William J. Irvin         
Bon Secours DePaul Medical Center Recruiting
Norfolk, Virginia, United States, 23505
Contact: Site Public Contact    804-893-8611    Melissa_Godsey@bshsi.org   
Principal Investigator: William J. Irvin         
Bon Secours Saint Mary's Hospital Recruiting
Richmond, Virginia, United States, 23226
Contact: Site Public Contact    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: William J. Irvin         
Virginia Cancer Institute Recruiting
Richmond, Virginia, United States, 23230
Contact: Site Public Contact    804-287-3000    david.trent@comcast.net   
Principal Investigator: Hetal R. Vachhani         
Virginia Commonwealth University/Massey Cancer Center Recruiting
Richmond, Virginia, United States, 23298
Contact: Site Public Contact       mwellons@vcu.edu   
Principal Investigator: Hetal R. Vachhani         
VCU Community Memorial Health Center Recruiting
South Hill, Virginia, United States, 23970
Contact: Site Public Contact    434-774-2442    sherman.baker@vcuhealth.org   
Principal Investigator: Hetal R. Vachhani         
Bon Secours Health Center at Harbour View Recruiting
Suffolk, Virginia, United States, 23435
Contact: Site Public Contact    757-398-4234    melissa_eckert@bshsi.org   
Principal Investigator: William J. Irvin         
Shenandoah Oncology PC Recruiting
Winchester, Virginia, United States, 22601
Contact: Site Public Contact    540-662-1108    William.Houck@usoncology.com   
Principal Investigator: Hetal R. Vachhani         
United States, Washington
Providence Regional Cancer System-Aberdeen Recruiting
Aberdeen, Washington, United States, 98520
Contact: Site Public Contact    360-412-8958    deidre.dillon@providence.org   
Principal Investigator: Alison K. Conlin         
PeaceHealth Saint Joseph Medical Center Recruiting
Bellingham, Washington, United States, 98225
Contact: Site Public Contact    360-715-4133    mjohnson9@peacehealth.org   
Principal Investigator: Alison K. Conlin         
Providence Regional Cancer System-Centralia Recruiting
Centralia, Washington, United States, 98531
Contact: Site Public Contact    360-412-8958    deidre.dillon@providence.org   
Principal Investigator: Alison K. Conlin         
Swedish Cancer Institute-Edmonds Recruiting
Edmonds, Washington, United States, 98026
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
Providence Regional Cancer Partnership Recruiting
Everett, Washington, United States, 98201
Contact: Site Public Contact    425-261-3529    marilyn.birchman@providence.org   
Principal Investigator: Alison K. Conlin         
Swedish Cancer Institute-Issaquah Recruiting
Issaquah, Washington, United States, 98029
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
Kadlec Clinic Hematology and Oncology Recruiting
Kennewick, Washington, United States, 99336
Contact: Site Public Contact    509-783-4637    research@kadlecmed.org   
Principal Investigator: Alison K. Conlin         
Providence Regional Cancer System-Lacey Recruiting
Lacey, Washington, United States, 98503
Contact: Site Public Contact    360-412-8958    deidre.dillon@providence.org   
Principal Investigator: Alison K. Conlin         
PeaceHealth Saint John Medical Center Recruiting
Longview, Washington, United States, 98632
Contact: Site Public Contact    360-514-2016    kmakin-bond@peacehealth.org   
Principal Investigator: Alison K. Conlin         
Pacific Gynecology Specialists Recruiting
Seattle, Washington, United States, 98104
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
Swedish Medical Center-Ballard Campus Recruiting
Seattle, Washington, United States, 98107
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
Kaiser Permanente Washington Suspended
Seattle, Washington, United States, 98112
Swedish Medical Center-First Hill Recruiting
Seattle, Washington, United States, 98122-4307
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
Swedish Medical Center-Cherry Hill Recruiting
Seattle, Washington, United States, 98122-5711
Contact: Site Public Contact    206-215-3086    PCRC-NCORP@Swedish.org   
Principal Investigator: Alison K. Conlin         
PeaceHealth United General Medical Center Recruiting
Sedro-Woolley, Washington, United States, 98284
Contact: Site Public Contact    360-788-8240      
Principal Investigator: Alison K. Conlin         
Providence Regional Cancer System-Shelton Recruiting
Shelton, Washington, United States, 98584
Contact: Site Public Contact    360-412-8958    deidre.dillon@providence.org   
Principal Investigator: Alison K. Conlin         
PeaceHealth Southwest Medical Center Recruiting
Vancouver, Washington, United States, 98664
Contact: Site Public Contact    360-514-3940    kmakin-bond@peacehealth.org   
Principal Investigator: Alison K. Conlin         
Providence Saint Mary Regional Cancer Center Recruiting
Walla Walla, Washington, United States, 99362
Contact: Site Public Contact    509-897-5993    Cheryl.Dodd@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Regional Cancer System-Yelm Recruiting
Yelm, Washington, United States, 98597
Contact: Site Public Contact    360-412-8958    deidre.dillon@providence.org   
Principal Investigator: Alison K. Conlin         
United States, Wisconsin
Duluth Clinic Ashland Recruiting
Ashland, Wisconsin, United States, 54806
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Northwest Wisconsin Cancer Center Recruiting
Ashland, Wisconsin, United States, 54806
Contact: Site Public Contact    218-786-3308    CancerTrials@EssentiaHealth.org   
Principal Investigator: Bret E. Friday         
Marshfield Clinic-Chippewa Center Recruiting
Chippewa Falls, Wisconsin, United States, 54729
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Medical Center-EC Cancer Center Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic - Ladysmith Center Recruiting
Ladysmith, Wisconsin, United States, 54848
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Medical Center-Marshfield Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic-Minocqua Center Recruiting
Minocqua, Wisconsin, United States, 54548
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Cancer Center of Western Wisconsin Recruiting
New Richmond, Wisconsin, United States, 54017
Contact: Site Public Contact    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Marshfield Medical Center-Rice Lake Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic Stevens Point Center Recruiting
Stevens Point, Wisconsin, United States, 54482
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic-Wausau Center Recruiting
Wausau, Wisconsin, United States, 54401
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic - Weston Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Marshfield Clinic - Wisconsin Rapids Center Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Site Public Contact    800-782-8581    oncology.clinical.trials@marshfieldresearch.org   
Principal Investigator: Demet Gokalp Yasar         
Sponsors and Collaborators
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)
Investigators
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Study Chair: Mina Sedrak, MD, MS City of Hope Comprehensive Cancer Center

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Responsible Party: Alliance for Clinical Trials in Oncology
ClinicalTrials.gov Identifier: NCT03633331     History of Changes
Other Study ID Numbers: A171601
NCI-2017-01596 ( Registry Identifier: NCI Clinical Trial Reporting Program )
First Posted: August 16, 2018    Key Record Dates
Last Update Posted: June 20, 2019
Last Verified: June 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: Yes

Additional relevant MeSH terms:
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Breast Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Skin Diseases
Letrozole
Fulvestrant
Palbociclib
Estrogens
Antineoplastic Agents
Aromatase Inhibitors
Steroid Synthesis Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Estrogen Antagonists
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Hormones
Antineoplastic Agents, Hormonal
Estrogen Receptor Antagonists
Protein Kinase Inhibitors