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Taekwondo Training and Postmenopausal Women With Stage-2 Hypertension

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03544307
Recruitment Status : Completed
First Posted : June 1, 2018
Results First Posted : August 5, 2019
Last Update Posted : November 10, 2020
Sponsor:
Collaborator:
University of Nebraska
Information provided by (Responsible Party):
Sang-Ho Lee, Kosin University

Study Description
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Brief Summary:
Aging is associated with hormonal imbalances and progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on hormonal balance and the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a 12-week Taekwondo training program on blood catecholamines, arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), resting heart rate, and muscular strength in postmenopausal women with stage 2 hypertension.

Condition or disease Intervention/treatment Phase
Menopause Hypertension Behavioral: Taekwondo training Not Applicable

Detailed Description:

Using a parallel experimental design, participants were randomly assigned to either a Taekwondo exercise training group (n=10) or non-exercising control group (n=10) for 12 weeks.

Participant in the Taekwondo training group trained 3 days/week for 60 minutes per session, and the intensity progressed weekly. Participants in the control group performed no exercise intervention.

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: Parallel design with treatment group and control
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Taekwondo Training Reduces Blood Catecholamine Levels and Arterial Stiffness in Postmenopausal Women With Stage-2 Hypertension
Actual Study Start Date : May 1, 2017
Actual Primary Completion Date : March 1, 2018
Actual Study Completion Date : March 1, 2018

Resource links provided by the National Library of Medicine


Arms and Interventions
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Arm Intervention/treatment
Experimental: Taekwondo Training
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
 Behavioral: Taekwondo training
Exercise group
No Intervention: Control
Sedentary control asked not to exercise


Outcome Measures
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Primary Outcome Measures :
  1. Blood Epinephrine Levels [ Time Frame: 12-weeks ]
  2. Blood Norepinephrine Levels [ Time Frame: 12-weeks ]

Secondary Outcome Measures :
  1. Arterial Stiffness [ Time Frame: 12-weeks ]
    Pulse Wave Velocity

  2. Systolic Blood Pressure [ Time Frame: 12-weeks ]
  3. Hand Grip Strength [ Time Frame: 12-weeks ]
  4. Diastolic Blood Pressure [ Time Frame: 12-weeks ]
  5. Leg Strength [ Time Frame: 12-weeks ]

Eligibility Criteria
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Ages Eligible for Study:   65 Years to 85 Years   (Older Adult)
Sexes Eligible for Study:   Female
Gender Based Eligibility:   Yes
Gender Eligibility Description:   gender identity
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Be diagnosed with stage-2 hypertension
  • Be postmenopausal
  • Be between 65 and 85 years old

Exclusion Criteria:

  • Known cardiovascular, metabolic or renal diseases
  • Physical limitations that prohibit exercise
  • Participates in regular exercise
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03544307


Locations
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United States, Nebraska
University of Nebraska Omaha
Omaha, Nebraska, United States, 68182
Sponsors and Collaborators
Kosin University
University of Nebraska
Investigators
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Principal Investigator: Song Park University of Nebraska
  Study Documents (Full-Text)

Documents provided by Sang-Ho Lee, Kosin University:
Study Protocol and Statistical Analysis Plan  [PDF] March 25, 2019

More Information
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Responsible Party: Sang-Ho Lee, Principal Investigator, Kosin University
ClinicalTrials.gov Identifier: NCT03544307    
Other Study ID Numbers: TaekwondoMenopause
First Posted: June 1, 2018    Key Record Dates
Results First Posted: August 5, 2019
Last Update Posted: November 10, 2020
Last Verified: November 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Sang-Ho Lee, Kosin University:
Taekwondo
Menopause
Hypertension
Arterial Stiffness
Blood Catecholamines
Additional relevant MeSH terms:
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Hypertension
Vascular Diseases
Cardiovascular Diseases