Superior Gluteal Neuropathy -Total Hip Arthroplasty

• ClinicalTrials.gov Identifier: NCT03492684
• Recruitment Status: Unknown
• First Posted: April 10, 2018
• Last Update Posted: April 10, 2018
• Sponsor: Assiut University
• Information provided by (Responsible Party): Mohamed Hamed Mohamed, Assiut University

Study Description

Brief Summary:

A prospective study of 50 consecutive patients undergoing total hip arthroplasty, to establish whether there greater incidence of injury to the superior gluteal nerve associated with a particular approach (modified direct lateral approach). The patients will be assessed clinically and electrophysiologically before and after the operation through one year.

Condition or disease	Intervention/treatment
ElectroPhys: Mononeuropathy	Procedure: total hip arthroplasty

Detailed Description:

Neurological complications following total hip arthroplasty are uncommon, and their impact ranges from transient and trivial to permanent and devastating.

In general, the prevalence rate of neurologic injury after primary hip arthroplasty is estimated as 0.7-3.5% , whereas it may increase up to 7.6% after revision hip arthroplasty.

Direct or indirect injuries of nerves may occur during operative exposure and subsequent procedures. Injuries to the peripheral nerves can come about in several ways: laceration, ischemia, mechanical deformation from compression or distraction, or a combination of these causes.

Peripheral nerve injuries can involve either distant sites or nerves in the immediate vicinity of the hip joint. Sciatic nerve injury is the most common nerve to be injured following total hip arthroplasty. Femoral nerve injury is much less common and is associated with an anterior approach. Its diagnosis is often delayed, but the prognosis is generally better than with sciatic nerve injury.

The direct lateral approach to the hip was described by Hardinge and is based on the observation that the gluteus medius and vastus lateralis are in functional continuity through the thick tendinous periosteum covering the greater trochanter.

This approach involves splitting the gluteus medius and retracting a portion of the muscle anteriorly in continuity with part of the vastus lateralis. It avoids trochanteric osteotomy, but the neurovascular supply of gluteus medius and tensor fascia lata is vulnerable.

The superior gluteal nerve may be compromised during total hip arthroplasty done through the direct lateral approach of Hardinge which puts this nerve at risk when the gluteus medius is split and retracted anteriorly.

The function of the abductors may be impaired after operation if there is damage to the superior gluteal nerve or if the muscle flap is reattached inadequately to the trochanter.

Study Design

• Study Type: Observational
• Estimated Enrollment: 50 participants
• Observational Model: Case-Only
• Time Perspective: Prospective
• Official Title: Study of Superior Gluteal Mononeuropathy After Total Hip Arthroplasty Through Modified Direct Lateral Approach
• Estimated Study Start Date: September 1, 2018
• Estimated Primary Completion Date: September 1, 2019
• Estimated Study Completion Date: September 1, 2019

Groups and Cohorts

Intervention Details:

• Procedure: total hip arthroplasty
  total hip arthroplasty and EMG
  Other Name: electrophysiological study

Outcome Measures

Primary Outcome Measures :

1. Number of participants with failure of initial intervention [ Time Frame: one year ]
   prospective case series study study of Superior gluteal mononeuropathy after total hip arthroplasty through modified direct lateral approach by EMG studies

Eligibility Criteria

• Ages Eligible for Study: 18 Years to 80 Years (Adult, Older Adult)
• Sexes Eligible for Study: All
• Sampling Method: Non-Probability Sample

Study Population

• Age: adults
• Sex: both males and female
• Operation: unilateral primary total hip replacement.

Criteria

Inclusion Criteria:

• Age: adults
• Sex: both males and female
• Operation: unilateral primary total hip replacement

Exclusion Criteria:

• Patient refusal
• Patients with pre-existing neuromuscular abnormality
• Preoperative immobility
• patient with bilateral total hip arthroplasty or hip pathology
• Revision hip arthroplasty

Contacts and Locations

Contacts

Contact: Mohamed hamed mohamed; +0201146962067; dr.mohamedelhamed@gmail.com

Sponsors and Collaborators

Assiut University

Investigators

• Principal Investigator: mohamed hamed mohamed; Assiut University

More Information

Publications:

Edwards BN, Tullos HS, Noble PC. Contributory factors and etiology of sciatic nerve palsy in total hip arthroplasty. Clin Orthop Relat Res. 1987 May;(218):136-41.

Yang IH. Neurovascular Injury in Hip Arthroplasty. Hip Pelvis. 2014 Jun;26(2):74-8. doi: 10.5371/hp.2014.26.2.74. Epub 2014 Jun 30. Review.

Solheim LF, Hagen R. Femoral and sciatic neuropathies after total hip arthroplasty. Acta Orthop Scand. 1980 Jun;51(3):531-4.

Schmalzried TP, Amstutz HC, Dorey FJ. Nerve palsy associated with total hip replacement. Risk factors and prognosis. J Bone Joint Surg Am. 1991 Aug;73(7):1074-80.

• Responsible Party: Mohamed Hamed Mohamed, DR.mohamed hamed, Assiut University
• ClinicalTrials.gov Identifier: NCT03492684
• Other Study ID Numbers: neuropathy - hip arthroplasty
• First Posted: April 10, 2018
• Last Update Posted: April 10, 2018
• Last Verified: April 2018

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Mohamed Hamed Mohamed, Assiut University:

nerve injury after total hip arthroplasty

Additional relevant MeSH terms:

Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases