Impact of Medication Reconciliation at Discharge on Potentially Inappropriate Medications in the Elderly : Community-hospital Coordination (ICM2SA)

• ClinicalTrials.gov Identifier: NCT03415113
• Recruitment Status: Completed
• First Posted: January 30, 2018
• Last Update Posted: January 30, 2018
• Sponsor: Centre Hospitalier Universitaire, Amiens
• Information provided by (Responsible Party): Centre Hospitalier Universitaire, Amiens

Study Description

Brief Summary:

The geriatric population is exposed to poly-medication. Furthermore, old people have important pharmacodynamic and pharmacokinetic changes that expose to much drug iatrogenic. Adverse drug effects are a great cause for hospitalization that is why the knowledge of the complete list of medications taken by the patient is necessary. The poly-medication in elderly can lead to extremely serious clinical consequences and significant costs. Reference documents specific to geriatrics guide the doctor in therapeutic choices. On the one hand, the Laroche's criteria lists all PIM of the French pharmacopoeia in elderly. On the other hand, STOPP/START criteria are a tool for detect PIM listing inappropriate drugs and criteria of potentially drug omissions. This has been validated in French language. It is important that any changes proposed by the geriatrician resulting in just prescription is sustainable beyond the hospitalization to prevent the recurrence of adverse effects. Effective community-hospital coordination is essential.

Medication reconciliation is defined as the formal process of checking the complete, accurate list of a patient's previous medication - including drug name, dosage, frequency, and route - and comparing it with the prescription after a transition of care (on admission, after transfer to another medical unit, and/or at discharge).

Two groups of patients will be created, one for which medication reconciliation at discharge will be practiced and the other a similar process but not standardized. Four to eight weeks after the discharge, the member of the pharmacy team is calling the usual community pharmacy to get the first non-hospital prescription by fax and compare the number of PIM with the prescription before hospitalization.

Condition or disease
Hospital; Geriatric

Study Design

• Study Type: Observational
• Actual Enrollment: 60 participants
• Observational Model: Other
• Time Perspective: Prospective
• Official Title: Impact of Medication Reconciliation at Discharge on Potentially Inappropriate Medications in the Elderly : Community-hospital Coordination. ICM2SA
• Actual Study Start Date: April 14, 2016
• Actual Primary Completion Date: September 30, 2016
• Actual Study Completion Date: September 30, 2016

Groups and Cohorts

Outcome Measures

Primary Outcome Measures :

1. Quantification of potentially inappropriate medication prescription [ Time Frame: 4 or 8 weeks ]
   Quantification of potentially inappropriate medication on the first non-hospital

Eligibility Criteria

• Ages Eligible for Study: 75 Years and older (Older Adult)
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No
• Sampling Method: Probability Sample

Study Population

Geriatic population

Criteria

Inclusion Criteria:

• Male or female, age ≥ 75 years
• Pharmaceutical interview at the medication reconciliation at admission in Geriatrics Acute Care Unit.
• ≥ one PIM on the prescription before admission
• Identification of the usual referent community pharmacist
• Output of the unit by a return home
• Affiliation to a social security scheme

Exclusion Criteria:

• Patients undergoing a regime of legal protection.
• Patients unable to cooperate in pharmaceutical interview at the medication reconciliation at admission whatever reason.
• Refusal to participate in the study.
• Output of the unit by transfering to another care unit or death

Contacts and Locations

Sponsors and Collaborators

Centre Hospitalier Universitaire, Amiens

Investigators

• Principal Investigator: Guillaume DESCHASSE, MD; CHU Amiens

More Information

• Responsible Party: Centre Hospitalier Universitaire, Amiens
• ClinicalTrials.gov Identifier: NCT03415113
• Other Study ID Numbers: PI2016_843_0003
• First Posted: January 30, 2018
• Last Update Posted: January 30, 2018
• Last Verified: January 2018

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Centre Hospitalier Universitaire, Amiens:

Medication reconciliation at discharge, potentially inappropriate medications, elderly.