Prevalence and Clinical Characteristics of Patients With Jackhammer Esophagus and Symptoms of Gastroesophageal Reflux Disease
|ClinicalTrials.gov Identifier: NCT03347903|
Recruitment Status : Completed
First Posted : November 20, 2017
Last Update Posted : November 21, 2017
Gastroesophageal reflux disease (GERD) is involved in the development of esophageal motility disorders like Jackhammer esophagus (JE), a novel hypercontractile condition that was associated with progression to achalasia and limited outcomes following surgical anti-reflux therapy.
This trial was designed to assess the prevalence and characteristics of JE in patients with typical symptoms of GERD and responsiveness to PPI therapy.
|Condition or disease|
|Esophageal Motility Disorders|
|Study Type :||Observational|
|Actual Enrollment :||37 participants|
|Official Title:||Prevalence and Clinical Characteristics of Patients With Jackhammer Esophagus and Symptoms of Gastroesophageal Reflux Disease|
|Actual Study Start Date :||January 1, 2014|
|Primary Completion Date :||May 30, 2017|
|Study Completion Date :||May 30, 2017|
- Prevalence of Jackhammer esophagus in patients referred with symptoms of gastroesophageal reflux disease [ Time Frame: January 2014- May 2017 ]All patients that are referred to our center with symptoms of gastroesophageal reflux disease routinely undergo high-resolution manometry. We assess how many patients are diagnosed with Jackhammer esophagus
- Symptom perception [ Time Frame: January 2014- May 2017 ]We assess which symptoms are perceived by the patients diagnosed with Jackhammer esophagus. All data are observed during an interview at the high-resolution manometry
- Prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus [ Time Frame: Januar 2014- May 2017 ]All patients that are referred to our center are evaluated for gastroesophageal reflux disease. We assess the prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus diagnosed by ambulatory pH monitoring.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03347903
|Principal Investigator:||Sebastian Schoppmann, MD||Vice Chair of Department of General Surgery|