Boston Birth Cohort Study
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|ClinicalTrials.gov Identifier: NCT03228875|
Recruitment Status : Recruiting
First Posted : July 25, 2017
Last Update Posted : February 13, 2020
|Condition or disease|
|Preterm Birth Birthweight Pregnancy Complications Pediaric Health Problems|
Any woman admitted to the Labor and Delivery floor at the Boston Medical Center (BMC) who delivers a singleton live infant and meets our case (gestational age <37 weeks or birthweight <2,500 grams) or control (full term birth with birthweight >2,500 grams) criteria will be eligible.
Postnatal follow-up of enrolled children is conducted from birth to age 21 years.
The Boston Birth Cohort has high-quality biospecimen collection, and comprehensive epidemiological, clinical, and environmental exposure data via standardized questionnaire interview, measurements, and review of the electronic medical records.
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||24000 participants|
|Target Follow-Up Duration:||21 Years|
|Official Title:||Early Life Origins of Pediatric and Adult Diseases: Boston Birth Cohort Study|
|Actual Study Start Date :||October 1998|
|Estimated Primary Completion Date :||December 2025|
|Estimated Study Completion Date :||December 2025|
- preterm birth [ Time Frame: at birth ]preterm birth is defined as gestational age less than 37 weeks
- birthweight [ Time Frame: at birth ]low birthweight is defined as birthweight less than 2500g.
- pregnancy complications [ Time Frame: at delivery ]multiple pregnancy complications are examined including gestational diabetes, hypertensive disorders during pregnancy
- child overweight or obesity [ Time Frame: from birth to 21 years ]multiple child health outcomes are examined including food allergy, asthma, to understand the early life origin and risk factors of child's overweight or obesity
- child hypertension [ Time Frame: from 3 years to 21 years ]to understand the early life origin and risk factors of child's blood pressure
- Child neuro-developmental outcomes [ Time Frame: from birth to 21 years ]To investigate the early life origin and risk factors of child's neuro-developmental outcomes, including ASD, ADHD
- food allergy, asthma [ Time Frame: from birth to 21 years ]To investigate the early life origin and risk factors of child's food allergy, asthma
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03228875
|Contact: Xiaobin Wang, MD, ScDemail@example.com|
|United States, Massachusetts|
|Boston Medical Center||Recruiting|
|Boston, Massachusetts, United States, 02118|
|Contact: Colleen Pearson, BA 617-414-5133 Colleen.firstname.lastname@example.org|
|Principal Investigator:||Xiaobin Wang, MD, ScD||Johns Hopkins Bloomberg School of Public Health|