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Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance in Adults

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03166592
Recruitment Status : Unknown
Verified August 2017 by Ahmed Mohamed Abbas, Assiut University.
Recruitment status was:  Recruiting
First Posted : May 25, 2017
Last Update Posted : August 16, 2017
Sponsor:
Information provided by (Responsible Party):
Ahmed Mohamed Abbas, Assiut University

Study Description
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Brief Summary:

Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit.

Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement.

Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging


Condition or disease Intervention/treatment
Brain Tumor Device: Magnetic resonance imaging with contrast

Study Design
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Study Type : Observational
Estimated Enrollment : 150 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: Impact of Advanced Neuroimaging Techniques in Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance Diagnostic Strategy in Adults
Actual Study Start Date : July 1, 2017
Estimated Primary Completion Date : July 2019
Estimated Study Completion Date : September 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: MRI Scans

Groups and Cohorts
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Intervention Details:
  • Device: Magnetic resonance imaging with contrast
    injection of gadolinium contrast then acquisition of images with magnetic resonance imaging then spectroscopy

Outcome Measures
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Primary Outcome Measures :
  1. Number of patients with malignant masses [ Time Frame: 1 hour ]
    sensitivity of the magnetic resonance spectroscopy in diagnosis of brain malignant masses


Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
All Magnetic resonance imaging detected brain cases referred from Neurosurgery & Neuropsychiatry departments as well as Outpatient clinics
Criteria

  1. Inclusion criteria:

    * An intra axial space occupying lesion/lesions detected on conventional structural imaging

  2. Exclusion criteria:

    • MRI contraindications (as pace maker or claustrophobia).
    • Contrast hypersensitivity
    • Impaired renal function.
    • Pediatric age group
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03166592


Contacts
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Contact: Ahmed Abbas, MD 00201003385183 bmr90@hotmail.com

Locations
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Egypt
Ahmed Abbas Recruiting
Assiut, Cairo, Egypt, 002
Contact: ahmed abbas, MD       bmr90@hotmail.com   
Contact: ahmed abbas         
Assiut Faculty of Medicine Recruiting
Assiut, Egypt
Contact: Ahmed Abbas, MD    00201003385183    bmr90@hotmail.com   
Sponsors and Collaborators
Assiut University
More Information
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Responsible Party: Ahmed Mohamed Abbas, principal investigator, Assiut University
ClinicalTrials.gov Identifier: NCT03166592    
Other Study ID Numbers: IAM
First Posted: May 25, 2017    Key Record Dates
Last Update Posted: August 16, 2017
Last Verified: August 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Neoplasms by Site
 Neoplasms
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases