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Pembrolizumab in Treating Patients With Triple-Negative Breast Cancer

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02954874
Recruitment Status : Recruiting
First Posted : November 4, 2016
Last Update Posted : January 11, 2018
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
This randomized phase III trial studies how well pembrolizumab works in treating triple-negative breast cancer. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread.

Condition or disease Intervention/treatment Phase
Estrogen Receptor Negative HER2/Neu Negative Invasive Breast Carcinoma Progesterone Receptor Negative Stage 0 Breast Cancer AJCC v6 and v7 Stage I Breast Cancer AJCC v7 Stage IA Breast Cancer AJCC v7 Stage IB Breast Cancer AJCC v7 Stage II Breast Cancer AJCC v6 and v7 Stage IIA Breast Cancer AJCC v6 and v7 Stage IIB Breast Cancer AJCC v6 and v7 Stage III Breast Cancer AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIC Breast Cancer AJCC v7 Triple-Negative Breast Carcinoma Other: Laboratory Biomarker Analysis Other: Patient Observation Biological: Pembrolizumab Other: Quality-of-Life Assessment Other: Questionnaire Administration Radiation: Radiation Therapy Phase 3

Detailed Description:

PRIMARY OBJECTIVES:

I. To compare invasive disease-free survival (IDFS) of patients with triple-negative breast cancer (TNBC) who have either >= 1 cm residual invasive breast cancer and/or positive lymph nodes (> ypN+) after neoadjuvant chemotherapy randomized to receive 1 year of MK-3475 (pembrolizumab) adjuvant therapy compared to no MK-3475 (pembrolizumab), in both the entire study population and also in the PD-L1 positive subset.

SECONDARY OBJECTIVES:

I. To compare the effects of MK-3475 (pembrolizumab) on overall survival (OS) and distant recurrence-free survival (DRFS) between the two randomized arms for the PD-L1 positive patients and then all patients.

II. To assess the toxicity and tolerability of MK-3475 (pembrolizumab) in this patient population with or without radiation therapy.

TERTIARY OBJECTIVES:

I. To examine the association between biomarkers of inflammation and quality of life and patient reported outcomes between the two groups during and at the end of therapy.

II. To examine the long-term and late effects of treatment on patient-reported outcomes.

III. To collect tissue and whole blood for processing and banking in anticipation of future correlative studies in this patient population.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I (OBSERVATION): Patients receive no treatment but are monitored at standard clinical intervals during first year after randomization. Patients are examined every 12 weeks for 1 year, and every 6 months for 4 years, then annually for 5 years.

ARM II (PEMROLIZUMAB): Patients receive pembrolizumab intravenously (IV) over 30 minutes on days 1 and 22. Courses repeat every 42 days for 52 weeks in the absence of disease progression or unacceptable toxicity.

All patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.

After completion of study treatment, patients are followed up to 10 years.


Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 1000 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With ≥ 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy
Actual Study Start Date : November 15, 2016
Estimated Primary Completion Date : May 31, 2026
Estimated Study Completion Date : May 31, 2026

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Breast Cancer
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: Arm I (observation)
Patients receive no treatment but are monitored at standard clinical intervals during first year after randomization. Patients are examined every 12 weeks for 1 year, every 6 months for 4 years, and then annually for 5 years. Patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Patient Observation
Undergo standard monitoring
Other Names:
  • Active Surveillance
  • deferred therapy
  • expectant management
  • observation
  • Watchful Waiting
Other: Quality-of-Life Assessment
Ancillary studies
Other Name: Quality of Life Assessment
Other: Questionnaire Administration
Ancillary studies
Radiation: Radiation Therapy
Undergo radiation therapy
Other Names:
  • Cancer Radiotherapy
  • Irradiate
  • Irradiated
  • irradiation
  • RADIATION
  • Radiotherapeutics
  • radiotherapy
  • RT
  • Therapy, Radiation
Experimental: Arm II (pembrolizumab)
Patients receive pembrolizumab IV over 30 minutes on days 1 and 22. Courses repeat every 42 days for 52 weeks in the absence of disease progression or unacceptable toxicity. Patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.
Other: Laboratory Biomarker Analysis
Correlative studies
Biological: Pembrolizumab
Given IV
Other Names:
  • Keytruda
  • Lambrolizumab
  • MK-3475
  • SCH 900475
Other: Quality-of-Life Assessment
Ancillary studies
Other Name: Quality of Life Assessment
Other: Questionnaire Administration
Ancillary studies
Radiation: Radiation Therapy
Undergo radiation therapy
Other Names:
  • Cancer Radiotherapy
  • Irradiate
  • Irradiated
  • irradiation
  • RADIATION
  • Radiotherapeutics
  • radiotherapy
  • RT
  • Therapy, Radiation


Outcome Measures

Primary Outcome Measures :
  1. Invasive disease-free survival (IDFS) [ Time Frame: From date of randomization to date of first invasive recurrence, second invasive primary cancer (breast or not), or death due to any cause, assessed up to 10 years ]
    The distributions of IDFS will be estimated using the Kaplan-Meier method, with 95% confidence intervals (CI) calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate. Secondary analyses of IDFS will be performed to describe consistency or divergence across subgroups. This will include a forest plot of treatment hazard ratios and associated 95% confidence intervals for each level of the str

  2. Physical function reported by patients measured by Patient Reported Outcomes Measurement Information System (PROMIS) Global physical health scale [ Time Frame: 55 weeks after randomization ]
    Will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding baseline measurement as well as whether or not the patient received radiation therapy which is known to be associated with post-treatment fatigue. No multiple comparisons adjustment will be employed since these outcomes evaluate the toxicity of the investigational drug. The clinical meaningfulness of each comparison will be considered.

  3. Severity of fatigue measured by Patient Reported Outcomes Measurement Information System (PROMIS) fatigue scale [ Time Frame: 55 weeks after randomization ]
    Will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding baseline measurement as well as whether or not the patient received radiation therapy which is known to be associated with post-treatment fatigue. No multiple comparisons adjustment will be employed since these outcomes evaluate the toxicity of the investigational drug. The clinical meaningfulness of each comparison will be considered.


Secondary Outcome Measures :
  1. Distant recurrence-free survival (DRFS) [ Time Frame: From date of randomization to date of invasive distant disease recurrence, second invasive primary cancer (breast or not) or death due to any cause, assessed up to 10 years ]
    The distributions of DRFS will be estimated using the Kaplan-Meier method, with 95% CI calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate.

  2. Emotional function and disease-related symptoms in patients receiving pembrolizumab assessed by Patient Reported Outcomes Measurement Information System (PROMIS) global mental health scale score [ Time Frame: Up to 10 years ]
    Will be compared between the two treatment groups using a mixed model for repeated measures analysis with adjustment for the baseline score and time. Presence of treatment-by-time interaction will be investigated.

  3. Impact of treatment and treatment-related symptoms on physical function in patients without therapy [ Time Frame: 55 weeks after randomization ]
    Compared to patients receiving pembrolizumab. A multiple linear regression model will be performed with physical health scale score as an outcome and treatment and treatment related symptoms as covariates. Presence of treatment by each individual symptom item interactions will be investigated.

  4. Incidence of adverse events assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Up to 10 years ]
    Toxicity analysis will be conducted in all patients receiving at least one dose of MK-3475 (pembrolizumab). The incidence of adverse events will be reported.

  5. Long-term quality of life and symptoms between the two treatment groups [ Time Frame: Up to 60 months after randomization ]
    Mixed models for repeated measures analysis will be used with adjustment for scores at 18 months to examine changes in physical and emotional domain scores, fatigue and other persistent symptoms over the course

  6. Overall survival (OS) [ Time Frame: From date of randomization to date of death due to any cause, assessed up to 10 years ]
    The distributions of OS will be estimated using the Kaplan-Meier method, with 95% CI calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate.

  7. Relationship between treatment-related symptoms and adherence to the study medication [ Time Frame: Up to 10 years ]
    Will be investigated among patients randomized to pembrolizumab treatment group by means of multiple logistic regression. Patients who have been on study therapy for 70% or more of their expected time on therapy will be considered adherent.

  8. Resolution of treatment-related symptoms in patients receiving pembrolizumab [ Time Frame: 18 months after randomization ]
    Compared to patients without treatment. A change in severity of the particular symptom will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding measurement at the 55 week assessment point.

  9. Role of pro-inflammatory cytokines in the development of pembrolizumab associated symptoms [ Time Frame: Up to 55 weeks ]
    Specifically focused on treatment-associated fatigue. This will be compared to patients in the observation group.

  10. Severity and frequency of treatment-related symptoms (diarrhea, nausea, rash, cough, and shortness of breath, musculoskeletal pain) over time of patients receiving pembrolizumab [ Time Frame: Up to 10 years ]
    Compared without treatment. The distributions of the corresponding Patient Reported Outcomes version of Common Terminology Criteria for Adverse Events (PRO-CTCAE) items will be compared between the two treatment groups using a mixed ordinal logistic regression model for repeated measures. The model will also include the corresponding baseline measurement and time. Presence of treatment-by-time interaction will be tested for each of these endpoints. Similar analyses will be performed for disease related symptoms. The descriptive and graphical methods suggested in Basch, et. al. will be used to

  11. Single nucleotide polymorphisms (SNPs) in the promotor region of pro-inflammatory cytokine genes and the risk for development and severity of treatment-associated fatigue and other symptoms [ Time Frame: Up to 10 years ]
    The role of these SNPs in the persistence of long-term fatigue in all patients will also be explored using treatment assignment as a covariate.


Eligibility Criteria

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • STEP 1 REGISTRATION
  • Patients must have histologically confirmed estrogen receptor (ER)-, progesterone receptor (PR)- and HER2-negative (triple-negative, TNBC) with residual invasive breast cancer, as defined by the 2010 and 2013 American Society of Clinical Oncology (ASCO) College of American Pathologists (CAP) guidelines, after completion of neoadjuvant chemotherapy; residual disease must be >= 1 cm in greatest dimension, and/or have positive lymph nodes (ypN+) observed on pathologic exam

    • NOTE: Immunohistochemistry (IHC)-positive isolated tumor cells in the lymph node (N0 [i+]) are not considered node-positive and these patients also must have >= 1 cm residual invasive cancer in the breast in order to be eligible
  • Patients must not have metastatic disease (i.e., must be M0)
  • It is preferred that axillary lymph node sampling is performed after completion of neoadjuvant chemotherapy to allow more accurate assessment of pathologic response; patients must have a complete axillary lymph node dissection after neoadjuvant chemotherapy in the following situations (exceptions will be granted for patients participating in the Alliance A11202 trial):

    • Patients had documented pathologic involvement of the axillary nodes (fine needle aspiration [FNA] or core biopsy) before neoadjuvant chemotherapy and had sentinel node biopsy after neoadjuvant chemotherapy with positive sentinel node(s)
    • Patient had documented pathologic involvement of the axillary nodes (FNA or core biopsy) before neoadjuvant chemotherapy and had only 1 sentinel lymph node removed after neoadjuvant chemotherapy

      • NOTE: Patients who undergo sentinel node biopsy before starting neoadjuvant treatment and do not undergo post neoadjuvant assessment of the axillary nodes or who have negative axillary nodes on post neoadjuvant assessment must have >= 1 cm residual invasive cancer in the breast after completion of neoadjuvant chemotherapy
  • Patients must have a minimum of five, available unstained slides from the residual (post-neoadjuvant) invasive tumor in primary site or lymph node to be submitted within 7 days after registration to determine PD-L1 expression; the tumor tissue must be adequate for PD-L1 testing, which typically requires a minimum of 100 cancer cells per slide
  • Patients must be offered the opportunity to participate in specimen banking
  • Patients must have had neoadjuvant chemotherapy followed by surgery; the recommended neoadjuvant treatment should include 16-24 weeks of a third generation chemotherapy regimen as recommended by National Comprehensive Cancer Network (NCCN) guidelines for triple negative breast cancer (examples include dose dense adriamycin-cytoxan [AC] followed by dose-dense paclitaxel; weekly paclitaxel x 12 followed or preceded by cyclophosphamide-adriamycin-fluorouracil [FAC], fluorouracil-epirubicin-cytoxan [FEC], AC or dose dense AC; docetaxel either followed or preceded by FEC/FAC or AC; carboplatin-containing neoadjuvant chemotherapy is also allowed); patients who cannot complete all planned treatment cycles for any reason are considered high risk and therefore are eligible for the study if they have residual disease; patients must have resolution of adverse event(s) of the most recent prior chemotherapy to grade 1 or less, except alopecia and =< grade 2 neuropathy which are allowed
  • Patients may receive post-operative (adjuvant) chemotherapy for up to 24 weeks of duration (e.g. 8 cycles of capecitabine as in the CREATE-X trial) after completion of surgery at the discretion of the treating physician; patients must have resolution of adverse event(s) of the most recent prior chemotherapy to grade 1 or less, except alopecia and =< grade 2 neuropathy which are allowed; adjuvant chemotherapy, if administered, must have been completed within 35 days prior to screening registration and must be given prior to radiation
  • Patients must have completed their final breast surgery (rendering them free from disease) with clear resection margins for invasive cancer and ductal carcinoma in situ (DCIS) within 90 days prior to screening registration for patients not receiving post-operative (adjuvant) chemotherapy, or within 210 days prior to screening registration for patients who have completed post-operative (adjuvant) chemotherapy; positive margins are allowed only if the surgical team of the patient deems further resection impossible
  • Patients for whom radiation therapy (RT) to the affected breast or chest wall and regional nodal areas is clinically indicated as per NCCN treatment guidelines, should receive RT after randomization when possible, concomitant with MK-3475 (pembrolizumab) if randomized to the experimental arm; however, RT administered prior to registration is also allowed; patients must specify at the time of screening registration whether or not they will receive RT and the extent of intended RT
  • Patients must not have had prior immunotherapy with anti-PD-L1, anti-PD-1, anti-CTLA4 or similar drugs; patients must not be planning to receive any of the prohibited therapies during the screening or treatment phases of the study
  • Patients must not be planning to receive concomitantly other biologic therapy, hormonal therapy, other chemotherapy, surgery or other anti-cancer therapy except radiation therapy while receiving treatment on this protocol
  • Patients must have Zubrod performance status =< 2
  • Patients must not have a history of (non-infectious) pneumonitis that required steroids or evidence of active pneumonitis
  • Patients must not have an active infection requiring systemic therapy
  • Patients must not have active autoimmune disease that has required systemic treatment in past 2 years (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs); replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment
  • Patients must not have received live vaccines within 30 days prior to registration; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, shingles, yellow fever, rabies, Bacillus Calmette-Guerin (BCG), and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines, and are not allowed
  • Patients must not have known active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection prior to registration; patients who have completed curative therapy for HCV are eligible; patients with known human immunodeficiency virus (HIV) infection are eligible if they meet each of the following 3 criteria:

    • CD4 counts >= 350 mm^3
    • Serum HIV viral load of < 25,000 IU/ml and
    • Treated on a stable antiretroviral regimen
  • No other prior invasive malignancy is allowed except for the following: adequately treated basal (or squamous cell) skin cancer, in situ breast or cervical cancer; stage I or II invasive cancer treated with a curative intent without evidence of disease recurrence for at least five years
  • Patients must be informed of the investigational nature of this study and must sign and give written informed consent for this protocol in accordance with institutional and federal guidelines
  • As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
  • STEP 2 REGISTRATION
  • Patients must not be registered to step 2 until receiving confirmation from the Southwest Oncology Group (SWOG) Statistical Center that the patient's tissue specimen was adequate for PD-L1 testing; patients must be registered within 7 days of receiving the e-mail notification confirming submission was evaluable for PD-L1 status
  • A serum thyroid-stimulating hormone (TSH) must be obtained within 28 days prior to step 2 registration to obtain a baseline value
  • Absolute neutrophil count (ANC) >= 1,500 microliter (mcL)
  • Platelets >= 100,000/mcL
  • Hemoglobin >= 9 g/dL
  • Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except Gilbert's syndrome, who must have a total bilirubin < 3.0 mg/dL)
  • Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) or serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 2.5 x IULN
  • Alkaline phosphatase =< 2.5 x IULN
  • Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min
  • Women of childbearing potential must have a negative urine or serum pregnancy test within 28 day prior to registration; women/men of reproductive potential must have agreed to use an effective contraceptive method for the course of the study through 120 days after the last dose of study medication; should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy, bilateral tubal ligation, or vasectomy; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures; patients must not be pregnant or nursing
  • Site must verify that there is no known change in the step 1 eligibility since initial registration
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02954874


  Hide Study Locations
Locations
United States, Alabama
Southern Cancer Center PC-Daphne Recruiting
Daphne, Alabama, United States, 36526
Contact: Connie D. Uzel    251-607-5281    sue.deoliveira@southerncancercenter.com   
Principal Investigator: Connie D. Uzel         
Southern Cancer Center PC-Mobile Recruiting
Mobile, Alabama, United States, 36607
Contact: Connie D. Uzel    251-607-5281    sue.deoliveira@southerncancercenter.com   
Principal Investigator: Connie D. Uzel         
Southern Cancer Center PC-Providence Recruiting
Mobile, Alabama, United States, 36608
Contact: Connie D. Uzel    251-607-5281    sue.deoliveira@southerncancercenter.com   
Principal Investigator: Connie D. Uzel         
Southern Cancer Center PC-Springhill Recruiting
Mobile, Alabama, United States, 36608
Contact: Connie D. Uzel    251-607-5281    sue.deoliveira@southerncancercenter.com   
Principal Investigator: Connie D. Uzel         
United States, Alaska
Alaska Oncology and Hematology LLC Recruiting
Anchorage, Alaska, United States, 99508
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Anchorage Oncology Centre Recruiting
Anchorage, Alaska, United States, 99508
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Katmai Oncology Group Recruiting
Anchorage, Alaska, United States, 99508
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Providence Alaska Medical Center Recruiting
Anchorage, Alaska, United States, 99508
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Fairbanks Memorial Hospital Recruiting
Fairbanks, Alaska, United States, 99701
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
United States, Arizona
University of Arizona Cancer Center-North Campus Recruiting
Tucson, Arizona, United States, 85719
Contact: Simran K. Sindhu    520-626-9008      
Principal Investigator: Simran K. Sindhu         
The University of Arizona Medical Center-University Campus Recruiting
Tucson, Arizona, United States, 85724
Contact: Simran K. Sindhu    520-626-9008      
Principal Investigator: Simran K. Sindhu         
United States, Arkansas
Highlands Oncology Group-Rogers Recruiting
Rogers, Arkansas, United States, 72758
Contact: Joseph T. Beck    800-381-6939      
Principal Investigator: Joseph T. Beck         
United States, California
Kaiser Permanente-Anaheim Recruiting
Anaheim, California, United States, 92807
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-Deer Valley Medical Center Recruiting
Antioch, California, United States, 94531
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Sutter Auburn Faith Hospital Recruiting
Auburn, California, United States, 95602
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
AIS Cancer Center at San Joaquin Community Hospital Recruiting
Bakersfield, California, United States, 93301
Contact: Helen K. Chew    916-734-3089      
Principal Investigator: Helen K. Chew         
Kaiser Permanente-Baldwin Park Recruiting
Baldwin Park, California, United States, 91706
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-Bellflower Recruiting
Bellflower, California, United States, 90706
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Alta Bates Summit Medical Center-Herrick Campus Recruiting
Berkeley, California, United States, 94704
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Mills-Peninsula Medical Center Recruiting
Burlingame, California, United States, 94010
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
City of Hope Corona Recruiting
Corona, California, United States, 92879
Contact: Joanne E. Mortimer    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Joanne E. Mortimer         
City of Hope Comprehensive Cancer Center Recruiting
Duarte, California, United States, 91010
Contact: Joanne E. Mortimer    800-826-4673    becomingapatient@coh.org   
Principal Investigator: Joanne E. Mortimer         
Epic Care-Dublin Recruiting
Dublin, California, United States, 94568
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Bay Area Breast Surgeons Inc Recruiting
Emeryville, California, United States, 94608
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Epic Care Partners in Cancer Care Recruiting
Emeryville, California, United States, 94608
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Kaiser Permanente Hospital Recruiting
Fontana, California, United States, 92335
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-Fremont Recruiting
Fremont, California, United States, 94538
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente Recruiting
Fresno, California, United States, 93720
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Saint Jude Medical Center Recruiting
Fullerton, California, United States, 92835
Contact: William E. Lawler    714-446-5642      
Principal Investigator: William E. Lawler         
Kaiser Permanente - Harbor City Recruiting
Harbor City, California, United States, 90710
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-Irvine Recruiting
Irvine, California, United States, 92618
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente Los Angeles Medical Center Recruiting
Los Angeles, California, United States, 90027
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Los Angeles County-USC Medical Center Recruiting
Los Angeles, California, United States, 90033
Contact: Min J. Lu    323-865-0451      
Principal Investigator: Min J. Lu         
USC / Norris Comprehensive Cancer Center Recruiting
Los Angeles, California, United States, 90033
Contact: Min J. Lu    323-865-0451      
Principal Investigator: Min J. Lu         
Kaiser Permanente-Cadillac Recruiting
Los Angeles, California, United States, 90034
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Contra Costa Regional Medical Center Recruiting
Martinez, California, United States, 94553-3156
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Fremont - Rideout Cancer Center Recruiting
Marysville, California, United States, 95901
Contact: Helen K. Chew    916-734-3089      
Principal Investigator: Helen K. Chew         
Memorial Medical Center Recruiting
Modesto, California, United States, 95355
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Kaiser Permanente-Modesto Recruiting
Modesto, California, United States, 95356
Contact: Louis Fehrenbacher    877-642-4691      
Principal Investigator: Louis Fehrenbacher         
Palo Alto Medical Foundation-Camino Division Recruiting
Mountain View, California, United States, 94040
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Palo Alto Medical Foundation-Gynecologic Oncology Recruiting
Mountain View, California, United States, 94040
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
USC Norris Oncology/Hematology-Newport Beach Recruiting
Newport Beach, California, United States, 92663
Contact: Min J. Lu    323-865-0451      
Principal Investigator: Min J. Lu         
Sutter Cancer Research Consortium Recruiting
Novato, California, United States, 94945
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Alta Bates Summit Medical Center - Summit Campus Recruiting
Oakland, California, United States, 94609
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Bay Area Tumor Institute Recruiting
Oakland, California, United States, 94609
Contact: James H. Feusner       protocols@swog.org   
Principal Investigator: James H. Feusner         
Kaiser Permanente-Oakland Recruiting
Oakland, California, United States, 94611
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Ontario Recruiting
Ontario, California, United States, 91761
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Saint Joseph Hospital - Orange Recruiting
Orange, California, United States, 92868
Contact: Timothy E. Byun    714-734-6220      
Principal Investigator: Timothy E. Byun         
UC Irvine Health/Chao Family Comprehensive Cancer Center Recruiting
Orange, California, United States, 92868
Contact: Rita S. Mehta    877-827-8839    ucstudy@uci.edu   
Principal Investigator: Rita S. Mehta         
Palo Alto Medical Foundation Health Care Recruiting
Palo Alto, California, United States, 94301
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Stanford Cancer Institute Palo Alto Recruiting
Palo Alto, California, United States, 94304
Contact: Melinda L. Telli    650-498-7061    ccto-office@stanford.edu   
Principal Investigator: Melinda L. Telli         
Kaiser Permanente - Panorama City Recruiting
Panorama City, California, United States, 91402
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Huntington Memorial Hospital Recruiting
Pasadena, California, United States, 91105
Contact: Steven H. Applebaum    626-535-2420      
Principal Investigator: Steven H. Applebaum         
Kaiser Permanente-Redwood City Recruiting
Redwood City, California, United States, 94063
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Richmond Recruiting
Richmond, California, United States, 94801
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Riverside Recruiting
Riverside, California, United States, 92505
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-Roseville Recruiting
Roseville, California, United States, 95661
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Sutter Roseville Medical Center Recruiting
Roseville, California, United States, 95661
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Sutter Medical Center Sacramento Recruiting
Sacramento, California, United States, 95816
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
University of California Davis Comprehensive Cancer Center Recruiting
Sacramento, California, United States, 95817
Contact: Helen K. Chew    916-734-3089      
Principal Investigator: Helen K. Chew         
Kaiser Permanente - Sacramento Recruiting
Sacramento, California, United States, 95825
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-San Diego Mission Recruiting
San Diego, California, United States, 92108
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente-San Diego Zion Recruiting
San Diego, California, United States, 92120
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
California Pacific Medical Center-Pacific Campus Recruiting
San Francisco, California, United States, 94115
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Kaiser Permanente-San Francisco Recruiting
San Francisco, California, United States, 94115
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Santa Teresa-San Jose Recruiting
San Jose, California, United States, 95119
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Stanford Cancer Center South Bay Recruiting
San Jose, California, United States, 95124
Contact: Melinda L. Telli    650-498-7061    ccto-office@stanford.edu   
Principal Investigator: Melinda L. Telli         
Kaiser Permanente San Leandro Recruiting
San Leandro, California, United States, 94577
Contact: Louis Fehrenbacher    510-454-2724      
Principal Investigator: Louis Fehrenbacher         
Pacific Central Coast Health Center-San Luis Obispo Recruiting
San Luis Obispo, California, United States, 93401
Contact: Brian A. DiCarlo       Diane.DeVos-Schmidt@DignityHealth.org   
Principal Investigator: Brian A. DiCarlo         
Kaiser Permanente-San Marcos Recruiting
San Marcos, California, United States, 92069
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
Kaiser Permanente Medical Center - Santa Clara Recruiting
Santa Clara, California, United States, 95051
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Palo Alto Medical Foundation-Santa Cruz Recruiting
Santa Cruz, California, United States, 95065
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Kaiser Permanente-Santa Rosa Recruiting
Santa Rosa, California, United States, 95403
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-South San Francisco Recruiting
South San Francisco, California, United States, 94080
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Stockton Recruiting
Stockton, California, United States, 95210
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Palo Alto Medical Foundation-Sunnyvale Recruiting
Sunnyvale, California, United States, 94086
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Gene Upshaw Memorial Tahoe Forest Cancer Center Recruiting
Truckee, California, United States, 96161
Contact: Helen K. Chew    916-734-3089      
Principal Investigator: Helen K. Chew         
Kaiser Permanente Medical Center-Vacaville Recruiting
Vacaville, California, United States, 95688
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente-Vallejo Recruiting
Vallejo, California, United States, 94589
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Sutter Solano Medical Center/Cancer Center Recruiting
Vallejo, California, United States, 94589
Contact: Ari D. Baron    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Ari D. Baron         
Kaiser Permanente-Walnut Creek Recruiting
Walnut Creek, California, United States, 94596
Contact: Louis Fehrenbacher    510-891-3400      
Principal Investigator: Louis Fehrenbacher         
Kaiser Permanente Recruiting
Woodland Hills, California, United States, 91367
Contact: Jonathan A. Polikoff    626-564-3455      
Principal Investigator: Jonathan A. Polikoff         
United States, Colorado
University of Colorado Hospital Recruiting
Aurora, Colorado, United States, 80045
Contact: Anthony D. Elias    720-848-0650      
Principal Investigator: Anthony D. Elias         
Rocky Mountain Cancer Centers-Boulder Recruiting
Boulder, Colorado, United States, 80304
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Penrose-Saint Francis Healthcare Recruiting
Colorado Springs, Colorado, United States, 80907
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Memorial Hospital Central Recruiting
Colorado Springs, Colorado, United States, 80909
Contact: Anthony D. Elias    719-365-2406      
Principal Investigator: Anthony D. Elias         
Kaiser Permanente-Franklin Recruiting
Denver, Colorado, United States, 80205
Contact: Alexander Menter    303-614-1300      
Principal Investigator: Alexander Menter         
Porter Adventist Hospital Recruiting
Denver, Colorado, United States, 80210
Contact: Mehmet S. Copur    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Mehmet S. Copur         
Comprehensive Cancer Care and Research Institute of Colorado LLC Recruiting
Englewood, Colorado, United States, 80113
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Poudre Valley Hospital Recruiting
Fort Collins, Colorado, United States, 80524
Contact: Anthony D. Elias    970-297-6150      
Principal Investigator: Anthony D. Elias         
National Jewish Health-Western Hematology Oncology Recruiting
Golden, Colorado, United States, 80401
Contact: Keren Sturtz    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
North Colorado Medical Center Recruiting
Greeley, Colorado, United States, 80631
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Kaiser Permanente-Rock Creek Recruiting
Lafayette, Colorado, United States, 80026
Contact: Alexander Menter    303-614-1300      
Principal Investigator: Alexander Menter         
Saint Anthony Hospital Recruiting
Lakewood, Colorado, United States, 80228
Contact: Mehmet S. Copur    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Mehmet S. Copur         
Littleton Adventist Hospital Recruiting
Littleton, Colorado, United States, 80122
Contact: Mehmet S. Copur    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Mehmet S. Copur         
Kaiser Permanente-Lone Tree Recruiting
Lone Tree, Colorado, United States, 80124
Contact: Alexander Menter    303-614-1300      
Principal Investigator: Alexander Menter         
Longmont United Hospital Recruiting
Longmont, Colorado, United States, 80501
Contact: Mehmet S. Copur    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Mehmet S. Copur         
McKee Medical Center Recruiting
Loveland, Colorado, United States, 80539
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Parker Adventist Hospital Recruiting
Parker, Colorado, United States, 80138
Contact: Mehmet S. Copur    303-777-2663    kgeisen@co-cancerresearch.org   
Principal Investigator: Mehmet S. Copur         
United States, Connecticut
Smilow Cancer Hospital-Derby Care Center Recruiting
Derby, Connecticut, United States, 06418
Contact: Lajos Pusztai    855-476-4569      
Principal Investigator: Lajos Pusztai         
Greenwich Hospital Recruiting
Greenwich, Connecticut, United States, 06830
Contact: Beverly J. Drucker    203-863-3698      
Principal Investigator: Beverly J. Drucker         
Smilow Cancer Hospital Care Center at Saint Francis Recruiting
Hartford, Connecticut, United States, 06105
Contact: Lajos Pusztai    860-714-4680      
Principal Investigator: Lajos Pusztai         
Smilow Cancer Center/Yale-New Haven Hospital Recruiting
New Haven, Connecticut, United States, 06510
Contact: Lajos Pusztai    855-476-4569      
Principal Investigator: Lajos Pusztai         
Yale University Recruiting
New Haven, Connecticut, United States, 06520
Contact: Lajos Pusztai    203-785-5702      
Principal Investigator: Lajos Pusztai         
Yale-New Haven Hospital North Haven Medical Center Recruiting
North Haven, Connecticut, United States, 06473
Contact: Lajos Pusztai    877-978-8343      
Principal Investigator: Lajos Pusztai         
Smilow Cancer Hospital-Orange Care Center Recruiting
Orange, Connecticut, United States, 06477
Contact: Lajos Pusztai    855-476-4569      
Principal Investigator: Lajos Pusztai         
Charlotte Hungerford Hospital Center for Cancer Care Recruiting
Torrington, Connecticut, United States, 06790
Contact: Lajos Pusztai    860-482-5384      
Principal Investigator: Lajos Pusztai         
Smilow Cancer Hospital Care Center-Trumbull Recruiting
Trumbull, Connecticut, United States, 06611
Contact: Lajos Pusztai    855-476-4569      
Principal Investigator: Lajos Pusztai         
Smilow Cancer Hospital-Waterbury Care Center Recruiting
Waterbury, Connecticut, United States, 06708
Contact: Lajos Pusztai    855-476-4569      
Principal Investigator: Lajos Pusztai         
United States, Delaware
Helen F Graham Cancer Center Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Medical Oncology Hematology Consultants PA Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Gregory A. Masters         
Beebe Health Campus Recruiting
Rehoboth Beach, Delaware, United States, 19971
Contact: Gregory A. Masters    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Gregory A. Masters         
Nanticoke Memorial Hospital Recruiting
Seaford, Delaware, United States, 19973
Contact: Gregory A. Masters    302-628-6344      
Principal Investigator: Gregory A. Masters         
United States, District of Columbia
Sibley Memorial Hospital Recruiting
Washington, District of Columbia, United States, 20016
Contact: Danijela Jelovac    410-955-8804    jhcccro@jhmi.edu   
Principal Investigator: Danijela Jelovac         
United States, Florida
UF Cancer Center at Orlando Health Recruiting
Orlando, Florida, United States, 32806
Contact: Regan D. Rostorfer    321-841-7246    CancerClinicalTrials@orlandohealth.com   
Principal Investigator: Regan D. Rostorfer         
Sacred Heart Hospital Recruiting
Pensacola, Florida, United States, 32504
Contact: Ranjith B. Dissanayake    850-416-4611    ttamayo@shhpens.org   
Principal Investigator: Ranjith B. Dissanayake         
United States, Georgia
Northside Hospital Recruiting
Atlanta, Georgia, United States, 30342
Contact: Amelia B. Zelnak    404-778-1868      
Principal Investigator: Amelia B. Zelnak         
Dekalb Medical Center Recruiting
Decatur, Georgia, United States, 30033
Contact: Sharad A. Ghamande    706-721-1663    cancer@augusta.edu   
Principal Investigator: Sharad A. Ghamande         
Gwinnett Medical Center Recruiting
Lawrenceville, Georgia, United States, 30045
Contact: Aldemar Montero    678-312-2666      
Principal Investigator: Aldemar Montero         
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Recruiting
Savannah, Georgia, United States, 31405
Contact: Howard A. Zaren    912-819-5704      
Principal Investigator: Howard A. Zaren         
South Georgia Medical Center/Pearlman Cancer Center Recruiting
Valdosta, Georgia, United States, 31602
Contact: Samuel N. Ofori    229-259-4628    maryann.heddon@sgmc.org   
Principal Investigator: Samuel N. Ofori         
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Recruiting
Boise, Idaho, United States, 83706
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Saint Alphonsus Cancer Care Center-Caldwell Recruiting
Caldwell, Idaho, United States, 83605
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Walter Knox Memorial Hospital Recruiting
Emmett, Idaho, United States, 83617
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Idaho Urologic Institute-Meridian Recruiting
Meridian, Idaho, United States, 83642
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Saint Alphonsus Medical Center-Nampa Recruiting
Nampa, Idaho, United States, 83686
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
United States, Illinois
Mac Neal Hospital Recruiting
Berwyn, Illinois, United States, 60402
Contact: Irene Q. Ma    708-783-0966      
Principal Investigator: Irene Q. Ma         
Illinois CancerCare-Bloomington Recruiting
Bloomington, Illinois, United States, 61704
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Canton Recruiting
Canton, Illinois, United States, 61520
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Carthage Recruiting
Carthage, Illinois, United States, 62321
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Centralia Oncology Clinic Recruiting
Centralia, Illinois, United States, 62801
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Mount Sinai Hospital Medical Center Recruiting
Chicago, Illinois, United States, 60608
Contact: Pam G. Khosla    773-257-5960    suhi@sinai.org   
Principal Investigator: Pam G. Khosla         
Northwestern University Recruiting
Chicago, Illinois, United States, 60611
Contact: William J. Gradishar    312-695-1301    cancer@northwestern.edu   
Principal Investigator: William J. Gradishar         
Rush University Medical Center Recruiting
Chicago, Illinois, United States, 60612
Contact: Melody A. Cobleigh    312-942-5498    clinical_trials@rush.edu   
Principal Investigator: Melody A. Cobleigh         
University of Chicago Comprehensive Cancer Center Recruiting
Chicago, Illinois, United States, 60637
Contact: Rita Nanda    773-834-7424      
Principal Investigator: Rita Nanda         
Weiss Memorial Hospital Recruiting
Chicago, Illinois, United States, 60640
Contact: Stuart A. Krauss    773-564-5032      
Principal Investigator: Stuart A. Krauss         
Cancer Care Center of Decatur Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Crossroads Cancer Center Recruiting
Effingham, Illinois, United States, 62401
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Eureka Recruiting
Eureka, Illinois, United States, 61530
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Galesburg Recruiting
Galesburg, Illinois, United States, 61401
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Northwestern Medicine Cancer Center Delnor Recruiting
Geneva, Illinois, United States, 60134
Contact: John D. Ayers    847-827-9060      
Principal Investigator: John D. Ayers         
Illinois CancerCare-Kewanee Clinic Recruiting
Kewanee, Illinois, United States, 61443
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Northwestern Medicine Lake Forest Hospital Recruiting
Lake Forest, Illinois, United States, 60045
Contact: William J. Gradishar    312-695-1301    cancer@northwestern.edu   
Principal Investigator: William J. Gradishar         
Illinois CancerCare-Macomb Recruiting
Macomb, Illinois, United States, 61455
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Loyola University Medical Center Recruiting
Maywood, Illinois, United States, 60153
Contact: Kathy S. Albain    708-226-4357      
Principal Investigator: Kathy S. Albain         
Illinois CancerCare-Ottawa Clinic Recruiting
Ottawa, Illinois, United States, 61350
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Pekin Recruiting
Pekin, Illinois, United States, 61554
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Peru Recruiting
Peru, Illinois, United States, 61354
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Princeton Recruiting
Princeton, Illinois, United States, 61356
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
West Suburban Medical Center Recruiting
River Forest, Illinois, United States, 60305
Contact: Irene Q. Ma    708-763-2707      
Principal Investigator: Irene Q. Ma         
SwedishAmerican Regional Cancer Center/ACT Recruiting
Rockford, Illinois, United States, 61114
Contact: Harvey E. Einhorn    779-696-9400    cancercare@swedishamerican.org   
Principal Investigator: Harvey E. Einhorn         
Southern Illinois University School of Medicine Recruiting
Springfield, Illinois, United States, 62702
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Springfield Clinic Recruiting
Springfield, Illinois, United States, 62702
Contact: James L. Wade    800-444-7541      
Principal Investigator: James L. Wade         
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Cancer Care Specialists of Illinois-Swansea Recruiting
Swansea, Illinois, United States, 62226
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Northwestern Medicine Cancer Center Warrenville Recruiting
Warrenville, Illinois, United States, 60555
Contact: John D. Ayers    847-827-9060      
Principal Investigator: John D. Ayers         
United States, Indiana
Deaconess Clinic Downtown Recruiting
Evansville, Indiana, United States, 47713
Contact: Kendrith M. Rowland    877-654-0311      
Principal Investigator: Kendrith M. Rowland         
Memorial Regional Cancer Center Day Road Recruiting
Mishawaka, Indiana, United States, 46545
Contact: Thomas J. Reid    800-284-7370      
Principal Investigator: Thomas J. Reid         
Chancellor Center for Oncology Recruiting
Newburgh, Indiana, United States, 47630
Contact: Kendrith M. Rowland    812-426-9576      
Principal Investigator: Kendrith M. Rowland         
Memorial Hospital of South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Thomas J. Reid    800-284-7370      
Principal Investigator: Thomas J. Reid         
United States, Iowa
Mary Greeley Medical Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
McFarland Clinic PC-William R Bliss Cancer Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
McFarland Clinic PC-Boone Recruiting
Boone, Iowa, United States, 50036
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Greater Regional Medical Center Recruiting
Creston, Iowa, United States, 50801
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Genesis Medical Center - East Campus Recruiting
Davenport, Iowa, United States, 52803
Contact: George Kovach    800-446-6088    werners@genesishealth.com   
Principal Investigator: George Kovach         
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    515-239-2621      
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Des Moines Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    515-239-2621      
Principal Investigator: Robert J. Behrens         
Broadlawns Medical Center Recruiting
Des Moines, Iowa, United States, 50314
Contact: Robert J. Behrens    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Mercy Medical Center - Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Iowa Lutheran Hospital Recruiting
Des Moines, Iowa, United States, 50316
Contact: Robert J. Behrens    515-241-8704      
Principal Investigator: Robert J. Behrens         
McFarland Clinic PC-Trinity Cancer Center Recruiting
Fort Dodge, Iowa, United States, 50501
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
McFarland Clinic PC-Jefferson Recruiting
Jefferson, Iowa, United States, 50129
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
McFarland Clinic PC-Marshalltown Recruiting
Marshalltown, Iowa, United States, 50158
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Methodist West Hospital Recruiting
West Des Moines, Iowa, United States, 50266-7700
Contact: Robert J. Behrens    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Robert J. Behrens         
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
United States, Kansas
Cancer Center of Kansas - Chanute Recruiting
Chanute, Kansas, United States, 66720
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Dodge City Recruiting
Dodge City, Kansas, United States, 67801
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Fort Scott Recruiting
Fort Scott, Kansas, United States, 66701
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
University of Kansas Cancer Center Recruiting
Kansas City, Kansas, United States, 66160
Contact: Joshua M. Mammen    913-945-7552    ctnursenav@kumc.edu   
Principal Investigator: Joshua M. Mammen         
Cancer Center of Kansas-Kingman Recruiting
Kingman, Kansas, United States, 67068
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Liberal Recruiting
Liberal, Kansas, United States, 67905
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - McPherson Recruiting
McPherson, Kansas, United States, 67460
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Newton Recruiting
Newton, Kansas, United States, 67114
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Parsons Recruiting
Parsons, Kansas, United States, 67357
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Pratt Recruiting
Pratt, Kansas, United States, 67124
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Wellington Recruiting
Wellington, Kansas, United States, 67152
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
University of Kansas Hospital-Westwood Cancer Center Recruiting
Westwood, Kansas, United States, 66205
Contact: Joshua M. Mammen    913-945-7552    ctnursenav@kumc.edu   
Principal Investigator: Joshua M. Mammen         
Cancer Center of Kansas-Wichita Medical Arts Tower Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Wichita Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Via Christi Regional Medical Center Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Winfield Recruiting
Winfield, Kansas, United States, 67156
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
United States, Kentucky
Saint Joseph Hospital East Recruiting
Lexington, Kentucky, United States, 40509
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
University of Kentucky/Markey Cancer Center Recruiting
Lexington, Kentucky, United States, 40536
Contact: Mara D. Chambers    859-257-3379      
Principal Investigator: Mara D. Chambers         
United States, Louisiana
Christus Saint Frances Cabrini Hospital Recruiting
Alexandria, Louisiana, United States, 71301
Contact: John T. Cole    504-842-3708      
Principal Investigator: John T. Cole         
LSU Health Baton Rouge-North Clinic Recruiting
Baton Rouge, Louisiana, United States, 70805
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Hematology/Oncology Clinic LLP Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: Hana F. Safah    504-988-6121      
Principal Investigator: Hana F. Safah         
Louisiana Hematology Oncology Associates LLC Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Mary Bird Perkins Cancer Center Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Medical Oncology LLC Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Ochsner Health Center-Summa Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: John T. Cole    504-842-3708      
Principal Investigator: John T. Cole         
North Shore Hematology Oncology Associates Inc Recruiting
Covington, Louisiana, United States, 70433
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Oncology Center of The South Incorporated Recruiting
Houma, Louisiana, United States, 70360
Contact: David S. Hanson    225-215-1353    clinicalresearch@marybird.com   
Principal Investigator: David S. Hanson         
Ochsner Medical Center Kenner Recruiting
Kenner, Louisiana, United States, 70065
Contact: John T. Cole    504-842-3708      
Principal Investigator: John T. Cole         
CHRISTUS Saint Patrick Hospital Recruiting
Lake Charles, Louisiana, United States, 70601
Contact: John T. Cole    504-842-3708      
Principal Investigator: John T. Cole         
Ochsner Medical Center Jefferson Recruiting
New Orleans, Louisiana, United States, 70121
Contact: John T. Cole    504-842-3708      
Principal Investigator: John T. Cole         
United States, Maine
York Hospital Recruiting
York, Maine, United States, 03909
Contact: Marilyn A. McLaughlin    207-351-3777      
Principal Investigator: Marilyn A. McLaughlin         
United States, Maryland
Mercy Medical Center Recruiting
Baltimore, Maryland, United States, 21202
Contact: David A. Riseberg    410-951-7950    prc@mdmercy.com   
Principal Investigator: David A. Riseberg         
Greater Baltimore Medical Center Recruiting
Baltimore, Maryland, United States, 21204
Contact: Robert B. Donegan    443-849-3706      
Principal Investigator: Robert B. Donegan         
Saint Agnes Hospital Recruiting
Baltimore, Maryland, United States, 21229
Contact: Diana H. Griffiths    410-368-2910      
Principal Investigator: Diana H. Griffiths         
Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting
Baltimore, Maryland, United States, 21287
Contact: Danijela Jelovac    410-955-8804    jhcccro@jhmi.edu   
Principal Investigator: Danijela Jelovac         
Frederick Memorial Hospital Recruiting
Frederick, Maryland, United States, 21701
Contact: Brian M. O'Connor    240-566-3584    clinicaltrials@fmh.org   
Principal Investigator: Brian M. O'Connor         
United States, Massachusetts
Boston Medical Center Recruiting
Boston, Massachusetts, United States, 02118
Contact: Lauren J. Oshry    617-638-8265      
Principal Investigator: Lauren J. Oshry         
Lahey Hospital and Medical Center Recruiting
Burlington, Massachusetts, United States, 01805
Contact: Corrine L. Zarwan    781-744-8027      
Principal Investigator: Corrine L. Zarwan         
Lowell General Hospital Recruiting
Lowell, Massachusetts, United States, 01854
Contact: Richard M. Zuniga    978-788-7084    ghincks@lowellgeneral.org   
Principal Investigator: Richard M. Zuniga         
United States, Michigan
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
University of Michigan Comprehensive Cancer Center Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Anne F. Schott    800-865-1125      
Principal Investigator: Anne F. Schott         
Bronson Battle Creek Recruiting
Battle Creek, Michigan, United States, 49017
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
IHA Hematology Oncology Consultants-Brighton Recruiting
Brighton, Michigan, United States, 48114
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Henry Ford Cancer Institute¿Downriver Recruiting
Brownstown, Michigan, United States, 48183
Contact: Ding Wang    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Ding Wang         
Caro Cancer Center Recruiting
Caro, Michigan, United States, 48723
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
IHA Hematology Oncology Consultants-Chelsea Recruiting
Chelsea, Michigan, United States, 48118
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Hematology Oncology Consultants-Clarkston Recruiting
Clarkston, Michigan, United States, 48346
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Newland Medical Associates-Clarkston Recruiting
Clarkston, Michigan, United States, 48346
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Henry Ford Macomb Hospital-Clinton Township Recruiting
Clinton Township, Michigan, United States, 48038
Contact: Ding Wang    313-916-1784      
Principal Investigator: Ding Wang         
Henry Ford Medical Center-Fairlane Recruiting
Dearborn, Michigan, United States, 48126
Contact: Ding Wang    888-734-5322      
Principal Investigator: Ding Wang         
Henry Ford Hospital Recruiting
Detroit, Michigan, United States, 48202
Contact: Ding Wang    313-916-1784      
Principal Investigator: Ding Wang         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Michigan State University Clinical Center Recruiting
East Lansing, Michigan, United States, 48824-7016
Contact: Deimante M. Tamkus    517-975-9547      
Principal Investigator: Deimante M. Tamkus         
Genesee Cancer and Blood Disease Treatment Center Recruiting
Flint, Michigan, United States, 48503
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Genesee Hematology Oncology PC Recruiting
Flint, Michigan, United States, 48503
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48503
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Mercy Health Saint Mary's Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Kathleen J. Yost       protocols@swog.org   
Principal Investigator: Kathleen J. Yost         
Spectrum Health at Butterworth Campus Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center Recruiting
Grosse Pointe Woods, Michigan, United States, 48236
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Great Lakes Cancer Management Specialists-Macomb Medical Campus Recruiting
Macomb, Michigan, United States, 48044
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Saint Mary's Oncology/Hematology Associates of Marlette Recruiting
Marlette, Michigan, United States, 48453
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Mid-Michigan Medical Center - Midland Recruiting
Midland, Michigan, United States, 48670
Contact: Michel R. Hurtubise    989-839-3377      
Principal Investigator: Michel R. Hurtubise         
Monroe Cancer Center Recruiting
Monroe, Michigan, United States, 48162
Contact: Abhijit B. Saste    419-824-1842      
Principal Investigator: Abhijit B. Saste         
Mercy Health Mercy Campus Recruiting
Muskegon, Michigan, United States, 49444
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Assarian Cancer Center Recruiting
Novi, Michigan, United States, 48374-1236
Contact: Cynthia M. Vakhariya    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Cynthia M. Vakhariya         
Henry Ford Medical Center-Columbus Recruiting
Novi, Michigan, United States, 48377
Contact: Ding Wang    888-734-5322      
Principal Investigator: Ding Wang         
21st Century Oncology-Pontiac Recruiting
Pontiac, Michigan, United States, 48341
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Hope Cancer Center Recruiting
Pontiac, Michigan, United States, 48341
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Newland Medical Associates-Pontiac Recruiting
Pontiac, Michigan, United States, 48341
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Spectrum Health Reed City Hospital Recruiting
Reed City, Michigan, United States, 49677
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Oncology Hematology Associates of Saginaw Valley PC Recruiting
Saginaw, Michigan, United States, 48604
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Marie Yeager Cancer Center Recruiting
Saint Joseph, Michigan, United States, 49085
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Providence Hospital-Southfield Cancer Center Recruiting
Southfield, Michigan, United States, 48075
Contact: Cynthia M. Vakhariya    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Cynthia M. Vakhariya         
Munson Medical Center Recruiting
Traverse City, Michigan, United States, 49684
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Great Lakes Cancer Management Specialists-Macomb Professional Building Recruiting
Warren, Michigan, United States, 48093
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Henry Ford West Bloomfield Hospital Recruiting
West Bloomfield, Michigan, United States, 48322
Contact: Ding Wang    888-734-5322      
Principal Investigator: Ding Wang         
Saint Mary's Oncology/Hematology Associates of West Branch Recruiting
West Branch, Michigan, United States, 48661
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
Metro Health Hospital Recruiting
Wyoming, Michigan, United States, 49519
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
IHA Hematology Oncology Consultants-Ann Arbor Recruiting
Ypsilanti, Michigan, United States, 48197
Contact: Christopher M. Reynolds    208-367-7954      
Principal Investigator: Christopher M. Reynolds         
United States, Minnesota
Sanford Clinic North-Bemidgi Recruiting
Bemidji, Minnesota, United States, 56601
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Fairview Ridges Hospital Recruiting
Burnsville, Minnesota, United States, 55337
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Essentia Health Cancer Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Bret E. Friday    888-203-7267      
Principal Investigator: Bret E. Friday         
Essentia Health Saint Mary's Medical Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Bret E. Friday    888-203-7267      
Principal Investigator: Bret E. Friday         
Miller-Dwan Hospital Recruiting
Duluth, Minnesota, United States, 55805
Contact: Bret E. Friday    888-203-7267      
Principal Investigator: Bret E. Friday         
Fairview-Southdale Hospital Recruiting
Edina, Minnesota, United States, 55435
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Unity Hospital Recruiting
Fridley, Minnesota, United States, 55432
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Fairview Maple Grove Medical Center Recruiting
Maple Grove, Minnesota, United States, 55369
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Minnesota Oncology Hematology PA-Maplewood Recruiting
Maplewood, Minnesota, United States, 55109
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Saint John's Hospital - Healtheast Recruiting
Maplewood, Minnesota, United States, 55109
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Health Partners Inc Recruiting
Minneapolis, Minnesota, United States, 55454
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
New Ulm Medical Center Recruiting
New Ulm, Minnesota, United States, 56073
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
North Memorial Medical Health Center Recruiting
Robbinsdale, Minnesota, United States, 55422
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Coborn Cancer Center at Saint Cloud Hospital Recruiting
Saint Cloud, Minnesota, United States, 56303
Contact: Donald J. Jurgens    877-229-4907    coborncancercenter@centracare.com   
Principal Investigator: Donald J. Jurgens         
Park Nicollet Clinic - Saint Louis Park Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Saint Francis Regional Medical Center Recruiting
Shakopee, Minnesota, United States, 55379
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Lakeview Hospital Recruiting
Stillwater, Minnesota, United States, 55082
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Ridgeview Medical Center Recruiting
Waconia, Minnesota, United States, 55387
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Minnesota Oncology Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
Fairview Lakes Medical Center Recruiting
Wyoming, Minnesota, United States, 55092
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
United States, Mississippi
Singing River Hospital Recruiting
Pascagoula, Mississippi, United States, 39581
Contact: James E. Clarkson    228-809-5292      
Principal Investigator: James E. Clarkson         
United States, Missouri
Saint Francis Medical Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Saint Louis Cancer and Breast Institute-South City Recruiting
Saint Louis, Missouri, United States, 63109
Contact: Jay W. Carlson    314-353-1870      
Principal Investigator: Jay W. Carlson         
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Mercy Hospital Saint Louis Recruiting
Saint Louis, Missouri, United States, 63141
Contact: Jay W. Carlson    314-251-6770      
Principal Investigator: Jay W. Carlson         
United States, Nebraska
CHI Health Saint Francis Recruiting
Grand Island, Nebraska, United States, 68803
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
United States, Nevada
Renown Regional Medical Center Recruiting
Reno, Nevada, United States, 89502
Contact: John A. Ellerton    702-384-0013      
Principal Investigator: John A. Ellerton         
United States, New Hampshire
Dartmouth Hitchcock Medical Center Recruiting
Lebanon, New Hampshire, United States, 03756
Contact: Mary D. Chamberlin    603-354-5454 ext 2155    jmichelson@cheshire-med.com   
Principal Investigator: Mary D. Chamberlin         
Norris Cotton Cancer Center-Manchester Recruiting
Manchester, New Hampshire, United States, 03102
Contact: Mary D. Chamberlin    603-354-5454 ext 2155    jmichelson@cheshire-med.com   
Principal Investigator: Mary D. Chamberlin         
Saint Joseph Hospital Recruiting
Nashua, New Hampshire, United States, 03060
Contact: Umit Tapan    603-880-3408    carcieri@sjh-nh.org   
Principal Investigator: Umit Tapan         
Norris Cotton Cancer Center-Nashua Recruiting
Nashua, New Hampshire, United States, 03063
Contact: Mary D. Chamberlin    603-354-5454 ext 2155    jmichelson@cheshire-med.com   
Principal Investigator: Mary D. Chamberlin         
United States, New Jersey
Hackensack University Medical Center Recruiting
Hackensack, New Jersey, United States, 07601
Contact: Deena M. Graham    201-996-2879      
Principal Investigator: Deena M. Graham         
Saint Barnabas Medical Center Recruiting
Livingston, New Jersey, United States, 07039
Contact: Anna M. Litvak    973-322-2470      
Principal Investigator: Anna M. Litvak         
Monmouth Medical Center Recruiting
Long Branch, New Jersey, United States, 07740
Contact: Seth D. Cohen    732-923-7689      
Principal Investigator: Seth D. Cohen         
Virtua Memorial Recruiting
Mount Holly, New Jersey, United States, 08060
Contact: James W. Lee    609-914-6762      
Principal Investigator: James W. Lee         
Virtua Voorhees Recruiting
Voorhees, New Jersey, United States, 08043
Contact: James W. Lee    609-914-6762      
Principal Investigator: James W. Lee         
United States, New Mexico
Lovelace Medical Center-Saint Joseph Square Recruiting
Albuquerque, New Mexico, United States, 87102
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
University of New Mexico Cancer Center Recruiting
Albuquerque, New Mexico, United States, 87102
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
New Mexico Oncology Hematology Consultants Recruiting
Albuquerque, New Mexico, United States, 87109
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Presbyterian Kaseman Hospital Recruiting
Albuquerque, New Mexico, United States, 87110
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Memorial Medical Center - Las Cruces Recruiting
Las Cruces, New Mexico, United States, 88011
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
Christus Saint Vincent Regional Cancer Center Recruiting
Santa Fe, New Mexico, United States, 87505
Contact: Ursa A. Brown-Glaberman    505-925-0366    LByatt@nmcca.org   
Principal Investigator: Ursa A. Brown-Glaberman         
United States, New York
Roswell Park Cancer Institute Recruiting
Buffalo, New York, United States, 14263
Contact: Ellis G. Levine    877-275-7724      
Principal Investigator: Ellis G. Levine         
Arnot Ogden Medical Center/Falck Cancer Center Recruiting
Elmira, New York, United States, 14905
Contact: Serge Dauphin    607-271-7000      
Principal Investigator: Serge Dauphin         
Orange Regional Medical Center Recruiting
Middletown, New York, United States, 10940
Contact: Jeffrey M. Stewart    845-342-7609      
Principal Investigator: Jeffrey M. Stewart         
NYU Winthrop Hospital Recruiting
Mineola, New York, United States, 11501
Contact: Nina D'Abreo    516-663-3115      
Principal Investigator: Nina D'Abreo         
Beth Israel Medical Center Recruiting
New York, New York, United States, 10003
Contact: Paula Klein    212-844-6286      
Principal Investigator: Paula Klein         
Laura and Isaac Perlmutter Cancer Center at NYU Langone Recruiting
New York, New York, United States, 10016
Contact: Sylvia Adams    212-263-4434    prmc.coordinator@nyumc.org   
Principal Investigator: Sylvia Adams         
Columbia University/Herbert Irving Cancer Center Recruiting
New York, New York, United States, 10032
Contact: Meghna S. Trivedi    212-305-8615      
Principal Investigator: Meghna S. Trivedi         
Weill Medical College of Cornell University Recruiting
New York, New York, United States, 10065
Contact: Eleni Andreopoulou    212-746-1848      
Principal Investigator: Eleni Andreopoulou         
Dickstein Cancer Treatment Center Recruiting
White Plains, New York, United States, 10601
Contact: Dan Costin    914-849-7582    mcortese@wphospital.org   
Principal Investigator: Dan Costin         
United States, North Carolina
Randolph Hospital Recruiting
Asheboro, North Carolina, United States, 27203
Contact: Vinay K. Gudena    336-832-0821      
Principal Investigator: Vinay K. Gudena         
Cone Health Cancer Center at Alamance Regional Recruiting
Burlington, North Carolina, United States, 27215
Contact: Vinay K. Gudena    336-832-0821      
Principal Investigator: Vinay K. Gudena         
UNC Lineberger Comprehensive Cancer Center Recruiting
Chapel Hill, North Carolina, United States, 27599
Contact: Elizabeth C. Dees    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: Elizabeth C. Dees         
Novant Health Presbyterian Medical Center Recruiting
Charlotte, North Carolina, United States, 28204
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Oncology Specialists of Charlotte Recruiting
Charlotte, North Carolina, United States, 28207
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Southeastern Medical Oncology Center-Clinton Recruiting
Clinton, North Carolina, United States, 28328
Contact: James N. Atkins    252-399-7491      
Principal Investigator: James N. Atkins         
Southeastern Medical Oncology Center-Goldsboro Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Cone Health Cancer Center Recruiting
Greensboro, North Carolina, United States, 27403
Contact: Vinay K. Gudena    336-832-0821      
Principal Investigator: Vinay K. Gudena         
Margaret R Pardee Memorial Hospital Recruiting
Hendersonville, North Carolina, United States, 28791
Contact: James E. Radford    828-696-1341      
Principal Investigator: James E. Radford         
Lake Norman Hematology Oncology Specialists-Huntersville Recruiting
Huntersville, North Carolina, United States, 28078
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Southern Oncology Specialists-Huntersville Recruiting
Huntersville, North Carolina, United States, 28078
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Southeastern Medical Oncology Center-Jacksonville Recruiting
Jacksonville, North Carolina, United States, 28546
Contact: James N. Atkins    888-774-0309      
Principal Investigator: James N. Atkins         
Kinston Medical Specialists PA Recruiting
Kinston, North Carolina, United States, 28501
Contact: Peter R. Watson    252-559-2200      
Principal Investigator: Peter R. Watson         
Novant Health Cancer Specialists-Matthews Recruiting
Matthews, North Carolina, United States, 28105
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Cone Heath Cancer Center at Mebane Recruiting
Mebane, North Carolina, United States, 27302
Contact: Vinay K. Gudena    336-832-0821      
Principal Investigator: Vinay K. Gudena         
Lake Norman Hematology Oncology Specialists-Mooresville Recruiting
Mooresville, North Carolina, United States, 28117
Contact: Nasfat Shehadeh    704-384-5369      
Principal Investigator: Nasfat Shehadeh         
Annie Penn Memorial Hospital Recruiting
Reidsville, North Carolina, United States, 27320
Contact: Vinay K. Gudena    336-832-0821      
Principal Investigator: Vinay K. Gudena         
United States, North Dakota
Sanford Bismarck Medical Center Recruiting
Bismarck, North Dakota, United States, 58501
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Roger Maris Cancer Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Sanford Broadway Medical Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Sanford Clinic North-Fargo Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
United States, Ohio
UHHS-Chagrin Highlands Medical Center Recruiting
Beachwood, Ohio, United States, 44122
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Strecker Cancer Center-Belpre Recruiting
Belpre, Ohio, United States, 45714
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Adena Regional Medical Center Recruiting
Chillicothe, Ohio, United States, 45601
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Case Western Reserve University Recruiting
Cleveland, Ohio, United States, 44106
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Ohio State University Comprehensive Cancer Center Recruiting
Columbus, Ohio, United States, 43210
Contact: Sagar D. Sardesai    800-293-5066    Jamesline@osumc.edu   
Principal Investigator: Sagar D. Sardesai         
Mount Carmel East Hospital Recruiting
Columbus, Ohio, United States, 43213
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Columbus Oncology and Hematology Associates Inc Recruiting
Columbus, Ohio, United States, 43214
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Riverside Methodist Hospital Recruiting
Columbus, Ohio, United States, 43214
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
The Mark H Zangmeister Center Recruiting
Columbus, Ohio, United States, 43219
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Mount Carmel Health Center West Recruiting
Columbus, Ohio, United States, 43222
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Doctors Hospital Recruiting
Columbus, Ohio, United States, 43228
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Delaware Health Center-Grady Cancer Center Recruiting
Delaware, Ohio, United States, 43015
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Grady Memorial Hospital Recruiting
Delaware, Ohio, United States, 43015
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Mercy Cancer Center-Elyria Recruiting
Elyria, Ohio, United States, 44035
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
OhioHealth Mansfield Hospital Recruiting
Mansfield, Ohio, United States, 44903
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Marietta Memorial Hospital Recruiting
Marietta, Ohio, United States, 45750
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
OneHealth Marion General Hospital Recruiting
Marion, Ohio, United States, 43302
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Lake University Ireland Cancer Center Recruiting
Mentor, Ohio, United States, 44060
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Southwest General Health Center Ireland Cancer Center Recruiting
Middleburg Heights, Ohio, United States, 44130
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Knox Community Hospital Recruiting
Mount Vernon, Ohio, United States, 43050
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Licking Memorial Hospital Recruiting
Newark, Ohio, United States, 43055
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
University Hospitals Parma Medical Center Recruiting
Parma, Ohio, United States, 44129
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Southern Ohio Medical Center Recruiting
Portsmouth, Ohio, United States, 45662
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Ireland Cancer Center at Firelands Regional Medical Center Recruiting
Sandusky, Ohio, United States, 44870
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Flower Hospital Recruiting
Sylvania, Ohio, United States, 43560
Contact: Abhijit B. Saste    419-824-1842      
Principal Investigator: Abhijit B. Saste         
The Toledo Hospital/Toledo Children's Hospital Recruiting
Toledo, Ohio, United States, 43606
Contact: Abhijit B. Saste    419-824-1842      
Principal Investigator: Abhijit B. Saste         
University Hospitals Sharon Health Center Recruiting
Wadsworth, Ohio, United States, 44281
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Saint Ann's Hospital Recruiting
Westerville, Ohio, United States, 43081
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
UH-Seidman Cancer Center at Saint John Medical Center Recruiting
Westlake, Ohio, United States, 44145
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
UHHS-Westlake Medical Center Recruiting
Westlake, Ohio, United States, 44145
Contact: Shaveta Vinayak    800-641-2422      
Principal Investigator: Shaveta Vinayak         
Genesis Healthcare System Cancer Care Center Recruiting
Zanesville, Ohio, United States, 43701
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: Wajeeha Razaq    402-559-6941    unmcrsa@unmc.edu   
Principal Investigator: Wajeeha Razaq         
Mercy Hospital Oklahoma City Recruiting
Oklahoma City, Oklahoma, United States, 73120
Contact: Jay W. Carlson    405-751-4343      
Principal Investigator: Jay W. Carlson         
United States, Oregon
Saint Alphonsus Medical Center-Baker City Recruiting
Baker City, Oregon, United States, 97814
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Providence Oncology and Hematology Care Southeast Recruiting
Clackamas, Oregon, United States, 97015
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Good Samaritan Hospital Recruiting
Corvallis, Oregon, United States, 97330
Contact: David M. Hufnagel    541-768-4352    stmock@samhealth.org   
Principal Investigator: David M. Hufnagel         
Legacy Mount Hood Medical Center Recruiting
Gresham, Oregon, United States, 97030
Contact: Jacqueline Vuky    503-413-2150      
Principal Investigator: Jacqueline Vuky         
Providence Newberg Medical Center Recruiting
Newberg, Oregon, United States, 97132
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Saint Alphonsus Medical Center-Ontario Recruiting
Ontario, Oregon, United States, 97914
Contact: Christopher M. Reynolds    734-712-3671      
Principal Investigator: Christopher M. Reynolds         
Legacy Good Samaritan Hospital and Medical Center Recruiting
Portland, Oregon, United States, 97210
Contact: Jacqueline Vuky    800-220-4937    cancer@lhs.org   
Principal Investigator: Jacqueline Vuky         
Providence Portland Medical Center Recruiting
Portland, Oregon, United States, 97213
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Providence Saint Vincent Medical Center Recruiting
Portland, Oregon, United States, 97225
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Kaiser Permanente Northwest Recruiting
Portland, Oregon, United States, 97227
Contact: Sandeep H. Mashru    503-335-2400      
Principal Investigator: Sandeep H. Mashru         
Oregon Health and Science University Recruiting
Portland, Oregon, United States, 97239
Contact: Zahi Mitri    503-494-1080    trials@ohsu.edu   
Principal Investigator: Zahi Mitri         
SWOG Recruiting
Portland, Oregon, United States, 97239
Contact: Lajos Pusztai    203-785-5702      
Principal Investigator: Lajos Pusztai         
Legacy Meridian Park Hospital Recruiting
Tualatin, Oregon, United States, 97062
Contact: Jacqueline Vuky    503-413-1742      
Principal Investigator: Jacqueline Vuky         
United States, Pennsylvania
Abington Memorial Hospital Recruiting
Abington, Pennsylvania, United States, 19001
Contact: Willard G. Andrews    215-481-2402      
Principal Investigator: Willard G. Andrews         
Bryn Mawr Hospital Recruiting
Bryn Mawr, Pennsylvania, United States, 19010
Contact: Albert S. DeNittis    484-476-2649    ewend@mlhs.org   
Principal Investigator: Albert S. DeNittis         
Jefferson Hospital Recruiting
Jefferson Hills, Pennsylvania, United States, 15025
Contact: Christie J. Hilton    724-226-7380      
Principal Investigator: Christie J. Hilton         
Riddle Memorial Hospital Recruiting
Media, Pennsylvania, United States, 19063
Contact: Albert S. DeNittis    484-476-2649    ewend@mlhs.org   
Principal Investigator: Albert S. DeNittis         
Forbes Hospital Recruiting
Monroeville, Pennsylvania, United States, 15146
Contact: Christie J. Hilton    724-226-7380      
Principal Investigator: Christie J. Hilton         
Paoli Memorial Hospital Recruiting
Paoli, Pennsylvania, United States, 19301
Contact: Albert S. DeNittis    484-476-2649    ewend@mlhs.org   
Principal Investigator: Albert S. DeNittis         
Thomas Jefferson University Hospital Recruiting
Philadelphia, Pennsylvania, United States, 19107
Contact: Maysa M. Abu-Khalaf    215-955-6084      
Principal Investigator: Maysa M. Abu-Khalaf         
Allegheny General Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15212
Contact: Christie J. Hilton    724-226-7380      
Principal Investigator: Christie J. Hilton         
West Penn Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15224
Contact: Christie J. Hilton    724-226-7380      
Principal Investigator: Christie J. Hilton         
University of Pittsburgh Cancer Institute (UPCI) Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Rachel C. Jankowitz    412-647-2811      
Principal Investigator: Rachel C. Jankowitz         
Reading Hospital Recruiting
West Reading, Pennsylvania, United States, 19611
Contact: Terrence P. Cescon    610-988-9323      
Principal Investigator: Terrence P. Cescon         
Wexford Health and Wellness Pavilion Recruiting
Wexford, Pennsylvania, United States, 15090
Contact: Christie J. Hilton    724-226-7380      
Principal Investigator: Christie J. Hilton         
UPMC Susquehanna Recruiting
Williamsport, Pennsylvania, United States, 17701
Contact: Warren L. Robinson    412-647-8073      
Principal Investigator: Warren L. Robinson         
Lankenau Medical Center Recruiting
Wynnewood, Pennsylvania, United States, 19096
Contact: Albert S. DeNittis    484-476-2649    ewend@mlhs.org   
Principal Investigator: Albert S. DeNittis         
United States, South Carolina
AnMed Health Cancer Center Recruiting
Anderson, South Carolina, United States, 29621
Contact: John E. Doster    864-512-1000      
Principal Investigator: John E. Doster         
Medical University of South Carolina Recruiting
Charleston, South Carolina, United States, 29425
Contact: Antonio Giordano    843-792-9321      
Principal Investigator: Antonio Giordano         
Greenville Health System Cancer Institute-Laurens Recruiting
Clinton, South Carolina, United States, 29325
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Easley Recruiting
Easley, South Carolina, United States, 29640
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Gibbs Cancer Center-Gaffney Recruiting
Gaffney, South Carolina, United States, 29341
Contact: Steven W. Corso    800-486-5941      
Principal Investigator: Steven W. Corso         
Saint Francis Hospital Recruiting
Greenville, South Carolina, United States, 29601
Contact: Robert D. Siegel    864-255-1713      
Principal Investigator: Robert D. Siegel         
Greenville Health System Cancer Institute-Butternut Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Faris Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Saint Francis Cancer Center Recruiting
Greenville, South Carolina, United States, 29607
Contact: Robert D. Siegel    864-255-1713      
Principal Investigator: Robert D. Siegel         
Greenville Health System Cancer Institute-Eastside Recruiting
Greenville, South Carolina, United States, 29615
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Self Regional Healthcare Recruiting
Greenwood, South Carolina, United States, 29646
Contact: Antonio Giordano    864-725-4771      
Principal Investigator: Antonio Giordano         
Greenville Health System Cancer Institute-Greer Recruiting
Greer, South Carolina, United States, 29650
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Gibbs Cancer Center-Pelham Recruiting
Greer, South Carolina, United States, 29651
Contact: Steven W. Corso    800-486-5941      
Principal Investigator: Steven W. Corso         
South Carolina Cancer Specialists PC Recruiting
Hilton Head Island, South Carolina, United States, 29926-3827
Contact: Howard A. Zaren    912-819-5704      
Principal Investigator: Howard A. Zaren         
Greenville Health System Cancer Institute-Seneca Recruiting
Seneca, South Carolina, United States, 29672
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Spartanburg Medical Center Recruiting
Spartanburg, South Carolina, United States, 29303
Contact: Steven W. Corso    800-486-5941      
Principal Investigator: Steven W. Corso         
Greenville Health System Cancer Institute-Spartanburg Recruiting
Spartanburg, South Carolina, United States, 29307
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
MGC Hematology Oncology-Union Recruiting
Union, South Carolina, United States, 29379
Contact: Steven W. Corso    800-486-5941      
Principal Investigator: Steven W. Corso         
United States, South Dakota
Sanford Cancer Center Oncology Clinic Recruiting
Sioux Falls, South Dakota, United States, 57104
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Sanford USD Medical Center - Sioux Falls Recruiting
Sioux Falls, South Dakota, United States, 57117-5134
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
United States, Tennessee
Vanderbilt-Ingram Cancer Center Cool Springs Recruiting
Franklin, Tennessee, United States, 37067
Contact: Brent N. Rexer    800-811-8480      
Principal Investigator: Brent N. Rexer         
Thompson Cancer Survival Center Recruiting
Knoxville, Tennessee, United States, 37916
Contact: Jashmin K. Patel    865-331-1812      
Principal Investigator: Jashmin K. Patel         
Thompson Cancer Survival Center - West Recruiting
Knoxville, Tennessee, United States, 37932
Contact: Jashmin K. Patel    865-331-1812      
Principal Investigator: Jashmin K. Patel         
Thompson Oncology Group-Lenoir City Recruiting
Lenoir City, Tennessee, United States, 37772
Contact: Jashmin K. Patel    865-331-1812      
Principal Investigator: Jashmin K. Patel         
Vanderbilt Breast Center at One Hundred Oaks Recruiting
Nashville, Tennessee, United States, 37204
Contact: Brent N. Rexer    800-811-8480      
Principal Investigator: Brent N. Rexer         
Vanderbilt University/Ingram Cancer Center Recruiting
Nashville, Tennessee, United States, 37232
Contact: Brent N. Rexer    800-811-8480      
Principal Investigator: Brent N. Rexer         
Thompson Oncology Group-Oak Ridge Recruiting
Oak Ridge, Tennessee, United States, 37830
Contact: Jashmin K. Patel    865-331-1812      
Principal Investigator: Jashmin K. Patel         
United States, Texas
The Don and Sybil Harrington Cancer Center Recruiting
Amarillo, Texas, United States, 79106
Contact: Brian T. Pruitt    806-212-1985    gcravey@harringtoncc.org   
Principal Investigator: Brian T. Pruitt         
Lyndon Baines Johnson General Hospital Recruiting
Houston, Texas, United States, 77026-1967
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Julie R. Nangia    713-798-1354    burton@bcm.edu   
Principal Investigator: Julie R. Nangia         
Ben Taub General Hospital Recruiting
Houston, Texas, United States, 77030
Contact: Julie R. Nangia    713-873-2000      
Principal Investigator: Julie R. Nangia         
M D Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
MD Anderson Regional Care Center-Katy Recruiting
Houston, Texas, United States, 77094
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
MD Anderson Regional Care Center-Bay Area Recruiting
Nassau Bay, Texas, United States, 77058
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
MD Anderson Regional Care Center-Sugar Land Recruiting
Sugar Land, Texas, United States, 77478
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
MD Anderson Regional Care Center-The Woodlands Recruiting
The Woodlands, Texas, United States, 77384
Contact: Jennifer K. Litton    713-792-3245      
Principal Investigator: Jennifer K. Litton         
United States, Vermont
Norris Cotton Cancer Center-North Recruiting
Saint Johnsbury, Vermont, United States, 05819
Contact: Mary D. Chamberlin    603-354-5454 ext 2155    jmichelson@cheshire-med.com   
Principal Investigator: Mary D. Chamberlin         
United States, Virginia
IMG Hematology Oncology 8501 Recruiting
Fairfax, Virginia, United States, 22031
Contact: Mary J. Wilkinson    703-208-6650    Stephanie.VanBebber@inova.org   
Principal Investigator: Mary J. Wilkinson         
Bon Secours Memorial Regional Medical Center Recruiting
Mechanicsville, Virginia, United States, 23116
Contact: William J. Irvin    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: William J. Irvin         
Bon Secours Saint Francis Medical Center Recruiting
Midlothian, Virginia, United States, 23114
Contact: William J. Irvin    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: William J. Irvin         
Bon Secours Saint Mary's Hospital Recruiting
Richmond, Virginia, United States, 23226
Contact: William J. Irvin    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: William J. Irvin         
United States, Washington
Harrison HealthPartners Hematology and Oncology-Bremerton Recruiting
Bremerton, Washington, United States, 98310
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Kadlec Clinic Hematology and Oncology Recruiting
Kennewick, Washington, United States, 99336
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Seattle Cancer Care Alliance at EvergreenHealth Recruiting
Kirkland, Washington, United States, 98034
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
PeaceHealth Saint John Medical Center Recruiting
Longview, Washington, United States, 98632
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Skagit Valley Hospital Regional Cancer Care Center Recruiting
Mount Vernon, Washington, United States, 98273
Contact: Julie R. Gralow    360-814-2146    rcccclinicalresearch@skagitvalleyhospital.org   
Principal Investigator: Julie R. Gralow         
Skagit Valley Hospital Recruiting
Mount Vernon, Washington, United States, 98274
Contact: Julie R. Gralow    360-814-2687    rcccclinicalresearch@skagitvalleyhospital.org   
Principal Investigator: Julie R. Gralow         
Harrison HealthPartners Hematology and Oncology-Poulsbo Recruiting
Poulsbo, Washington, United States, 98370
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Fred Hutchinson Cancer Research Center Recruiting
Seattle, Washington, United States, 98109
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
Seattle Cancer Care Alliance Recruiting
Seattle, Washington, United States, 98109
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
Swedish Medical Center-First Hill Recruiting
Seattle, Washington, United States, 98122-4307
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Seattle Cancer Care Alliance at Northwest Hospital Recruiting
Seattle, Washington, United States, 98133
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
University of Washington Medical Center Recruiting
Seattle, Washington, United States, 98195
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
Spokane Valley Cancer Center-Mayfair Recruiting
Spokane, Washington, United States, 99208
Contact: Julie R. Gralow    800-422-6237      
Principal Investigator: Julie R. Gralow         
PeaceHealth Southwest Medical Center Recruiting
Vancouver, Washington, United States, 98664
Contact: Gary E. Goodman    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Gary E. Goodman         
Legacy Salmon Creek Hospital Recruiting
Vancouver, Washington, United States, 98686
Contact: Jacqueline Vuky    503-413-2150      
Principal Investigator: Jacqueline Vuky         
United States, West Virginia
Edwards Comprehensive Cancer Center Recruiting
Huntington, West Virginia, United States, 25701
Contact: Maria R. Tria Tirona    304-399-6617      
Principal Investigator: Maria R. Tria Tirona         
United States, Wisconsin
Gundersen Lutheran Medical Center Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: David E. Marinier    608-775-2385    cancerctr@gundersenhealth.org   
Principal Investigator: David E. Marinier         
ProHealth D N Greenwald Center Recruiting
Mukwonago, Wisconsin, United States, 53149
Contact: Timothy R. Wassenaar    262-928-7632      
Principal Investigator: Timothy R. Wassenaar         
Cancer Center of Western Wisconsin Recruiting
New Richmond, Wisconsin, United States, 54017
Contact: David M. King    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: David M. King         
ProHealth Oconomowoc Memorial Hospital Recruiting
Oconomowoc, Wisconsin, United States, 53066
Contact: Timothy R. Wassenaar    262-928-7632      
Principal Investigator: Timothy R. Wassenaar         
ProHealth Waukesha Memorial Hospital Recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Timothy R. Wassenaar    262-928-7632      
Principal Investigator: Timothy R. Wassenaar         
UW Cancer Center at ProHealth Care Recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Timothy R. Wassenaar    262-928-7632      
Principal Investigator: Timothy R. Wassenaar         
Puerto Rico
Cancer Center-Metro Medical Center Bayamon Recruiting
Bayamon, Puerto Rico, 00959-5060
Contact: Luis Baez-Diaz    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Luis Baez-Diaz         
Doctors Cancer Center Recruiting
Manati, Puerto Rico, 00674
Contact: Luis Baez-Diaz    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Luis Baez-Diaz         
Hato Rey Hematology Oncology Group Recruiting
San Juan, Puerto Rico, 00917
Contact: Luis Baez-Diaz    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Luis Baez-Diaz         
San Juan City Hospital Recruiting
San Juan, Puerto Rico, 00936
Contact: Luis Baez-Diaz    787-767-3733      
Principal Investigator: Luis Baez-Diaz         
Sponsors and Collaborators
National Cancer Institute (NCI)
Investigators
Principal Investigator: Lajos Pusztai Southwest Oncology Group
More Information

Responsible Party: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT02954874     History of Changes
Other Study ID Numbers: NCI-2016-01595
NCI-2016-01595 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
S1418/BR006
s16-02231
S1418 ( Other Identifier: SWOG )
S1418 ( Other Identifier: CTEP )
U10CA180888 ( U.S. NIH Grant/Contract )
First Posted: November 4, 2016    Key Record Dates
Last Update Posted: January 11, 2018
Last Verified: November 2017

Additional relevant MeSH terms:
Carcinoma
Breast Neoplasms
Triple Negative Breast Neoplasms
Breast Carcinoma In Situ
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Carcinoma in Situ
Pembrolizumab
Antineoplastic Agents