Comparison of Aqueous and Plasma Glucose Level in Diabetic Patients
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|ClinicalTrials.gov Identifier: NCT02750098|
Recruitment Status : Unknown
Verified April 2016 by Prof. Irina Barequet, Sheba Medical Center.
Recruitment status was: Not yet recruiting
First Posted : April 25, 2016
Last Update Posted : April 25, 2016
Comparison of aqueous and plasma glucose level in diabetic patients
High glucose concentrations in aqueous humor are thought to be related of diabetic ocular injury, including cataract and diabetic keratopathy. The primary mechanisms are nonenzymatic glycation, oxidative stress and activation of polyol pathway. However, glucose concentrations in aqueous humor of diabetic patients was only examined in a few patients in the past.
This study will compare glucose concentration in blood plasma and aqueous humor in diabetic patients undergoing cataract surgery. Perioperative Hemoglobin A1c concentrations will also be examined. Correlation between these parameters will be analyzed.
|Condition or disease||Intervention/treatment||Phase|
|Diabetes Mellitus||Other: Glucose measurement||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||25 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Comparison of Aqueous and Plasma Glucose Level in Diabetic Patients|
|Study Start Date :||May 2016|
|Estimated Primary Completion Date :||December 2017|
|Estimated Study Completion Date :||March 2018|
Experimental: Diabetic patients
Diabetic patients planned to undergo elective cataract surgery
Other: Glucose measurement
- Aqueous humor glucose concentration [ Time Frame: Day of cataract surgery ]
- Plasma glucose concentrations [ Time Frame: Day of cataract surgery ]
- Hemoglobin A1c [ Time Frame: Perioperative month ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02750098
|Contact: Lior Lipsky, MDfirstname.lastname@example.org|
|Contact: Irit Barequet, MDemail@example.com|