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Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease (FIGARO-DKD)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02545049
Recruitment Status : Completed
First Posted : September 9, 2015
Results First Posted : April 15, 2022
Last Update Posted : April 15, 2022
Information provided by (Responsible Party):

Brief Summary:
The purpose of this study was to evaluate whether oral finerenone (study drug), in addition to standard daily therapy, is effective and safe in treating patients with type 2 diabetes mellitus and diabetic kidney disease, when compared to a placebo.

Condition or disease Intervention/treatment Phase
Diabetic Kidney Disease Drug: Finerenone (BAY94-8862) Drug: Placebo Phase 3

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 7352 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Event-driven Phase 3 Study to Investigate Efficacy and Safety of Finerenone on the Reduction of Cardiovascular Morbidity and Mortality in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease in Addition to Standard of Care.
Actual Study Start Date : September 17, 2015
Actual Primary Completion Date : February 2, 2021
Actual Study Completion Date : February 2, 2021

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: BAY94-8862
Finerenone tablet
Drug: Finerenone (BAY94-8862)
10 mg or 20 mg Finerenone tablet to be given orally, once daily.

Placebo Comparator: Placebo
Matching placebo
Drug: Placebo
Matching placebo to be taken orally, once daily.

Primary Outcome Measures :
  1. The First Occurrence of the Composite Endpoint of Cardiovascular Death, Non-fatal Myocardial Infarction, Non Fatal Stroke, or Hospitalization for Heart Failure. [ Time Frame: From randomization up until the first occurrence of the CV composite endpoint, or censoring at the end of the study, with an average study duration of 41 months. ]
    Number of participants with the first occurrence of the primary cardiovascular (CV) composite outcome, CV death, non-fatal myocardial infarction (MI), non-fatal stroke, or hospitalization for heart failure were reported as descriptive result.

Secondary Outcome Measures :
  1. The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease of eGFR ≥40% From Baseline Over at Least 4 Weeks, or Renal Death. [ Time Frame: From randomization up until the first occurrence of the renal composite endpoint, or censoring at the end of the study, with an average study duration of 41 months. ]
    Number of participants with first occurrence of the composite endpoint of onset of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death were reported as descriptive result.

  2. All-cause Hospitalization [ Time Frame: From randomization up until the first occurrence of the hospitalization due to any cause, or censoring at the end of study, with an average study duration of 41 months ]
    Number of participants with first occurrence of a hospitalization event were reported as descriptive result.

  3. All-cause Mortality [ Time Frame: From randomization up until death due to any cause, or censoring at the end of the study, with an average study duration of 41 months ]
    Number of participants with death due to any cause were reported as descriptive result. Number of participants with outcome death reported here includes deaths occurred after randomization until the end of the study visit. Deaths after end of study visit are not included in this table.

  4. Change in Urinary Albumin-to-creatine Ratio (UCAR) From Baseline to Month 4 [ Time Frame: From baseline up until Month 4 ]
    First morning void urine samples were collected to evaluate the urinary albumin-to-creatinine ratio (UACR). Month 4 was the visit closest to day 120 within a time window of 120 ± 30 days after randomization. If no measurements were available in this time window, the participant was excluded from this analysis. Ratio of UACR at Month 4 to UACR at baseline is reported as the change.

  5. The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease in eGFR of ≥57% From Baseline Over at Least 4 Weeks, or Renal Death [ Time Frame: From randomization up until the first occurrence of the renal composite endpoint, or censoring at the end of the study, with an average study duration of 41 months ]
    Number of participants with first occurrence of the renal composite outcome, onset of kidney failure, a sustained decrease in eGFR of ≥57% from baseline over at least 4 weeks, or renal death were reported as descriptive result.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Men or women ≥18 years of age
  • Subjects with Type Type 2 Diabetes Mellitus as defined by the American Diabetes Association
  • Diagnosis of Diabetic Kidney Disease with persistent high albuminuria or persistent very high albuminuria at the Run-In and Screening Visit
  • Pretreated with either angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) at maximal tolerated labeled dose without adjustments
  • Serum potassium <=4.8 mmol/L

Exclusion Criteria:

  • Confirmed significant non-diabetic renal disease, including clinically relevant renal artery stenosis
  • Uncontrolled arterial hypertension (ie, mean sitting systolic blood pressure (SBP) ≥170 mmHg or mean sitting diastolic blood pressure(DBP) ≥110 mmHg at run in visit, or mean sitting SBP ≥160 mmHg or mean sitting DBP ≥100 mmHg at screening)
  • Clinical diagnosis of chronic heart failure with reduced ejection fraction (HFrEF) and persistent symptoms {New York Heart Association (NYHA) class II - IV} at Run in visit [class 1A recommendation for mineralcorticoid receptor antagonist (MRAs)]
  • Dialysis for acute renal failure within 12 weeks of Run-in visit
  • Renal allograft in place or scheduled kidney transplant within next 12 months
  • Glycated hemoglobin (HbA1c) >12%

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02545049

Hide Hide 975 study locations
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United States, Alabama
Birmingham, Alabama, United States, 35294-2041
Fort Payne, Alabama, United States, 35967
Huntsville, Alabama, United States, 35801-4317
United States, Arizona
Mesa, Arizona, United States, 85210
Phoenix, Arizona, United States, 85016
Phoenix, Arizona, United States, 85032
Prescott, Arizona, United States, 86301
Tucson, Arizona, United States, 85723
Tucson, Arizona, United States, 85724
United States, California
Bakersfield, California, United States, 93309
Chula Vista, California, United States, 91910
Dublin, California, United States, 94568
El Centro, California, United States, 92243
Fresno, California, United States, 93720
Fresno, California, United States, 93721
La Mesa, California, United States, 91942
Loma Linda, California, United States, 92357
Los Angeles, California, United States, 90017
Los Angeles, California, United States, 90022
Los Angeles, California, United States, 90025
Los Angeles, California, United States, 90073
Northridge, California, United States, 91325
Port Hueneme, California, United States, 93041
Poway, California, United States, 92064
Rancho Cucamonga, California, United States, 91730
Rialto, California, United States, 92377
Roseville, California, United States, 95661
San Diego, California, United States, 92117
Santa Rosa, California, United States, 95405
Torrance, California, United States, 90502
Vista, California, United States, 92083
United States, Connecticut
New Haven, Connecticut, United States, 06520
Waterbury, Connecticut, United States, 06708
United States, Florida
Fort Lauderdale, Florida, United States, 33308
Fort Lauderdale, Florida, United States, 33312
Fort Lauderdale, Florida, United States, 33316-1958
Hialeah, Florida, United States, 33012
Hialeah, Florida, United States, 33016
Hollywood, Florida, United States, 33024
Jacksonville, Florida, United States, 32204
Miami Beach, Florida, United States, 33140
Miami Gardens, Florida, United States, 33014
Miami Lakes, Florida, United States, 33014
Miami Lakes, Florida, United States, 33016
Miami, Florida, United States, 33032
Miami, Florida, United States, 33126
Miami, Florida, United States, 33130
Miami, Florida, United States, 33144
Miami, Florida, United States, 33145
Miami, Florida, United States, 33155
Miami, Florida, United States, 33156
Miami, Florida, United States, 33165
Miami, Florida, United States, 33173
Miami, Florida, United States, 33175
Miami, Florida, United States, 33186
New Port Richey, Florida, United States, 34652
Ocala, Florida, United States, 34471
Orlando, Florida, United States, 32825
Palm Harbor, Florida, United States, 34684
Sarasota, Florida, United States, 34239
Tampa, Florida, United States, 33614
West Palm Beach, Florida, United States, 33401-3430
Winter Haven, Florida, United States, 33880
United States, Georgia
Atlanta, Georgia, United States, 30303
Atlanta, Georgia, United States, 30342
Augusta, Georgia, United States, 30904
Lawrenceville, Georgia, United States, 30046
Macon, Georgia, United States, 31210
United States, Hawaii
Honolulu, Hawaii, United States, 96814
United States, Illinois
Chicago, Illinois, United States, 60612
Elgin, Illinois, United States, 60123
Morton, Illinois, United States, 61550
Springfield, Illinois, United States, 62702-1311
United States, Indiana
Indianapolis, Indiana, United States, 46202
United States, Iowa
Iowa City, Iowa, United States, 52242
West Des Moines, Iowa, United States, 50265
United States, Kansas
Hutchinson, Kansas, United States, 67502-1131
Topeka, Kansas, United States, 66606
Wichita, Kansas, United States, 67214
United States, Louisiana
Metairie, Louisiana, United States, 70006
Monroe, Louisiana, United States, 71201
New Orleans, Louisiana, United States, 70112
Shreveport, Louisiana, United States, 71101
United States, Massachusetts
Boston, Massachusetts, United States, 02215
United States, Michigan
Ann Arbor, Michigan, United States, 48109
Flint, Michigan, United States, 48504
Flint, Michigan, United States, 48532
Kalamazoo, Michigan, United States, 49009
United States, Minnesota
Minneapolis, Minnesota, United States, 55455
United States, Missouri
Columbia, Missouri, United States, 65201
Columbia, Missouri, United States, 65212
Jefferson City, Missouri, United States, 65109
Kansas City, Missouri, United States, 64111
Kansas City, Missouri, United States, 64128
Saint Louis, Missouri, United States, 63106
Saint Louis, Missouri, United States, 63136
United States, Nebraska
Omaha, Nebraska, United States, 68124
Omaha, Nebraska, United States, 68131
United States, Nevada
Las Vegas, Nevada, United States, 89086
Las Vegas, Nevada, United States, 89102
Las Vegas, Nevada, United States, 89113-2215
Las Vegas, Nevada, United States, 89119
Las Vegas, Nevada, United States, 89128
Reno, Nevada, United States, 89511
United States, New Jersey
Newark, New Jersey, United States, 07103
United States, New Mexico
Albuquerque, New Mexico, United States, 87106
United States, New York
Albany, New York, United States, 12203
Brooklyn, New York, United States, 11203
Brooklyn, New York, United States, 11229
New York, New York, United States, 10029
Rosedale, New York, United States, 11422
Smithtown, New York, United States, 11787
Staten Island, New York, United States, 10301
United States, North Carolina
Asheboro, North Carolina, United States, 27203
Chapel Hill, North Carolina, United States, 27312
Charlotte, North Carolina, United States, 28207
Greenville, North Carolina, United States, 27834
New Bern, North Carolina, United States, 28562
Winston-Salem, North Carolina, United States, 27157
United States, Ohio
Canton, Ohio, United States, 44718
Willoughby Hills, Ohio, United States, 44094
United States, Pennsylvania
Beaver, Pennsylvania, United States, 15009
Bethlehem, Pennsylvania, United States, 18017
Hershey, Pennsylvania, United States, 17033
Jersey Shore, Pennsylvania, United States, 17740
United States, South Carolina
Anderson, South Carolina, United States, 29625
Charleston, South Carolina, United States, 29425
Greenville, South Carolina, United States, 29607
Murrells Inlet, South Carolina, United States, 29576
Myrtle Beach, South Carolina, United States, 29588
Orangeburg, South Carolina, United States, 29118
United States, Tennessee
Chattanooga, Tennessee, United States, 37404
Memphis, Tennessee, United States, 38104
Memphis, Tennessee, United States, 38120
Memphis, Tennessee, United States, 38163
Nashville, Tennessee, United States, 37205
Nashville, Tennessee, United States, 37208
Nashville, Tennessee, United States, 37232-1371
United States, Texas
Arlington, Texas, United States, 76014
Corpus Christi, Texas, United States, 78414
Dallas, Texas, United States, 75216
Dallas, Texas, United States, 75246
Dallas, Texas, United States, 75251
El Paso, Texas, United States, 79902-4672
Houston, Texas, United States, 77008
Houston, Texas, United States, 77018
Houston, Texas, United States, 77024
Houston, Texas, United States, 77040
Houston, Texas, United States, 77061
Houston, Texas, United States, 77079
Houston, Texas, United States, 77095
Kingwood, Texas, United States, 77339
McAllen, Texas, United States, 78503
McKinney, Texas, United States, 75069
Missouri City, Texas, United States, 77459
Pearland, Texas, United States, 77584
Pflugerville, Texas, United States, 78660
San Antonio, Texas, United States, 78212
San Antonio, Texas, United States, 78215
San Antonio, Texas, United States, 78229-3900
Sugar Land, Texas, United States, 77478
Sugar Land, Texas, United States, 77479
Tomball, Texas, United States, 77375
Waco, Texas, United States, 76708
United States, Utah
Salt Lake City, Utah, United States, 84108
United States, Vermont
Burlington, Vermont, United States, 05401
United States, Virginia
Alexandria, Virginia, United States, 22304
Charlottesville, Virginia, United States, 22908
Manassas, Virginia, United States, 20110
Salem, Virginia, United States, 24153
Virginia Beach, Virginia, United States, 23462
United States, Washington
Spokane, Washington, United States, 99204
Tacoma, Washington, United States, 98405
Caba, Buenos Aires, Argentina, C1120AAC
Junín, Buenos Aires, Argentina, B6000GMA
Lanús, Buenos Aires, Argentina, B1824KAJ
Mar del Plata, Buenos Aires, Argentina, B7602CBM
Sarandí, Buenos Aires, Argentina, 1872
Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina, C1056ABJ
Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina, C1426ABP
Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina, C1428ART
Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina, C1429BWN
Caba, Ciudad Auton. De Buenos Aires, Argentina, C1018DES
Ciudad Autón. de Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina, C1425AGC
Córdoba, Argentina, X5000AAW Córdoba
Córdoba, Argentina, X5000JHQ
San Luis, Argentina, D5702AAx
Australia, Australian Capital Territory
Garran, Australian Capital Territory, Australia, 2605
Australia, New South Wales
Gosford, New South Wales, Australia, 2250
Kanwal, New South Wales, Australia, 2259
Liverpool, New South Wales, Australia, 2170
New Lambton Heights, New South Wales, Australia, 2305
Wollongong, New South Wales, Australia, 2500
Australia, Queensland
Brisbane, Queensland, Australia, 4064
Australia, South Australia
Adelaide, South Australia, Australia, 5000
Australia, Victoria
Fitzroy, Victoria, Australia, 3065
Heidelberg, Victoria, Australia, 3081
Melbourne, Victoria, Australia, 3052
Prahran, Victoria, Australia, 3181
Reservoir, Victoria, Australia, 3073
Richmond, Victoria, Australia, 3121
St. Albans, Victoria, Australia, 3021
Elizabeth Vale, Australia, 5112
Linz, Oberösterreich, Austria, 4020
Linz, Oberösterreich, Austria, 4021
Graz, Steiermark, Austria, 8036
Saint Stefan, Steiermark, Austria, 8511
Zams, Tirol, Austria, 6511
Feldkirch, Vorarlberg, Austria, 6807
Innsbruck, Austria, 6020
Salzburg, Austria, 5020
Wels, Austria, 4600
Wien, Austria, 1030
Wien, Austria, 1060
Wien, Austria, 1090
Wien, Austria, 1130
Bruxelles - Brussel, Belgium, 1070
Edegem, Belgium, 2650
Gent, Belgium, 9000
Ieper, Belgium, 8900
Kortrijk, Belgium, 8500
Leuven, Belgium, 3000
Liege, Belgium, 4000
Roeselare, Belgium, 8800
Fortaleza, Ceará, Brazil, 60115-282
Fortaleza, Ceará, Brazil, 60430-140
Fortaleza, Ceará, Brazil
Brasilia, Distrito Federal, Brazil, 70.200-730
Aparecida de Goiania, Goiás, Brazil, 74935-530
Goiania, Goiás, Brazil, 74605-020
Juiz de Fora, Minas Gerais, Brazil, 36036-330
Uberlândia, Minas Gerais, Brazil, 38411-186
Campina Grande do Sul, Parana, Brazil, 83430 000
Curitiba, Parana, Brazil, 80030-110
Curitiba, Parana, Brazil, 80230-130
Curitiba, Parana, Brazil, 80440-020
Porto Alegre, Rio Grande Do Sul, Brazil, 90430-001
Porto Alegre, Rio Grande Do Sul, Brazil, 90610-000
São Bernardo do Campo, Sao Paulo, Brazil, 09715-090
São José do Rio Preto, Sao Paulo, Brazil, 15090-000
São José dos Campos, Sao Paulo, Brazil, 12243-280
São Paulo, Sao Paulo, Brazil, 04029-000
São Paulo, Sao Paulo, Brazil
Rio de Janeiro, Brazil, 20241-180
Rio de Janeiro, Brazil, 21941-913
Sao Paulo, Brazil, 01223-001
Sao Paulo, Brazil, 01228-200
Sao Paulo, Brazil, 04039-000
Blagoevgrad, Bulgaria, 2700
Botevgrad, Bulgaria, 2140
Dimitrovgrad, Bulgaria, 6400
Gorna Oryahovitsa, Bulgaria, 5100
Kazanlak, Bulgaria, 6102
Kozloduy, Bulgaria, 3320
Lukovit, Bulgaria, 5770
Plovdiv, Bulgaria, 4002
Plovdiv, Bulgaria, 4004
Razgrad, Bulgaria, 7200
Sliven, Bulgaria, 8800
Sofia, Bulgaria, 1233
Sofia, Bulgaria, 1407
Sofia, Bulgaria, 1606
Sofia, Bulgaria, 1680
Stara Zagora, Bulgaria, 6000
Varna, Bulgaria, 9000
Yambol, Bulgaria, 8600
Canada, Alberta
Edmonton, Alberta, Canada, T5A 4L8
Canada, British Columbia
Burnaby, British Columbia, Canada, V3J 1N4
Coquitlam, British Columbia, Canada, V3K 3P4
New Westminster, British Columbia, Canada, V3L 0A6
Canada, Newfoundland and Labrador
Mount Pearl, Newfoundland and Labrador, Canada, A1N 1W7
St. John's, Newfoundland and Labrador, Canada, A1A 3R5
Canada, Nova Scotia
Halifax, Nova Scotia, Canada, B3H 1V8
Canada, Ontario
Cambridge, Ontario, Canada, N1R 7L6
Hamilton, Ontario, Canada, L8M 1K7
Hamilton, Ontario, Canada, L8N 4A6
Kitchener, Ontario, Canada, N2G 4V5
Newmarket, Ontario, Canada, L3Y 5G8
Oshawa, Ontario, Canada, L1G 2B9
Ottawa, Ontario, Canada, K1K 4L2
Sarnia, Ontario, Canada, N7T 4X3
Smith Falls, Ontario, Canada, K7A 4W8
Sudbury, Ontario, Canada, P3A 1W8
Thornhill, Ontario, Canada, L4J 1W3
Toronto, Ontario, Canada, M3J 1N2
Toronto, Ontario, Canada, M4G 3E8
Toronto, Ontario, Canada, M5C 2T2
Waterloo, Ontario, Canada, N2J 1C4
Canada, Quebec
Greenfield Park, Quebec, Canada, J4V 2H1
Laval, Quebec, Canada, H7T 2P5
Mirabel, Quebec, Canada, J7J 2K8
Montreal, Quebec, Canada, H1M 1B1
Montreal, Quebec, Canada, H2K 1H2
Montreal, Quebec, Canada, H4A 3J1
Montreal, Quebec, Canada, H4A 3T2
Montreal, Quebec, Canada, H4J 1C5
Quebec, Canada, G1V 4W2
Osorno, Los Lagos, Chile, 5311092
Las Condes, Santiago, Chile, 7591047
Providencia, Santiago, Chile, 7500520
Providencia, Santiago, Chile, 7500922
San Bernardo, Santiago, Chile, 8053095
San Miguel, Santiago, Chile, 8910108
Santiago, Chile, 7500710
Santiago, Chile, 8331143
Santiago, Chile, 8380456
China, Fujian
Xiamen, Fujian, China, 361003
Xiamen, Fujian, China, 361004
China, Gansu
Lanzhou, Gansu, China, 730030
China, Guangdong
Guangzhou, Guangdong, China, 510080
Guangzhou, Guangdong, China, 510120
Guangzhou, Guangdong, China, 510150
Guangzhou, Guangdong, China, 510405
Guangzhou, Guangdong, China, 510630
Zhuhai, Guangdong, China, 519000
China, Guangxi
Nanning, Guangxi, China, 530021
Nanning, Guangxi, China, 530031
China, Hainan
Haikou, Hainan, China, 570102
Haikou, Hainan, China, 570311
China, Hubei
Wuhan, Hubei, China, 430022
Wuhan, Hubei, China, 430034
China, Hunan
Changsha, Hunan, China, 410008
Changsha, Hunan, China, 410011
Changsha, Hunan, China, 410013
China, Inner Mongolia
Hohhot, Inner Mongolia, China, 010017
China, Jiangsu
Changzhou, Jiangsu, China, 213004
Huai'An, Jiangsu, China, 223300
Lianyungang, Jiangsu, China, 222002
Nanjing, Jiangsu, China, 210002
Nanjing, Jiangsu, China, 210006
Nanjing, Jiangsu, China, 210008
Nanjing, Jiangsu, China, 210011
Nanjing, Jiangsu, China, 210029
Suzhou, Jiangsu, China, 215006
Wuxi, Jiangsu, China, 214023
Yancheng, Jiangsu, China, 224000
China, Jiangxi
Nanchang, Jiangxi, China, 330006
Nanchang, Jiangxi, China, 330008
China, Jilin
Changchun, Jilin, China, 130000
Changchun, Jilin, China, 130021
China, Liaoning
Shenyang, Liaoning, China, 110016
Shenyang, Liaoning, China, 110022
China, Ningxia
Yinchuan, Ningxia, China, 750004
China, Shaanxi
Xi'an, Shaanxi, China, 710061
China, Shandong
Qingdao, Shandong, China, 266071
China, Shanxi
Taiyuan, Shanxi, China, 030001
China, Sichuan
Chengdu, Sichuan, China, 610041
Chengdu, Sichuan, China, 610072
China, Xinjiang
Urumqi, Xinjiang, China, 830054
China, Zhejiang
Hangzhou, Zhejiang, China, 310013
Taizhou, Zhejiang, China, 317000
Wenzhou, Zhejiang, China, 325000
Beijing, China, 100028
Beijing, China, 100050
Beijing, China, 100071
Beijing, China, 100730
Chongqing, China, 400010
Shanghai, China, 200025
Shanghai, China, 200040
Shanghai, China, 200062
Shanghai, China, 200072
Shanghai, China, 200092
Shanghai, China, 200240
Shanghai, China, 201199
Tianjin, China, 300121
Tianjin, China, 300142
Medellin, Antioquia, Colombia, 050034
Medellín, Antioquia, Colombia, 0
Medellín, Antioquia, Colombia
Barranquilla, Atlántico, Colombia, 0
Barranquilla, Atlántico, Colombia
Manizales, Caldas, Colombia
Zipaquirá, Cundinamarca, Colombia, 0
Bogotá, Distrito Capital De Bogotá, Colombia, 0
Bogotá, Distrito Capital De Bogotá, Colombia
Cundinamarca, Distrito Capital De Bogotá, Colombia
Pasto, Nariño, Colombia
Armenia, Quindío, Colombia, 0
Pereira, Risaralda, Colombia
Cali, Valle Del Cauca, Colombia, 760032
Cali, Valle Del Cauca, Colombia
Barranquilla, Colombia
Bogota, Colombia
Floridablanca, Colombia
Medellín, Colombia
Beroun, Czechia, 266 01
Brandys nad Labem, Czechia, 250 01
Breclav, Czechia, 690 02
Ceska Lipa, Czechia, 470 01
Cesky Krumlov, Czechia, 381 01
Cesky Krumlov, Czechia, 381 27
Frydek-Mistek, Czechia, 738 01
Hodonin, Czechia, 695 01
Holesov, Czechia, 769 01
Hranice, Czechia, 753 001
Koprivnice, Czechia, 742 21
Krnov, Czechia, 794 01
Mlada Boleslav, Czechia, 293 50
Olomouc, Czechia, 775 20
Olomouc, Czechia, 779 00
Ostrava, Czechia, 702 00
Plzen, Czechia, 301 66
Prague 6, Czechia, 169 00
Praha 2, Czechia, 12808
Praha 4, Czechia, 140 00
Praha 4, Czechia, 140 46
Praha 5, Czechia, 150 00
Vlasim, Czechia, 258 01
Aalborg, Denmark, 9000
Aarhus N, Denmark, 8200
Esbjerg, Denmark, 6700
Gentofte, Denmark, 2730
Hellerup, Denmark, 2900
Herlev, Denmark, 2730
Hillerød, Denmark, DK-3400
Holbæk, Denmark, 4300
Holstebro, Denmark, DK-7500
Hvidovre, Denmark, 2650
Kolding, Denmark, 6000
København NV, Denmark, 2400
Odense C, Denmark, DK-5000
Svendborg, Denmark, 5700
Viborg, Denmark, 8800
Jyväskylä, Finland, 40620
Kajaani, Finland, 87140
Kerava, Finland, 04200
Klaukkala, Finland, 01800
Kuopio, Finland, 70100
Nurmijärvi, Finland, 01900
Oulu, Finland, 90100
Rauma, Finland, 26100
Seinäjoki, Finland, 60100
Tampere, Finland, 33520
Turku, Finland, 20521
Vantaa, Finland, 01600
Bois-guillaume, France, 76230
Boulogne Sur Mer, France, 62321
Brest, France, 29200
COLMAR Cedex, France, 68024
Dijon, France, 21000
Grenoble Cedex 9, France, 38043
Le Coudray, France, 28630
Le Creusot, France, 71200
Lyon Cedex, France, 69437
Mulhouse, France, 68051
NIMES cedex 9, France, 30029
Paris, France, 75018
Saint Herblain, France, 44093
Tourcoing, France, 59280
Vandoeuvre-les-nancy, France, 54500
Venissieux, France, 69200
Heidelberg, Baden-Württemberg, Germany, 69115
Ludwigsburg, Baden-Württemberg, Germany, 71640
Sinzheim, Baden-Württemberg, Germany, 76547
Nürnberg, Bayern, Germany, 90443
Schweinfurt, Bayern, Germany, 97421
Würzburg, Bayern, Germany, 97080
Elsterwerda, Brandenburg, Germany, 04910
Bad Homburg, Hessen, Germany, 61348
Bad König, Hessen, Germany, 64732
Frankfurt, Hessen, Germany, 60313
Frankfurt, Hessen, Germany, 60596
Göttingen, Niedersachsen, Germany, 37075
Hannover, Niedersachsen, Germany, 30625
Bad Oeynhausen, Nordrhein-Westfalen, Germany, 32545
Dortmund, Nordrhein-Westfalen, Germany, 44137
Düsseldorf, Nordrhein-Westfalen, Germany, 40210
Düsseldorf, Nordrhein-Westfalen, Germany, 40225
Essen, Nordrhein-Westfalen, Germany, 45136
Münster, Nordrhein-Westfalen, Germany, 48145
Nettetal, Nordrhein-Westfalen, Germany, 41334
Witten, Nordrhein-Westfalen, Germany, 58455
Ludwigshafen, Rheinland-Pfalz, Germany, 67059
Mainz, Rheinland-Pfalz, Germany, 55128
Magdeburg, Sachsen-Anhalt, Germany, 39120
Dresden, Sachsen, Germany, 01277
Dresden, Sachsen, Germany, 01307
Leipzig, Sachsen, Germany, 04103
Leipzig, Sachsen, Germany, 04249
Leipzig, Sachsen, Germany, 04315
Jena, Thüringen, Germany, 07747
Berlin, Germany, 10437
Berlin, Germany, 12203
Berlin, Germany, 13187
Berlin, Germany, 13347
Hamburg, Germany, 22041
Alexandroupolis, Greece, 68100
Athens, Greece, 11527
Athens, Greece, 14455
Chaidari, Greece, 12462
Larissa, Greece, 41100
Nea Ionia, Greece, 14233
Thessaloniki, Greece, 54642
Thessaloniki, Greece, 56403
Hong Kong
Hong Kong, Hong Kong
Shatin, Hong Kong
Sheung Wan, Hong Kong
Wong Tai Sin, Hong Kong
Baja, Hungary, 6500
Balatonfured, Hungary, 8230
Budapest, Hungary, 1036
Budapest, Hungary, 1042
Budapest, Hungary, 1083
Budapest, Hungary, 1088
Budapest, Hungary, 1089
Budapest, Hungary, 1134
Budapest, Hungary, 1135
Debrecen, Hungary, 4031
Eger, Hungary, 3300
Kistarcsa, Hungary, H-2143
Nyiregyhaza, Hungary, 4400
Nyiregyhaza, Hungary, 4405
Papa, Hungary, 8500
Siofok, Hungary, 8600
Szeged, Hungary, 6725
Szekesfehervar, Hungary, 8000
Szentes, Hungary, 6600
Szombathely, Hungary, 9700
Cork, Ireland
Dublin, Ireland, DUBLIN 4
Galway, Ireland
Afula, Israel, 1834111
Ashkelon, Israel, 7830604
Beer Sheva, Israel, 8410101
Haifa, Israel, 3109601
Holon, Israel, 5822012
Jerusalem, Israel, 9112001
Kfar Saba, Israel, 4428164
Nahariya, Israel, 2210001
Nahariya, Israel, 22100
Nazareth, Israel, 16100
Ramat Gan, Israel, 5262000
Rehovot, Israel, 7610001
Sakhnin, Israel, 3081000
Tel Aviv, Israel, 6203854
Tel Aviv, Israel, 6423906
Tel Aviv, Israel, 6905234
Tel Aviv, Israel, 6937947
Tiberias, Israel, 1528001
Zefat, Israel, 1311001
Zerifin, Israel, 7030000
Napoli, Campania, Italy, 80131
Bologna, Emilia-Romagna, Italy, 40138
Parma, Emilia-Romagna, Italy, 43126
Reggio Emilia, Emilia-Romagna, Italy, 42123
Genova, Liguria, Italy, 16011
Genova, Liguria, Italy, 16132
Bergamo, Lombardia, Italy, 24020
Bergamo, Lombardia, Italy, 24047
Bergamo, Lombardia, Italy, 24127
Milano, Lombardia, Italy, 20024
Milano, Lombardia, Italy, 20132
Milano, Lombardia, Italy, 20142
Milano, Lombardia, Italy, 20157
Monza Brianza, Lombardia, Italy, 20832
Torino, Piemonte, Italy, 10024
Torino, Piemonte, Italy, 10043
Cagliari, Sardegna, Italy, 09134
Sassari, Sardegna, Italy, 07026
Catania, Sicilia, Italy, 95124
Messina, Sicilia, Italy, 98125
Pisa, Toscana, Italy, 56124
Verona, Veneto, Italy, 37126
Nagoya, Aichi, Japan, 451-8511
Nagoya, Aichi, Japan, 456-0058
Nagoya, Aichi, Japan, 457-8510
Nagoya, Aichi, Japan, 460-0001
Nagoya, Aichi, Japan, 466-8650
Toyota, Aichi, Japan, 471-8513
Funabashi, Chiba, Japan, 273-8588
Ichikawa, Chiba, Japan, 272-8516
Matsuyama, Ehime, Japan, 790-0024
Matsuyama, Ehime, Japan, 791-8026
Chikushino, Fukuoka, Japan, 818-8502
Kasuga, Fukuoka, Japan, 816-0864
Kitakyushu, Fukuoka, Japan, 800-0296
Kitakyushu, Fukuoka, Japan, 802-8555
Kitakyushu, Fukuoka, Japan, 805-8508
Kitakyushu, Fukuoka, Japan, 807-0857
Shirakawa, Fukushima, Japan, 961-0005
Ogaki, Gifu, Japan, 503-8502
Maebashi, Gunma, Japan, 371-0821
Higashihiroshima, Hiroshima, Japan, 739-0041
Asahikawa, Hokkaido, Japan, 078-8234
Hakodate, Hokkaido, Japan, 041-8680
Obihiro, Hokkaido, Japan, 080-0848
Sapporo, Hokkaido, Japan, 007-0841
Kobe, Hyogo, Japan, 650-0047
Naka, Ibaraki, Japan, 311-0113
Ushiku, Ibaraki, Japan, 300-1207
Komatsu, Ishikawa, Japan, 923-8560
Sanuki, Kagawa, Japan, 769-2393
Takamatsu, Kagawa, Japan, 760-0017
Takamatsu, Kagawa, Japan, 760-0018
Atsugi, Kanagawa, Japan, 243-0035
Fujisawa, Kanagawa, Japan, 251-0041
Kamakura, Kanagawa, Japan, 247-8533
Yokohama, Kanagawa, Japan, 235-0045
Yokohama, Kanagawa, Japan, 245-8575
Yokohama, Kanagawa, Japan, 247-8581
Tamana, Kumamoto, Japan, 865-0016
Yatsushiro, Kumamoto, Japan, 866-0824
Sasebo, Nagasaki, Japan, 857-1195
Beppu, Oita, Japan, 874-0011
Yufu, Oita, Japan, 879-5593
Nakagami-gun, Okinawa, Japan, 901-2393
Shimajiri, Okinawa, Japan, 901-0493
Matsubara, Osaka, Japan, 580-0032
Suita, Osaka, Japan, 565-0862
Kawaguchi, Saitama, Japan, 332-0012
Sayama, Saitama, Japan, 350-1305
Otsu, Shiga, Japan, 520-0804
Iwata, Shizuoka, Japan, 438-8550
Oyama, Tochigi, Japan, 323-0022
Minato, Tokyo, Japan, 108-0073
Musashino, Tokyo, Japan, 180-8610
Shibuya-ku, Tokyo, Japan, 150-0002
Tacchikawa, Tokyo, Japan, 190-8531
Fukui, Japan, 910-8526
Fukui, Japan, 918-8503
Fukuoka, Japan, 811-0213
Fukuoka, Japan, 814-0180
Fukuoka, Japan, 815-8555
Kagoshima, Japan, 890-8760
Kumamoto, Japan, 861-4193
Kumamoto, Japan, 861-8520
Kumamoto, Japan, 862-0976
Nagasaki, Japan, 852-8511
Osaka, Japan, 530-0001
Osaka, Japan, 530-8480
Osaka, Japan, 543-0035
Osaka, Japan, 553-0003
Osaka, Japan, 558-8558
Saitama, Japan, 331-8577
Korea, Republic of
Wonju, Gang''weondo, Korea, Republic of, 26426
Anyang-si, Gyeonggido, Korea, Republic of, 14068
Seongnam-si, Gyeonggido, Korea, Republic of, 13620
Seoul, Seoul Teugbyeolsi, Korea, Republic of, 03080
Busan, Korea, Republic of, 49241
Daegu, Korea, Republic of, 42601
Seoul, Korea, Republic of, 02841
Seoul, Korea, Republic of, 03722
Seoul, Korea, Republic of, 05278
Seoul, Korea, Republic of, 05505
Seoul, Korea, Republic of, 06351
Seoul, Korea, Republic of, 07441
Seoul, Korea, Republic of, 110-746
Kaunas, Lithuania, LT-45217
Kaunas, Lithuania, LT-48259
Kaunas, Lithuania, LT-49449
Kaunas, Lithuania, LT-51270
Klaipeda, Lithuania, LT-92304
Utena, Lithuania, LT-28142
Vilnius, Lithuania, LT-08661
Johor Bahru, Malaysia, 80100
Kelantan, Malaysia, 15200
Kelantan, Malaysia
Kuala Lumpur, Malaysia, 59100
Pahang, Malaysia, 25100
Perak, Malaysia, 30450
Perak, Malaysia, 32040
Pulau Pinang, Malaysia, 10450
Putrajaya, Malaysia, 62250
Selangor, Malaysia, 47000
Ciudad de México, Distrito Federal, Mexico, 06729
Ciudad de México, Distrito Federal, Mexico, 11650
Ciudad de México, Distrito Federal, Mexico, 6700
México D.F., Distrito Federal, Mexico, 14080
México, D. F., Distrito Federal, Mexico, 11850
México, D. F., Distrito Federal, Mexico, 3100
Guadalajara, Jalisco, Mexico, 44600
Guadalajara, Jalisco, Mexico, 44657
Cuernavaca, Morelos, Mexico, 62250
Monterrey, Nuevo Leon, Mexico, 64460
Queretaro, Querétaro, Mexico, 76000
San Juan del Río, Querétaro, Mexico, 76800
Culiacán, Sinaloa, Mexico, 80200
Culiacán, Sinaloa, Mexico, 80230
Mazatlán, Sinaloa, Mexico, 82110
Puerto de Veracruz, Veracruz, Mexico, 91900
Xalapa, Veracruz, Mexico, 91193
Aguascalientes, Mexico, 20219
Chihuahua, Mexico, 31238
Durango, Mexico, 34000
Alkmaar, Netherlands, 1815 JD
Almere, Netherlands, 1315 RA
Amersfoort, Netherlands, 3818 TZ
Amsterdam, Netherlands, 1091 AC
Amsterdam, Netherlands, 1105 AZ
Apeldoorn, Netherlands, 7334 DZ
Breda, Netherlands, 4818 CK
Den Haag, Netherlands, 2545 CH
Eindhoven, Netherlands, 5600 PD
Geleen, Netherlands, 6162 BG
Groningen, Netherlands, 9713 GZ
Hoogeveen, Netherlands, 7909 AA
Zwijndrecht, Netherlands, 3331 LZ
New Zealand
Auckland, New Zealand, 2025
Auckland, New Zealand
Christchurch, New Zealand, 8011
Hamilton, New Zealand, 3204
Hawkes Bay, New Zealand, 4130
Palmerston North, New Zealand, 4414
Tauranga, New Zealand, 3110
Wellington, New Zealand
Hamar, Norway, 2317
Hamar, Norway
Kløfta, Norway, 2040
Kongsvinger, Norway
Kristiansand, Norway, 4604
Levanger, Norway, 7601
Lierskogen, Norway, 3420
Oslo, Norway, 0176
Oslo, Norway, 0586
Skedsmokorset, Norway, 2020
Ålesund, Norway, 6017
Iloilo City, Philippines, 5000
Marikina City, Philippines
Pasig City, Philippines, 1600
Quezon City, Philippines, 1102
Quezon City, Philippines, 1110
Quezon City, Philippines, 1112
Bialystok, Poland, 15-351
Bydgoszcz, Poland, 85-079
Chojnice, Poland, 89-600
Gdansk, Poland, 80-952
Gdynia, Poland, 81-537
Katowice, Poland, 40-040
Krakow, Poland, 30-510
Krakow, Poland, 31-156
Krakow, Poland, 31-261
Krakow, Poland, 31-559
Lodz, Poland, 90-153
Lodz, Poland, 92-213
Lodz, Poland, 94-060
Lublin, Poland, 20-538
Poznan, Poland, 60-834
Rzeszow, Poland, 35-055
Skorzewo, Poland, 60-185
Szczecin, Poland, 70-111
Torun, Poland, 87-100
Warszawa, Poland, 01-868
Warszawa, Poland
Wroclaw, Poland, 51-162
Wroclaw, Poland, 51-685
Zabrze, Poland, 41-800
Covilha, Castelo Branco, Portugal, 6200-251
Loures, Lisboa, Portugal, 2674-514
Matosinhos, Porto, Portugal, 4464-513
Funchal, Região Autónoma Da Madeira, Portugal, 9004-514
Torres Novas, Santarém, Portugal, 2350-754
Setubal, Setúbal, Portugal, 2900-446
Almada, Portugal, 2801-951
Amadora, Portugal, 2720-276
Braga, Portugal, 4710-243
Faro, Portugal, 8000-386
Leiria, Portugal, 2410-197
Lisboa, Portugal, 1069-166
Lisboa, Portugal, 1250-189
Lisboa, Portugal, 1449-005
Lisboa, Portugal, 1500-650
Porto, Portugal, 4099-001
Porto, Portugal, 4200-319
Viana do Castelo, Portugal, 4901-858
Puerto Rico
Cidra, Puerto Rico, 00739
San Juan, Puerto Rico, 00909-3004
San Juan, Puerto Rico, 00917
Alba-Iulia, Alba, Romania, 510053
Oradea, Bihor, Romania, 410519
Baia Mare, Maramures, Romania, 430222
Ploiesti, Prahova, Romania, 100179
Timisoara, Timis, Romania, 300456
Brasov, Romania, 500269
Bucuresti, Romania, 010507
Bucuresti, Romania, 010627
Bucuresti, Romania, 010825
Bucuresti, Romania, 014142
Bucuresti, Romania, 020614
Bucuresti, Romania, 031818
Bucuresti, Romania, 050538
Cluj-Napoca, Romania, 400006
Galati, Romania, 800001
Iasi, Romania, 700547
Oradea, Romania, 410159
Satu Mare, Romania, 440055
Timisoara, Romania, 300736
Russian Federation
Arkhangelsk, Russian Federation, 163001
Barnaul, Russian Federation, 656024
Chelyabinsk, Russian Federation, 454021
Irkutsk, Russian Federation, 664079
Izhevsk, Russian Federation, 426063
Kazan, Russian Federation, 420012
Kazan, Russian Federation, 420101
Kemerovo, Russian Federation, 650002
Kemerovo, Russian Federation, 650055
Kemerovo, Russian Federation, 650066
Kirov, Russian Federation, 610014
Krasnodar, Russian Federation, 350086
Krasnoyarsk, Russian Federation, 660062
Kursk, Russian Federation, 305004
Moscow, Russian Federation, 111539
Moscow, Russian Federation, 117292
Moscow, Russian Federation, 119034
Moscow, Russian Federation, 119192
Moscow, Russian Federation, 119991
Moscow, Russian Federation, 123182
Moscow, Russian Federation, 123423
Moscow, Russian Federation, 125101
Moscow, Russian Federation, 125315
Moscow, Russian Federation, 129110
Nizhny Novgorod, Russian Federation, 603018
Nizhny Novgorod, Russian Federation, 603126
Novosibirsk, Russian Federation, 630005
Novosibirsk, Russian Federation, 630047
Novosibirsk, Russian Federation, 630068
Novosibirsk, Russian Federation, 630089
Novosibirsk, Russian Federation, 630117
Omsk, Russian Federation, 644024
Omsk, Russian Federation, 644033
Omsk, Russian Federation, 644112
Orenburg, Russian Federation, 460040
Perm, Russian Federation, 614097
Saratov, Russian Federation, 410030
St. Petersburg, Russian Federation, 193312
St. Petersburg, Russian Federation, 194044
St. Petersburg, Russian Federation, 194223
St. Petersburg, Russian Federation, 194354
St. Petersburg, Russian Federation, 195067
St. Petersburg, Russian Federation, 195112
St. Petersburg, Russian Federation, 195257
St. Petersburg, Russian Federation, 197762
St. Petersburg, Russian Federation, 199226
Stavropol, Russian Federation, 355030
Syktyvkar, Russian Federation, 167981
Voronezh, Russian Federation, 394018
Voronezh, Russian Federation, 394077
Yaroslavl, Russian Federation, 150003
Yaroslavl, Russian Federation, 150062
Yekaterinburg, Russian Federation, 620102
Singapore, Singapore, 169608
Singapore, Singapore, 169609
Singapore, Singapore, 768828
Banska Bystrica, Slovakia, 974 01
Bardejov, Slovakia, 085 01
Nitra, Slovakia, 949 11
Rimavska Sobota, Slovakia, 979 01
Roznava, Slovakia, 048 01
Zilina, Slovakia, 01001
South Africa
Port Elizabeth, Eastern Cape, South Africa, 6045
Benoni, Gauteng, South Africa, 1501
Johannesburg, Gauteng, South Africa, 2198
Lenasia South, Gauteng, South Africa, 1835
Newtown, Gauteng, South Africa, 2113
Pretoria, Gauteng, South Africa, 0002
Pretoria, Gauteng, South Africa, 0181
Soweto, Gauteng, South Africa, 1818
Durban, Kwazulu-Natal, South Africa, 4030
Isipingo Rail, Kwazulu-Natal, South Africa, 4110
Tongaat, Kwazulu-Natal, South Africa, 4400
Middelburg, Mpumalanga, South Africa, 1055
Witbank, Mpumalanga, South Africa, 1035
Cape Town, Western Cape, South Africa, 7570
Cape Town, Western Cape, South Africa, 7925
Somerset West, Western Cape, South Africa, 7130
Worcester, Western Cape, South Africa, 6850
Ferrol, A Coruña, Spain, 15405
Badalona, Barcelona, Spain, 08916
L'Hospitalet de Llobregat, Barcelona, Spain, 08907
Manresa, Barcelona, Spain, 08243
Sant Joan Despi, Barcelona, Spain, 08970
Jerez de la Frontera, Cádiz, Spain, 11407
Burela, Lugo, Spain, 27880
Alcalá de Henares, Madrid, Spain, 28805
Getafe, Madrid, Spain, 28905
Sagunto, Valencia, Spain, 46520
A Coruña, Spain, 15006
Barcelona, Spain, 08003
Barcelona, Spain, 08023
Barcelona, Spain, 08025
Barcelona, Spain, 08035
Barcelona, Spain, 08036
Córdoba, Spain, 14004
Granada, Spain, 18012
Jaén, Spain, 23007
Madrid, Spain, 28007
Madrid, Spain, 28041
Málaga, Spain, 29010
Valencia, Spain, 46010
Valencia, Spain, 46014
Valencia, Spain, 46017
Valencia, Spain, 46026
Göteborg, Sweden, 413 45
Göteborg, Sweden, 413 46
Lund, Sweden, 221 85
Lund, Sweden, 222 21
Rättvik, Sweden, 795 30
Skövde, Sweden, 541 50
Stockholm, Sweden, 113 24
Stockholm, Sweden, 114 46
Stockholm, Sweden, 182 88
Uppsala, Sweden, 751 85
Uppsala, Sweden, 752 37
Örebro, Sweden, 701 85
Örebro, Sweden, 703 62
St. Gallen, Sankt Gallen, Switzerland, 9007
St. Gallen, Sankt Gallen, Switzerland, 9016
Olten, Solothurn, Switzerland, 4600
Lausanne, Vaud, Switzerland, 1011
Bern, Switzerland, 3010
Genève, Switzerland, 1205
Changhua, Taiwan, 50006
Kaohsiung, Taiwan, 833
New Taipei City, Taiwan, 220
Taichung, Taiwan, 40447
Taichung, Taiwan, 40705
Taipei, Taiwan, 100
Taipei, Taiwan, 110
Taipei, Taiwan, 11217
Taoyuan, Taiwan, 33305
Bangkok, Thailand, 10400
Bangkok, Thailand
Chiangmai, Thailand, 50200
Khon Kaen, Thailand, 40002
Ankara, Turkey
Antalya, Turkey, 07003
Antalya, Turkey, 07059
Aydin, Turkey, 09100
Istanbul, Turkey, 34303
Istanbul, Turkey, 34722
Istanbul, Turkey, 34899
Izmir, Turkey, 35100
Izmir, Turkey, 35180
Izmir, Turkey, 35540
Kayseri, Turkey, 38039
Kocaeli, Turkey, 41380
Malatya, Turkey, 44280
Sivas, Turkey, 58140
Cherkasy, Ukraine, 18009
Chernivtsi, Ukraine, 58002
Dnipro, Ukraine, 49000
Dnipro, Ukraine, 49023
Ivano-Frankivsk, Ukraine, 76008
Kharkiv, Ukraine, 61037
Kharkiv, Ukraine, 61039
Kharkiv, Ukraine, 61058
Kharkiv, Ukraine, 61070
Kiev, Ukraine, 01021
Kiev, Ukraine, 04050
Kiev, Ukraine, 04114
Kiev, Ukraine, 1601
Kyiv, Ukraine, 03037
Kyiv, Ukraine, 03049
Lviv, Ukraine, 79010
Mykolayiv, Ukraine, 54003
Ternopil, Ukraine, 46002
Vinnytsia, Ukraine, 21001
Zaporizhzhya, Ukraine, 69001
Zaporozhye, Ukraine, 69000
United Kingdom
Llanelli, Carmarthenshire, United Kingdom, SA14 8QF
Liverpool, Merseyside, United Kingdom, L7 8XP
Northampton, Northamptonshire, United Kingdom, NN1 5BD
Carshalton, Surrey, United Kingdom, SM5 1AA
Birmingham, West Midlands, United Kingdom, B15 2SQ
Chichester, West Sussex, United Kingdom, PO19 6SE
Bristol, United Kingdom, BS10 5NB
Glasgow, United Kingdom, G20 OSP
London, United Kingdom, E1 1BB
London, United Kingdom, SE5 9RS
Manchester, United Kingdom, M8 5RB
Middlesborough, United Kingdom, TS4 3BW
Ha Noi, Vietnam, 10000
Ha Noi, Vietnam
Ho Chi Minh City, Vietnam, 70000
Ho Chi Minh City, Vietnam, 84
Ho Chi Minh City, Vietnam
Sponsors and Collaborators
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Study Director: Bayer Study Director Bayer
  Study Documents (Full-Text)

Documents provided by Bayer:
Study Protocol  [PDF] March 12, 2019
Statistical Analysis Plan  [PDF] February 15, 2021

Additional Information:
Publications of Results:
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Bayer Identifier: NCT02545049    
Other Study ID Numbers: 17530
2015-000950-39 ( EudraCT Number )
First Posted: September 9, 2015    Key Record Dates
Results First Posted: April 15, 2022
Last Update Posted: April 15, 2022
Last Verified: April 2022
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: Availability of this study's data will later be determined according to Bayer's commitment to the EFPIA/PhRMA "Principles for responsible clinical trial data sharing". This pertains to scope, time point and process of data access. As such, Bayer commits to sharing upon request from qualified researcher's patient-level clinical trial data, study-level clinical trial data, and protocols from clinical trials in patients for medicines and indications approved in the US and EU as necessary for conducting legitimate research. This applies to data on new medicines and indications that have been approved by the EU and US regulatory agencies on or after January 01, 2014. Interested researchers can use to request access to anonymized patient-level data and supporting documents from clinical studies to conduct research. Information on the Bayer criteria for listing studies and other relevant information is provided in the Study sponsors section of the portal.

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Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Bayer:
Type 2 Diabetes
Kidney diseases
Additional relevant MeSH terms:
Layout table for MeSH terms
Kidney Diseases
Diabetic Nephropathies
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Urologic Diseases
Diabetes Complications