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Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
This study is currently recruiting participants.
Verified July 2017 by Pfizer
Sponsor:
Pfizer
Information provided by (Responsible Party):
Pfizer
ClinicalTrials.gov Identifier:
NCT02528188
First received: July 19, 2015
Last updated: July 7, 2017
Last verified: July 2017
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Purpose
The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis of the hips or knees.
| Condition | Intervention | Phase |
|---|---|---|
| Chronic Pain Osteoarthritis, Hip Osteoarthritis, Knee | Drug: NSAID Biological: Tanezumab 2.5 mg Biological: Tanezumab 5 mg | Phase 3 |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Participant, Investigator Primary Purpose: Treatment |
| Official Title: | A Phase 3 Randomized, Double-blind, Active-controlled, Multicenter Study Of The Long-term Safety And Efficacy Of Subcutaneous Administration Of Tanezumab In Subjects With Osteoarthritis Of The Hip Or Knee |
Resource links provided by NLM:
Further study details as provided by Pfizer:
Primary Outcome Measures:
- Incidence of a predefined composite endpoint [ Time Frame: 80 weeks ]Composite endpoint consists of adjudicated outcomes specified in protocol
- Change from Baseline in WOMAC Pain Subscale Score [ Time Frame: Week 16 ]Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain subscale
- Change from Baseline in WOMAC Physical Function Subscale Score [ Time Frame: Week 16 ]Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function subscale
- Change from Baseline in Patient's Global Assessment of Osteoarthritis [ Time Frame: Week 16 ]
Secondary Outcome Measures:
- Incidence of individual adjudication outcomes [ Time Frame: 80 Weeks ]Adjudication outcomes specified in protocol
- Incidence of all cause total joint replacements [ Time Frame: 80 weeks ]All cause total joint replacement is as defined in the protocol
- Change from Baseline in Minimum Joint Space Width of the index knee [ Time Frame: Weeks 56 and 80 ]For subjects with Kellgren Lawrence Grade 2 or 3 osteoarthritis of the index knee
- Change from Baseline in Minimum Joint Space Width of the index hip [ Time Frame: Weeks 56 and 80 ]For subjects with Kellgren Lawrence Grade 2 or 3 osteoarthritis of the index hip
- Incidence of subjects with progression of osteoarthritis in the index knee according to Bland and Altman method [ Time Frame: Weeks 56 and 80 (separately) ]For subjects with Kellgren Lawrence Grade 2 or 3 osteoarthritis of the index knee
- Incidence of subjects with progression of osteoarthritis in the index hip according to Bland and Altman method [ Time Frame: Weeks 56 and 80 (separately) ]For subjects with Kellgren Lawrence Grade 2 or 3 osteoarthritis of the index hip
- WOMAC Pain subscale change from Baseline [ Time Frame: Weeks 2, 4, 8, 24, 32, 40, 48, 56 and 64 ]
- WOMAC Physical Function subscale change from Baseline [ Time Frame: Weeks 2, 4, 8, 24, 32, 40, 48, 56 and 64 ]
- Patient's Global Assessment of Osteoarthritis change from Baseline [ Time Frame: Weeks 2, 4, 8, 16 (Japan only), 24, 32, 40, 48, 56 and 64 ]
- OMERACT OARSI responder index [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Treatment Response: Reduction in the WOMAC Pain subscale of 30%, 50%, 70% and 90% [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Cumulative distribution of percent change from Baseline in the WOMAC Pain subscale score [ Time Frame: Weeks 16, 24, and 56 ]Endpoint for summary only
- Treatment Response: Reduction in the WOMAC Physical Function subscale of 30%, 50%, 70% and 90%. [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Cumulative distribution of percent change from Baseline in the WOMAC Physical Function subscale score [ Time Frame: Weeks 16, 24, and 56 ]Endpoint for summary only
- Treatment Response: Improvement of 2 points in Patient's Global Assessment of Osteoarthritis [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Average pain score in the index joint change from Baseline [ Time Frame: Weeks 1, 2, 3, 4, 6, 8, 10, 12, 16, 20, 24, 32, 40, 48, 56 and 64 ]
- WOMAC Stiffness subscale change from Baseline [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- WOMAC Average change from Baseline [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- WOMAC Pain Subscale Item: Pain When Walking on a Flat Surface, change from Baseline [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- WOMAC Pain Subscale Item: Pain When Going Up or Down Stairs, change from Baseline [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Work Productivity and Activity Impairment Questionnaire for Osteoarthritis (WPAI:OA) impairment scores change from Baseline [ Time Frame: Weeks 16, 24, 56 and 64 ]
- EuroQol 5 Dimension (EQ 5D 5L) dimensions and overall health utility score [ Time Frame: Baseline and Weeks 8, 16, 24, 40, 56 and 64 ]
- Treatment Satisfaction Questionnaire Medicine v.II (TSQM v.II) satisfaction with effectiveness, side effects and convenience, and overall satisfaction [ Time Frame: Weeks 16 and 56 ]
- Patient Reported Treatment Impact Assessment Modified (mPRTI) [ Time Frame: Weeks 16 and 56 ]
- Incidence and Time to discontinuation due to Lack of Efficacy [ Time Frame: 56 Weeks ]
- Incidence of Rescue Medication Use [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
- Amount of Rescue Medication Taken [ Time Frame: Weeks 2, 4, 8 and 16 ]
- Health Care Resource Utilization [ Time Frame: Baseline and Weeks 64, and 80 ]
- Lower Extremity Activity Scale: change from Baseline [ Time Frame: Weeks 4, 8, 16, 24, 56 and 80 ]All subjects
- Change from Baseline in average daily minutes of physical activity [ Time Frame: Weeks 16 and 56 ]A subset of subjects
- Change from Baseline in average daily physical activity counts [ Time Frame: Weeks 16 and 56 ]A subset of subjects
- Change from Baseline in average daily minutes of moderate to vigorous physical activity [ Time Frame: Weeks 16 and 56 ]A subset of subjects
- Change from Baseline in average daily minutes of bouted (sustained) moderate to vigorous physical activity [ Time Frame: Weeks 16 and 56 ]A subset of subjects
- Change from Baseline in average daily step count [ Time Frame: Weeks 16 and 56 ]A subset of subjects
- Incidence of Subjects with Adverse Events [ Time Frame: 80 Weeks ]
- Orthostatic (supine/standing) blood pressure [ Time Frame: Baseline, Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56, 64 and 80 ]
- Survey of Autonomic Symptom scores [ Time Frame: Screening and Weeks 24, 56 and 80 ]
- Neurologic examinations [ Time Frame: Baseline, Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56, 64 and 80 ]Neuropathy Impairment Score [NIS]
- Anti tanezumab antibody levels [ Time Frame: Baseline, Weeks 8, 16, 32, 48, 56 and 80 ]
- Incidence of Physical Examination Findings [ Time Frame: Screening and Week 56 ]
- Incidence of Subjects with Clinical Laboratory Test Abnormalities [ Time Frame: Baseline, Weeks 16 and 64 ]Hematology and blood chemistry values
- Change from Baseline Sitting Blood Pressure [ Time Frame: Baseline, Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56, 64 and 80 ]
- Change from Baseline Sitting Heart Rate [ Time Frame: Baseline, Weeks 2, 4, 8, 16, 34, 32, 40, 48, 56, 64 and 80 ]
- Change from Baseline 12-lead Electrocardiogram [ Time Frame: Screening, Weeks 56 and 80 ]
- Number of Days of Rescue Medication Use [ Time Frame: Weeks 2, 4, 8, 16, 24, 32, 40, 48, 56 and 64 ]
| Estimated Enrollment: | 3000 |
| Actual Study Start Date: | July 21, 2015 |
| Estimated Study Completion Date: | March 31, 2019 |
| Estimated Primary Completion Date: | October 13, 2018 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Active Comparator: NSAID
Subcutaneous injection of placebo for tanezumab every 8 weeks plus oral NSAID (naproxen 500 mg, celecoxib 100 mg or diclofenac 75 mg) twice daily for 56 weeks
|
Drug: NSAID
Orally administered NSAID (naproxen 500 mg, celecoxib 100 mg or diclofenac 75 mg) twice daily for 56 weeks
|
|
Experimental: Tanezumab 2.5 mg
Subcutaneous injection of tanezumab 2.5 mg every 8 weeks plus oral placebo for NSAID (naproxen, celecoxib or diclofenac ER) twice daily for 56 weeks
|
Biological: Tanezumab 2.5 mg
Subcutaneous injection of tanezumab 2.5 mg every 8 weeks for 56 weeks
|
|
Experimental: Tanezumab 5 mg
Subcutaneous injection of tanezumab 5 mg every 8 weeks plus oral placebo for NSAID (naproxen, celecoxib or diclofenac) twice daily for 56 weeks
|
Biological: Tanezumab 5 mg
Subcutaneous injection of tanezumab 5 mg every 8 weeks for 56 weeks
|
Eligibility| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- A diagnosis of osteoarthritis of the index hip or knee based on American College of Rheumatology criteria with Kellgren Lawrence X ray Grade of 2 as diagnosed by the Central Reader
- Currently receiving a stable dose regimen of oral NSAID (naproxen, celecoxib, diclofenac, aceclofenac, loxoprofen, ibuprofen, meloxicam, nabumetone, sulindac or ketoprofen) as described in the protocol along with a history of insufficient pain relief from, inability to tolerate or contraindication to taking acetaminophen and, tramadol or opioid treatments. Subjects must also maintain a stabilized, protocol specified NSAID dose regimen for at least the final 2 or 3 weeks of the Screening period
- WOMAC Pain subscale score of at least 5 in the index knee or hip at Screening
- Be willing to discontinue all non study pain medications for osteoarthritis and not use prohibited pain medications throughout the duration of the study
- Female subjects of childbearing potential must agree to comply with protocol specified contraceptive requirements
Exclusion Criteria:
- Subjects exceeding protocol defined BMI or body weight limits
- History of other diseases specified in the protocol (eg, inflammatory joint diseases, crystalline diseases such as gout or pseudogout) that may involve the index joint and that could interfere with efficacy assessments
- Radiographic evidence of protocol specified bone or joint conditions in any screening radiograph as determined by the central radiology reviewer
- A history of osteonecrosis or osteoporotic fracture
- History of significant trauma or surgery to a knee, hip or shoulder within the previous year
- Planned surgical procedure during the duration of the study
- Presence of conditions (eg, fibromyaliga, radiculopathy) associated with moderate to severe pain that may confound assessments or self evaluation of osteoarthritis pain
- Signs or symptoms of carpal tunnel syndrome in the year prior to Screening
- Considered unfit for surgery based upon American Society of Anesthesiologists physical classification system for surgery grading, or subjects who would not be willing to undergo joint replacement surgery if required
- Contraindications to magnetic resonance imaging
- History of intolerance or hypersensitivity to the oral NSAID (naproxen, celecoxib or diclofenac) the subject could be randomized to receive or any of its excipients or existence of a medical condition or use of concomitant medication for which the use of this NSAID is contraindicated
- History of intolerance or hypersensitivity to acetaminophen or any of its excipients or existence of a medical condition or use of concomitant medication for which the use of acetaminophen is contraindicated
- Use of prohibited medications without the appropriate washout period prior to Screening or Initial Pain Assessment Period
- History of cancer within 5 years of Screening, except for cutaneous basal cell or squamous cell cancer resolved by excision
- Subjects with signs and symptoms of clinically significant cardiac disease as described in the protocol
- Diagnosis of a transient ischemic attack in the 6 months prior to Screening, diagnosis of stroke with residual deficits that would preclude completion of required study activities
- History, diagnosis, or signs and symptoms of clinically significant neurological disease such as but not limited to peripheral or autonomic neuropathy
- History, diagnosis, signs or symptoms of any clinically significant psychiatric disorder
- History of known alcohol, analgesic or drug abuse within 2 years of Screening
- Previous exposure to exogenous NGF or to an anti-NGF antibody
- History of allergic or anaphylactic reaction to a therapeutic or diagnostic monoclonal antibody or IgG fusion protein
- Poorly controlled hypertension as defined in the protocol or taking an antihypertensive that has not been stable for at least 1 month prior to Screening
- Evidence of protocol defined orthostatic hypotension at Screening
- Disqualifying score on the Survey of Autonomic Symptoms questionnaire at Screening
- Screening AST, ALT, serum creatinine or HbA1c values that exceed protocol defined limits
- Presence of drugs of abuse in screening urine toxicology panel
- Positive hepatitis B, hepatitis C or HIV test results indicative of current infection
- Participation in other investigational drug studies within protocol defined time limits
- Pregnant, breastfeeding or female subjects of childbearing potential who are unwilling or unable to follow protocol required contraceptive requirements
- Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that in the judgment of the investigator, would make the subject inappropriate for entry into this study
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02528188
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Please refer to this study by its ClinicalTrials.gov identifier: NCT02528188
Contacts
| Contact: Pfizer CT.gov Call Center | 1-800-718-1021 |
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Locations
| United States, Alabama | |
| Central Alabama Research | Recruiting |
| Birmingham, Alabama, United States, 35209 | |
| Achieve Clinical Research, LLC | Terminated |
| Birmingham, Alabama, United States, 35216 | |
| Alabama Clinical Therapeutics, LLC | Recruiting |
| Birmingham, Alabama, United States, 35235 | |
| Alabama Orthopaedic Surgeons | Recruiting |
| Birmingham, Alabama, United States, 35235 | |
| Rheumatology Associates of North Alabama, PC | Terminated |
| Huntsville, Alabama, United States, 35801-4414 | |
| Coastal Clinical Research, Inc. | Recruiting |
| Mobile, Alabama, United States, 36608 | |
| United States, Arizona | |
| Ferguson Family Medicine | Recruiting |
| Mesa, Arizona, United States, 85215 | |
| Arizona Research Center | Recruiting |
| Phoenix, Arizona, United States, 85023 | |
| Arizona Arthritis & Rheumatology Associates, P.C. | Recruiting |
| Phoenix, Arizona, United States, 85032 | |
| Valley Pain Consultants | Terminated |
| Scottsdale, Arizona, United States, 85254 | |
| Clinical Research Consortium | Recruiting |
| Tempe, Arizona, United States, 85283 | |
| Noble Clinical Research, LLC | Recruiting |
| Tucson, Arizona, United States, 85704 | |
| Quality of Life Medical & Research Centers, LLC | Recruiting |
| Tucson, Arizona, United States, 85712 | |
| Tucson Orthopaedic Institute - Research Center | Recruiting |
| Tucson, Arizona, United States, 85712 | |
| United States, Arkansas | |
| CHI St. Vincent Medical Group Hot Springs | Recruiting |
| Hot Springs, Arkansas, United States, 71913 | |
| Chrystal Johnson | Terminated |
| Little Rock, Arkansas, United States, 72205 | |
| KLR Business Group, Inc., dba Arkansas Clinical Research | Terminated |
| Little Rock, Arkansas, United States, 72205 | |
| Larry Watkins, MD | Terminated |
| Little Rock, Arkansas, United States, 72205 | |
| Lynn Institute of the Ozarks | Terminated |
| Little Rock, Arkansas, United States, 72205 | |
| United States, California | |
| Orange County Research Institute | Recruiting |
| Anaheim, California, United States, 92801 | |
| Advanced Research Center | Recruiting |
| Anaheim, California, United States, 92805 | |
| CITrials | Recruiting |
| Bellflower, California, United States, 90706 | |
| Osteoporosis Medical Center | Recruiting |
| Beverly Hills, California, United States, 90211 | |
| Hope Clinical Research | Recruiting |
| Canoga Park, California, United States, 91303 | |
| Med Center | Recruiting |
| Carmichael, California, United States, 95608 | |
| Core Healthcare Group | Recruiting |
| Cerritos, California, United States, 90703 | |
| Pleitez Medical Clinic | Recruiting |
| Covina, California, United States, 91723 | |
| Triwest Research Associates, LLC | Recruiting |
| El Cajon, California, United States, 92020 | |
| T. Joseph Raoof MD, INC/Encino Research Center | Recruiting |
| Encino, California, United States, 91436 | |
| San Diego Imaging Escondido | Recruiting |
| Escondido, California, United States, 92029 | |
| Med Investigations, Inc. (Administrative Office) | Recruiting |
| Fair Oaks, California, United States, 95628 | |
| Research Center of Fresno, Inc. | Terminated |
| Fresno, California, United States, 93702 | |
| Neuro-Pain Medical Center | Recruiting |
| Fresno, California, United States, 93710 | |
| Collaborative Neuroscience Network, LLC. | Terminated |
| Garden Grove, California, United States, 92845 | |
| Allied Clinical Research | Recruiting |
| Gold River, California, United States, 95670 | |
| HealthCare Partners Clinical Research, LLC. | Recruiting |
| Huntington Beach, California, United States, 92646 | |
| Marvel Clinical Research LLC | Recruiting |
| Huntington Beach, California, United States, 92647 | |
| BioSolutions Clinical Research Center | Recruiting |
| La Mesa, California, United States, 91941 | |
| eStudySite (Site & IP Shipment Only) | Recruiting |
| La Mesa, California, United States, 91942 | |
| Arthritis & Osteoporosis Medical Center | Terminated |
| La Palma, California, United States, 90723 | |
| Center For United Research, Inc. | Recruiting |
| Lakewood, California, United States, 90805 | |
| Collaborative Neuroscience Network, LLC. | Terminated |
| Long Beach, California, United States, 90806 | |
| Aeon Research, Inc. | Recruiting |
| Los Angeles, California, United States, 90010 | |
| American Institute of Research | Recruiting |
| Los Angeles, California, United States, 90017 | |
| InterMed Medical Group | Recruiting |
| Los Angeles, California, United States, 90017 | |
| IMD Medical Group | Recruiting |
| Los Angeles, California, United States, 90020 | |
| Catalina Research Institute, LLC | Recruiting |
| Montclair, California, United States, 91763 | |
| Napa Pain Institute | Recruiting |
| Napa, California, United States, 94558 | |
| Providence Clinical Research | Recruiting |
| North Hollywood, California, United States, 91606 | |
| NRC Research Institute | Recruiting |
| Orange, California, United States, 92868 | |
| Advances in Medicine | Recruiting |
| Rancho Mirage, California, United States, 92270 | |
| Probe Clinical Research Corporation | Recruiting |
| Riverside, California, United States, 92501 | |
| University of California, Davis Health System | Recruiting |
| Sacramento, California, United States, 95817 | |
| University of California, Davis Medical Center (Drug Shipment Only) | Recruiting |
| Sacramento, California, United States, 95817 | |
| Clinical Trials Research | Recruiting |
| Sacramento, California, United States, 95821 | |
| Northern California Research | Recruiting |
| Sacramento, California, United States, 95821 | |
| Center for Clinical Trials of Sacramento, Inc. | Recruiting |
| Sacramento, California, United States, 95823 | |
| Artemis Institute for Clinical Research | Recruiting |
| San Diego, California, United States, 92103 | |
| Sharp and Children's MRI Center, LLC | Recruiting |
| San Diego, California, United States, 92123 | |
| Artemis Institute for Clinical Research | Recruiting |
| San Marcos, California, United States, 92078 | |
| CITrials | Active, not recruiting |
| Santa Ana, California, United States, 92705 | |
| Syrentis Clinical Research | Terminated |
| Santa Ana, California, United States, 92705 | |
| Shariar Cohen, MD Corp. | Recruiting |
| Thousand Oaks, California, United States, 91360 | |
| Westlake Medical Research | Recruiting |
| Thousand Oaks, California, United States, 91360 | |
| Bayview Research Group | Recruiting |
| Valley Village, California, United States, 91607 | |
| Buhay & Maglunog MDS | Recruiting |
| West Covina, California, United States, 91790 | |
| Advanced Rx Clinical Research Group, Inc | Active, not recruiting |
| Westminster, California, United States, 92683 | |
| Medvin Clinical Research | Terminated |
| Whittier, California, United States, 90602 | |
| Elite Clinical Trials | Recruiting |
| Wildomar, California, United States, 92595 | |
| United States, Colorado | |
| Mountain View Clinical Research, Inc. | Recruiting |
| Denver, Colorado, United States, 80209 | |
| Mountain View Clinical Research, Inc | Recruiting |
| Denver, Colorado, United States, 80209 | |
| United States, Connecticut | |
| Clinical Research Center of CT | Recruiting |
| Danbury, Connecticut, United States, 06810 | |
| Stamford Therapeutics Consortium | Recruiting |
| Stamford, Connecticut, United States, 06905 | |
| New England Research Associates, LLC | Recruiting |
| Trumbull, Connecticut, United States, 06611 | |
| United States, Delaware | |
| Rheumatology Consultants of Delaware dba Delaware Arthritis | Recruiting |
| Lewes, Delaware, United States, 19958 | |
| Javed Rheumatology Associates, Inc. | Recruiting |
| Newark, Delaware, United States, 19713 | |
| United States, Florida | |
| JEM Research Institute | Recruiting |
| Atlantis, Florida, United States, 33462 | |
| Arthritis and Rheumatic Disease Specialties | Recruiting |
| Aventura, Florida, United States, 33180 | |
| RASF-Clinical Research, Inc | Recruiting |
| Boca Raton, Florida, United States, 33486 | |
| Orthopedic Research Institute | Recruiting |
| Boynton Beach, Florida, United States, 33472 | |
| Meridien Research | Recruiting |
| Brooksville, Florida, United States, 34601 | |
| Orthopaedic Associates of West Florida | Recruiting |
| Clearwater, Florida, United States, 33756 | |
| Tampa Bay Medical Research | Recruiting |
| Clearwater, Florida, United States, 33761 | |
| Midland Florida Clinical Research Center, LLC | Terminated |
| DeLand, Florida, United States, 32720 | |
| S&W Clinical Research | Recruiting |
| Fort Lauderdale, Florida, United States, 33306 | |
| Centre for Rheumatology, Immunology and Arthritis | Recruiting |
| Fort Lauderdale, Florida, United States, 33309 | |
| Clinical Physiology Associates | Recruiting |
| Fort Myers, Florida, United States, 33912 | |
| IMA | Recruiting |
| Fort Myers, Florida, United States, 33912 | |
| SIMED Arthritis Center | Recruiting |
| Gainesville, Florida, United States, 32607 | |
| Southeastern Integrated Medical PL d/b/a Florida Medical Research Institute | Recruiting |
| Gainesville, Florida, United States, 32607 | |
| Rivero Diagnostic Center | Recruiting |
| Hialeah, Florida, United States, 33012 | |
| South Florida Clinical Trials | Recruiting |
| Hialeah, Florida, United States, 33016 | |
| Pines Clinical Research Inc. | Recruiting |
| Hollywood, Florida, United States, 33024 | |
| Jacksonville Center for Clinical Research | Recruiting |
| Jacksonville, Florida, United States, 32216 | |
| Care Partners Clinical Research | Recruiting |
| Jacksonville, Florida, United States, 32218 | |
| Clinical Neuroscience Solutions, Inc. | Recruiting |
| Jacksonville, Florida, United States, 32256 | |
| Care Partners Clinical Research | Recruiting |
| Jacksonville, Florida, United States, 32277 | |
| Sunrise Medical Research, Inc. | Recruiting |
| Lauderdale Lakes, Florida, United States, 33319 | |
| Pharmax Research Clinic, Inc. | Recruiting |
| Miami, Florida, United States, 33126 | |
| Clintex Research Group | Recruiting |
| Miami, Florida, United States, 33135 | |
| Digital Medical Diagnostic (Diagnostic Center) | Recruiting |
| Miami, Florida, United States, 33144 | |
| Columbus Clinical Services LLc | Recruiting |
| Miami, Florida, United States, 33165 | |
| Center for Arthritis and Rheumatic Diseases | Terminated |
| Miami, Florida, United States, 33173 | |
| New Horizon Research Center | Recruiting |
| Miami, Florida, United States, 33175 | |
| International Research Associates, LLC | Recruiting |
| Miami, Florida, United States, 33183 | |
| M&M Medical Center, Inc. | Recruiting |
| Miami, Florida, United States, 33185 | |
| Quality Research & Medical Center LLC | Active, not recruiting |
| Miami, Florida, United States, 33186 | |
| American Family Medical | Recruiting |
| Ocala, Florida, United States, 34471 | |
| Renstar Medical Research | Recruiting |
| Ocala, Florida, United States, 34471 | |
| Sensible Healthcare, LLC. | Recruiting |
| Ocoee, Florida, United States, 34761 | |
| Journey Research, Inc. | Recruiting |
| Oldsmar, Florida, United States, 34677 | |
| Sunshine Research Center | Recruiting |
| Opa-locka, Florida, United States, 33054 | |
| Omega Research Consultants, LLC | Recruiting |
| Orlando, Florida, United States, 32804 | |
| Compass Research, LLC | Recruiting |
| Orlando, Florida, United States, 32806 | |
| Rheumatology Associates of Central Florida, P.A. | Terminated |
| Orlando, Florida, United States, 32806 | |
| Oviedo Medical Research, LLC | Recruiting |
| Oviedo, Florida, United States, 32765 | |
| Pensacola Research Consultants, Inc. | Recruiting |
| Pensacola, Florida, United States, 32503 | |
| Sacred Heart Orthopedics | Recruiting |
| Pensacola, Florida, United States, 32503 | |
| Orthopeadic Center of South Florida | Recruiting |
| Plantation, Florida, United States, 33324 | |
| St. Johns Center for Clinical Research | Recruiting |
| Ponte Vedra, Florida, United States, 32081 | |
| Progressive Medical Research | Recruiting |
| Port Orange, Florida, United States, 32127 | |
| Accord Clinical Research, LLC | Recruiting |
| Port Orange, Florida, United States, 32129 | |
| Meridien Research | Recruiting |
| Saint Petersburg, Florida, United States, 33709 | |
| Gulfcoast Research Institute, LLC | Recruiting |
| Sarasota, Florida, United States, 34232-6028 | |
| Phoenix Clinical Research, LLC. | Recruiting |
| Tamarac, Florida, United States, 33321 | |
| Clinical Research of West Florida, Inc. | Recruiting |
| Tampa, Florida, United States, 33603 | |
| Stedman Clinical Trials | Recruiting |
| Tampa, Florida, United States, 33613 | |
| BayCare Medical Group, Inc | Recruiting |
| Tampa, Florida, United States, 33614 | |
| Compass Research North LLC | Terminated |
| The Villages, Florida, United States, 32162 | |
| Palm Beach Research Center | Terminated |
| West Palm Beach, Florida, United States, 33409 | |
| United States, Georgia | |
| Atlanta Center for Medical Research | Recruiting |
| Atlanta, Georgia, United States, 30331 | |
| Perimeter Institute for Clinical Research, Inc. DBA:/PICR Clinic | Terminated |
| Atlanta, Georgia, United States, 30338 | |
| Masters of Clinical Research, Inc. | Recruiting |
| Augusta, Georgia, United States, 30909 | |
| River Birch Research Alliance, LLC | Recruiting |
| Blue Ridge, Georgia, United States, 30513 | |
| Arthritis Center of North Georgia-Division of Low Country Rheumatology, PA | Recruiting |
| Gainesville, Georgia, United States, 30501 | |
| Center for Advanced Research & Education | Terminated |
| Gainesville, Georgia, United States, 30501 | |
| Drug Studies America | Recruiting |
| Marietta, Georgia, United States, 30060 | |
| Better Health Clinical Research, Inc. | Recruiting |
| Newnan, Georgia, United States, 30265 | |
| Atlanta Orthopaedic Institute, LLC | Recruiting |
| Stockbridge, Georgia, United States, 30281 | |
| Herman Clinical Research, LLC | Recruiting |
| Suwanee, Georgia, United States, 30024 | |
| North Georgia Clinical Research | Recruiting |
| Woodstock, Georgia, United States, 30189 | |
| North Georgia Internal Medicine | Recruiting |
| Woodstock, Georgia, United States, 30189 | |
| United States, Hawaii | |
| East-West Medical Research Institute | Recruiting |
| Honolulu, Hawaii, United States, 96814 | |
| United States, Idaho | |
| Idaho Sports Medicine Institute | Terminated |
| Boise, Idaho, United States, 83706 | |
| Injury Care Research, LLC | Recruiting |
| Boise, Idaho, United States, 83713 | |
| Institute Of Arthritis Research | Terminated |
| Idaho Falls, Idaho, United States, 83404 | |
| Advanced Clinical Research | Terminated |
| Meridian, Idaho, United States, 83642 | |
| Exodus Pain Clinic | Recruiting |
| Meridian, Idaho, United States, 83642 | |
| United States, Illinois | |
| Medex Healthcare Research, Inc. | Recruiting |
| Chicago, Illinois, United States, 60602 | |
| Northwestern Memorial Hospital-Arkes Pavilion, Diagnostic Testing Center | Recruiting |
| Chicago, Illinois, United States, 60611 | |
| Northwestern University Feinberg School of Medicine-Drug Shipment | Recruiting |
| Chicago, Illinois, United States, 60611 | |
| Rush University Medical Center (Drug Shipment Address Only) | Recruiting |
| Chicago, Illinois, United States, 60612 | |
| Rush University Medical Center | Recruiting |
| Chicago, Illinois, United States, 60612 | |
| Chicago Clinical Research Institute Inc. | Recruiting |
| Chicago, Illinois, United States, 60616 | |
| Great Lakes Clinical Trials | Active, not recruiting |
| Chicago, Illinois, United States, 60640 | |
| Southwest Center for Health Joints, S.C. | Recruiting |
| Oak Lawn, Illinois, United States, 60453 | |
| Methodist Research Administration Office (Drug shipment only) | Recruiting |
| Peoria, Illinois, United States, 61602 | |
| UnityPoint Clinic Rheumatology | Recruiting |
| Peoria, Illinois, United States, 61602 | |
| Methodist Medical Center of Illinois | Recruiting |
| Peoria, Illinois, United States, 61636 | |
| OrthoIllinois | Recruiting |
| Rockford, Illinois, United States, 61114 | |
| United States, Indiana | |
| MediSphere Medical Research Center, LLC | Recruiting |
| Evansville, Indiana, United States, 47714 | |
| Buynak Clinical Research, P.C. | Recruiting |
| Valparaiso, Indiana, United States, 46383 | |
| United States, Kansas | |
| Mid-America Physiatrists, P.A. | Recruiting |
| Overland Park, Kansas, United States, 66210 | |
| Phoenix Medical Research, Inc. | Recruiting |
| Prairie Village, Kansas, United States, 66208 | |
| Professional Research Nework of Kansas, LLC | Recruiting |
| Wichita, Kansas, United States, 67205-1138 | |
| Heartland Research Associates, LLC | Terminated |
| Wichita, Kansas, United States, 67207 | |
| United States, Kentucky | |
| Otri-Med Corporation | Recruiting |
| Edgewood, Kentucky, United States, 41017 | |
| Central Kentucky Research Associates, Inc. | Recruiting |
| Lexington, Kentucky, United States, 40509 | |
| United States, Louisiana | |
| Baton Rouge General Medical Center-Internal Medicine Clinic | Terminated |
| Baton Rouge, Louisiana, United States, 70806 | |
| Baton Rouge General Medical Center-Midcity | Terminated |
| Baton Rouge, Louisiana, United States, 70806 | |
| Baton Rouge General Medical Center-Bluebonnet | Terminated |
| Baton Rouge, Louisiana, United States, 70809 | |
| Baton Rouge General Medical Center-Clinical Trials Office | Terminated |
| Baton Rouge, Louisiana, United States, 70809 | |
| Centex Studies, Inc. | Recruiting |
| Lake Charles, Louisiana, United States, 70601 | |
| United States, Maryland | |
| Klein & Associates, M.D., P.A. | Terminated |
| Cumberland, Maryland, United States, 21502 | |
| Arthritis Treatment Center | Recruiting |
| Frederick, Maryland, United States, 21702 | |
| Klein & Associates, M.D., P.A. | Recruiting |
| Hagerstown, Maryland, United States, 21740 | |
| The Center for Rheumatology and Bone Research | Recruiting |
| Wheaton, Maryland, United States, 20902 | |
| United States, Massachusetts | |
| Beacon Clinical Research, LLC | Recruiting |
| Quincy, Massachusetts, United States, 02169 | |
| MedVadis Research Corporation | Recruiting |
| Watertown, Massachusetts, United States, 02472 | |
| United States, Michigan | |
| Great Lakes Research Group, Incorporated | Recruiting |
| Bay City, Michigan, United States, 48706 | |
| Medex Research Institute, LLC | Recruiting |
| Caro, Michigan, United States, 48723 | |
| Orthopaedic Associates of Michigan | Recruiting |
| Grand Rapids, Michigan, United States, 49525 | |
| June D.O. PC | Recruiting |
| Lansing, Michigan, United States, 48910 | |
| Great Lakes Research Group | Terminated |
| Pinconning, Michigan, United States, 48650 | |
| Michigan Orthopaedic Spine Surgeons | Recruiting |
| Rochester Hills, Michigan, United States, 48307 | |
| Medical Research Associates Inc. | Recruiting |
| Traverse City, Michigan, United States, 49686 | |
| Oakland Medical Research Center | Terminated |
| Troy, Michigan, United States, 48085 | |
| United States, Mississippi | |
| Olive Branch Family Medical Center | Recruiting |
| Olive Branch, Mississippi, United States, 38654 | |
| United States, Missouri | |
| University of Missouri Health Care-Investigational Pharmacy | Recruiting |
| Columbia, Missouri, United States, 65212 | |
| University of Missouri Health Care | Recruiting |
| Columbia, Missouri, United States, 65212 | |
| University of Missouri School of Medicine- Clinical Research Center | Recruiting |
| Columbia, Missouri, United States, 65212 | |
| Medex Healthcare Research, Inc. | Terminated |
| Saint Louis, Missouri, United States, 63117 | |
| Advance Clinical Research, Inc. | Recruiting |
| Saint Louis, Missouri, United States, 63128 | |
| United States, Nebraska | |
| Physician Research Collaboration, LLC | Recruiting |
| Lincoln, Nebraska, United States, 68516 | |
| United States, Nevada | |
| Impact Clinical Trials | Recruiting |
| Las Vegas, Nevada, United States, 89106 | |
| Clinical Research Consortium | Recruiting |
| Las Vegas, Nevada, United States, 89119 | |
| Office of Robert P. Kaplan, DO | Recruiting |
| Las Vegas, Nevada, United States, 89119 | |
| Advanced Biomedical Research of America | Recruiting |
| Las Vegas, Nevada, United States, 89123 | |
| G. Timothy Kelly, MD | Terminated |
| Las Vegas, Nevada, United States, 89128 | |
| Office of Dr. Stephen H. Miller, MD | Recruiting |
| Las Vegas, Nevada, United States, 89144 | |
| United States, New Hampshire | |
| ActivMed Practices & Research, Inc. | Recruiting |
| Portsmouth, New Hampshire, United States, 03801 | |
| United States, New Jersey | |
| Ocean Rheumatology, PA | Recruiting |
| Toms River, New Jersey, United States, 08755 | |
| Premier Research | Recruiting |
| Trenton, New Jersey, United States, 08611 | |
| Arthritis, Rheumatic and Back Disease Associates, PA | Recruiting |
| Voorhees, New Jersey, United States, 08043 | |
| United States, New Mexico | |
| Albuquerque Clinical Trials, Inc. | Recruiting |
| Albuquerque, New Mexico, United States, 87102 | |
| New Mexico Clinical Research & Osteoporosis Center, Inc. | Recruiting |
| Albuquerque, New Mexico, United States, 87106 | |
| Lovelace Scientific Resources Inc. | Recruiting |
| Albuquerque, New Mexico, United States, 87108 | |
| United States, New York | |
| Weill Cornell Physicians at Brooklyn Heights | Recruiting |
| Brooklyn, New York, United States, 11201 | |
| Drug Trials Brooklyn | Recruiting |
| Brooklyn, New York, United States, 11230 | |
| SPRI Clinical Trials, LLC | Recruiting |
| Brooklyn, New York, United States, 11235 | |
| Drug Trials America | Recruiting |
| Hartsdale, New York, United States, 10530 | |
| Hartsdale Imaging | Recruiting |
| Hartsdale, New York, United States, 10530 | |
| NYU Langone Arena Oncology, Laura and Issac Perlmutter Cancer Center, Infusion Center | Recruiting |
| Lake Success, New York, United States, 11042 | |
| NYU Langone Arena Oncology, Laura and Issac Perlmutter Cancer Center | Recruiting |
| Lake Success, New York, United States, 11042 | |
| NYU Langone Rheumatology Associates Long Island | Recruiting |
| Lake Success, New York, United States, 11042 | |
| Lenox Hill Radiology | Recruiting |
| New York, New York, United States, 10016 | |
| Manhattan Medical Research Practice PLLC | Recruiting |
| New York, New York, United States, 10016 | |
| The Medical Research Network, LLC | Terminated |
| New York, New York, United States, 10128 | |
| AAIR Research Center | Recruiting |
| Rochester, New York, United States, 14618 | |
| Westchester Imaging | Recruiting |
| White Plains, New York, United States, 10605 | |
| Upstate Clinical Research Associates, LLC | Recruiting |
| Williamsville, New York, United States, 14221 | |
| United States, North Carolina | |
| Waterway Primary Care, LLC dba Calabash Medical Center | Recruiting |
| Calabash, North Carolina, United States, 28467 | |
| Northstate Clinical Research, PLLC | Recruiting |
| Lenoir, North Carolina, United States, 28645 | |
| Wake Internal Medicine Consultants, Inc | Terminated |
| Raleigh, North Carolina, United States, 27612 | |
| Wake Research Associates, LLC | Terminated |
| Raleigh, North Carolina, United States, 27612 | |
| Tabor City Family Medicine | Recruiting |
| Tabor City, North Carolina, United States, 28463 | |
| The Center for Clinical Research | Recruiting |
| Winston-Salem, North Carolina, United States, 27103 | |
| United States, North Dakota | |
| Lillestol Research, LLC | Terminated |
| Fargo, North Dakota, United States, 58103 | |
| Plains Clinical Research Center, LLC | Recruiting |
| Fargo, North Dakota, United States, 58104 | |
| United States, Ohio | |
| Valley Medical Research/Valley Medical Primary Care | Terminated |
| Centerville, Ohio, United States, 45459 | |
| Hightop Medical Research Center | Recruiting |
| Cincinnati, Ohio, United States, 45224 | |
| New Horizons Clinical Research | Recruiting |
| Cincinnati, Ohio, United States, 45242 | |
| CTI Clinical Research Center | Terminated |
| Cincinnati, Ohio, United States, 45255 | |
| Cleveland Clinic | Not yet recruiting |
| Cleveland, Ohio, United States, 44195 | |
| Aventiv Research Inc. | Recruiting |
| Columbus, Ohio, United States, 43213 | |
| Remington-Davis, Incorporated | Recruiting |
| Columbus, Ohio, United States, 43215 | |
| Optimed Research LTD | Recruiting |
| Columbus, Ohio, United States, 43235 | |
| Dayton Clinical Research | Recruiting |
| Dayton, Ohio, United States, 45406 | |
| PriMed Clinical Research | Recruiting |
| Dayton, Ohio, United States, 45419 | |
| AC Clinical Research | Recruiting |
| Tiffin, Ohio, United States, 44883 | |
| Glendale Medical Center | Not yet recruiting |
| Toledo, Ohio, United States, 43614 | |
| Bone Joint & Spine Surgeons, Inc. | Recruiting |
| Toledo, Ohio, United States, 43623 | |
| United States, Oklahoma | |
| Health Research of Oklahoma | Recruiting |
| Oklahoma City, Oklahoma, United States, 73103 | |
| Lynn Health Science Institute | Recruiting |
| Oklahoma City, Oklahoma, United States, 73112 | |
| United States, Pennsylvania | |
| University Orthopedics Center | Terminated |
| Altoona, Pennsylvania, United States, 16602 | |
| Heritage Valley Medical Group, Inc. | Terminated |
| Beaver, Pennsylvania, United States, 15009 | |
| Brandywine Clinical Research | Recruiting |
| Downingtown, Pennsylvania, United States, 19335 | |
| Altoona Center for Clinical Research | Recruiting |
| Duncansville, Pennsylvania, United States, 16635 | |
| The Clinical Trial Center LLC | Recruiting |
| Jenkintown, Pennsylvania, United States, 19046 | |
| Founders Research Corporation | Recruiting |
| Philadelphia, Pennsylvania, United States, 19152 | |
| The Arthritis Group | Terminated |
| Philadelphia, Pennsylvania, United States, 19152 | |
| Clinical Research Center of Reading, LLC | Terminated |
| Wyomissing, Pennsylvania, United States, 19610 | |
| United States, South Carolina | |
| North Myrtle Beach Family Practice | Terminated |
| North Myrtle Beach, South Carolina, United States, 29582 | |
| United States, Tennessee | |
| Clinical Research Solutions | Terminated |
| Jackson, Tennessee, United States, 38305 | |
| Physicians Quality Care | Terminated |
| Jackson, Tennessee, United States, 38305 | |
| PMG Research, Inc. d/b/a PMG Research of Knoxville | Recruiting |
| Jefferson City, Tennessee, United States, 37760 | |
| PCET Research Center, LLC | Terminated |
| Knoxville, Tennessee, United States, 37909 | |
| United States, Texas | |
| ARC Clinical Research at Wilson Parke | Recruiting |
| Austin, Texas, United States, 78726 | |
| Tekton Research, Inc. | Terminated |
| Austin, Texas, United States, 78745 | |
| Urgent Care MD's | Terminated |
| Baytown, Texas, United States, 77521 | |
| Texas Orthopedic Specialists, PLLC | Recruiting |
| Bedford, Texas, United States, 76021 | |
| Galenos Research | Recruiting |
| Dallas, Texas, United States, 75251 | |
| Abigail R. Neiman, MD, PA | Recruiting |
| Houston, Texas, United States, 77024 | |
| Advances in Health | Recruiting |
| Houston, Texas, United States, 77030 | |
| Mercury Clinical Research, Inc. | Recruiting |
| Houston, Texas, United States, 77036 | |
| Centex Studies, Inc. | Recruiting |
| Houston, Texas, United States, 77058 | |
| Memorial Pulmonology | Terminated |
| Houston, Texas, United States, 77079 | |
| BI Research Center | Recruiting |
| Houston, Texas, United States, 77084 | |
| Clinical Investigations of Texas, LLC | Recruiting |
| Plano, Texas, United States, 75075 | |
| ClinRX Research | Recruiting |
| Richardson, Texas, United States, 75080 | |
| Quality Research, Inc. | Recruiting |
| San Antonio, Texas, United States, 78209 | |
| Lee Medical Associates PA | Recruiting |
| San Antonio, Texas, United States, 78213 | |
| Progressive Clinical Research, PA | Recruiting |
| San Antonio, Texas, United States, 78213 | |
| Sun Research Institute | Recruiting |
| San Antonio, Texas, United States, 78215 | |
| Panacea Clinical Research | Recruiting |
| San Antonio, Texas, United States, 78228 | |
| Accurate Clinical Research Inc. | Active, not recruiting |
| San Antonio, Texas, United States, 78229 | |
| Diagnostics Research Group | Terminated |
| San Antonio, Texas, United States, 78229 | |
| Victorium Clinical Research | Recruiting |
| San Antonio, Texas, United States, 78231 | |
| DCT-Stone Oak, LLC dba Discovery Clinical Trials | Recruiting |
| San Antonio, Texas, United States, 78258 | |
| South Texas Radiology Imaging Centers | Recruiting |
| San Antonio, Texas, United States, 78258 | |
| Oakbend Medical Center | Terminated |
| Sugar Land, Texas, United States, 77479 | |
| ClinPoint Trials | Recruiting |
| Waxahachie, Texas, United States, 75165 | |
| Texas Gulf Coast Medical Group | Recruiting |
| Webster, Texas, United States, 77598 | |
| Clinics of North Texas | Recruiting |
| Wichita Falls, Texas, United States, 76302 | |
| Grayline Clinical Drug Trials | Recruiting |
| Wichita Falls, Texas, United States, 76309 | |
| United States, Utah | |
| Granger Medical Clinic-Riverton | Terminated |
| Riverton, Utah, United States, 84065 | |
| United States, Virginia | |
| Millennium Clinical Trials, LLC | Recruiting |
| Arlington, Virginia, United States, 22207 | |
| Charlottesville Medical Research Center, LLC | Terminated |
| Charlottesville, Virginia, United States, 22911 | |
| National Clinical Research-Norfolk, Inc. | Terminated |
| Norfolk, Virginia, United States, 23502 | |
| United States, Washington | |
| Northwest Clinical Research Center | Recruiting |
| Bellevue, Washington, United States, 98007 | |
| Optimed Research, LTD | Recruiting |
| Bellingham, Washington, United States, 98225 | |
| Swedish Medical Center Investigational Drug Services Pharmacy | Terminated |
| Seattle, Washington, United States, 98104 | |
| Seattle Rheumatology Associates | Terminated |
| Seattle, Washington, United States, 98122 | |
| Swedish Medical Center | Terminated |
| Seattle, Washington, United States, 98122 | |
| Australia, New South Wales | |
| Genesis Research Services | Recruiting |
| Broadmeadow, New South Wales, Australia, 2292 | |
| Hunter Imaging Group | Recruiting |
| Cardiff, New South Wales, Australia, 2285 | |
| Optimus Clinical Research Pty Ltd | Terminated |
| Kogarah, New South Wales, Australia, 2217 | |
| Southern Radiology | Terminated |
| Miranda, New South Wales, Australia, 2228 | |
| Royal Hospital for Women | Recruiting |
| Randwick, New South Wales, Australia, 2031 | |
| Castlereagh Imaging | Active, not recruiting |
| St Leonards, New South Wales, Australia, 2065 | |
| Royal North Shore Hospital | Active, not recruiting |
| St Leonards, New South Wales, Australia, 2065 | |
| Australian Clinical Research Network | Recruiting |
| Sydney, New South Wales, Australia, 2035 | |
| Spectrum Medical Imaging | Recruiting |
| Sydney, New South Wales, Australia, 2035 | |
| Australia, Queensland | |
| AusTrials Pty Ltd | Recruiting |
| Sherwood, Queensland, Australia, 4075 | |
| Australia, South Australia | |
| CMAX-a division of IDT Australia Limited | Recruiting |
| Adelaide, South Australia, Australia, 5000 | |
| Royal Adelaide Hospital Pharmacy | Recruiting |
| Adelaide, South Australia, Australia, 5000 | |
| Bensons Radiology | Recruiting |
| North Adelaide, South Australia, Australia, 5006 | |
| Australia, Victoria | |
| Capital Radiology-Malvern | Recruiting |
| Melbourne, Victoria, Australia, 3144 | |
| Emeritus Research | Recruiting |
| Melbourne, Victoria, Australia, 3145 | |
| Capital Radiology-Clayton | Recruiting |
| Melbourne, Victoria, Australia, 3168 | |
| Australia, Western Australia | |
| SKG Radiology Hollywood | Recruiting |
| Nedlands, Western Australia, Australia, 6009 | |
| RK Will Pty Ltd | Recruiting |
| Victoria Park, Western Australia, Australia, 6100 | |
| Brazil | |
| CEDOES - Centro de Diagnostico e Pesquisa as Osteoporose do Espirito Santo Ltda | Not yet recruiting |
| Vitoria, Espirito Santo, Brazil, 29055-450 | |
| CMIP-Centro Mineiro de Pesquisa LTDA | Not yet recruiting |
| Juiz de Fora, Minas Gerais, Brazil, 36010-570 | |
| CETI -Centro de Estudos em Terapias lnovadoras | Not yet recruiting |
| Curitiba, Parana, Brazil, 80030-110 | |
| Hospital de Clinicas de Porto Alegre | Not yet recruiting |
| Porto Alegre, Rio Grande Do Sul, Brazil, 90035-903 | |
| CCBR - Centro de Pesquisas e Analises Clinicas LTDA | Not yet recruiting |
| Rio De Janeiro, RJ, Brazil, 22271-100 | |
| CEPIC - Centro Paulista de Investigacao Clinica e Servicos Medicos Ltda | Not yet recruiting |
| Sao Paulo, SP, Brazil, 04266-010 | |
| Associacao de Assitencia a Crianca Deficientes-AACD | Not yet recruiting |
| Sao Paulo, Brazil, 04032-060 | |
| Hospital Israelita Albert Einstein | Not yet recruiting |
| Sao Paulo, Brazil, 05652-000 | |
| Bulgaria | |
| Diagnostic Consultative Center "Sveti Georgi" EOOD | Recruiting |
| Plovdiv, Bulgaria, 4000 | |
| Medical Center "Health for all" - EOOD | Recruiting |
| Plovdiv, Bulgaria, 4000 | |
| UMHAT Kaspela - EOOD | Recruiting |
| Plovdiv, Bulgaria, 4001 | |
| UMHT Kaspela - EOOD Rheumatology Clinic | Recruiting |
| Plovdiv, Bulgaria, 4001 | |
| Military Medical Acadamy - MHAT Sofia | Recruiting |
| Sofia, Bulgaria, 1431 | |
| Diagnostic Consultative Center 17 Sofia EOOD | Recruiting |
| Sofia, Bulgaria, 1505 | |
| UMHAT Sveti Ivan Rilski- EAD | Recruiting |
| Sofia, Bulgaria, 1612 | |
| UMHAT "Sofiamed" OOD, Block 2 | Recruiting |
| Sofia, Bulgaria, 1750 | |
| Colombia | |
| Centro Integral de Reumatologia Reumalab S.A.S. | Not yet recruiting |
| Medellin, Antioquia, Colombia, 05001000 | |
| Hospital Pablo Tobon Uribe | Not yet recruiting |
| Medellin, Antioquia, Colombia, 050034 | |
| Centro de Investigacion en Reumatologia y Especialidades Medicas SAS CIREEM SAS | Not yet recruiting |
| Bogota, Bogota Dc, Colombia, 110221 | |
| Medicity S.A.S | Not yet recruiting |
| Bucaramanga, Santander, Colombia, 680003 | |
| Croatia | |
| Klinicki Bolnicki Centar Rijeka | Recruiting |
| Rijeka, Croatia, 51000 | |
| Medicinski centar Kuna&Peric | Recruiting |
| Zagreb, Croatia, 10000 | |
| Japan | |
| National Hospital Organization Toyohashi Medical Center | Recruiting |
| Toyohashi, Aichi, Japan, 440-8510 | |
| Funabashi Municipal Medical Center | Recruiting |
| Funabashi, Chiba, Japan, 273-8588 | |
| Matsudo City Hospital | Recruiting |
| Matsudo, Chiba, Japan, 271-8511 | |
| Kanbara Clinic | Active, not recruiting |
| Kitakyushu, Fukuoka, Japan, 806-0026 | |
| Hidaka Orthopedic Hospital | Terminated |
| Kurume, Fukuoka, Japan, 830-0053 | |
| Obase Hospital | Recruiting |
| Miyako-gun, Fukuoka, Japan, 800-0344 | |
| Himeno Hospital | Recruiting |
| Yamegun, Fukuoka, Japan, 834-0115 | |
| Ikeda Kinen Hospital | Not yet recruiting |
| Sukagawa, Fukushima, Japan, 962-0001 | |
| Zenshukai Hospital | Recruiting |
| Maebashi, Gunma, Japan, 379-2115 | |
| Mazda Hospital | Recruiting |
| Aki-gun, Hiroshima, Japan, 735-8585 | |
| Medical Corporation Okimoto Clinic | Recruiting |
| Kure, Hiroshima, Japan, 734-0304 | |
| Medical Corporation Emu Emukai, Matterhorn Rehabilitation Hospital | Recruiting |
| Kure, Hiroshima, Japan, 737-0046 | |
| Takahashi Orthopedics Clinic | Recruiting |
| Chitose, Hokkaido, Japan, 066-0062 | |
| Obihiro Orthopaedic Hospital | Recruiting |
| Obihiro, Hokkaido, Japan, 080-0802 | |
| Okubo Hospital | Recruiting |
| Akashi, Hyogo, Japan, 674-0051 | |
| Omuro Orthopedic Clinic | Recruiting |
| Himeji, Hyogo, Japan, 670-0976 | |
| Medical corporate corporation hoshikai Onishi medical clinic | Recruiting |
| Kako-gun, Hyogo, Japan, 675-1115 | |
| Kobe Red Cross Hospital | Recruiting |
| Kobe, Hyogo, Japan, 651-0073 | |
| Mito Saiseikai General Hospital | Recruiting |
| Mito, Ibaraki, Japan, 311-4198 | |
| National Hospital Organization Kanazawa Medical Center | Recruiting |
| Kanazawa, Ishikawa, Japan, 920-8650 | |
| Kokan Clinic | Recruiting |
| Kawasaki, Kanagawa, Japan, 210-0852 | |
| Misugikai Medical Corporation Otokoyama Hospital | Recruiting |
| Yawata, Kyoto, Japan, 614-8366 | |
| Nakajo Orthopedic Clinic | Recruiting |
| Sendai, Miyagi, Japan, 983-0862 | |
| Marunouchi Hospital | Recruiting |
| Matsumoto, Nagano, Japan, 390-8601 | |
| Oita University Hospital | Recruiting |
| Yufu, Oita, Japan, 879-5593 | |
| Sobajima Clinic/Orthopedics | Recruiting |
| Higashiosaka, Osaka, Japan, 577-0011 | |
| Rinku General Medical Center | Recruiting |
| Izumisano, Osaka, Japan, 598-8577 | |
| Kishiwada Tokushukai Hospital | Recruiting |
| Kishiwada, Osaka, Japan, 596-8522 | |
| Osaka saiseikai nakatsu hospital | Recruiting |
| Osaka-shi, Osaka, Japan, 530-0012 | |
| Osaka University Hospital | Recruiting |
| Suita, Osaka, Japan, 565-0871 | |
| Shimane University Hospital | Recruiting |
| Izumo, Shimane, Japan, 693-8501 | |
| Fujieda Municipal General Hospital | Recruiting |
| Fujieda, Shizuoka, Japan, 426-8677 | |
| JA Shizuoka Kohseiren Enshu Hospital | Recruiting |
| Hamamatsu, Shizuoka, Japan, 430-0929 | |
| Japanese Red Cross Hamamatsu Hospital | Recruiting |
| Hamamatsu, Shizuoka, Japan, 434-8533 | |
| Sonodakai Joint Replacement Center Hospital | Recruiting |
| Adachi-ku, Tokyo, Japan, 121-0064 | |
| Medical Plaza Edogawa | Recruiting |
| Edogawa-ku, Tokyo, Japan, 133-0052 | |
| Sato Orthopaedic Clinic | Recruiting |
| Edogawa-ku, Tokyo, Japan, 134-0084 | |
| Fussa Hospital | Recruiting |
| Fussa, Tokyo, Japan, 197-8511 | |
| Jukoukai hospital | Recruiting |
| Koto-ku, Tokyo, Japan, 136-0073 | |
| Kitasato University Kitasato Institute Hospital | Terminated |
| Minato-ku, Tokyo, Japan, 108-8642 | |
| Tamagawa Hospital | Recruiting |
| Setagaya-ku, Tokyo, Japan, 158-0095 | |
| Kohno Clinical Medicine Research Institute Daisan Kitashinagawa Hospital | Recruiting |
| Shinagawa-ku, Tokyo, Japan, 140-0001 | |
| Ohimachi Orthopaedic Clinic | Recruiting |
| Shinagawa-ku, Tokyo, Japan, 140-0014 | |
| Japan Organization of Occupational Health and Safety Sanin Rosai Hospital | Recruiting |
| Yonago, Tottori, Japan, 683-8605 | |
| National Hospital Organization Chiba Medical Center | Recruiting |
| Chiba, Japan, 260-8606 | |
| Chihaya Hospital | Recruiting |
| Fukuoka, Japan, 813-8501 | |
| Kuroda Orthopedic Hospital | Recruiting |
| Fukuoka, Japan, 814-0165 | |
| Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital | Recruiting |
| Hiroshima, Japan, 730-8619 | |
| Hiroshima Prefectural Hospital | Recruiting |
| Hiroshima, Japan, 734-8530 | |
| Kumamoto Orthopaedic Hospital | Recruiting |
| Kumamoto, Japan, 862-0976 | |
| Nagayoshi General Hospital | Recruiting |
| Osaka, Japan, 547-0016 | |
| Iwasaki Orthopedic Surgery | Recruiting |
| Saitama, Japan, 330-0056 | |
| Saitama Municipal Hospital | Recruiting |
| Saitama, Japan, 336-8522 | |
| Korea, Republic of | |
| Department of Radiology | Terminated |
| Daegu, Korea, Republic of, 41944 | |
| Kyungpook National University Hospital | Terminated |
| Daegu, Korea, Republic of, 41944 | |
| Pharmacy of Clinical Trial Center | Terminated |
| Daegu, Korea, Republic of, 41944 | |
| Daegu Catholic University Medical Center | Recruiting |
| Daegu, Korea, Republic of, 42472 | |
| Department of Radiology (Imaging facility) | Recruiting |
| Daegu, Korea, Republic of, 42472 | |
| Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University Medical Center | Recruiting |
| Daegu, Korea, Republic of, 42472 | |
| Chungnam National University Hospital | Active, not recruiting |
| Daejeon, Korea, Republic of, 35015 | |
| Clinical Trials Center Pharmacy (Drug shipment only) | Active, not recruiting |
| Daejeon, Korea, Republic of, 35015 | |
| Department of Radiology (Imaging facility) | Active, not recruiting |
| Daejeon, Korea, Republic of, 35015 | |
| Chonnam National University Hospital | Recruiting |
| Gwangju, Korea, Republic of, 61469 | |
| Department of Radiology (Imaging Facility) | Recruiting |
| Gwangju, Korea, Republic of, 61469 | |
| Pharmacy of Clinical Trial Center (Drug shipment only) | Recruiting |
| Gwangju, Korea, Republic of, 61469 | |
| department of Radiology (Imaging facility) | Recruiting |
| Seol, Korea, Republic of, 07061 | |
| Clinical Trial Pharmacy ("Drug shipment only") | Recruiting |
| Seoul, Korea, Republic of, 02841 | |
| Department of Radiology (Imaging facility) | Recruiting |
| Seoul, Korea, Republic of, 02841 | |
| Korea University Anam Hospital | Recruiting |
| Seoul, Korea, Republic of, 02841 | |
| Clinical Trials Center Pharmacy (Drug shipment only) | Recruiting |
| Seoul, Korea, Republic of, 03080 | |
| Seoul National University Hospital | Recruiting |
| Seoul, Korea, Republic of, 03080 | |
| Clinical Trial Center Pharmacy (Drug shipment only) | Recruiting |
| Seoul, Korea, Republic of, 03722 | |
| Department of Radiology | Recruiting |
| Seoul, Korea, Republic of, 03722 | |
| Yonsei University Health System, Severance Hospital | Recruiting |
| Seoul, Korea, Republic of, 03722 | |
| Clinical Research Pharmacy | Recruiting |
| Seoul, Korea, Republic of, 05030 | |
| Department of Clinical Research Pharmacy, Konkuk University Medical Center | Recruiting |
| Seoul, Korea, Republic of, 05030 | |
| Department of Radiology | Recruiting |
| Seoul, Korea, Republic of, 05030 | |
| Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center | Recruiting |
| Seoul, Korea, Republic of, 05030 | |
| Konkuk University Medical Center | Recruiting |
| Seoul, Korea, Republic of, 05030 | |
| Department of Orthopedic Surgery, Samsung Medical Center | Recruiting |
| Seoul, Korea, Republic of, 06351 | |
| Clinical Trial Pharmacy (Drug shipment only) | Recruiting |
| Seoul, Korea, Republic of, 06591 | |
| Department of Radiology (Imaging facility) | Recruiting |
| Seoul, Korea, Republic of, 06591 | |
| The Catholic University of Korea Seoul St. Mary's Hospital | Recruiting |
| Seoul, Korea, Republic of, 06591 | |
| Clinical Research Pharmacy, SMG-SNU Boramae Medical Center (Drug Shipment Only) | Recruiting |
| Seoul, Korea, Republic of, 07061 | |
| Department of Clinical Research Pharmacy, SMG-SNU Boramae Medical Center ("Drug Shipment Only") | Recruiting |
| Seoul, Korea, Republic of, 07061 | |
| SMG-SNU Boramae Medical Center | Recruiting |
| Seoul, Korea, Republic of, 07061 | |
| Clinical Trials Center Pharmacy | Recruiting |
| Seoul, Korea, Republic of, 07985 | |
| Department of Radiology | Recruiting |
| Seoul, Korea, Republic of, 07985 | |
| Ewha Womans University Mokdong Hospital | Recruiting |
| Seoul, Korea, Republic of, 07985 | |
| Lithuania | |
| JSC Saules seimos medicinos centras | Recruiting |
| Kaunas, Lithuania, LT-49449 | |
| Klaipeda University Hospital | Terminated |
| Klaipeda, Lithuania, LT-92288 | |
| Republican Siauliai Hospital | Recruiting |
| Siauliai, Lithuania, LT-76231 | |
| Mexico | |
| Centro Hospitalario Mac, S.A. de C.V. | Recruiting |
| Guadajara, Jalisco, Mexico, 45050 | |
| Hospital Civil de Guadalajara Fray Antonio Alcalde | Not yet recruiting |
| Guadalajara, Jalisco, Mexico, 44280 | |
| Lab of Hospital Civil de Guadalajara Fray Antonio Alcalde | Not yet recruiting |
| Guadalajara, Jalisco, Mexico, 44280 | |
| Consultorio Medico del Dr. Federico Galvan Villegas | Recruiting |
| Guadalajara, Jalisco, Mexico, 45040 | |
| Centro de atencion e Investigacion cardiovascular del Potosi, S.C. | Not yet recruiting |
| San Luis Potosi, Mexico, 78200 | |
| Operadora de Hospitales Angeles, S.A de C.V. | Not yet recruiting |
| San Luis Potosi, Mexico, 78200 | |
| New Zealand | |
| Lakeland Clinical Trials | Recruiting |
| Rotorua, BOP, New Zealand, 3010 | |
| TRG Imaging | Recruiting |
| Rotorua, BOP, New Zealand, 3010 | |
| Otago Radiology | Recruiting |
| Dunedin, Otago, New Zealand, 9010 | |
| RMC Medical Research Ltd | Recruiting |
| Dunedin, Otago, New Zealand, 9012 | |
| South Pacific Clinical Trials | Recruiting |
| Auckland, New Zealand, 0610 | |
| TRG Imaging Lincoln Road | Recruiting |
| Auckland, New Zealand, 0610 | |
| Auckland Bone Denisty Ltd | Recruiting |
| Auckland, New Zealand, 0612 | |
| TRG Imaging | Recruiting |
| Auckland, New Zealand, 0620 | |
| North Shore Hospital, Waitemata District Health Board | Recruiting |
| Auckland, New Zealand, 0622 | |
| Star Unit, North Shore Hospital, Waitemata District Health Board | Recruiting |
| Auckland, New Zealand, 0622 | |
| The Radiology Group | Recruiting |
| Auckland, New Zealand, 0622 | |
| Southern Clinical Trials- Waitemata Ltd | Recruiting |
| Auckland, New Zealand, 0626 | |
| Optimal Clinical Trials | Recruiting |
| Auckland, New Zealand, 1010 | |
| Auckland Radiology Parnell Branch | Recruiting |
| Auckland, New Zealand, 1052 | |
| After Hours Radiology | Recruiting |
| Christchurch, New Zealand, 8013 | |
| Southern Cross Radiology | Recruiting |
| Christchurch, New Zealand, 8013 | |
| St George Radiology | Recruiting |
| Christchurch, New Zealand, 8014 | |
| Cashmere Radiology | Recruiting |
| Christchurch, New Zealand, 8022 | |
| Southern Clinical Trials Ltd | Recruiting |
| Christchurch, New Zealand, 8024 | |
| Pacific Radiology Wigram | Recruiting |
| Christchurch, New Zealand, 8042 | |
| Collingwood Street Pharmacy | Recruiting |
| Nelson, New Zealand, 7010 | |
| Nelson Radiology | Recruiting |
| Nelson, New Zealand, 7010 | |
| Porter Rheumatology Ltd | Recruiting |
| Nelson, New Zealand, 7010 | |
| Bay Radiology | Recruiting |
| Tauranga, New Zealand, 3110 | |
| P3 Research Ltd | Recruiting |
| Tauranga, New Zealand, 3110 | |
| Bay Radiology | Recruiting |
| Tauranga, New Zealand, 3112 | |
| Clinical Horizons NZ Ltd | Recruiting |
| Tauranga, New Zealand, 3112 | |
| P3 Research Ltd | Recruiting |
| Wellington, New Zealand, 6021 | |
| Pacific Radiology | Recruiting |
| Wellington, New Zealand, 6021 | |
| Peru | |
| Unidad de Investigacion en Medicina Interna y Enfermedades criticas-Hogar Clinica San Juan de Dios | Recruiting |
| Cayma, Arequipa, Peru | |
| Centro De Investigacion Clinica Trujillo EIRL/Clinica Peruano Americana S.A. | Recruiting |
| Trujillo, La Libertad, Peru, 13001 | |
| ABK REUMA S.R.L. de Medicentro Biociencias/BIO CIENCIAS PERU S.R.L. | Recruiting |
| Lima, Peru, 21 | |
| Centro de Investigación Reumatología CAA-Clinica Anglo Americana | Recruiting |
| Lima, Peru, 27 | |
| Investigaciones en Reumatologia / Centro Medico Corpac S.A. | Recruiting |
| Lima, Peru, 27 | |
| Centro de Investigaciones Medicas-Hospital Maria Auxiliadora | Recruiting |
| Lima, Peru, 29 | |
| Investigaciones Clinicas S.A.C. / Instituto de Ginecologia y Reproduccion S.A. | Recruiting |
| Lima, Peru, 33 | |
| Investigaciones Clinicas S.A.C./Instituto de Ginecologia y Reproduccion S.A. | Recruiting |
| Lima, Peru, 33 | |
| Philippines | |
| Philippine General Hospital | Active, not recruiting |
| Manila, NCR, Philippines, 1000 | |
| Manila Doctors Hospital | Recruiting |
| Manila, Philippines, 1000 | |
| Russian Federation | |
| Moscow Municipal Rheumatology Center | Recruiting |
| Moscow, Russian Federation, 119049 | |
| SBHI "City Clinical Hospital No. 1 n.a N.I. Pirogov" | Recruiting |
| Moscow, Russian Federation, 119049 | |
| SBHI "City Clinical Hospital No. 1 n.a. N.I. Pirogov" | Recruiting |
| Moscow, Russian Federation, 119049 | |
| City Neurology Center "Sibneuromed" LLC | Recruiting |
| Novosibirsk, Russian Federation, 630091 | |
| Federal State Budgetary Scientific Institution | Recruiting |
| Novosibirsk, Russian Federation, 630117 | |
| State Budgetary Institution of Ryazan Region | Recruiting |
| Ryazan, Russian Federation, 390026 | |
| Medinet LLC | Recruiting |
| Saint Petersburg, Russian Federation, 190103 | |
| Limited Liability Company "Medical Center "Reavita Med SPb" | Not yet recruiting |
| Saint Petersburg, Russian Federation, 194354 | |
| FSBI 'SRITO n.a. R.R. Vreden' MoH RF | Recruiting |
| Saint Petersburg, Russian Federation, 195427 | |
| BioEq LLC | Recruiting |
| Saint Petersburg, Russian Federation, 197342 | |
| Serbia | |
| Clinical Center of Vojvodina, Clinic for Medical Rehabilitation | Not yet recruiting |
| Novi Sad, Vojvodina, Serbia, 21000 | |
| Institute for Rehabilitation | Recruiting |
| Belgrade, Serbia, 11000 | |
| Institute of Rheumatology | Recruiting |
| Belgrade, Serbia, 11000 | |
| Institute for treatment and rehabilitation "Niska Banja" | Recruiting |
| Niska Banja, Serbia, 18205 | |
| Special Hospital for Rheumatic Diseases Novi Sad | Recruiting |
| Novi Sad, Serbia, 21000 | |
| General hospital "Dr Laza K. Lazarevic" Sabac | Recruiting |
| Sabac, Serbia, 15000 | |
| Slovakia | |
| Reumatologia s.r.o. | Recruiting |
| Bratislava, Slovakia, 820 07 | |
| Nestatna Reumatologicka Ambulancia, Poliklinika Karlova Ves | Recruiting |
| Bratislava, Slovakia, 841 04 | |
| MUDr. STRANAI s.r.o. | Recruiting |
| Kosice, Slovakia, 040 11 | |
| Reum.hapi s.r.o. | Recruiting |
| Nove Mesto nad Vahom, Slovakia, 91501 | |
| MEDIPA s.r.o. | Recruiting |
| Piestany, Slovakia, 921 01 | |
| Thermium s.r.o. | Terminated |
| Piestany, Slovakia, 92101 | |
| Taiwan | |
| Changhua Christian Hospital Clinical Trial Pharmacy | Recruiting |
| Changhua, Taiwan, 500 | |
| Changhua Christian Hospital | Recruiting |
| Changhua, Taiwan, 500 | |
| Clinical Trial Pharmacy of Department of Pharmacy | Not yet recruiting |
| Kaohsiung, Taiwan, 80756 | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Not yet recruiting |
| Kaohsiung, Taiwan, 80756 | |
| Chang Gung Memorial Hospital-Kaohsiung Branch Clinical Trial Pharmacy | Recruiting |
| Kaohsiung, Taiwan, 83301 | |
| Chang Gung Memorial Hospital-Kaohsiung Branch | Recruiting |
| Kaohsiung, Taiwan, 83301 | |
| Chung Shan Medical University Hospital Clinical Trial Pharamacy | Recruiting |
| Taichung, Taiwan, 402 | |
| Chung Shan Medical University Hospital | Recruiting |
| Taichung, Taiwan, 402 | |
| China Medical University Hospital | Recruiting |
| Taichung, Taiwan, 40447 | |
| Department of Pharmacy, China Medical University Hospita ( Drug Shipment) | Recruiting |
| Taichung, Taiwan, 40447 | |
| Ukraine | |
| Regional Communal Institution Chernivtsi Regional Clinical Hospital | Recruiting |
| Chernivtsi, Ukraine, 58001 | |
| Communal Healthcare Institution Kharkiv City Clinical Hospital No.27, Therapeutics department | Recruiting |
| Kharkiv, Ukraine, 61002 | |
| Government Institution "L.T. Malaya Therapy National Institute of the NAMS of Ukraine" | Recruiting |
| Kharkiv, Ukraine, 61039 | |
| Oleksandrivska Clinical Hospital Of Kyiv | Recruiting |
| Kyiv, Ukraine, 01601 | |
| Kyiv City Clinical Hospital 3,Rheumatology Department | Recruiting |
| Kyiv, Ukraine, 02125 | |
| Clinic of NI "NSC"M.D.Strazhesko Institute of Cardiology" of NAMS of Ukraine, | Recruiting |
| Kyiv, Ukraine, 03151 | |
| Polyclinic of Administration of Medical Services and Rehabilitation of State Stock Holding Company | Recruiting |
| Kyiv, Ukraine, 04050 | |
| Clinic of SI "Institute of Gerontology named after D.F Chebotarov of NAMS of Ukraine" | Recruiting |
| Kyiv, Ukraine, 04114 | |
| Clinic of SI Institute of Gerontology named after D.F Chebotarov of NAMS of Ukraine | Recruiting |
| Kyiv, Ukraine, 04114 | |
| Polyclinic Of Administration of Medical Services and Rehabilitation of SSHC Artem | Recruiting |
| Kyiv, Ukraine, 04119 | |
| Communal City Clinical Hospital No.5, Therapeutics Department | Recruiting |
| Lviv, Ukraine, 79013 | |
| Communal Institution "Odesa Regional Clinical Hospital" | Recruiting |
| Odesa, Ukraine, 65025 | |
| Multi-field Medical Center (University Clinic No.1) of Odesa Medical University, | Recruiting |
| Odesa, Ukraine, 65026 | |
| Communal Institution Ternopil University Hospital | Recruiting |
| Ternopil, Ukraine, 46002 | |
| Vinnytsia Regional Clinical Hospital named after M.I. Pyrogov, Rheumatology Department, | Recruiting |
| Vinnytsia, Ukraine, 21018 | |
| City Clinical Hospital 1 | Recruiting |
| Vinnytsia, Ukraine, 21029 | |
| Medical Clinical Investigational Centre of Medical Centre Health Clinic LTD | Recruiting |
| Vinnytsia, Ukraine, 21029 | |
| Scientific and Research Institute of Invalid Rehabilitation (Educational and Scientific Medical | Recruiting |
| Vinnytsia, Ukraine, 21029 | |
| Communal Institution Zaporizhzhya Regional Clinical Hospital | Recruiting |
| Zaporizhzhya, Ukraine, 69600 | |
Sponsors and Collaborators
Pfizer
Investigators
| Study Director: | Pfizer CT.gov Call Center | Pfizer |
More Information
Additional Information:
| Responsible Party: | Pfizer |
| ClinicalTrials.gov Identifier: | NCT02528188 History of Changes |
| Other Study ID Numbers: |
A4091058 2012-003721-22 ( EudraCT Number ) OA SAFETY STUDY ( Other Identifier: Alias Study Number ) |
| Study First Received: | July 19, 2015 |
| Last Updated: | July 7, 2017 |
| Studies a U.S. FDA-regulated Drug Product: | Yes | |
| Studies a U.S. FDA-regulated Device Product: | No | |
Additional relevant MeSH terms:
|
Osteoarthritis Chronic Pain Osteoarthritis, Knee Osteoarthritis, Hip Arthritis Joint Diseases Musculoskeletal Diseases Rheumatic Diseases Pain Neurologic Manifestations Nervous System Diseases Signs and Symptoms Celecoxib Diclofenac |
Naproxen Anti-Inflammatory Agents, Non-Steroidal Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Anti-Inflammatory Agents Antirheumatic Agents Gout Suppressants |
ClinicalTrials.gov processed this record on July 14, 2017