Working...
ClinicalTrials.gov
ClinicalTrials.gov Menu
Trial record 1 of 1 for:    cv185-316
Previous Study | Return to List | Next Study

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02415400
Recruitment Status : Completed
First Posted : April 14, 2015
Last Update Posted : January 11, 2019
Sponsor:
Collaborators:
Pfizer
Duke Clinical Research Institute
Information provided by (Responsible Party):
Bristol-Myers Squibb

Brief Summary:
The purpose of this study is to determine if Apixaban is safer than a Vitamin K Antagonist given for 6 months in terms of bleeding in patients with an irregular heart beat (atrial fibrillation) and a recent heart attack or a recent procedure to open up a blood vessel in the heart. All patients would also be taking a class of medicines called P2Y12 inhibitors (such as clopidogrel/Plavix) and be treated for up to 6 months. The primary focus will be a comparison of the bleeding risk of Apixaban, with or without aspirin, versus a Vitamin K antagonist, such as warfarin, with or without aspirin.

Condition or disease Intervention/treatment Phase
Acute Coronary Syndromes Drug: Apixaban Drug: vitamin K antagonist Drug: Acetylsalicylic acid Other: Acetylsalicylic acid placebo Phase 4

Detailed Description:

Patients will be recruited from either inpatient coronary care or general medical units, or recruited from outpatient cardiology offices.

Masking:

Apixaban: Open label.

VKA: Open label.

Acetylsalicylic acid film coated tablet: Double Blinded.

Placebo matching Acetylsalicylic acid film coated tablet: Double Blinded.


Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 4614 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Other
Official Title: An Open-label, 2 x 2 Factorial, Randomized Controlled, Clinical Trial to Evaluate the Safety of Apixaban vs. Vitamin K Antagonist and Aspirin vs. Aspirin Placebo in Patients With Atrial Fibrillation and Acute Coronary Syndrome or Percutaneous Coronary Intervention
Actual Study Start Date : June 4, 2015
Actual Primary Completion Date : November 10, 2018
Actual Study Completion Date : November 10, 2018

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Active Comparator: Apixaban
5 mg or 2.5 mg Apixaban tablets orally twice per day
Drug: Apixaban
Other Name: BMS-562247

Active Comparator: Vitamin K Antagonist
VKA tablets orally once daily
Drug: vitamin K antagonist
Placebo Comparator: Acetylsalicylic acid film coated tablet
81 mg Acetylsalicylic acid film coated tablet orally once daily
Drug: Acetylsalicylic acid
Other Name: Aspirin 81 mg

Placebo Comparator: Placebo matching Acetylsalicylic acid film coated tablet
Placebo matching Acetylsalicylic acid film coated tablet once daily
Other: Acetylsalicylic acid placebo
Other Name: aspirin placebo




Primary Outcome Measures :
  1. The rate of International Society on Thrombosis and Haemostasis (ISTH) major or Clinically Relevant Non-Major (CRNM) bleeding with Apixaban or VKA during the treatment period [ Time Frame: Approximately 6 months ]
    time to first ISTH major or CRNM bleeding during the time the patient is taking the medicine which is 6 months

  2. The rate of major or CRNM bleeding with aspirin and no aspirin during the treatment period between no aspirin and aspirin [ Time Frame: Approximately 6 months ]
    time to first ISTH major or CRNM bleeding during the time the patient is taking the medicine which is 6 months


Secondary Outcome Measures :
  1. Superiority on major + CRNM bleeding for Apixaban versus VKA [ Time Frame: Approximately 6 months ]
    time to first occurrence during the time the patient is taking the medicine which is 6 months

  2. The rate of the composite endpoint of death or ischemic events (stroke, myocardial infarction, stent thrombosis, urgent revascularization) with Apixaban versus VKA [ Time Frame: Approximately 6 months ]
    time to first occurrence during the time the patient is taking the medicine which is 6 months

  3. The composite endpoints of death and ischemic events (stroke, myocardial infarction, stent thrombosis, urgent revascularization) between aspirin versus placebo [ Time Frame: Approximately 6 months ]
  4. The rate of all-cause death or all-cause rehospitalization with apixaban versus VKA [ Time Frame: Approximately 6 months ]
    time to first occurrence during the time the patient is taking the medicine which is 6 months

  5. The rate of all-cause death or all-cause rehospitalization with aspirn versus no aspirin [ Time Frame: Approximately 6 months ]
    time to first occurrence during the time the patient is taking the medicine which is 6 months



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 95 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

  • Adults with either active or a history of non-valvular atrial fibrillation or flutter with the planned or existing use of an oral anticoagulant for prophylaxis of thromboembolism. In addition, subjects must have had an acute coronary syndrome or percutaneous coronary intervention with a stent within the prior 14 days
  • Planned use of antiplatelet agents for at least 1 to 6 months
  • Males and Females ≥ 18 years of age
  • Women of childbearing potential must have a negative serum or urine pregnancy test within 24 hours prior to the start of study drug

Exclusion Criteria:

  • Conditions other than atrial fibrillation that require chronic anticoagulation. (e.g. prosthetic mechanical heart valve)
  • Severe renal insufficiency (serum creatinine > 2.5 mg/dL or a calculated creatinine clearance < 30 mL/min
  • Patients with a history of intracranial hemorrhage
  • Patients have had or will undergo Coronary arterial bypass graft (CABG) for their index acute coronary syndrome (ACS) event
  • Patients with known ongoing bleeding and patients with known coagulopathies
  • Any contraindications or allergies to VKA, apixaban, or to intended P2Y12 antagonists or to aspirin

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02415400


  Hide Study Locations
Locations
Layout table for location information
United States, Alabama
Cardiovascular Associates of the Southeast, LLC
Birmingham, Alabama, United States, 35243
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294-3410
Local Institution
Huntsville, Alabama, United States, 35801
United States, Arizona
Arizona Heart Rhythm Center
Phoenix, Arizona, United States, 85013
Local Institution
Phoenix, Arizona, United States, 85054
Scottsdale Osborn Medical Center
Scottsdale, Arizona, United States, 85251
Southern Arizona VA Health Care System
Tucson, Arizona, United States, 85723
United States, Arkansas
Local Institution
Little Rock, Arkansas, United States, 72204-1858
Local Institution
Phoenix, Arkansas, United States, 85015
United States, California
Comprehensive Cardiovascular Specialists
Alhambra, California, United States, 91801
Local Institution
Culver City, California, United States, 90230
Washington Township Medical Foundation
Fremont, California, United States, 94536
California Heart Specialist, Inc.
Huntington Beach, California, United States, 92648
Foundation For Cardiovascular Medicine
La Jolla, California, United States, 92037
Local Institution
La Mesa, California, United States, 91942
Local Institution
Long Beach, California, United States, 90806
Local Institution
Long Beach, California, United States, 90822
Local Institution
Mission Viejo, California, United States, 92691
Local Institution
Rancho Mirage, California, United States, 92270
Local Institution
Reseda, California, United States, 91335
Local Institution
San Diego, California, United States, 92161
Manshadi Heart Institute
Stockton, California, United States, 95204
Local Institution
Torrance, California, United States, 90502
United States, Colorado
University of Colorado
Aurora, Colorado, United States, 80045
Local Institution
Denver, Colorado, United States, 80210
Colorado Heart and Vascular
Lakewood, Colorado, United States, 80228
United States, Connecticut
Local Institution
Norwalk, Connecticut, United States, 06851
United States, Delaware
Local Institution
Wilmington, Delaware, United States, 19803
United States, Florida
Orlando Heart Specialists
Altamonte Springs, Florida, United States, 32714
Local Institution
Bradenton, Florida, United States, 34209
Clearwater Cardiovascular and Interventional Consultants
Clearwater, Florida, United States, 33756
Local Institution
Clearwater, Florida, United States, 33756
Daytona Heart Group
Daytona Beach, Florida, United States, 32114
Local Institution
Fort Lauderdale, Florida, United States, 33316
Local Institution
Jacksonville Beach, Florida, United States, 32250
Local Institution
Jacksonville, Florida, United States, 32204
Local Institution
Jacksonville, Florida, United States, 32216
Local Institution
Jacksonville, Florida, United States, 32224
Tenet Florida Physician Services
Jupiter, Florida, United States, 33458
Local Institution
Lake Mary, Florida, United States, 32746
Local Institution
Miami, Florida, United States, 33173
Mediquest Research
Ocala, Florida, United States, 34471
Local Institution
Orlando, Florida, United States, 32825
CP Cardiology Partners
Palm Beach Gardens, Florida, United States, 33410
Bayfront Health St. Petersburg
Saint Petersburg, Florida, United States, 33701
Local Institution
Tampa, Florida, United States, 33613
Cardiology Partners
Wellington, Florida, United States, 33449
United States, Georgia
Athens Regional Cariology Group
Athens, Georgia, United States, 30606
Local Institution
Atlanta, Georgia, United States, 30342
Augusta University
Augusta, Georgia, United States, 30912
Georgia Heart Specialists
Covington, Georgia, United States, 30014
Local Institution
Cumming, Georgia, United States, 30041
Local Institution
Tucker, Georgia, United States, 30084
United States, Idaho
Saint Lukes Idaho Cardiology Associates
Boise, Idaho, United States, 83712
United States, Illinois
Medicoricium, LLC
Fairview Heights, Illinois, United States, 62208
Gateway Cardiology PC
Jerseyville, Illinois, United States, 62052
Advocate Medical Group ? Cardiology and Pulmonology
Normal, Illinois, United States, 61761
South Suburban Cardiology
Olympia Fields, Illinois, United States, 60461
United States, Indiana
Local Institution
Bloomington, Indiana, United States, 47403
Elkhart Clinic LLC
Elkhart, Indiana, United States, 46514
Roudebush VA Medical Center
Indianapolis, Indiana, United States, 46202
Reid Hospital and Health Care Services
Richmond, Indiana, United States, 47374
United States, Iowa
Midwest Cardiovascular Research Foundation
Davenport, Iowa, United States, 52803
University of Iowa Stead Family Children's Hospital
Iowa City, Iowa, United States, 52242
Northeast Iowa Family Practice Center
Waterloo, Iowa, United States, 50702
United States, Kansas
Local Institution
Kansas City, Kansas, United States, 66160
Local Institution
Wichita, Kansas, United States, 67203
Local Institution
Wichita, Kansas, United States, 67213
United States, Kentucky
Saint Elizabeth Healthcare
Crestview Hills, Kentucky, United States, 41017
University of Louisville
Louisville, Kentucky, United States, 40202
United States, Louisiana
Alexandria Cardiology Clinic
Alexandria, Louisiana, United States, 71301
Imperial Health
Lake Charles, Louisiana, United States, 70601
Local Institution
Minden, Louisiana, United States, 71055
Clinical Trials of America LA LLC - PPDS
Monroe, Louisiana, United States, 71201
United States, Massachusetts
Local Institution
Natick, Massachusetts, United States, 01760
United States, Michigan
Great Lakes Heart Center of Alpena
Alpena, Michigan, United States, 49707
Local Institution
Ann Arbor, Michigan, United States, 48109
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Local Institution
Detroit, Michigan, United States, 48202
Local Institution
Lansing, Michigan, United States, 48912
Covenant Center for the Heart
Saginaw, Michigan, United States, 48602
United States, Minnesota
Metropolitan Cardiology Consultants
Minneapolis, Minnesota, United States, 55433-4568
Local Institution
Minneapolis, Minnesota, United States, 55455
Local Institution
Rochester, Minnesota, United States, 55905-0001
United States, Mississippi
Hattiesburg Clinic
Hattiesburg, Mississippi, United States, 39401
Local Institution
Jackson, Mississippi, United States, 39216
Cardiology Associates Research LLC
Tupelo, Mississippi, United States, 38801
United States, Missouri
Missouri Cardiovascular Specialists
Columbia, Missouri, United States, 65201
Local Institution
Columbia, Missouri, United States, 65212
Freeman Health System
Joplin, Missouri, United States, 64804
Gateway Cardiology PC
Saint Louis, Missouri, United States, 63128
St. Louis Heart and Vascular
Saint Louis, Missouri, United States, 63136
Cox Health Systems
Springfield, Missouri, United States, 65807
United States, Montana
Local Institution
Billings, Montana, United States, 59101
United States, Nebraska
Bryan Heart Hospital
Lincoln, Nebraska, United States, 68506
United States, Nevada
HCP Clinical Research LLC
Las Vegas, Nevada, United States, 89169
Renown Regional Medical Center.
Reno, Nevada, United States, 89502
United States, New Jersey
New Jersey Heart
Linden, New Jersey, United States, 07036
United States, New York
Capital Cardiology Associates
Albany, New York, United States, 12211
New York-Presbyterian Brooklyn Methodist Hospital
Brooklyn, New York, United States, 11215
Local Institution
Brooklyn, New York, United States, 11217
Buffalo Heart Group LLP
Buffalo, New York, United States, 14215
Mount Sinai-St. Lukes
New York, New York, United States, 10025
Hudson Valley Cardiovascular Practice, PC
Poughkeepsie, New York, United States, 12601
United States, North Carolina
Asheville Cardiology Associates PA
Asheville, North Carolina, United States, 28801
University of North Carolina School of Medicine
Chapel Hill, North Carolina, United States, 27599
Durham VA Medical Center
Durham, North Carolina, United States, 27705
Duke University Medical Center
Durham, North Carolina, United States, 27710
Clinical Trials of America-NC, LLC - PPDS
Lenoir, North Carolina, United States, 28645
Duke Cardiology and Cardiovascular Surgery of Lumberton
Lumberton, North Carolina, United States, 28358-2981
PMG Research of Wilmington
Wilmington, North Carolina, United States, 28401
United States, Ohio
Aultman Hospital
Canton, Ohio, United States, 44710
Local Institution
Columbus, Ohio, United States, 43214
Local Institution
Kettering, Ohio, United States, 45429
Local Institution
Willoughby, Ohio, United States, 44094
United States, Pennsylvania
Saint Vincent Hospital
Erie, Pennsylvania, United States, 16544
Heart Group
Lancaster, Pennsylvania, United States, 17603
Local Institution
Natrona Heights, Pennsylvania, United States, 15065
Mercer Bucks Cardiology
Newton, Pennsylvania, United States, 18940
WellSpan York Hospital
York, Pennsylvania, United States, 17405
United States, Rhode Island
Rhode Island Hospital
Providence, Rhode Island, United States, 02903
United States, South Carolina
Columbia Heart
Columbia, South Carolina, United States, 29204
Upstate Cardiology PA
Greenville, South Carolina, United States, 29607
Roper St. Francis Healthcare
North Charleston, South Carolina, United States, 29418
Carolina Cardiology Clinical Research Institute
Rock Hill, South Carolina, United States, 29732
United States, Tennessee
Local Institution
Germantown, Tennessee, United States, 38138
Research Associates of Jackson
Jackson, Tennessee, United States, 38301
Cardiovascular Research of Knoxville
Knoxville, Tennessee, United States, 37917
Knoxville Health Managment Associates Cardiology PPM LLC
Knoxville, Tennessee, United States, 37934
Parkway Cardiology Associates PC
Oak Ridge, Tennessee, United States, 37830
United States, Texas
Local Institution
Austin, Texas, United States, 78705
Local Institution
Austin, Texas, United States, 78758
Local Institution
Dallas, Texas, United States, 75216-7167
San Antonio Military Medical Center
Fort Sam Houston, Texas, United States, 78234
Angiocardiac Care of Texas PA
Houston, Texas, United States, 77025
Local Institution
Houston, Texas, United States, 77084
Local Institution
Houston, Texas, United States, 77089
Grace Research, LLC
Huntsville, Texas, United States, 77340
Local Institution
Huntsville, Texas, United States, 77340
Local Institution
Katy, Texas, United States, 77450
Caprock Cardiac Center Research Institute
Lubbock, Texas, United States, 79410
Local Institution
McKinney, Texas, United States, 75069
Local Institution
Plano, Texas, United States, 75024
Local Institution
San Antonio, Texas, United States, 78229
Mercury Medical LLC
San Antonio, Texas, United States, 78229
Local Institution
Sealy, Texas, United States, 77474
Local Institution
Sugar Land, Texas, United States, 77479
Victoria Heart and Vascular Center
Victoria, Texas, United States, 77901
United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05403
United States, Virginia
Virginia Heart
Falls Church, Virginia, United States, 22042
Virginia Heart Group Ltd
Leesburg, Virginia, United States, 20176
CJW Medical Center
Richmond, Virginia, United States, 23235
United States, Washington
Virginia Mason Medical Center
Seattle, Washington, United States, 98101
United States, West Virginia
St Mary's Medical Center
Huntington, West Virginia, United States, 25702
United States, Wisconsin
Local Institution
Milwaukee, Wisconsin, United States, 53226
Aspirus Research Institute
Wausau, Wisconsin, United States, 54401
Argentina
Local Institution
Buenos Aires, BUA, Argentina, 1180
Local Institution
Bahia Blanca, Buenos Aires, Argentina, B8000FTD
Local Institution
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, 1406
Local Institution
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, 1431
Local Institution
Coronel Suarez, Buenos Aires, Argentina, B7540DOL
Local Institution
Lanus Oeste, Buenos Aires, Argentina, 4843
Local Institution
Mar del Plata, Buenos Aires, Argentina, 7500
Local Institution
Mar Del Plata, Buenos Aires, Argentina, B7602CBM
Local Institution
Quilmes, Buenos Aires, Argentina, 1878
Local Institution
Quilmes, Buenos Aires, Argentina, B1878GEG
Local Institution
Ramos Mejia, Buenos Aires, Argentina, B1704ESN
Local Institution
Ramos Mejia, Buenos Aires, Argentina, B1704ETD
Local Institution
San Isidro, Buenos Aires, Argentina, 1642
Local Institution
Vicente Lopez, Buenos Aires, Argentina, B1602ABQ
Local Institution
Resistencia, Chaco, Argentina, H3500CDL
Local Institution
Ciudad De Cordoba, Cordoba, Argentina, X5000JHGQ
Local Institution
Villa Allende, Cordoba, Argentina, 5105
Local Institution
Villa Maria, Cordoba, Argentina, X5901ACH
Local Institution
Rosario, Santa FE, Argentina, 2000
Local Institution
Rosario, Santa FE, Argentina, S2000DSV
Local Institution
Rosario, Santa FE, Argentina, S2000PBJ
Local Institution
Buenos Aires, Argentina, 1118
Local Institution
Buenos Aires, Argentina, 1430
Local Institution
Buenos Aires, Argentina, C1093AAS
Local Institution
Buenos Aires, Argentina, C1155ADP
Local Institution
Buenos Aires, Argentina, C1179AAB
Local Institution
Buenos Aires, Argentina, C1221ADC
Local Institution
Buenos Aires, Argentina, C1425AGC
Local Institution
Buenos Aires, Argentina, C1428CRC
Local Institution
Buenos Aires, Argentina, C1428DCO
Local Institution
Cordoba, Argentina, 5000
Local Institution
Cordoba, Argentina, 5016
Local Institution
Cordoba, Argentina, X5000AAX
Local Institution
Cordoba, Argentina, X5000EPU
Local Institution
Cordoba, Argentina, X5002AOQ
Local Institution
Cordoba, Argentina, X5004CDT
Local Institution
Cordoba, Argentina, X5006CBI
Local Institution
Cordoba, Argentina, X5008KKF
Local Institution
Cordoba, Argentina, X5016KEH
Local Institution
Corrientes, Argentina, W3400AMZ
Local Institution
Santa Fe, Argentina, 3000
Local Institution
Santa Fe, Argentina, S3000AOL
Local Institution
Santa Fe, Argentina, S3000EOZ
Local Institution
Santiago Del Estero, Argentina
Australia, New South Wales
Local Institution
Concord, New South Wales, Australia, 2139
Local Institution
Port Macquarie, New South Wales, Australia, 2444
Australia, Queensland
Local Institution
Milton, Queensland, Australia, 4064
Australia, South Australia
Local Institution
Elizabeth Vale, South Australia, Australia, 5112
Australia
Local Institution
Bedford Park, Australia, 5024
Austria
Local Institution
Graz, Austria, 8020
Local Institution
Graz, Austria, 8036
Local Institution
Graz, Austria, A-8036
Local Institution
Linz, Austria, 4010
Local Institution
Linz, Austria, 4021
Local Institution
Vienna, Austria, A-1090
Local Institution
Wien, Austria, 1100
Local Institution
Wien, Austria, 1160
Local Institution
Wien, Austria, A-1130
Belgium
Local Institution
Aalst, Belgium, 9300
Local Institution
Antwerpen, Belgium, 2020
Local Institution
Bonheiden, Belgium, 2820
Local Institution
Brasschaat, Belgium, 2930
Local Institution
Bruxelles, Belgium, 1000
Local Institution
Gent, Belgium, 9000
Local Institution
Ieper, Belgium, 8900
Local Institution
Leuven, Belgium, 3000
Local Institution
Wilrijk, Belgium, 2610
Local Institution
Yvoir, Belgium, 5530
Brazil
Local Institution
Salvador, Bahia, Brazil, 40050-410
Local Institution
Salvador, Bahia, Brazil, 41253-190
Local Institution
Salvador, Bahia, Brazil, 41810-011
Local Institution
Salvador, Bahia, Brazil, 41950-275
Local Institution
Brasilia, Distrito Federal, Brazil, 70390-700
Local Institution
Colatina, Espirito Santo, Brazil, 29702-020
Local Institution
Aparecida de Goiania, Goias, Brazil, 74915-520
Local Institution
Goiania, Goias, Brazil, 74210-050
Local Institution
Belo Horizonte, Minas Gerais, Brazil, 30110-921
Local Institution
Belo Horizonte, Minas Gerais, Brazil, 30150-320
Local Institution
Uberaba, Minas Gerais, Brazil, 38025-260
Local Institution
Uberlandia, Minas Gerais, Brazil, 38400-902
Local Institution
Campina Grande Do Sul, Parana, Brazil, 83430-000
Local Institution
Londrina, Parana, Brazil, 86010-450
Local Institution
Belem, Para, Brazil, 66087-660
Local Institution
Cabo de Santo Agostinho, Pernambuco, Brazil, 54580-812
Local Institution
Recife, Pernambuco, Brazil, 50100-060
Local Institution
Recife, Pernambuco, Brazil, 52051-380
Local Institution
Canoas, RIO Grande DO SUL, Brazil, 92425-900
Local Institution
Passo Fundo, RIO Grande DO SUL, Brazil, 99010-080
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 90020-090
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 90035-903
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 90610-000
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 90620-001
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 90840-440
Local Institution
Porto Alegre, RIO Grande DO SUL, Brazil, 91350-200
Local Institution
Blumenau, Santa Catarina, Brazil, 89010-906
Local Institution
Itajai, Santa Catarina, Brazil, 88301-303
Local Institution
Campinas, SAO Paulo, Brazil, 13060080
Local Institution
Limeira, SAO Paulo, Brazil, 13480-470
Local Institution
Marilia, SAO Paulo, Brazil, 17515-000
Local Institution
S?o Paulo, SAO Paulo, Brazil, 01327-010
Local Institution
S?o Paulo, SAO Paulo, Brazil, 04004-030
Local Institution
Santo Andre, SAO Paulo, Brazil, 09030-010
Local Institution
Sao Jose Do Rio Preto, SAO Paulo, Brazil, 15015-750
Local Institution
Votuporanga, SAO Paulo, Brazil, 15500-003
Local Institution
Rio de Janeiro, Brazil, 22271-100
Local Institution
Sao Paulo, Brazil, 01418-100
Local Institution
Sao Paulo, Brazil, 05403-000
Local Institution
Sao Paulo, Brazil, 08270
Bulgaria
Local Institution
Burgas, Bulgaria, 8000
Local Institution
Dimitrovgrad, Bulgaria, 6400
Local Institution
Haskovo, Bulgaria, 6300
Local Institution
Montana, Bulgaria, 3400
Local Institution
Pazardzhik, Bulgaria, 4400
Local Institution
Pleven, Bulgaria, 5800
Local Institution
Plovdiv, Bulgaria, 4002
Local Institution
Sandanski, Bulgaria, 2800
Local Institution
Smolyan, Bulgaria, 4700
Local Institution
Sofia, Bulgaria, 1202
Local Institution
Sofia, Bulgaria, 1407
Local Institution
Sofia, Bulgaria, 1431
Local Institution
Sofia, Bulgaria, 1505
Local Institution
Sofia, Bulgaria, 1527
Local Institution
Sofia, Bulgaria, 1606
Local Institution
Veliko Tarnova, Bulgaria, 5000
Local Institution
Vidin, Bulgaria, 3700
Canada, Alberta
Local Institution
Edmonton, Alberta, Canada, T5H 3V9
Local Institution
Edmonton, Alberta, Canada, T6G 2B7
Local Institution
Edmonton, Alberta, Canada, T6K 4C1
Canada, British Columbia
Local Institution
Kelowna, British Columbia, Canada, V1Y 1V6
Local Institution
New Westminster, British Columbia, Canada, V3L 3W4
Local Institution
Victoria, British Columbia, Canada, V8R 4R2
Canada, Manitoba
Local Institution
Winnepeg, Manitoba, Canada, R2H 2A6
Canada, Nova Scotia
Local Institution
Halifax, Nova Scotia, Canada, B3H1V7
Canada, Ontario
Local Institution
Cambridge, Ontario, Canada, N1R 7R1
Local Institution
London, Ontario, Canada, N6A 5A5
Local Institution
Oshawa, Ontario, Canada, L1J 2J9
Local Institution
Ottawa, Ontario, Canada, K1Y 4W7
Local Institution
Scarborough, Ontario, Canada, M1E 5E9
Local Institution
Scarborough, Ontario, Canada, M1P 2T7
Local Institution
Sudbury, Ontario, Canada, P3E 3B8
Local Institution
Sudbury, Ontario, Canada, P3E 5M4
Local Institution
Waterloo, Ontario, Canada, N2T 0C1
Canada, Quebec
Local Institution
Green Field Park, Quebec, Canada, J4V 2H1
Local Institution
Laval, Quebec, Canada, H7M 3L9
Local Institution
Longueuil, Quebec, Canada, J4M 2X1
Local Institution
Montreal, Quebec, Canada, H3G 1A4
Local Institution
Sherbrooke, Quebec, Canada, J1H 5N4
Local Institution
St-Georges, Beauce, Quebec, Canada, G5Y 4T8
Local Institution
St-Jean-sur-Richelieu, Quebec, Canada, J3A 1C3
Local Institution
St. Jerome, Quebec, Canada, J7Z 5T3
Canada, Saskatchewan
Local Institution
Regina, Saskatchewan, Canada, S4P 0W5
Canada
Local Institution
Montreal, Canada, H2X 3E4
Chile
Local Institution
Santiago, Metropolitana, Chile, 7500588
Local Institution
Santiago, Chile, 7930124
Colombia
Local Institution
Barranquilla, Colombia, 84-176
Local Institution
Barranquilla, Colombia
Local Institution
Bogota, Colombia
Local Institution
Cali, Colombia, 760032
Local Institution
Espinal, Colombia
Local Institution
Medellin, Colombia
Croatia
Local Institution
Cakovec, Croatia, 40000
Local Institution
Dubrovnik, Croatia, 20000
Local Institution
Karlovac, Croatia, 47000
Local Institution
Krapinske toplice, Croatia, 49217
Local Institution
Opatija, Croatia, 51410
Local Institution
Osijek, Croatia, 31000
Local Institution
Rijeka, Croatia, 51000
Local Institution
Sibenik, Croatia, 22000
Local Institution
Slavonski Brod, Croatia, 35000
Local Institution
Virovitica, Croatia, 33000
Local Institution
Zabok, Croatia, 49210
Local Institution
Zadar, Croatia, 23000
Local Institution
Zagreb, Croatia, 10000
Czechia
Local Institution
Prague 8, Czechia, 180 85
Local Institution
Praha 2, Czechia, 128 08
Local Institution
Praha 5, Czechia, 150 06
Local Institution
Tabor, Czechia, 390 03
Local Institution
Usti nad Labem, Czechia, 401 13
Local Institution
Usti Nad Orlici, Czechia, 562 18
Local Institution
Zlin, Czechia, 762 75
Denmark
Local Institution
Aabenraa, Denmark, 6200
Local Institution
Aarhus, Denmark, 8000
Local Institution
Copenhagen, Denmark, 2100
Local Institution
Copenhagen, Denmark, DK-2300
Local Institution
Frederiksburg, Denmark, 2000
Local Institution
Frederikssund, Denmark, 3600
Local Institution
Hellerup, Denmark, DK-2900
Local Institution
Hillerod, Denmark, DK-3400
Local Institution
Holb?k, Denmark, DK-4300
Local Institution
Hvidovre, Denmark, DK-2650
Local Institution
Randers, Denmark, 8900
Local Institution
Roskilde, Denmark, DK-4000
Local Institution
Slagelse, Denmark, DK-4200
France
Local Institution
Besancon, France, 25000
Local Institution
Caen, France, 14033
Local Institution
Chambray-les-Tours, France, 37170
Local Institution
Le Coudray, France, 28360
Local Institution
Lyon, France, 69365
Local Institution
Marseille, France, 13385
Local Institution
Nimes, France, 30029
Local Institution
Pau, France, 64000
Local Institution
Pessac, France, 33604
Local Institution
Toulouse, France, 31059
Germany
Local Institution
Monchengladbach, Nordrhein-Westfalen, Germany, 41061
Local Institution
Bad Friedrichshall, Germany, 74177
Local Institution
Bad Homburg, Germany, 61348
Local Institution
Bad Homburg, Germany, 63148
Local Institution
Berlin, Germany, 12351
Local Institution
Berlin, Germany, 13347
Local Institution
Berlin, Germany, 13353
Local Institution
Berlin, Germany, 13405
Local Institution
Bielefeld, Germany, 33604
Local Institution
Bonn, Germany, 53105
Local Institution
Brandenburg, Germany, 14770
Local Institution
Bremen, Germany, 28277
Local Institution
Chemnitz, Germany, 09111
Local Institution
Coburg, Germany, 96450
Local Institution
Dortmund, Germany, 44137
Local Institution
Dresden, Germany, 01067
Local Institution
Dresden, Germany, 01277
Local Institution
Erfurt, Germany, 99089
Local Institution
Erfurt, Germany, 99097
Local Institution
Erlangen, Germany, 91054
Local Institution
Essen, Germany, 45122
Local Institution
Frankfurt am Main, Germany, 65929
Local Institution
Freiburg, Germany, 79106
Local Institution
Gottingen, Germany, 37075
Local Institution
Greifswald, Germany, 17475
Local Institution
Hamburg, Germany, 20099
Local Institution
Hamburg, Germany, 22041
Local Institution
Hamburg, Germany, 22299
Local Institution
Hansestadt Stendal, Germany, 39576
Local Institution
Heidelberg, Germany, 69120
Local Institution
Hennigsdorf, Germany, 16761
Local Institution
Hoyerswerda, Germany, 02977
Local Institution
Jena, Germany, 07747
Local Institution
Jena, Germany, 7747
Local Institution
Karlsbad, Germany, 76307
Local Institution
Kassel, Germany, 34121
Local Institution
Koln, Germany, 50937
Local Institution
Lahr, Germany, 77933
Local Institution
Leipzig, Germany, 04103
Local Institution
Limburg, Germany, 65549
Local Institution
Ludenscheid, Germany, 58515
Local Institution
Luebeck, Germany, 23538
Local Institution
Magdeburg, Germany, 39120
Local Institution
Mainz, Germany, 55131
Local Institution
Mannheim, Germany, 68167
Local Institution
Neuss, Germany, 41464
Local Institution
Papenburg, Germany, 26871
Local Institution
Regensburg, Germany, 93053
Local Institution
Rostock, Germany, 18057
Local Institution
Straubing, Germany, 94315
Local Institution
Tubingen, Germany, 72076
Local Institution
Ulm, Germany, 89077
Local Institution
Ulm, Germany, 89081
Local Institution
Villingen-Schwenningen, Germany, 78052
Local Institution
Warendorf, Germany, 48231
Local Institution
Weiden i.d.OPf., Germany, 92637
Local Institution
Wismar, Germany, 23966
Local Institution
Worms, Germany, 67550
Local Institution
Wurzburg, Germany, 97080
Hungary
Local Institution
Baja, Bacs-kiskun, Hungary, 6500
Local Institution
Bekescsaba, Hungary, 5900
Local Institution
Budapest, Hungary, 1027
Local Institution
Budapest, Hungary, 1087
Local Institution
Budapest, Hungary, 1096
Local Institution
Budapest, Hungary, 1097
Local Institution
Budapest, Hungary, 1125
Local Institution
Budapest, Hungary, 1134
Local Institution
Gyor, Hungary, 9024
Local Institution
Keszthely, Hungary, 08360
Local Institution
Mosonmagyarovar, Hungary, 9200
Local Institution
Nyiregyhaza, Hungary, 4400
Local Institution
Pecs, Hungary, 7623
Local Institution
Pecs, Hungary, 7624
Local Institution
Szeged, Hungary, 6725
Local Institution
Szekszard, Hungary, 7100
Local Institution
Szolnok, Hungary, 5004
Local Institution
Szombathely, Hungary, 9700
India
Local Institution
Ahmedabad, Gujarat, India, 380060
Local Institution
Bangalore, Karnataka, India, 560034
Local Institution
Amritsar, India, 143004
Local Institution
Bangalore, India, 560069
Local Institution
Gurgaon, India, 122 001
Local Institution
Jaipur,, India, 302020
Local Institution
Lucknow, India, 226003
Local Institution
Madurai, India, 625107
Local Institution
Mangalore, India, 575002
Local Institution
Mohali, India, 160062
Local Institution
New Delhi, India, 110025
Local Institution
New Delhi, India, 110060
Local Institution
Noida, India, 201301
Local Institution
Shivamogga, India, 577205
Local Institution
Vadodara, India, 390015
Local Institution
Vijayawada, India, 520008
Israel
Local Institution
Afula, Israel, 18101
Local Institution
Ashkelon, Israel, 78278
Local Institution
Hadera, Israel, 38100
Local Institution
Haifa, Israel, 31048
Local Institution
Haifa, Israel, 31096
Local Institution
Haifa, Israel, 34361
Local Institution
Herzliya, Israel, 46851
Local Institution
Holon, Israel, 58100
Local Institution
Jerusalem, Israel, 91240
Local Institution
Ramat-Gan, Israel, 52621
Local Institution
Rehovot, Israel, 76100
Local Institution
Safed, Israel, 13100
Local Institution
Tel Aviv, Israel, 64239
Local Institution
Tiberias, Israel, 15208
Italy
Local Institution
Acquaviva delle Fonti, Italy, 70021
Local Institution
Bergamo, Italy, 24125
Local Institution
Bergamo, Italy, 24127
Local Institution
Brescia, Italy, 25123
Local Institution
Chieti, Italy, 66100
Local Institution
Cona, Italy, 44124
Local Institution
Cremona, Italy, 26100
Local Institution
Grosseto, Italy, 58100
Local Institution
Napoli, Italy, 80131
Local Institution
Parma, Italy, 43100
Local Institution
Pavia, Italy, 27100
Local Institution
Roma, Italy, 00161
Local Institution
San Daniele Del Friuli, Italy, 33038
Korea, Republic of
Local Institution
Busan, Korea, Republic of, 602-739
Local Institution
Changwon, Korea, Republic of, 51353
Local Institution
Daegu, Korea, Republic of, 700-712
Local Institution
Daegu, Korea, Republic of, 705717
Local Institution
Daejeon, Korea, Republic of, 35015
Local Institution
Gwang Ju, Korea, Republic of, 501-757
Local Institution
Incheon, Korea, Republic of, 21431
Local Institution
Seongnam-si, Korea, Republic of, 13620
Local Institution
Seoul, Korea, Republic of, 03080
Local Institution
Seoul, Korea, Republic of, 08308
Local Institution
Seoul, Korea, Republic of, 130-710
Local Institution
Seoul, Korea, Republic of, 138736
Mexico
Local Institution
Torreon, Coahuila, Mexico, 27000
Local Institution
Leon, Guanajuato, Mexico, 37150
Local Institution
Guadalajara, Jalisco, Mexico, 44340
Local Institution
Monterrey, Nuevo LEON, Mexico, 64000
Local Institution
San Juan del Rio, Queretaro, Mexico, 76800
Local Institution
Culiacan, Sinaloa, Mexico, 80230
Local Institution
Aguascalientes, Mexico, 20230
Local Institution
Durango, Mexico, 34080
Local Institution
Puebla, Mexico, 72197
Local Institution
Queretaro, Mexico, 76000
Local Institution
San Luis Potosi, Mexico, 78200
Local Institution
San Luis Potosi, Mexico, 78240
Local Institution
Veracruz, Mexico, 91910
Netherlands
Local Institution
's-hertogenbosch, Netherlands, 5211 NL
Local Institution
Almelo, Netherlands, 7609 PP
Local Institution
Amsterdam, Netherlands, 1034 CS
Local Institution
Amsterdam, Netherlands, 1061 AE
Local Institution
Arnhem, Netherlands, 6815 AD
Local Institution
Breda, Netherlands, 4818 CK
Local Institution
Breda, Netherlands, 4819 EV
Local Institution
Den Haag, Netherlands, 2545 CH
Local Institution
Doetinchem, Netherlands, 7009 BL
Local Institution
Ede, Netherlands, 6716 RP
Local Institution
Emmen, Netherlands, 7824 AA
Local Institution
Groningen, Netherlands, 9728NT
Local Institution
Hardenberg, Netherlands, 7772 SE
Local Institution
Heerlen, Netherlands, 6401 CS
Local Institution
Leiden, Netherlands, 2334 CK
Local Institution
Leiderdorp, Netherlands, 2353 GA
Local Institution
Maastricht, Netherlands, 6211 LK
Local Institution
Nieuwegein, Netherlands, 3435 CM
Local Institution
Roosendaal, Netherlands, 4708 AE
Local Institution
Rotterdam, Netherlands, 3045 PM
Local Institution
Rotterdam, Netherlands, 3075 EA
Local Institution
Tilburg, Netherlands, 5042 AD
Local Institution
Uden, Netherlands, 5406 PT
Local Institution
Veldhoven, Netherlands, 5504 DB
Norway
Local Institution
Bod?, Norway, NO-8005
Local Institution
Oslo, Norway, 450
Local Institution
Oslo, Norway, NO-370
Local Institution
Skien, Norway, N-3710
Local Institution
Stavanger, Norway, 4068
Local Institution
Tromso, Norway, 9038
Peru
Local Institution
Miraflores, Lima, Peru, Lima 14
Local Institution
Miraflores, Lima, Peru
Local Institution
Callao, Peru, Callao 02
Local Institution
Callao, Peru, Callao 2
Local Institution
Cusco, Peru, Cusco 84
Local Institution
Lima, Peru, Lima 11
Local Institution
Lima, Peru, Lima 31
Poland
Local Institution
Bialystok, Poland, 15-276
Local Institution
Bydgoszcz, Poland, 85-168
Local Institution
Bytom, Poland, 41-902
Local Institution
Chojnice, Poland, 89-600
Local Institution
Gdynia, Poland, 81-423
Local Institution
Gdynia, Poland, 81-472
Local Institution
Katowice, Poland, 40-060
Local Institution
Kielce, Poland, 25-020
Local Institution
Krakow, Poland, 30-082
Local Institution
Krakow, Poland, 30-510
Local Institution
Krakow, Poland, 31-202
Local Institution
Krakow, Poland, 31-501
Local Institution
Lodz, Poland, 91-078
Local Institution
Lodz, Poland, 91-347
Local Institution
Lodz, Poland, 92-213
Local Institution
Lubin, Poland, 59-301
Local Institution
Opole, Poland, 45-418
Local Institution
Plock, Poland, 09-402
Local Institution
Poznan, Poland, 61-848
Local Institution
Radom, Poland, 26-617
Local Institution
Siemianowice Slaskie, Poland, 41-100
Local Institution
Szczecin, Poland, 70-506
Local Institution
Torun, Poland, 87-100
Local Institution
Warszawa, Poland, 01-211
Local Institution
Warszawa, Poland, 04-073
Local Institution
Wloclawek, Poland, 87-800
Local Institution
Wroclaw, Poland, 50-315
Local Institution
Wroclaw, Poland, 50-981
Portugal
Local Institution
Almada, Portugal, 2801-951
Local Institution
Aveiro, Portugal, 3814-501
Local Institution
Braga, Portugal, 4710-243
Local Institution
Coimbra, Portugal, 3000-075
Local Institution
Covilha, Portugal, 6200-251
Local Institution
Guimar?es, Portugal, 4835-044
Local Institution
Leiria, Portugal, 2410-187
Local Institution
Lisboa, Portugal, 1649-035
Local Institution
Senhora da Hora, Portugal, 4464-513
Local Institution
Vila Real, Portugal, 5000-508
Puerto Rico
Local Institution
Caguas, Puerto Rico, 00725
Romania
Local Institution
Baia Mare, Romania, 430031
Local Institution
Brasov, Romania, 500326
Local Institution
Bucharest, Romania, 022328
Local Institution
Bucharest, Romania, 050098
Local Institution
Cluj Napoca, Romania, 400001
Local Institution
Cluj-Napoca, Romania, 400006
Local Institution
Cluj-Napoca, Romania, 400347
Local Institution
Craiova, Romania, 200642
Local Institution
Oradea, Romania, 410169
Local Institution
Pitesti, Romania, 110283
Local Institution
Sibiu, Romania, 550172
Local Institution
Targoviste, Romania, 130095
Local Institution
Targu Mures, Romania, 540136
Local Institution
Timisoara, Romania, 300079
Local Institution
Timisoara, Romania, 300310
Local Institution
Tirgu Mures, Romania, 540042
Local Institution
Tirgu Mures, Romania, 540136
Russian Federation
Local Institution
Ekaterinburg, Russian Federation, 620026
Local Institution
Gatchina, Russian Federation, 188300
Local Institution
Kazan, Russian Federation, 420103
Local Institution
Krasnodar, Russian Federation, 350012
Local Institution
Krasnodar, Russian Federation, 350086
Local Institution
Moscow, Russian Federation, 111539
Local Institution
Moscow, Russian Federation, 117292
Local Institution
Moscow, Russian Federation, 121309
Local Institution
Moscow, Russian Federation, 121552
Local Institution
Novosibirsk, Russian Federation, 630047
Local Institution
Novosibirsk, Russian Federation, 630055
Local Institution
Saint Petersburg, Russian Federation, 192242
Local Institution
Samara, Russian Federation, 443070
Local Institution
Saratov, Russian Federation, 410028
Local Institution
Saratov, Russian Federation, 410054
Local Institution
Sochi, Russian Federation, 354057
Local Institution
St. Petersburg, Russian Federation, 195067
Local Institution
St. Petersburg, Russian Federation, 195257
Local Institution
St. Petersburg, Russian Federation, 196601
Local Institution
St. Petersburg, Russian Federation, 198013
Local Institution
St. Petersburg, Russian Federation, 199106
Local Institution
Tyumen, Russian Federation, 625000
Local Institution
Tyumen, Russian Federation, 625026
Serbia
Local Institution
Belgarde, Serbia, 11000
Local Institution
Belgrade, Serbia, 11000
Local Institution
Belgrade, Serbia, 11080
Local Institution
Nis, Serbia, 18000
Local Institution
Sremska Kamenica, Serbia, 21204
Local Institution
Uzice, Serbia, 31000
Slovakia
Local Institution
Banska Bystrica, Slovakia, 974 01
Local Institution
Bardejov, Slovakia, 085 01
Local Institution
Bratislava, Slovakia, 813 69
Local Institution
Bratislava, Slovakia, 833 48
Local Institution
Brezno, Slovakia, 977 42
Local Institution
Kosice, Slovakia, 040 01
Local Institution
Kosice, Slovakia, 040 22
Local Institution
Kosice, Slovakia, 04001
Local Institution
Nitra, Slovakia, 950 01
Local Institution
Spisska Nova Ves, Slovakia, 052 01
Local Institution
Trebisov, Slovakia, 075 01
Local Institution
Trencin, Slovakia, 911 01
Spain
Local Institution
Majadahonda, Madrid, Spain, 28222
Local Institution
Alicante, Spain, ?03010
Local Institution
Barcelona, Spain, 08036
Local Institution
Cordoba, Spain, 14004
Local Institution
Huelva, Spain, 21005
Local Institution
Madrid, Spain, 28007
Local Institution
Madrid, Spain, 28031
Local Institution
Madrid, Spain, 28034
Local Institution
Madrid, Spain, 28040
Local Institution
Malaga, Spain, 29010
Local Institution
Marbella, Spain, 29603
Local Institution
Palma de Mallorca, Spain, 07198
Local Institution
San Sebastian, Spain, 20080
Local Institution
Valencia, Spain, 46010
Local Institution
Valencia, Spain, 46014
Sweden
Local Institution
Eskilstuna, Sweden, 63188
Local Institution
Goteborg, Sweden, 413 45
Local Institution
Jonkoping, Sweden, 551 85
Local Institution
Ostersund, Sweden, SE-83183
Local Institution
Skelleftea, Sweden, 931 81
Local Institution
Stockholm, Sweden, 112 81
Local Institution
Uppsala, Sweden, 755 92
Switzerland
Local Institution
Bern, Switzerland, 3010
Local Institution
Geneve, Switzerland, CH-1205
Local Institution
Winterthur, Switzerland, 8401
Ukraine
Local Institution
Cherkasy, Ukraine, 18009
Local Institution
Chernivtsi, Ukraine, 58013
Local Institution
Dnipropetrovsk, Ukraine, 49006
Local Institution
Ivano-Frankivsk, Ukraine, 76018
Local Institution
Kharkiv, Ukraine, 61058
Local Institution
Kharkiv, Ukraine, 61103
Local Institution
Kharkiv, Ukraine, 61176
Local Institution
Kyiv, Ukraine, 01601
Local Institution
Kyiv, Ukraine, 02091
Local Institution
Kyiv, Ukraine, 03049
Local Institution
Kyiv, Ukraine, 03115
Local Institution
Kyiv, Ukraine, 03680
Local Institution
Lutsk, Ukraine, 43005
Local Institution
Lutsk, Ukraine, 43024
Local Institution
Mykolaiv, Ukraine, 54003
Local Institution
Mykolayiv, Ukraine, 54003
Local Institution
Odesa, Ukraine, 65014
Local Institution
Uzhhorod, Ukraine, 88014
Local Institution
Vinnytsia, Ukraine, 21005
Local Institution
Vinnytsia, Ukraine, 21029
Local Institution
Zhaporizhzhya, Ukraine, 69000
United Kingdom
Local Institution
Bournemouth, Dorset, United Kingdom, BH7 7DW
Local Institution
Kirkcaldy, Fife, United Kingdom, KY2 5AH
Local Institution
Stevenage, Hertfordshire, United Kingdom, SG1 4AB
Local Institution
Liverpool, Merseyside, United Kingdom, L14 3PE
Local Institution
Northampton, Northamptonshire, United Kingdom, NN1 5BD
Local Institution
Doncaster, South Yorkshire, United Kingdom, DN2 5LT
Local Institution
Sheffield, South Yorkshire, United Kingdom, S5 7AU
Local Institution
Newcastle Upon Tyne, Tyne and Wear, United Kingdom, NE7 7DN
Local Institution
Birmingham, WEST Midlands, United Kingdom, B18 7QH
Local Institution
Dudley, WEST Midlands, United Kingdom, DY1 2HQ
Local Institution
Dundee, United Kingdom, DD1 9SY
Local Institution
Wolverhampton, United Kingdom, WV10 0QP
Virgin Islands (U.S.)
Local Institution
Christiansted, Virgin Islands (U.S.), 00820
Sponsors and Collaborators
Bristol-Myers Squibb
Pfizer
Duke Clinical Research Institute
Investigators
Layout table for investigator information
Study Director: Bristol-Myers Squibb Bristol-Myers Squibb

Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Layout table for additonal information
Responsible Party: Bristol-Myers Squibb
ClinicalTrials.gov Identifier: NCT02415400     History of Changes
Other Study ID Numbers: CV185-316
2014-002004-24 ( EudraCT Number )
First Posted: April 14, 2015    Key Record Dates
Last Update Posted: January 11, 2019
Last Verified: January 2019

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
Layout table for MeSH terms
Syndrome
Atrial Fibrillation
Acute Coronary Syndrome
Disease
Pathologic Processes
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Myocardial Ischemia
Vascular Diseases
Vitamins
Vitamin K
Aspirin
Apixaban
Micronutrients
Nutrients
Growth Substances
Physiological Effects of Drugs
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Anti-Inflammatory Agents
Antirheumatic Agents
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
Platelet Aggregation Inhibitors
Cyclooxygenase Inhibitors