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Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

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ClinicalTrials.gov Identifier: NCT02239120
Recruitment Status : Recruiting
First Posted : September 12, 2014
Last Update Posted : January 10, 2018
Information provided by (Responsible Party):

Study Description
Brief Summary:
This trial will enroll approximately 6,000 patients with recent embolic stroke of unknown source (ESUS). Patients will be randomized to dabigatran or acetylsalicyclic acid (ASA) (1:1 ratio) and have visits every three months. The study doctor may prescribe blinded concomitant ASA for pts with coronary artery disease but this is not mandatory. All Adverse Events (AEs), Serious Adverse Events (SAEs), outcome events will be recorded. The trial will conclude when the required number of stroke events are positively adjudicated which is estimated to take 3 years (including 2.5 years of enrollment).

Condition or disease Intervention/treatment Phase
Stroke Secondary Prevention Drug: optional ASA as comedication Drug: placebo to ASA Drug: placebo to optional ASA as comedication Drug: placebo to dabigatran etexilate Drug: ASA 100 mg Drug: dabigatran etexilate Phase 3

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 6000 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Prevention
Official Title: Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embolic Stroke of Undetermined Source (RESPECT ESUS)
Actual Study Start Date : November 27, 2014
Estimated Primary Completion Date : July 31, 2018
Estimated Study Completion Date : July 31, 2018

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: dabigatran etexilate 110 or 150 mg
Patients will be assigned Dabigatran 150 mg b.i.d. (unless they are 75 years or older, or have a Creatinine Clearance (CrCl) of greater than or equal to 30 to less than 50ml/min (or experience GI bleed during trial), in which case they will receive Dabigatran 110 mg b.i.d.). All patients in this arm will also receive ASA placebo (q.d.)
Drug: optional ASA as comedication
optional concomitant treatment which can be used for patients with coronary artery disease. It is not required for these pts.
Drug: placebo to ASA
placebo to comparator drug
Drug: dabigatran etexilate
active drug
Active Comparator: ASA 100 mg
All patients will receive blinded ASA 100 mg q.d. and dabigatran placebo 150 mg b.i.d. (unless they are 75 years or older, or have a CrCl of greater than or equal to 30 to less than 50ml/min (or experience GI bleed during trial), in which case they will receive placebo Dabigatran 110 mg b.i.d
Drug: placebo to optional ASA as comedication
optional concomitant treatment which can be used for patients with coronary artery disease. It is not required for these pts.
Drug: placebo to dabigatran etexilate
Drug: ASA 100 mg
active comparator drug

Outcome Measures

Primary Outcome Measures :
  1. Time to first recurrent stroke (ischemic, hemorrhagic, or unspecified) [ Time Frame: up to 36 months ]

Secondary Outcome Measures :
  1. Time to Ischemic Stroke [ Time Frame: up to 36 months ]
  2. Composite endpoint of (time to) nonfatal stroke, nonfatal myocardial infarction (MI) and cardiovascular death [ Time Frame: up to 36 months ]
  3. Time to Disabling stroke (modified Rankin Scale greater than or equal to 4, as determined 3 months after recurrent stroke) [ Time Frame: up to 36 months ]
  4. Time to All-cause death [ Time Frame: up to 36 months ]
  5. Time to first major bleed [ Time Frame: up to 36 months ]
  6. Time to first intracranial hemorrhage [ Time Frame: up to 36 months ]
  7. Time to life-threatening bleed [ Time Frame: up to 36 months ]
  8. Fatal bleed [ Time Frame: up to 36 months ]
  9. Time to any bleed (all severities) [ Time Frame: up to 36 months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 150 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria:

  • Ischemic stroke with a brain lesion visualized by neuroimaging (either brain Computed Tomography (CT) or Magnetic Resonance Image (MRI)). The visualized stroke is a non-lacunar infarct , e.g. involving the cortex or >1.5 cm (>2.0 cm if measured on MRI diffusion-weighted images) in largest diameter if exclusively subcortical.Visualization by CT usually requires delayed imaging >24-48 hours after stroke onset.
  • The index stroke must have occurred either up to 3 months before randomization (Modified Rankin Scale(mRS) <=3 at randomization) or up to 6 months before randomization (mRS <=3 at randomization) in selected patients that are >= 60 years plus at least one additional risk factor for recurrent stroke.
  • Arterial imaging or cervical plus TCD ultrasonography does not show extra-cranial or intracranial atherosclerosis with >= 50% luminal stenosis in artery supplying the area of acute ischemia.
  • As evidenced by cardiac monitoring for >= 20 hours with automated rhythm detection, there is absence of AF > 6 minutes in duration (within a 20 hour period, either as single episode or cumulative time of multiple episodes).

Further inclusion criteria apply.

Exclusion criteria:

  • Modified Rankin Scale of >=4 at time of randomization or inability to swallow medications.
  • Major risk cardioembolic source of embolism such as: a) intracardiac thrombus as evidenced by transthoracic or transesophageal echocardiography, b) paroxysmal, persistent or permanent AF, c) atrial flutter, d) prosthetic cardiac valve (mitral or aortic, bioprosthetic or mechanical), e) atrial myxoma, f) other cardiac tumors, g) moderate or severe mitral stenosis, h) recent (< 4weeks) myocardial infarction, i) valvular vegetations, or j) infective endocarditis.
  • Any indication that requires treatment with an anticoagulant as per Investigator`s judgment.
  • History of atrial fibrillation (unless it was due to reversible causes such as hyperthyroidism or binge drinking, and has been permanently resolved).
  • Other specific stroke etiology (i.e. cerebral arteritis or arterial dissection, migraine with aura/vasospasm, drug abuse).
  • Renal impairment with estimated creatinine clearance (as calculated by Cockcroft-Gault equation) <30mL/min at screening, or where Investigator expects creatinine clearance is likely to drop below 30mL/min during the course of the study.

Further exclusion criteria apply.

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02239120

Contact: Boehringer Ingelheim Call Center 1-800-243-0127 clintriage.rdg@boehringer-ingelheim.com

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United States, Arizona
Bronislava Shafran, MD PC Recruiting
Phoenix, Arizona, United States, 85006
United States, Arkansas
University of Arkansas for Medical Sciences Recruiting
Little Rock, Arkansas, United States, 72205
United States, California
Westside Medical Associates of Los Angeles Recruiting
Beverly Hills, California, United States, 90211
TriWest Research Associates, LLC Recruiting
El Cajon, California, United States, 92020
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Fresno, California, United States, 93721
Glendale Adventist Medical Center Recruiting
Glendale, California, United States, 91206
Collaborative Neuroscience Network, LLC (CNS) Recruiting
Long Beach, California, United States, 90806
Kaiser Permanente Los Angeles Medical Center Recruiting
Los Angeles, California, United States, 90027
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Los Angeles, California, United States, 90095
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Pasadena, California, United States, 91105
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San Diego, California, United States, 92103
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San Francisco, California, United States, 94143
Harmeet Sachdev, MD Recruiting
San Jose, California, United States, 95124
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University of Colorado Denver Recruiting
Aurora, Colorado, United States, 80045
Colorado Neurological Institute Recruiting
Englewood, Colorado, United States, 80113
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Fort Collins, Colorado, United States, 80528
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Grand Junction, Colorado, United States, 81501
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Hartford, Connecticut, United States, 06102
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Washington, District of Columbia, United States, 20037
United States, Florida
JEM Research Institute Recruiting
Atlantis, Florida, United States, 33462
Boca Raton Regional Hospital Recruiting
Boca Raton, Florida, United States, 33486
Tenet Florida Physician Services Recruiting
Boynton Beach, Florida, United States, 33472
Nova Clinical Research, LLC Terminated
Bradenton, Florida, United States, 34209
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Deerfield Beach, Florida, United States, 33064
Center for Advanced Research Excellence Recruiting
Hialeah, Florida, United States, 33016
Bruce W. Carter, Miami VA Healthcare System Recruiting
Miami, Florida, United States, 33125
University of Miami Recruiting
Miami, Florida, United States, 33136
Bay Neurological Institute Recruiting
Panama City, Florida, United States, 32405
Carol L Pappas, MD PhD PA Recruiting
Saint Petersburg, Florida, United States, 33713
University of South Florida Recruiting
Tampa, Florida, United States, 33606
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Vero Beach, Florida, United States, 32960
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West Palm Beach, Florida, United States, 33409
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Augusta, Georgia, United States, 30912
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Marietta, Georgia, United States, 30060
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Honolulu, Hawaii, United States, 96813
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Saint Alphonsus Medical Center-Neurology Recruiting
Boise, Idaho, United States, 83704
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Northwest Heart Clinical Research, LLC Recruiting
Arlington Heights, Illinois, United States, 60005
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Chicago, Illinois, United States, 60611
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Chicago, Illinois, United States, 60612
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Chicago, Illinois, United States, 60637
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Fairview Heights, Illinois, United States, 62208
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Peoria, Illinois, United States, 61637
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Quincy, Illinois, United States, 62301
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Springfield, Illinois, United States, 62702
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Anderson, Indiana, United States, 46011
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Fort Wayne, Indiana, United States, 46845
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Des Moines, Iowa, United States, 50314
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Louisville, Kentucky, United States, 40202
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Marrero, Louisiana, United States, 70072
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Baltimore, Maryland, United States, 21287
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Bay City, Michigan, United States, 48708
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Detroit, Michigan, United States, 48202
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Flint, Michigan, United States, 48532
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Grand Rapids, Michigan, United States, 49503
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Lansing, Michigan, United States, 48912
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Pontiac, Michigan, United States, 48341
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The Duluth Clinic dba Essentia Health Duluth Clinic Recruiting
Duluth, Minnesota, United States, 55805
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Minneapolis, Minnesota, United States, 55407
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Jackson, Mississippi, United States, 39216
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Saint Louis, Missouri, United States, 63104
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Springfield, Missouri, United States, 65804
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The Nebraska Medical Center Recruiting
Omaha, Nebraska, United States, 68198
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Renown Institute for Neurosciences Recruiting
Reno, Nevada, United States, 89502
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Brooklyn, New York, United States, 11235
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Cortlandt Manor, New York, United States, 10567
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Johnson City, New York, United States, 13790
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Manhasset, New York, United States, 11030
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Mineola, New York, United States, 11501
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New York, New York, United States, 10003
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Rochester, New York, United States, 14621
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Novant Health Neurology Specialists Recruiting
Charlotte, North Carolina, United States, 28207
Duke Clinic 1L Recruiting
Durham, North Carolina, United States, 27710
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Greensboro, North Carolina, United States, 27401
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Hickory, North Carolina, United States, 28602
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Altru Health System Terminated
Grand Forks, North Dakota, United States, 58201
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The Ohio State University Wexner Medical Center Recruiting
Columbus, Ohio, United States, 43210
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Gallipolis, Ohio, United States, 45631
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Willow Grove, Pennsylvania, United States, 19090
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Providence, Rhode Island, United States, 02903
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Greenville, South Carolina, United States, 29605
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Knoxville, Tennessee, United States, 37920
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Memphis, Tennessee, United States, 38105
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Nashville, Tennessee, United States, 37203
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Nashville, Tennessee, United States, 37205
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Austin, Texas, United States, 78705
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Houston, Texas, United States, 77030
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Houston, Texas, United States, 77030
Bhupesh Dihenia, M.D.,P.A. Recruiting
Lubbock, Texas, United States, 79410
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University of Vermont Terminated
Burlington, Vermont, United States, 05401
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Virginia Commonwealth University Recruiting
Richmond, Virginia, United States, 23298
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Roanoke, Virginia, United States, 24016
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Seattle, Washington, United States, 98101
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Seattle, Washington, United States, 98122
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Huntington, West Virginia, United States, 25701
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Caba, Argentina, C1093AAS
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Caba, Argentina, C1199ABD
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Cordoba, Argentina, X5003DCE
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Coronel Suarez, Argentina, B7540DOL
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Mar del Plata, Argentina, B7600CBM
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Camperdown, New South Wales, Australia, 2050
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Darlinghurst, New South Wales, Australia, 2010
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Kanwal, New South Wales, Australia, 2259
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New Lambton, New South Wales, Australia, 2305
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St Leonards, New South Wales, Australia, 2038
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Herston, Queensland, Australia, 4029
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Nambour, Queensland, Australia, 4560
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Adelaide, South Australia, Australia, 5000
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Adelaide, South Australia, Australia, 5001
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Box Hill, Victoria, Australia, 3128
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Heidelberg, Victoria, Australia, 3084
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Parkville, Victoria, Australia, 3050
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Victoria, Australia, 3004
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Graz, Austria, 8036
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Innsbruck, Austria, 6020
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Linz, Austria, 4020
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Linz, Austria, 4021
KH d. Barmherzigen Brüder Linz, Neurologie Recruiting
Linz, Austria, 4021
Universitätsklinikum Tulln, Abteilung für Neurologie Recruiting
Tulln, Austria, 3430
Hosp.Hietzing with Neuro.Centr Rosenhuegel,II Neuro.dep,Wien Recruiting
Vienna, Austria, 1130
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Wien, Austria, 1160
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Aalst, Belgium, 9300
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Arlon, Belgium, 6700
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Brugge, Belgium, 3000
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Brussel, Belgium, 1020
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Brussel, Belgium, 1180
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Bruxelles, Belgium, 1200
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Gent, Belgium, 9000
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Kortrijk, Belgium, 8500
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Leuven, Belgium, 3000
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Liège, Belgium, 4000
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Roeselare, Belgium, 8800
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Rumst, Belgium, 2840
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Sint-Truiden, Belgium, 3800
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Wilrijk, Belgium, 2610
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Yvoir, Belgium, 5530
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Botucatu, Brazil, 18618-000
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Curitiba, Brazil, 80050-250
Clinica Neurologica e Neurocirurgica de Joinvile Recruiting
Joinvile, Brazil, 89202-165
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Porto Alegre, Brazil, 90035-903
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Ribeirao Preto, Brazil, 14048-900
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Rio de Janeiro, Brazil
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Calgary, Alberta, Canada, T2N 2T9
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Edmonton, Alberta, Canada, T6G 2B7
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Edmonton, Alberta, Canada, T6L 5X8
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St. John's, Newfoundland and Labrador, Canada, A1B 3V6
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London, Ontario, Canada, N6A 5A5
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Toronto, Ontario, Canada, M5T 2S8
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Montreal, Quebec, Canada, H3G 1A4
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Sherbrooke, Quebec, Canada, J1H 5N4
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St-Jerome, Quebec, Canada, J7Z 5T3
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Santiago, Chile, 7650568
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Santiago, Chile
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Temuco, Chile
Beijing Tiantan Hospital affiliated to Cap Med University Recruiting
Beijing, China, 100050
Peking University Third Hospital Recruiting
Beijing, China, 100191
Beijing Hospital Recruiting
Beijing, China, 100730
First Hospital of Jilin University Recruiting
Changchun, China, 130021
Xiangya Hospital, Central South University Recruiting
Changsha, China, 410008
First Affiliated Hospital of Guangzhou Medical University Recruiting
Guangzhou, China, 510000
First Affiliated Hospital of Guangzhou University of TCM Recruiting
Guangzhou, China, 510000
The First Affiliated Hospital of Jinan University Recruiting
Guangzhou, China, 510630
The Affiliated Hospital of Guizhou Medical University Recruiting
Guiyang, China, 550000
2nd Affiliated Hosp Zhejiang University College of Medical Recruiting
Hangzhou, China, 310009
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Hangzhou, China, 310013
Hangzhou Second People's Hospital Recruiting
Hangzhou, China, 310015
Sir Run Run Shaw Hospital Active, not recruiting
Hangzhou, China, 310016
Jinlin Central Hospital Recruiting
Jilin, China, 132602
The Second Affiliated Hospital to Nanchang University Recruiting
Nanchang, China, 330006
Nanjing Drum Tower Hospital Recruiting
Nanjing, China, 210008
Zhongda Hospital Southeast University Recruiting
Nanjing, China, 210009
QingDao Municipal Hospital Recruiting
Qingdao, China, 266071
The affiliated hospital of medicalcollege qingdao university Recruiting
Qingdao, China, 266555
Shanghai Changzheng Hospital Recruiting
Shanghai, China, 200003
Huashan Hospital, Fudan University Recruiting
Shanghai, China, 200040
Tongji Hospital, Tongji University Recruiting
Shanghai, China, 200065
Shanghai First People's Hospital Recruiting
Shanghai, China, 200080
General Hospital of Shenyang Military Region Recruiting
Shenyang, China, 110016
First Affiliated Hospital of Xiamen University Recruiting
Xiamen, China, 361003
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Xuzhou, China, 221002
Servicios Médicos Muñoz Solano Recruiting
Bogotá, Colombia
Sociedad de Cirugia de Bogota Hospital de San José Recruiting
Bogotá, Colombia
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Cali, Colombia
Fundación Cardiovascular de Colombia Recruiting
Floridablanca, Colombia
General Hospital Varazdin Recruiting
Varazdin, Croatia, 42000
Clin.Hosp.Centre Zagreb,Cerebrovascul.disease w/ intens.care Recruiting
Zagreb, Croatia, 10 000
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Zagreb, Croatia, 10 000
Univ. Hosp. Sisters of Mercy, Neurology Clinic, Zagreb Recruiting
Zagreb, Croatia, 100 00
Cerebrovascular site, private prac., Brno Recruiting
Brno, Czechia, 60200
Hospital Jihlava Recruiting
Jihlava, Czechia, 58633
University Hospital Olomouc Recruiting
Olomouc, Czechia, 77900
Cerebrovascular site, Ostrava Recruiting
Ostrava, Czechia, 70300
Cerebrovascular site, Ostrava Recruiting
Ostrava, Czechia, 70800
Hospital Homolka, Prague Recruiting
Prague 5, Czechia, 15006
University Hospital Motol Recruiting
Praha 5, Czechia, 150 06
East Estonia Central Hospital, Neurology Dept, Ahtme Recruiting
Ahtme, Estonia, 31025
West Tallinn Central Hospital, Neurology Dept. Recruiting
Tallinn, Estonia, 10617
North Estonia Medical Centre Foundation, Tallin Active, not recruiting
Tallinn, Estonia, 13419
Tartu University Hospital Recruiting
Tartu, Estonia, 51014
HOP Général, Cardio, Abbeville Recruiting
Aix en Provence, France, 13616
HOP de Bayonne Recruiting
Bayonne Cedex, France, 64109
HOP J.Minjoz, Neuro, Besançon Recruiting
Besançon cedex, France, 25030
HOP Pellegrin Recruiting
Bordeaux cedex, France, 33076
HOP de la Cavale Blanche Recruiting
Brest, France, 29609
HOP P. Wertheimer Recruiting
Bron cedex, France, 69677
HOP Côte de Nacre Recruiting
Caen, France, 14033
HOP Grenoble, Neuro, Grenoble Recruiting
Grenoble, France, 38043
HOP Roger Salengro Recruiting
Lille cedex, France, 59037
HOP CHR Metz-Thionville, Neuro Recruiting
Metz cedex 03, France, 57085
HOP Saint-Anne Recruiting
Paris cedex 14, France, 75674
HOP Paris Saint-Joseph Recruiting
Paris, France, 75014
HOP Purpan Recruiting
Toulouse, France, 31059
Klinikum Altenburger Land GmbH Recruiting
Altenburg, Germany, 04600
Neurologische Klinik GmbH, Bad Neustadt Recruiting
Bad Neustadt/Saale, Germany, 97616
Vivantes Netzwerk für Gesundheit GmbH Recruiting
Berlin, Germany, 12351
Evangelisches Klinikum Bethel gGmbH Recruiting
Bielefeld, Germany, 33611
Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH Recruiting
Bochum, Germany, 44789
St. Josef- und St. Elisabeth-Hospital gGmbH Recruiting
Bochum, Germany, 44791
Gesundheit Nord gGmbH | Klinikverbund Bremen Recruiting
Bremen, Germany, 28177
Klinikum Bremerhaven Recruiting
Bremen, Germany, 28755
Krankenhäuser Buchholz und Winsen gGmbH Recruiting
Buchholz, Germany, 21244
Allgemeines Krankenhaus, Celle Recruiting
Celle, Germany, 29223
Klinikum Chemnitz gGmbH Recruiting
Chemnitz, Germany, 09131
Klinikum Coburg gGmbH Recruiting
Coburg, Germany, 96450
Klinikzentrum Mitte, Dortmund Recruiting
Dortmund, Germany, 44137
Städtisches Klinikum Dresden Recruiting
Dresden, Germany, 01067
Universitätsklinikum Carl Gustav Carus Dresden Recruiting
Dresden, Germany, 01307
Universitätsklinikum Düsseldorf Recruiting
Düsseldorf, Germany, 40225
Marien-Hospital, Düsseldorf Recruiting
Düsseldorf, Germany, 40479
Universitätsklinikum Erlangen Recruiting
Erlangen, Germany, 91054
Alfried Krupp Krankenhaus Essen Recruiting
Essen, Germany, 45131
Universitätsklinikum Essen AöR Recruiting
Essen, Germany, 45147
Universitätsklinikum Frankfurt Recruiting
Frankfurt am Main, Germany, 60528
Klinikum Frankfurt Höchst GmbH Recruiting
Frankfurt, Germany, 65929
Klinikum Friedrichshafen Recruiting
Friedrichshafen, Germany, 88048
Klinikum Fulda gAG Recruiting
Fulda, Germany, 36043
Evangelische Klinik Gelsenkirchen Recruiting
Gelsenkirchen, Germany, 45879
SRH Wald-Klinikum Gera GmbH Recruiting
Gera, Germany, 07548
Universitätsklinikum Gießen und Marburg GmbH Recruiting
Gießen, Germany, 35385
Universitätsmedizin Greifswald Recruiting
Greifswald, Germany, 17475
Bezirkskrankenhaus, Günzburg Recruiting
Günzburg, Germany, 89312
Asklepios Klinik St. Georg Recruiting
Hamburg, Germany, 20099
Universitätsklinikum Hamburg-Eppendorf Recruiting
Hamburg, Germany, 20246
Asklepios Klinik Harburg Recruiting
Hamburg, Germany, 21075
Asklepios Klinik Wandsbek Recruiting
Hamburg, Germany, 22043
Asklepios Klinik Barmbek Recruiting
Hamburg, Germany, 22291
Asklepios Klinik Altona Recruiting
Hamburg, Germany, 22763
Klinikum Hanau GmbH Recruiting
Hanau, Germany, 63450
Medizinische Hochschule Hannover Recruiting
Hannover, Germany, 30625
Universitätsklinikum Heidelberg Recruiting
Heidelberg, Germany, 69120
SLK-Kliniken Heilbronn GmbH Recruiting
Heilbronn, Germany, 74078
Klinikum Idar-Oberstein Recruiting
Idar-Oberstein, Germany, 55743
Universitätsklinikum Jena Recruiting
Jena, Germany, 07747
Universitätsklinikum Schleswig-Holstein, Campus Kiel Recruiting
Kiel, Germany, 24105
Universitätsklinikum Köln (AöR) Recruiting
Köln, Germany, 50937
Universitätsklinikum Leipzig Recruiting
Leipzig, Germany, 04103
Klinikum der Stadt Ludwigshafen am Rhein gGmbH Recruiting
Ludwigshafen, Germany, 67063
Universitätsklinikum Magdeburg AöR Recruiting
Magdeburg, Germany, 39120
Universitätsmedizin der Johannes Gutenberg-Universität Mainz Recruiting
Mainz, Germany, 55131
Universitätsklinikum Gießen und Marburg GmbH Recruiting
Marburg, Germany, 35043
Elblandklinikum Meißen Recruiting
Meißen, Germany, 01662
Johannes Wesling Klinikum Recruiting
Minden, Germany, 32429
Kliniken Maria Hilf GmbH Recruiting
Moenchengladbach, Germany, 41063
Ökumenisches Hainich Klinikum gGmbH Recruiting
Mühlhausen, Germany, 99974
Klinikum der Universität München - Campus Großhadern Recruiting
München, Germany, 81377
Klinikum rechts der Isar der Technischen Universität München Recruiting
München, Germany, 81675
Universitätsklinikum Münster Recruiting
Münster, Germany, 48129
Klinikum Nürnberg Süd Recruiting
Nürnberg, Germany, 90471
Klinikum Offenbach GmbH Recruiting
Offenbach, Germany, 63069
Klinikum Osnabrück GmbH Recruiting
Osnabrück, Germany, 49076
Universitätsklinikum Regensburg Recruiting
Regensburg, Germany, 93053
Nordwest-Krankenhaus Sanderbusch gGmbH Recruiting
Sande, Germany, 26452
Kreisklinikum Siegen GmbH Recruiting
Siegen, Germany, 57076
Bürgerhospital, Stuttgart Recruiting
Stuttgart, Germany, 70174
Nervenklinik Teupitz, Teupitz Recruiting
Teupitz, Germany, 15755
Krankenhaus der Barmherzigen Brüder Trier Recruiting
Trier, Germany, 54292
Universitätsklinikum Tübingen Recruiting
Tübingen, Germany, 72076
RKU - Universitäts- und Rehabilitationskliniken Ulm gGmbH Recruiting
Ulm, Germany, 89081
Sophien- und Hufeland-Klinikum gGmbH Recruiting
Weimar, Germany, 99425
Helios Kliniken Wiesbaden GmbH Recruiting
Wiesbaden, Germany, 65199
Universitätsklinikum Würzburg Recruiting
Würzburg, Germany, 97080
Univ.Hosp. of Alexandroupolis Recruiting
Alexandroupolis, Greece, 68131
Gen.Hosp.of Ath.Evangelismos Recruiting
Athens, Greece, 10676
Attikon University Hospital Recruiting
Athens, Greece, 12462
Gen.Univ. Hosp. of Herakleion Recruiting
Herakleion, Greece, 71306
Univ. Gen. Hosp. of Larissa Recruiting
Larissa, Greece, 41110
Univ. Gen. Hosp. of Patras Recruiting
Patras, Greece, 26504
Univ.Gen.Hosp. of Thessaloniki Recruiting
Thessaloniki, Greece, 54636
Hong Kong
Prince of Wales Hospital Active, not recruiting
Hong Kong, Hong Kong, 0
Pamela Youde Nethersole Eastern Hospital Active, not recruiting
Hong Kong, Hong Kong
Queen Mary Hospital Recruiting
Hong Kong, Hong Kong
Semmelweis Univ, Neurology Clinic, Budapest Recruiting
Budapest, Hungary, 1083
National Instit.of Neurosciences,Neurology Dept,Budapest Recruiting
Budapest, Hungary, 1145
Univ. Debrecen Medical Health Science Center, Neurology Dept Recruiting
Debrecen, Hungary, 4012
Pest Megyei Flor Ferenc Hospital Recruiting
Kistarcsa, Hungary, 2143
CRU Hungary Ltd, Private Practice, Miskolc Recruiting
Miskolc, Hungary, 3529
Univ. of Pecs Clinic for Neurology Recruiting
Pecs, Hungary, 7623
St. Johns medical College and Hospital Recruiting
Bangalore, India, 560034
Post Graduate Institute of Medical Education and Research Recruiting
Chandigarh, India, 160012
Lalitha Super Specialities Hospital Recruiting
Guntur, India, 522001
Nizam's Institute of Medical Sciences Recruiting
Hyderabad, India, 500082
Shree Krishna Hospital and Research Centre Recruiting
Karamsad, India, 388325
National Neurosciences Centre,Calcutta Recruiting
Kolkata, India, 700094
Caritas Hospital Recruiting
Kottayam, India, 686016
Mangala Hospital and Mangala Kidney Foundation Recruiting
Mangalore, India, 575003
LTMMC & GH Medical College, Recruiting
Mumbai, India, 400022
Magnum Heart Institute Recruiting
Nashik, India, 422005
All India Institute of Medical Science Recruiting
New Delhi, India, 110029
Sahyadri Speciality Hospital Recruiting
Pune, India, 411004
Hillel Yaffe Medical Center, Hadera Recruiting
Hadera, Israel, 38100
Wolfson Medical Center, Neurological department, Holon Recruiting
Holon, Israel, 58100
Hadassah Medical Center, Ein-Karem Recruiting
Jerusalem, Israel, 91120
The Chaim Sheba Medical Center Tel Hashomer Recruiting
Tel Hashomer, Ramat Gan, Israel, 5265601
Sourasky Medical Center Recruiting
Telaviv, Israel, 64239
Osp. SS Filippo Nicola Recruiting
Avezzano, Italy, 67051
Policlinico S. Orsola Malpighi Recruiting
Bologna, Italy, 40138
A.O. Spedali Civili di Brescia Recruiting
Brescia, Italy, 25123
Azienda Ospedaliero Universitaria di Ferrara Recruiting
Cona (FE), Italy, 44124
Policlinico San Martino Recruiting
Genova, Italy, 16132
A.O.U.Policlinico G.Martino Recruiting
Messina, Italy, 98125
Fondazione Centro San Raffaele del Monte Tabor Recruiting
Milano, Italy, 20132
Istituto Auxologico Italiano Recruiting
Milano, Italy, 20149
Nuovo Ospedale Civile S. Agostino-Estense Recruiting
Modena, Italy, 41126
Azienda Ospedaliera Universitaria di Padova Recruiting
Padova, Italy, 35128
Ospedale S.Maria della Misericordia, AO di Perugia Recruiting
Perugia, Italy, 06156
Osp. Guglielmo da Saliceto AUSL di Piacenza Recruiting
Piacenza, Italy, 29121
Ospedale Santa Corona Azienda Sanitaria Locale n.2 Savonese Recruiting
Pietra Ligure, Italy, 17027
Università degli Studi Campus Bio-Medico Recruiting
Roma, Italy, 00128
A.O. San Camillo Forlanini Recruiting
Roma, Italy, 00152
Umberto I Pol. di Roma-Università di Roma La Sapienza Recruiting
Roma, Italy, 00161
Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza Recruiting
Roma, Italy, 00189
A.O.U. Senese Policlinico Santa Maria alle Scotte Recruiting
Siena, Italy, 53100
Ospedale Molinette, AO Città della Salute e della Recruiting
Torino, Italy, 10126
Ospedale Maria Vittoria Recruiting
Torino, Italy, 10144
Ospedale S. Maria di Ca' Foncello Azienda ULSS9 TREVISO Recruiting
Treviso, Italy, 31100
A. O. Ospedale Circolo Fond. Macchi Recruiting
Varese, Italy, 21100
Ist. Ospitalieri "Borgo Trento" Recruiting
Verona, Italy, 37126
Chubu Rosai Hospital Recruiting
Aichi, Nagoya, Japan, 455-8530
National Hospital Organization Toyohashi Medical Center Recruiting
Aichi, Toyohashi, Japan, 440-8510
Toyota Memorial Hospital Recruiting
Aichi, Toyota, Japan, 471-8513
Reserch Institute for Brain and Blood Vessels Akita Recruiting
Akita, Akita, Japan, 010-0874
Juntendo University Urayasu Hospital Recruiting
Chiba, Urayasu, Japan, 279-0021
Go Neurosurgical Clinic Recruiting
Fukuoka, Chikushi-gun, Japan, 811-1244
Fukuoka University Chikushi Hospital Recruiting
Fukuoka, Chikushino, Japan, 818-8502
National Hospital Organization Kyushu Medical Center Recruiting
Fukuoka, Fukuoka, Japan, 810-8563
Fukuoka Wajiro Hospital Recruiting
Fukuoka, Fukuoka, Japan, 811-0213
Fukuoka University Hospital Recruiting
Fukuoka, Fukuoka, Japan, 814-0180
Fukuoka Tokushukai Medical Center Recruiting
Fukuoka, Kasuga, Japan, 816-0864
Steel Memorial Yawata Hospital Recruiting
Fukuoka, Kitakyushu, Japan, 805-0050
Japan Community Health Care Organization Kyushu Hospital Recruiting
Fukuoka, Kitakyushu, Japan, 806-8501
St. Mary's Hospital Recruiting
Fukuoka, Kurume, Japan, 830-8543
Shin Koga Hospital Recruiting
Fukuoka, Kurume, Japan, 830-8577
Fukuoka Shin Mizumaki Hospital Recruiting
Fukuoka, Onga, Japan, 807-0051
Tagawa Hp., Fukuoka, NS Recruiting
Fukuoka, Tagawa, Japan, 826-8585
Shin Yukuhashi Hospital Recruiting
Fukuoka, Yukuhashi, Japan, 824-0026
Fujita General Hospital Recruiting
Fukushima, Date-Gun, Japan, 969-1793
Shinseikai Masu Memorial Hospital Recruiting
Fukushima, Nihonmatsu, Japan, 964-0867
Murakami Memorial Hospital Asahi University Recruiting
Gifu, Gifu, Japan, 500-8523
Japanese Red Cross Takayama Hospital Recruiting
Gifu, Takayama, Japan, 506-8550
Mihara Memorial Hospital Recruiting
Gunma, Isesaki, Japan, 372-0006
Maebashi Red Cross Hospital Recruiting
Gunma, Maebashi, Japan, 371-0014
Medical corporation Suiseikai Suiseikai Kajikawa Hospital Recruiting
Hiroshima, Hiroshima, Japan, 730-0046
Araki Neurosurgical Hospital Recruiting
Hiroshima, Hiroshima, Japan, 733-0821
Hiroshima Prefectural Hospital Recruiting
Hiroshima, Hiroshima, Japan, 734-8530
Sapporo Shiroishi Memorial Hospital Recruiting
Hokkaido, Sapporo, Japan, 003-0026
Nakamura Memorial Hospital Recruiting
Hokkaido, Sapporo, Japan, 060-8570
Kobe City Medical Center General Hospital Recruiting
Hyogo, Kobe, Japan, 650-0047
JA Toride Medical Center Recruiting
Ibaraki, Toride, Japan, 302-0022
Tsukuba Medical Center Hospital Recruiting
Ibaraki, Tsukuba, Japan, 305-8558
Iwate Medical University Hospital Recruiting
Iwate, Morioka, Japan, 020-8505
Kagoshima City Hospital Recruiting
Kagoshima, Kagoshima, Japan, 890-8760
National Hospital Organization Kagoshima Medical Center Recruiting
Kagoshima, Kagoshima, Japan, 892-0853
Shonan Kamakura General Hospital Recruiting
Kanagawa, Kamakura, Japan, 247-8533
Saiseikai Kumamoto Hospital Recruiting
Kumamoto, Kumamoto, Japan, 861-4193
Japanese Red Cross Kumamoto Hospital Recruiting
Kumamoto, Kumamoto, Japan, 861-8520
Kumamoto City Hospital Recruiting
Kumamoto, Kumamoto, Japan, 862-8505
Uji-Tokushukai Medical Center Recruiting
Kyoto, Uji, Japan, 611-0042
National Hospital Organization Sendai Medical Center Recruiting
Miyagi, Sendai, Japan, 983-8520
South Miyagi Medical Center Recruiting
Miyagi, Shibata-gun, Japan, 989-1253
Ina Central Hospital Recruiting
Nagano, Ina, Japan, 396-8555
Nagano Municipal Hospital Recruiting
Nagano, Naganoi, Japan, 381-8551
Nagasaki University Hospital Recruiting
Nagasaki, Nagasaki, Japan, 852-8501
Nozaki Tokushukai Hospital Recruiting
Osaka, Daito, Japan, 574-0074
Higashiosaka City Medical Center Recruiting
Osaka, Higashiosaka, Japan, 578-8588
Wakakusa Daiichi Hospital Recruiting
Osaka, Higashiosaka, Japan, 579-8056
Rinku General Medical Center Recruiting
Osaka, Izumisano, Japan, 598-8577
Kishiwada Tokushukai Hospital Recruiting
Osaka, Kishiwada, Japan, 596-0042
Yagi Neurosurgical Hospital Recruiting
Osaka, Osaka, Japan, 537-0011
Tominaga Hospital Recruiting
Osaka, Osaka, Japan, 556-0017
Osaka University Hospital Recruiting
Osaka, Suita, Japan, 565-0871
Asakadai Central General Hospital Recruiting
Saitama, Asaka, Japan, 315-8551
Saitama Medical University International Medical Center Recruiting
Saitama, Hidaka, Japan, 350-1298
Sainokuni Higashiomiya Medical Center Recruiting
Saitama, Saitama, Japan, 331-8577
Saitama Municipal Hospital Recruiting
Saitama, Saitama, Japan, 336-8522
Nippon Medical School Hospital Recruiting
Tokyo, Bunkyo-ku, Japan, 113-8603
Tokyo Metropolitan Geriatric Hospital Recruiting
Tokyo, Itabashi-ku, Japan, 173-0015
Kyorin University Hospital Recruiting
Tokyo, Mitaka, Japan, 181-8611
Tokyo Women's Medical University Hospital Recruiting
Tokyo, Shinjuku-ku, Japan, 162-8666
Saiseikai Wakayama Hospital Recruiting
Wakayama, Wakayama, Japan, 640-8158
Yamagata City Hospital SAISEIKAN Recruiting
Yamagata, Yamagata, Japan, 990-8533
Korea, Republic of
Hallym University Sacred Heart Hospital Recruiting
Anyang, Korea, Republic of, 431-070
Dong-A University Hospital Recruiting
Busan, Korea, Republic of, 602-715
Kyungpook National Univ. Hosp Recruiting
Daegu, Korea, Republic of, 700-721
Chungnam National University Hospital Recruiting
Daejoen, Korea, Republic of, 301721
Inje University Ilsan Paik Hospital Recruiting
Goyang, Korea, Republic of, 411-706
Chonnam National University Hospital Recruiting
Gwangju, Korea, Republic of, 501-757
Chosun University Hospital Recruiting
Gwangju, Korea, Republic of, 61453
Seoul National University Bundang Hospital Recruiting
Seongnam, Korea, Republic of, 463-707
Severance Hospital, Yonsei University Health System Recruiting
Seoul, Korea, Republic of, 120-752
Kangdong Sacred Heart Hospital Recruiting
Seoul, Korea, Republic of, 134-701
Samsung Medical Center Recruiting
Seoul, Korea, Republic of, 135-710
The Catholic University of Korea, Seoul St.Mary's Hospital Recruiting
Seoul, Korea, Republic of, 137-701
Asan Medical Center Recruiting
Seoul, Korea, Republic of, 138-736
Korea University Guro Hospital Recruiting
Seoul, Korea, Republic of, 152-703
SMG-SNU Boramae Medical Center Recruiting
Seoul, Korea, Republic of, 156-707
Chung-Ang University Hospital Recruiting
Seoul, Korea, Republic of, 156-755
Ajou University Hospital Recruiting
Suwon, Korea, Republic of, 443-380
Sarawak General Hospital Recruiting
Kuching, Malaysia, 93586
Hospital Seberang Jaya Recruiting
Pulau Pinang, Malaysia, 13700
Hospital Serdang Recruiting
Selangor, Malaysia, 43300
Hospital Sultanah Nur Zahirah Recruiting
Terengganu, Malaysia, 20400
Hospital General de Culiacán &quot;Dr. Bernardo J. Gastellum&quot; Recruiting
Culiacán, Mexico, 80230
CRI Centro Regiomontano de Investigación S.C. Recruiting
Monterrey, Mexico, 64710
Hospital General &quot;Dr. Miguel Silva&quot; Recruiting
Morelia, Mexico, 58000
Hospital Angeles del Pedregal Recruiting
México, D.F., Mexico, 10700
Hospital Universitario Dr Jose Eleuterio Gonzalez Recruiting
Nuevo Leon, Mexico, 64460
H. Central Dr Ignacio M. P. Recruiting
San Luis Potosi, Mexico, 78250
New Zealand
Auckland City Hospital Recruiting
Grafton / Auckland, New Zealand, 1010
North Shore Hospital, Takapuna Recruiting
Takpuna Auckland, New Zealand, 0622
Wellington Hospital Recruiting
Wellington, New Zealand, 6212
Hospital Nacional Carlos Alberto Seguín Escobedo Recruiting
Arequipa, Peru
Instituto Nacional de Ciencias Neurológicas Recruiting
Barrios Altos, Peru
Hospital Nacional Guillermo Almenara Irigoyen Recruiting
La Victoria, Peru, Lima-13
PI HOUSE Sp. z o.o., Gdansk Recruiting
Gdansk, Poland, 80546
Spec.Hosp.of Dr. Wladyslaw Bieganski in Grudziadz Recruiting
Grudziadz, Poland, 86300
Univ.Clin.Centr Gibinski of Silesian Med,Neurol.dep,Katowice Recruiting
Katowice, Poland, 40514
University Hospital in Krakow Recruiting
Krakow, Poland, 31503
Center of Clinical Neurology, private prac, Krakow Recruiting
Krakow, Poland, 31505
Clin.Research Center,Leszek Szczepanski,Private Prac.,Lublin Recruiting
Lublin, Poland, 20022
Medicome Sp. z o.o. Recruiting
Oswiecim, Poland, 32-600
Specialist Holy Spirit Hospital, Neurology Dept,Sandomierz Recruiting
Sandomierz, Poland, 27600
Public Central Clinical Hosp,Neurology Clinic,Warsaw Recruiting
Warsaw, Poland, 02097
Military Institute of Medicine Neurology Clinic, Warsaw Recruiting
Warsaw, Poland, 04 141
Hospital Garcia de Orta, EPE Recruiting
Almada, Portugal, 2801-951
Hospital Fernando Fonseca, EPE Recruiting
Amadora, Portugal, 2720-276
Hospital de Braga-Escala Braga Recruiting
Braga, Portugal, 4710-243
CHUC - Centro Hospitalar e Universitário de Coimbra, EPE Recruiting
Coimbra, Portugal, 3004-561
CHLC, EPE - Hospital de São José Recruiting
Lisboa, Portugal, 1150-199
CHLO, EPE - Hospital Egas Moniz Recruiting
Lisboa, Portugal, 1349-019
CHLN, EPE - Hospital de Santa Maria Recruiting
Lisboa, Portugal, 1649-035
Hospital Beatriz Ângelo Recruiting
Loures, Portugal, 2674-514
ULSM, EPE - Hospital Pedro Hispano Recruiting
Matosinhos, Portugal, 4454-509
H. Santo António - Centro Hospitalar do Porto Recruiting
Porto, Portugal, 4099-001
Centro Hospitalar São João,EPE Recruiting
Porto, Portugal, 4202-451
Centro Hospitalar de Entre o Douro e Vouga, E.P.E. - Hospital de São Sebastião Recruiting
Santa Maria da Feira, Portugal, 4520-211
Russian Federation
Interreg. Clinical & Diagnostic Center, Neurol. Dept., Kazan Recruiting
Kazan, Russian Federation, 420101
Reg.Clin.Hosp#1 na S.V.Ochapovskiy,Neurology#1 Dep,Krasnodar Recruiting
Krasnodar, Russian Federation, 350086
City Clin.Emergency Hosp of Kursk, Neurology Department No.2 Recruiting
Kursk, Russian Federation, 305035
Clin.Hosp#2,na.Semashko,Russ.Railways,Restorative Med&Rehab. Recruiting
Moscow, Russian Federation, 107150
CityClin.Hosp na I.V.Davydovsky of Dept of Healthcare Moscow Recruiting
Moscow, Russian Federation, 109240
Research&Clini Cent Neuropsychiatry Dep. Healthcare,Moscow Recruiting
Moscow, Russian Federation, 115419
City Clin.Hosp#1na N.I.Pirogov,Dept of Healthcare of Moscow Recruiting
Moscow, Russian Federation, 117049
Ltd liabilityCom.CityNeurologic Cntr Sibneiromed,Novosibirsk Recruiting
Novosibirsk, Russian Federation, 630091
Saratov State Med.Univ na V.I.Razumovsky,FacultyTherapy Clin Recruiting
Saratov, Russian Federation, 410054
Reg.State Instit.of Healthc.Smolensk Reg.Clin.Hosp,Neurology Recruiting
Smolensk, Russian Federation, 214018
Research Inst. of Emerg. Med., Vascul. Center,St. Petersburg Recruiting
St. Petersburg, Russian Federation, 192242
Military Medical Academy n.a. S. M. Kirov, St. Petersburg Recruiting
St. Petersburg, Russian Federation, 194044
Sverdlovsk Reg.Clin.Hosp.No.1 Recruiting
Yekaterinburg, Russian Federation, 620102
Clinical Center of Serbia Recruiting
Belgrade, Serbia, 11000
Clinical Center of Serbia Active, not recruiting
Belgrade, Serbia, 11000
Special Hosp.for Cerebrovascul.Disease,'Sveti Sava,Belgrade Recruiting
Belgrade, Serbia, 11000
Clinical Centre Nis Recruiting
Nis, Serbia, 18000
Clinical Center of Vojvodina Recruiting
Novi Sad, Serbia, 21000
National University Hospital Recruiting
Singapore, Singapore, 119074
Singapore General Hospital Recruiting
Singapore, Singapore, 169037
National Neuroscience Institute Recruiting
Singapore, Singapore, 308433
Faculty Hospital L. Pasteura, Kosice Recruiting
Kosice, Slovakia, 40 66
Faculty Hospital Nitra Recruiting
Nitra, Slovakia, 950 01
Instit.f.applicative Research in med.rehab.Dobrna Active, not recruiting
Dobrna, Slovenia, 3204
Cardial d.o.o., Specialist out-patient unit, Ljubljana Recruiting
Ljubljana, Slovenia, 1000
Univ. Medical Center Maribor Active, not recruiting
Maribor, Slovenia, 2000
South Africa
Iatros International Recruiting
Bloemfontein, South Africa, 9301
Dr C. Coetzee Recruiting
Gateway, South Africa, 4321
Excellentis Clinical Trials Recruiting
George, South Africa, 6529
University of Pretoria Recruiting
Pretoria, South Africa, 0002
Vergelegen Medi-Clinic Recruiting
Somerset West, South Africa, 7130
Dr. Moodley and Dr. Sarvan Recruiting
Tongaat, South Africa, 4400
Hospital General Universitario de Albacete Recruiting
Albacete, Spain, 02006
Hospital del Mar Recruiting
Barcelona, Spain, 08003
Hospital Santa Creu i Sant Pau Recruiting
Barcelona, Spain, 08025
Hospital Vall d'Hebron Recruiting
Barcelona, Spain, 08035
Hospital Universitari de Girona Doctor Josep Trueta Recruiting
Girona, Spain, 17007
Hospital Arnau de Vilanova Recruiting
Lleida, Spain, 25198
Hospital La Princesa Recruiting
Madrid, Spain, 28006
Hospital General Universitario Gregorio Marañón Recruiting
Madrid, Spain, 28007
Hospital Ramón y Cajal Recruiting
Madrid, Spain, 28034
Hospital Clínico San Carlos Recruiting
Madrid, Spain, 28040
Hospital La Paz Recruiting
Madrid, Spain, 28046
Hospital Son Espases Recruiting
Palma de Mallorca, Spain, 07010
Complejo Hospitalario de Navarra Recruiting
Pamplona, Spain, 31008
Hospital Universitario Donostia Recruiting
San Sebastian, Spain, 20014
Hospital Clínico de Santiago Recruiting
Santiago de Compostela, Spain, 15706
Hospital Virgen del Rocío Recruiting
Sevilla, Spain, 41013
Hospital Universitari Joan XXIII Recruiting
Tarragona, Spain, 43005
Hospital Mútua Terrassa Recruiting
Tarrasa (Barcelona), Spain, 08221
Hospital Clínico de Valencia Recruiting
Valencia, Spain, 46010
Hospital Clínico Universitario de Valladolid Recruiting
Valladolid, Spain, 47005
Sahlgrenska US, Göteborg Recruiting
Göteborg, Sweden, 413 45
Sahlgrenska Universitetssjukhuset, Östra Recruiting
Göteborg, Sweden, 416 85
Skaraborgs Sjukhus Recruiting
Skövde, Sweden, 541 85
Karolinska Univ. sjukhuset Recruiting
Stockholm, Sweden, 141 86
Karolinska Univ. sjukhuset Recruiting
Stockholm, Sweden, 171 76
Danderyds Sjukhus Recruiting
Stockholm, Sweden, 182 88
Canton Hospital Aarau, Neurology Dept., Stroke Center Recruiting
Aarau, Switzerland, 5001
Universitätsspital Basel Recruiting
Basel, Switzerland, 4031
Univ. Hospital Bern, Neurology Dept, Stroke Center Recruiting
Bern, Switzerland, 3010
CHUV - Centre hospitalier universitaire vaudois Recruiting
Lausanne, Switzerland, 1011
Regional Hospital Lugano,Neurocenter of Southern Switzerland Recruiting
Lugano, Switzerland, 6903
Kantonsspital St.Gallen Recruiting
St. Gallen, Switzerland, 9007
University Hosp. Zürich, Dept. of Neurology, Stroke Center Recruiting
Zürich, Switzerland, 8901
Chang-Hua Christian Hospital Active, not recruiting
Changhua, Taiwan, 500
Kaohsiung Chang Gung Memorial Hospital Recruiting
Kaohsiung, Taiwan, 83301
Kaohsiung Medical University Chung-Ho Memorial Hospital Recruiting
Kaohsiung, Taiwan, 8807
China Medical University Hospital Active, not recruiting
Taichung, Taiwan, 404
Taichung Veterans General Hospital Recruiting
Taichung, Taiwan, 40750
Chi Mei Medical Center Active, not recruiting
Tainan,, Taiwan, 71004
NCKUH Recruiting
Tainan, Taiwan, 704
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Mackay Memorial Hospital Active, not recruiting
Taipei, Taiwan, 10449
Cheng Hsin General Hospital Recruiting
Taipei, Taiwan, 112
Taipe Veterans General Hospital Recruiting
Taipei, Taiwan, 112
Tri-Service General Hospital Recruiting
Taipei, Taiwan, 11490
Chang Gung Memorial Hospital(TaoYuan) Recruiting
Taoyuan, Taiwan, 330
Chulalongkorn University Recruiting
Bangkok, Thailand, 10330
Ramathibodi Hospital Recruiting
Bangkok, Thailand, 10400
Siriraj Hospital Recruiting
Bangkok, Thailand, 10700
Lampang Hospital Recruiting
Lampang, Thailand, 52000
Ankara Universitesi Tip Fakultesi Recruiting
Ankara, Turkey, 06100
Hacettepe Universitesi Tip Fakultesi Noroloji A.B.D. Recruiting
Ankara, Turkey, 06100
Gazi Universitesi Tip Fakultesi Recruiting
Ankara, Turkey, 06500
Eskisehir Osmangazi Universitesi Tip Fakultesi Recruiting
Eskisehir, Turkey, 26480
Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi Recruiting
Istanbul, Turkey, 34093
Istanbul Universitesi Istanbul Tip Fakultesi Noroloji A.B.D. Recruiting
Istanbul, Turkey, 34093
Istanbul Universitesi Cerrahpasa Tip Fakultesi Recruiting
Istanbul, Turkey, 34098
Bakırkoy Dr. Sadi Konuk Egitim Ve Arastirma Hastanesi Recruiting
Istanbul, Turkey, 34147
Bakirkoy Prof. Dr. Mazhar Osman Ruh Sagligi ve Sinir Hastaliklari Recruiting
Istanbul, Turkey, 34147
Sisli Hamidiye Etfal Egitim ve Arastirma Hastanesi Recruiting
Istanbul, Turkey, 34371
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi Recruiting
Istanbul, Turkey, 34890
Dokuz Eylul Universitesi Tip Fakultesi Noroloji A.B.D. Recruiting
Izmir, Turkey, 35340
Ondokuz Mayis Universitesi Tip Fakultesi Active, not recruiting
Samsun, Turkey, 55139
Namik Kemal Universitesi Tip Fakultesi Recruiting
Tekirdag, Turkey, 59100
Bukovinian Med.Univ.Chernivtsi Reg.Psychiatric Hosp,Neurolog Recruiting
Chernivtsi, Ukraine, 58018
City Clinical Hospital No. 7, Kharkov Recruiting
Kharkiv, Ukraine, 76000
Instit.of Neurol,Psychiatry&amp;amp;Narcol,Vascul. Malformations Dep Recruiting
Kharkiv, Ukraine, 76000
Instit.of Gerontology na D.F.Chebotarev,Brain Vascular Path. Recruiting
Kyiv, Ukraine, 4114
Lviv Regional Clinical Hospital, Lviv Recruiting
Lviv, Ukraine, 79010
Ternopil State Med.Univ.na Gorbachevskiy,Neurology Dept N3 Recruiting
Ternopil, Ukraine, 46027
Vinnitsia Reg.Psychoneurol.Hosp.na Yushchenko,Dept.N3,Neurol Recruiting
Vinnitsia, Ukraine, 21005
Zhytomyr Reg.ClinHosp na Gerbachevskiy RegCouncil,Neurol.Dep Recruiting
Zhytomyr, Ukraine, 10002
Sponsors and Collaborators
Boehringer Ingelheim
Study Chair: Boehringer Ingelheim Boehringer Ingelheim
More Information

Responsible Party: Boehringer Ingelheim
ClinicalTrials.gov Identifier: NCT02239120     History of Changes
Other Study ID Numbers: 1160.189
2013-003444-24 ( EudraCT Number )
First Posted: September 12, 2014    Key Record Dates
Last Update Posted: January 10, 2018
Last Verified: January 2018

Additional relevant MeSH terms:
Neoplasm Metastasis
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Neoplastic Processes
Pathologic Processes
Serine Proteinase Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action