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Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome

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ClinicalTrials.gov Identifier: NCT02205021
Recruitment Status : Completed
First Posted : July 31, 2014
Last Update Posted : July 31, 2014
Sponsor:
Information provided by (Responsible Party):
Torriani, Martin,M.D., Massachusetts General Hospital

Study Description
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Brief Summary:
Accumulation of fat in the neck using tape measures has been linked to increased cardiovascular risk. The investigators' hypothesis is that detailed measures of neck fat using computed tomography will show that specific fat compartments in the neck contribute differently to cardiovascular risk.

Condition or disease Intervention/treatment
Obesity Other: No intervention

Study Design
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Study Type : Observational
Actual Enrollment : 303 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Compartmental Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome
Study Start Date : January 2014
Actual Primary Completion Date : March 2014

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Groups and Cohorts
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Group/Cohort Intervention/treatment
All subjects Other: No intervention


Outcome Measures
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Primary Outcome Measures :
  1. Relationship of specific neck compartments to cardiovascular risk [ Time Frame: 1 year between PET/CT and cardiometabolic marker measures ]
    Cardiovascular risk measures were obtained within one year of CT imaging of the neck.


Eligibility Criteria
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Ages Eligible for Study:   18 Years to 91 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Retrospective search of whole-body PET/CT examinations and consecutively selected imaging studies.
Criteria

Inclusion Criteria:

  • no history of malignancy at the time of image acquisition
  • fasting glucose measured immediately prior to PET/CT

Exclusion Criteria:

  • history of neck cancer, radiation therapy, and/or surgery
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02205021


Locations
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United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Sponsors and Collaborators
Massachusetts General Hospital
Investigators
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Principal Investigator: Martin Torriani, M.D. Massachusetts General Hospital
More Information
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Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Torriani, Martin,M.D., Assistant Professor of Radiology, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT02205021    
Other Study ID Numbers: 2012P001603
First Posted: July 31, 2014    Key Record Dates
Last Update Posted: July 31, 2014
Last Verified: July 2014
Additional relevant MeSH terms:
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Metabolic Syndrome
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases