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Trial record 1 of 1 for:    A071102
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Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

This study is currently recruiting participants.
Verified November 2017 by National Cancer Institute (NCI)
Sponsor:
ClinicalTrials.gov Identifier:
NCT02152982
First Posted: June 2, 2014
Last Update Posted: November 21, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
National Cancer Institute (NCI)
  Purpose
This randomized phase II/III trial studies how well temozolomide and veliparib work compared to temozolomide alone in treating patients with newly diagnosed glioblastoma multiforme. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether temozolomide is more effective with or without veliparib in treating glioblastoma multiforme.

Condition Intervention Phase
Glioblastoma Gliosarcoma Other: Laboratory Biomarker Analysis Other: Placebo Other: Quality-of-Life Assessment Drug: Temozolomide Drug: Veliparib Phase 2 Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Official Title: A Phase II/III Randomized Trial of Veliparib or Placebo in Combination With Adjuvant Temozolomide in Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation

Resource links provided by NLM:


Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Overall survival (OS) [ Time Frame: From study registration to the date of death due to any cause, assessed up to 10 years ]
    The distribution of OS for each arm will be estimated using the Kaplan-Meier method and compared with a stratified logrank test. Stratified Cox proportional hazard models will be used to estimate the hazard ratio for the treatment effect.


Secondary Outcome Measures:
  • Change in quality of life (QOL), measured by the fatigue/uniscale tool [ Time Frame: Baseline to up to 5 years ]
    The fatigue/uniscale tool will be used as a measure of QOL. Potential differences in fatigue levels of patients treated on the two different arms will be evaluated. Changes in this measure will be evaluated over the course of treatment for both arms and will be compared using a two-sample t-test at each timepoint. Will also compute a normalized area under the curve (AUC) for the values of each patient over time and compare the mean AUCs for patients on the two arms.

  • Interaction with Optune device [ Time Frame: Up to 5 years ]
    Cox proportional hazards model will be used to evaluate whether there is a potential interaction between the treatment arm and the Optune device. If an interaction is detected, separate analyses of treatment effect (using Cox models) will be done for patients treated with the Optune device and patients who were not treated with the Optune device.

  • Objective tumor response, defined as complete response or partial response as specified in the Revised Assessment in Neuro-Oncology criteria [ Time Frame: Up to 5 years ]
    An objective tumor response will be evaluated for each patient and the tumor response rate will be summarized for each arm and compared using the Chi-square test.

  • Overall adverse event rates for grade 3 or higher adverse events assessed using National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Up to 5 years ]
    The overall adverse event rates for grade 3 or higher adverse events will be summarized and be compared using Chi-Square or Fisher's Exact tests between treatment arms. The maximum grade for each type of treatment-related adverse event will be recorded for each patient, and frequency tables for each arm will be reviewed to determine patterns. Treatment-related adverse events will be tabulated for each arm.

  • Progression-free survival (PFS) [ Time Frame: From study registration to the date of first observation of disease progression or death due to any cause (whichever comes first), assessed up to 10 years ]
    The distribution of PFS for each arm will be estimated using the Kaplan-Meier method, and be compared using Cox proportional hazard models with all stratification factors adjusted.


Other Outcome Measures:
  • MGMT status [ Time Frame: Baseline ]
    The concordance between site-determined MGMT methylation status and central laboratory determination of MGMT status will be analyzed using the Chi-Square test of proportions and 95% confidence intervals for the proportion of tests in disagreement with the local site.


Estimated Enrollment: 440
Actual Study Start Date: December 15, 2014
Estimated Primary Completion Date: June 30, 2022 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm I (temozolomide, veliparib)
Patients receive temozolomide PO QD on days 1-5 and veliparib PO BID on days 1-7. Treatment repeats every 28 days for 6 courses in the absence of disease progression (confirmed progression) or unacceptable toxicity.
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Name: Quality of Life Assessment
Drug: Temozolomide
Given PO
Other Names:
  • CCRG-81045
  • Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-
  • M & B 39831
  • M and B 39831
  • Methazolastone
  • RP-46161
  • SCH 52365
  • Temcad
  • Temodal
  • Temodar
  • Temomedac
Drug: Veliparib
Given PO
Other Names:
  • ABT-888
  • PARP-1 inhibitor ABT-888
Placebo Comparator: Arm II (temozolomide, placebo)
Patients receive temozolomide as in Arm I and placebo PO BID on days 1-7. Treatment repeats every 28 days for 6 courses in the absence of disease progression (confirmed progression) or unacceptable toxicity.
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Placebo
Given PO
Other Names:
  • placebo therapy
  • PLCB
  • sham therapy
Other: Quality-of-Life Assessment
Ancillary studies
Other Name: Quality of Life Assessment
Drug: Temozolomide
Given PO
Other Names:
  • CCRG-81045
  • Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-
  • M & B 39831
  • M and B 39831
  • Methazolastone
  • RP-46161
  • SCH 52365
  • Temcad
  • Temodal
  • Temodar
  • Temomedac

Detailed Description:

PRIMARY OBJECTIVES:

I. Test whether the experimental combination of ABT-888 (veliparib) combined with TMZ (temozolomide), compared to the control of placebo combined with TMZ, significantly extends overall survival in newly diagnosed glioblastoma multiforme (GBM) patients with tumor MGMT promoter hypermethylation.

SECONDARY OBJECTIVES:

I. Test whether the experimental treatment significantly extends progression-free survival.

II. Test whether the experimental treatment improves objective tumor response. III. Test whether the experimental treatment is associated with significantly greater rates of grade 3 or higher adverse events.

TERTIARY OBJECTIVES:

I. Evaluate the utility of dynamic susceptibility contrast (DSC) and diffusion weighted imaging (DWI) magnetic resonance imaging (MRI) techniques in defining time to progression in the setting of a large multi-institutional clinical trial.

II. Test the concordance between site-determined MGMT methylation status and central laboratory determination of MGMT status in cases with local testing.

III. Evaluate whether genetic or epigenetic alterations in deoxyribonucleic acid (DNA) repair or replication genes are associated with overall survival, progression-free survival, and objective tumor response.

IV. Test whether polymorphisms in MGMT, PARP1, or other DNA repair proteins, are associated with overall survival, progression-free survival, objective tumor response, or rates of grade 3 or higher adverse events.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive temozolomide orally (PO) once daily (QD) on days 1-5 and veliparib PO twice daily (BID) on days 1-7. Treatment repeats every 28 days for 6 courses in the absence of disease progression (confirmed progression) or unacceptable toxicity.

ARM II: Patients receive temozolomide as in Arm I and placebo PO BID on days 1-7. Treatment repeats every 28 days for 6 courses in the absence of disease progression (confirmed progression) or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 3 years, every 6 months for 2 years.

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Histologic documentation: newly diagnosed World Health Organization (WHO) grade IV intracranial glioblastoma or gliosarcoma; GBM with oligodendroglial features are NOT PERMITTED in this study if they are 1p19q codeleted; sites submitting GBM with oligodendroglial features will be asked to provide results of 1p/19q codeletion status
  • Sufficient tissue available for central pathology review and MGMT methylation status evaluation
  • Patients who have had a local MGMT testing that is unmethylated are not allowed to participate
  • Tumor MGMT promoter hypermethylation determined by central testing at MD Anderson
  • Confirmation by central pathology review of WHO grade IV glioblastoma or gliosarcoma
  • Absolute neutrophil count (ANC) >= 1500 cells/mm^3 within 14 days prior to study registration
  • Platelets >= 100,000 cells/mm^3 within 14 days prior to study registration
  • Creatinine =< 1.5 x upper limit of normal (ULN) within 14 days prior to study registration
  • Bilirubin =< 1.5 x ULN within 14 days prior to study registration; unless patient has Gilbert's disease
  • Alanine aminotransferase (ALT) =< 3 x ULN within 14 days prior to study registration
  • Aspartate aminotransferase (AST) =< 3 x ULN within 14 days prior to study registration
  • Eastern Cooperative Oncology Group (ECOG) performance status =< 2
  • Measurable disease or non-measurable disease; extent of resection: patients with complete resection, partial resection, or biopsy are eligible
  • Progression: patients deemed to have progressive disease based on clinical deterioration after chemoradiation or radiographic progression outside of the radiation field are not eligible; patients deemed to have pseudoprogression are eligible
  • Prior treatment:

    • Must have completed standard radiotherapy and concomitant TMZ therapy as defined and determined by the study oncologist
    • Besides concomitant TMZ with radiation, no other therapy (neo-adjuvant or adjuvant) can be given prior to study registration, including chemotherapy (also including Gliadel/carmustine [BCNU] wafers), biologics, immunotherapy, radiation therapy; the only exception is the Optune device (NovoTTF-100A), which may be started any time after end of radiation therapy up through the initiation of Cycle 1; intent to use Optune must be declared at registration for stratification
  • Not pregnant and not nursing; females of childbearing potential must have negative urine or serum pregnancy test within 7 days of registration but before start of treatment; a female of childbearing potential is a sexually mature female who:

    • Has not undergone a hysterectomy or bilateral oophorectomy; or
    • Has not been naturally postmenopausal for at least 12 consecutive months (i.e., has had menses at any time in the preceding 12 consecutive months)
  • Concomitant medications: patients receiving anticoagulation should be on stable dose 2 weeks prior to registration
  • Comorbid conditions: patients are unable to participate due to the following:

    • Generalized or partial seizure disorder that is uncontrolled at the time of registration; the definition of controlled generalized seizures is patients must be on a stable dose of anti-seizure medication and without generalized seizures for at least 10 days prior to registration; the definition of controlled partial seizures is patients must be on a stable dose of anti-seizure medication for at least 10 days prior to registration; patients with occasional breakthrough partial seizures are allowed at treating physician's discretion
    • Grade 3 or 4 thromboembolic disease within 6 months (mo) of registration
    • Known history of prolonged QT syndrome
  • No history of major surgery =< 14 days prior to registration
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02152982


  Hide Study Locations
Locations
United States, Alabama
University of Alabama at Birmingham Cancer Center Recruiting
Birmingham, Alabama, United States, 35233
Contact: John B. Fiveash    800-828-8816      
Principal Investigator: John B. Fiveash         
United States, Alaska
Katmai Oncology Group Recruiting
Anchorage, Alaska, United States, 99508
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Alaska Medical Center Recruiting
Anchorage, Alaska, United States, 99508
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
United States, Arizona
Mayo Clinic in Arizona Recruiting
Scottsdale, Arizona, United States, 85259
Contact: Jann N. Sarkaria    855-776-0015      
Principal Investigator: Jann N. Sarkaria         
The University of Arizona Medical Center-University Campus Recruiting
Tucson, Arizona, United States, 85724
Contact: Baldassarre Stea    520-626-9008      
Principal Investigator: Baldassarre Stea         
United States, Arkansas
University of Arkansas for Medical Sciences Recruiting
Little Rock, Arkansas, United States, 72205
Contact: Shirley S. Ong    501-686-8274      
Principal Investigator: Shirley S. Ong         
United States, California
Kaiser Permanente-Deer Valley Medical Center Recruiting
Antioch, California, United States, 94531
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Providence Saint Joseph Medical Center/Disney Family Cancer Center Recruiting
Burbank, California, United States, 91505
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Mills-Peninsula Medical Center Recruiting
Burlingame, California, United States, 94010
Contact: Stacy D. D'Andre    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Stacy D. D'Andre         
John Muir Medical Center-Concord Campus Recruiting
Concord, California, United States, 94520
Contact: Marjaneh Moini    925-674-2580      
Principal Investigator: Marjaneh Moini         
Kaiser Permanente-Fremont Recruiting
Fremont, California, United States, 94538
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Fresno Cancer Center Recruiting
Fresno, California, United States, 93720
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente Recruiting
Fresno, California, United States, 93720
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Saint Jude Medical Center Recruiting
Fullerton, California, United States, 92835
Contact: William E. Lawler    714-446-5642      
Principal Investigator: William E. Lawler         
UC San Diego Moores Cancer Center Suspended
La Jolla, California, United States, 92093
Kaiser Permanente Los Angeles Medical Center Recruiting
Los Angeles, California, United States, 90027
Contact: Richard M. Green    626-564-3455      
Principal Investigator: Richard M. Green         
Los Angeles County-USC Medical Center Recruiting
Los Angeles, California, United States, 90033
Contact: Naveed Wagle    323-865-0451      
Principal Investigator: Naveed Wagle         
USC / Norris Comprehensive Cancer Center Recruiting
Los Angeles, California, United States, 90033
Contact: Naveed Wagle    323-865-0451      
Principal Investigator: Naveed Wagle         
Kaiser Permanente-Modesto Recruiting
Modesto, California, United States, 95356
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
USC Norris Oncology/Hematology-Newport Beach Recruiting
Newport Beach, California, United States, 92663
Contact: Naveed Wagle    323-865-0451      
Principal Investigator: Naveed Wagle         
Kaiser Permanente Oakland-Broadway Recruiting
Oakland, California, United States, 94611
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Oakland Recruiting
Oakland, California, United States, 94611
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Saint Joseph Hospital - Orange Recruiting
Orange, California, United States, 92868
Contact: Timothy E. Byun    714-734-6220      
Principal Investigator: Timothy E. Byun         
Kaiser Permanente-Rancho Cordova Cancer Center Recruiting
Rancho Cordova, California, United States, 95670
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Redwood City Recruiting
Redwood City, California, United States, 94063
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Richmond Recruiting
Richmond, California, United States, 94801
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Rohnert Park Cancer Center Recruiting
Rohnert Park, California, United States, 94928
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Roseville Recruiting
Roseville, California, United States, 95661
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
The Permanente Medical Group-Roseville Radiation Oncology Recruiting
Roseville, California, United States, 95678
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Sutter Medical Center Sacramento Recruiting
Sacramento, California, United States, 95816
Contact: Stacy D. D'Andre    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Stacy D. D'Andre         
University of California Davis Comprehensive Cancer Center Recruiting
Sacramento, California, United States, 95817
Contact: Robert T. O'Donnell    916-734-3089      
Principal Investigator: Robert T. O'Donnell         
Kaiser Permanente-South Sacramento Recruiting
Sacramento, California, United States, 95823
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
South Sacramento Cancer Center Recruiting
Sacramento, California, United States, 95823
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente - Sacramento Recruiting
Sacramento, California, United States, 95825
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
University of California San Diego Recruiting
San Diego, California, United States, 92103
Contact: David E. Piccioni    858-822-5354    cancercto@ucsd.edu   
Principal Investigator: David E. Piccioni         
Kaiser Permanente-San Francisco Recruiting
San Francisco, California, United States, 94115
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
UCSF Medical Center-Parnassus Recruiting
San Francisco, California, United States, 94143
Contact: Nicholas A. Butowski    877-827-3222      
Principal Investigator: Nicholas A. Butowski         
Kaiser Permanente-Santa Teresa-San Jose Recruiting
San Jose, California, United States, 95119
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente San Leandro Recruiting
San Leandro, California, United States, 94577
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-San Rafael Recruiting
San Rafael, California, United States, 94903
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente Medical Center - Santa Clara Recruiting
Santa Clara, California, United States, 95051
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Palo Alto Medical Foundation-Santa Cruz Recruiting
Santa Cruz, California, United States, 95065
Contact: Stacy D. D'Andre    415-209-2686    bernicl@sutterhealth.org   
Principal Investigator: Stacy D. D'Andre         
Kaiser Permanente-Santa Rosa Recruiting
Santa Rosa, California, United States, 95403
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente Cancer Treatment Center Recruiting
South San Francisco, California, United States, 94080
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-South San Francisco Recruiting
South San Francisco, California, United States, 94080
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Stockton Recruiting
Stockton, California, United States, 95210
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Northbay Cancer Center Suspended
Vacaville, California, United States, 95687
Kaiser Permanente Medical Center-Vacaville Recruiting
Vacaville, California, United States, 95688
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Vallejo Recruiting
Vallejo, California, United States, 94589
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
Kaiser Permanente-Walnut Creek Recruiting
Walnut Creek, California, United States, 94596
Contact: Tatjana Kolevska    510-891-3400      
Principal Investigator: Tatjana Kolevska         
John Muir Medical Center-Walnut Creek Recruiting
Walnut Creek, California, United States, 94598
Contact: Marjaneh Moini    925-674-2580      
Principal Investigator: Marjaneh Moini         
United States, Colorado
University of Colorado Hospital Recruiting
Aurora, Colorado, United States, 80045
Contact: Denise M. Damek    720-848-0650      
Principal Investigator: Denise M. Damek         
Boulder Community Hospital Recruiting
Boulder, Colorado, United States, 80301
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Rocky Mountain Cancer Centers-Boulder Recruiting
Boulder, Colorado, United States, 80304
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Penrose-Saint Francis Healthcare Recruiting
Colorado Springs, Colorado, United States, 80907
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Rocky Mountain Cancer Centers-Penrose Recruiting
Colorado Springs, Colorado, United States, 80907
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Kaiser Permanente-Franklin Recruiting
Denver, Colorado, United States, 80205
Contact: Alexander Menter    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Alexander Menter         
Swedish Medical Center Recruiting
Englewood, Colorado, United States, 80113
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Poudre Valley Hospital Recruiting
Fort Collins, Colorado, United States, 80524
Contact: Denise M. Damek    720-848-0650      
Principal Investigator: Denise M. Damek         
North Colorado Medical Center Recruiting
Greeley, Colorado, United States, 80631
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Rocky Mountain Cancer Centers-Littleton Recruiting
Littleton, Colorado, United States, 80120
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
Littleton Adventist Hospital Recruiting
Littleton, Colorado, United States, 80122
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Kaiser Permanente-Lone Tree Recruiting
Lone Tree, Colorado, United States, 80124
Contact: Alexander Menter    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Alexander Menter         
Rocky Mountain Cancer Centers-Longmont Recruiting
Longmont, Colorado, United States, 80501
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
McKee Medical Center Recruiting
Loveland, Colorado, United States, 80539
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
SCL Health Lutheran Medical Center Recruiting
Wheat Ridge, Colorado, United States, 80033
Contact: Keren Sturtz    303-777-2663    ccrp@co-cancerresearch.org   
Principal Investigator: Keren Sturtz         
United States, Connecticut
Hartford Hospital Recruiting
Hartford, Connecticut, United States, 06102
Contact: William J. Baker    860-545-5363      
Principal Investigator: William J. Baker         
Smilow Cancer Hospital Care Center at Saint Francis Recruiting
Hartford, Connecticut, United States, 06105
Contact: James J. Vredenburgh    860-714-4680      
Principal Investigator: James J. Vredenburgh         
Yale University Recruiting
New Haven, Connecticut, United States, 06520
Contact: James J. Vredenburgh    860-714-4680      
Principal Investigator: James J. Vredenburgh         
United States, Florida
Boca Raton Regional Hospital Recruiting
Boca Raton, Florida, United States, 33486
Contact: Sajeel A. Chowdhary    561-955-4800      
Principal Investigator: Sajeel A. Chowdhary         
UM Sylvester Comprehensive Cancer Center at Deerfield Beach Recruiting
Deerfield Beach, Florida, United States, 33442
Contact: Macarena I. De La Fuente    305-243-2647      
Principal Investigator: Macarena I. De La Fuente         
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Recruiting
Hollywood, Florida, United States, 33021
Contact: Atif M. Hussein    954-265-4325      
Principal Investigator: Atif M. Hussein         
Mayo Clinic in Florida Recruiting
Jacksonville, Florida, United States, 32224-9980
Contact: Jann N. Sarkaria    855-776-0015      
Principal Investigator: Jann N. Sarkaria         
Lakeland Regional Health Hollis Cancer Center Suspended
Lakeland, Florida, United States, 33805
Mount Sinai Medical Center Suspended
Miami Beach, Florida, United States, 33140
University of Miami Miller School of Medicine-Sylvester Cancer Center Recruiting
Miami, Florida, United States, 33136
Contact: Macarena I. De La Fuente    305-243-2647      
Principal Investigator: Macarena I. De La Fuente         
UF Cancer Center at Orlando Health Recruiting
Orlando, Florida, United States, 32806
Contact: Nicholas G. Avgeropoulos    321-841-7246    CancerClinicalTrials@orlandohealth.com   
Principal Investigator: Nicholas G. Avgeropoulos         
Memorial Hospital West Recruiting
Pembroke Pines, Florida, United States, 33028
Contact: Atif M. Hussein    954-265-4325      
Principal Investigator: Atif M. Hussein         
Moffitt Cancer Center Suspended
Tampa, Florida, United States, 33612
United States, Georgia
Piedmont Hospital Recruiting
Atlanta, Georgia, United States, 30309
Contact: Erin M. Dunbar    404-425-7943    ORS@piedmont.org   
Principal Investigator: Erin M. Dunbar         
Emory University Hospital/Winship Cancer Institute Recruiting
Atlanta, Georgia, United States, 30322
Contact: Jeffrey J. Olson    404-778-1868      
Principal Investigator: Jeffrey J. Olson         
Northside Hospital Recruiting
Atlanta, Georgia, United States, 30342
Contact: Lijo Simpson    404-501-3279      
Principal Investigator: Lijo Simpson         
John B Amos Cancer Center Recruiting
Columbus, Georgia, United States, 31904
Contact: Andrew W. Pippas    706-660-6404      
Principal Investigator: Andrew W. Pippas         
Northeast Georgia Medical Center-Gainesville Recruiting
Gainesville, Georgia, United States, 30501
Contact: Charles H. Nash    770-219-8800    cancerpatient.navigator@nghs.com   
Principal Investigator: Charles H. Nash         
United States, Hawaii
Hawaii Cancer Care Inc-POB II Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Oncology Inc-POB I Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Queen's Medical Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Straub Clinic and Hospital Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Cancer Care Inc-Liliha Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Hawaii Oncology Inc-Kuakini Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Recruiting
Boise, Idaho, United States, 83706
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Kootenai Cancer Center Recruiting
Post Falls, Idaho, United States, 83854
Contact: Benjamin T. Marchello    406-969-6060    mccinfo@mtcancer.org   
Principal Investigator: Benjamin T. Marchello         
United States, Illinois
Saint Joseph Medical Center Suspended
Bloomington, Illinois, United States, 61701
Northwestern University Recruiting
Chicago, Illinois, United States, 60611
Contact: Priya U. Kumthekar    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Priya U. Kumthekar         
Rush University Medical Center Recruiting
Chicago, Illinois, United States, 60612
Contact: Clement Pillainayagam    312-942-5498    clinical_trials@rush.edu   
Principal Investigator: Clement Pillainayagam         
Cancer Care Center of Decatur Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Crossroads Cancer Center Recruiting
Effingham, Illinois, United States, 62401
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
NorthShore University HealthSystem-Evanston Hospital Recruiting
Evanston, Illinois, United States, 60201
Contact: Ryan T. Merrell    847-570-2109      
Principal Investigator: Ryan T. Merrell         
Northwestern Medicine Cancer Center Delnor Recruiting
Geneva, Illinois, United States, 60134
Contact: Sean A. Grimm    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Sean A. Grimm         
NorthShore University HealthSystem-Glenbrook Hospital Recruiting
Glenview, Illinois, United States, 60026
Contact: Ryan T. Merrell    847-570-2109      
Principal Investigator: Ryan T. Merrell         
NorthShore University HealthSystem-Highland Park Hospital Recruiting
Highland Park, Illinois, United States, 60035
Contact: Ryan T. Merrell    847-570-2109      
Principal Investigator: Ryan T. Merrell         
Edward Hospital/Cancer Center Recruiting
Naperville, Illinois, United States, 60540
Contact: William R. Broderick    630-646-6075      
Principal Investigator: William R. Broderick         
Advocate Lutheran General Hospital Recruiting
Park Ridge, Illinois, United States, 60068
Contact: James E. Ruffer    847-384-3621      
Principal Investigator: James E. Ruffer         
Methodist Medical Center of Illinois Recruiting
Peoria, Illinois, United States, 61603
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
OSF Saint Francis Medical Center Recruiting
Peoria, Illinois, United States, 61637
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Edward Hospital/Cancer Center?Plainfield Recruiting
Plainfield, Illinois, United States, 60585
Contact: William R. Broderick    630-646-6075      
Principal Investigator: William R. Broderick         
Central Illinois Hematology Oncology Center Suspended
Springfield, Illinois, United States, 62702
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Carle Cancer Center Recruiting
Urbana, Illinois, United States, 61801
Contact: Yujie Zhao    630-978-6212    Cancer.Research@rushcopley.com   
Principal Investigator: Yujie Zhao         
Northwestern Medicine Cancer Center Warrenville Recruiting
Warrenville, Illinois, United States, 60555
Contact: Sean A. Grimm    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Sean A. Grimm         
United States, Indiana
Franciscan Health Indianapolis Recruiting
Indianapolis, Indiana, United States, 46237
Contact: Stephen E. Rubenstein    317-528-7060      
Principal Investigator: Stephen E. Rubenstein         
Reid Health Recruiting
Richmond, Indiana, United States, 47374
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Memorial Hospital of South Bend Suspended
South Bend, Indiana, United States, 46601
United States, Iowa
Physicians' Clinic of Iowa PC Recruiting
Cedar Rapids, Iowa, United States, 52402
Contact: William P. Fusselman    319-297-2900    cetscheidt@pcofiowa.com   
Principal Investigator: William P. Fusselman         
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    515-239-2621      
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Mercy Medical Center - Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Mercy Medical Center - North Iowa Suspended
Mason City, Iowa, United States, 50401
Siouxland Regional Cancer Center Suspended
Sioux City, Iowa, United States, 51101
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
United States, Kansas
Cancer Center of Kansas - Chanute Recruiting
Chanute, Kansas, United States, 66720
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Dodge City Recruiting
Dodge City, Kansas, United States, 67801
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - El Dorado Recruiting
El Dorado, Kansas, United States, 67042
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Fort Scott Recruiting
Fort Scott, Kansas, United States, 66701
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Independence Recruiting
Independence, Kansas, United States, 67301
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Kingman Recruiting
Kingman, Kansas, United States, 67068
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Liberal Recruiting
Liberal, Kansas, United States, 67905
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - McPherson Recruiting
McPherson, Kansas, United States, 67460
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Newton Recruiting
Newton, Kansas, United States, 67114
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Menorah Medical Center Suspended
Overland Park, Kansas, United States, 66209
Cancer Center of Kansas - Parsons Recruiting
Parsons, Kansas, United States, 67357
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Pratt Recruiting
Pratt, Kansas, United States, 67124
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Salina Recruiting
Salina, Kansas, United States, 67401
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Wellington Recruiting
Wellington, Kansas, United States, 67152
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Wichita Medical Arts Tower Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Wichita Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Via Christi Regional Medical Center Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Winfield Recruiting
Winfield, Kansas, United States, 67156
Contact: Shaker R. Dakhil    316-268-5374      
Principal Investigator: Shaker R. Dakhil         
United States, Kentucky
Baptist Health Lexington Recruiting
Lexington, Kentucky, United States, 40503
Contact: Arvinda Padmanabhan    859-260-6425      
Principal Investigator: Arvinda Padmanabhan         
University of Kentucky/Markey Cancer Center Recruiting
Lexington, Kentucky, United States, 40536
Contact: John L. Villano    859-257-3379      
Principal Investigator: John L. Villano         
Baptist Health Madisonville/Merle Mahr Cancer Center Recruiting
Madisonville, Kentucky, United States, 42431
Contact: Arvinda Padmanabhan    859-260-6425      
Principal Investigator: Arvinda Padmanabhan         
Baptist Health Paducah Recruiting
Paducah, Kentucky, United States, 42003
Contact: Arvinda Padmanabhan    859-260-6425      
Principal Investigator: Arvinda Padmanabhan         
United States, Louisiana
The NeuroMedical Center-Clinic Active, not recruiting
Baton Rouge, Louisiana, United States, 70810
Ochsner Medical Center Jefferson Recruiting
New Orleans, Louisiana, United States, 70121
Contact: Zoe L. Larned    504-842-3708      
Principal Investigator: Zoe L. Larned         
United States, Maine
Eastern Maine Medical Center Recruiting
Bangor, Maine, United States, 04401
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Lafayette Family Cancer Center-EMMC Recruiting
Brewer, Maine, United States, 04412
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Maine Center for Cancer Medicine-Scarborough Recruiting
Scarborough, Maine, United States, 04074
Contact: Devon L. Evans    207-396-8090    wrighd@mmc.org   
Principal Investigator: Devon L. Evans         
United States, Maryland
Anne Arundel Medical Center Recruiting
Annapolis, Maryland, United States, 21401
Contact: Peter R. Graze    443-481-1320    kbodenhorn@aahs.org   
Principal Investigator: Peter R. Graze         
Sinai Hospital of Baltimore Recruiting
Baltimore, Maryland, United States, 21215
Contact: Marvin J. Feldman    410-951-7950    prc@mdmercy.com   
Principal Investigator: Marvin J. Feldman         
Northwest Hospital Center Recruiting
Randallstown, Maryland, United States, 21133
Contact: Marvin J. Feldman    410-951-7950    prc@mdmercy.com   
Principal Investigator: Marvin J. Feldman         
Peninsula Regional Medical Center Recruiting
Salisbury, Maryland, United States, 21801
Contact: Justinian R. Ngaiza    866-922-6237      
Principal Investigator: Justinian R. Ngaiza         
United States, Massachusetts
Massachusetts General Hospital Cancer Center Recruiting
Boston, Massachusetts, United States, 02114
Contact: Patrick Y. Wen    877-726-5130      
Principal Investigator: Patrick Y. Wen         
Dana-Farber Cancer Institute Recruiting
Boston, Massachusetts, United States, 02215
Contact: Patrick Y. Wen    877-726-5130      
Principal Investigator: Patrick Y. Wen         
Simonds-Sinon Regional Cancer Center Suspended
Fitchburg, Massachusetts, United States, 01420
University of Massachusetts Medical School Suspended
Worcester, Massachusetts, United States, 01655
United States, Michigan
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106-0995
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Green Bay Oncology - Escanaba Recruiting
Escanaba, Michigan, United States, 49829
Contact: Anthony J. Jaslowski    920-433-8889    Christy.Gilchrist@hshs.org   
Principal Investigator: Anthony J. Jaslowski         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Mercy Health Saint Mary's Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Spectrum Health at Butterworth Campus Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Green Bay Oncology - Iron Mountain Suspended
Iron Mountain, Michigan, United States, 49801
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Assarian Cancer Center Recruiting
Novi, Michigan, United States, 48374-1236
Contact: Michael J. Kraut    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Michael J. Kraut         
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Spectrum Health Reed City Hospital Recruiting
Reed City, Michigan, United States, 49677
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
William Beaumont Hospital-Royal Oak Recruiting
Royal Oak, Michigan, United States, 48073
Contact: Joseph M. Anderson    248-551-7695      
Principal Investigator: Joseph M. Anderson         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Lakeland Hospital Recruiting
Saint Joseph, Michigan, United States, 49085
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Marie Yeager Cancer Center Recruiting
Saint Joseph, Michigan, United States, 49085
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
Providence Hospital-Southfield Cancer Center Recruiting
Southfield, Michigan, United States, 48075
Contact: Michael J. Kraut    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Michael J. Kraut         
Munson Medical Center Recruiting
Traverse City, Michigan, United States, 49684
Contact: Kathleen J. Yost    616-391-1230    crcwm-regulatory@crcwm.org   
Principal Investigator: Kathleen J. Yost         
United States, Minnesota
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Essentia Health Cancer Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Bret E. Friday    888-203-7267      
Principal Investigator: Bret E. Friday         
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Health Partners Inc Recruiting
Minneapolis, Minnesota, United States, 55454
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Mayo Clinic Recruiting
Rochester, Minnesota, United States, 55905
Contact: Jann N. Sarkaria    855-776-0015      
Principal Investigator: Jann N. Sarkaria         
Coborn Cancer Center at Saint Cloud Hospital Recruiting
Saint Cloud, Minnesota, United States, 56303
Contact: Donald J. Jurgens    877-229-4907      
Principal Investigator: Donald J. Jurgens         
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
Minnesota Oncology Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: Daniel M. Anderson    952-993-1517    mmcorc@healthpartners.com   
Principal Investigator: Daniel M. Anderson         
United States, Mississippi
University of Mississippi Medical Center Recruiting
Jackson, Mississippi, United States, 39216
Contact: Mark D. Anderson    601-815-6700      
Principal Investigator: Mark D. Anderson         
United States, Missouri
Southeast Cancer Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Saint Luke's Hospital Recruiting
Chesterfield, Missouri, United States, 63017
Contact: Donald F. Busiek    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Donald F. Busiek         
Centerpoint Medical Center LLC Suspended
Independence, Missouri, United States, 64057
Saint Luke's Hospital of Kansas City Recruiting
Kansas City, Missouri, United States, 64111
Contact: Timothy J. Pluard    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Timothy J. Pluard         
Saint Luke's East - Lee's Summit Recruiting
Lee's Summit, Missouri, United States, 64086
Contact: Timothy J. Pluard    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Timothy J. Pluard         
Washington University School of Medicine Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Jian L. Campian    800-600-3606    info@siteman.wustl.edu   
Principal Investigator: Jian L. Campian         
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: James L. Wade    309-243-3605      
Principal Investigator: James L. Wade         
Mercy Hospital Saint Louis Recruiting
Saint Louis, Missouri, United States, 63141
Contact: Jay W. Carlson    888-221-4849      
Principal Investigator: Jay W. Carlson         
Mercy Hospital Springfield Recruiting
Springfield, Missouri, United States, 65804
Contact: Jay W. Carlson    888-221-4849      
Principal Investigator: Jay W. Carlson         
CoxHealth South Hospital Recruiting
Springfield, Missouri, United States, 65807
Contact: Jay W. Carlson    888-221-4849      
Principal Investigator: Jay W. Carlson         
United States, Montana
Billings Clinic Cancer Center Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin T. Marchello    406-969-6060    mccinfo@mtcancer.org   
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Benjamin T. Marchello    406-969-6060    mccinfo@mtcancer.org   
Principal Investigator: Benjamin T. Marchello         
United States, Nebraska
CHI Health Saint Francis Recruiting
Grand Island, Nebraska, United States, 68803
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
CHI Health Good Samaritan Recruiting
Kearney, Nebraska, United States, 68847
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Faith Regional Medical Offices West Recruiting
Norfolk, Nebraska, United States, 68701
Contact: Gamini S. Soori    402-991-8070    mwilwerding@canceralliance-ne.org   
Principal Investigator: Gamini S. Soori         
Nebraska Methodist Hospital Recruiting
Omaha, Nebraska, United States, 68114
Contact: Robert M. Langdon    402-354-5144      
Principal Investigator: Robert M. Langdon         
Alegent Health Immanuel Medical Center Recruiting
Omaha, Nebraska, United States, 68122
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Alegent Health Bergan Mercy Medical Center Recruiting
Omaha, Nebraska, United States, 68124
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
Oncology Hematology West Recruiting
Omaha, Nebraska, United States, 68124
Contact: Gamini S. Soori    402-991-8070    mwilwerding@canceralliance-ne.org   
Principal Investigator: Gamini S. Soori         
Creighton University Medical Center Recruiting
Omaha, Nebraska, United States, 68131
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
University of Nebraska Medical Center Suspended
Omaha, Nebraska, United States, 68198
United States, New Hampshire
New Hampshire Oncology Hematology PA-Concord Recruiting
Concord, New Hampshire, United States, 03301
Contact: Douglas J. Weckstein    603-663-1800      
Principal Investigator: Douglas J. Weckstein         
New Hampshire Oncology Hematology PA-Hooksett Recruiting
Hooksett, New Hampshire, United States, 03106
Contact: Douglas J. Weckstein    603-663-1800      
Principal Investigator: Douglas J. Weckstein         
Dartmouth Hitchcock Medical Center Recruiting
Lebanon, New Hampshire, United States, 03756
Contact: Lara J. Kunschner-Ronan    800-639-6918    cancer.research.nurse@dartmouth.edu   
Principal Investigator: Lara J. Kunschner-Ronan         
Portsmouth Regional Hospital Suspended
Portsmouth, New Hampshire, United States, 03802
United States, New Jersey
Hackensack University Medical Center Recruiting
Hackensack, New Jersey, United States, 07601
Contact: Samuel A. Goldlust    201-996-2879      
Principal Investigator: Samuel A. Goldlust         
Saint Barnabas Medical Center Recruiting
Livingston, New Jersey, United States, 07039
Contact: Miguel A. Conde    973-322-2470      
Principal Investigator: Miguel A. Conde         
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital Recruiting
New Brunswick, New Jersey, United States, 08903
Contact: Robert D. Aiken    732-235-8675      
Principal Investigator: Robert D. Aiken         
Rutgers Cancer Institute of New Jersey Recruiting
New Brunswick, New Jersey, United States, 08903
Contact: Robert D. Aiken    732-235-8675      
Principal Investigator: Robert D. Aiken         
The Valley Hospital-Luckow Pavilion Recruiting
Paramus, New Jersey, United States, 07652
Contact: Eli D. Kirshner    201-634-5792    cparish@valleyhealth.com   
Principal Investigator: Eli D. Kirshner         
Valley Hospital Recruiting
Ridgewood, New Jersey, United States, 07450
Contact: Eli D. Kirshner    201-634-5792    cparish@valleyhealth.com   
Principal Investigator: Eli D. Kirshner         
Valley Health System-Hematology/Oncology Recruiting
Westwood, New Jersey, United States, 07675
Contact: Eli D. Kirshner    201-634-5792    cparish@valleyhealth.com   
Principal Investigator: Eli D. Kirshner         
United States, New York
Montefiore Medical Center - Moses Campus Recruiting
Bronx, New York, United States, 10467-2490
Contact: Nitin Ohri    718-904-2730    aecc@aecom.yu.edu   
Principal Investigator: Nitin Ohri         
Roswell Park Cancer Institute Recruiting
Buffalo, New York, United States, 14263
Contact: Ajay P. Abad    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: Ajay P. Abad         
Mary Imogene Bassett Hospital Recruiting
Cooperstown, New York, United States, 13326
Contact: Eric Bravin    607-547-3073    diana.crean@bassett.org   
Principal Investigator: Eric Bravin         
University of Rochester Suspended
Rochester, New York, United States, 14642
State University of New York Upstate Medical University Recruiting
Syracuse, New York, United States, 13210
Contact: Mijung Lee    315-464-5476      
Principal Investigator: Mijung Lee         
United States, North Carolina
Mission Hospital-Memorial Campus Recruiting
Asheville, North Carolina, United States, 28801
Contact: Christopher H. Chay    828-213-4150      
Principal Investigator: Christopher H. Chay         
East Carolina University Recruiting
Greenville, North Carolina, United States, 27858
Contact: Andrew W. Ju    252-744-2391      
Principal Investigator: Andrew W. Ju         
Kinston Medical Specialists PA Suspended
Kinston, North Carolina, United States, 28501
Wake Forest University Health Sciences Suspended
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Roger Maris Cancer Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Sanford Broadway Medical Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Sanford Clinic North-Fargo Suspended
Fargo, North Dakota, United States, 58122
Altru Cancer Center Recruiting
Grand Forks, North Dakota, United States, 58201
Contact: Grant R. Seeger    855-776-0015      
Principal Investigator: Grant R. Seeger         
United States, Ohio
Akron General Medical Center Recruiting
Akron, Ohio, United States, 44307
Contact: Esther H. Rehmus    330-344-6348      
Principal Investigator: Esther H. Rehmus         
Mercy Medical Center Recruiting
Canton, Ohio, United States, 44708
Contact: Mitchell Haut    888-293-4673      
Principal Investigator: Mitchell Haut         
Adena Regional Medical Center Recruiting
Chillicothe, Ohio, United States, 45601
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
University of Cincinnati/Barrett Cancer Center Recruiting
Cincinnati, Ohio, United States, 45219
Contact: Rekha T. Chaudhary    513-558-4553    uchealthnews@uc.edu   
Principal Investigator: Rekha T. Chaudhary         
Cleveland Clinic Foundation Recruiting
Cleveland, Ohio, United States, 44195
Contact: David M. Peereboom    866-223-8100      
Principal Investigator: David M. Peereboom         
Ohio State University Comprehensive Cancer Center Recruiting
Columbus, Ohio, United States, 43210
Contact: Vinay Kumar K. Puduvalli    800-293-5066    Jamesline@osumc.edu   
Principal Investigator: Vinay Kumar K. Puduvalli         
Mount Carmel East Hospital Recruiting
Columbus, Ohio, United States, 43213
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Riverside Methodist Hospital Recruiting
Columbus, Ohio, United States, 43214
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: Timothy D. Moore    614-488-2745    sheree@columbusccop.org   
Principal Investigator: Timothy D. Moore         
Good Samaritan Hospital - Dayton Recruiting
Dayton, Ohio, United States, 45406
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Miami Valley Hospital Recruiting
Dayton, Ohio, United States, 45409
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Dayton Physicians LLC-Samaritan North Recruiting
Dayton, Ohio, United States, 45415
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Samaritan North Health Center Recruiting
Dayton, Ohio, United States, 45415
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Armes Family Cancer Center Recruiting
Findlay, Ohio, United States, 45840
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Blanchard Valley Hospital Recruiting
Findlay, Ohio, United States, 45840
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Orion Cancer Care Recruiting
Findlay, Ohio, United States, 45840
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Wayne Hospital Recruiting
Greenville, Ohio, United States, 45331
Contact: Howard M. Gross    937-775-1350    som_dcop@wright.edu   
Principal Investigator: Howard M. Gross         
Toledo Clinic Cancer Centers-Maumee Recruiting
Maumee, Ohio, United States, 43537
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Saint Charles Hospital Suspended
Oregon, Ohio, United States, 43616
Mercy Health Perrysburg Cancer Center Recruiting
Perrysburg, Ohio, United States, 43551
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Flower Hospital Recruiting
Sylvania, Ohio, United States, 43560
Contact: Abhijit B. Saste    419-824-1842      
Principal Investigator: Abhijit B. Saste         
Mercy Saint Anne Hospital Recruiting
Toledo, Ohio, United States, 43623
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Clinic Cancer Centers-Toledo Recruiting
Toledo, Ohio, United States, 43623
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
University Pointe Recruiting
West Chester, Ohio, United States, 45069
Contact: Rekha T. Chaudhary    513-558-4553    uchealthnews@uc.edu   
Principal Investigator: Rekha T. Chaudhary         
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: James D. Battiste    530-332-3808      
Principal Investigator: James D. Battiste         
Oklahoma Cancer Specialists and Research Institute-Tulsa Recruiting
Tulsa, Oklahoma, United States, 74146
Contact: James D. Battiste    530-332-3808      
Principal Investigator: James D. Battiste         
United States, Oregon
Legacy Good Samaritan Hospital and Medical Center Recruiting
Portland, Oregon, United States, 97210
Contact: Regan M. Look    503-413-1742      
Principal Investigator: Regan M. Look         
Providence Portland Medical Center Recruiting
Portland, Oregon, United States, 97213
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Providence Saint Vincent Medical Center Recruiting
Portland, Oregon, United States, 97225
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Kaiser Permanente Northwest Recruiting
Portland, Oregon, United States, 97227
Contact: Abdul H. Mansoor    503-335-2400      
Principal Investigator: Abdul H. Mansoor         
United States, Pennsylvania
Abington Memorial Hospital Recruiting
Abington, Pennsylvania, United States, 19001
Contact: Willard G. Andrews    215-481-2402      
Principal Investigator: Willard G. Andrews         
Lehigh Valley Hospital-Cedar Crest Recruiting
Allentown, Pennsylvania, United States, 18103
Contact: Tareq Al Baghdadi    208-367-7954      
Principal Investigator: Tareq Al Baghdadi         
Geisinger Medical Center Recruiting
Danville, Pennsylvania, United States, 17822
Contact: Na Tosha N. Gatson    570-271-5251      
Principal Investigator: Na Tosha N. Gatson         
UPMC Pinnacle Cancer Center/Community Osteopathic Campus Suspended
Harrisburg, Pennsylvania, United States, 17109
Lancaster General Hospital Suspended
Lancaster, Pennsylvania, United States, 17604
Allegheny General Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15212
Contact: Larisa Greenberg    877-284-2000      
Principal Investigator: Larisa Greenberg         
University of Pittsburgh Cancer Institute (UPCI) Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Jan Drappatz    412-647-2811      
Principal Investigator: Jan Drappatz         
Guthrie Medical Group PC-Robert Packer Hospital Recruiting
Sayre, Pennsylvania, United States, 18840
Contact: Philip A. Lowry    800-836-0388      
Principal Investigator: Philip A. Lowry         
Geisinger Wyoming Valley/Henry Cancer Center Recruiting
Wilkes-Barre, Pennsylvania, United States, 18711
Contact: Na Tosha N. Gatson    570-271-5251      
Principal Investigator: Na Tosha N. Gatson         
UPMC Susquehanna Recruiting
Williamsport, Pennsylvania, United States, 17701
Contact: Warren L. Robinson    412-647-8073      
Principal Investigator: Warren L. Robinson         
Lankenau Medical Center Recruiting
Wynnewood, Pennsylvania, United States, 19096
Contact: Albert S. DeNittis    484-476-2649    ewend@mlhs.org   
Principal Investigator: Albert S. DeNittis         
United States, Rhode Island
Rhode Island Hospital Recruiting
Providence, Rhode Island, United States, 02903
Contact: Heinrich Elinzano    401-444-1488      
Principal Investigator: Heinrich Elinzano         
United States, South Carolina
Roper Hospital Recruiting
Charleston, South Carolina, United States, 29401
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Charleston Hematology Oncology Associates-Roper Recruiting
Charleston, South Carolina, United States, 29403
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Lowcountry Hematology Oncology PA-North Charleston Recruiting
Charleston, South Carolina, United States, 29406
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Bon Secours Saint Francis Hospital Recruiting
Charleston, South Carolina, United States, 29414
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Charleston Hematology Oncology Associates PA-St. Francis Recruiting
Charleston, South Carolina, United States, 29414
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Lowcountry Hematology Oncology PA-West Ashley Recruiting
Charleston, South Carolina, United States, 29414
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Medical University of South Carolina Recruiting
Charleston, South Carolina, United States, 29425
Contact: Scott M. Lindhorst    843-792-9321      
Principal Investigator: Scott M. Lindhorst         
Greenville Health System Cancer Institute-Easley Recruiting
Easley, South Carolina, United States, 29640
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Gibbs Cancer Center-Gaffney Recruiting
Gaffney, South Carolina, United States, 29341
Contact: Abderrahim Khomani    800-486-5941      
Principal Investigator: Abderrahim Khomani         
Saint Francis Hospital Recruiting
Greenville, South Carolina, United States, 29601
Contact: Jeremy M. Kilburn    800-486-5941      
Principal Investigator: Jeremy M. Kilburn         
Greenville Health System Cancer Institute-Andrews Suspended
Greenville, South Carolina, United States, 29605
Greenville Health System Cancer Institute-Butternut Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Faris Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Greenville Memorial Hospital Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Saint Francis Cancer Center Recruiting
Greenville, South Carolina, United States, 29607
Contact: Jeremy M. Kilburn    800-486-5941      
Principal Investigator: Jeremy M. Kilburn         
Greenville Health System Cancer Institute-Eastside Recruiting
Greenville, South Carolina, United States, 29615
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Greer Recruiting
Greer, South Carolina, United States, 29650
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Gibbs Cancer Center-Pelham Recruiting
Greer, South Carolina, United States, 29651
Contact: Abderrahim Khomani    800-486-5941      
Principal Investigator: Abderrahim Khomani         
Lowcountry Hematology Oncology PA-Mount Pleasant Recruiting
Mount Pleasant, South Carolina, United States, 29464
Contact: Steven A. Akman    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: Steven A. Akman         
Greenville Health System Cancer Institute-Seneca Recruiting
Seneca, South Carolina, United States, 29672
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
Spartanburg Medical Center Recruiting
Spartanburg, South Carolina, United States, 29303
Contact: Abderrahim Khomani    800-486-5941      
Principal Investigator: Abderrahim Khomani         
Greenville Health System Cancer Institute-Spartanburg Recruiting
Spartanburg, South Carolina, United States, 29307
Contact: Jeffrey K. Giguere    864-679-3966      
Principal Investigator: Jeffrey K. Giguere         
United States, South Dakota
Avera Cancer Institute-Aberdeen Recruiting
Aberdeen, South Dakota, United States, 57401
Contact: Amy K. Krie    888-634-7268    oncregulatory@avera.org   
Principal Investigator: Amy K. Krie         
Rapid City Regional Hospital Recruiting
Rapid City, South Dakota, United States, 57701
Contact: Michael O. Robinson    605-716-3982    research@rcrh.org   
Principal Investigator: Michael O. Robinson         
Sanford Cancer Center-Oncology Clinic Recruiting
Sioux Falls, South Dakota, United States, 57104
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
Avera Cancer Institute Recruiting
Sioux Falls, South Dakota, United States, 57105
Contact: Amy K. Krie    888-634-7268    oncregulatory@avera.org   
Principal Investigator: Amy K. Krie         
Sanford USD Medical Center - Sioux Falls Recruiting
Sioux Falls, South Dakota, United States, 57117-5134
Contact: Preston D. Steen    712-252-0088      
Principal Investigator: Preston D. Steen         
United States, Tennessee
Wellmont Holston Valley Hospital and Medical Center Recruiting
Kingsport, Tennessee, United States, 37660
Contact: Asheesh Shipstone    423-224-5593      
Principal Investigator: Asheesh Shipstone         
University of Tennessee - Knoxville Suspended
Knoxville, Tennessee, United States, 37920
Vanderbilt University/Ingram Cancer Center Recruiting
Nashville, Tennessee, United States, 37232
Contact: Paul L. Moots    800-811-8480      
Principal Investigator: Paul L. Moots         
United States, Texas
UT Southwestern/Simmons Cancer Center-Dallas Recruiting
Dallas, Texas, United States, 75390
Contact: Edward Pan    214-590-5582      
Principal Investigator: Edward Pan         
Brooke Army Medical Center Recruiting
Fort Sam Houston, Texas, United States, 78234
Contact: John S. Renshaw    210-916-4837      
Principal Investigator: John S. Renshaw         
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Jacob Mandel    713-798-1354    burton@bcm.edu   
Principal Investigator: Jacob Mandel         
Ben Taub General Hospital Recruiting
Houston, Texas, United States, 77030
Contact: Jacob Mandel    713-798-1354    burton@bcm.edu   
Principal Investigator: Jacob Mandel         
M D Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Shiao-Pei S. Weathers    713-792-3245      
Principal Investigator: Shiao-Pei S. Weathers         
Memorial Hermann Texas Medical Center Suspended
Houston, Texas, United States, 77030
United States, Utah
Huntsman Cancer Institute/University of Utah Suspended
Salt Lake City, Utah, United States, 84112
United States, Vermont
University of Vermont College of Medicine Recruiting
Burlington, Vermont, United States, 05405
Contact: Alissa A. Thomas    802-656-4101      
Principal Investigator: Alissa A. Thomas         
United States, Virginia
University of Virginia Cancer Center Recruiting
Charlottesville, Virginia, United States, 22908
Contact: David Schiff    434-243-6322    JME3D@hscmail.mcc.virginia.edu   
Principal Investigator: David Schiff         
Danville Hematology Oncology Recruiting
Danville, Virginia, United States, 24541
Contact: Qiwei W. Gai    434-799-3753      
Principal Investigator: Qiwei W. Gai         
Inova Fairfax Hospital Recruiting
Falls Church, Virginia, United States, 22042
Contact: James W. Leiphart    703-208-6650    Stephanie.VanBebber@inova.org   
Principal Investigator: James W. Leiphart         
United States, Washington
MultiCare Auburn Medical Center Recruiting
Auburn, Washington, United States, 98001
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
PeaceHealth Saint Joseph Medical Center Recruiting
Bellingham, Washington, United States, 98225
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
Highline Medical Center-Main Campus Recruiting
Burien, Washington, United States, 98166
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
MultiCare Gig Harbor Medical Park Recruiting
Gig Harbor, Washington, United States, 98335
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
MultiCare Good Samaritan Hospital Recruiting
Puyallup, Washington, United States, 98372
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
Virginia Mason Medical Center Recruiting
Seattle, Washington, United States, 98101
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
Franciscan Research Center-Northwest Medical Plaza Recruiting
Tacoma, Washington, United States, 98405
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
MultiCare Tacoma General Hospital Recruiting
Tacoma, Washington, United States, 98405
Contact: John A. Keech    907-458-5380      
Principal Investigator: John A. Keech         
Northwest Medical Specialties PLLC Recruiting
Tacoma, Washington, United States, 98405
Contact: Mehmet S. Copur    501-622-2100      
Principal Investigator: Mehmet S. Copur         
PeaceHealth Southwest Medical Center Recruiting
Vancouver, Washington, United States, 98664
Contact: Alison K. Conlin    907-212-6871    AKPAMC.OncologyResearchSupport@providence.org   
Principal Investigator: Alison K. Conlin         
United States, West Virginia
West Virginia University Healthcare Recruiting
Morgantown, West Virginia, United States, 26506
Contact: Aaron P. Provenzano    304-293-7374    cancertrialsinfo@hsc.wvu.edu   
Principal Investigator: Aaron P. Provenzano         
United States, Wisconsin
Aurora Cancer Care-Southern Lakes VLCC Recruiting
Burlington, Wisconsin, United States, 53105
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Marshfield Clinic Cancer Center at Sacred Heart Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Sacred Heart Hospital Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Aurora Health Center-Fond du Lac Recruiting
Fond Du Lac, Wisconsin, United States, 54937
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora Health Care Germantown Health Center Recruiting
Germantown, Wisconsin, United States, 53022
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora Cancer Care-Grafton Recruiting
Grafton, Wisconsin, United States, 53024
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Green Bay Oncology at Saint Vincent Hospital Suspended
Green Bay, Wisconsin, United States, 54301-3526
Saint Vincent Hospital Cancer Center Green Bay Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Anthony J. Jaslowski    920-433-8889    Christy.Gilchrist@hshs.org   
Principal Investigator: Anthony J. Jaslowski         
Green Bay Oncology Limited at Saint Mary's Hospital Suspended
Green Bay, Wisconsin, United States, 54303
Saint Vincent Hospital Cancer Center at Saint Mary's Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Anthony J. Jaslowski    920-433-8889    Christy.Gilchrist@hshs.org   
Principal Investigator: Anthony J. Jaslowski         
Aurora BayCare Medical Center Recruiting
Green Bay, Wisconsin, United States, 54311
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Mercy Health System Recruiting
Janesville, Wisconsin, United States, 53547
Contact: Emily G. Robinson    800-928-1103      
Principal Investigator: Emily G. Robinson         
Gundersen Lutheran Medical Center Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Michael O. Ojelabi    608-775-2385    cancerctr@gundersenhealth.org   
Principal Investigator: Michael O. Ojelabi         
University of Wisconsin Hospital and Clinics Recruiting
Madison, Wisconsin, United States, 53792
Contact: H. I. Robins    800-622-8922      
Principal Investigator: H. I. Robins         
Aurora Bay Area Medical Group-Marinette Recruiting
Marinette, Wisconsin, United States, 54143
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Vince Lombardi Cancer Clinic-Marinette Recruiting
Marinette, Wisconsin, United States, 54143
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Marshfield Clinic Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Marshfield Medical Center Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Aurora Cancer Care-Milwaukee Recruiting
Milwaukee, Wisconsin, United States, 53209
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora Saint Luke's Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53215
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Froedtert and the Medical College of Wisconsin Recruiting
Milwaukee, Wisconsin, United States, 53226
Contact: Jennifer M. Connelly    414-805-4380      
Principal Investigator: Jennifer M. Connelly         
Aurora Sinai Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53233
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Marshfield Clinic-Minocqua Center Recruiting
Minocqua, Wisconsin, United States, 54548
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
ProHealth D N Greenwald Center Suspended
Mukwonago, Wisconsin, United States, 53149
ProHealth Oconomowoc Memorial Hospital Suspended
Oconomowoc, Wisconsin, United States, 53066
Green Bay Oncology - Oconto Falls Recruiting
Oconto Falls, Wisconsin, United States, 54154
Contact: Anthony J. Jaslowski    920-433-8889    Christy.Gilchrist@hshs.org   
Principal Investigator: Anthony J. Jaslowski         
Vince Lombardi Cancer Clinic - Oshkosh Recruiting
Oshkosh, Wisconsin, United States, 54904
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora Cancer Care-Racine Recruiting
Racine, Wisconsin, United States, 53406
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Lakeview Medical Center-Marshfield Clinic Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Marshfield Clinic-Rice Lake Center Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Vince Lombardi Cancer Clinic-Sheboygan Recruiting
Sheboygan, Wisconsin, United States, 53081
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Saint Vincent Hospital Cancer Center at Sturgeon Bay Recruiting
Sturgeon Bay, Wisconsin, United States, 54235-1495
Contact: Anthony J. Jaslowski    920-433-8889    Christy.Gilchrist@hshs.org   
Principal Investigator: Anthony J. Jaslowski         
Green Bay Oncology - Sturgeon Bay Suspended
Sturgeon Bay, Wisconsin, United States, 54235
Aurora Medical Center in Summit Recruiting
Summit, Wisconsin, United States, 53066
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Vince Lombardi Cancer Clinic-Two Rivers Recruiting
Two Rivers, Wisconsin, United States, 54241
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora Cancer Care-Waukesha Suspended
Waukesha, Wisconsin, United States, 53188
ProHealth Waukesha Memorial Hospital Suspended
Waukesha, Wisconsin, United States, 53188
UW Cancer Center at ProHealth Care Suspended
Waukesha, Wisconsin, United States, 53188
Aurora Cancer Care-Milwaukee West Recruiting
Wauwatosa, Wisconsin, United States, 53226
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Aurora West Allis Medical Center Recruiting
West Allis, Wisconsin, United States, 53227
Contact: George C. Bobustuc    773-702-9171    protocols@AllianceNCTN.org   
Principal Investigator: George C. Bobustuc         
Diagnostic and Treatment Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Marshfield Clinic - Weston Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Benjamin E. Lawler    800-782-8581      
Principal Investigator: Benjamin E. Lawler         
Puerto Rico
Fundacion De Investigacion de Diego Suspended
San Juan, Puerto Rico, 00927
Sponsors and Collaborators
National Cancer Institute (NCI)
Investigators
Principal Investigator: Jann Sarkaria Alliance for Clinical Trials in Oncology
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT02152982     History of Changes
Other Study ID Numbers: NCI-2014-00616
NCI-2014-00616 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
A071102
CALGB-A071102
A071102 ( Other Identifier: Alliance for Clinical Trials in Oncology )
A071102 ( Other Identifier: CTEP )
P50CA108961 ( U.S. NIH Grant/Contract )
U10CA180821 ( U.S. NIH Grant/Contract )
U10CA031946 ( U.S. NIH Grant/Contract )
First Submitted: May 27, 2014
First Posted: June 2, 2014
Last Update Posted: November 21, 2017
Last Verified: November 2017

Additional relevant MeSH terms:
Glioblastoma
Gliosarcoma
Astrocytoma
Glioma
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Temozolomide
Dacarbazine
Veliparib
Antineoplastic Agents, Alkylating
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Poly(ADP-ribose) Polymerase Inhibitors
Enzyme Inhibitors