Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-2)

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2015 by Pfizer
Sponsor:
Information provided by (Responsible Party):
Pfizer
ClinicalTrials.gov Identifier:
NCT01975389
First received: October 21, 2013
Last updated: February 10, 2015
Last verified: February 2015
  Purpose

This study evaluates the PCSK9 inhibitor, Bococizumab (PF-04950615;RN316), compared to placebo, in reducing the occurrrence of major cardiovascular events, including cardiovascular death, myocardial infarction, stroke, and unstable angina requiring urgent revascularization in high risk subjects who are receiving background lipid lowering therapy and have cholesterol laboratory values of LDL-C >/= 100 mg/dL (2.6 mmol/L) or non-HDL-C >/=130 mg/dL (3.4 mmol/L).


Condition Intervention Phase
Cardiovascular Disease
Drug: bococizumab (PF-04950615)
Drug: Placebo
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Phase 3 Multi Center, Double Blind, Randomized, Placebo Controlled, Parallel Group Evaluation Of The Efficacy, Safety, And Tolerability Of Bococizumab (PF 0495061; RN316), In Reducing The Occurrence Of Major Cardiovascular Events In High Risk Subjects

Further study details as provided by Pfizer:

Primary Outcome Measures:
  • Cardiovascular event [ Time Frame: The time from Randomization to the first adjudicated and confirmed occurrence of a primary endpoint major cardiovascular event, up to Month 60 ] [ Designated as safety issue: No ]
    Confirmed occurrence of a major cardiovascular event, a composite endpoint which includes CV death, non fatal MI, non fatal stroke, and hospitalization for unstable angina needing urgent revascularization


Secondary Outcome Measures:
  • Hospitalization for unstable angina needing urgent revascularization [ Time Frame: The time from randomization to the first adjudicated and confirmed hospitalization for unstable angina needing urgent revascularization, assessed up to Month 60 ] [ Designated as safety issue: No ]
  • A composite endpoint of CV death, non fatal MI, and non fatal stroke [ Time Frame: The time from randomization to the first adjudicated and confirmed occurrence of a composite endpoint of CV death, non-fatal MI, and non-fatal stroke, assessed up to Month 60 ] [ Designated as safety issue: No ]
  • A composite endpoint of all-cause death, non fatal MI, and non fatal stroke, and hospitalization for unstable angina needing urgent revascularization. [ Time Frame: The time from randomization to the first adjudicated and confirmed occurrence of a composite endpoint of all-cause death, non-fatal MI, and non-fatal stroke, and hospitalization for unstable angina needing urgent revascularization, assessed up to M60 ] [ Designated as safety issue: No ]

Estimated Enrollment: 9000
Study Start Date: October 2013
Estimated Study Completion Date: March 2018
Estimated Primary Completion Date: January 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: bococizumab (PF-04950615) Drug: bococizumab (PF-04950615)
150 mg, every 2 weeks, subcutaneous. The duration of the treatment period will depend upon reaching the targeted number of adjudicated and confirmed CV outcome events, approximately 3 to 4 years after the entry of first subject into the study.
Other Name: RN316
Placebo Comparator: Placebo Drug: Placebo
Placebo comparator, every 2 weeks, subcutaneous. The duration of the treatment period will depend upon reaching the targeted number of adjudicated and confirmed CV outcome events, approximately 3 to 4 years after the entry of first subject into the study.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Must be on background lipid lowering treatment.
  • Must be at high risk of a CV event.
  • Must have an LDL C >/=100 mg/dL (2.6 mmol/L) OR non HDL C >/=130 mg/dL (3.4 mmol/L).

Exclusion Criteria:

  • An LDL C <100 mg/dL (2.6 mmol/L) or non HDL C <130 mg/dL (3.4 mmol/L).
  • Planned coronary (PCI or CABG) or other arterial revascularization.
  • New York Heart Association Class IV congestive heart failure or left ventricular ejection fraction < 25% by cardiac imaging.
  • Chronic renal insufficiency with creatinine clearance of <30 ml/min/1.73m^2 by MDRD formula or with end state renal disease on dialysis.
  • History of hemorrhagic stroke.
  • Prior exposure to PF 04950615 (RN316) or other investigational PCSK9 inhibitor.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01975389

Contacts
Contact: Pfizer CT.gov Call Center 1-800-718-1021

  Hide Study Locations
Locations
United States, Alabama
North Alabama Research Center, LLC Recruiting
Athens, Alabama, United States, 35611
Office of Ernest L. Hendrix, MD, PC Recruiting
Athens, Alabama, United States, 35611
Birmingham Heart Clinic, P.C. Not yet recruiting
Birmingham, Alabama, United States, 35235
The Kirklin Clinic Recruiting
Birmingham, Alabama, United States, 35233
University of Alabama at Birmingham (Drug Shipment) Recruiting
Birmingham, Alabama, United States, 35294
Fundamental Research, LLC Not yet recruiting
Gulf Shores, Alabama, United States, 36542
The Office of Saadat Ansari MD LLC Recruiting
Huntsville, Alabama, United States, 35801
United States, Arizona
Arrowhead Internal Medicine Recruiting
Glendale, Arizona, United States, 85308
Cochise Clinical Research Not yet recruiting
Sierra Vista, Arizona, United States, 85635
Clinical Research Advantage, Inc. (Administrative Mailing Only) Recruiting
Tempe, Arizona, United States, 85282
Southwest Heart Group Recruiting
Tucson, Arizona, United States, 85710
United States, California
Westside Medical Associates of Los Angeles Not yet recruiting
Beverly Hills, California, United States, 90211
Triwest Research Associates, LLC Recruiting
El Cajon, California, United States, 92020
Encompass Clinical Research North Coast Not yet recruiting
Encinitas, California, United States, 92024
Clinical Trials Research Recruiting
Lincoln, California, United States, 95648
Richard S. Cherlin, MD Recruiting
Los Gatos, California, United States, 95032
Facey Medical Foundation Recruiting
Mission Hills, California, United States, 91345
Saviers Medical Group Not yet recruiting
Port Hueneme, California, United States, 93041
Arch Health Partners/Clinical Research Department Not yet recruiting
Poway, California, United States, 92064
Coastal Biomedical Research, Inc. Recruiting
Santa Monica, California, United States, 90404
Encompass Clinical Research Not yet recruiting
Spring Valley, California, United States, 91978
St. Joseph's Medical Associates Recruiting
Stockton, California, United States, 95204
Westlake Medical Research Recruiting
Thousand Oaks, California, United States, 91360
Harbor UCLA Medical Center Not yet recruiting
Torrance, California, United States, 90209
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Recruiting
Torrance, California, United States, 90502
United States, Colorado
Lynn Institute of the Rockies Recruiting
Colorado Springs, Colorado, United States, 80909
Lynn Institute of the Rockies Recruiting
Colorado Springs, Colorado, United States, 80907
Lynn Institute of Denver Recruiting
Denver, Colorado, United States, 80246
United States, Connecticut
Stamford Therapeutics Consortium Recruiting
Stamford, Connecticut, United States, 6905
United States, Florida
ACRC - Cardiology Recruiting
Atlantis, Florida, United States, 33462
GulfCoast Endocrine and Diabetes Center Recruiting
Clearwater, Florida, United States, 33756
Invesclinic, LLC Recruiting
Fort Lauderdale, Florida, United States, 33308
The Office of Maxine E. Hamilton, MD, PA Recruiting
Fort Lauderdale, Florida, United States, 33316
Broward Health Medical Center Not yet recruiting
Fort Lauderdale, Florida, United States, 33316
The Office of Dr. Alan Graff, MD, PA Recruiting
Ft. Lauderale, Florida, United States, 33308
Jacksonville Center for Clinical Research Recruiting
Jacksonville, Florida, United States, 32216
River City Clinical Research Not yet recruiting
Jacksonville, Florida, United States, 32207
Meridien Research Not yet recruiting
Lakeland, Florida, United States, 33805
Research Institute of South Florida, Inc. Recruiting
Miami, Florida, United States, 33173
International Research Associates, LLC Recruiting
Miami, Florida, United States, 33183
South Florida Research Group, LLC Recruiting
Miami, Florida, United States, 33176
Pharmax Research Clinic, Inc. Recruiting
Miami, Florida, United States, 33126
Kendall South Medical Center, Inc Not yet recruiting
Miami, Florida, United States, 33185
Ocean Blue Medical Research Center, Inc. Recruiting
Miami Springs, Florida, United States, 33166
Invesclinic, LLC d/b/a SouthEast Medical Centre Recruiting
Oakland Park, Florida, United States, 33309
Omega Research Consultants, LLC Recruiting
Orlando, Florida, United States, 32806
A&R Research Group, LLC Not yet recruiting
Pembroke Pines, Florida, United States, 33024
DMI Research, Inc. Not yet recruiting
Pinellas Park, Florida, United States, 33782
The Office of Bridget Bellinger, DO Not yet recruiting
Seminole, Florida, United States, 33777
Meridien Research Not yet recruiting
St. Petersburg, Florida, United States, 33709
Concept Clinical Trials, LLC Recruiting
Tamarac, Florida, United States, 33319
Metabolic Research Institute, Inc. Recruiting
West Palm Beach, Florida, United States, 33401
United States, Georgia
Atlanta Diabetes Associates Recruiting
Atlanta, Georgia, United States, 30318
Rockdale Medical Research Associates Not yet recruiting
Conyers, Georgia, United States, 30094
Neurostudies.net, LLC Recruiting
Decatur, Georgia, United States, 30033
In-Quest Medical Research, LLC Recruiting
Norcross, Georgia, United States, 30092
United States, Idaho
Elite Clinical Trials LLLP Not yet recruiting
Blackfoot, Idaho, United States, 83221
St. Luke's Idaho Cardiology Associates Recruiting
Caldwell, Idaho, United States, 83605
United States, Illinois
Northwest Heart Clinical Research, LLC Not yet recruiting
Arlington Heights, Illinois, United States, 60005
Evanston Premier Healthcare Research, LLC Recruiting
Evanston, Illinois, United States, 60201
United States, Indiana
Investigators Research Group, LLC Recruiting
Brownsburg, Indiana, United States, 46112
Clinical Research Advantage, Inc. Recruiting
Evansville, Indiana, United States, 47714
Deaconess Clinic Downtown Recruiting
Evansville, Indiana, United States, 47713
Deaconess Clinic Mt. Pleasant Recruiting
Evansville, Indiana, United States, 47725
American Health Network of Indiana LLC Not yet recruiting
Franklin, Indiana, United States, 46131
American Health Network of Indiana LLC Not yet recruiting
Greenfield, Indiana, United States, 46140
American Health Network of Indiana, LLC Recruiting
Muncie, Indiana, United States, 47304
Buynak Clinical Research, P.C. Recruiting
Valparaiso, Indiana, United States, 46383
United States, Iowa
Clinical Research Advantage, Inc/Ridge Family Practice Not yet recruiting
Council Bluffs, Iowa, United States, 51503
West Broadway Clinic Recruiting
Council Bluffs, Iowa, United States, 51501
University of Iowa College of Public Health - Preventive Intervention Center Recruiting
Iowa City, Iowa, United States, 52242
University of Iowa, University of Hospitals and Clinics - Division Recruiting
Iowa City, Iowa, United States, 52242
United States, Kansas
Midwest Heart & Vascular Specialists, LLC Recruiting
Overland Park, Kansas, United States, 66209
Women's & Family Care D.B.A. GTC Research Recruiting
Shawnee, Kansas, United States, 66218
United States, Kentucky
The Research Group of Lexington, LLC Recruiting
Lexington, Kentucky, United States, 40503
L-MARC Recruiting
Louisville, Kentucky, United States, 40213
United States, Louisiana
Pharmacy Department (Drug Shipment address), Interim LSU Hospital Not yet recruiting
New Orleans, Louisiana, United States, 70112
Clinical Translational Research Center, Interim LSU Hospital Not yet recruiting
New Orleans, Louisiana, United States, 70112
United States, Michigan
St. Joseph Mercy Health System (Drug shipment Only) Recruiting
Ann Arbor, Michigan, United States, 48106
Quest Research Institute Recruiting
Bingham Farms, Michigan, United States, 48025
Medical Research Associates, Inc. Recruiting
Traverse City, Michigan, United States, 49684
Oakland Medical Research Center Recruiting
Troy, Michigan, United States, 48085
Troy Internal Medicine, PC Recruiting
Troy, Michigan, United States, 48098
Michigan Heart Recruiting
Ypsilanti, Michigan, United States, 48197
United States, Minnesota
Lillehei Clinical Research Unit, University of Minnesota Not yet recruiting
Minneapolis, Minnesota, United States, 55455
United States, Mississippi
Cardiology Associates Research, LLC Recruiting
Tupelo, Mississippi, United States, 38801
United States, Missouri
Saint Luke's Lipid and Diabetes Research Center Recruiting
Kansas City, Missouri, United States, 64111
United States, Montana
Montana Medical Research Inc. Recruiting
Missoula, Montana, United States, 59808
United States, Nebraska
Creighton Diabetes Center Not yet recruiting
Omaha, Nebraska, United States, 68131
United States, New Jersey
NJ Heart Recruiting
Linden, New Jersey, United States, 07036
Arysmed LLC Recruiting
Lodi, New Jersey, United States, 07644
Rutgers Biomedical and Health Sciences - Robert Wood Johnson Medical School Not yet recruiting
New Brunswick, New Jersey, United States, 08901
Westwood Cardiology Associates, P.A. Recruiting
Westwood, New Jersey, United States, 07675
United States, New York
The Endocrine Group Recruiting
Albany, New York, United States, 12206
NY Scientific Recruiting
Brooklyn, New York, United States, 11235
SJH Cardiology Associates Recruiting
Liverpool, New York, United States, 13088
Long Island Heart Associates Not yet recruiting
Mineola, New York, United States, 11501
Mid Hudson Medical Research, PLLC Recruiting
New Windsor, New York, United States, 12553
Clinical Research Development Associates, LLC Recruiting
Rosedale, New York, United States, 11422
United States, North Carolina
Sensenbrenner Primary Care Recruiting
Charlotte, North Carolina, United States, 28277
Research Institute of the Carolinas of Piedmont Healthcare, PA Recruiting
Mooresville, North Carolina, United States, 28117
Wake Forest University School of Medicine Recruiting
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Lillestol Research LLC Recruiting
Fargo, North Dakota, United States, 58103
United States, Ohio
The Lindner Center for Research and Education at The Christ Hospital Recruiting
Cincinnati, Ohio, United States, 45219
Metabolic and Atherosclerosis Research Center Recruiting
Cincinnati, Ohio, United States, 45227
Sterling Research Group, Ltd. Recruiting
Cincinnati, Ohio, United States, 45246
Medpace Clinical Pharmacology Unit Recruiting
Cincinnati, Ohio, United States, 45212
Optimed Research LTD Not yet recruiting
Columbus, Ohio, United States, 43235
SV Research LLC Recruiting
Marion, Ohio, United States, 43302
Office of Daniel G. Williams, MD Recruiting
Perrysburg, Ohio, United States, 43551
North Ohio Heart Center, Inc. Recruiting
Sandusky, Ohio, United States, 44870
United States, Oklahoma
LION Research Recruiting
Norman, Oklahoma, United States, 73069
Oklahoma Heart Hospital Not yet recruiting
Oklahoma City, Oklahoma, United States, 73120
Oklahoma Heart Hospital Physicians Not yet recruiting
Oklahoma City, Oklahoma, United States, 73120
Oklahoma Heart Hospital Research Foundation Not yet recruiting
Oklahoma City, Oklahoma, United States, 73120
United States, Oregon
Hillsboro Cardiology, P.C. Recruiting
Hillsboro, Oregon, United States, 97123
United States, Pennsylvania
Pennsylvania Research Institute Not yet recruiting
Bensalem, Pennsylvania, United States, 19020
Jefferson Cardiology Association Recruiting
Clairton, Pennsylvania, United States, 15025
Brandywine Clinical Research Recruiting
Downingtown, Pennsylvania, United States, 19335-2620
Doylestown Cardiology Associates - VIAA Recruiting
Doylestown, Pennsylvania, United States, 18901
Green and Seidner Family Practice Associates Recruiting
Lansdale, Pennsylvania, United States, 19446
Family Medical Associates Recruiting
Levittown, Pennsylvania, United States, 19056
Philadelphia Health Associates-Adult Medicine Not yet recruiting
Philadelphia, Pennsylvania, United States, 19146
Allegheny Endocrinology Associates Recruiting
Pittsburgh, Pennsylvania, United States, 15212
Preferred Primary Care Physicians Recruiting
Pittsburgh, Pennsylvania, United States, 15236
Guthrie Medical Group, PC Recruiting
Sayre, Pennsylvania, United States, 18840
United States, South Carolina
Coastal Cardiology Recruiting
Charleston, South Carolina, United States, 29407
Upstate Pharmaceutical Research Recruiting
Greenville, South Carolina, United States, 29615
The Diabetes Center Recruiting
Murrells Inlet, South Carolina, United States, 29576
United States, Tennessee
New Orleans Center for Clinical Research Recruiting
Knoxville, Tennessee, United States, 37920
Volunteer Research Group Recruiting
Knoxville, Tennessee, United States, 37920
United States, Texas
Arlington Family Research Center, Inc. Recruiting
Arlington, Texas, United States, 76012
Research Institute of Dallas Recruiting
Dallas, Texas, United States, 75231
VA North Texas Health Care System - Dallas VAMC Recruiting
Dallas, Texas, United States, 75216
Baylor College of Medicine Recruiting
Houston, Texas, United States, 77030
Centex Studies, Inc. Recruiting
Houston, Texas, United States, 77062
DM Clinical Research Recruiting
Houston, Texas, United States, 77070
Northwest Houston Cardiology Recruiting
Houston, Texas, United States, 77070
Texas Center For Drug Development, Inc. Recruiting
Houston, Texas, United States, 77081
Protenium Clinical Research Not yet recruiting
Hurst, Texas, United States, 76054
Hill Country Medical Associates Recruiting
New Braunfels, Texas, United States, 78130
Med-Olam Clinical Research Recruiting
Pasadena, Texas, United States, 77504
Bandera Family Health Care Recruiting
San Antonio, Texas, United States, 78249
BFHC Research Recruiting
San Antonio, Texas, United States, 78249
Sun Research Institute Active, not recruiting
San Antonio, Texas, United States, 78215
Northwest Heart Center Recruiting
Tomball, Texas, United States, 77375
United States, Utah
Optimum Clinical Research, Inc. Recruiting
Salt Lake City, Utah, United States, 84102
United States, Virginia
Burke Internal Medicine & Research Recruiting
Burke, Virginia, United States, 22015
Clinical Research Institute of Northern Virginia Not yet recruiting
Burke, Virginia, United States, 22015
Hampton Roads Center for Clinical Research Recruiting
Suffolk, Virginia, United States, 23435
United States, Washington
Office of Daniel W. Gottlieb, MD, PS Recruiting
Burien, Washington, United States, 98166
Wenatchee Valley Hospital and Clinics Recruiting
Wenatchee, Washington, United States, 98801
Wenatchee Valley Medical Center Recruiting
Wenatchee, Washington, United States, 98801
United States, West Virginia
Exemplar Research Inc Recruiting
Fairmont, West Virginia, United States, 26554
Argentina
Hospital Italiano Regional del Sur Not yet recruiting
Bahia Blanca, Buenos Aires, Argentina, B8001HXM
Instituto de Investigaciones Clinicas Bahia Blanca Not yet recruiting
Bahia Blanca, Buenos Aires, Argentina, B8000FTD
Framingham Centro Medico Not yet recruiting
La Plata, Buenos Aires, Argentina, B1902COS
Instituto de Investigaciones Clinicas (IIC) - Mar del Plata Recruiting
Mar Del Plata, Buenos Aires, Argentina, B7600FZN
DIM Clinica Privada Not yet recruiting
Ramos Mejia, Buenos Aires, Argentina, B1704ETD
Consultorios Asociados de Endocrinologia e Investigacion Clinica Aplicada Not yet recruiting
C.a.b.a, C.a.b.a., Argentina, C1425AGC
Hospital Italiano Garibaldi Not yet recruiting
Rosario, Santa Fe, Argentina, S2001ODA
CIPREC - Centro de Investigacion y Prevencion Cardiovascular S.A. Not yet recruiting
C.a.b.a., Argentina, C1119ACN
Centro Medico Luquez Not yet recruiting
Cordoba, Argentina, X5006IKK
Clinico Chutro SRL Not yet recruiting
Cordoba, Argentina, X5000EPU
Instituto Medico DAMIC S.R.L. Not yet recruiting
Cordoba, Argentina, X5003DCE
Instituto de Cardiologia de Corrientes "Juana Fca. Cabral" Recruiting
Corrientes, Argentina, 3400
Centro Cardiovascular Salta (TORZA V S.R.L.) Not yet recruiting
Salta, Argentina, A4400ANG
Australia, New South Wales
Central Coast Local Health District, Gosford Hospital Not yet recruiting
Gosford, New South Wales, Australia, 2250
Australia, Queensland
Holy Spirit Northside Private Hospital Limited Recruiting
Chermside, Queensland, Australia, 4032
Royal Brisbane and Women's Hospital Recruiting
Herston, Queensland, Australia, 4029
Core Research Group Pty Ltd Recruiting
Milton, Queensland, Australia, 4064
Redcliffe Hospital Not yet recruiting
Redcliffe, Queensland, Australia, 4020
Gold Coast University Hospital Not yet recruiting
Southport, Queensland, Australia, 4215
Australia, Victoria
Barwon Health-The Geelong Hospital Recruiting
Geelong, Victoria, Australia, 3220
Royal Melbourne Hospital Not yet recruiting
Parkville, Victoria, Australia, 3050
Australia, Western Australia
HPS Pharmacies Recruiting
Joondalup, Western Australia, Australia, 6027
Joondalup Cardiovascular Trials Foundation Inc. Recruiting
Joondalup, Western Australia, Australia, 6027
Belgium
AZ Sint-Jan Brugge Recruiting
Brugge, Belgium, 8000
University Hospital Brussels- Diabeteskliniek Recruiting
Brussels, Belgium, 1090
University Hospital Brussels - Centrum voor hart- en vaatziekten Recruiting
Brussels, Belgium, 1090
ZOL Campus Sint-Jan Recruiting
Genk, Belgium, 3600
Centre Hospitalier Regional de Huy Recruiting
Huy, Belgium, 4500
University Hospitals Leuven - Neurology department Recruiting
Leuven, Belgium, 3000
ZNA Jan Palfijn Not yet recruiting
Merksem, Belgium, 2170
Dr. Luc De Wolf - Private Practice Recruiting
Tienen, Belgium, 3300
Algemeen Ziekenhuis Sint-Elisabeth Not yet recruiting
Zottegem, Belgium, 9620
Canada, Alberta
LMC Diabetes & Endocrinology (Calgary) Not yet recruiting
Calgary, Alberta, Canada, T2H 2G4
Canada, British Columbia
SMH Cardiology Clinical Trials, Inc. Recruiting
Surrey, British Columbia, Canada, V3V 1N1
Canada, Ontario
LMC Diabetes & Endocrinology (Brampton) Recruiting
Brampton, Ontario, Canada, L6S 0C9
Vizel Cardiac Research - Saul Vizel Professional Medicine Corporation Recruiting
Cambridge, Ontario, Canada, N1R 7R1
LMC Diabetes & Endocrinology (Markham) Not yet recruiting
Markham, Ontario, Canada, L6B 0P9
Newmarket Cardiology Research Group Recruiting
Newmarket, Ontario, Canada, L3Y 8C3
LMC Diabetes & Endocrinology (Oakville) Recruiting
Oakville, Ontario, Canada, L6H 3P1
London Road Diagnostic Clinic and Medical Centre Not yet recruiting
Sarnia, Ontario, Canada, N7T 4X3
Sarnia Institute of Clinical Research Not yet recruiting
Sarnia, Ontario, Canada, N7T 4X3
LMC Diabetes & Endocrinology (Thornhill) Recruiting
Thornhill, Ontario, Canada, L4J 8L7
Thunder Bay Regional Research Institute Recruiting
Thunder Bay, Ontario, Canada, P7B 7C7
LMC Diabetes & Endocrinology (Bayview) Recruiting
Toronto, Ontario, Canada, M4G 3E8
Canada, Quebec
Q&T Research Chicoutimi Recruiting
Chicoutimi, Quebec, Canada, G7H 7Y8
Centre de Recherche Clinique de Laval Not yet recruiting
Laval, Quebec, Canada, H7T 2P5
Montreal Heart Institute Recruiting
Montreal, Quebec, Canada, H1T 1C8
Centre de sante et de services sociaux du Nord de Lanaudiere Not yet recruiting
St-Charles-Borromee, Quebec, Canada, J6E 6J2
C.I.C. Mauricie Inc. Recruiting
Trois-Rivieres, Quebec, Canada, G8T 7A1
Canada
Clinique des maladies lipidiques de Quebec Inc Not yet recruiting
Quebec, Canada, G1V 4M6
The Office of Karl K Misik, MD Not yet recruiting
St. John's, Canada, A1E2E2
Colombia
Hospital Pablo Tobon Uribe Not yet recruiting
Medellin, Antioquia, Colombia
Rodrigo Botero S.A.S Not yet recruiting
Medellin, Antioquia, Colombia
Centro Cientifico Asistencial Jose Luis Accini S.A.S Recruiting
Barranquilla, Atlantico, Colombia
Centro de Investigaciones y Proyectos en Neurociencias CIPNA LTDA IPS. Recruiting
Barranquilla, Atlantico, Colombia
Fundacion del Caribe para la Investigacion Biomedica - Fundacion BIOS Recruiting
Barranquilla, Atlantico, Colombia
Centro Cardiovascular Aristides Sotomayor Santa Lucia Sociedad por Acciones Simplificadas IPS Recruiting
Cartagena, Bolivar, Colombia, 130010
Centro de Diagnostico Cardiologico LTDA. Recruiting
Cartagena, Bolivar, Colombia
Hospital Universitario San Ignacio Recruiting
Bogota D.C, Cundinamarca, Colombia
Caja de Compensacion Familiar CAFAM, Sede Centro de Atencion en Salud CAFAM FLORESTA Recruiting
Bogota D.C., Cundinamarca, Colombia
Instituto Del Corazon De Bucaramanga S.A. Not yet recruiting
Bucaramanga, Santander, Colombia
Fundacion Cardiovascular de Colombia - Instituto del Corazon Floridablanca Not yet recruiting
Floridablanca, Santander, Colombia
Dexa Diab Servicios Medicos Ltda Recruiting
Bogota D.C., Colombia
Czech Republic
Fakultni nemocnice Hradec Kralove Not yet recruiting
Hradec Kralove, Czech Republic, 500 05
Kardiologie Plzen s.r.o. Not yet recruiting
Plzen, Czech Republic, 326 00
Lékárna Hurka, s.r.o. Recruiting
Praha - Stodulky, Czech Republic, 15800
Nemocnice Na Frantisku Not yet recruiting
Praha 1, Czech Republic, 110 00
Fakultni Nemocnice Kralovske Vinohrady Not yet recruiting
Praha 10, Czech Republic, 100 34
Kardiologie a interni lekarstvi Recruiting
Praha 5, Czech Republic, 158 00
Lekarsky dum Ormiga Not yet recruiting
Zlin, Czech Republic, 760 01
Denmark
Aarhus Universitetshospital Not yet recruiting
Aarhus N, Denmark, 8200
Sydvestjysk Sygehus Recruiting
Esbjerg, Denmark, 6700
Gentofte Hospital Recruiting
Hellerup, Denmark, 2900
Herlev Universitetshospital, Kardiologisk afdeling S Not yet recruiting
Herlev, Denmark, 2730
Regionshospitalet Herning Not yet recruiting
Herning, Denmark, 7400
Hvidovre Universitetshospital, Hjerte-lungemedicinsk afdeling Recruiting
Hvidovre, Denmark, 2650
Region Sjaelland Sygehus Nord, Koge Sygehus Not yet recruiting
Koge, Denmark, 4600
Odense Universitetshospital Not yet recruiting
Odense, Denmark, 5000
Regions Hospital Viborg, HEM Recruiting
Viborg, Denmark, 8800
Finland
Geri-Med Oy Not yet recruiting
Helsinki, Finland, 00180
Sedes Oy - The Office of Jaakko Tuomilehto Recruiting
Helsinki, Finland, 00920
Helsinki University Central Hospital Recruiting
Helsinki, Finland, 00290
Studycor Oy Active, not recruiting
Jyvaskyla, Finland, 40620
Laakarikeskus Aava Kerava/Aava Kerava Medical Center Recruiting
Kerava, Finland, 04200
Ite Lasaretti Recruiting
Kuopio, Finland, 70100
Oulu University Hospital Recruiting
Oulu, Finland, 90029
Terveystalo Oulu, Diapolis Recruiting
Oulu, Finland, 90100
FinnMedi Oy Recruiting
Tampere, Finland, 33520
Valkeakoski Hospital Not yet recruiting
Valkeakoski, Finland, 37600
Vantaa Research Center Recruiting
Vantaa, Finland, 01600
France
Centre Hospitalier de Cannes Not yet recruiting
Cannes Cedex, France, 06414
Centre Hospitalier Sud-Francilien - Recruiting
Corbeil-Essonnes, France, 91106
Polyclinique du Bois Not yet recruiting
Lille, France, 59000
Centre Hospitalier Saint Philibert Not yet recruiting
Lomme, France, 59462
Nouvelles Cliniques Nantaises Not yet recruiting
Nantes, France, 44200
Centre Hospitalier de PAU - Service de cardiologie Recruiting
Pau, France, 64046
CHU Poitiers Not yet recruiting
Poitiers, France, 86021
Cabinet du Dr Taminau Denis Not yet recruiting
Rosiers d'Egletons, France, 19300
CHU de Toulouse-Hopital Rangueil Not yet recruiting
Toulouse cedex 09, France, 31059
Hopital Guy Chatiliez Recruiting
Tourcoing, France, 59200
Centre Hospitalier (CH) de Valenciennes Recruiting
Valenciennes, France, 59300
Germany
Institut fuer Klinische Forschung und Entwicklung(IKFE) Berlin GmbH Recruiting
Berlin, Germany, 10115
Klinische Forschung Berlin - Buch GmbH Recruiting
Berlin, Germany, 13125
Klinische Forschung Berlin-Buch GmbH Recruiting
Berlin, Germany, 13125
Synexus Berlin Clinical Research Centre Recruiting
Berlin, Germany, 12627
Kliniken Bielefeld - Abteilung für Klinische Forschung Recruiting
Bielefeld, Germany, 33604
Städtische Kliniken Bielefeld gem. GmbH Recruiting
Bielefeld, Germany, 33604
Synexus Bochum Clinical Research Centre Recruiting
Bochum, Germany, 44787
Cardiac Research GmbH Recruiting
Dortmund, Germany, 44227
GWT-TUD GmbH, Studienzentrum Professor Hanefeld Recruiting
Dresden, Germany, 01307
Synexus Clinical Research GmbH Recruiting
Frankfurt, Germany, 60596
Klinik und Poliklinik fuer Innere Medizin B - Kardiologie, Angiologie, Pulmologie, Recruiting
Greifswald, Germany, 17475
Klinische Forschung Hannover - Mitte GmbH Recruiting
Hannover, Germany, 30159
Universitaetsklinikum Jena Recruiting
Jena, Germany, 07747
Synexus Leipzig Clinical Research Centre Recruiting
Leipzig, Germany, 04103
Staedtisches Klinikum Muenchen GmbH Recruiting
Munich, Germany, 81737
Klinische Forschung Schwerin GmbH Recruiting
Schwerin, Germany, 19055
Kardiologische Praxis Recruiting
Wermsdorf, Germany, 04779
Hungary
DRC Kft. Recruiting
Balatonfured, Hungary, 8230
Synexus Magyarorszag Kft. - Synexus Hungary Clinical Research Centre Recruiting
Budapest, Hungary, 1036
Egyesitett Szent Istvan es Szent Laszlo Korhaz-Rendelointezet Recruiting
Budapest, Hungary, 1097
Semmelweis Egyetem, II. Belgyogyaszati Klinika Recruiting
Budapest, Hungary, 1088
Debreceni Egyetem Klinikai Kozpont Not yet recruiting
Debrecen, Hungary, 4032
Medifarma-98 Kft. Recruiting
Nyiregyhaza, Hungary, 4400
Zala Megyei Korhaz, Diabetologiai Szakrendeles Recruiting
Zalaegerszeg, Hungary, 8900
Zala Megyei Korhaz, Pozva Recruiting
Zalaegerszeg-Pozva, Hungary, 8900
Israel
Ben Yair Community Clinic - Clalit Health Services Not yet recruiting
Beer Sheva, Israel, 84350
Gefen - Cardiac Health Center Recruiting
Givatayim, Israel, 53583
Rambam Medical Center Recruiting
Haifa, Israel, 31096
Cardiovascular Clinical Research Institute Recruiting
Haifa, Israel, 34362
Edith Wolfson Medical Center Recruiting
Holon, Israel, 58100
Edith Wolfson Medical Center Not yet recruiting
Holon, Israel, 58100
Hadassah Ein Kerem Medical Center Not yet recruiting
Jerusalem, Israel, 91120
Heart Institute, Bikur Cholim Campus, Shaare Zedek Medical Center Not yet recruiting
Jerusalem, Israel, 91004
Meir Medical Center Recruiting
Kfar Saba, Israel, 44281
Meir Medical Center Recruiting
Kfar Sava, Israel, 44281
Rabin Medical Center, Beilinson Hospital Not yet recruiting
Petach Tikva, Israel, 49100
Rabin Medical Center, Beilinson Hospital Recruiting
Petach Tikva, Israel, 49100
Rabin Medical Center, Beilinson Hospital Not yet recruiting
Petah Tikva, Israel, 49100
Department of Neurology & Sagol Neuroscience Center Recruiting
Ramat Gan, Israel, 52621
Heart Institute, Kaplan Medical Center Not yet recruiting
Rehovot, Israel, 76100
Tel Aviv Sourasky Medical Centre Not yet recruiting
Tel Aviv, Israel, 64239
The Chaim Sheba Medical Center Not yet recruiting
Tel Hashomer, Israel, 5265601
The Chaim Sheba Medical Center Recruiting
Tel Hashomer, Israel, 5265601
Tel Aviv Sourasky Medical Center Not yet recruiting
Tel-Aviv, Israel, 64239
Tel Aviv Sourasky Medical Center Recruiting
Tel-Aviv, Israel, 64239
Italy
Centro Cardiologico Monzino Recruiting
Milano, MI, Italy, 20138
Azienda Ospedaliera Universitaria Policlinico "'Paolo Giaccone'' Recruiting
Palermo, PA, Italy, 90127
Dip. Medicina Interna e Specialita Mediche Policlinico Umberto I Recruiting
Roma, RM, Italy, 00161
Korea, Republic of
Seoul National University Bundang Hospital Recruiting
Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707
Daegu Catholic University Medical Center Not yet recruiting
Daegu, Korea, Republic of, 705-718
Konyang University Hospital Not yet recruiting
Daejeon, Korea, Republic of, 302-718
The Catholic University of Korea, Bucheon St. Mary's Hospital Not yet recruiting
Gyeonggi-do, Korea, Republic of, 420-717
Gangnam Severance Hospital, Yonsei University Health System Not yet recruiting
Seoul, Korea, Republic of, 135-720
Hallym University Kangdong Sacred Heart Hospital Not yet recruiting
Seoul, Korea, Republic of, 134-701
Seoul Metropolitan Government - Seoul National University Boramae Medical Center Recruiting
Seoul, Korea, Republic of, 156-707
Asan Medical Center Recruiting
Seoul, Korea, Republic of, 138-736
Mexico
Consultorio de Endocrinologia y Nutriologia Recruiting
Mexico, Distrito Federal, Mexico, 07760
Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran" Not yet recruiting
Mexico, Distrito Federal, Mexico, 14000
Operadora de Hospitales Angeles S.A. de C.V. (Emergencies) Recruiting
Mexico, Distrito Federal, Mexico, 07760
Unidad de Investigacion Clinica y Atencion Medica Hepa S.C. Recruiting
Guadalajara, Jalisco, Mexico, 44670
Hospital Mexico Americano S.C. (Emergencies) Recruiting
Guadalajara, Jalisco, Mexico, 44620
Hospital Inovamed Cuernavaca (Emergencies) Recruiting
Cuernavaca, Morelos, Mexico, 62270
Instituto de Diabetes Obesidad y Nutricion, S.C. Recruiting
Cuernavaca, Morelos, Mexico, 62250
Hospital Universitario "Jose Eleuterio Gonzalez" Recruiting
Monterrey, Nuevo Leon, Mexico, 64460
Hospital Universitario "Jose Eleuterio Gonzalez" Not yet recruiting
Monterrey, Nuevo Leon, Mexico, 64460
Centro para el Desarrollo de la Medicina y de Asistencia Médica Especializada S.C. Not yet recruiting
Culiacan, Sinaloa, Mexico, 80020
Hospital Angeles Culiacan (Emergencies Only) Not yet recruiting
Culiacan, Sinaloa, Mexico, 80020
Hospital Lomas de San Luis lntemacional (Emergencies) Not yet recruiting
San Luis Potosi, Mexico, 78218
Cardioarritmias e Investigacion S.C. Not yet recruiting
San Luis Potosi, Mexico, 78200
Centro Especializado En Diabetes Y Metabolismo Recruiting
Veracruz, Mexico, 91910
Hospital D' Maria (Emergencies) Recruiting
Veracruz, Mexico, 91910
Netherlands
Academic Medical Center Recruiting
Amsterdam, NH, Netherlands, 1105 AZ
Andro Medical Research B.V. Recruiting
Breda, Netherlands, 4811 SW
Van Weel Bethesda Hospital Recruiting
Dirksland, Netherlands, 3247 BW
Albert Schweitzer Hospital Recruiting
Dordrecht, Netherlands, 3318 AT
Andro Medical Research B.V. Recruiting
Rotterdam, Netherlands, 3021
Rotterdam Research Institute Recruiting
Rotterdam, Netherlands, 3039 BD
VieCuri Medisch Centrum Recruiting
Venlo, Netherlands, 5912 BL
Poland
Wojewodzki Szpital Specjalistyczny we Wroclawiu Not yet recruiting
Wroclaw, Dolkoslaskie, Poland, 51-124
CenterMed Lublin Sp. z.o.o. Not yet recruiting
Lublin, Iubelskie, Poland, 20-044
Niepubliczny Zaklad Opieki Zdrowotnej CEREO-MED Sp. z o.o. Not yet recruiting
Lodz, Lodzkie, Poland, 92-003
Prywatny Gabinet Lekarski Dr n. med. Michal Ogorek Not yet recruiting
Piotrkow Trybunalski, Lodzkie, Poland, 97-300
CLINMEDICA OMC spolka z ograniczona odpowiedzialnoscia spolka komandytowa Not yet recruiting
Skierniewice, Lodzkie, Poland, 96-100
"LANDA"Specjalistyczne Gabinety Lekarskie Recruiting
Krakow, Malopolskie, Poland, 30-015
Szpital Specjalistyczny im. J. Dietla w Krakowie, Oddzial Kardiologii Not yet recruiting
Krakow, Malopolskie, Poland, 31-121
Medica Pro Familia Sp. z o.o. S.K.A. Not yet recruiting
Warszawa, Mazowieckie, Poland, 01-868
Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego Not yet recruiting
Warszawa, Mazowieckie, Poland, 04-628
Pomorskie Centra Kardiologiczne, Spolka z ograniczona odpowiedzialnoscia S.K.A. Not yet recruiting
Gdansk, Pomorskie, Poland, 80-126
Marek Piepiorka Gabinet Kardiologiczno - lnternistyczny Not yet recruiting
Gdynia, Pomorskie, Poland, 81-472
Centrum Medyczne "SOPMED" Sp. z o.o. Recruiting
Sopot, Pomorskie, Poland, 81-756
Indywidualna Specjalistyczna Praktyka Lekarska Malgorzata Biedrzycka Recruiting
Starogard Gdanski, Pomorskie, Poland, 83-200
Medica Pro-Familia Sp. z o. o. SKA Oddzial Katowice Not yet recruiting
Katowice, Slaskie, Poland, 40-954
NZOZ Terapia Optima Recruiting
Katowice, Slaskie, Poland, 40-752
Prywatny Gabinet Lekarski Marianna Janion Recruiting
Kielce, Swietokrzyskie, Poland, 25-315
Niepubliczny Zaklad Opieki Zdrowotnej SOLUMED Not yet recruiting
Poznan, Wielkopolskie, Poland, 60-539
Medica Pro Familia Sp. z o.o. Spolka Komandytowo Akcyjna, Oddzial w Gdyni Recruiting
Gdynia, Poland, 81-338
Synexus Polska Sp. z o.o. Oddzial w Gdyni Recruiting
Gdynia, Poland, 81-384
SYNEXUS Polska Sp. z o.o. Oddzial w Katowicach Recruiting
Katowice, Poland, 40-040
Krakowski Szpital Specjalistyczny im. Jana Pawla II, Oddzial Szybkiej Diagnostyki Not yet recruiting
Krakow, Poland, 31-202
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Not yet recruiting
Krakow, Poland, 31-501
Centrum Terapii Wspolczesnej Not yet recruiting
Lodz, Poland, 90-242
Medicus w Opolu Sp z o. o. Recruiting
Opole, Poland, 45-706
Specjalistyczny Osrodek Leczniczo-Badawczy Zbigniew Zegota Not yet recruiting
Ostroda, Poland, 14-100
Synexus Polska Sp. z o.o. Oddzial w Poznaniu Recruiting
Poznan, Poland, 60-702
NZOZ Przychodnia Specjalistyczna Andrzej wittek Henryk Rudzki S.C. Not yet recruiting
Ruda Slaska, Poland, 41-709
Synexus Polska Sp. z o.o. Oddzial w Warszawie Recruiting
Warszawa, Poland, 01-192
Centrum Medyczne AMED Not yet recruiting
Warszawa, Poland, 01-518
Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Recruiting
Warszawa, Poland, 04-628
Synexus Polska Sp. z o.o. Oddzial we Wroclawiu Recruiting
Wroclaw, Poland, 50-088
Samodzielny Publiczny Szpital Wojewodzki im. Papieza Jana Pawla II, Oddzial Nefrologii Not yet recruiting
Zamosc, Poland, 22-400
Puerto Rico
Cardiometabolic Research Center, Inc. Not yet recruiting
Ponce, Puerto Rico, 00717
Endocrine Lipid Diabetes Research Institute Not yet recruiting
Ponce, Puerto Rico, 00717
Miguel Sosa-Padilla, MD-Private Practice Recruiting
San Juan, Puerto Rico, 00926-2832
Centro de Diabetes para Puerto Rico Recruiting
San Juan, Puerto Rico, 00935
Altamira Family Medicine And Research Institute Not yet recruiting
San Juan, Puerto Rico, 00920
Romania
Centrul Medical Sf. Stefan Recruiting
Timisoara, jud. Timis, Romania, 300125
Centrul Medical Dr. Negrisanu SRL, Diabet Zaharat Nutritie si Boli Metabolice Recruiting
Timisoara, judet Timis, Romania, 300456
Spitalul Clinic Colentina, Departament Cardiologie Not yet recruiting
Bucuresti, Romania, 020125
Spitalul Clinic Judetean de Urgenta Cluj-Napoca, Diabet Zaharat, Nutritie si Boli Metabolice Not yet recruiting
Cluj, Romania, 400006
Cardio Med SRL, Cardiologie Not yet recruiting
Tg. Mures, Romania, 540124
Russian Federation
Saint Petersburg State Budgetary Institution of Healthcare Not yet recruiting
St. Petersburg, Sestroretsk, Russian Federation, 197706
FSBI "Research institute of complex problems of cardio-vascular diseases" of Siberian Department of Not yet recruiting
Kemerovo, Russian Federation, 650002
Municipal Budgetary Healthcare Institution Not yet recruiting
Kemerovo, Russian Federation, 650000
Regional Budgetary Healthcare Institution "Kursk City Clinical Emergency Hospital" of Not yet recruiting
Kursk, Russian Federation, 305035
Moscow State Healthcare Institution "City clinical hospital n.a. S.P.Botkin" Not yet recruiting
Moscow, Russian Federation, 125284
State Budget Institution of Healthcare (SBIH) of Moscow "City Clinical Hospital Not yet recruiting
Moscow, Russian Federation, 127644
State Budgetary Institution of Healthcare of Novosibirsk region Recruiting
Novosibirsk, Russian Federation, 630102
Municipal Budgetary Institution of Healthcare of Novosibirsk Not yet recruiting
Novosibirsk, Russian Federation, 630102
Limited Liability Company "Reavita" Recruiting
Saint Petersburg, Russian Federation, 194354
LLC "Institution of medical studies" Recruiting
Saint Petersburg, Russian Federation, 196084
Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #26" Not yet recruiting
Saint-Petersburg, Russian Federation, 196247
SBEI of HPE "First Pavlov State Medical University of St. Petersburg" of the MoH of the RF Not yet recruiting
Saint-Petersburg, Russian Federation, 197022
MHI "City Clinical Hospital #12" of the Healthcare Committee of the Administration of Municipal Recruiting
Saratov, Russian Federation, 410039
State Budget Educational Institution of Higher Professional Education Not yet recruiting
Smolensk, Russian Federation, 214019
State Budgetary Educational Institution of Highest Professional education Recruiting
Tomsk, Russian Federation, 634050
"Tyumen Cardiology Center" Affiliate of the FSBSI "Scientific and Research Institution of Cardiology Recruiting
Tyumen, Russian Federation, 625026
State Autonomous Institution of Healthcare of Tyumen region "Scientific-Practical Medical Center" Not yet recruiting
Tyumen, Russian Federation, 625000
State Budgetary Healthcare Institution of Yaroslavl Region "Clinical Hospital No. 10" Not yet recruiting
Yaroslavl, Russian Federation, 150023
State Institution of Healthcare of Yaroslavl Region Clinical Hospital #2 Recruiting
Yaroslavl, Russian Federation, 150010
SBEI of HPE "Yaroslavl State Medical Academy" of the Ministry of Healthcare and Social Development Recruiting
Yaroslavl, Russian Federation, 150000
Slovakia
Alian s.r.o., kardiologicka ambulancia Recruiting
Bardejov, Slovakia, 08501
Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto Not yet recruiting
Bratislava, Slovakia, 81369
Kardiovaskularne Centrum S.R.O. Recruiting
Bratislava, Slovakia, 83101
Metabolicke Centrum MUDr. Katariny Raslovej, S.R.O. Recruiting
Bratislava, Slovakia, 83101
Narodny ustav srdcovych a cievnych chorob, a.s. Recruiting
Bratislava, Slovakia, 83348
Univerzitna nemocnica Bmtislava, Nemocnica Stare Mesto Not yet recruiting
Bratislava, Slovakia, 81369
JM-Interna s.r.o., interna ambulancia Recruiting
Dolny Kubin, Slovakia, 02601
Cardio D&R spol.s.r.o., kardiologicka ambulancia Not yet recruiting
Kosice, Slovakia, 04022
Kardiocentrum Nitra, s.r.o. Not yet recruiting
Nitra, Slovakia, 949 01
Fakultna nemocnica s poliklinikou Nove Zamky, I. interna klinika Recruiting
Nove Zamky, Slovakia, 940 34
Medivasa S.R.O., Diabetologicka Ambulancia Recruiting
Zilina, Slovakia, 01001
South Africa
Iatros International Recruiting
Bloemfontein, Free State, South Africa, 9301
Midrand Medical Centre Not yet recruiting
Halfway House, Gauteng, South Africa, 1685
I Engelbrecht Research (Pty) Ltd Not yet recruiting
Lyttelton, Gauteng, South Africa, 0157
Medipark Centre for Clinical Research Not yet recruiting
Pretoria, Gauteng, South Africa, 0158
Synexus SA Watermeyer Clinical Research Centre Recruiting
Pretoria, Gauteng, South Africa, 0184
Roodepoort Medicross Clinical Research Centre Recruiting
Roodepoort, Gauteng, South Africa, 1724
Medi-Clinic Heart Hospital Not yet recruiting
Sunnyside, Gauteng, South Africa, 0083
Clinical Projects Research SA (Pty) Ltd Recruiting
Worcester, Western Cape, South Africa, 6850
Global Clinical Trials (Pty) Ltd. Not yet recruiting
Arcadia, Pretoria, South Africa, 0001
Helderberg Clinical Trials Centre Not yet recruiting
Cape Town, South Africa, 7130
Unitas Hospital Not yet recruiting
Centurion, South Africa, 157
Centre for Diabetes and Endocrinology Not yet recruiting
Houghton, South Africa, 2198
Nash Ranjith Research Centre Not yet recruiting
Merebank, Durban, South Africa, 4052
Paarl Research Centre Recruiting
Paarl, South Africa, 7646
TREAD Research cc Recruiting
Parow, South Africa, 7500
Helderberg Research Institute Not yet recruiting
Somerset West, South Africa, 7130
Drs Joynt Venter & Associates Recruiting
Witbank (eMalahleni), South Africa, 1035
Spain
Hospital Regional Universitario de Malaga Not yet recruiting
Malaga, Andalucia, Spain, 29010
Institut Catala De La Salut - Hospital Universitari Arnau De Vilanova (Huav) Not yet recruiting
Lleida, Catalonia, Spain, 25198
Hospital Universitario San Juan de Alicante Not yet recruiting
Alicante, Comunidad Valenciana, Spain, 03550
Clinica Juaneda Not yet recruiting
Palma de Mallorca, Islas Baleares, Spain, 07014
Hospital Hospital Universitario Puerta de Hierro - Majadahonda Recruiting
Majadahonda, Madrid, Spain, 28222
Hospital Universitario Quiron Madrid Not yet recruiting
Pozuelo de Alarcon, Madrid, Spain, 28223
Hospital Universitario Cruces Not yet recruiting
Barakaldo, Pais Vasco, Spain, 48903
Hospital General De Requena Recruiting
Requena, Valencia, Spain, 46340
Gerencia de Gestion integrada de A Coruna Recruiting
A Coruna, Spain, 15006
Hospital General Universitario de Albacete Recruiting
Albacete, Spain, 02006
Hospital General Universitario de Alicante; Servicio Cardiologia Recruiting
Alicante, Spain, 03010
Hospital Virgen del Mar Not yet recruiting
Almeria, Spain, 04120
Centro Medico Teknon Not yet recruiting
Barcelona, Spain, 08022
Centro Medico Teknon ( pharmacy) Not yet recruiting
Barcelona, Spain, 08022
EAP Sardenya Recruiting
Barcelona, Spain, 08025
Hospital de la Santa Creu i Sant Pau Recruiting
Barcelona, Spain, 08025
Parc de Salut Mar-Hospital del Mar Recruiting
Barcelona, Spain, 08003
Park de Salut Mar - Hospital del Mar Recruiting
Barcelona, Spain, 08003
Hospital Universitario Reina Sofia Recruiting
Cordoba, Spain, 14004
Hospital Universitario Virgen De Las Nieves Not yet recruiting
Granada, Spain, 18014
Hospital Universitario San Cecilio Recruiting
Granada, Spain, 18012
Hospital General Universitario Gregorio Maranon Recruiting
Madrid, Spain, 28007
Hospital Universitario La Paz; Unidad Metabolico-Vascular Not yet recruiting
Madrid, Spain, 28046
Hospital Universitario Ramon y Cajal Recruiting
Madrid, Spain, 28034
Hospital Universitario Virgen de la Victoria. CE San Jose Obrero Not yet recruiting
Malaga, Spain, 29006
Hospital Universitario Virgen del Rocio Recruiting
Sevilla, Spain, 41013
Hospital Universitario Virgen de Macarena Recruiting
Sevilla, Spain, 41009
Hospital Universitario Virgen Macarena Recruiting
Sevilla, Spain, 41009
Hospital Universitari de Taragona Joan XXIII Not yet recruiting
Tarragona, Spain, 43007
Sweden
Hjartkliniken Not yet recruiting
Stockholm, Sweden, 188 82
Taiwan
China Medical University Hospital Recruiting
Taichung, Taiwan (R.O.C.), Taiwan, 40447
E-DA Hospital Not yet recruiting
Kaohsiung City, Taiwan, 82445
Cardinal Tien Hospital Not yet recruiting
New Taipei City, Taiwan, 23148
Clinical Trial Pharmacy, China Medical University Hospital Recruiting
Taichung, Taiwan, 40447
Clinical Trials Center, China Medical University Hospital Recruiting
Taichung, Taiwan, 40447
Department of Pharmacy, China Medical University Hospital Recruiting
Taichung, Taiwan, 40447
National Cheng Kung University Hospital Recruiting
Tainan, Taiwan, 704
Clinical Trial Pharmcy Recruiting
Taipei, Taiwan, 11217
General Clinical Research Center Recruiting
Taipei, Taiwan, 11217
MacKay Memorial Hospital Recruiting
Taipei, Taiwan, 10449
Taipei Veterans General Hospital Recruiting
Taipei, Taiwan, 11217
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 10002
United Kingdom
Synexus Thames Valley Clinical Research Centre Recruiting
Reading, Berkshire, United Kingdom, RG2 0TG
Peterborough and Stamford Hospitals NHS Foundation Trust Recruiting
Peterborough, Cambridgeshire, United Kingdom, PE3 9GZ
Queens Hospital Recruiting
Romford, Essex, United Kingdom, RM7 0AG
Royal Oldham Hospital Recruiting
Oldham, Greater Manchester, United Kingdom, OL1 2JH
Lister Hospital Not yet recruiting
Stevenage, Hertfordshire, United Kingdom, SG1 4AB
Queen Elizabeth II Hospital, Howlands Recruiting
Welwyn Garden City, Hertfordshire, United Kingdom, AL7 4HQ
Medway Maritime Hospital Not yet recruiting
Gillingham, Kent, United Kingdom, ME7 5NY
Layton Medical Centre Recruiting
Blackpool, Lancashire, United Kingdom, FY3 7EN
Synexus Lancashire Clinical Research Centre Recruiting
Chorley, Lancashire, United Kingdom, PR7 7NA
Synexus Merseyside Clinical Research Centre Recruiting
Liverpool, Merseyside, United Kingdom, L22 0LG
Synexus North East Clinical Research Centre Recruiting
Hexham, Northumberland, United Kingdom, NE46 1QJ
City Hospital Not yet recruiting
Birmingham, West Midlands, United Kingdom, B18 7QH
Synexus Midlands Clinical Research Centre Recruiting
Birmingham, West Midlands, United Kingdom, B15 2SQ
Synexus Wales Clinical Research Centre Recruiting
Cardiff, United Kingdom, CF14 5GJ
Little Common Surgery Recruiting
East Sussex, United Kingdom, TN39 4SP
BHF Glasgow Cardiovascular Research Centre Recruiting
Glasgow, United Kingdom, G12 8TA
Glasgow Clinical Research Facility Recruiting
Glasgow, United Kingdom, G11 6NT
Synexus Scotland Clinical Research Centre Not yet recruiting
Glasgow, United Kingdom, G20 0SP
Western Infirmary (Pharmacy) Recruiting
Glasgow, United Kingdom, G11 6NT
St Bartholomew's Hospital - Barts Health NHS Trust Recruiting
London, United Kingdom, EC1A 7BE
Barts Health NHS Trust Recruiting
London, United Kingdom, EC1M 6BQ
Clinical Trials Dispensary, 4th Floor Inpatient Pharmacy, Royal Manchester Children's Hospital Recruiting
Manchester, United Kingdom, M13 9WL
Synexus Manchester Clinical Research Centre Recruiting
Manchester, United Kingdom, M15 6SX
The Old St. Mary's Hospital (Central Manchester University Hospital NHS Foundation Trust) Recruiting
Manchester, United Kingdom, M13 9WL
The Avenue Surgery Recruiting
Wiltshire, United Kingdom, BA12 9AA
Sponsors and Collaborators
Pfizer
Investigators
Study Director: Pfizer CT.gov Call Center Pfizer
  More Information

Additional Information:
No publications provided

Responsible Party: Pfizer
ClinicalTrials.gov Identifier: NCT01975389     History of Changes
Other Study ID Numbers: B1481038, CV OUTCOMES 2, 2013-002795-41
Study First Received: October 21, 2013
Last Updated: February 10, 2015
Health Authority: United States: Food and Drug Administration

Keywords provided by Pfizer:
myocardial infarction
stroke
hyperlipidemia

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on February 27, 2015