Try our beta test site

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction (PARAGON-HF)

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2017 by Novartis
Sponsor:
Information provided by (Responsible Party):
Novartis ( Novartis Pharmaceuticals )
ClinicalTrials.gov Identifier:
NCT01920711
First received: August 8, 2013
Last updated: March 7, 2017
Last verified: March 2017
  Purpose
The purpose of this study is to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.

Condition Intervention Phase
Heart Failure With Preserved Ejection Fraction
Drug: LCZ696
Drug: Valsartan
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Participant, Investigator
Primary Purpose: Treatment
Official Title: A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients (NYHA Class II-IV) With Preserved Ejection Fraction

Resource links provided by NLM:


Further study details as provided by Novartis:

Primary Outcome Measures:
  • Cumulative number of primary composite events of cardiovascular (CV) death and total (first and recurrent) HF hospitalizations. [ Time Frame: Total follow up time (up to 57 months) ]
    The primary objective of this study is to compare LCZ696 to valsartan in reducing the rate of the composite endpoint of CV death and total (first and recurrent) HF hospitalizations, in HF patients (New York Heart Association [NYHA] Class II-IV) with preserved ejection fraction (left ventricular ejection fraction [LVEF] ≥45%). The treatment arm with the lower rate of events will be deemed as having a successful response.


Secondary Outcome Measures:
  • Change in the clinical summary score from baseline to Month 8 by Kansas City Cardiomyopathy Questionnaire (KCCQ) [ Time Frame: Baseline, 8 months ]
    Evaluation of change from baseline to month 8 in KCCQ a most sensitive, specific, and responsive health-related quality of life measure for heart failure symptoms and physical limitations.

  • Change from baseline to Month 8 in New York Heart Association (NYHA) functional class [ Time Frame: Baseline, 8 months ]
    Evaluation of change from baseline to Month 8 in NYHA functional class, a well established grading scale used to classify a HF patients' level of functionality based on the signs and symptoms of HF exhibited by the patient.

  • Time to first occurance of a composite renal endpoint [ Time Frame: Total follow up time (up to 57 months) ]

    Evaluate significance of outcome modifying agents in worsening renal dysfunction.

    Composite renal endpoint defined as follows:

    • renal death, or
    • reaching ESRD, or
    • ≥50% decline in eGFR relative to baseline

  • Time to all-cause mortality [ Time Frame: Total follow up time (up to 57 months) ]
    Evaluation of the time to all cause death.


Estimated Enrollment: 4600
Actual Study Start Date: July 18, 2014
Estimated Study Completion Date: March 15, 2019
Estimated Primary Completion Date: March 15, 2019 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: LCZ696
Single Blind Run-in Period (3-8 weeks): Patients will start on Valsartan 80 mg b.i.d. for 1-2 weeks followed by LCZ696 100 mg b.i.d. for 2-4 weeks prior to randomization into the Double Blind period (up to 57 months). Patients can only be randomized from the run-in period if they meet all of the run-in safety criteria. Target dose of LCZ696 during the double blind period is 200 mg b.i.d.
Drug: LCZ696
LCZ696 50mg, 100mg and 200 mg dosage strengths will be available for dose adjustments.
Active Comparator: Valsartan
Single Blind Run-in Period (3-8 weeks): Patients will start on Valsartan 80 mg b.i.d. for 1-2 weeks followed by LCZ696 100 mg b.i.d. for 2-4 weeks prior to randomization into the Double Blind period (up to 57 months). Patients can only be randomized from the run-in period if they meet all of the run-in safety criteria. Target dose of Valsartan during the double blind period is 160 mg b.i.d.
Drug: Valsartan
Valsartan 40mg, 80mg and 160mg dosage strengths will be available for dose adjustments.

  Eligibility

Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Left ventricular ejection fraction (LVEF) ≥45% by echo during screening epoch or within 6 months prior to study entry.
  • Symptom(s) of heart failure (HF) and requiring treatment with diuretic(s) for HF at least 30 days prior to study entry.
  • Current symptom(s) of HF
  • Structural heart disease (left atrial enlargement or left ventricular hypertrophy) documented by echocardiogram.
  • Elevated NT-proBNP

Exclusion Criteria:

  • Any prior measurement of LVEF < 40%.
  • Acute coronary syndrome (including MI), cardiac surgery, other major CV surgery within 3 months , or urgent percutaneous coronary intervention within 3 months or and elective PCI within 30 days prior to entry.
  • Any clinical event within the 6 months prior to entry could have reduced the LVEF (e.g., MI, CABG), unless an echo measurement performed after the event confirms a LVEF ≥45%.
  • Current acute decompensated HF requiring therapy.
  • Patients who require treatment with 2 or more of the following: an angiotensin converting enzyme inhibitor (ACEI), an angiotensin receptor blocker (ARB) or a renin inhibitor.
  • Alternative reason for shortness of breath such as: significant pulmonary disease or severe COPD, hemoglobin (Hgb) <10 g/dl, or body mass index (BMI) > 40 kg/m2.
  • Systolic blood pressure (SBP) ≥ 180 mmHg at entry, or SBP >150 mmHg and <180 mmHg at entry unless the patient is receiving 3 or more antihypertensive drugs, or SBP < 110 mmHg at entry.

Other protocol-defined inclusion/exclusion criteria may apply.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01920711

Contacts
Contact: Novartis Pharmaceuticals 1-888-669-6682
Contact: Novartis Pharmaceuticals +41613241111

  Hide Study Locations
Locations
United States, Alabama
Novartis Investigative Site Withdrawn
Birmingham, Alabama, United States, 35209
Novartis Investigative Site Active, not recruiting
Huntsville, Alabama, United States, 35801
Novartis Investigative Site Terminated
Mobile, Alabama, United States, 36604
Novartis Investigative Site Active, not recruiting
Mobile, Alabama, United States, 36608
Novartis Investigative Site Withdrawn
Mobile, Alabama, United States, 36617-2293
Novartis Investigative Site Active, not recruiting
Muscle Shoals, Alabama, United States, 35662
United States, Arizona
Novartis Investigative Site Active, not recruiting
Tucson, Arizona, United States, 85724
United States, Arkansas
Novartis Investigative Site Active, not recruiting
Little Rock, Arkansas, United States, 72204
United States, California
Novartis Investigative Site Terminated
Anaheim, California, United States, 92801
Novartis Investigative Site Active, not recruiting
Beverly Hills, California, United States, 90211
Novartis Investigative Site Terminated
Carmichael, California, United States, 95608
Novartis Investigative Site Terminated
Fresno, California, United States, 93720
Novartis Investigative Site Terminated
La Jolla, California, United States, 92037
Novartis Investigative Site Withdrawn
Los Angeles, California, United States, 90033
Novartis Investigative Site Active, not recruiting
Los Angeles, California, United States, 90073
Novartis Investigative Site Active, not recruiting
Northridge, California, United States, 91325
Novartis Investigative Site Terminated
Oceanside, California, United States, 92056
Novartis Investigative Site Active, not recruiting
Orange, California, United States, 92868
Novartis Investigative Site Terminated
Palm Springs, California, United States, 92262
Novartis Investigative Site Withdrawn
Pomona, California, United States, 91767
Novartis Investigative Site Active, not recruiting
San Diego, California, United States, 92161
Novartis Investigative Site Active, not recruiting
Santa Ana, California, United States, 92704
United States, Colorado
Novartis Investigative Site Active, not recruiting
Denver, Colorado, United States, 80220
United States, Connecticut
Novartis Investigative Site Terminated
Hartford, Connecticut, United States, 06105-2000
Novartis Investigative Site Active, not recruiting
Hartford, Connecticut, United States, 06105
Novartis Investigative Site Active, not recruiting
New Haven, Connecticut, United States, 06520-8062
Novartis Investigative Site Active, not recruiting
Stamford, Connecticut, United States, 06905
Novartis Investigative Site Active, not recruiting
West Haven, Connecticut, United States, 06516
United States, Florida
Novartis Investigative Site Active, not recruiting
Atlantis, Florida, United States, 33462
Novartis Investigative Site Active, not recruiting
Bradenton, Florida, United States, 34209
Novartis Investigative Site Terminated
Defuniak Springs, Florida, United States, 32435
Novartis Investigative Site Active, not recruiting
Gainesville, Florida, United States, 32608
Novartis Investigative Site Withdrawn
Hallandale, Florida, United States, 33009-3770
Novartis Investigative Site Withdrawn
Jacksonville, Florida, United States, 32223
Novartis Investigative Site Terminated
Miami, Florida, United States, 33126
Novartis Investigative Site Active, not recruiting
Miami, Florida, United States, 33126
Novartis Investigative Site Active, not recruiting
Miami, Florida, United States, 33143
Novartis Investigative Site Withdrawn
Pembroke Pines, Florida, United States, 33024
Novartis Investigative Site Completed
Tallahassee, Florida, United States, 32308
United States, Georgia
Novartis Investigative Site Active, not recruiting
Atlanta, Georgia, United States, 30309
Novartis Investigative Site Active, not recruiting
Atlanta, Georgia, United States, 30310-1495
Novartis Investigative Site Terminated
Atlanta, Georgia, United States, 30342
Novartis Investigative Site Active, not recruiting
Covington, Georgia, United States, 30014
Novartis Investigative Site Withdrawn
Cumming, Georgia, United States, 30041
Novartis Investigative Site Active, not recruiting
Cumming, Georgia, United States, 30041
Novartis Investigative Site Terminated
Macon, Georgia, United States, 31201
United States, Illinois
Novartis Investigative Site Active, not recruiting
Chicago, Illinois, United States, 60611
Novartis Investigative Site Terminated
Chicago, Illinois, United States, 60612
Novartis Investigative Site Withdrawn
Chicago, Illinois, United States, 60612
Novartis Investigative Site Active, not recruiting
Chicago, Illinois, United States, 60637
Novartis Investigative Site Active, not recruiting
Evanston, Illinois, United States, 60201
Novartis Investigative Site Active, not recruiting
Hazel Crest, Illinois, United States, 60429
Novartis Investigative Site Active, not recruiting
Lombard, Illinois, United States, 60148
Novartis Investigative Site Active, not recruiting
Maywood, Illinois, United States, 60153
Novartis Investigative Site Active, not recruiting
Oakbrook Terrace, Illinois, United States, 60181
Novartis Investigative Site Active, not recruiting
Peoria, Illinois, United States, 61602
Novartis Investigative Site Active, not recruiting
Quincy, Illinois, United States, 62301
United States, Kentucky
Novartis Investigative Site Active, not recruiting
Louisville, Kentucky, United States, 40206
Novartis Investigative Site Withdrawn
Owensboro, Kentucky, United States, 42303
United States, Louisiana
Novartis Investigative Site Active, not recruiting
Baton Rouge, Louisiana, United States, 70808
Novartis Investigative Site Active, not recruiting
Hammond, Louisiana, United States, 70403
Novartis Investigative Site Active, not recruiting
Lafayette, Louisiana, United States, 70508
Novartis Investigative Site Withdrawn
New Orleans, Louisiana, United States, 70112
Novartis Investigative Site Withdrawn
New Orleans, Louisiana, United States, 70121
Novartis Investigative Site Withdrawn
Opelousas, Louisiana, United States, 70570
Novartis Investigative Site Terminated
Shreveport, Louisiana, United States, 71101
Novartis Investigative Site Withdrawn
Shreveport, Louisiana, United States, 71105
Novartis Investigative Site Active, not recruiting
Slidell, Louisiana, United States, 70458
United States, Maine
Novartis Investigative Site Active, not recruiting
Biddeford, Maine, United States, 04005
Novartis Investigative Site Active, not recruiting
Portland, Maine, United States, 04102
United States, Maryland
Novartis Investigative Site Active, not recruiting
Baltimore, Maryland, United States, 21229
Novartis Investigative Site Active, not recruiting
Baltimore, Maryland, United States, 21287
Novartis Investigative Site Active, not recruiting
Columbia, Maryland, United States, 21044
United States, Massachusetts
Novartis Investigative Site Terminated
Boston, Massachusetts, United States, 02114
Novartis Investigative Site Active, not recruiting
Boston, Massachusetts, United States, 02118
Novartis Investigative Site Terminated
Boston, Massachusetts, United States, 02215
Novartis Investigative Site Active, not recruiting
Boston, Massachusetts, United States
Novartis Investigative Site Terminated
Haverhill, Massachusetts, United States, 01830
Novartis Investigative Site Withdrawn
Natick, Massachusetts, United States, 01760
United States, Michigan
Novartis Investigative Site Active, not recruiting
Ann Arbor, Michigan, United States, 48105
Novartis Investigative Site Active, not recruiting
Detroit, Michigan, United States, 48202
Novartis Investigative Site Active, not recruiting
Grand Blanc, Michigan, United States, 48439
Novartis Investigative Site Withdrawn
Kalamazoo, Michigan, United States, 49048
Novartis Investigative Site Withdrawn
Midland, Michigan, United States, 48640
Novartis Investigative Site Active, not recruiting
Saginaw, Michigan, United States, 48601
United States, Minnesota
Novartis Investigative Site Active, not recruiting
Minneapolis, Minnesota, United States, 55417
Novartis Investigative Site Active, not recruiting
Minneapolis, Minnesota, United States, 55433
Novartis Investigative Site Active, not recruiting
Minneapolis, Minnesota, United States, 55455
Novartis Investigative Site Terminated
Robbinsdale, Minnesota, United States, 55422
Novartis Investigative Site Withdrawn
Rochester, Minnesota, United States, 55905
Novartis Investigative Site Active, not recruiting
St. Cloud, Minnesota, United States, 56303
Novartis Investigative Site Active, not recruiting
St. Paul, Minnesota, United States, 55102
United States, Mississippi
Novartis Investigative Site Active, not recruiting
Belzoni, Mississippi, United States, 39038
Novartis Investigative Site Terminated
Jackson, Mississippi, United States, 39209
Novartis Investigative Site Active, not recruiting
Jackson, Mississippi, United States, 39216
Novartis Investigative Site Withdrawn
Picayune, Mississippi, United States, 39466
United States, Missouri
Novartis Investigative Site Withdrawn
Kansas City, Missouri, United States, 64111
Novartis Investigative Site Active, not recruiting
Saint Louis, Missouri, United States, 63136
Novartis Investigative Site Active, not recruiting
St. Louis, Missouri, United States, 63110
United States, Montana
Novartis Investigative Site Active, not recruiting
Kalispell, Montana, United States, 59901 3158
United States, Nebraska
Novartis Investigative Site Terminated
Grand Island, Nebraska, United States, 68803
Novartis Investigative Site Active, not recruiting
Lincoln, Nebraska, United States, 68506
United States, New Hampshire
Novartis Investigative Site Active, not recruiting
Lebanon, New Hampshire, United States, 03756
United States, New Jersey
Novartis Investigative Site Withdrawn
Hackensack, New Jersey, United States, 07601
Novartis Investigative Site Active, not recruiting
Morristown, New Jersey, United States, 07960
Novartis Investigative Site Active, not recruiting
New Brunswick, New Jersey, United States, 08901
Novartis Investigative Site Withdrawn
Oakland, New Jersey, United States, 07436
Novartis Investigative Site Active, not recruiting
Ridgewood, New Jersey, United States, 07450
United States, New Mexico
Novartis Investigative Site Active, not recruiting
Albuquerque, New Mexico, United States, 87102
United States, New York
Novartis Investigative Site Recruiting
Bronx, New York, United States, 10467
Novartis Investigative Site Active, not recruiting
Brooklyn, New York, United States, 11215-9008
Novartis Investigative Site Active, not recruiting
Buffalo, New York, United States, 14203
Novartis Investigative Site Active, not recruiting
Buffalo, New York, United States, 14215
Novartis Investigative Site Withdrawn
Buffalo, New York, United States, 14215
Novartis Investigative Site Active, not recruiting
Flushing, New York, United States, 11355
Novartis Investigative Site Active, not recruiting
Kingston, New York, United States, 12401
Novartis Investigative Site Active, not recruiting
Northport, New York, United States, 11768
Novartis Investigative Site Active, not recruiting
Rochester, New York, United States, 14642
Novartis Investigative Site Active, not recruiting
Saratoga Springs, New York, United States, 12866
Novartis Investigative Site Withdrawn
Syracuse, New York, United States, 13202
United States, North Carolina
Novartis Investigative Site Active, not recruiting
Chapel Hill, North Carolina, United States, 27599-7075
Novartis Investigative Site Active, not recruiting
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Novartis Investigative Site Active, not recruiting
Grand Forks, North Dakota, United States, 58201
United States, Ohio
Novartis Investigative Site Active, not recruiting
Canton, Ohio, United States, 44710
Novartis Investigative Site Terminated
Cincinnati, Ohio, United States, 45219
Novartis Investigative Site Withdrawn
Dayton, Ohio, United States, 45414
Novartis Investigative Site Active, not recruiting
Marion, Ohio, United States, 43302
United States, Oklahoma
Novartis Investigative Site Terminated
Bartlesville, Oklahoma, United States, 74006
Novartis Investigative Site Active, not recruiting
Tulsa, Oklahoma, United States, 74133
United States, Oregon
Novartis Investigative Site Withdrawn
Hillsboro, Oregon, United States, 97123
Novartis Investigative Site Terminated
Portland, Oregon, United States, 97225
Novartis Investigative Site Active, not recruiting
Portland, Oregon, United States, 97225
United States, Pennsylvania
Novartis Investigative Site Terminated
Philadelphia, Pennsylvania, United States, 19102 2293
Novartis Investigative Site Active, not recruiting
Philadelphia, Pennsylvania, United States, 19107
Novartis Investigative Site Active, not recruiting
Yardley, Pennsylvania, United States, 19067
United States, Rhode Island
Novartis Investigative Site Active, not recruiting
Providence, Rhode Island, United States, 02908
Novartis Investigative Site Active, not recruiting
Warwick, Rhode Island, United States, 02886
United States, South Carolina
Novartis Investigative Site Active, not recruiting
Charleston, South Carolina, United States, 29403
United States, South Dakota
Novartis Investigative Site Active, not recruiting
Rapid City, South Dakota, United States, 57701
Novartis Investigative Site Active, not recruiting
Sioux Falls, South Dakota, United States, 57104
United States, Tennessee
Novartis Investigative Site Withdrawn
Germantown, Tennessee, United States, 38138
Novartis Investigative Site Active, not recruiting
Knoxville, Tennessee, United States, 37917
Novartis Investigative Site Withdrawn
Knoxville, Tennessee, United States, 37920
Novartis Investigative Site Active, not recruiting
Memphis, Tennessee, United States, 38104
Novartis Investigative Site Active, not recruiting
Nashville, Tennessee, United States, 37203
Novartis Investigative Site Active, not recruiting
Nashville, Tennessee, United States, 37212
United States, Texas
Novartis Investigative Site Active, not recruiting
Beaumont, Texas, United States, 77702
Novartis Investigative Site Active, not recruiting
Dallas, Texas, United States, 75204
Novartis Investigative Site Active, not recruiting
Dallas, Texas, United States, 75216
Novartis Investigative Site Active, not recruiting
Dallas, Texas, United States, 75231
Novartis Investigative Site Active, not recruiting
Dallas, Texas, United States, 75235
Novartis Investigative Site Active, not recruiting
Houston, Texas, United States, 77030
Novartis Investigative Site Active, not recruiting
Houston, Texas, United States, 77094
Novartis Investigative Site Active, not recruiting
Livingston, Texas, United States, 77351
Novartis Investigative Site Withdrawn
Marshall, Texas, United States, 75670
Novartis Investigative Site Active, not recruiting
McKinney, Texas, United States, 75069
Novartis Investigative Site Active, not recruiting
San Antonio, Texas, United States, 78234
Novartis Investigative Site Active, not recruiting
Tomball, Texas, United States, 77375
United States, Utah
Novartis Investigative Site Active, not recruiting
Salt Lake City, Utah, United States, 84124
Novartis Investigative Site Active, not recruiting
Salt Lake City, Utah, United States, 84132
United States, Vermont
Novartis Investigative Site Active, not recruiting
White River Junction, Vermont, United States, 05009
United States, Virginia
Novartis Investigative Site Completed
Richmond, Virginia, United States, 23298-0050
United States, Washington
Novartis Investigative Site Active, not recruiting
Seattle, Washington, United States, 98103
Novartis Investigative Site Active, not recruiting
Seattle, Washington, United States, 98195
Novartis Investigative Site Withdrawn
Spokane, Washington, United States, 99204
United States, Wisconsin
Novartis Investigative Site Active, not recruiting
Madison, Wisconsin, United States, 53705
Novartis Investigative Site Active, not recruiting
Madison, Wisconsin, United States, 53792-1615
Novartis Investigative Site Active, not recruiting
Milwaukee, Wisconsin, United States, 53215
Argentina
Novartis Investigative Site Active, not recruiting
Caba, Buenos Aires, Argentina, 1407
Novartis Investigative Site Active, not recruiting
Caba, Buenos Aires, Argentina, C1056ABJ
Novartis Investigative Site Active, not recruiting
Caba, Buenos Aires, Argentina, C1280AEB
Novartis Investigative Site Active, not recruiting
Quilmes, Buenos Aires, Argentina, B1878GEG
Novartis Investigative Site Active, not recruiting
Ramos Mejia, Buenos Aires, Argentina, B1704ETD
Novartis Investigative Site Active, not recruiting
Caba, Capital Federal, Argentina, C1179AAB
Novartis Investigative Site Active, not recruiting
Posadas, Misiones, Argentina, N3300AHX
Novartis Investigative Site Active, not recruiting
Ciudad de Salta, Provincia de Salta, Argentina, A4406BPF
Novartis Investigative Site Completed
Tucuman, San Miguel de Tucuman, Argentina, 4000
Novartis Investigative Site Active, not recruiting
Tucuman, San Miguel de Tucuman, Argentina, T4000ICL
Novartis Investigative Site Active, not recruiting
Rosario, Santa Fe, Argentina, 2000
Novartis Investigative Site Active, not recruiting
Rosario, Santa Fe, Argentina, 3080
Novartis Investigative Site Active, not recruiting
Rosario, Santa Fe, Argentina, S2000DSV
Novartis Investigative Site Active, not recruiting
San Miguel de Tucuman, Tucuman, Argentina, T4000IFL
Novartis Investigative Site Withdrawn
Buenos Aires, Argentina, B1602ABQ
Novartis Investigative Site Withdrawn
Buenos Aires, Argentina, C1209ABD
Novartis Investigative Site Active, not recruiting
Buenos Aires, Argentina, C1405CNF
Novartis Investigative Site Active, not recruiting
Buenos Aires, Argentina, C1425AGP
Novartis Investigative Site Active, not recruiting
Buenos Aires, Argentina, C1428DCO
Novartis Investigative Site Active, not recruiting
Caba, Argentina, C1119ACN
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5000AAX
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5000EVQ
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5003DCE
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5006CBI
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5009BSN
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5016KET
Novartis Investigative Site Active, not recruiting
Cordoba, Argentina, X5022CPU
Novartis Investigative Site Active, not recruiting
Corrientes, Argentina, W3400CBI
Novartis Investigative Site Active, not recruiting
Formosa, Argentina, P3600
Novartis Investigative Site Active, not recruiting
Salta, Argentina, 4400
Novartis Investigative Site Active, not recruiting
San Luis, Argentina, D5702JRS
Novartis Investigative Site Active, not recruiting
Santa Fe, Argentina, S3000FWO
Australia, New South Wales
Novartis Investigative Site Active, not recruiting
Gosford, New South Wales, Australia, 2250
Novartis Investigative Site Active, not recruiting
North Ryde, New South Wales, Australia, 2109
Australia, Queensland
Novartis Investigative Site Active, not recruiting
Auchenflower, Queensland, Australia, 4066
Novartis Investigative Site Active, not recruiting
Southport, Queensland, Australia, 4215
Australia, South Australia
Novartis Investigative Site Active, not recruiting
Bedford Park, South Australia, Australia, 5042
Australia, Victoria
Novartis Investigative Site Active, not recruiting
Bundoora, Victoria, Australia, 3083
Novartis Investigative Site Active, not recruiting
Epping, Victoria, Australia, 3076
Novartis Investigative Site Active, not recruiting
Geelong, Victoria, Australia, 3220
Novartis Investigative Site Recruiting
Heidelberg, Victoria, Australia, 3084
Austria
Novartis Investigative Site Active, not recruiting
Innsbruck, Tyrol, Austria, 6020
Novartis Investigative Site Active, not recruiting
Braunau, Austria, A5280
Novartis Investigative Site Active, not recruiting
Graz, Austria, 8020
Novartis Investigative Site Active, not recruiting
Graz, Austria, A-8036
Novartis Investigative Site Active, not recruiting
Großgmain, Austria, 5084
Novartis Investigative Site Active, not recruiting
Linz, Austria, 4010
Novartis Investigative Site Withdrawn
Linz, Austria, A-4010
Novartis Investigative Site Active, not recruiting
Vienna, Austria, 1130
Novartis Investigative Site Active, not recruiting
Wien, Austria, A-1090
Belgium
Novartis Investigative Site Active, not recruiting
Aalst, Belgium, 9300
Novartis Investigative Site Recruiting
Antwerpen, Belgium, 2060
Novartis Investigative Site Active, not recruiting
Brasschaat, Belgium, 2930
Novartis Investigative Site Completed
Brussel, Belgium, 1000
Novartis Investigative Site Active, not recruiting
Bruxelles, Belgium, 1200
Novartis Investigative Site Active, not recruiting
De Pinte, Belgium, 9840
Novartis Investigative Site Active, not recruiting
Genk, Belgium, 3600
Novartis Investigative Site Withdrawn
Gent, Belgium, 9000
Novartis Investigative Site Active, not recruiting
Gent, Belgium, 9000
Novartis Investigative Site Active, not recruiting
Hasselt, Belgium, 3500
Novartis Investigative Site Active, not recruiting
Huy, Belgium, 4500
Novartis Investigative Site Active, not recruiting
Kortrijk, Belgium, 8500
Novartis Investigative Site Recruiting
Leuven, Belgium, 3000
Novartis Investigative Site Active, not recruiting
Ottignies, Belgium, 1340
Brazil
Novartis Investigative Site Active, not recruiting
Goiania, GO, Brazil, 74605-020
Novartis Investigative Site Active, not recruiting
Belo Horizonte, MG, Brazil, 30150-221
Novartis Investigative Site Active, not recruiting
Uberlandia, Minas Gerais, Brazil, 38411 186
Novartis Investigative Site Active, not recruiting
Curitiba, Parana, Brazil, 80730 150
Novartis Investigative Site Active, not recruiting
Campina Grande do Sul, PR, Brazil, 83430-000
Novartis Investigative Site Active, not recruiting
Porto Alegre, RS, Brazil, 90035-003
Novartis Investigative Site Active, not recruiting
Porto Alegre, RS, Brazil, 90560-030
Novartis Investigative Site Active, not recruiting
Porto Alegre, RS, Brazil, 90880-480
Novartis Investigative Site Active, not recruiting
Porto Alegre, RS, Brazil, 91350-200
Novartis Investigative Site Active, not recruiting
Liberdade, Sao Paulo, Brazil, 01504-001
Novartis Investigative Site Active, not recruiting
Blumenau, SC, Brazil, 89010 500
Novartis Investigative Site Active, not recruiting
Campinas, SP, Brazil, 13020-431
Novartis Investigative Site Active, not recruiting
Campinas, SP, Brazil, 13060-904
Novartis Investigative Site Active, not recruiting
Ribeirao Preto, SP, Brazil, 14055-370
Novartis Investigative Site Active, not recruiting
Sao Jose do Rio Preto, SP, Brazil, 15090 000
Novartis Investigative Site Recruiting
São Paulo, SP, Brazil, 05403-000
Novartis Investigative Site Active, not recruiting
São Paulo, SP, Brazil, 08270-070
Bulgaria
Novartis Investigative Site Active, not recruiting
Burgas, Bulgaria, 8127
Novartis Investigative Site Active, not recruiting
Pazardzhik, Bulgaria, 4400
Novartis Investigative Site Active, not recruiting
Pleven, Bulgaria, 5800
Novartis Investigative Site Active, not recruiting
Plovdiv, Bulgaria, 4000
Novartis Investigative Site Active, not recruiting
Plovdiv, Bulgaria, 4002
Novartis Investigative Site Withdrawn
Russe, Bulgaria, 7002
Novartis Investigative Site Active, not recruiting
Shumen, Bulgaria, 9700
Novartis Investigative Site Active, not recruiting
Silistra, Bulgaria, 7500
Novartis Investigative Site Active, not recruiting
Sliven, Bulgaria, 8800
Novartis Investigative Site Active, not recruiting
Smolian, Bulgaria, 4700
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1000
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1202
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1233
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1309
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1407
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1527
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1606
Novartis Investigative Site Active, not recruiting
Sofia, Bulgaria, 1784
Novartis Investigative Site Active, not recruiting
Varna, Bulgaria, 9010
Novartis Investigative Site Active, not recruiting
Veliko Tarnovo, Bulgaria, 5000
Canada, Alberta
Novartis Investigative Site Active, not recruiting
Calgary, Alberta, Canada, T2N 4Z6
Canada, British Columbia
Novartis Investigative Site Active, not recruiting
Victoria, British Columbia, Canada, V8R4R2
Canada, Newfoundland and Labrador
Novartis Investigative Site Active, not recruiting
St. John, Newfoundland and Labrador, Canada, A1B 3V6
Canada, Nova Scotia
Novartis Investigative Site Active, not recruiting
Halifax, Nova Scotia, Canada, B3H 2Y9
Canada, Ontario
Novartis Investigative Site Active, not recruiting
Cambridge, Ontario, Canada, N1R 6V6
Novartis Investigative Site Active, not recruiting
Hamilton, Ontario, Canada, L8L 2X2
Novartis Investigative Site Withdrawn
Kitchener, Ontario, Canada, N2M 5N4
Novartis Investigative Site Active, not recruiting
Ottawa, Ontario, Canada, K1Y 4W7
Novartis Investigative Site Active, not recruiting
Toronto, Ontario, Canada, M5B 1W8
Novartis Investigative Site Active, not recruiting
Toronto, Ontario, Canada, M5G 1X5
Novartis Investigative Site Active, not recruiting
Toronto, Ontario, Canada, M5S 1B2
Novartis Investigative Site Active, not recruiting
Weston, Ontario, Canada, M9N 1W4
Canada, Quebec
Novartis Investigative Site Active, not recruiting
Montreal, Quebec, Canada, H1T 1C8
Novartis Investigative Site Active, not recruiting
Montreal, Quebec, Canada, H2W 1T8
Novartis Investigative Site Active, not recruiting
Montreal, Quebec, Canada, H2X 3J4
Novartis Investigative Site Active, not recruiting
Montreal, Quebec, Canada, H3G 1A4
Novartis Investigative Site Active, not recruiting
Sainte-Foy, Quebec, Canada, G1V 4G5
Novartis Investigative Site Active, not recruiting
Sherbrooke, Quebec, Canada, J1G 2E8
Novartis Investigative Site Active, not recruiting
Thetford Mines, Quebec, Canada, G6G 2V4
Novartis Investigative Site Active, not recruiting
Trois-Rivieres, Quebec, Canada, G8Z 3R9
China, Beijing
Novartis Investigative Site Active, not recruiting
Beijing, Beijing, China, 100037
Novartis Investigative Site Active, not recruiting
Beijing, Beijing, China, 100044
Novartis Investigative Site Active, not recruiting
Beijing, Beijing, China, 100730
Novartis Investigative Site Active, not recruiting
Beijing, Beijing, China, 100853
China, Chongqing
Novartis Investigative Site Active, not recruiting
Chongqing, Chongqing, China, 400010
China, Gansu
Novartis Investigative Site Active, not recruiting
Lanzhou, Gansu, China, 730030
China, Guangdong
Novartis Investigative Site Active, not recruiting
Guangzhou, Guangdong, China, 510080
Novartis Investigative Site Active, not recruiting
Guangzhou, Guangdong, China, 510515
China, Guangxi
Novartis Investigative Site Active, not recruiting
Nanning, Guangxi, China, 530021
China, Hunan
Novartis Investigative Site Active, not recruiting
Changsha, Hunan, China, 410003
China, Jiangsu
Novartis Investigative Site Active, not recruiting
Nanjing, Jiangsu, China, 210009
Novartis Investigative Site Active, not recruiting
Nanjing, Jiangsu, China, 210029
Novartis Investigative Site Active, not recruiting
Suzhou, Jiangsu, China, 215004
Novartis Investigative Site Active, not recruiting
Wuxi, Jiangsu, China
China, Jiangxi
Novartis Investigative Site Active, not recruiting
Nanchang, Jiangxi, China, 330006
China, Jilin
Novartis Investigative Site Active, not recruiting
Changchun, Jilin, China, 130022
Novartis Investigative Site Active, not recruiting
Jilin, Jilin, China, 132000
China, Liaoning
Novartis Investigative Site Active, not recruiting
Shenyang, Liaoning, China, 110003
Novartis Investigative Site Active, not recruiting
Shenyang, Liaoning, China, 110016
China, Shanghai
Novartis Investigative Site Active, not recruiting
Shanghai City, Shanghai, China, 200120
Novartis Investigative Site Active, not recruiting
Shanghai, Shanghai, China
China, Shanxi
Novartis Investigative Site Active, not recruiting
Xi'an, Shanxi, China, 710032
Novartis Investigative Site Active, not recruiting
Xian, Shanxi, China, 710061
China, Sichuan
Novartis Investigative Site Active, not recruiting
Chengdu, Sichuan, China, 610041
China, Tianjin
Novartis Investigative Site Active, not recruiting
Tianjin, Tianjin, China, 300121
China, Zhejiang
Novartis Investigative Site Active, not recruiting
Hangzhou, Zhejiang, China, 310009
Novartis Investigative Site Active, not recruiting
Hangzhou, Zhejiang, China, 310013
Novartis Investigative Site Active, not recruiting
Hangzhou, Zhejiang, China, 310016
China
Novartis Investigative Site Active, not recruiting
Beijing, China, 100029
Novartis Investigative Site Active, not recruiting
Beijing, China, 100034
Novartis Investigative Site Active, not recruiting
Chongqing, China, 400037
Novartis Investigative Site Active, not recruiting
Jinan, China, 250012
Novartis Investigative Site Active, not recruiting
Nanjing, China, 210036
Novartis Investigative Site Active, not recruiting
Shanghai, China, 200025
Novartis Investigative Site Active, not recruiting
Shanghai, China, 200031
Novartis Investigative Site Active, not recruiting
Shanghai, China, 200032
Novartis Investigative Site Active, not recruiting
Shanghai, China, 200080
Novartis Investigative Site Active, not recruiting
Urumqi, China, 830054
Colombia
Novartis Investigative Site Active, not recruiting
Barranquilla, Atlantico, Colombia
Novartis Investigative Site Active, not recruiting
Barranquilla, Colombia
Novartis Investigative Site Completed
Bogota, Colombia
Novartis Investigative Site Active, not recruiting
Florida Blanca, Colombia
Novartis Investigative Site Withdrawn
Medellin, Colombia
Novartis Investigative Site Active, not recruiting
Medellin, Colombia
Croatia
Novartis Investigative Site Active, not recruiting
Varazdin, HRV, Croatia, 42000
Novartis Investigative Site Withdrawn
Krapinske Toplice, Croatia, 49217
Novartis Investigative Site Active, not recruiting
Rijeka, Croatia, 51000
Novartis Investigative Site Active, not recruiting
Zadar, Croatia, 23000
Novartis Investigative Site Active, not recruiting
Zagreb, Croatia, 10000
Novartis Investigative Site Terminated
Zagreb, Croatia, 10000
Czech Republic
Novartis Investigative Site Active, not recruiting
Policska, CZE, Czech Republic, 57201
Novartis Investigative Site Active, not recruiting
Praha 2, CZE, Czech Republic, 128 08
Novartis Investigative Site Active, not recruiting
Usti nad Labem, CZE, Czech Republic, 400 01
Novartis Investigative Site Active, not recruiting
Brandys nad Labem, Czech Republic, 250 01
Novartis Investigative Site Active, not recruiting
Brno, Czech Republic, 60200
Novartis Investigative Site Completed
Chomutov, Czech Republic, 43002
Novartis Investigative Site Active, not recruiting
CZE, Czech Republic, 11000
Novartis Investigative Site Active, not recruiting
Ivancice, Czech Republic, 66491
Novartis Investigative Site Active, not recruiting
Kladno, Czech Republic, 272 80
Novartis Investigative Site Active, not recruiting
Kolin, Czech Republic, 280 20
Novartis Investigative Site Active, not recruiting
Liberec, Czech Republic, 460 05
Novartis Investigative Site Active, not recruiting
Louny, Czech Republic
Novartis Investigative Site Active, not recruiting
Marianske lazne, Czech Republic, 353 01
Novartis Investigative Site Active, not recruiting
Ostrava, Czech Republic, 70200
Novartis Investigative Site Active, not recruiting
Plzen, Czech Republic, 30100
Novartis Investigative Site Terminated
Praha 11, Czech Republic, 148 00
Novartis Investigative Site Active, not recruiting
Praha 4, Czech Republic, 140 21
Novartis Investigative Site Active, not recruiting
Roznov pod Radhostem, Czech Republic, 756 61
Novartis Investigative Site Active, not recruiting
Svitavy, Czech Republic, 568 25
Novartis Investigative Site Active, not recruiting
Trebic, Czech Republic, 674 01
Novartis Investigative Site Active, not recruiting
Uherske Hradiste, Czech Republic, 68601
Novartis Investigative Site Active, not recruiting
Usti nad Labem, Czech Republic, 400 01
Novartis Investigative Site Active, not recruiting
Znojmo, Czech Republic, 66902
Denmark
Novartis Investigative Site Withdrawn
Copenhagen NV, Denmark, DK-2400
Novartis Investigative Site Active, not recruiting
Copenhagen, Denmark, 2100
Novartis Investigative Site Active, not recruiting
Esbjerg, Denmark, DK-6700
Novartis Investigative Site Active, not recruiting
Herlev, Denmark, 2730
Novartis Investigative Site Active, not recruiting
Hvidovre, Denmark, 2650
Novartis Investigative Site Active, not recruiting
Randers, Denmark, 8930
Novartis Investigative Site Withdrawn
Slagelse, Denmark, DK-4200
Novartis Investigative Site Active, not recruiting
Svendborg, Denmark, 5700
Novartis Investigative Site Active, not recruiting
Viborg, Denmark, DK-8800
Finland
Novartis Investigative Site Active, not recruiting
Espoo, Finland, 02740
Novartis Investigative Site Active, not recruiting
Jyvaskyla, Finland, 40620
Novartis Investigative Site Active, not recruiting
Oulu, Finland, 90220
Novartis Investigative Site Active, not recruiting
Tampere, Finland, 33520
France
Novartis Investigative Site Active, not recruiting
Bayonne, Bayonne cedex, France, 64109
Novartis Investigative Site Active, not recruiting
Besancon Cedex, France, 25030
Novartis Investigative Site Active, not recruiting
Beziers Cedex, France, 34525
Novartis Investigative Site Active, not recruiting
Bordeaux Cedex, France, 33075
Novartis Investigative Site Active, not recruiting
Grenoble, France, 38043
Novartis Investigative Site Active, not recruiting
Le Kremlin Bicetre, France, 94275
Novartis Investigative Site Active, not recruiting
Lille Cedex, France, 59000
Novartis Investigative Site Withdrawn
Lille, France, 59037
Novartis Investigative Site Active, not recruiting
Lyon, France, F-69001
Novartis Investigative Site Active, not recruiting
Montpellier, France, 34059
Novartis Investigative Site Active, not recruiting
Paris cedex 10, France, 75010
Novartis Investigative Site Withdrawn
Paris, France, 75012
Novartis Investigative Site Active, not recruiting
Poitiers, France, 86000
Novartis Investigative Site Active, not recruiting
Pontoise, France, F-95300
Novartis Investigative Site Active, not recruiting
Rennes Cedex 9, France, 35033
Novartis Investigative Site Active, not recruiting
Toulouse Cedex, France, 31059
Novartis Investigative Site Active, not recruiting
Tourcoing, France, 59208
Novartis Investigative Site Active, not recruiting
Vandoeuvre Les Nancy, France, 54511
Germany
Novartis Investigative Site Active, not recruiting
Aachen, Germany, 52074
Novartis Investigative Site Active, not recruiting
Bad Homburg, Germany, 61348
Novartis Investigative Site Active, not recruiting
Bad Krozingen, Germany, 79189
Novartis Investigative Site Active, not recruiting
Bamberg, Germany, 96049
Novartis Investigative Site Active, not recruiting
Berlin-Buch, Germany, 13125
Novartis Investigative Site Terminated
Berlin, Germany, 10249
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 10789
Novartis Investigative Site Terminated
Berlin, Germany, 10967
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 12203
Novartis Investigative Site Withdrawn
Berlin, Germany, 12552
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 12683
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 13086
Novartis Investigative Site Withdrawn
Berlin, Germany, 13347
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 13353
Novartis Investigative Site Active, not recruiting
Berlin, Germany, 13405
Novartis Investigative Site Active, not recruiting
Chemnitz, Germany, 09126
Novartis Investigative Site Active, not recruiting
Chemnitz, Germany, 09130
Novartis Investigative Site Active, not recruiting
Dessau-Roßlau, Germany, 06846
Novartis Investigative Site Terminated
Dietzenbach, Germany, 63128
Novartis Investigative Site Terminated
Dinkelsbühl, Germany, 91550
Novartis Investigative Site Withdrawn
Dortmund, Germany, 44137
Novartis Investigative Site Active, not recruiting
Dresden, Germany, 01099
Novartis Investigative Site Active, not recruiting
Dresden, Germany, 01277
Novartis Investigative Site Active, not recruiting
Dresden, Germany, 01307
Novartis Investigative Site Active, not recruiting
Dresden, Germany, 01309
Novartis Investigative Site Active, not recruiting
Duisburg, Germany, 47137
Novartis Investigative Site Active, not recruiting
Eilenburg, Germany, D 04838
Novartis Investigative Site Active, not recruiting
Elsterwerda, Germany, 04910
Novartis Investigative Site Active, not recruiting
Essen, Germany, 45355
Novartis Investigative Site Terminated
Frankfurt, Germany, 60488
Novartis Investigative Site Active, not recruiting
Frankfurt, Germany, 60594
Novartis Investigative Site Active, not recruiting
Frankfurt, Germany, 65929
Novartis Investigative Site Withdrawn
Freiburg, Germany, 79106
Novartis Investigative Site Terminated
Goettingen, Germany, 37075
Novartis Investigative Site Active, not recruiting
Hamburg, Germany, 20099
Novartis Investigative Site Active, not recruiting
Hamburg, Germany, 20246
Novartis Investigative Site Active, not recruiting
Hamburg, Germany, 22041
Novartis Investigative Site Active, not recruiting
Hamburg, Germany, 22765
Novartis Investigative Site Active, not recruiting
Hassloch, Germany, 67454
Novartis Investigative Site Active, not recruiting
Heidenau, Germany, 01809
Novartis Investigative Site Terminated
Heide, Germany, 25746
Novartis Investigative Site Withdrawn
Hemsbach, Germany, 69502
Novartis Investigative Site Active, not recruiting
Heppenheim, Germany, 64646
Novartis Investigative Site Active, not recruiting
Homburg, Germany, 66421
Novartis Investigative Site Withdrawn
Huy / OT Anderbeck, Germany, 38836
Novartis Investigative Site Active, not recruiting
Ingelheim, Germany, 55218
Novartis Investigative Site Active, not recruiting
Jena, Germany, 07740
Novartis Investigative Site Active, not recruiting
Kassel, Germany, 34121
Novartis Investigative Site Active, not recruiting
Kleve, Germany, 47533
Novartis Investigative Site Active, not recruiting
Koblenz, Germany, 56068
Novartis Investigative Site Active, not recruiting
Koeln, Germany, 51605
Novartis Investigative Site Active, not recruiting
Leipzig, Germany, 04103
Novartis Investigative Site Withdrawn
Leipzig, Germany, 04315
Novartis Investigative Site Active, not recruiting
Loehne, Germany, 32584
Novartis Investigative Site Terminated
Ludwigsburg, Germany, 71634
Novartis Investigative Site Withdrawn
Ludwigsburg, Germany, 71640
Novartis Investigative Site Active, not recruiting
Ludwigshafen, Germany, 67071
Novartis Investigative Site Active, not recruiting
Lutherstadt Wittenberg, Germany, 06886
Novartis Investigative Site Active, not recruiting
Lüneburg, Germany, 21339
Novartis Investigative Site Active, not recruiting
Mainz, Germany, 55116
Novartis Investigative Site Terminated
Mannheim, Germany, 68165
Novartis Investigative Site Terminated
Markkleeberg, Germany, 04416
Novartis Investigative Site Active, not recruiting
Meißen, Germany, 01662
Novartis Investigative Site Active, not recruiting
Memmingen, Germany, 87700
Novartis Investigative Site Withdrawn
Merseburg, Germany, 06217
Novartis Investigative Site Active, not recruiting
Muehldorf am Inn, Germany, 84453
Novartis Investigative Site Active, not recruiting
Muehldorf, Germany, 84453
Novartis Investigative Site Terminated
Muehlheim an der Ruhr, Germany, 45468
Novartis Investigative Site Active, not recruiting
Muenster, Germany, 48149
Novartis Investigative Site Active, not recruiting
Munchen, Germany, 80992
Novartis Investigative Site Active, not recruiting
Munich, Germany, 80638
Novartis Investigative Site Withdrawn
Mönchengladbach, Germany, 41063
Novartis Investigative Site Active, not recruiting
Nienburg, Germany, 31582
Novartis Investigative Site Active, not recruiting
Northeim, Germany, 37154
Novartis Investigative Site Terminated
Nurnberg, Germany, 90402
Novartis Investigative Site Withdrawn
Oldenburg, Germany, 26133
Novartis Investigative Site Active, not recruiting
Oschatz, Germany, 04758
Novartis Investigative Site Active, not recruiting
Papenburg, Germany, 26871
Novartis Investigative Site Withdrawn
Peine, Germany, 31224
Novartis Investigative Site Active, not recruiting
Reinfeld, Germany, 23858
Novartis Investigative Site Active, not recruiting
Riesa, Germany, 01589
Novartis Investigative Site Active, not recruiting
Rodgau, Germany, 63110
Novartis Investigative Site Active, not recruiting
Siegen, Germany, 57072
Novartis Investigative Site Withdrawn
Stuttgart, Germany, 70378
Novartis Investigative Site Withdrawn
Ulm, Germany, 89073
Novartis Investigative Site Active, not recruiting
Ulm, Germany, 89077
Novartis Investigative Site Terminated
Vilshofen, Germany, 94474
Novartis Investigative Site Terminated
Wangen, Germany, 88239
Novartis Investigative Site Active, not recruiting
Wermsdorf, Germany, 04779
Novartis Investigative Site Active, not recruiting
Weyhe, Germany, 28844
Novartis Investigative Site Active, not recruiting
Witten, Germany, 58455
Novartis Investigative Site Active, not recruiting
Wuerzburg, Germany, 97078
Novartis Investigative Site Withdrawn
Zwenkau, Germany, 04442
Greece
Novartis Investigative Site Withdrawn
Heraklion, Crete, GR, Greece, 71110
Novartis Investigative Site Active, not recruiting
Ioannina, GR, Greece, 45110
Novartis Investigative Site Active, not recruiting
Larissa, GR, Greece, 411 10
Novartis Investigative Site Active, not recruiting
Athens, Greece, 15562
Novartis Investigative Site Active, not recruiting
Athens, Greece, GR 11527
Novartis Investigative Site Active, not recruiting
Athens, Greece, GR 14233
Novartis Investigative Site Withdrawn
Athens, Greece, GR 176 74
Novartis Investigative Site Active, not recruiting
Chaidari, Greece, 12461
Novartis Investigative Site Active, not recruiting
Thessaloniki, Greece, 54636
Novartis Investigative Site Active, not recruiting
Thessaloniki, Greece, 54642
Guatemala
Novartis Investigative Site Active, not recruiting
Guatemala City, Guatemala, 01010
Novartis Investigative Site Active, not recruiting
Guatemala City, Guatemala, 01011
Novartis Investigative Site Active, not recruiting
Guatemala City, Guatemala, 01015
Novartis Investigative Site Active, not recruiting
Guatemala City, Guatemala, 10110
Novartis Investigative Site Active, not recruiting
Guatemala City, Guatemala
Novartis Investigative Site Withdrawn
Quetzaltenango, Guatemala, 09001
Novartis Investigative Site Active, not recruiting
Quetzaltenango, Guatemala, 09001
Hungary
Novartis Investigative Site Active, not recruiting
Budapest, Hungary, 1042
Novartis Investigative Site Active, not recruiting
Budapest, Hungary, 1085
Novartis Investigative Site Active, not recruiting
Budapest, Hungary, 1134
Novartis Investigative Site Active, not recruiting
Budapest, Hungary, 1145
Novartis Investigative Site Active, not recruiting
Budapest, Hungary, H 1096
Novartis Investigative Site Active, not recruiting
Cegled, Hungary, 2700
Novartis Investigative Site Withdrawn
Gyula, Hungary, 5700
Novartis Investigative Site Active, not recruiting
Kistarcsa, Hungary, 2143
Novartis Investigative Site Active, not recruiting
Mako, Hungary, 6900
Novartis Investigative Site Active, not recruiting
Mohacs, Hungary, 7700
Novartis Investigative Site Active, not recruiting
Nyiregyháza, Hungary, 4400
Novartis Investigative Site Active, not recruiting
Pecs, Hungary, 7623
Novartis Investigative Site Recruiting
Pecs, Hungary, 7624
Novartis Investigative Site Active, not recruiting
Pécs, Hungary, 7623
Novartis Investigative Site Active, not recruiting
Szeged, Hungary, H-6725
Novartis Investigative Site Active, not recruiting
Szekesfehervar, Hungary, H-8000
Novartis Investigative Site Active, not recruiting
Zalaegerszeg, Hungary, 8900
India
Novartis Investigative Site Active, not recruiting
Guntur, Andhra Pradesh, India, 522001
Novartis Investigative Site Active, not recruiting
Vishakhapatnam, Andhra Pradesh, India, 532 002
Novartis Investigative Site Active, not recruiting
New Delhi, Delhi, India, 110 060
Novartis Investigative Site Active, not recruiting
Surat, Gujarat, India, 395 002
Novartis Investigative Site Active, not recruiting
Chandigarh, Haryana, India, 160 030
Novartis Investigative Site Active, not recruiting
Gurgaon, Haryana, India, 122001
Novartis Investigative Site Active, not recruiting
Bangalore, Karnataka, India, 560 002
Novartis Investigative Site Active, not recruiting
Kochi, Kerala, India, 683 594
Novartis Investigative Site Active, not recruiting
Pune, Maharashtra, India, 411 030
Novartis Investigative Site Active, not recruiting
Ludhiana, Punjab, India, 141002
Novartis Investigative Site Active, not recruiting
Bikaner, Rajasthan, India, 334003
Novartis Investigative Site Active, not recruiting
Chennai, Tamil Nadu, India, 600037
Novartis Investigative Site Active, not recruiting
Chennai, Tamil Nadu, India, 600081
Novartis Investigative Site Active, not recruiting
Madurai, Tamil Nadu, India, 625107
Novartis Investigative Site Active, not recruiting
Kolkata, West Bengal, India, 700 020
Novartis Investigative Site Active, not recruiting
Ahmedabad, India, 380052
Novartis Investigative Site Active, not recruiting
New Delhi, India, 110025
Israel
Novartis Investigative Site Active, not recruiting
Hadera, Israel, 38100
Novartis Investigative Site Active, not recruiting
Hadera, Israel
Novartis Investigative Site Active, not recruiting
Haifa, Israel, 3339419
Novartis Investigative Site Active, not recruiting
Haifa, Israel, 3525408
Novartis Investigative Site Active, not recruiting
Lower Galilee, Israel, 15208
Novartis Investigative Site Active, not recruiting
Nahariya, Israel, 22100
Novartis Investigative Site Active, not recruiting
Petach Tikva, Israel, 49100
Novartis Investigative Site Active, not recruiting
Ramat Gan, Israel, 5266202
Novartis Investigative Site Active, not recruiting
Rehovot, Israel, 76100
Novartis Investigative Site Active, not recruiting
Tel Giborim, Holon, Israel, 58100
Italy
Novartis Investigative Site Active, not recruiting
Aosta, AO, Italy, 11100
Novartis Investigative Site Active, not recruiting
Cortona, AR, Italy, 52044
Novartis Investigative Site Active, not recruiting
Bergamo, BG, Italy, 24128
Novartis Investigative Site Active, not recruiting
Treviglio, BG, Italy, 24047
Novartis Investigative Site Active, not recruiting
Bologna, BO, Italy, 40138
Novartis Investigative Site Active, not recruiting
Brescia, BS, Italy, 25123
Novartis Investigative Site Terminated
San Fermo della Battaglia, CO, Italy, 22020
Novartis Investigative Site Active, not recruiting
Cona, FE, Italy, 44100
Novartis Investigative Site Active, not recruiting
Pozzilli, IS, Italy, 86077
Novartis Investigative Site Active, not recruiting
Monza, MB, Italy, 20900
Novartis Investigative Site Active, not recruiting
Messina, ME, Italy, 98125
Novartis Investigative Site Active, not recruiting
Milano, MI, Italy, 20162
Novartis Investigative Site Active, not recruiting
Vimercate, MI, Italy, 200059
Novartis Investigative Site Terminated
Palermo, PA, Italy, 90146
Novartis Investigative Site Terminated
Piacenza, PC, Italy, 29100
Novartis Investigative Site Withdrawn
Padova, PD, Italy, 35100
Novartis Investigative Site Active, not recruiting
Padova, PD, Italy, 35128
Novartis Investigative Site Active, not recruiting
Perugia, PG, Italy, 06100
Novartis Investigative Site Active, not recruiting
Perugia, PG, Italy, 06129
Novartis Investigative Site Withdrawn
Pisa, PI, Italy, 56126
Novartis Investigative Site Active, not recruiting
Pavia, PV, Italy, 27100
Novartis Investigative Site Active, not recruiting
Albano Laziale, RM, Italy, 00041
Novartis Investigative Site Active, not recruiting
Roma, RM, Italy, 00163
Novartis Investigative Site Withdrawn
Roma, RM, Italy, 00184
Novartis Investigative Site Active, not recruiting
Roma, RM, Italy, 00189
Novartis Investigative Site Active, not recruiting
Sassari, SS, Italy, 07100
Novartis Investigative Site Withdrawn
Torino, TO, Italy, 10126
Novartis Investigative Site Active, not recruiting
Trieste, TS, Italy, 34142
Novartis Investigative Site Active, not recruiting
Trieste, TS, Italy, 34149
Novartis Investigative Site Terminated
Vittorio Veneto, TV, Italy, 31029
Novartis Investigative Site Active, not recruiting
Palmanova, UD, Italy, 33057
Novartis Investigative Site Active, not recruiting
San Daniele Del Friuli, UD, Italy, 33038
Novartis Investigative Site Active, not recruiting
Saronno, Va, Italy, 21047
Novartis Investigative Site Active, not recruiting
Venezia, VE, Italy, 30174
Novartis Investigative Site Active, not recruiting
Milano, Italy, 20149
Novartis Investigative Site Active, not recruiting
Napoli, Italy, 80131
Novartis Investigative Site Terminated
Novara, Italy, 28100
Japan
Novartis Investigative Site Active, not recruiting
Seto-city, Aichi, Japan, 489-8642
Novartis Investigative Site Active, not recruiting
Chikushino-city, Fukuka, Japan, 818-8516
Novartis Investigative Site Active, not recruiting
Ogaki-city, Gifu, Japan, 503-8502
Novartis Investigative Site Active, not recruiting
Maebashi-city, Gunma, Japan, 371-8511
Novartis Investigative Site Withdrawn
Hatsukaichi-city, Hiroshima, Japan, 738-8503
Novartis Investigative Site Active, not recruiting
Amagasaki-city, Hyogo, Japan, 660-8550
Novartis Investigative Site Active, not recruiting
Kanazawa, Ishikawa, Japan, 920-8650
Novartis Investigative Site Active, not recruiting
Morioka, Iwate, Japan, 020-0066
Novartis Investigative Site Active, not recruiting
Kanonji-city, Kagawa, Japan, 769-1695
Novartis Investigative Site Active, not recruiting
Takamatsu-city, Kagawa, Japan, 760-8557
Novartis Investigative Site Active, not recruiting
Yokohama-city, Kanagawa, Japan, 227-8501
Novartis Investigative Site Active, not recruiting
Yokohama-city, Kanagawa, Japan, 236-0051
Novartis Investigative Site Active, not recruiting
Sendai-city, Miyagi, Japan, 980-8574
Novartis Investigative Site Terminated
Sendai-city, Miyagi, Japan, 981-3133
Novartis Investigative Site Active, not recruiting
Kashihara-city, Nara, Japan, 634-8522
Novartis Investigative Site Terminated
Oita-city, Oita, Japan, 870-0192
Novartis Investigative Site Active, not recruiting
Sayama-city, Saitama, Japan, 350-1305
Novartis Investigative Site Active, not recruiting
Kusatsu-city, Shiga, Japan, 525-8585
Novartis Investigative Site Active, not recruiting
Chiyoda-ku, Tokyo, Japan, 101-8309
Novartis Investigative Site Withdrawn
Chuo-ku, Tokyo, Japan, 104-8560
Novartis Investigative Site Active, not recruiting
Hachioji-city, Tokyo, Japan, 192-0918
Novartis Investigative Site Active, not recruiting
Itabashi-ku, Tokyo, Japan, 173-8610
Novartis Investigative Site Active, not recruiting
Shinagawa-ku, Tokyo, Japan, 142-8666
Korea, Republic of
Novartis Investigative Site Active, not recruiting
Gyeonggi-do, Bucheon-si, Korea, Republic of, 422-711
Novartis Investigative Site Active, not recruiting
Cheongju-si, Chungcheongbuk-do, Korea, Republic of, 28644
Novartis Investigative Site Active, not recruiting
Wonju, Gangwon-do, Korea, Republic of, 26427
Novartis Investigative Site Completed
Suwon, Gyeonggi-do, Korea, Republic of, 442-723
Novartis Investigative Site Active, not recruiting
Seongnam, Gyeonggi, Korea, Republic of, 13620
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Korea, Republic of, 03080
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Korea, Republic of, 05505
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Korea, Republic of, 06351
Novartis Investigative Site Withdrawn
Seoul, Korea, Korea, Republic of, 06591
Novartis Investigative Site Recruiting
Busan, Korea, Republic of, 49241
Novartis Investigative Site Active, not recruiting
Daegu, Korea, Republic of, 705-718
Novartis Investigative Site Active, not recruiting
Incheon, Korea, Republic of, 22332
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Republic of, 08308
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Republic of, 120-752
Novartis Investigative Site Withdrawn
Seoul, Korea, Republic of, 134-701
Novartis Investigative Site Active, not recruiting
Seoul, Korea, Republic of, 136-705
Mexico
Novartis Investigative Site Recruiting
Torreon, Coahulia, Mexico, 27000
Novartis Investigative Site Recruiting
Mexico, Distrito Federal, Mexico, 14080
Novartis Investigative Site Active, not recruiting
Leon, Guanajuato, Mexico, 37530
Novartis Investigative Site Active, not recruiting
Zapopan, Jalisco, Mexico, 45200
Novartis Investigative Site Active, not recruiting
San Juan del Rio, Queretaro, Mexico, 76800
Novartis Investigative Site Active, not recruiting
San Luis Potosi, San Luis Potosí, Mexico, 78240
Novartis Investigative Site Recruiting
Culiacan, Sinaloa, Mexico, CP:83230
Novartis Investigative Site Active, not recruiting
Aguascalientes, Mexico, 20230
Novartis Investigative Site Recruiting
Queretaro, Mexico, 76000
Novartis Investigative Site Active, not recruiting
San Luis Potosi, Mexico, 78200
Novartis Investigative Site Active, not recruiting
San Luis Potosí, Mexico, 78200
Netherlands
Novartis Investigative Site Active, not recruiting
Den Haag, NL, Netherlands, 2597 AX
Novartis Investigative Site Active, not recruiting
Almelo, PP, Netherlands, 7609
Novartis Investigative Site Active, not recruiting
Apeldoorn, Netherlands, 7334 DZ
Novartis Investigative Site Active, not recruiting
Arnhem, Netherlands, 6815 AD
Novartis Investigative Site Active, not recruiting
Blaricum, Netherlands, 1261 AN
Novartis Investigative Site Active, not recruiting
Den Haag, Netherlands, 2512 VA
Novartis Investigative Site Active, not recruiting
Ede, Netherlands, 6716 RP
Novartis Investigative Site Active, not recruiting
Gouda, Netherlands, 2800 BB
Novartis Investigative Site Active, not recruiting
Groningen, Netherlands, 9713 GZ
Novartis Investigative Site Active, not recruiting
Hardenberg, Netherlands, 7770 AA
Novartis Investigative Site Active, not recruiting
Harderwijk, Netherlands, 3840 AC
Novartis Investigative Site Active, not recruiting
Nijmegen, Netherlands, 6525 GA
Novartis Investigative Site Active, not recruiting
Rotterdam, Netherlands, 3015 CE
Novartis Investigative Site Active, not recruiting
Sneek, Netherlands, 8601 ZK
Novartis Investigative Site Active, not recruiting
Tilburg, Netherlands, 5022 GC
Novartis Investigative Site Terminated
Zwolle, Netherlands, 8025 AB
Norway
Novartis Investigative Site Withdrawn
Hamar, Norway, 2316
Novartis Investigative Site Active, not recruiting
Hønefoss, Norway, 3501
Novartis Investigative Site Active, not recruiting
Lørenskog, Norway, NO-1478
Novartis Investigative Site Active, not recruiting
Oslo, Norway, 0407
Novartis Investigative Site Active, not recruiting
Stavanger, Norway, 4068
Novartis Investigative Site Active, not recruiting
Tromsoe, Norway, NO-9038
Peru
Novartis Investigative Site Active, not recruiting
Bellavista, Lima, Peru, Callao 02
Novartis Investigative Site Active, not recruiting
Cercado de Lima, Lima, Peru, 01
Novartis Investigative Site Active, not recruiting
Jesus Maria, Lima, Peru, 11
Novartis Investigative Site Active, not recruiting
Miraflores, Lima, Peru, 18
Novartis Investigative Site Active, not recruiting
San Isidro, Lima, Peru, 27
Philippines
Novartis Investigative Site Active, not recruiting
Lipa City, Batangas, Philippines, 4217
Novartis Investigative Site Active, not recruiting
Quezon City, Manila, Philippines, 1100
Novartis Investigative Site Completed
Manila, Philippines, 1008
Novartis Investigative Site Active, not recruiting
Quezon City, Philippines, 1100
Novartis Investigative Site Active, not recruiting
Quezon City, Philippines, 1102
Poland
Novartis Investigative Site Completed
Gdansk, Poland, 80-141
Novartis Investigative Site Active, not recruiting
Gdynia, Poland, 81-157
Novartis Investigative Site Withdrawn
Gdynia, Poland, 81-472
Novartis Investigative Site Active, not recruiting
Gdynia, Poland, 81-548
Novartis Investigative Site Active, not recruiting
Grodzisk Mazowiecki, Poland, 05-825
Novartis Investigative Site Active, not recruiting
Katowice, Poland, 40-645
Novartis Investigative Site Active, not recruiting
Krakow, Poland, 30-015
Novartis Investigative Site Active, not recruiting
Krakow, Poland, 31 501
Novartis Investigative Site Active, not recruiting
Lodz, Poland, 92-213
Novartis Investigative Site Active, not recruiting
Lublin, Poland, 20-363
Novartis Investigative Site Completed
Piaseczno, Poland, 05-500
Novartis Investigative Site Active, not recruiting
Sandomierz, Poland, 27-600
Novartis Investigative Site Active, not recruiting
Staszów, Poland, 28-200
Novartis Investigative Site Recruiting
Torun, Poland, 87-100
Novartis Investigative Site Active, not recruiting
Warszawa/Anin, Poland, 04-761
Novartis Investigative Site Active, not recruiting
Warszawa, Poland, 02-097
Novartis Investigative Site Active, not recruiting
Warszawa, Poland, 04-154
Novartis Investigative Site Active, not recruiting
Zabrze, Poland, 41-800
Novartis Investigative Site Active, not recruiting
Zamosc, Poland, 22-400
Romania
Novartis Investigative Site Active, not recruiting
Pitesti, Arges, Romania, 110438
Novartis Investigative Site Active, not recruiting
Bucuresti, District 1, Romania, 014461
Novartis Investigative Site Active, not recruiting
Craiova, Jud. Dolj, Romania, 200497
Novartis Investigative Site Active, not recruiting
Sibiu, Jud. Iasi, Romania, 550371
Novartis Investigative Site Active, not recruiting
Timisoara, jud. Timis, Romania, 300359
Novartis Investigative Site Active, not recruiting
Braila, ROM, Romania, 810249
Novartis Investigative Site Active, not recruiting
Timisoara, Timis, Romania, 300125
Novartis Investigative Site Active, not recruiting
Arad, Romania, 310158
Novartis Investigative Site Active, not recruiting
Baia Mare, Romania, 430222
Novartis Investigative Site Active, not recruiting
Bucharest, Romania, 050098
Novartis Investigative Site Active, not recruiting
Bucuresti, Romania, 062272
Novartis Investigative Site Active, not recruiting
Oradea, Romania, 410169
Novartis Investigative Site Active, not recruiting
Targu Mures, Romania, 540143
Novartis Investigative Site Recruiting
Targu-Mures, Romania, 540142
Novartis Investigative Site Active, not recruiting
Timisoara, Romania, 300041
Novartis Investigative Site Active, not recruiting
Timisoara, Romania, 300079
Russian Federation
Novartis Investigative Site Active, not recruiting
Saint Petersburg, Russia, Russian Federation, 197022
Novartis Investigative Site Active, not recruiting
Chelyabinsk, Russian Federation, 454021
Novartis Investigative Site Active, not recruiting
Ekaterinburg, Russian Federation, 620028
Novartis Investigative Site Active, not recruiting
Ekaterinburg, Russian Federation, 620137
Novartis Investigative Site Active, not recruiting
Ivanovo, Russian Federation, 153012
Novartis Investigative Site Active, not recruiting
Izhevsk, Russian Federation, 426009
Novartis Investigative Site Active, not recruiting
Izhevsk, Russian Federation, 426063
Novartis Investigative Site Active, not recruiting
Kemerovo, Russian Federation, 650029
Novartis Investigative Site Active, not recruiting
Kemerovo, Russian Federation, 650099
Novartis Investigative Site Active, not recruiting
Kirov, Russian Federation, 610014
Novartis Investigative Site Active, not recruiting
Kirov, Russian Federation, 610027
Novartis Investigative Site Active, not recruiting
Moscow, Russian Federation, 101990
Novartis Investigative Site Active, not recruiting
Moscow, Russian Federation, 117198
Novartis Investigative Site Active, not recruiting
Moscow, Russian Federation, 121309
Novartis Investigative Site Active, not recruiting
Moscow, Russian Federation, 121552
Novartis Investigative Site Active, not recruiting
N.Novgorod, Russian Federation, 603005
Novartis Investigative Site Active, not recruiting
Perm, Russian Federation, 614990
Novartis Investigative Site Active, not recruiting
Rostov-on-Don, Russian Federation, 344022
Novartis Investigative Site Active, not recruiting
Rostov-on-Don, Russian Federation, 344068
Novartis Investigative Site Active, not recruiting
Saint Petersburg, Russian Federation, 197022
Novartis Investigative Site Active, not recruiting
Saint Petersburg, Russian Federation, 199106
Novartis Investigative Site Active, not recruiting
Saint-Petersburg, Russian Federation, 194044
Novartis Investigative Site Active, not recruiting
Saint-Petersburg, Russian Federation, 195257
Novartis Investigative Site Active, not recruiting
Saint-Petersburg, Russian Federation, 197341
Novartis Investigative Site Active, not recruiting
Saratov, Russian Federation, 410012
Novartis Investigative Site Active, not recruiting
Smolensk, Russian Federation, 214018
Novartis Investigative Site Active, not recruiting
St Petersburg, Russian Federation, 196601
Novartis Investigative Site Active, not recruiting
St-Petersburg, Russian Federation, 194295
Novartis Investigative Site Active, not recruiting
St. Petersburg, Russian Federation, 197706
Novartis Investigative Site Active, not recruiting
St.- Petersburg, Russian Federation, 197110
Novartis Investigative Site Withdrawn
Syktyvkar, Russian Federation, 167981
Novartis Investigative Site Active, not recruiting
Yaroslavl, Russian Federation, 150003
Serbia
Novartis Investigative Site Active, not recruiting
Belgrade, Serbia, 11000
Novartis Investigative Site Active, not recruiting
Beograd, Serbia, 11040
Novartis Investigative Site Active, not recruiting
Niska Banja, Serbia, 18205
Novartis Investigative Site Active, not recruiting
Nis, Serbia, 18000
Singapore
Novartis Investigative Site Active, not recruiting
Singapore, Singapore, 119074
Novartis Investigative Site Active, not recruiting
Singapore, Singapore, 169609
Novartis Investigative Site Active, not recruiting
Singapore, Singapore, 308433
Novartis Investigative Site Active, not recruiting
Singapore, Singapore, 529889
Novartis Investigative Site Active, not recruiting
Singapore, Singapore, 768825
Slovakia
Novartis Investigative Site Active, not recruiting
Brezno, Slovak Republic, Slovakia, 977 42
Novartis Investigative Site Active, not recruiting
Komarno, Slovak Republic, Slovakia, 94575
Novartis Investigative Site Active, not recruiting
Levice, Slovak Republic, Slovakia, 93401
Novartis Investigative Site Active, not recruiting
Namestovo, Slovak Republic, Slovakia, 02901
Novartis Investigative Site Active, not recruiting
Povazska Bystrica, Slovak republic, Slovakia, 01701
Novartis Investigative Site Active, not recruiting
Presov, Slovak Republic, Slovakia, 08001
Novartis Investigative Site Terminated
Velky Krtis, Slovak Republic, Slovakia, 990 01
Novartis Investigative Site Withdrawn
Banska Bystrica, Slovakia, 97401
Novartis Investigative Site Active, not recruiting
Bardejov, Slovakia, 085 01
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 821 07
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 831 01
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 833 48
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 841 07
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 842 31
Novartis Investigative Site Active, not recruiting
Bratislava, Slovakia, 851 01
Novartis Investigative Site Active, not recruiting
Kosice, Slovakia, 040 01
Novartis Investigative Site Active, not recruiting
Levice, Slovakia, 934 01
Novartis Investigative Site Completed
Lucenec, Slovakia, 984 01
Novartis Investigative Site Active, not recruiting
Lucenec, Slovakia, 98439
Novartis Investigative Site Active, not recruiting
Nitra, Slovakia, 949 01
Novartis Investigative Site Active, not recruiting
Nitra, Slovakia, 949 88
Novartis Investigative Site Active, not recruiting
Nove Zamky, Slovakia, 94002
Novartis Investigative Site Active, not recruiting
Nové Zámky, Slovakia, 940 01
Novartis Investigative Site Active, not recruiting
Piestany, Slovakia, 921 01
Novartis Investigative Site Active, not recruiting
Presov, Slovakia, 080 01
Novartis Investigative Site Active, not recruiting
Svidnik, Slovakia, 089 01
Novartis Investigative Site Active, not recruiting
Trebisov, Slovakia, 075 01
Novartis Investigative Site Active, not recruiting
Zilina, Slovakia, 012 07
Slovenia
Novartis Investigative Site Active, not recruiting
Golnik, Slovenia, 4204
Novartis Investigative Site Active, not recruiting
Ljubljana, Slovenia, 1000
South Africa
Novartis Investigative Site Recruiting
Mthatha, Eastern Cape, South Africa
Novartis Investigative Site Active, not recruiting
Bloemfontein, Free State, South Africa, 9301
Novartis Investigative Site Recruiting
Soweto, Gauteng, South Africa, 2013
Novartis Investigative Site Active, not recruiting
Durban, Kwa-Zulu Natal, South Africa, 4052
Novartis Investigative Site Recruiting
Paarl, Western Cape, South Africa, 7626
Novartis Investigative Site Active, not recruiting
Alberton, South Africa, 1449
Novartis Investigative Site Active, not recruiting
Bloemfontein, South Africa, 9301
Novartis Investigative Site Active, not recruiting
Cape Town, South Africa, 7505
Novartis Investigative Site Recruiting
Cape Town, South Africa, 7531
Novartis Investigative Site Active, not recruiting
Cape Town, South Africa, 7925
Novartis Investigative Site Active, not recruiting
Durban, South Africa, 4001
Novartis Investigative Site Completed
Durban, South Africa, 4110
Novartis Investigative Site Completed
Johannesburg, South Africa, 2193
Novartis Investigative Site Completed
Pretoria, South Africa, 0121
Novartis Investigative Site Recruiting
Tongaat, South Africa, 3300
Novartis Investigative Site Active, not recruiting
Western Cape, South Africa, 7130
Novartis Investigative Site Recruiting
Worcester, South Africa, 6850
Spain
Novartis Investigative Site Active, not recruiting
Almeria, Andalucia, Spain, 04120
Novartis Investigative Site Active, not recruiting
Cordoba, Andalucia, Spain, 14004
Novartis Investigative Site Active, not recruiting
Malaga, Andalucia, Spain, 29010
Novartis Investigative Site Active, not recruiting
Marbella, Andalucia, Spain, 29600
Novartis Investigative Site Active, not recruiting
Sanlúcar de Barrameda, Andalucia, Spain, 11540
Novartis Investigative Site Active, not recruiting
Sevilla, Andalucia, Spain, 41013
Novartis Investigative Site Active, not recruiting
Sevilla, Andalucia, Spain, 41014
Novartis Investigative Site Active, not recruiting
Oviedo, Asturias, Spain, 33011
Novartis Investigative Site Active, not recruiting
Sant Joan Despi, Barcelona, Spain, 08970
Novartis Investigative Site Active, not recruiting
Villamartin, Cadiz, Spain, 11650
Novartis Investigative Site Active, not recruiting
Santander, Cantabria, Spain, 39008
Novartis Investigative Site Active, not recruiting
Aranda de Duero, Castilla y Leon, Spain, 09400
Novartis Investigative Site Active, not recruiting
Leon, Castilla y Leon, Spain, 24071
Novartis Investigative Site Active, not recruiting
Lerida, Cataluna, Spain, 25198
Novartis Investigative Site Active, not recruiting
Badalona, Catalunya, Spain, 08916
Novartis Investigative Site Active, not recruiting
Barcelona, Catalunya, Spain, 08003
Novartis Investigative Site Active, not recruiting
Alzira, Comunidad Valenciana, Spain, 46600
Novartis Investigative Site Active, not recruiting
Valencia, Comunidad Valenciana, Spain, 46010
Novartis Investigative Site Active, not recruiting
Valencia, Comunidad Valenciana, Spain, 46014
Novartis Investigative Site Active, not recruiting
Valencia, Comunidad Valenciana, Spain, 46026
Novartis Investigative Site Active, not recruiting
Merida, Extremadura, Spain, 06800
Novartis Investigative Site Active, not recruiting
A Coruna, Galicia, Spain, 15006
Novartis Investigative Site Active, not recruiting
Santiago de Compostela, Galicia, Spain, 15706
Novartis Investigative Site Active, not recruiting
Olot, Girona, Spain, 17800
Novartis Investigative Site Active, not recruiting
Majadahonda, Madrid, Spain, 28222
Novartis Investigative Site Active, not recruiting
Mostoles, Madrid, Spain, 28935
Novartis Investigative Site Active, not recruiting
El Palmar, Murcia, Spain, 30120
Novartis Investigative Site Active, not recruiting
Ciudad Real, Spain, 13005
Novartis Investigative Site Active, not recruiting
Madrid, Spain, 28007
Novartis Investigative Site Active, not recruiting
Madrid, Spain, 28034
Novartis Investigative Site Active, not recruiting
Madrid, Spain, 28040
Novartis Investigative Site Active, not recruiting
Madrid, Spain, 28046
Sweden
Novartis Investigative Site Active, not recruiting
Danderyd, Sweden, 182 88
Novartis Investigative Site Active, not recruiting
Falun, Sweden, 791 82
Novartis Investigative Site Active, not recruiting
Goteborg, Sweden, 413 45
Novartis Investigative Site Active, not recruiting
Karlstad, Sweden, 652 30
Novartis Investigative Site Terminated
Linkoping, Sweden, 581 85
Novartis Investigative Site Active, not recruiting
Lund, Sweden, 222 21
Novartis Investigative Site Active, not recruiting
Stockholm, Sweden, 17176
Novartis Investigative Site Active, not recruiting
Vasteras, Sweden, s-721 89
Novartis Investigative Site Active, not recruiting
Örebro, Sweden, 701 85
Switzerland
Novartis Investigative Site Active, not recruiting
Basel, Switzerland, 4031
Novartis Investigative Site Active, not recruiting
Bern, Switzerland, 3010
Novartis Investigative Site Active, not recruiting
Biel, Switzerland, 2500
Novartis Investigative Site Active, not recruiting
Lausanne, Switzerland, 1011
Novartis Investigative Site Active, not recruiting
Lugano, Switzerland, 6903
Novartis Investigative Site Active, not recruiting
Zurich, Switzerland, 8091
Taiwan
Novartis Investigative Site Active, not recruiting
Yongkang, Tainan, Taiwan, 71004
Novartis Investigative Site Active, not recruiting
Tainan, Taiwan ROC, Taiwan, 70421
Novartis Investigative Site Active, not recruiting
Changhua, Taiwan, 500
Novartis Investigative Site Active, not recruiting
Kaohsiung, Taiwan, 807
Novartis Investigative Site Active, not recruiting
Taichung, Taiwan, 40447
Novartis Investigative Site Active, not recruiting
Taipei County, Taiwan, 22060
Novartis Investigative Site Active, not recruiting
Taipei, Taiwan, 10002
Novartis Investigative Site Active, not recruiting
Taipei, Taiwan, 112
Novartis Investigative Site Active, not recruiting
Yilan, Taiwan, 26058
Turkey
Novartis Investigative Site Active, not recruiting
Ankara, Turkey, 06100
Novartis Investigative Site Active, not recruiting
Balcova / Izmir, Turkey, 35340
Novartis Investigative Site Active, not recruiting
Fatih / Istanbul, Turkey, 34098
Novartis Investigative Site Active, not recruiting
Haydarpasa/Istanbul, Turkey, 34668
Novartis Investigative Site Active, not recruiting
Istanbul, Turkey, 34304
Novartis Investigative Site Active, not recruiting
Izmir, Turkey, 35040
Novartis Investigative Site Active, not recruiting
Kocaeli, Turkey, 41380
Novartis Investigative Site Active, not recruiting
Pendik / Istanbul, Turkey, 34899
Novartis Investigative Site Completed
Samsun, Turkey, 55139
Novartis Investigative Site Active, not recruiting
Sivas, Turkey, 58140
United Kingdom
Novartis Investigative Site Recruiting
High Wycombe, Buckinghamshire, United Kingdom, HP11 2TT
Novartis Investigative Site Active, not recruiting
Stockton on Tees, Cleveland, United Kingdom, TS19 8PE
Novartis Investigative Site Active, not recruiting
Darlington, Co Durham, United Kingdom, DL3 8SQ
Novartis Investigative Site Active, not recruiting
Durham, County Durham, United Kingdom, DH1 5TW
Novartis Investigative Site Active, not recruiting
Torquay, Devon, United Kingdom, TQ2 7AA
Novartis Investigative Site Active, not recruiting
Dorchester, Dorset, United Kingdom, DT1 2JY
Novartis Investigative Site Active, not recruiting
Peterborough, GBR, United Kingdom, PE3 6DA
Novartis Investigative Site Active, not recruiting
Basingstoke, Hampshire, United Kingdom, RG24 9NA
Novartis Investigative Site Active, not recruiting
Portsmouth, Hampshire, United Kingdom, PO6 3LY
Novartis Investigative Site Active, not recruiting
Oldham, Lancashire, United Kingdom, OL1 2JH
Novartis Investigative Site Recruiting
Harrow, Middlesex, United Kingdom, HA1 3UJ
Novartis Investigative Site Active, not recruiting
Whitby, North Yorkshire, United Kingdom, Y021 1SD
Novartis Investigative Site Active, not recruiting
Portadown, Nothern Ireland, United Kingdom, BT63 5QQ
Novartis Investigative Site Active, not recruiting
Wansford, Peterborough, United Kingdom, PE8 6PL
Novartis Investigative Site Recruiting
Midsomer Norton, Radstock, United Kingdom, BA3 2UH
Novartis Investigative Site Active, not recruiting
Glasgow, Scotland, United Kingdom, G12 8TA
Novartis Investigative Site Active, not recruiting
Taunton, Somerset, United Kingdom, TA1 5DA
Novartis Investigative Site Active, not recruiting
Gateshead, Tyne and Wear, United Kingdom, NE9 6SX
Novartis Investigative Site Active, not recruiting
South Shields, Tyne and Wear, United Kingdom, NE34 0PL
Novartis Investigative Site Active, not recruiting
Clydebank, West Dumbartonshire, United Kingdom, G81 4HX
Novartis Investigative Site Recruiting
Trowbridge, Wiltshire, United Kingdom, BA14 8QA
Novartis Investigative Site Active, not recruiting
Bath, United Kingdom, BA2 4BY
Novartis Investigative Site Active, not recruiting
Cheshire, United Kingdom, CW1 4QJ
Novartis Investigative Site Active, not recruiting
Coventry, United Kingdom, CV2 2DX
Novartis Investigative Site Withdrawn
Doncaster, United Kingdom, DN2 5LT
Novartis Investigative Site Active, not recruiting
Dundee, United Kingdom, DD1 9SY
Novartis Investigative Site Active, not recruiting
Glasgow, United Kingdom, G20 0XA
Novartis Investigative Site Active, not recruiting
Hull, United Kingdom, HU16 5JQ
Novartis Investigative Site Terminated
Leicester, United Kingdom, LE3 9QP
Novartis Investigative Site Recruiting
London, United Kingdom, SE5 9RS
Novartis Investigative Site Recruiting
London, United Kingdom, SW 6NP
Novartis Investigative Site Active, not recruiting
Newport, United Kingdom, NP20 2UB
Novartis Investigative Site Active, not recruiting
Nottingham, United Kingdom, NG5 1PB
Novartis Investigative Site Active, not recruiting
Sheffield, United Kingdom, S5 7AU
Novartis Investigative Site Active, not recruiting
Swindon, United Kingdom, SN3 6BB
Novartis Investigative Site Active, not recruiting
Wiltshire, United Kingdom, SN15 2SB
Novartis Investigative Site Active, not recruiting
Wrexham, United Kingdom, LL13 7TD
Sponsors and Collaborators
Novartis Pharmaceuticals
Investigators
Study Director: Novartis Pharmaceuticals Novartis Pharmaceuticals
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Novartis Pharmaceuticals
ClinicalTrials.gov Identifier: NCT01920711     History of Changes
Other Study ID Numbers: CLCZ696D2301
2013-001747-31 ( EudraCT Number )
Study First Received: August 8, 2013
Last Updated: March 7, 2017

Keywords provided by Novartis:
Heart failure, preserved ejection fraction, diastolic heart failure

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases
Valsartan
LCZ 696
Antihypertensive Agents
Angiotensin II Type 1 Receptor Blockers
Angiotensin Receptor Antagonists
Molecular Mechanisms of Pharmacological Action

ClinicalTrials.gov processed this record on March 29, 2017