IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients
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ClinicalTrials.gov Identifier: NCT01886456 |
Recruitment Status
: Unknown
Verified June 2013 by University of Zurich.
Recruitment status was: Recruiting
First Posted
: June 25, 2013
Last Update Posted
: June 25, 2013
|
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To investigate the effect of patterned laser trabeculoplasty (PLT) compared to selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) in treatment naiv patients suffering from open-angle glaucoma or ocular hypertension.
Values for IOP will be measured at baseline, 1 day and 1 month post-interventional as well as 2, 3, 6, 9, 12, 18 and 24 months after treatment.
- Trial with medical device
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Open Angle Glaucoma, Ocular Hypertension | Device: Laser trabeculoplasty | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 210 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Effect of Patterned Laser Trabeculoplasty on Intraocular Pressure Compared to Selective Laser Trabeculoplasty in Treatment Naiv Patients Suffering From Open-angle Glaucoma or Ocular Hypertension |
Study Start Date : | February 2013 |
Estimated Primary Completion Date : | February 2017 |
Estimated Study Completion Date : | February 2017 |

Arm | Intervention/treatment |
---|---|
Experimental: PLT
patients treated with patterned laser trabeculoplasty
|
Device: Laser trabeculoplasty |
Active Comparator: SLT
patients treated with selective laser trabeculoplasty
|
Device: Laser trabeculoplasty |
- Intraocular pressure 6 months after Intervention [ Time Frame: 6 months ]

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion criteria:
- Intraocular pressure (treatment naiv or after 4 weeks wash-out phase) > 21 mm Hg
- visible angle structures over 360° on gonioscopy
- age = 18 years
Exclusion criteria:
- Intraocular Inflammation
- patients who underwent refractive corneal surgery for any reason or who underwent ocular surgery to reduce intraocular pressure (e.g. trabeculectomy)
- monocle situation
- anterior chamber lenses (incl. iris claw)
- secondary glaucoma (with the exception of pseudoexfoliation and pigment dispersion)

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01886456
Contact: Gregor Jaggi, MD | gregor.jaggi@usz.ch | ||
Contact: Christoph Kniestedt, MD | christoph.kniestedt@usz.ch |
Switzerland | |
University Hospital Zurich, Ophthalmology Clinic | Recruiting |
Zurich, ZH, Switzerland, 8091 |
Principal Investigator: | Christoph Kniestedt, MD | University Hospital Zurich, Ophthalmology Clinic |
Responsible Party: | University of Zurich |
ClinicalTrials.gov Identifier: | NCT01886456 History of Changes |
Other Study ID Numbers: |
14.1.2013_KEK ZH 2012-0422 |
First Posted: | June 25, 2013 Key Record Dates |
Last Update Posted: | June 25, 2013 |
Last Verified: | June 2013 |
Additional relevant MeSH terms:
Hypertension Glaucoma Glaucoma, Open-Angle Ocular Hypertension |
Vascular Diseases Cardiovascular Diseases Eye Diseases |