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Study Of Diabetic Nephropathy With Atrasentan (SONAR)

This study is ongoing, but not recruiting participants.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01858532
First Posted: May 21, 2013
Last Update Posted: October 24, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
AbbVie
  Purpose
This study is being conducted to evaluate the effects of Atrasentan on Renal Outcomes in Subjects with Type 2 Diabetes and Nephropathy.

Condition Intervention Phase
Diabetic Nephropathy Drug: Atrasentan Drug: Placebo Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: A Randomized, Multicountry, Multicenter, Double-Blind, Parallel, Placebo-Controlled Study of the Effects of Atrasentan on Renal Outcomes in Subjects With Type 2 Diabetes and Nephropathy SONAR: Study Of Diabetic Nephropathy With Atrasentan

Resource links provided by NLM:


Further study details as provided by AbbVie:

Primary Outcome Measures:
  • Time to the first occurrence of a component of the composite renal endpoint. [ Time Frame: Approximately 48 months. ]
    Time to the first occurrence of a component of the composite renal endpoint: doubling of serum creatinine (confirmed by a 30-day serum creatinine) or the onset of end stage renal disease (estimated glomerular filtration rate (eGFR) less than 15 ml/min/1.73 m2 confirmed by a 90-day eGFR, receiving chronic dialysis, renal transplantation or renal death).


Secondary Outcome Measures:
  • Time to a 50% estimated glomerular filtration rate reduction. [ Time Frame: Approximately 48 months. ]
  • Time to cardio-renal composite endpoint: confirmed doubling of serum creatinine, end stage renal disease, cardiovascular death, nonfatal myocardial infarction, nonfatal stroke. [ Time Frame: Approximately 48 months. ]
  • Time to the cardiovascular composite endpoint: cardiovascular death, nonfatal myocardial infarction and nonfatal stroke. [ Time Frame: Approximately 48 months. ]
  • Time to first occurrence of a component of composite renal endpoint: confirmed doubling of serum creatinine or the onset of end stage renal disease for all randomized subjects (pooled). [ Time Frame: Approximately 48 months. ]

Enrollment: 3667
Study Start Date: May 17, 2013
Estimated Study Completion Date: April 8, 2020
Estimated Primary Completion Date: July 31, 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Atrasentan
Subjects randomized to the atrasentan arm will receive active drug, atrasentan.
Drug: Atrasentan
Oral daily low dose for 48 months.
Placebo Comparator: Placebo
Subjects randomized to the placebo arm will receive placebo.
Drug: Placebo
Oral daily dosing for 48 months.

Detailed Description:
The study objective is to evaluate the effect of atrasentan compared with placebo on time to doubling of serum creatinine or the onset of end stage renal disease (ESRD) in subjects with type 2 diabetes and nephropathy who are treated with the maximum tolerated labeled daily dose (MTLDD) of a Renin Angiotensin System (RAS) inhibitor. In addition, the study will assess the effects of atrasentan compared with placebo on cardiovascular morbidity and mortality, urine albumin excretion, changes in estimated glomerular filtration rate (eGFR), as well as on the impact on quality of life in subjects with type 2 diabetes and nephropathy.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Subject has type 2 diabetes (including patients with latent autoimmune diabetes or insulin-treated patients without a history of diabetic ketoacidosis who also have a negative anti-glutamic acid decarboxylase test AND an elevated post-prandial serum C-peptide level) and has been treated with at least one anti-hyperglycemic medication and ACEi/or ARB (RAS inhibitor) for at least 4 weeks prior to the Screening S2 visit.
  • For entry into the Run-In Period the subject must satisfy the following criteria based on the Screening laboratory values:

    • Estimated glomerular filtration rate (eGFR) 25 to 75 mL/min/1.73 m2 [until the eGFR cap on subjects (approximately 300) with a baseline of > 60 mL/min/1.73 m2 is reached] and a urine albumin creatinine ratio (UACR) greater than or equal to 300 and less than 5,000 mg/g (greater than or equal to 34 mg/mmol and less than 565 mg/mmol);
    • Serum albumin greater than or equal to 2.5 g/dL (25 g/L);
    • Brain natriuretic peptide (BNP) less than or equal to 200 pg/mL (200 ng/L);
    • Systolic blood pressure (SBP) greater than or equal to 110 and less than or equal to 180 mmHg;
    • Serum Potassium greater than or equal to 3.5 mEq/L (3.5 mmol/L) and less than or equal to 6.0 mEq/L (6.0 mmol/L);
    • Subjects on a maximum tolerated labeled daily dose (MTLDD) of a RAS inhibitor for greater than or equal to 4 weeks and on a diuretic at the time of screening and who satisfy the above criteria may proceed to the last visit in Run-In Period (R6);
    • Subjects already on a MTLDD of a RAS inhibitor for greater than or equal to 4 weeks and not on a diuretic (unless medically contraindicated) at the time of Screening will start with a diuretic and proceed to Run-In for at least 2 weeks.
  • For entry into the Enrichment Period the subject must satisfy the following criteria based on the last visit of the Run-In Period:

    • RAS inhibitor at the MTLDD for the previous 4 weeks with no adjustments of the dose;
    • Subjects that were on a MTLDD RAS inhibitor and not on a diuretic (unless medically contraindicated) at the time of Screening must have been in Run-In for at least 2 weeks.
  • For entry into the Double-Blind Treatment Period, the subject must satisfy the following criteria based on the last visit of the Enrichment Period:

    • RAS inhibitor at the MTLDD for the previous 6 weeks during the Enrichment Period with no adjustments of the dose;
    • Diuretic at any dose unless medically contraindicated or clinically intolerable in the investigator's judgement (i.e., hypotension or hypokalemia);
    • Subject must not have a weight change greater than or equal to 3 kg from the beginning of Enrichment to the end of the Enrichment Period and absolute serum BNP greater than or equal to 300 pg/mL (300 ng/L) at the last Enrichment visit;
    • Subject must not have an increase in serum creatinine greater than 0.5 mg/dL and greater than 20% increase from the beginning of Enrichment to the end of the Enrichment Period.

Exclusion Criteria:

  • Subject has a history of severe peripheral edema or facial edema requiring diuretics unrelated to trauma or a history of myxedema in the prior 4 weeks to the initial Screening S1 visit.
  • Subject has a history of pulmonary hypertension, pulmonary fibrosis or any lung diseases requiring oxygen therapy (e.g., chronic obstructive pulmonary disease, emphysema).
  • Subject has a documented diagnosis of heart failure, previous hospitalization for heart failure or current or constellation of symptoms (dyspnea on exertion, pedal edema, orthopnea, paroxysmal nocturnal dyspnea) felt to be compatible with heart failure, that was not explained by other causes, and for which there was a change in medication or other management directed at heart failure.
  • Subject has known non-diabetic kidney disease (other than kidney stones).
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01858532


  Hide Study Locations
Locations
United States, Alabama
Nephrology Associates P.C. /ID# 105317
Birmingham, Alabama, United States, 35211
University of Alabama at Birmingham (UAB) /ID# 140977
Birmingham, Alabama, United States, 35294
Nephrology Consultants, LLC /ID# 149462
Huntsville, Alabama, United States, 35805
Alabama Medical Group, PC /ID# 142835
Mobile, Alabama, United States, 36608
United States, Arizona
AKDHC Medical Research Services, LLC /ID# 106300
Peoria, Arizona, United States, 85381
Phoenix VA Healthcare System /ID# 149465
Phoenix, Arizona, United States, 85012
Arizona Kidney Disease and Hypertension Center /ID# 107196
Phoenix, Arizona, United States, 85027
AKDHC Medical Research Services, LLC /ID# 118549
Prescott, Arizona, United States, 86301
AKDHC Medical Research Services, LLC /ID# 110376
Tucson, Arizona, United States, 85718
Southern Arizona VA Health Care Systems /ID# 121160
Tucson, Arizona, United States, 85723
University of Arizona /ID# 153960
Tucson, Arizona, United States, 85724
United States, Arkansas
B.G. Clinical Research Center, LLC /ID# 107678
Little Rock, Arkansas, United States, 72205
United States, California
Dr. Lakhi M. Sakhrani, Alhambra, CA. /ID# 99948
Alhambra, California, United States, 91801
North America Research Institute /ID# 96605
Azusa, California, United States, 91702
National Institute of Clinical Research /ID# 114816
Bakersfield, California, United States, 93309
California Institute of Renal Research /ID# 96591
Chula Vista, California, United States, 91910
San Diego Coastal Endocrinology Group, aMC /ID# 99975
Chula Vista, California, United States, 91910
Dr. Ambrose Y. Tsang, Downey, CA /ID# 105566
Downey, California, United States, 90241
Rancho Los Amigos National Rehabilitation Center /ID# 147127
Downey, California, United States, 90242
St. Jude Hospital /ID# 101476
Fullerton, California, United States, 92835
California Renal Research Network, LLC /ID# 118555
Glendale, California, United States, 91204
California Institute of Renal Research /ID# 96597
La Mesa, California, United States, 91942
VA Loma Linda Healthcare System /ID# 148928
Loma Linda, California, United States, 92357
VA Long Beach Healthcare System /ID# 123260
Long Beach, California, United States, 90822
Academic Medical Research Institute /ID# 96596
Los Angeles, California, United States, 90022
UCLA /Id# 145915
Los Angeles, California, United States, 90025
Axis Clinical Trials /ID# 99397
Los Angeles, California, United States, 90036
National Research Institute /ID# 104915
Los Angeles, California, United States, 90057
Facey Medical Foundation /ID# 96704
Mission Hills, California, United States, 91345
Providence Clinical Research /ID# 102095
North Hollywood, California, United States, 91606
Lucita M. Cruz MD /ID# 105199
Norwalk, California, United States, 90650
Diabetes Associates Medical Group /ID# 107200
Orange, California, United States, 92868
Desert Medical Group, Inc. /ID# 96702
Palm Springs, California, United States, 92262
Mohammed Ismail, MD, Inc. /ID# 110415
Paramount, California, United States, 90723
Sierra View Nephrology Inc /ID# 105576
Porterville, California, United States, 93257
Inland Empire Liver Foundation /ID# 144258
Rialto, California, United States, 92377
APEX Research of Riverside /ID# 107455
Riverside, California, United States, 92505
Capital Nephrology Medical Group /ID# 104900
Sacramento, California, United States, 95825
Central Coast Nephrology /ID# 144669
Salinas, California, United States, 93901
California Institute of Renal Research /ID# 105316
San Diego, California, United States, 92111
Veterans Affairs San Diego Healthcare System /ID# 139970
San Diego, California, United States, 92161
North America Research Institute /ID# 101579
San Dimas, California, United States, 91773
San Francisco General Hospital/UCSF /ID# 105439
San Francisco, California, United States, 94110
Sansum Clinic /ID# 96640
Santa Barbara, California, United States, 93110
United States, Colorado
Denver Nephrologists, PC dba Colorado Kidney Care, PC /ID# 149164
Denver, Colorado, United States, 80218
United States, Connecticut
Yale University /ID# 111219
New Haven, Connecticut, United States, 06520-8029
Stamford Nephrology /ID# 104911
Stamford, Connecticut, United States, 06902
United States, Delaware
Christiana Care Health Services, Inc. /ID# 106297
Newark, Delaware, United States, 19713
United States, District of Columbia
George Washington University Medical Faculty Associates /ID# 96707
Washington, D.C., District of Columbia, United States, 20037
United States, Florida
ZASA Clinical Research /ID# 144058
Boynton Beach, Florida, United States, 33472
Meridien Research Group /ID# 116155
Bradenton, Florida, United States, 34208
Clinical Research of Brandon, LLC /ID# 121136
Brandon, Florida, United States, 33511
South Florida Nephrology Group, PA /ID# 105438
Coral Springs, Florida, United States, 33071
Lee County Internal Medicine Associates /ID# 105315
Fort Myers, Florida, United States, 33912
University of Florida /ID# 118546
Gainesville, Florida, United States, 32609
Pines Clinical Research, Inc. /ID# 96623
Hollywood, Florida, United States, 33024
FPA Family Health Care Clinical Studies /ID# 99897
Kissimmee, Florida, United States, 34741
West Broward Research Institute, LLC /ID# 147125
Lauderdale Lakes, Florida, United States, 33313
San Marcus Research Clinic, Inc. /ID# 111220
Miami, Florida, United States, 33015
Premier Clinical Research Institute, Inc. /ID# 118315
Miami, Florida, United States, 33122
Premier Research Associate, Inc /ID# 116195
Miami, Florida, United States, 33165
Innovative Medical Research of South Florida, Inc. /ID# 117452
North Miami Beach, Florida, United States, 33169
Compass Research LLC /ID# 111221
Orlando, Florida, United States, 32806
Ribo Research, LLC dba Peninsula Research /ID# 120275
Ormond Beach, Florida, United States, 32174
Nephrology Associates Research Center /ID# 116895
Panama City, Florida, United States, 32401
Pines Care Research Center, Inc. /ID# 111223
Pembroke Pines, Florida, United States, 33026
Hanson Clinical Research Center /ID# 105436
Port Charlotte, Florida, United States, 33952
Central Florida Internists /ID# 105196
Saint Cloud, Florida, United States, 34741
Professional Health Care of Pinellas /ID# 118760
Saint Petersburg, Florida, United States, 33713
James A. Haley Veteran's Hospital /ID# 121157
Tampa, Florida, United States, 33612
Metabolic Research Institute, Inc. /ID# 96606
West Palm Beach, Florida, United States, 33401
United States, Georgia
Emory University Hospital /ID# 101578
Atlanta, Georgia, United States, 30322
Augusta University /ID# 114938
Augusta, Georgia, United States, 30912
Atlanta Nephrology Referral Center /ID# 107999
Decatur, Georgia, United States, 30030
Emory University and Atlanta VA Medical Center /ID# 121776
Decatur, Georgia, United States, 30033
Kaiser Foundation Health Plan of Georgia, Inc. /ID# 107960
Duluth, Georgia, United States, 30096
Alta Pharmaceutical Research Center, Inc. /ID# 105177
Dunwoody, Georgia, United States, 30338
Gwinnett Biomedical Research /ID# 99945
Lawrenceville, Georgia, United States, 30046
Herman Clinical Research, LLC /ID# 105155
Suwanee, Georgia, United States, 30024
United States, Hawaii
University of Hawaii /ID# 99596
Honolulu, Hawaii, United States, 96813
East West Medical Research Institute /ID# 96598
Honolulu, Hawaii, United States, 96814
United States, Illinois
Jesse Brown VA Medical Center /ID# 121777
Chicago, Illinois, United States, 60612
Apex Medical Research, Inc. /ID# 96588
Chicago, Illinois, United States, 60616
The University of Chicago Medical Center /ID# 101577
Chicago, Illinois, United States, 60637
NorthShore University HealthSystem /ID# 117095
Evanston, Illinois, United States, 60201
Kidney Care Center /ID# 114936
Joliet, Illinois, United States, 60435
United States, Indiana
Community Clinical Research Center /ID# 111215
Anderson, Indiana, United States, 46011
Nephrology Associates of Northern Indiana/Illinois /ID# 149541
Fort Wayne, Indiana, United States, 46084
United States, Iowa
Iowa Diabetes and Endocrinology Research Center /ID# 105297
Des Moines, Iowa, United States, 50314
University of Iowa Hospitals and Clinics /ID# 107677
Iowa City, Iowa, United States, 52242
United States, Kansas
My Kidney Center, LLC /ID# 104904
Manhattan, Kansas, United States, 66502
United States, Kentucky
Four Rivers Clinical Research, Inc. /ID# 110456
Paducah, Kentucky, United States, 42003
United States, Louisiana
Ochsner Clinic Foundation /ID# 111225
Baton Rouge, Louisiana, United States, 70809
Crescent City Clinical Research Center, LLC /ID# 112921
Metairie, Louisiana, United States, 70006
Louisiana State University Health Sciences Center /ID# 104135
New Orleans, Louisiana, United States, 70112
Tulane University /ID# 96617
New Orleans, Louisiana, United States, 70112
Internal Medicine Specialists /ID# 110457
New Orleans, Louisiana, United States, 70115
Green Clinic LLC /ID# 100456
Ruston, Louisiana, United States, 71270
United States, Maine
Maine Research Associates /ID# 110377
Auburn, Maine, United States, 04210
United States, Maryland
Model Clinical Research /ID# 96610
Baltimore, Maryland, United States, 21204
Biolab Research, LLC /ID# 96590
Rockville, Maryland, United States, 20852
Washington Nephrology Associates /ID# 150111
Takoma Park, Maryland, United States, 20912
United States, Massachusetts
Pentucket Medical Associates, LLC /ID# 112919
Haverhill, Massachusetts, United States, 01830
ActivMed Practices and Research, Inc. /ID# 147124
Methuen, Massachusetts, United States, 01844
Pentucket Medical Associates, LLC /ID# 121158
Newburyport, Massachusetts, United States, 01950
South Shore Nephrology, P.C. /ID# 99946
Plymouth, Massachusetts, United States, 02360
United States, Michigan
Renaissance Renal Research Institute, LLC /ID# 114838
Detroit, Michigan, United States, 48236
Hurley Medical Center /ID# 96613
Flint, Michigan, United States, 48503
Apex Medical Research, MI,Inc. /ID# 105176
Flint, Michigan, United States, 48504
Remedica LLC /ID# 105198
Rochester, Michigan, United States, 48307
United States, Mississippi
Southwest Mississippi Nephrology, PLLC /ID# 107957
Brookhaven, Mississippi, United States, 39601
University of Mississippi Medical Center /ID# 104895
Jackson, Mississippi, United States, 39216
United States, Missouri
Harry S. Truman Memorial Veteran's Hospital /ID# 122116
Columbia, Missouri, United States, 65201-5297
Farmington Research LLC /ID# 96589
Farmington, Missouri, United States, 63640
Clinical Research Consultants, LLC /ID# 141014
Kansas City, Missouri, United States, 64111
Kansas City VA Medical Center /ID# 129801
Kansas City, Missouri, United States, 64128
VA Saint Louis Health Care System /ID# 143803
Saint Louis, Missouri, United States, 63106
United States, Nebraska
Creighton University Medical Center /ID# 96616
Omaha, Nebraska, United States, 68131
United States, Nevada
Nevada Kidney Disease and Hypertension Center aka NKDHC /ID# 112900
Las Vegas, Nevada, United States, 89115
Palm Research Center, Inc. /ID# 105501
Las Vegas, Nevada, United States, 89148
Sierra Nevada Nephrology Consultants /ID# 104910
Reno, Nevada, United States, 89511
United States, New Hampshire
Seacoast Kidney and Hypertension Specialists, PLLC /ID# 105444
Portsmouth, New Hampshire, United States, 03801
United States, New Jersey
Cooper Nephrology /ID# 105075
Camden, New Jersey, United States, 08103
Hypertension and Nephrology Associates PA /ID# 103995
Eatontown, New Jersey, United States, 07724
Jersey Shore University Medical Center /ID# 104905
Neptune City, New Jersey, United States, 07753
United States, New Mexico
Renal Medicine Associates /ID# 106276
Albuquerque, New Mexico, United States, 87109
University of New Mexico /ID# 107675
Albuquerque, New Mexico, United States, 87109
High Desert Nephrology Associates /Id# 149468
Gallup, New Mexico, United States, 87301
United States, New York
Albany Medical College /ID# 96592
Albany, New York, United States, 12206
SUNY Downstate Medical Center, Univ Hosp Brooklyn /ID# 112903
Brooklyn, New York, United States, 11203
Dr. Marie Bentsianov, Brooklyn, NY /ID# 111216
Brooklyn, New York, United States, 11224
Ezra Israel, MD, Brooklyn, NY /ID# 116196
Brooklyn, New York, United States, 11229
Erie County Medical Center /ID# 112897
Buffalo, New York, United States, 14215
North Shore Diabetes and Endocrine Associates /ID# 96604
New Hyde Park, New York, United States, 11042
Dr. Albert DeFabritus, New York, NY /ID# 107215
New York, New York, United States, 10001
VA NY Harbor Healthcare System ACOS for Ambulatory Care(11A) /ID# 124478
New York, New York, United States, 10010
NYU Langone Medical Center /ID# 106302
New York, New York, United States, 10016
NY Clinical Trials /ID# 112896
New York, New York, United States, 10018
Kaufman, New York, NY /ID# 105235
New York, New York, United States, 10021
Rogosin Institute /ID# 106835
New York, New York, United States, 10021
Hypertension and Renal Research Group /ID# 96603
Orchard Park, New York, United States, 14127
Clinical Research Development Associates, LLC /ID# 104137
Rosedale, New York, United States, 11422
Ladan Golestaneh, MD, MS /ID# 110375
The Bronx, New York, United States, 10467
United States, North Carolina
Mountain Kidney Research and Hypertension Associates, PA /ID# 148930
Asheville, North Carolina, United States, 28801
Metrolina Nephrology Associates, PA /ID# 96638
Charlotte, North Carolina, United States, 28207
Sensenbrenner Primary Care, Charlotte, NC /ID# 112918
Charlotte, North Carolina, United States, 28277
East Carolina University Nephrology Research /ID# 104901
Greenville, North Carolina, United States, 27834
Eastern Nephrology Associates /ID# 144913
Greenville, North Carolina, United States, 27834
Eastern Nephrology Associates /ID# 105441
Kinston, North Carolina, United States, 28504
Carteret Medical Group /ID# 99898
Morehead City, North Carolina, United States, 28557
Eastern Nephrology Associates, PLCC /ID# 100876
New Bern, North Carolina, United States, 28562
Boice-Willis Clinic, P.A. /ID# 104903
Rocky Mount, North Carolina, United States, 27804
W.G. (Bill) Hefner VAMC /ID# 147761
Salisbury, North Carolina, United States, 28144
Brookview Hills Research Associates, LLC /ID# 96602
Winston-Salem, North Carolina, United States, 27103
United States, Ohio
VAMC Cincinnati /ID# 121159
Cincinnati, Ohio, United States, 45220
University of Cincinnati Physicians /ID# 99943
Cincinnati, Ohio, United States, 45267-0585
MetroHealth Medical Center /ID# 96708
Cleveland, Ohio, United States, 44109
Cleveland Clinic Foundation /ID# 111224
Cleveland, Ohio, United States, 44195
Endocrinology Associates, Inc. /ID# 103997
Columbus, Ohio, United States, 43201
United States, Oklahoma
Harold Hamm Diabetes Center /ID# 141936
Oklahoma City, Oklahoma, United States, 73104
United States, Oregon
Oregon Health & Science University (OHSU) /ID# 105458
Portland, Oregon, United States, 97239
United States, Pennsylvania
Northeast Clinical Research Centers, LLC /ID# 96607
Bethlehem, Pennsylvania, United States, 18017
Penn State Univ and Milton S. Hershey Medical Center /ID# 107198
Hershey, Pennsylvania, United States, 17033
Drexel University College of Medicine /ID# 107195
Philadelphia, Pennsylvania, United States, 19102
Thomas Jefferson University Hospital /ID# 106275
Philadelphia, Pennsylvania, United States, 19107
Temple University Hospital /ID# 107715
Philadelphia, Pennsylvania, United States, 19140
Philadelphia Health Associates-Adult Medicine, PC /ID# 111226
Philadelphia, Pennsylvania, United States, 19146
VA Pittsburgh Healthcare System /ID# 121139
Pittsburgh, Pennsylvania, United States, 15240
Preferred Primary Care Physicians, Inc /ID# 105516
Pittsburgh, Pennsylvania, United States, 15243
United States, Rhode Island
Rhode Island Hospital /ID# 99396
Providence, Rhode Island, United States, 02903
United States, South Carolina
Columbia Nephrology Associates, PA /ID# 105175
Columbia, South Carolina, United States, 29203
WJB Dorn Va Medical Center /ID# 144830
Columbia, South Carolina, United States, 29209
Carolina Health Specialists /ID# 107197
Myrtle Beach, South Carolina, United States, 29572
South Carolina Nephrology and Hypertension Center, Inc. /ID# 96612
Orangeburg, South Carolina, United States, 29118
United States, Tennessee
southeast Renal Research Institute /ID# 96620
Chattanooga, Tennessee, United States, 37408
Advanced Kidney Specialists Pc /Id# 106301
Jackson, Tennessee, United States, 38305
Knoxville Kidney Center, PLLC /ID# 105200
Knoxville, Tennessee, United States, 37923
University of Tennessee Health Sciences Center /ID# 103015
Memphis, Tennessee, United States, 38163
United States, Texas
DCT - MHR, LLC dba Discovery Clinical Trials /ID# 144098
Arlington, Texas, United States, 76014
Dr. Osvaldo A. Brusco, Corpus Christi, TX /ID# 99976
Corpus Christi, Texas, United States, 78414
Houston Nephrology Group /ID# 105336
Cypress, Texas, United States, 77429
Texas Health Physicians Group /ID# 105600
Dallas, Texas, United States, 75218
North Texas Endocrine Center /ID# 107955
Dallas, Texas, United States, 75231
Renal Research Institute /ID# 148932
Dallas, Texas, United States, 75246-1791
Dr. Odilon P. Alvarado, Fort Worth, TX /ID# 105159
Fort Worth, Texas, United States, 76104
Texas Renal Care /ID# 111222
Greenville, Texas, United States, 75402
Diagnostic Clinic Of Houston /ID# 105575
Houston, Texas, United States, 77004
Diagnostic Clinic Of Houston /ID# 113455
Houston, Texas, United States, 77004
Endocrine Associates /ID# 99896
Houston, Texas, United States, 77004
Kidney and Hypertension Care Center /ID# 114937
Houston, Texas, United States, 77004
JM Research /ID# 138104
Houston, Texas, United States, 77011
PrimeCare Medical Group /ID# 100455
Houston, Texas, United States, 77024
Angiocardiac Care of Texas, PA /ID# 112901
Houston, Texas, United States, 77025
Southwest Houston Nephrology and Hypertension Clinic /ID# 112917
Houston, Texas, United States, 77074
Texas Tech University Health Sciences Center /ID# 96705
Lubbock, Texas, United States, 79430
East Texas Nephrology Associates /ID# 106815
Lufkin, Texas, United States, 75904
Texas Institute for Kidney & Endocrine Disorders /ID# 138102
Lufkin, Texas, United States, 75904
DCT - McAllen Primary Care Research, LLC dba DCT /ID# 144260
McAllen, Texas, United States, 78503
South Texas Kidney Specialists, PA /ID# 96608
McAllen, Texas, United States, 78503
Independent Clinical Research /ID# 111217
McKinney, Texas, United States, 75069
Clinical Advancement Center, PLLC /ID# 96615
San Antonio, Texas, United States, 78215
Briggs Clinical Research, LLC /ID# 104913
San Antonio, Texas, United States, 78224
Audie L. Murphy VA Medical Center, STVHCS /ID# 121138
San Antonio, Texas, United States, 78229
San Antonio Kidney Disease Center Physicians Group, PLLC /ID# 109416
San Antonio, Texas, United States, 78229
Univ of Texas Health Science Center San Antonio /ID# 107535
San Antonio, Texas, United States, 78229
Kidney Innovations /ID# 114817
Weslaco, Texas, United States, 78596
United States, Utah
Advanced Research Institute /ID# 105157
Ogden, Utah, United States, 84405
Southern Utah Kidney and Hypertension Center /ID# 118547
Saint George, Utah, United States, 84790
University of Utah /ID# 105178
Salt Lake City, Utah, United States, 84108
United States, Vermont
Fletcher Allen Health Care, Inc. /ID# 107376
Burlington, Vermont, United States, 05401
VA Medical Center /ID# 141590
White River Junction, Vermont, United States, 05009
United States, Virginia
Nephrology Associates of Northern Virginia, Inc. /ID# 105202
Fairfax, Virginia, United States, 22033
McGuire VA Medical Center /ID# 148934
Richmond, Virginia, United States, 23249
Salem Veterans Affairs Medical Center /ID# 123302
Salem, Virginia, United States, 24153
United States, Washington
Northside Internal Medicine DEXA /ID# 107959
Spokane, Washington, United States, 99207
MultiCare Institute for Research and Innovation /ID# 103695
Tacoma, Washington, United States, 98405
United States, West Virginia
West Virginia University, School of Medicine /ID# 105201
Morgantown, West Virginia, United States, 26506-9165
United States, Wisconsin
Marshfield Clinic - Marshfield Center /ID# 144670
Marshfield, Wisconsin, United States, 54449
Zablocki VA Medical Center /ID# 122757
Milwaukee, Wisconsin, United States, 53295
Argentina
Instituto de Investigaciones Clinicas Bahia Blanca /ID# 104796
Bahia Blanca, Argentina, B8000FTD
Instituto de Investigaciones Medicas Alfredo Lanari /ID# 100537
Buenos Aires, Argentina, 1427
Hospital Italiano de Buenos Aires /ID# 105056
Buenos Aires, Argentina, C1199ABB
Consultorios Asociados de Endocrinologia / Inv Clin Aplicado /ID# 100895
Buenos Aires, Argentina, C1425AGC
Centro de Educacion Medica e Investigaciones Clinicas /ID# 106256
Buenos Aires, Argentina, C1431FWO
Instituto Latinoamericano de Investigaciones Medicas /ID# 104776
Cordoba, Argentina, X5000BNB
Blossom DMO /ID# 107357
Cordoba, Argentina, X5000JHA
Fundacion J. Robert Cade /ID# 105520
Cordoba, Argentina, X5002HWE
Hospital Privado Centro Medico de Cordoba /ID# 104795
Cordoba, Argentina
Instituto Cardiologia de Corrientes Juana Francisca Cabral /ID# 100535
Corrientes, Argentina, 3400
Centro de Salud Renal Junin S.R.L. /ID# 100536
Junin, Argentina, B6000GPB
Centro de Investigaciones Medicas Mar del Plata /ID# 106255
Mar del Plata, Argentina, B7600FYK
Instituto de Nefrologia Pergamino S.R.L. /ID# 105057
Pergamino, Argentina, B2700CPM
Investigaciones Clinicas Tucuman /ID# 104775
San Miguel de Tucuman, Argentina, 4000
Cereha /Id# 107356
Sarandi, Argentina, 1872
Australia
Box Hill Hospital /ID# 104800
Box Hill, Australia, 3128
Royal Prince Alfred Hospital /ID# 119395
Camperdown, Australia, 2050
Concord Repatriation and General Hospital /ID# 109575
Concord, Australia, 2139
Southern Adelaide Diabetes Endocrine Services /ID# 104736
Daw Park, Australia, 5041
St. Vincents Hospital Melbourne /ID# 110515
Fitzroy, Australia, 3065
Fremantle Hospital /ID# 110535
Fremantle, Australia, 6160
Renal Research /ID# 102598
Gosford, Australia, 2250
Launceston General Hospital /ID# 113775
Launceston, Australia, 7250
Liverpool Hospital /ID# 102596
Liverpool, Australia, 2170
Nambour General Hospital /ID# 103675
Nambour, Australia, 4560
Sir Charles Gairdner Hospital /ID# 104797
Nedlands, Australia, 6009
John Hunter Hospital /ID# 107756
New Lambton Heights, Australia, 2305
Royal Melbourne Hospital /ID# 109577
Parkville, Australia, 3052
The Prince of Wales Hospital /ID# 114235
Randwick, Australia, 2031
Royal North Shore Hospital /ID# 104735
St Leonards, Australia, 2065
Austria
Medical University of Innsbruck /ID# 118178
Innsbruck, Austria, 6020
AKH - Medizinische Universität Vienna /ID# 118736
Vienna, Austria, 1090
AKH - Medizinische Universität Vienna /ID# 118737
Vienna, Austria, 1090
Krankenhaus Hietzing /ID# 116675
Vienna, Austria, 1130
Belgium
Onze Lieve Vrouw Hospital /ID# 106756
Aalst, Belgium, 9300
Imelda Ziekenhuis /ID# 142489
Bonheiden, Belgium, 2820
CUB Hospital Erasme /ID# 106795
Brussels, Belgium, 1070
Cliniques Universitaires Saint-Luc /ID# 106755
Brussels, Belgium, 1200
Universitair Ziekenhuis Leuven /ID# 107482
Leuven, Belgium, 3000
CHR de la Citadelle /ID# 100315
Liege, Belgium, 4000
Brazil
Hospital Universitario Joao De Barros Barre /ID# 107939
Belem, Brazil, 66073-000
Hospital SOCOR /ID# 100877
Belo Horizonte, Brazil, CEP 30180-060
Centro de Pesquisa Clinica do Brasil /ID# 107479
Brasilia, Brazil, 71625-009
Cline Research Center /ID# 103976
Curitiba, Brazil, 80030-480
Instituto Scribner de Pesquisa /ID# 100539
Curitiba, Brazil, 80240-030
Clinica Senhor do Bonfim - CSB - Feira de Santana /ID# 141335
Feira de Santana, Brazil, 44001-465
Centro de Estudos em Diabetes e Hipertensao /ID# 105521
Fortaleza, Brazil, 60115-282
Hospital Geral de Goiania /ID# 104359
Goiania, Brazil, 74110010
Fundacao Pro Rim /ID# 102555
Joinville, Brazil, 89227-680
Hospital Universitario Cajuru /ID# 104361
Parana, Brazil, 80230-130
Hospital de Clinicas de Porto Alegre /ID# 103977
Porto Alegre, Brazil, 90035-003
Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 104358
Porto Alegre, Brazil, 90035-074
Centro de Pesquisa em Diabetes /ID# 102557
Porto Alegre, Brazil, 90035-170
Hospital Sao Lucas da PUCRS /ID# 101475
Porto Alegre, Brazil, 90610-000
Clinica Senhor do Bonfim - CSB - Salvador /ID# 141334
Salvador, Brazil, 40415-065
IPEC - Instituto de Pesquisa Clinica /ID# 104357
Sao Paulo, Brazil, 01223-001
CPQuali Pesquisa Clinica Ltda /ID# 143774
Sao Paulo, Brazil, 01228-000
Centro de Pesquisas Clinicas /ID# 100776
Sao Paulo, Brazil, 01244-030
Hospital Beneficencia Portuguesa de Sao Paulo /ID# 106258
Sao Paulo, Brazil, 01323-030
Instituto Dante Pazzanese de Cardiologia /ID# 108516
Sao Paulo, Brazil, 04012-180
University Federal de Sao Paulo /ID# 102136
Sao Paulo, Brazil, 04022-001
Hospital do Rim /ID# 104362
Sao Paulo, Brazil, 04025-011
University Federal de Sao Paulo /ID# 118235
Sao Paulo, Brazil, 04039-000
Servico de Endocrinologia- Divisao de Clinica Medica- Hospit /ID# 102135
Sao Paulo, Brazil, 05403-000
Clinica de Endocrinologia /ID# 100538
Sao_paulo, Brazil, 01322-000
Canada
LMC Diabetes and Endocrinology /ID# 103981
Brampton, Canada, L6S 0C9
JBN Medical Diagnostic Services Inc. /ID# 107875
Burlington, Canada, L7M 4Y1
Co-Medica Research Network, Inc /ID# 105676
Courtice, Canada, L1E 3C3
Toronto East General Medical Centre /ID# 100117
East York, Canada, M4C 5T2
Cross Cancer Institute, University of Alberta /ID# 109095
Edmonton, Canada, T6G 2B7
LMC Diabetes and Endocrinology /ID# 103982
Etobicoke, Canada, M9R 4E1
Centre de Sante et de Services Sociaux Champlain /ID# 101536
Greenfield Park, Canada, J4V 2H1
St. Joseph's Healthcare /ID# 113016
Hamilton, Canada, L8N 4A6
Clinical Research Solutions Inc. /ID# 99395
Kitchener, Canada, N2H 5Z8
Hospital Maisonneuve-Rosemont /ID# 101556
Montreal, Canada, H1T 2M4
CHUM - Hopital Saint-Luc /ID# 110475
Montreal, Canada, H2X 3J4
The Bailey Clinic /ID# 100155
Red Deer, Canada, T4N 6V7
OTT Healthcare Inc. /ID# 100115
Scarborough, Canada, M1H 3G4
Medicor Research Inc. /ID# 118543
Sudbury, Canada, P3E 1H5
LMC Diabetes and Endocrinology /ID# 104835
Toronto, Canada, M4G 3E8
Sunnybrook Health Sciences Centre /ID# 122482
Toronto, Canada, M4G 3E8
Humber River Hospital /ID# 107202
Toronto, Canada, M9N 1N8
Centre de Sante et de Services Sociaux de Trois Rivieres /ID# 122484
Trois-Rivieres, Canada, G8Z 3R9
St. Paul's Hospital /ID# 116975
Vancouver, Canada, V6Z 1Y6
Chile
Hospital Clinico Regional Dr. Guillermo Grant Benavente /ID# 105059
Concepcion, Chile
Calmed /Id# 100556
La Serena, Chile
Hospital del Salvador /ID# 105535
Providencia, Santiago, Chile, 750-0922
Biomedica Research Group /ID# 105058
Santiago, Chile, 7500710
Servicios Medicos Godoy Limitada /ID# 102175
Santiago, Chile, 7500710
Quantum Research Stgo. /ID# 148213
Santiago, Chile, 75500588
Centro de Investigacion Clinica del Sur (CICS) /ID# 100555
Temuco, Chile, 4781156
China
Peking Union Medical College Hospital /ID# 126728
Beijing, China, 100005
The 1st Hospital of Peking University /ID# 124715
Beijing, China, 100034
The 1st Hospital of Peking University /ID# 124716
Beijing, China, 100034
Peking University Peoples Hospital /ID# 123821
Beijing, China, 100044
Peking University Peoples Hospital /ID# 128059
Beijing, China, 100044
Peking University Third Hospital /ID# 127059
Beijing, China, 100191
Beijing Tongren Hospital /ID# 126452
Beijing, China, 100730
West China University Hospital, Sichuan University /ID# 126456
Chengdu, China, 610041
1st Affiliated Hospital of Third Military Med Univ PLA /ID# 126457
Chongqing, China, 400038
The Second Affiliated Hospital of Dalian Medical University /ID# 126463
Dalian, China, 116027
Foshan First People's Hospital of Foshan /ID# 126718
Foshan, China, 528000
The Third Affiliated Hospital of Sun Yat-sen University /ID# 128055
Guangzhou, Guangdong Province, China, 510630
Guangdong General Hospital /ID# 126727
Guangzhou, China, 510080
Nanfang Hospital of Southern Medical University /ID# 123817
Guangzhou, China, 510515
2nd Hospital of Hebei Med. University /ID# 126885
Hebei Province, China, 050000
Shandong Provincial Hospital /ID# 128255
Jinan, China, 250021
Zhongda Hospital, Southeast University /ID# 123816
Nanjing, China, 210009
Jiadngsu Province People's Hospital /ID# 123815
Nanjing, China, 210029
Ningbo No. 2 Hospital /ID# 150113
Ningbo City, Zhejiang Provienc, China, 315010
Affiliated Hospital of Medical College, Qingdao University /ID# 127520
Qingdao, China, 266003
Shanghai Changzheng Hospital /ID# 123818
Shanghai, China, 200003
Ruijin Hospital, Shanghai Jiaotong Univ, School of Medicine /ID# 123820
Shanghai, China, 200025
Zhongshan Hospital of Fudan University /ID# 124719
Shanghai, China, 200032
Huashan Hospital of Fudan University /ID# 124721
Shanghai, China, 200040
Renji Hospital, Shanghai Jiaotong University School of Med /ID# 123819
Shanghai, China, 200127
Shanghai 6th People`s Hospital /ID# 124722
Shanghai, China, 200233
Tongji Hospital of Tongji Medical College /ID# 124727
Wuhan, China, 430030
Renmin Hospital of Wuhan University /ID# 124726
Wuhan, China, 430060
The 1st Affil Hosp of 4th Military Med Univ PLA Xijing Hosp /ID# 124730
Xi'an, China, 710032
The 1st Affil Hosp of 4th Military Med Univ PLA Xijing Hosp /ID# 124731
Xi'an, China, 710032
The First Affiliated Hospital of Xi'an Jiaotong University /ID# 126717
Xi'an, China, 710061
The First Affiliated Hospital of Zhengzhou University /ID# 139216
Zhengzhou City, China, 450052
Czechia
Petr Bucek s.r.o. /ID# 108555
Frydek-Mistek, Czechia, 738 01
Masarykova mestska nemocnice /ID# 108556
Jilemnice, Czechia, 514 01
Hospital Novy Jicin a. s. /ID# 110816
Novy Jicin, Czechia, 74101
Fakultni nemocnice Ostrava /ID# 110817
Ostrava-Poruba, Czechia, 70852
Diabetologicka ambulance /ID# 103579
Pardubice, Czechia, 530 02
Fakultni Nemocnice Kralovske Vinohrady FNKV /ID# 110818
Prague 10, Czechia, 10034
Milan Kvapil s.r.o. /ID# 103575
Prague 4, Czechia, 149 00
Vseobecna fakultni nemocnice v Praze (VFN) /ID# 109715
Prague, Czechia, 12808
PeMedica.CZ, s.r.o. /ID# 103578
Prague, Czechia, 15500
Nemocnice Trebic /ID# 108557
Trebic, Czechia, 674 01
Dr. Emil Zahumensky, Valasske Klobouky, Czech Republic /ID# 108558
Valasske Klobouky, Czechia, 766 01
Denmark
Aarhus University Hospital, Skejby /ID# 106195
Aarhus, Denmark, 8200
University Hospital of Frederiskberg /ID# 103855
Frederiksberg, Denmark, 2000
Steno Diabetes Center /ID# 107459
Gentofte, Denmark, 2820
Regional Hospital Holstebro /ID# 104226
Holstebro, Denmark, 7500
Roskilde Hospital /ID# 103857
Rosklide, Denmark, 4000
Slagelse Hospital /ID# 101136
Slagelse, Denmark, 4200
Odense Universitets Hospital Svendborg Sygehus /ID# 106796
Svendborg, Denmark, 5700
Finland
Terveystalo Oulu /ID# 103858
Oulu, Finland, 90100
Tampere University Hospital /ID# 111895
Tampere, Finland, 33520
Turku University Hospital /ID# 125195
Turku, Finland, 20520
France
CHU de Bordeaux /ID# 107817
Bordeaux, France, 33076
Centre Hospitalier sud Francilien de Corbeil-Essonnes /ID# 106695
Corbeil-Essones, France, 91100
CHU de Grenoble - Hopital Albert Michallon /ID# 103896
Grenoble, France, 38042
Hopital de la Conception /ID# 103961
Marseille Cedex 5, France, 13385
CHU de Nice /ID# 112055
Nice, France, 06001
Hospital European, Georges Pompidou /ID# 103860
Paris, France, 75908
Centre Hospitalier Lyon Sud /ID# 103895
Pierre-Benite, France, 69495
Clinique du Landy /ID# 112056
Saint Ouen, France, 93400
Hopital Bretonneau - CHU Tours /ID# 117737
Tours, France, 37044
Germany
Universitaetsklinikum Aachen /ID# 112075
Aachen, Germany, 52074
Charite Campus Mitte /ID# 108416
Berlin, Germany, 10117
Klinische Forschung Berlin GbR /ID# 100562
Berlin, Germany, 10787
Universitaetklinikum Dresden /ID# 108415
Dresden, Germany, 01307
DaVita Clinical Research Deutschland GmbH /ID# 100559
Dusseldorf, Germany, 40210
Gemeinschaftspraxis Dialyse am Heidering, Hanover, Germany /ID# 114735
Hanover, Germany, 30625
St. Josefskrankenhaus /ID# 121575
Heidelberg, Germany, 69115
Nephrologisches Zentrum /ID# 125198
Hoyerswerda, Germany, 02977
Universitaetsklinikum Jena /ID# 103899
Jena, Germany, 07747
Ludwig Maximiliam Universitaet Muenchen /ID# 113915
Munich, Germany, 80336
Diabetologische Schwerpunktpraxis Pirna /ID# 125196
Pirna, Germany, 01796
Bieler, Riesa, DE /ID# 125197
Riesa, Germany, 01587
Diabetologische Schwerpunktpraxis /ID# 112076
Speyer, Germany, 67346
Robert-Bosch-Krankenhaus /ID# 112975
Stuttgart, Germany, 70376
Universitaetsklinikum Wuerzburg /ID# 108895
Wuerzburg, Germany, 97080
Greece
Dimokritio University Hospital of Alexandroupoli /ID# 100316
Alexandroupolis, Greece, 68100
General Hospital of Athens, Evangelismos /ID# 112015
Athens, Greece, 10676
General Hospital of Athens "Laiko" /ID# 140788
Athens, Greece, 11527
University General Hospital of Ioannina /ID# 109317
Ionnina, Greece, 45500
Sismanogleio General Hospital of Komotini /ID# 109535
Komotini, Greece, 69100
Regional General University Hospital of Larissa /ID# 107996
Larisa, Greece, 41100
University General Hospital of Patras /ID# 103963
Patras, Greece, 26504
University General Hospital "AHEPA" /ID# 107818
Thessaloniki, Greece, 54636
Interbalkan Medical Center /ID# 103962
Thessaloniki, Greece, 57001
Hong Kong
Prince of Wales Hospital /ID# 107755
Hong Kong SAR, Hong Kong
Queen Mary Hospital, Univ Hong Kong /ID# 110555
Hong Kong, Hong Kong
Tung Wah Hospital /ID# 129857
Hong Kong, Hong Kong
Princess Margaret Hospital /ID# 104817
Kowloon, Hong Kong
Queen Mary Hospital, Univ Hong Kong /ID# 103095
Pokfulam, Hong Kong, Hong Kong
Yan Chai Hospital /ID# 137267
Tsuen Wan, New Territories, Hong Kong
Our Lady Maryknoll Hospital /ID# 112122
Wong Tai Sin, Kowloon, Hong Kong
Ireland
Cork University Hospital /ID# 104075
Cork, Ireland
Connolly Hospital /ID# 111996
Dublin 15, Ireland
The Adelaide and Meath Hospital /ID# 111995
Dublin 24, Ireland
St Vincent's University Hospital /ID# 104236
Dublin 4, Ireland, D04 T6F4
University Hospital Limerick /ID# 106715
Limerick, Ireland, V95F858
Israel
Ha'Emek Medical Center /ID# 103938
Afula, Israel, 18101
Barzilai Medical Center /ID# 113376
Ashkelon, Israel, 78278
Carmel Medical Center /ID# 108219
Haifa, Israel, 3436212
Rambam Health Care Campus /ID# 118180
Haifa, Israel, 3525406
The Edith Wolfson Medical Center /ID# 113377
Holon, Israel, 58100
Shaare Zedek Medical Center /ID# 123616
Jerusalem, Israel, 91031
Meir Medical Center /ID# 114757
Kfar Saba, Israel, 44281
Kaplan Medical Center /ID# 132511
Rehovot, Israel, 76100
Maccabi Health Services /ID# 100318
Rishon Lezion, Israel, 7565016
DMC Diabetes Medical Center /ID# 150117
Tel Aviv, Israel, 61480
The Tel Aviv Sourasky MC /ID# 114756
Tel Aviv, Israel, 64239
Ziv Medical Center /ID# 103921
Zefat, Israel, 13100
Assaf Harofeh Medical Center /ID# 123615
Zerifin, Israel, 70300
Italy
Azienda Ospedaliero Universitaria Consorziale Policlinico /ID# 107820
Bari, Italy, 70124
Azienda Ospedaliera Papa Giovanni XXIII /ID# 107976
Bergamo, Italy, 24127
Ospedale San Giacomo Apostolo - Azienda ULSS 2 - Asolo /ID# 145552
Castelfranco Veneto, Italy, 31033
Azienda Socio-Sanitaria Territoriale- Ospedale di Cremona /ID# 104076
Cremona, Italy, 26100
Azienda Ospedaliera Universitaria San Martino /ID# 101155
Genova, Italy, 16132
Azienda Socio-Sanitaria Terriroriale di Lecco /ID# 103965
Lecco, Italy, 23900
Ospedale Versilia /ID# 142882
Lido di Camaiore (LU), Italy, 55041
Azienda Ospedaliera Universitaria G. Martino /ID# 147181
Messina, Italy, 98125
Azienda Socio-Sanitaria Territoriale (ASST)Santi Pal.e Carlo /ID# 107949
Milan, Italy, 20142
ASST Grande Ospedale Metropolitano Niguarda /ID# 104258
Milan, Italy, 20162
Ospedale S. Maria della Pieta di Naples /ID# 117036
Naples, Italy, 80035
Policlinico Universitario degli Federic /ID# 121357
Naples, Italy, 80131
Universita della Campania Luigi Vanvitelli /ID# 111615
Naples, Italy, 80138
Ospedale S. Maria del Popolo degli Incurabili /ID# 110335
Napoli, Italy, 80137
Fondazione IRCCS Policlinico S. Matteo Universita di Pavia /ID# 110995
Pavia, Italy, 27100
IRCCS Fondazione Salvatore Maugeri /ID# 103716
Pavia, Italy, 27100
ASL Cagliari /ID# 108615
Quartu Sant' Elena, Italy, 09045
Azienda Ospedaliera Bianchi Melacrino Morelli /ID# 131348
Reggio Calabria, Italy, 89124
Policlinico Univ Tor Vergata /ID# 121356
Rome, Italy, 00133
Azienda Ospedaliera Sant' Andrea /ID# 111017
Rome, Italy, 00189
IRCCS Casa Sollievo della Sofferenza /ID# 111018
San Giovanni Rotondo, Italy, 71013
Azienda Socio Sanitaria Territoriale dei Sette Laghi /ID# 111016
Varese, Italy, 21100
Japan
Nakadori General Hospital /ID# 118159
Akita-shi, Japan
National Hospital Organization Asahikawa Medical Center /ID# 106355
Asahikawa-shi, Japan
Shimizu Internal Medicine Clinic /ID# 109476
Asahikawa-shi, Japan
National Hospital Organization Chiba-East-Hospital /ID# 107575
Chiba-shi, Japan
Fukuoka University Chikushi Hospital /ID# 119496
Chikushino-shi, Japan
Japanese Red Cross Fukuoka Hospital /ID# 110775
Fukuoka-shi, Japan
Kyushu Central Hospital of Mutual Aid Association /ID# 108775
Fukuoka-shi, Japan
Funabashi Municipal Medical Center /ID# 110795
Funabashi-shi, Japan
Harada Clinic /ID# 109481
Hakodate-shi, Japan
Takahashi Hospital, Social Medical Corporation /ID# 109495
Hakodate-shi, Japan
Anzai Clinic /ID# 109480
Hakodate, Japan
Hamamatsu Medical Center /ID# 108177
Hamamatsu-shi, Japan
Higashihiroshima Medical Center /ID# 105207
Higashihiroshima-shi, Japan
Iwata City Hospital /ID# 108176
Iwata-shi, Japan
Rinku General Medical Center /ID# 107056
Izumisano-shi, Japan
Shimane University Hospital /ID# 111056
Izumo, Japan
Tempozan Clinic of Internal Medicine /ID# 117619
Kagoshima, Japan
St. Marianna University School of Medicine Hospital /ID# 110756
Kanagawa, Japan
Kasugai Municipal Hospital /ID# 130651
Kasugai-shi, Japan
Kawanishi City Hospital /ID# 119140
Kawanishi-shi, Japan
Kokura Memorial Hospital /ID# 109499
Kitakyushu-shi, Japan
Kobe City Medical Center West Hospital /ID# 110755
Kobe-shi, Japan
Showa General Hospital /ID# 108175
Kodaira-shi, Japan
Itabashi Clinic /ID# 118515
Koga-shi, Japan
Dokkyo Medical University Koshigaya Hospital /ID# 118516
Koshigaya-shi, Japan
Koshigaya Municipal Hospital /ID# 106335
Koshigaya-shi, Japan
Kumamoto Medical Center /ID# 105206
Kumamoto-shi, Japan
Kawasaki Medical School Hospital /ID# 102635
Kurashiki-shi, Japan
St. Mary's Hospital /ID# 108696
Kurume-shi, Japan
Kyoto City Hospital /ID# 109477
Kyoto-shi, Japan
Rakuwakai Otowa Hosptial /ID# 107055
Kyoto-shi, Japan
Takeda General Hospital /ID# 109501
Kyoto-shi, Japan
Matsue Red Cross Hospital /ID# 108204
Matsue-shi, Japan
General Foundation Eiraikai Matsuyama Shimin Hospital /ID# 119638
Matsuyama-shi, Japan
Saiseikai Matsuyama Hospital /ID# 105218
Matsuyama, Japan
Chita Kosei Hospital /ID# 109497
Mihama-cho, Japan
Miyazaki Prefectural Miyazaki Hospital /ID# 119136
Miyazaki-shi, Japan
Ato Internal Medicine Clinic /ID# 118157
Muroran-shi, Japan
Chubu Rosai Hospital /ID# 107035
Nagoya-shi, Japan
Meitetsu Hospital /ID# 107557
Nagoya-shi, Japan
NHO Nagoya Medical Center /ID# 108195
Nagoya-shi, Japan
Nakakinen Clinic /ID# 107037
Naka-shi, Japan
Saiseikai Niigata Daini Hospital /ID# 107558
Niigata-shi, Japan
Kobari General Clinic /ID# 119141
Noda-shi, Japan
Jiyugaoka Yamada Clinic /ID# 109479
Obihiro-shi, Japan
Obihiro Dai-ichi Hospital /ID# 125535
Obihiro-shi, Japan
Takagi Hospital /ID# 109500
Okawa-shi, Japan
Osaka General Medical Center /ID# 119636
Osaka-shi, Japan
Osaka Gyoumeikan Hospital /ID# 117755
Osaka-shi, Japan
Otsu City Hospital /ID# 107560
Otsu-shi, Japan
Ibaraki Seinan Medical Center Hospital /ID# 108178
Sakai-machi, Japan
Asama General Hospital /ID# 109478
Saku-shi, Japan
Sanuki Municipal Hospital /ID# 108735
Sanuki-shi, Japan
Manda Memorial Hospital /ID# 129396
Sapporo-shi, Japan
Sapporo Medical Center NTT EC /ID# 107615
Sapporo-shi, Japan
Suruga Clinic /ID# 106357
Shizuoka-shi, Japan
Shunan City Shinnanyo Hospital /ID# 117756
Shunan-shi, Japan
Takamatsu Red Cross Hospital /ID# 107559
Takamatsu-shi, Japan
Takatsuki Red Cross Hospital /ID# 107038
Takatsuki-shi, Japan
Tamana Central Hospital /ID# 108676
Tamana-shi, Japan
Tokushima University Hospital /ID# 105217
Tokushima-shi, Japan
MAKITA General Hospital /ID# 121200
Tokyo, Japan
National Center for Global Health and Medicine Hospital /ID# 117757
Tokyo, Japan
Sato Medical Clinic /ID# 148308
Tokyo, Japan
The Institute for Adult Diseases /ID# 128316
Tokyo, Japan
Tokyo Kamata Medical Center /ID# 108675
Tokyo, Japan
Tokyo-Eki Center-Building Clinic /ID# 129395
Tokyo, Japan
JA Toride Medical Center /ID# 107057
Toride-shi, Japan
Toyota Memorial Hospital /ID# 109502
Toyota-shi, Japan
Mie Central Medical Center /ID# 107036
Tsu-shi, Japan
Fujii Clinic /ID# 122397
Ube, Japan
National Hospital Organization Shinshu Ueda Medical Center /ID# 106356
Ueda-shi, Japan
Urasoe Sogo Hospital /ID# 107616
Urasoe-shi, Japan
Okamoto Internal Medicine Office /ID# 109475
Yaizu-shi, Japan
HEC Science Clinic /ID# 132529
Yokohama-shi, Japan
National Hospital Organization Yokohama Medical Center /ID# 108196
Yokohama-shi, Japan
Tokui Internal Medicine Clinic /ID# 119578
Yokohama-shi, Japan
Nakajima Naika Clinic /ID# 129276
Yokosuka-shi, Japan
Korea, Republic of
Korea University Ansan Hospital /ID# 113417
Ansan-si, Korea, Republic of, 15355
Korea University Ansan Hospital /ID# 117616
Ansan-si, Korea, Republic of, 15355
Soonchunhayng University Bucheon Hospital /ID# 109235
Bucheon-si, Korea, Republic of, 14584
The Catholic University of Korea Bucheon St. Mary's hospital /ID# 102259
Bucheon-si, Korea, Republic of, 14647
Dong-A University Hospital /ID# 113797
Busan, Korea, Republic of, 49201
Inje University Busan Paik Hospital /ID# 113815
Busan, Korea, Republic of, 614-735
Chuncheon Sacred Heart Hospital /ID# 116376
Chuncheon, Korea, Republic of, 24253
Chungbuk National University Hospital /ID# 107942
Chungcheongbuk-do, Korea, Republic of, 28644
Keimyung University Dongsan Medical Center /ID# 112119
Daegu, Korea, Republic of, 41931
Yeungnam University Medical Center /ID# 113936
Daegu, Korea, Republic of, 42415
Daegu Catholic University Medical Center /ID# 109236
Daegu, Korea, Republic of, 42472
Kyungpook National University Hospital /ID# 102615
Daegu, Korea, Republic of, 700-721
Chungnam National University Hospital /ID# 112120
Daejeon, Korea, Republic of, 35015
Wonju Severance Christian Hospital /ID# 107943
Gangwon-do, Korea, Republic of, 26426
Myongji Hospital /ID# 117016
Goyang-si, Korea, Republic of, 10475
Chosun University Hospital /ID# 117015
Gwangju, Korea, Republic of, 61453
Hanyang University Guri Hospital /ID# 113798
Gyeonggi-do, Korea, Republic of, 11923
Bundang Cha Hospital /ID# 110557
Gyeonggi-do, Korea, Republic of, 13496
Wonkwang University School Of Medicine & Hospital /ID# 116378
Iksan, Korea, Republic of, 54538
Gachon University Gill Hospital /ID# 116379
Incheon, Korea, Republic of, 21565
Jeju National University Hospital /ID# 117615
Jeju-do, Korea, Republic of, 63241
Chonbuk National University Hospital /ID# 110655
Jeonju-si, Korea, Republic of, 54907
Pusan National University Hospital /ID# 102258
Pusan, Korea, Republic of, 49241
Seoul National University Bundang Hospital /ID# 102256
Seongnam-si, Korea, Republic of, 13620
Kyung Hee University Medical Center /ID# 104757
Seoul, Korea, Republic of, 02447
Korea University Anam Hospital /ID# 112117
Seoul, Korea, Republic of, 02841
Seoul National University Hospital /ID# 104755
Seoul, Korea, Republic of, 03080
Severance Hospital /ID# 117617
Seoul, Korea, Republic of, 03722
Gangdong Kyunghee University Hospital /ID# 104756
Seoul, Korea, Republic of, 05278
Hallym University Kangdong Sacred Heart Hospital /ID# 102257
Seoul, Korea, Republic of, 05355
Asan Medical Center /ID# 117017
Seoul, Korea, Republic of, 05505
Gangnam Severance Hospital /ID# 102255
Seoul, Korea, Republic of, 06273
Samsung Medical Center /ID# 102617
Seoul, Korea, Republic of, 06351
The Catholic Univ. of Korea, Seoul, St. Mary's Hospital /ID# 106657
Seoul, Korea, Republic of, 06591
Korea Universtiy Guro Hospital /ID# 109599
Seoul, Korea, Republic of, 08308
The Catholic University of Korea St. Paul's Hospital /ID# 116375
Seoul, Korea, Republic of, 130-709
Ajou University Hospital /ID# 102616
Suwon-si, Korea, Republic of, 16499
Uijeongbu St. Mary's Hospital /ID# 109217
Uijeongbu, Korea, Republic of, 11765
Ulsan University Hospital /ID# 107758
Ulsan, Korea, Republic of, 44033
Malaysia
Hospital Sultanah Bahiyah /ID# 135212
Alor Setar, Malaysia, 05460
Hospital Selayang /ID# 111875
Batu Caves, Malaysia, 68100
Klinik Kesihatan Greentown /ID# 135213
Ipoh, Malaysia
Hospital Sultanah Aminah /ID# 135210
Johor Bahru, Malaysia, 80100
Monash University Malaysia /ID# 141598
Johor, Malaysia, 80100
Hospital Serdang /ID# 113817
Kajang, Malaysia, 43000
Hospital Raja Perempuan Zainab II /ID# 109578
Kota Bharu, Malaysia, 15586
University Sains Malaysia /ID# 107937
Kota Bharu, Malaysia, 16150
Hospital Kuala Lumpur /ID# 113816
Kuala Lumpur, Malaysia, 50586
Hospital Universiti Kebangsaan Malaysia /ID# 113835
Kuala Lumpur, Malaysia, 56000
Hospital Tengku Ampuan Afzan /ID# 113855
Kuantan, Malaysia, 25000
Hospital Melaka /ID# 112121
Melaka, Malaysia, 75400
Monash University Malaysia /ID# 139217
Petaling Jaya, Malaysia, 461500
Hospital Pulua Pinang c/o Penang Medical College /ID# 109579
Pulau Pinang, Malaysia, 10450
Hospital Putrajaya /ID# 110558
Putrajaya, Malaysia, 62250
Hospital Queen Elizabeth II /ID# 150110
Sabah, Malaysia, 88300
Hospital Tuanku Ja afar /ID# 113819
Seremban, Malaysia, 70300
Hospital Taiping /ID# 109595
Taiping, Malaysia, 34000
Hospital Taiping /ID# 113818
Taiping, Malaysia, 34000
Mexico
Centro de Investigacion Clinica del Pacifico /ID# 101775
Acapulco, Mexico, C.P. 39670
Clinica San Cosme /ID# 104364
Aguascalientes, Mexico, 20219
Instituto de Diabetes Obesidad y Nutricion S.C. /ID# 101755
Cuernavaca, Morelos, Mexico, 62250
Investigacion Nefrologica S.C. /ID# 107940
Cuernavaca, Morelos, Mexico, C.P. 62448
Instituto Jalisciense de Investigacion en Diabetes Obesidad /ID# 100777
Guadalajara, Mexico, 44600
Area Medica SANEFRO /ID# 104695
Guadalajara, Mexico, CP 44190
Instituto Nacional de Cardiologia "Ignacio Chavez" /ID# 107481
Mexico DF, Mexico, CP 14080
Paracelsus, S.A. de C.V. /Id# 107480
Mexico, D.f., Mexico, 03800
Instituto Nacioanl de Ciencias Medicas Nutricion S. Zubiran /ID# 104366
Mexico, Mexico, 14080
Hospital Universitario Dr. Jose Eleuterio Gonzalez /ID# 100564
Monterrey, N.L., Mexico, C.P. 64460
Hospital y Clinica OCA /ID# 100778
Monterrey, Nuevo Leon, Mexico, C.P. 64000
Unidad de Prevencion y Atencion Cardiometabolica (UPAC) /ID# 101555
Morelia, Michoacan, Mexico, C.P. 58260
Hospital Central Dr. Ignacio Morones Prieto /ID# 102558
San Luis Potosi, Mexico, C.P. 78240
Netherlands
Ziekenhuis Groep Twente /ID# 100907
Almelo, Netherlands, 7609 PP
Meander Medisch Centrum /ID# 107836
Amersfoort, Netherlands, 3813 TZ
Academic Medical Center Amsterdam /ID# 132688
Amsterdam, Netherlands, 1105 AZ
Gelre Hospital Apeldoorn /ID# 101235
Apeldoorn, Netherlands, 7334 DZ
Albert Schweitzer Ziekenhuis /ID# 100332
Dordrecht, Netherlands, 3318 AT
University Medical Center Groningen /ID# 100331
Groningen, Netherlands, 9713 GZ
New Zealand
Auckland City Hospital /ID# 107945
Auckland, New Zealand, 1023
Middlemore Clinical Trials /ID# 132508
Auckland, New Zealand, 2025
Canterbury District Health Board /ID# 134228
Christchurch, New Zealand, 8011
Dunedin Hospital /ID# 102595
Dunedin, Otago, New Zealand, 9054
Waikato Hospital /ID# 110575
Hamilton, New Zealand, 3240
Taranaki Base Hospital /ID# 110576
New Plymouth, New Zealand, 4310
North Shore Hospital /ID# 120435
Takapuna, New Zealand, 0622
Peru
Exacta Lab SAC /ID# 104195
Arequipa, Peru
Instituto Delgado de Investigacion Medica /ID# 104368
Arequipa, Peru
Instituto Endocronolocigo Farfan E.I.R.L /ID# 99435
Arequipa, Peru
Hospital Nacional Alberto Sabogal Sologuren /ID# 104370
Callao 2, Peru
Hospital Nacional Adolfo Guevara Velasco Essalud /ID# 102176
Cusco, Peru
Hospital Nacional Arzobispo Loayza /ID# 104837
Lima, Peru, LIMA 01
Clinica de Diabetes S.A.C. /ID# 100567
Lima, Peru, LIMA 17
Centro de Investigacion y Atencion Cardiovascular SAC. /ID# 100566
Lima, Peru, LIMA 27
Centro Medico Clinica San Judas Tadeo /ID# 102877
Lima, Peru, LIMA 32
Clinica Virgen Maria Auxiliadora /ID# 104371
Piura, Peru
Poland
NZOZ Specjalistyczny Osrodek /ID# 104231
Bialystok, Poland, 15-435
NZOZ Diab Serwis S.C. /ID# 110596
Chorzow, Poland, 41-500
Samodzielny Publiczny Szpital Kliniczny /ID# 118179
Katowice, Poland, 40-027
Nzoz Salvia /Id# 100570
Katowice, Poland, 40-772
Krakowskie Centrum Medyczne Sp. z o.o. /ID# 100569
Krakow, Poland, 31-501
Centrum Medyczne ProMiMed Sp z.o.o. Sp. k. /ID# 108559
Krakow, Poland, 31-637
SPZOZ Uniwersytecki Szpital Kliniczny im. WAM /ID# 109996
Lodz, Poland, 92-213
NZOZ Przychodnia Specjalistyczna MEDICA /ID# 100571
Lublin, Poland, 20-538
Centrum Medyczne Medyk /ID# 108561
Rzeszow, Poland, 35-055
Centrum Uslug Medycznych Dializa /ID# 108560
Szczecinek, Poland, 78-400
Samodzielny Publiczny Szpital Kliniczny Nr 2 PUM w Szczecini /ID# 116995
Szczecin, Poland, 70-111
Medica pro Familia SA /ID# 100568
Warsaw, Poland, 01-868
Portugal
Hospital Garcia de Orta, E.P.E /ID# 141333
Almada, Portugal, 2805-267
Hospital de Faro, EPE /ID# 108438
Faro, Portugal, 8000-386
Hospital Curry Cabral /ID# 100897
Lisbon, Portugal, 1069-166
Associacao Protectora dos Diabeticos de Portugal /ID# 104316
Lisbon, Portugal, 1250-203
Hospital de Santa Maria /ID# 150676
Lisbon, Portugal, 1649-035
Centro Hospitalar do Porto,EPE /ID# 104315
Porto, Portugal, 4099-100
Puerto Rico
Centro de Endocrinologia Alcantara-Gonzalez /ID# 136011
Bayamon, Puerto Rico, 00956
Health Preventive Services /ID# 110477
Bayamon, Puerto Rico, 00961
Instituto Renal del Este /ID# 104855
Caguas, Puerto Rico, 00725
Advanced Medical Concepts. PSC /ID# 135170
Cidra, Puerto Rico, 00739
Endocrine Lipid Diabetes Research Institute of Puerto Rico /ID# 136012
Ponce, Puerto Rico, 00717-2075
Research and Cardiovascular Corporation /ID# 104838
Ponce, Puerto Rico, 00717
Caparra Internal Medicine /ID# 106295
Rio Grande, Puerto Rico, 00745
University of Puerto Rico, Medical Sciences Campus /ID# 104857
Rio Piedras, Puerto Rico, 00935
Nephrology Private Practice /ID# 103455
San Juan, Puerto Rico, 00918
VA Caribbean Healthcare System (VACHS) /ID# 122115
San Juan, Puerto Rico, 00921-3201
Dr. Luis J. Quesada Office /ID# 105675
Santurce, Puerto Rico, 00909-2244
PR Renal Health and Research INC. /ID# 123635
Toa Baja, Puerto Rico, 00949
Romania
O.D. Medica SRL /ID# 100324
Bucharest, Romania, 020725
Spitalul Clinic Judetean de Urgenta Cluj-Napoca /ID# 108056
Cluj-Napoca, Romania, 400006
Centrul Medical Unirea SRL /ID# 100322
Cluj-Napoca, Romania, 400349
Spitalul Clinic Judetean de Urgenta Constanta /ID# 111175
Constanta, Romania, 900591
Milena Sante SRL /ID# 107577
Galati, Romania, 800001
Consultmed SRL /ID# 108057
Iasi, Romania, 700547
Municipal Clinical Hospital "Dr. Gavrill Curteanu" Oradea /ID# 101156
Oradea, Romania, 410469
Spitalul Judetean de Urgenta Pitesti /ID# 100325
Pitesti, Romania, 110084
SC Centrul Medical "Sfantul Stefan" SRL /ID# 100323
Timisoara, Romania, 300125
Sptalul Clinic Judetean de Urgenta Timisoara /ID# 104230
Timisoara, Romania, 300736
Sptalul Clinic Judetean de Urgenta Timisoara /ID# 108058
Timisoara, Romania, 300736
Russian Federation
archangel Clinical Oncology Dispensary /ID# 103237
Arkhangelsk, Russian Federation, 163045
Regional Clinical Hospital /ID# 103251
Barnaul, Russian Federation, 656024
City Hospital No 6 /ID# 104223
Chelyabinsk, Russian Federation, 454047
LLC "Clinic of New Technologies of Medicine" /ID# 104356
Dzerzhinskiy, Russian Federation, 140091
Gatchina Central District Clinical Hospital /ID# 104653
Gatchina, Russian Federation, 188300
Irkutsk State Medical Academy of Postgraduate Education /ID# 100901
Irkutsk, Russian Federation, 664079
Kazan State University /ID# 100362
Kazan, Russian Federation, 420064
Kazan State University /ID# 104436
Kazan, Russian Federation, 420064
Kemerovo Regional Clinical Hospital /ID# 103244
Kemerovo, Russian Federation, 650066
Kirov City Clinical Hospital 1 /ID# 104079
Kirov, Russian Federation, 610014
Krasnoyarsk Interdistrict Clinical Emergency Care Hospital /ID# 100358
Krasnoyarsk, Russian Federation, 660062
City Clinical Hospital #23 named after Medsantrud /ID# 103242
Moscow, Russian Federation, 109240
Endocrinology Research Center /ID# 104657
Moscow, Russian Federation, 117036
People's Friendship University of Russia /ID# 149241
Moscow, Russian Federation, 117292
Moscow State Medical University n.a. I.M. Sechenov /ID# 103240
Moscow, Russian Federation, 119881
Moscow State HC Institution City Clinical Hosp No. 52 /ID# 108563
Moscow, Russian Federation, 123182
Moscow - Out-patient Clinic #3 /ID# 107735
Moscow, Russian Federation, 129090
City Hosp 33 of Leninskiy District of City Nizhniy Novgorod /ID# 104667
Nizhniy Novgorod, Russian Federation, 603076
Scientific Instituti of Clinical and Experimental Lymphology /ID# 100356
Novosibirsk, Russian Federation, 630117
Orenburg State Medical Academy /ID# 108562
Orenburg, Russian Federation, 460018
Perm Regional Hospital for War Veterans /ID# 103239
Perm, Russian Federation, 614097
Republican Clinical Hospital n.a. Baranov /ID# 104400
Petrozavodsk, Russian Federation, 185019
City Consultative diagnostic center №1 /ID# 104435
Saint-Petersburg, Russian Federation, 194354
City Out-patient Clinic #17 /ID# 99437
Saint-Petersburg, Russian Federation, 195213
City Clinical Hospital # 38 named after N.A. Semashko /ID# 103252
Saint-Petersburg, Russian Federation, 196601
St. Petersburg Medical Univ na I.P. Pavlov /ID# 104227
Saint-Petersburg, Russian Federation, 197022
City Clinical Hospital # 31 /ID# 104417
Saint-Petersburg, Russian Federation, 197110
GBOU VPO Saratov State Medical University /ID# 104937
Saratov, Russian Federation, 410054
Smolensk State Medical Academy /ID# 104475
Smolensk, Russian Federation, 214019
Northwest State Medical University NA Mechnikov /ID# 103238
St. Petersburg, Russian Federation, 191015
Federal State Institution /ID# 100361
St. Petersburg, Russian Federation, 199034
Research Institute for Cardiology /ID# 100879
Tomsk, Russian Federation, 634012
Siberian State Medical University /ID# 100360
Tomsk, Russian Federation, 643050
Regional Clinical Hospital of Yaroslavl Region /ID# 104078
Yaroslavl, Russian Federation, 150062
Singapore
National University Hospital /ID# 110578
Singapore, Singapore, 119228
Singapore General Hospital Pte Ltd /ID# 135214
Singapore, Singapore, 169608
Tan Tock Seng Hospital /ID# 107938
Singapore, Singapore, 308433
Khoo Teck Puat Hospital /ID# 110577
Singapore, Singapore, 768828
Slovakia
ProVitae-Medical Centre /ID# 113616
Bratislava, Slovakia, 81103
FMC Dialysis Services /ID# 103964
Bratislava, Slovakia, 82606
Metabolic Center of Dr K.Raslova, ltd /ID# 100326
Bratislava, Slovakia, 83301
Slovenska Zdravotnica Univerzita /ID# 108577
Bratislava, Slovakia, 83303
Medispektrum, sro /ID# 103957
Bratislava, Slovakia, 85101
FMC-dialyzacne sluzby, spol.s r.o /ID# 118758
Hlohovec, Slovakia, 92001
AGTO spol. s.r.o. /ID# 100903
Kosice, Slovakia, 040 01
Medikol s.r.o. /ID# 100902
Kosice, Slovakia, 040 01
FMC Dialyzacne sluzby s.r.o. /ID# 103959
Kosice, Slovakia, 04011
SMOLKO s.r.o. /ID# 118756
Kosice, Slovakia, 04011
B Braun Avitum s.r.o. /ID# 118739
Kralovsky Chlmec, Slovakia, 077 01
Interna SK s.r.o. /ID# 118757
Svidnik, Slovakia, 08901
South Africa
Langeberg Clinical Trials /ID# 107979
Cape Town, South Africa, 7570
Groote Schuur Hospital /ID# 103966
Cape Town, South Africa, 7925
Unitas Hospital /ID# 148309
Centurion Lyttelton, South Africa, 0157
St. Augustine's Hospital /ID# 107995
Durban, South Africa, 4001
Newkwa Medical Centre /ID# 107982
Durban, South Africa, 4037
Dot Shuttleworth Centre for Diabetes /ID# 100327
Durban, South Africa, 4091
Dr P J Sebastian /ID# 107980
Durban, South Africa, 4092
Newtown Clinical Research Center /ID# 145712
Johannesburg, South Africa, 2113
LCS Clinical Research Unit /ID# 132509
Johannesburg, South Africa, 2188
Centre for Diabetes and Endocrinology /ID# 101158
Johannesburg, South Africa, 2198
Makan, Lenasia, SA /ID# 125616
Lenasia, South Africa, 1827
Paarl Research Centre /ID# 107981
Paarl, South Africa, 7646
Phoenix Pharma /ID# 132510
Port Elizabeth, South Africa, 6001
Synexus Helderberg Clinical Trials Centre /ID# 100329
Somerset West, South Africa, 7130
Soweto Clinical Trial Centre /ID# 125615
Soweto, South Africa, 1818
Clinical Projects Research /ID# 100328
Worcester, South Africa, 6850
Spain
Complejo Hospitalario Universitario de A Coruna /ID# 104095
A Coruna, Spain, 15006
Hospital Parc de Salut del Mar /ID# 100330
Barcelona, Spain, 08003
Fundacion Puigvert /ID# 107458
Barcelona, Spain, 08025
Hospital Universitario Bellvitge /ID# 103136
Barcelona, Spain, 08907
Hospital Universitari Germans Trias I Pujol /ID# 103717
Barcelona, Spain, 08916
Hospital Vall d'Hebron /ID# 104660
Barcelona, Spain, 8035
Hospital Universitario de Basurto /ID# 100904
Bilbao, Spain, 48013
Hospital da Costa /ID# 100572
Burela, Spain, 27880
Hospital Universitario Reina Sofia /ID# 107816
Cordoba, Spain, 14004
Hospital Universitari de Girona Dr. Josep Trueta /ID# 100574
Gerona, Spain, 17007
Hospital Universitario de Gran Canarias Dr. Negrin /ID# 106775
Las Palmas, Spain, 35010
Complejo Asistencial Universitario de Leon /ID# 140358
Leon, Spain, 24071
Hospital Universitario Arnau de Vilanova /ID# 109456
Lleida, Spain, 25198
Fundacion Jimenez Diaz /ID# 104222
Madrid, Spain, 28040
Hospital Universitario Clinico San Carlos /ID# 106216
Madrid, Spain, 28040
Hospital Universitario 12 de Octubre /ID# 106218
Madrid, Spain, 28041
Hospital Universitarrio Puerta de Hierro Majadahonda /ID# 124276
Madrid, Spain, 28222
Hospital Universitario de Getafe /ID# 138097
Madrid, Spain, 28905
Hospital Universitario Virgen de la Victoria /ID# 104661
Malaga, Spain, 29010
Hospital Parc Tauli /ID# 144261
Sabadell (Barcelona), Spain, 08208
Hospital Universitario Marques de Valdecilla /ID# 103135
Santander (Cantabria), Spain, 39008
Hospital Universitario Virgen Macarena /ID# 106217
Seville, Spain, 41071
Hospital Universitario Nuestra Senora de Candelaria /ID# 107997
Tenerife, Spain, 38010
Hospital de Terrassa Consorci Sanitari de Terrassa /ID# 147093
Terrasa, Barcelona, Spain, 08227
Hospital General Universitario de Valencia /ID# 104224
Valencia, Spain, 46014
Hospital Universitario Dr. Peset /ID# 105517
Valencia, Spain, 46017
Hospital Universitario y Politecnico La Fe /ID# 107815
Valencia, Spain, 46026
Hospital de Txagorritxu /ID# 106219
Vitoria, Spain, 01009
Sweden
Sahlgrenska University Hospital /ID# 104663
Gothenburg, Sweden, 413 45
Orebro Universitetssjukhuset /ID# 100905
Orebro, Sweden, 70185
Uppsala University Hospital /ID# 104662
Uppsala, Sweden, SE-751 85
Switzerland
Kantonsspital Aarau /ID# 106197
Aarau, Switzerland, CH-5001
Taiwan
Hualien Tzu Chi Hospital /ID# 109596
Hualien, Taiwan
Kaohsiung Chang Gung Memorial Hospital /ID# 109216
Kaohsiung City, Taiwan, 833
Kaohsiung Veterans General Hospital /ID# 141597
Kaohsiung, Taiwan, 813
Cardinal Tien Hospital /ID# 106658
New Taipei City, Taiwan
Far Eastern Memorial Hospital /ID# 107936
New Taipei, Taiwan, 220
Chung Shan Medical University /ID# 108755
Taichung City, Taiwan, 40242
China Medical University Hospital /ID# 103075
Taichung City, Taiwan, 40447
Taichung Veterans General Hospital /ID# 103076
Taichung, Taiwan, 40705
Kuang Tien General Hospital /ID# 111856
Taichung, Taiwan, 433
Taichung Hospital /ID# 113937
Taichung, Taiwan
Chi-Mei Medical Center - Yong Kang /ID# 111855
Tainan, Taiwan, 710
Taipei Medical University Hospital /ID# 111035
Taipei City, Taiwan, 110
Cathay General Hospital /ID# 109598
Taipei, Taiwan, 106
Turkey
Baskent University School of Medicine /ID# 108579
Ankara, Turkey, 06490
Akdeniz University Medical Faculty /ID# 100335
Antalya, Turkey, 07058
Adnan Menderes University /ID# 114415
Aydin, Turkey, 09100
Ondokuz mayis University Faculty of Medicine Discipline of R /ID# 108580
Edirne, Turkey, 22030
Istanbul University Medical Faculty /ID# 108315
Istanbul, Turkey, 34093
Istanbul University Medical Faculty /ID# 111177
Istanbul, Turkey, 34093
Sifa University Medical Faculty Health Research Hospital /ID# 111178
Izmir, Turkey, 35100
Kocaeli University Medical Faculty /ID# 108578
Kocaeli, Turkey, 41380
Ukraine
Chernivtsi Regional Clinical Hospital /ID# 104495
Chernivtsi, Ukraine, 58001
Dnipropetrovsk Regional Clinical Hospital na Mechnykov /ID# 104127
Dnipropetrovsk, Ukraine, 49005
Ukrainian State Institution of Medical and Social Problems /ID# 104126
Dnipropetrovsk, Ukraine, 49027
Ivano-Frankivsk Regional Clinical Hospital /ID# 104558
Ivano-Frankivsk, Ukraine, 76008
Municipal Health Care Institution Kharkov City Clinical /ID# 104517
Kharkiv, Ukraine, 61002
State Institute L.T. Mala Therapy Nat Inst. of NAMS of UA /ID# 113995
Kharkiv, Ukraine, 61039
Kharkiv City Clinical Emergency Hospital /ID# 103936
Kharkiv, Ukraine, 61103
Institute of Nephrology NAMS of Ukraine /ID# 104117
Kiev, Ukraine, 04050
Institute of Nephrology NAMS of Ukraine /ID# 104673
Kiev, Ukraine, 04050
Polyclinic of Administration of Medical Services /ID# 107477
Kiev, Ukraine, 04050
VP Komissarenko National Academy of Medical Sciences /ID# 107475
Kiev, Ukraine, 04114
Kiev Regional Clinical Hospital /ID# 104122
Kyiv, Ukraine, 04107
VP Komissarenko National Academy of Medical Sciences /ID# 104118
Kyiv, Ukraine, 04114
Lviv Regional Clinical Hospital,Lviv National /ID# 104116
Lviv, Ukraine, 79010
Mykolayiv Regional Hospital /ID# 104997
Mykolayiv, Ukraine, 54058
Communal Institution Odesa Regional Clinical Hospital /ID# 107461
Odesa, Ukraine, 65025
Ternopil University Hospital, Communal Institution /ID# 104121
Ternopil, Ukraine, 46002
Transcarpathian Regional Clin. Hos. Named after Andriy Novak /ID# 104216
Uzhgorod, Ukraine, 88018
Vinnytsia National Medical University n.a. M.I. Pyrogov /ID# 105275
Vinnytsia, Ukraine, 21018
Clinic of Scientific Research Institute for Hadicapped /ID# 104672
Vinnytsya, Ukraine, 21030
Central Hospital of Ordjonikidze District /ID# 104125
Zaporizhzhya, Ukraine, 69001
Regional Clinical Hospital of Zhytomyr /ID# 100909
Zhytomyr, Ukraine, 10002
United Kingdom
Belfast City Hospital /ID# 109976
Belfast, Nothern Ireland, United Kingdom, BT9 7AB
Ninewells Hospital /ID# 104665
Dundee, United Kingdom, DD1 9SY
South Glasgow Universita Hospital /ID# 104666
Glasgow, United Kingdom, G51 4TF
North Middlesex Hospital NHS Trust /ID# 113595
London, United Kingdom, N18 1QX
The Royal Free Hospital /ID# 113382
London, United Kingdom, NW3 2QG
Guy's Hospital /ID# 106235
London, United Kingdom, SE1 9RT
King College Hospital, King's College Hospital NHS Foundatio /ID# 104664
London, United Kingdom, SE5 9RS
Salford Royal NHS Foundation Trust /ID# 113916
Salford, United Kingdom, M6 8HD
Sponsors and Collaborators
AbbVie
Investigators
Study Director: Melissa Wigderson, MD AbbVie
  More Information

Responsible Party: AbbVie
ClinicalTrials.gov Identifier: NCT01858532     History of Changes
Other Study ID Numbers: M11-352
2012-005848-21 ( EudraCT Number )
First Submitted: May 17, 2013
First Posted: May 21, 2013
Last Update Posted: October 24, 2017
Last Verified: October 2017

Keywords provided by AbbVie:
Diabetes
Nephropathy

Additional relevant MeSH terms:
Kidney Diseases
Diabetic Nephropathies
Urologic Diseases
Diabetes Complications
Diabetes Mellitus
Endocrine System Diseases
Atrasentan
Endothelin Receptor Antagonists
Molecular Mechanisms of Pharmacological Action