S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer (S1216)
|
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
| ClinicalTrials.gov Identifier: NCT01809691 |
|
Recruitment Status
:
Active, not recruiting
First Posted
: March 13, 2013
Last Update Posted
: August 17, 2017
|
Sponsor:
Southwest Oncology Group
Collaborators:
Millennium Pharmaceuticals, Inc.
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Southwest Oncology Group
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Brief Summary:
The purpose of this study is to compare overall survival in newly diagnosed metastatic prostate cancer patients randomly assigned to androgen deprivation therapy (ADT) + TAK-700 versus ADT + bicalutamide.
| Condition or disease | Intervention/treatment | Phase |
|---|---|---|
| Prostate Cancer | Drug: TAK-700 Drug: Bicalutamide | Phase 3 |
| Study Type : | Interventional (Clinical Trial) |
| Actual Enrollment : | 1313 participants |
| Allocation: | Randomized |
| Intervention Model: | Parallel Assignment |
| Masking: | None (Open Label) |
| Primary Purpose: | Treatment |
| Official Title: | A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 With Androgen Deprivation Therapy + Bicalutamide in Patients With Newly Diagnosed Metastatic Sensitive Prostate Cancer |
| Study Start Date : | March 2013 |
| Estimated Primary Completion Date : | March 2022 |
| Estimated Study Completion Date : | October 2027 |
Resource links provided by the National Library of Medicine
Genetics Home Reference related topics:
Prostate cancer
MedlinePlus related topics:
Prostate Cancer
Drug Information available for:
Bicalutamide
U.S. FDA Resources
| Arm | Intervention/treatment |
|---|---|
|
Experimental: ADT + TAK-700
LHRH agonist - given as approved for androgen deprivation at a dose necessary to maintain castrate levels and equivalent to 22.5 mg of Leuprolide IM every 3 months. TAK-700, 300 mg, PO, twice daily |
Drug: TAK-700
300 mg, PO, twice daily
Other Name: Orteronel
|
|
Active Comparator: ADT + Bicalutamide
LHRH agonist - given as approved for androgen deprivation at a dose necessary to maintain castrate levels and equivalent to 22.5 mg of Leuprolide IM every 3 months. Bicalutamide, 50 mg, PO, q daily |
Drug: Bicalutamide
50 mg, PO, q daily
Other Name: Casodex
|
Primary Outcome Measures
:
- Overall survival [ Time Frame: 3.2 years ]
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- Clinical diagnosis of metastatic prostate cancer.
- Serum testosterone within institutional limits of normal.
- PSA ≥ 2 ng/mL within 90 days prior to initiation of androgen deprivation. therapy (for early induction) or prior to registration (for late induction).
- DEXA scan within 2 years prior to registration.
- ECG within 42 days prior to registration and QTc interval ≤ 460 msec.
- LVEF within 42 days prior to registration and within institutional limits of normal.
- Adequate hepatic function as evidenced by bilirubin ≤ 2 x institutional upper limit of normal (ULN), SGOT (AST) and SGPT (ALT) ≤ 3 x institutional ULN, or ≤ 5 x institutional ULN if liver metastases are present.
- Adequate renal function as evidenced by calculated creatinine clearance ≥ 40 mL/min.
- Adequate hematologic function as evidenced by leukocytes ≥ 3,000/mcL, absolute neutrophil count (ANC) ≥ 1,500/mcL, hemoglobin ≥ 9 g/dL, and platelets ≥ 100,000/mcL.
- Zubrod performance status of 0 - 2. Zubrod performance status 3 will be allowed if from bone pain only.
- ≥ 18 years of age.
- Men of reproduction potential and those who are surgically sterilized (i.e., postvasectomy) must agree to practice effective barrier contraception or agree to abstain from intercourse while receiving treatment on this study and for at least 4 months after protocol treatment ends.
Exclusion Criteria:
- Known brain metastases.
- No more than 36 months of prior neoadjuvant and/or adjuvant hormonal therapy.
- ≥ 6 months since completion of androgen deprivation therapy.
- Prior or concurrent therapy with ketoconazole, aminoglutethimide or abiraterone acetate, or enzalutamide (MDV3100). Concurrent megestrol for hot flashes is allowed.
- Prior chemotherapy for treatment of metastatic prostate cancer. Prior chemotherapy in the neoadjuvant or adjuvant setting is allowed.
- ≥ 2 years since completion of chemotherapy in the neoadjuvant or adjuvant setting.
- Concurrent use of experimental therapy is not allowed.
- ≥ 30 days since prior medical castration for metastatic prostate cancer.
- If method of castration is a LHRH agonist, the patient must be willing to continue the use of LHRH and add bicalutamide or TAK-700 during protocol treatment.
- If the patient was on an antiandrogen (e.g. bicalutamide, flutamide), the patient must be willing to switch over to bicalutamide or TAK-700 (according to randomization).
- Prior bilateral orchiectomy.
- Concurrent use of LHRH antagonists (e.g. Degarelix)
- Grade III/IV cardiac disease (as defined by the NYHA Criteria), thromboembolic event, unstable angina pectoris, myocardial infarction within 6 months, or serious uncontrolled cardiac arrhythmia.
- Uncontrolled hypertension (defined as blood pressure > 160 mmHg systolic and > 90 mmHg diastolic at 2 separate measurements no more than 60 minutes apart during the Screening visit) despite appropriate medical therapy.
- Known human immunodeficiency virus (HIV)infection, active chronic hepatitis B or C, life-threatening illness unrelated to cancer, or any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with participation in this study.
- History of primary and secondary adrenal insufficiency.
- Hypersensitivity to TAK-700, to TAK-700 metabolites, to bicalutamide, or to LHRH agonists.
- Gastrointestinal (GI) disease or GI procedure that could interfere with the GI absorption or tolerance of TAK-700, including difficulty swallowing oral medications.
- No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, adequately treated Stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for 5 years.
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01809691
Hide Study Locations
Locations
| United States, Alabama | |
| Veterans Administration Medical Center - Birmingham | |
| Birmingham, Alabama, United States, 35233 | |
| United States, Arizona | |
| University of Arizona Cancer Center at Saint Joseph's | |
| Phoenix, Arizona, United States, 85004 | |
| University of Arizona Cancer Center-Orange Grove Campus | |
| Tucson, Arizona, United States, 85704 | |
| University of Arizona Cancer Center-North Campus | |
| Tucson, Arizona, United States, 85719 | |
| Southern Arizona Veterans Affairs Health Center | |
| Tucson, Arizona, United States, 85723 | |
| The University of Arizona Medical Center-University Campus | |
| Tucson, Arizona, United States, 85724 | |
| United States, Arkansas | |
| Fowler Family Center for Cancer Care | |
| Jonesboro, Arkansas, United States, 72401 | |
| Veteran's Administration Medical Center | |
| Little Rock, Arkansas, United States, 72205 | |
| United States, California | |
| Kaiser Permanente-Deer Valley Medical Center | |
| Antioch, California, United States, 94531 | |
| Sutter Auburn Faith Hospital | |
| Auburn, California, United States, 95602 | |
| AIS Cancer Center at San Joaquin Community Hospital | |
| Bakersfield, California, United States, 93301 | |
| Alta Bates Summit Medical Center-Herrick Campus | |
| Berkeley, California, United States, 94704 | |
| Mills - Peninsula Hospitals | |
| Burlingame, California, United States, 94010 | |
| City of Hope Corona | |
| Corona, California, United States, 92879 | |
| Sutter Davis Hospital | |
| Davis, California, United States, 95616 | |
| City of Hope Comprehensive Cancer Center | |
| Duarte, California, United States, 91010 | |
| Kaiser Permanente-Fremont | |
| Fremont, California, United States, 94538 | |
| University Oncology Associates | |
| Fresno, California, United States, 93701 | |
| Kaiser Permanente | |
| Fresno, California, United States, 93720 | |
| UC San Diego Moores Cancer Center | |
| La Jolla, California, United States, 92093 | |
| Loma Linda University Medical Center | |
| Loma Linda, California, United States, 92354 | |
| Veterans Affairs Loma Linda Healthcare System | |
| Loma Linda, California, United States, 92357 | |
| Los Angeles County-USC Medical Center | |
| Los Angeles, California, United States, 90033 | |
| USC / Norris Comprehensive Cancer Center | |
| Los Angeles, California, United States, 90033 | |
| Fremont - Rideout Cancer Center | |
| Marysville, California, United States, 95901 | |
| Mather Veteran Affairs Medical Center | |
| Mather, California, United States, 95655 | |
| Mercy UC Davis Cancer Center | |
| Merced, California, United States, 95340 | |
| Memorial Medical Center | |
| Modesto, California, United States, 95355 | |
| Kaiser Permanente-Modesto | |
| Modesto, California, United States, 95356 | |
| Palo Alto Medical Foundation-Camino Division | |
| Mountain View, California, United States, 94040 | |
| Palo Alto Medical Foundation-Gynecologic Oncology | |
| Mountain View, California, United States, 94040 | |
| USC Norris Oncology/Hematology-Newport Beach | |
| Newport Beach, California, United States, 92663 | |
| Sutter Cancer Research Consortium | |
| Novato, California, United States, 94945 | |
| Kaiser Permanente-Oakland | |
| Oakland, California, United States, 94611 | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | |
| Orange, California, United States, 92868 | |
| Palo Alto Medical Foundation Health Care | |
| Palo Alto, California, United States, 94301 | |
| Keck Medical Center of USC Pasadena | |
| Pasadena, California, United States, 91105 | |
| PCR Oncology | |
| Pismo Beach, California, United States, 93449 | |
| Kaiser Permanente-Redwood City | |
| Redwood City, California, United States, 94063 | |
| Kaiser Permanente-Richmond | |
| Richmond, California, United States, 94801 | |
| Kaiser Permanente-Roseville | |
| Roseville, California, United States, 95661 | |
| Sutter Roseville Medical Center | |
| Roseville, California, United States, 95661 | |
| Sutter General Hospital | |
| Sacramento, California, United States, 95816 | |
| University of California Davis Comprehensive Cancer Center | |
| Sacramento, California, United States, 95817 | |
| Kaiser Permanente-South Sacramento | |
| Sacramento, California, United States, 95823 | |
| Kaiser Permanente - Sacramento | |
| Sacramento, California, United States, 95825 | |
| California Pacific Medical Center-Pacific Campus | |
| San Francisco, California, United States, 94115 | |
| Kaiser Permanente-San Francisco | |
| San Francisco, California, United States, 94115 | |
| UCSF Medical Center-Mount Zion | |
| San Francisco, California, United States, 94115 | |
| UCSF Medical Center-Mission Bay | |
| San Francisco, California, United States, 94158 | |
| Kaiser Permanente-Santa Teresa-San Jose | |
| San Jose, California, United States, 95119 | |
| Kaiser Permanente San Leandro | |
| San Leandro, California, United States, 94577 | |
| Kaiser Permanente-San Rafael | |
| San Rafael, California, United States, 94903 | |
| Kaiser Permanente Medical Center - Santa Clara | |
| Santa Clara, California, United States, 95051 | |
| Palo Alto Medical Foundation-Santa Cruz | |
| Santa Cruz, California, United States, 95065 | |
| Kaiser Permanente-Santa Rosa | |
| Santa Rosa, California, United States, 95403 | |
| Sutter Pacific Medical Foundation | |
| Santa Rosa, California, United States, 95403 | |
| Kaiser Permanente-South San Francisco | |
| South San Francisco, California, United States, 94080 | |
| Kaiser Permanente-Stockton | |
| Stockton, California, United States, 95210 | |
| Palo Alto Medical Foundation-Sunnyvale | |
| Sunnyvale, California, United States, 94086 | |
| Gene Upshaw Memorial Tahoe Forest Cancer Center | |
| Truckee, California, United States, 96161 | |
| Northbay Cancer Center | |
| Vacaville, California, United States, 95687 | |
| Kaiser Permanente Medical Center-Vacaville | |
| Vacaville, California, United States, 95688 | |
| Kaiser Permanente-Vallejo | |
| Vallejo, California, United States, 94589 | |
| Sutter Solano Medical Center/Cancer Center | |
| Vallejo, California, United States, 94589 | |
| Kaiser Permanente-Walnut Creek | |
| Walnut Creek, California, United States, 94596 | |
| United States, Colorado | |
| Rocky Mountain Cancer Centers-Aurora | |
| Aurora, Colorado, United States, 80012 | |
| The Medical Center of Aurora | |
| Aurora, Colorado, United States, 80012 | |
| University of Colorado Cancer Center - Anschutz Cancer Pavilion | |
| Aurora, Colorado, United States, 80045 | |
| Boulder Community Hospital | |
| Boulder, Colorado, United States, 80301 | |
| Rocky Mountain Cancer Centers-Boulder | |
| Boulder, Colorado, United States, 80304 | |
| Penrose-Saint Francis Healthcare | |
| Colorado Springs, Colorado, United States, 80907 | |
| Rocky Mountain Cancer Centers-Penrose | |
| Colorado Springs, Colorado, United States, 80907 | |
| Porter Adventist Hospital | |
| Denver, Colorado, United States, 80210 | |
| Colorado Blood Cancer Institute | |
| Denver, Colorado, United States, 80218 | |
| Presbyterian - Saint Lukes Medical Center - Health One | |
| Denver, Colorado, United States, 80218 | |
| Rocky Mountain Cancer Centers-Midtown | |
| Denver, Colorado, United States, 80218 | |
| SCL Health Saint Joseph Hospital | |
| Denver, Colorado, United States, 80218 | |
| Rocky Mountain Cancer Centers-Rose | |
| Denver, Colorado, United States, 80220 | |
| Rose Medical Center | |
| Denver, Colorado, United States, 80220 | |
| Colorado Cancer Research Program NCORP | |
| Denver, Colorado, United States, 80222 | |
| Mercy Medical Center | |
| Durango, Colorado, United States, 81301 | |
| Southwest Oncology PC | |
| Durango, Colorado, United States, 81301 | |
| Comprehensive Cancer Care and Research Institute of Colorado LLC | |
| Englewood, Colorado, United States, 80113 | |
| Swedish Medical Center | |
| Englewood, Colorado, United States, 80113 | |
| Mountain Blue Cancer Care Center | |
| Golden, Colorado, United States, 80401 | |
| North Colorado Medical Center | |
| Greeley, Colorado, United States, 80631 | |
| Rocky Mountain Cancer Centers-Greenwood Village | |
| Greenwood Village, Colorado, United States, 80111 | |
| Rocky Mountain Cancer Centers-Lakewood | |
| Lakewood, Colorado, United States, 80228 | |
| Saint Anthony Hospital | |
| Lakewood, Colorado, United States, 80228 | |
| Rocky Mountain Cancer Centers-Littleton | |
| Littleton, Colorado, United States, 80120 | |
| Littleton Adventist Hospital | |
| Littleton, Colorado, United States, 80122 | |
| Rocky Mountain Cancer Centers-Sky Ridge | |
| Lone Tree, Colorado, United States, 80124 | |
| Sky Ridge Medical Center | |
| Lone Tree, Colorado, United States, 80124 | |
| Longmont United Hospital | |
| Longmont, Colorado, United States, 80501 | |
| Rocky Mountain Cancer Centers-Longmont | |
| Longmont, Colorado, United States, 80501 | |
| McKee Medical Center | |
| Loveland, Colorado, United States, 80539 | |
| Parker Adventist Hospital | |
| Parker, Colorado, United States, 80138 | |
| Rocky Mountain Cancer Centers-Parker | |
| Parker, Colorado, United States, 80138 | |
| Saint Mary Corwin Medical Center | |
| Pueblo, Colorado, United States, 81004 | |
| Rocky Mountain Cancer Centers - Pueblo | |
| Pueblo, Colorado, United States, 81008 | |
| Rocky Mountain Cancer Centers-Thornton | |
| Thornton, Colorado, United States, 80260 | |
| SCL Health Lutheran Medical Center | |
| Wheat Ridge, Colorado, United States, 80033 | |
| United States, Connecticut | |
| Greenwich Hospital | |
| Greenwich, Connecticut, United States, 06830 | |
| Yale University | |
| New Haven, Connecticut, United States, 06520 | |
| Eastern Connecticut Hematology and Oncology Associates | |
| Norwich, Connecticut, United States, 06360 | |
| Stamford Hospital/Bennett Cancer Center | |
| Stamford, Connecticut, United States, 06904 | |
| United States, Delaware | |
| Beebe Medical Center | |
| Lewes, Delaware, United States, 19958 | |
| Medical Oncology Hematology Consultants PA | |
| Newark, Delaware, United States, 19713 | |
| Regional Hematology and Oncology PA | |
| Newark, Delaware, United States, 19713 | |
| Christiana Care Health System-Christiana Hospital | |
| Newark, Delaware, United States, 19718 | |
| Nanticoke Memorial Hospital | |
| Seaford, Delaware, United States, 19973 | |
| United States, District of Columbia | |
| MedStar Georgetown University Hospital | |
| Washington, D.C., District of Columbia, United States, 20007 | |
| MedStar Washington Hospital Center | |
| Washington, D.C., District of Columbia, United States, 20010 | |
| Sibley Memorial Hospital | |
| Washington, D.C., District of Columbia, United States, 20016 | |
| George Washington University Medical Center | |
| Washington, D.C., District of Columbia, United States, 20037 | |
| Veterans Affairs Medical Center -Washington DC | |
| Washington, D.C., District of Columbia, United States, 20422 | |
| United States, Florida | |
| Broward Health Medical Center | |
| Fort Lauderdale, Florida, United States, 33316 | |
| Lakeland Regional Health Hollis Cancer Center | |
| Lakeland, Florida, United States, 33805 | |
| Florida Hospital Orlando | |
| Orlando, Florida, United States, 32803 | |
| UF Cancer Center at Orlando Health | |
| Orlando, Florida, United States, 32806 | |
| Moffitt Cancer Center | |
| Tampa, Florida, United States, 33612 | |
| United States, Georgia | |
| John B Amos Cancer Center | |
| Columbus, Georgia, United States, 31904 | |
| Atlanta VA Medical Center | |
| Decatur, Georgia, United States, 30033 | |
| Northeast Georgia Medical Center-Gainesville | |
| Gainesville, Georgia, United States, 30501 | |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | |
| Savannah, Georgia, United States, 31405 | |
| United States, Hawaii | |
| Hawaii Oncology Inc-Pali Momi | |
| 'Aiea, Hawaii, United States, 96701 | |
| Hawaii Cancer Care Inc-POB II | |
| Honolulu, Hawaii, United States, 96813 | |
| Queen's Medical Center | |
| Honolulu, Hawaii, United States, 96813 | |
| University of Hawaii Cancer Center | |
| Honolulu, Hawaii, United States, 96813 | |
| Hawaii Cancer Care Inc-Liliha | |
| Honolulu, Hawaii, United States, 96817 | |
| Hawaii Oncology Inc-Kuakini | |
| Honolulu, Hawaii, United States, 96817 | |
| Kaiser Permanente Moanalua Medical Center | |
| Honolulu, Hawaii, United States, 96819 | |
| Tripler Army Medical Center | |
| Honolulu, Hawaii, United States, 96859 | |
| United States, Idaho | |
| Saint Alphonsus Cancer Care Center-Boise | |
| Boise, Idaho, United States, 83706 | |
| Kootenai Medical Center | |
| Coeur d'Alene, Idaho, United States, 83814 | |
| Kootenai Cancer Center | |
| Post Falls, Idaho, United States, 83854 | |
| Kootenai Cancer Clinic | |
| Sandpoint, Idaho, United States, 83864 | |
| United States, Illinois | |
| Rush - Copley Medical Center | |
| Aurora, Illinois, United States, 60504 | |
| Saint Joseph Medical Center | |
| Bloomington, Illinois, United States, 61701 | |
| Illinois CancerCare-Bloomington | |
| Bloomington, Illinois, United States, 61704 | |
| Illinois CancerCare-Canton | |
| Canton, Illinois, United States, 61520 | |
| Illinois CancerCare-Carthage | |
| Carthage, Illinois, United States, 62321 | |
| Centralia Oncology Clinic | |
| Centralia, Illinois, United States, 62801 | |
| Mount Sinai Hospital Medical Center | |
| Chicago, Illinois, United States, 60608 | |
| Northwestern University | |
| Chicago, Illinois, United States, 60611 | |
| University of Chicago Comprehensive Cancer Center | |
| Chicago, Illinois, United States, 60637 | |
| Weiss Memorial Hospital | |
| Chicago, Illinois, United States, 60640 | |
| Presence Saint Joseph Hospital-Chicago | |
| Chicago, Illinois, United States, 60657 | |
| Cancer Care Center of Decatur | |
| Decatur, Illinois, United States, 62526 | |
| Decatur Memorial Hospital | |
| Decatur, Illinois, United States, 62526 | |
| Heartland Cancer Research NCORP | |
| Decatur, Illinois, United States, 62526 | |
| Crossroads Cancer Center | |
| Effingham, Illinois, United States, 62401 | |
| Illinois CancerCare-Eureka | |
| Eureka, Illinois, United States, 61530 | |
| NorthShore University HealthSystem-Evanston Hospital | |
| Evanston, Illinois, United States, 60201 | |
| Illinois CancerCare-Galesburg | |
| Galesburg, Illinois, United States, 61401 | |
| Northwestern Medicine Cancer Center Delnor | |
| Geneva, Illinois, United States, 60134 | |
| NorthShore University HealthSystem-Glenbrook Hospital | |
| Glenview, Illinois, United States, 60026 | |
| NorthShore University HealthSystem-Highland Park Hospital | |
| Highland Park, Illinois, United States, 60035 | |
| Hines Veterans Administration Hospital | |
| Hines, Illinois, United States, 60141 | |
| Joliet Oncology-Hematology Associates Limited | |
| Joliet, Illinois, United States, 60435 | |
| Presence Saint Mary's Hospital | |
| Kankakee, Illinois, United States, 60901 | |
| Illinois CancerCare-Kewanee Clinic | |
| Kewanee, Illinois, United States, 61443 | |
| Illinois CancerCare-Macomb | |
| Macomb, Illinois, United States, 61455 | |
| Loyola University Medical Center | |
| Maywood, Illinois, United States, 60153 | |
| Trinity Medical Center | |
| Moline, Illinois, United States, 61265 | |
| Illinois CancerCare-Monmouth | |
| Monmouth, Illinois, United States, 61462 | |
| Community Cancer Center Foundation | |
| Normal, Illinois, United States, 61761 | |
| Illinois CancerCare-Ottawa Clinic | |
| Ottawa, Illinois, United States, 61350 | |
| Ottawa Regional Hospital and Healthcare Center | |
| Ottawa, Illinois, United States, 61350 | |
| Illinois CancerCare-Pekin | |
| Pekin, Illinois, United States, 61554 | |
| OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center | |
| Pekin, Illinois, United States, 61554 | |
| Methodist Medical Center of Illinois | |
| Peoria, Illinois, United States, 61603 | |
| Proctor Hospital | |
| Peoria, Illinois, United States, 61614 | |
| Illinois CancerCare-Peoria | |
| Peoria, Illinois, United States, 61615 | |
| OSF Saint Francis Medical Center | |
| Peoria, Illinois, United States, 61637 | |
| Illinois CancerCare-Peru | |
| Peru, Illinois, United States, 61354 | |
| Illinois CancerCare-Princeton | |
| Princeton, Illinois, United States, 61356 | |
| West Suburban Medical Center | |
| River Forest, Illinois, United States, 60305 | |
| SwedishAmerican Regional Cancer Center/ACT | |
| Rockford, Illinois, United States, 61114 | |
| Southern Illinois University School of Medicine | |
| Springfield, Illinois, United States, 62702 | |
| Springfield Clinic | |
| Springfield, Illinois, United States, 62702 | |
| Memorial Medical Center | |
| Springfield, Illinois, United States, 62781 | |
| Cancer Care Specialists of Illinois-Swansea | |
| Swansea, Illinois, United States, 62226 | |
| Carle Cancer Center | |
| Urbana, Illinois, United States, 61801 | |
| Northwestern Medicine Cancer Center Warrenville | |
| Warrenville, Illinois, United States, 60555 | |
| Rush-Copley Healthcare Center | |
| Yorkville, Illinois, United States, 60560 | |
| United States, Indiana | |
| IU Health Bloomington | |
| Bloomington, Indiana, United States, 47403 | |
| Memorial Regional Cancer Center Day Road | |
| Mishawaka, Indiana, United States, 46545 | |
| Memorial Hospital of South Bend | |
| South Bend, Indiana, United States, 46601 | |
| Porter Memorial Hospital | |
| Valparaiso, Indiana, United States, 46383 | |
| United States, Iowa | |
| McFarland Clinic PC-William R Bliss Cancer Center | |
| Ames, Iowa, United States, 50010 | |
| Mercy Hospital | |
| Cedar Rapids, Iowa, United States, 52403 | |
| Oncology Associates at Mercy Medical Center | |
| Cedar Rapids, Iowa, United States, 52403 | |
| Medical Oncology and Hematology Associates-West Des Moines | |
| Clive, Iowa, United States, 50325 | |
| Alegent Health Mercy Hospital | |
| Council Bluffs, Iowa, United States, 51503 | |
| Genesis Medical Center - East Campus | |
| Davenport, Iowa, United States, 52803 | |
| Medical Oncology and Hematology Associates-Laurel | |
| Des Moines, Iowa, United States, 50314 | |
| Mercy Medical Center - Des Moines | |
| Des Moines, Iowa, United States, 50314 | |
| University of Iowa/Holden Comprehensive Cancer Center | |
| Iowa City, Iowa, United States, 52242 | |
| Iowa City VA Healthcare System | |
| Iowa City, Iowa, United States, 52246 | |
| United States, Kansas | |
| Cancer Center of Kansas - Chanute | |
| Chanute, Kansas, United States, 66720 | |
| Cancer Center of Kansas - Dodge City | |
| Dodge City, Kansas, United States, 67801 | |
| Cancer Center of Kansas - El Dorado | |
| El Dorado, Kansas, United States, 67042 | |
| Cancer Center of Kansas - Fort Scott | |
| Fort Scott, Kansas, United States, 66701 | |
| Saint Catherine Hospital | |
| Garden City, Kansas, United States, 67846 | |
| Heartland Cancer Center | |
| Great Bend, Kansas, United States, 67530 | |
| Saint Rose Ambulatory and Surgery Center | |
| Great Bend, Kansas, United States, 67530 | |
| Hays Medical Center | |
| Hays, Kansas, United States, 67601 | |
| Cancer Center of Kansas-Independence | |
| Independence, Kansas, United States, 67301 | |
| University of Kansas Cancer Center-West | |
| Kansas City, Kansas, United States, 66112 | |
| University of Kansas Cancer Center | |
| Kansas City, Kansas, United States, 66160 | |
| Cancer Center of Kansas-Kingman | |
| Kingman, Kansas, United States, 67068 | |
| Lawrence Memorial Hospital | |
| Lawrence, Kansas, United States, 66044 | |
| Cancer Center of Kansas-Liberal | |
| Liberal, Kansas, United States, 67905 | |
| Cancer Center of Kansas-Manhattan | |
| Manhattan, Kansas, United States, 66502 | |
| Cancer Center of Kansas - McPherson | |
| McPherson, Kansas, United States, 67460 | |
| Cancer Center of Kansas - Newton | |
| Newton, Kansas, United States, 67114 | |
| Olathe Medical Center | |
| Olathe, Kansas, United States, 66061 | |
| Menorah Medical Center | |
| Overland Park, Kansas, United States, 66209 | |
| University of Kansas Cancer Center-Overland Park | |
| Overland Park, Kansas, United States, 66210 | |
| Cancer Center of Kansas - Parsons | |
| Parsons, Kansas, United States, 67357 | |
| Cancer Center of Kansas - Pratt | |
| Pratt, Kansas, United States, 67124 | |
| Cancer Center of Kansas - Salina | |
| Salina, Kansas, United States, 67401 | |
| Salina Regional Health Center | |
| Salina, Kansas, United States, 67401 | |
| Cotton O'Neil Cancer Center / Stormont Vail Health | |
| Topeka, Kansas, United States, 66606 | |
| Saint Francis Hospital and Medical Center - Topeka | |
| Topeka, Kansas, United States, 66606 | |
| Topeka VA Hospital | |
| Topeka, Kansas, United States, 66622 | |
| Cancer Center of Kansas - Wellington | |
| Wellington, Kansas, United States, 67152 | |
| Associates In Womens Health | |
| Wichita, Kansas, United States, 67208 | |
| Cancer Center of Kansas-Wichita Medical Arts Tower | |
| Wichita, Kansas, United States, 67208 | |
| Cancer Center of Kansas - Wichita | |
| Wichita, Kansas, United States, 67214 | |
| Via Christi Regional Medical Center | |
| Wichita, Kansas, United States, 67214 | |
| Wichita NCI Community Oncology Research Program | |
| Wichita, Kansas, United States, 67214 | |
| Cancer Center of Kansas - Winfield | |
| Winfield, Kansas, United States, 67156 | |
| United States, Kentucky | |
| University of Kentucky/Markey Cancer Center | |
| Lexington, Kentucky, United States, 40536 | |
| United States, Louisiana | |
| Hematology/Oncology Clinic LLP | |
| Baton Rouge, Louisiana, United States, 70809 | |
| Ochsner Health Center-Summa | |
| Baton Rouge, Louisiana, United States, 70809 | |
| Ochsner Medical Center Kenner | |
| Kenner, Louisiana, United States, 70065 | |
| East Jefferson General Hospital | |
| Metairie, Louisiana, United States, 70006 | |
| Louisiana State University Health Science Center | |
| New Orleans, Louisiana, United States, 70112 | |
| Tulane University Health Sciences Center | |
| New Orleans, Louisiana, United States, 70112 | |
| University Medical Center New Orleans | |
| New Orleans, Louisiana, United States, 70112 | |
| Ochsner Medical Center Jefferson | |
| New Orleans, Louisiana, United States, 70121 | |
| United States, Maine | |
| Harold Alfond Center for Cancer Care | |
| Augusta, Maine, United States, 04330 | |
| Eastern Maine Medical Center | |
| Bangor, Maine, United States, 04401 | |
| Penobscot Bay Medical Center | |
| Rockport, Maine, United States, 04856 | |
| United States, Maryland | |
| Johns Hopkins University/Sidney Kimmel Cancer Center | |
| Baltimore, Maryland, United States, 21287 | |
| Montgomery General Hospital-Olney | |
| Olney, Maryland, United States, 20832 | |
| United States, Massachusetts | |
| Boston Medical Center | |
| Boston, Massachusetts, United States, 02118 | |
| Dana-Farber Cancer Institute | |
| Boston, Massachusetts, United States, 02215 | |
| Steward Saint Elizabeth's Medical Center | |
| Brighton, Massachusetts, United States, 02135 | |
| Lahey Hospital and Medical Center | |
| Burlington, Massachusetts, United States, 01805 | |
| Dana Farber Community Cancer Care-Quincy | |
| Quincy, Massachusetts, United States, 02169 | |
| United States, Michigan | |
| Hickman Cancer Center | |
| Adrian, Michigan, United States, 49221 | |
| Saint Joseph Mercy Hospital | |
| Ann Arbor, Michigan, United States, 48106-0995 | |
| Michigan Cancer Research Consortium NCORP | |
| Ann Arbor, Michigan, United States, 48106 | |
| University of Michigan Comprehensive Cancer Center | |
| Ann Arbor, Michigan, United States, 48109 | |
| Bronson Battle Creek | |
| Battle Creek, Michigan, United States, 49017 | |
| IHA Hematology Oncology Consultants-Brighton | |
| Brighton, Michigan, United States, 48114 | |
| Saint Joseph Mercy Brighton | |
| Brighton, Michigan, United States, 48114 | |
| IHA Hematology Oncology Consultants-Canton | |
| Canton, Michigan, United States, 48188 | |
| Saint Joseph Mercy Canton Health Center | |
| Canton, Michigan, United States, 48188 | |
| IHA Hematology Oncology Consultants-Chelsea | |
| Chelsea, Michigan, United States, 48118 | |
| Saint Joseph Mercy Chelsea | |
| Chelsea, Michigan, United States, 48118 | |
| Saint John Hospital and Medical Center | |
| Detroit, Michigan, United States, 48236 | |
| Green Bay Oncology - Escanaba | |
| Escanaba, Michigan, United States, 49829 | |
| Botsford General Hospital | |
| Farmington, Michigan, United States, 48334 | |
| Cancer Research Consortium of West Michigan NCORP | |
| Grand Rapids, Michigan, United States, 49503 | |
| Mercy Health Saint Mary's | |
| Grand Rapids, Michigan, United States, 49503 | |
| Spectrum Health at Butterworth Campus | |
| Grand Rapids, Michigan, United States, 49503 | |
| Green Bay Oncology - Iron Mountain | |
| Iron Mountain, Michigan, United States, 49801 | |
| West Michigan Cancer Center | |
| Kalamazoo, Michigan, United States, 49007 | |
| Sparrow Hospital | |
| Lansing, Michigan, United States, 48912 | |
| Mercy Health Mercy Campus | |
| Muskegon, Michigan, United States, 49444 | |
| Lakeland Community Hospital | |
| Niles, Michigan, United States, 49120 | |
| Saint Joseph Mercy Oakland | |
| Pontiac, Michigan, United States, 48341 | |
| Lake Huron Medical Center | |
| Port Huron, Michigan, United States, 48060 | |
| Spectrum Health Reed City Hospital | |
| Reed City, Michigan, United States, 49677 | |
| William Beaumont Hospital-Royal Oak | |
| Royal Oak, Michigan, United States, 48073 | |
| Saint Mary's of Michigan | |
| Saginaw, Michigan, United States, 48601 | |
| Marie Yeager Cancer Center | |
| Saint Joseph, Michigan, United States, 49085 | |
| Munson Medical Center | |
| Traverse City, Michigan, United States, 49684 | |
| William Beaumont Hospital - Troy | |
| Troy, Michigan, United States, 48098 | |
| Saint John Macomb-Oakland Hospital | |
| Warren, Michigan, United States, 48093 | |
| IHA Hematology Oncology Consultants-Ann Arbor | |
| Ypsilanti, Michigan, United States, 48197 | |
| United States, Minnesota | |
| Sanford Clinic North-Bemidgi | |
| Bemidji, Minnesota, United States, 56601 | |
| Fairview Ridges Hospital | |
| Burnsville, Minnesota, United States, 55337 | |
| Mercy Hospital | |
| Coon Rapids, Minnesota, United States, 55433 | |
| Essentia Health Cancer Center | |
| Duluth, Minnesota, United States, 55805 | |
| Fairview-Southdale Hospital | |
| Edina, Minnesota, United States, 55435 | |
| Lake Region Healthcare Corporation-Cancer Care | |
| Fergus Falls, Minnesota, United States, 56537 | |
| Unity Hospital | |
| Fridley, Minnesota, United States, 55432 | |
| Minnesota Oncology Hematology PA-Maplewood | |
| Maplewood, Minnesota, United States, 55109 | |
| Saint John's Hospital - Healtheast | |
| Maplewood, Minnesota, United States, 55109 | |
| Abbott-Northwestern Hospital | |
| Minneapolis, Minnesota, United States, 55407 | |
| Hennepin County Medical Center | |
| Minneapolis, Minnesota, United States, 55415 | |
| Minneapolis Veterans Medical Center | |
| Minneapolis, Minnesota, United States, 55417 | |
| Health Partners Inc | |
| Minneapolis, Minnesota, United States, 55454 | |
| University of Minnesota/Masonic Cancer Center | |
| Minneapolis, Minnesota, United States, 55455 | |
| North Memorial Medical Health Center | |
| Robbinsdale, Minnesota, United States, 55422 | |
| Mayo Clinic | |
| Rochester, Minnesota, United States, 55905 | |
| Coborn Cancer Center at Saint Cloud Hospital | |
| Saint Cloud, Minnesota, United States, 56303 | |
| Metro Minnesota Community Oncology Research Consortium | |
| Saint Louis Park, Minnesota, United States, 55416 | |
| Park Nicollet Clinic - Saint Louis Park | |
| Saint Louis Park, Minnesota, United States, 55416 | |
| Regions Hospital | |
| Saint Paul, Minnesota, United States, 55101 | |
| United Hospital | |
| Saint Paul, Minnesota, United States, 55102 | |
| Saint Francis Regional Medical Center | |
| Shakopee, Minnesota, United States, 55379 | |
| Lakeview Hospital | |
| Stillwater, Minnesota, United States, 55082 | |
| Ridgeview Medical Center | |
| Waconia, Minnesota, United States, 55387 | |
| Rice Memorial Hospital | |
| Willmar, Minnesota, United States, 56201 | |
| Minnesota Oncology Hematology PA-Woodbury | |
| Woodbury, Minnesota, United States, 55125 | |
| United States, Mississippi | |
| University of Mississippi Medical Center | |
| Jackson, Mississippi, United States, 39216 | |
| United States, Missouri | |
| Saint Francis Medical Center | |
| Cape Girardeau, Missouri, United States, 63703 | |
| Southeast Cancer Center | |
| Cape Girardeau, Missouri, United States, 63703 | |
| University of Missouri - Ellis Fischel | |
| Columbia, Missouri, United States, 65212 | |
| Barnes-Jewish West County Hospital | |
| Creve Coeur, Missouri, United States, 63141 | |
| Mercy Hospital-Joplin | |
| Joplin, Missouri, United States, 64804 | |
| Truman Medical Center | |
| Kansas City, Missouri, United States, 64108 | |
| Saint Luke's Hospital of Kansas City | |
| Kansas City, Missouri, United States, 64111 | |
| Kansas City Veterans Affairs Medical Center | |
| Kansas City, Missouri, United States, 64128 | |
| The University of Kansas Cancer Center-South | |
| Kansas City, Missouri, United States, 64131 | |
| Research Medical Center | |
| Kansas City, Missouri, United States, 64132 | |
| The University of Kansas Cancer Center-North | |
| Kansas City, Missouri, United States, 64154 | |
| The University of Kansas Cancer Center-Lee's Summit | |
| Lee's Summit, Missouri, United States, 64064 | |
| Delbert Day Cancer Institute at PCRMC | |
| Rolla, Missouri, United States, 65401 | |
| Heartland Regional Medical Center | |
| Saint Joseph, Missouri, United States, 64506 | |
| Saint Louis Cancer and Breast Institute-South City | |
| Saint Louis, Missouri, United States, 63109 | |
| Washington University School of Medicine | |
| Saint Louis, Missouri, United States, 63110 | |
| Missouri Baptist Medical Center | |
| Saint Louis, Missouri, United States, 63131 | |
| Mercy Hospital Saint Louis | |
| Saint Louis, Missouri, United States, 63141 | |
| Siteman Cancer Center - Saint Peters | |
| Saint Peters, Missouri, United States, 63376 | |
| Mercy Hospital Springfield | |
| Springfield, Missouri, United States, 65804 | |
| CoxHealth South Hospital | |
| Springfield, Missouri, United States, 65807 | |
| United States, Montana | |
| Billings Clinic Cancer Center | |
| Billings, Montana, United States, 59101 | |
| Saint Vincent Healthcare | |
| Billings, Montana, United States, 59101 | |
| Montana Cancer Consortium NCORP | |
| Billings, Montana, United States, 59102 | |
| Bozeman Deaconess Hospital | |
| Bozeman, Montana, United States, 59715 | |
| Benefis Healthcare- Sletten Cancer Institute | |
| Great Falls, Montana, United States, 59405 | |
| United States, Nebraska | |
| CHI Health Saint Francis | |
| Grand Island, Nebraska, United States, 68803 | |
| CHI Health Good Samaritan | |
| Kearney, Nebraska, United States, 68847 | |
| Nebraska Methodist Hospital | |
| Omaha, Nebraska, United States, 68114 | |
| Alegent Health Immanuel Medical Center | |
| Omaha, Nebraska, United States, 68122 | |
| Alegent Health Bergan Mercy Medical Center | |
| Omaha, Nebraska, United States, 68124 | |
| Alegent Health Lakeside Hospital | |
| Omaha, Nebraska, United States, 68130 | |
| Creighton University Medical Center | |
| Omaha, Nebraska, United States, 68131 | |
| United States, Nevada | |
| Nevada Cancer Research Foundation CCOP | |
| Las Vegas, Nevada, United States, 89106 | |
| Comprehensive Cancer Centers of Nevada | |
| Las Vegas, Nevada, United States, 89148 | |
| Comprehensive Cancer Centers of Nevada - Central Valley | |
| Las Vegas, Nevada, United States, 89169 | |
| Renown Regional Medical Center | |
| Reno, Nevada, United States, 89502 | |
| United States, New Hampshire | |
| New Hampshire Oncology Hematology PA-Concord | |
| Concord, New Hampshire, United States, 03301 | |
| New Hampshire Oncology Hematology PA-Hooksett | |
| Hooksett, New Hampshire, United States, 03106 | |
| LRGHealthcare-Lakes Region General Hospital | |
| Laconia, New Hampshire, United States, 03246 | |
| United States, New Jersey | |
| Veterans Adminstration New Jersey Health Care System | |
| East Orange, New Jersey, United States, 07018-1095 | |
| Rutgers Cancer Institute of New Jersey | |
| New Brunswick, New Jersey, United States, 08903 | |
| Sparta Cancer Treatment Center | |
| Sparta, New Jersey, United States, 07871 | |
| United States, New Mexico | |
| Lovelace Medical Center-Downtown | |
| Albuquerque, New Mexico, United States, 87102 | |
| University of New Mexico Cancer Center | |
| Albuquerque, New Mexico, United States, 87102 | |
| Hematology Oncology Associates | |
| Albuquerque, New Mexico, United States, 87106 | |
| Memorial Medical Center - Las Cruces | |
| Las Cruces, New Mexico, United States, 88011 | |
| Christus Saint Vincent Regional Cancer Center | |
| Santa Fe, New Mexico, United States, 87505 | |
| United States, New York | |
| Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus | |
| Brooklyn, New York, United States, 11209 | |
| Veterans Affairs Western New York Health Care System-Buffalo | |
| Buffalo, New York, United States, 14215 | |
| Roswell Park Cancer Institute | |
| Buffalo, New York, United States, 14263 | |
| Hematology Oncology Associates of Central New York-East Syracuse | |
| East Syracuse, New York, United States, 13057 | |
| Arnot Ogden Medical Center/Falck Cancer Center | |
| Elmira, New York, United States, 14905 | |
| Glens Falls Hospital | |
| Glens Falls, New York, United States, 12801 | |
| Orange Regional Medical Center | |
| Middletown, New York, United States, 10940 | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | |
| New York, New York, United States, 10016 | |
| Columbia University/Herbert Irving Cancer Center | |
| New York, New York, United States, 10032 | |
| Weill Medical College of Cornell University | |
| New York, New York, United States, 10065 | |
| University of Rochester | |
| Rochester, New York, United States, 14642 | |
| State University of New York Upstate Medical University | |
| Syracuse, New York, United States, 13210 | |
| Montefiore Medical Center-Weiler Hospital | |
| The Bronx, New York, United States, 10461 | |
| Montefiore Medical Center - Moses Campus | |
| The Bronx, New York, United States, 10467-2490 | |
| Dickstein Cancer Treatment Center | |
| White Plains, New York, United States, 10601 | |
| United States, North Carolina | |
| Mission Hospital-Memorial Campus | |
| Asheville, North Carolina, United States, 28801 | |
| Carolinas Medical Center/Levine Cancer Institute | |
| Charlotte, North Carolina, United States, 28203 | |
| Carolinas HealthCare System NorthEast | |
| Concord, North Carolina, United States, 28025 | |
| Hendersonville Hematology and Oncology at Pardee | |
| Hendersonville, North Carolina, United States, 28791 | |
| Margaret R Pardee Memorial Hospital | |
| Hendersonville, North Carolina, United States, 28791 | |
| Park Ridge Hospital Breast Health Center | |
| Hendersonville, North Carolina, United States, 28792 | |
| Kinston Medical Specialists PA | |
| Kinston, North Carolina, United States, 28501 | |
| Carolinas HealthCare System Union | |
| Monroe, North Carolina, United States, 28112 | |
| Carolinas HealthCare System Cleveland | |
| Shelby, North Carolina, United States, 28150 | |
| Iredell Memorial Hospital | |
| Statesville, North Carolina, United States, 28677 | |
| Southeast Clinical Oncology Research (SCOR) Consortium NCORP | |
| Winston-Salem, North Carolina, United States, 27104 | |
| United States, North Dakota | |
| Sanford Bismarck Medical Center | |
| Bismarck, North Dakota, United States, 58501 | |
| Roger Maris Cancer Center | |
| Fargo, North Dakota, United States, 58122 | |
| Sanford Clinic North-Fargo | |
| Fargo, North Dakota, United States, 58122 | |
| Sanford Medical Center-Fargo | |
| Fargo, North Dakota, United States, 58122 | |
| United States, Ohio | |
| Summa Akron City Hospital/Cooper Cancer Center | |
| Akron, Ohio, United States, 44304 | |
| Summa Barberton Hospital | |
| Barberton, Ohio, United States, 44203 | |
| Adena Regional Medical Center | |
| Chillicothe, Ohio, United States, 45601 | |
| The Christ Hospital | |
| Cincinnati, Ohio, United States, 45219 | |
| University of Cincinnati/Barrett Cancer Center | |
| Cincinnati, Ohio, United States, 45219 | |
| MetroHealth Medical Center | |
| Cleveland, Ohio, United States, 44109 | |
| Ohio State University Comprehensive Cancer Center | |
| Columbus, Ohio, United States, 43210 | |
| Columbus Oncology and Hematology Associates Inc | |
| Columbus, Ohio, United States, 43214 | |
| Riverside Methodist Hospital | |
| Columbus, Ohio, United States, 43214 | |
| Columbus NCI Community Oncology Research Program | |
| Columbus, Ohio, United States, 43215 | |
| Grant Medical Center | |
| Columbus, Ohio, United States, 43215 | |
| The Mark H Zangmeister Center | |
| Columbus, Ohio, United States, 43219 | |
| Mount Carmel Health Center West | |
| Columbus, Ohio, United States, 43222 | |
| Good Samaritan Hospital - Dayton | |
| Dayton, Ohio, United States, 45406 | |
| Miami Valley Hospital | |
| Dayton, Ohio, United States, 45409 | |
| Samaritan North Health Center | |
| Dayton, Ohio, United States, 45415 | |
| Dayton NCI Community Oncology Research Program | |
| Dayton, Ohio, United States, 45420 | |
| Veteran Affairs Medical Center | |
| Dayton, Ohio, United States, 45428 | |
| Delaware Health Center-Grady Cancer Center | |
| Delaware, Ohio, United States, 43015 | |
| Armes Family Cancer Center | |
| Findlay, Ohio, United States, 45840 | |
| Orion Cancer Care | |
| Findlay, Ohio, United States, 45840 | |
| Atrium Medical Center-Middletown Regional Hospital | |
| Franklin, Ohio, United States, 45005-1066 | |
| Dayton Physicians LLC-Atrium | |
| Franklin, Ohio, United States, 45005 | |
| Kettering Medical Center | |
| Kettering, Ohio, United States, 45429 | |
| Saint Rita's Medical Center | |
| Lima, Ohio, United States, 45801 | |
| Marietta Memorial Hospital | |
| Marietta, Ohio, United States, 45750 | |
| Toledo Clinic Cancer Centers-Maumee | |
| Maumee, Ohio, United States, 43537 | |
| Saint Charles Hospital | |
| Oregon, Ohio, United States, 43616 | |
| Mercy Health Perrysburg Cancer Center | |
| Perrysburg, Ohio, United States, 43551 | |
| Southern Ohio Medical Center | |
| Portsmouth, Ohio, United States, 45662 | |
| Springfield Regional Medical Center | |
| Springfield, Ohio, United States, 45505 | |
| Mercy Saint Anne Hospital | |
| Toledo, Ohio, United States, 43623 | |
| Toledo Clinic Cancer Centers-Toledo | |
| Toledo, Ohio, United States, 43623 | |
| Upper Valley Medical Center | |
| Troy, Ohio, United States, 45373 | |
| Saint Ann's Hospital | |
| Westerville, Ohio, United States, 43081 | |
| Wright-Patterson Medical Center | |
| Wright-Patterson Air Force Base, Ohio, United States, 45433-5529 | |
| United States, Oklahoma | |
| University of Oklahoma Health Sciences Center | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| Oklahoma Cancer Specialists and Research Institute-Tulsa | |
| Tulsa, Oklahoma, United States, 74146 | |
| United States, Oregon | |
| Legacy Mount Hood Medical Center | |
| Gresham, Oregon, United States, 97030 | |
| Legacy Good Samaritan Hospital and Medical Center | |
| Portland, Oregon, United States, 97210 | |
| Kaiser Permanente Northwest | |
| Portland, Oregon, United States, 97227 | |
| Oregon Health and Science University | |
| Portland, Oregon, United States, 97239 | |
| Portland Veterans Administration Medical Center | |
| Portland, Oregon, United States, 97239 | |
| Legacy Meridian Park Hospital | |
| Tualatin, Oregon, United States, 97062 | |
| United States, Pennsylvania | |
| Lehigh Valley Hospital-Cedar Crest | |
| Allentown, Pennsylvania, United States, 18103 | |
| Lehigh Valley Hospital - Muhlenberg | |
| Bethlehem, Pennsylvania, United States, 18017 | |
| Doylestown Hospital | |
| Doylestown, Pennsylvania, United States, 18901 | |
| Penn State Milton S Hershey Medical Center | |
| Hershey, Pennsylvania, United States, 17033-0850 | |
| Thomas Jefferson University Hospital | |
| Philadelphia, Pennsylvania, United States, 19107 | |
| Fox Chase Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19111 | |
| Temple University Hospital | |
| Philadelphia, Pennsylvania, United States, 19140 | |
| Hematology and Oncology Associates of North East Pennsylvania | |
| Scranton, Pennsylvania, United States, 18508 | |
| Reading Hospital | |
| West Reading, Pennsylvania, United States, 19611 | |
| United States, South Carolina | |
| AnMed Health Cancer Center | |
| Anderson, South Carolina, United States, 29621 | |
| Roper Hospital | |
| Charleston, South Carolina, United States, 29401 | |
| Charleston Hematology Oncology Associates-Roper | |
| Charleston, South Carolina, United States, 29403 | |
| Charleston Hematology Oncology Associates PA-St. Francis | |
| Charleston, South Carolina, United States, 29414 | |
| Medical University of South Carolina | |
| Charleston, South Carolina, United States, 29425 | |
| Greenville Health System Cancer Institute-Easley | |
| Easley, South Carolina, United States, 29640 | |
| Saint Francis Hospital | |
| Greenville, South Carolina, United States, 29601 | |
| Greenville Health System Cancer Institute-Butternut | |
| Greenville, South Carolina, United States, 29605 | |
| Greenville Health System Cancer Institute-Faris | |
| Greenville, South Carolina, United States, 29605 | |
| Greenville Memorial Hospital | |
| Greenville, South Carolina, United States, 29605 | |
| Saint Francis Cancer Center | |
| Greenville, South Carolina, United States, 29607 | |
| Greenville Health System Cancer Institute-Eastside | |
| Greenville, South Carolina, United States, 29615 | |
| Self Regional Healthcare | |
| Greenwood, South Carolina, United States, 29646 | |
| Greenville Health System Cancer Institute-Greer | |
| Greer, South Carolina, United States, 29650 | |
| Greenville Health System Cancer Institute-Seneca | |
| Seneca, South Carolina, United States, 29672 | |
| Spartanburg Medical Center | |
| Spartanburg, South Carolina, United States, 29303 | |
| Greenville Health System Cancer Institute-Spartanburg | |
| Spartanburg, South Carolina, United States, 29307 | |
| United States, South Dakota | |
| Sanford Cancer Center-Oncology Clinic | |
| Sioux Falls, South Dakota, United States, 57104 | |
| Sanford USD Medical Center - Sioux Falls | |
| Sioux Falls, South Dakota, United States, 57117-5134 | |
| United States, Tennessee | |
| University of Tennessee - Knoxville | |
| Knoxville, Tennessee, United States, 37920 | |
| Meharry Medical College | |
| Nashville, Tennessee, United States, 37208 | |
| United States, Texas | |
| Lyndon Baines Johnson General Hospital | |
| Houston, Texas, United States, 77026-1967 | |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | |
| Houston, Texas, United States, 77030 | |
| Ben Taub General Hospital | |
| Houston, Texas, United States, 77030 | |
| M D Anderson Cancer Center | |
| Houston, Texas, United States, 77030 | |
| Michael E DeBakey VA Medical Center | |
| Houston, Texas, United States, 77030 | |
| MD Anderson Regional Care Center-Katy | |
| Houston, Texas, United States, 77094 | |
| MD Anderson Regional Care Center-Bay Area | |
| Nassau Bay, Texas, United States, 77058 | |
| MD Anderson Regional Care Center-Sugar Land | |
| Sugar Land, Texas, United States, 77478 | |
| MD Anderson Regional Care Center-The Woodlands | |
| The Woodlands, Texas, United States, 77384 | |
| United States, Utah | |
| Huntsman Cancer Institute/University of Utah | |
| Salt Lake City, Utah, United States, 84112 | |
| United States, Virginia | |
| Inova Fairfax Hospital | |
| Falls Church, Virginia, United States, 22042 | |
| Lynchburg Hematology-Oncology Clinic | |
| Lynchburg, Virginia, United States, 24501 | |
| Memorial Hospital Of Martinsville | |
| Martinsville, Virginia, United States, 24115 | |
| Virginia Commonwealth University/Massey Cancer Center | |
| Richmond, Virginia, United States, 23298 | |
| VCU Community Memorial Health Center | |
| South Hill, Virginia, United States, 23970 | |
| Shenandoah Oncology Associates PC | |
| Winchester, Virginia, United States, 22601 | |
| United States, Washington | |
| MultiCare Auburn Medical Center | |
| Auburn, Washington, United States, 98001 | |
| PeaceHealth Saint Joseph Medical Center | |
| Bellingham, Washington, United States, 98225 | |
| Highline Medical Center-Main Campus | |
| Burien, Washington, United States, 98166 | |
| Providence Regional Cancer Partnership | |
| Everett, Washington, United States, 98201 | |
| MultiCare Gig Harbor Medical Park | |
| Gig Harbor, Washington, United States, 98335 | |
| Kadlec Clinic Hematology and Oncology | |
| Kennewick, Washington, United States, 99336 | |
| Seattle Cancer Care Alliance at EvergreenHealth | |
| Kirkland, Washington, United States, 98034 | |
| Skagit Valley Hospital | |
| Mount Vernon, Washington, United States, 98274 | |
| Jefferson Healthcare | |
| Port Townsend, Washington, United States, 98368 | |
| MultiCare Good Samaritan Hospital | |
| Puyallup, Washington, United States, 98372 | |
| Minor and James Medical PLLC | |
| Seattle, Washington, United States, 98104 | |
| Fred Hutchinson Cancer Research Center | |
| Seattle, Washington, United States, 98109 | |
| Group Health Cooperative-Seattle | |
| Seattle, Washington, United States, 98112 | |
| Swedish Medical Center-First Hill | |
| Seattle, Washington, United States, 98122-4307 | |
| University of Washington Medical Center | |
| Seattle, Washington, United States, 98195 | |
| Rockwood Clinic Cancer Treatment Center-Valley | |
| Spokane Valley, Washington, United States, 99216 | |
| Rockwood Cancer Treatment Center-DHEC-Downtown | |
| Spokane, Washington, United States, 99204 | |
| Rockwood Clinic | |
| Spokane, Washington, United States, 99220 | |
| MultiCare Tacoma General Hospital | |
| Tacoma, Washington, United States, 98405 | |
| Northwest NCI Community Oncology Research Program | |
| Tacoma, Washington, United States, 98405 | |
| Madigan Army Medical Center | |
| Tacoma, Washington, United States, 98431 | |
| Legacy Salmon Creek Hospital | |
| Vancouver, Washington, United States, 98686 | |
| Providence Saint Mary Regional Cancer Center | |
| Walla Walla, Washington, United States, 99362 | |
| United States, West Virginia | |
| West Virginia University Charleston | |
| Charleston, West Virginia, United States, 25304 | |
| Edwards Comprehensive Cancer Center | |
| Huntington, West Virginia, United States, 25701 | |
| United States, Wisconsin | |
| Langlade Hospital and Cancer Center | |
| Antigo, Wisconsin, United States, 54409 | |
| Aurora Cancer Care-Southern Lakes VLCC | |
| Burlington, Wisconsin, United States, 53105 | |
| Marshfield Clinic-Chippewa Center | |
| Chippewa Falls, Wisconsin, United States, 54729 | |
| Marshfield Clinic Cancer Center at Sacred Heart | |
| Eau Claire, Wisconsin, United States, 54701 | |
| Sacred Heart Hospital | |
| Eau Claire, Wisconsin, United States, 54701 | |
| Aurora Health Center-Fond du Lac | |
| Fond du Lac, Wisconsin, United States, 54937 | |
| Aurora Health Care Germantown Health Center | |
| Germantown, Wisconsin, United States, 53022 | |
| Aurora Cancer Care-Grafton | |
| Grafton, Wisconsin, United States, 53024 | |
| Green Bay Oncology at Saint Vincent Hospital | |
| Green Bay, Wisconsin, United States, 54301-3526 | |
| Saint Vincent Hospital Cancer Center Green Bay | |
| Green Bay, Wisconsin, United States, 54301 | |
| Green Bay Oncology Limited at Saint Mary's Hospital | |
| Green Bay, Wisconsin, United States, 54303 | |
| Saint Vincent Hospital Cancer Center at Saint Mary's | |
| Green Bay, Wisconsin, United States, 54303 | |
| Aurora BayCare Medical Center | |
| Green Bay, Wisconsin, United States, 54311 | |
| UW Cancer Center Johnson Creek | |
| Johnson Creek, Wisconsin, United States, 53038 | |
| Aurora Cancer Care-Kenosha South | |
| Kenosha, Wisconsin, United States, 53142 | |
| Gundersen Lutheran Medical Center | |
| La Crosse, Wisconsin, United States, 54601 | |
| Marshfield Clinic - Ladysmith Center | |
| Ladysmith, Wisconsin, United States, 54848 | |
| University of Wisconsin Hospital and Clinics | |
| Madison, Wisconsin, United States, 53792 | |
| Holy Family Memorial Hospital | |
| Manitowoc, Wisconsin, United States, 54221 | |
| Aurora Bay Area Medical Group-Marinette | |
| Marinette, Wisconsin, United States, 54143 | |
| Vince Lombardi Cancer Clinic-Marinette | |
| Marinette, Wisconsin, United States, 54143 | |
| Marshfield Clinic | |
| Marshfield, Wisconsin, United States, 54449 | |
| Saint Joseph's Hospital | |
| Marshfield, Wisconsin, United States, 54449 | |
| Aurora Cancer Care-Milwaukee | |
| Milwaukee, Wisconsin, United States, 53209 | |
| Aurora Saint Luke's Medical Center | |
| Milwaukee, Wisconsin, United States, 53215 | |
| Froedtert and the Medical College of Wisconsin | |
| Milwaukee, Wisconsin, United States, 53226 | |
| Aurora Sinai Medical Center | |
| Milwaukee, Wisconsin, United States, 53233 | |
| Marshfield Clinic-Minocqua Center | |
| Minocqua, Wisconsin, United States, 54548 | |
| Cancer Center of Western Wisconsin | |
| New Richmond, Wisconsin, United States, 54017 | |
| Green Bay Oncology - Oconto Falls | |
| Oconto Falls, Wisconsin, United States, 54154 | |
| Vince Lombardi Cancer Clinic - Oshkosh | |
| Oshkosh, Wisconsin, United States, 54904 | |
| Aurora Cancer Care-Racine | |
| Racine, Wisconsin, United States, 53406 | |
| Marshfield Clinic at James Beck Cancer Center | |
| Rhinelander, Wisconsin, United States, 54501 | |
| Saint Mary's Hospital | |
| Rhinelander, Wisconsin, United States, 54501 | |
| Marshfield Clinic-Rice Lake Center | |
| Rice Lake, Wisconsin, United States, 54868 | |
| HSHS Saint Nicholas Hospital | |
| Sheboygan, Wisconsin, United States, 53081 | |
| Vince Lombardi Cancer Clinic-Sheboygan | |
| Sheboygan, Wisconsin, United States, 53081 | |
| Marshfield Clinic Cancer Care at Saint Michael's Hospital | |
| Stevens Point, Wisconsin, United States, 54481 | |
| Saint Michael's Hospital | |
| Stevens Point, Wisconsin, United States, 54481 | |
| Marshfield Clinic Stevens Point Center | |
| Stevens Point, Wisconsin, United States, 54482 | |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | |
| Sturgeon Bay, Wisconsin, United States, 54235-1495 | |
| Green Bay Oncology - Sturgeon Bay | |
| Sturgeon Bay, Wisconsin, United States, 54235 | |
| Aurora Medical Center in Summit | |
| Summit, Wisconsin, United States, 53066 | |
| Vince Lombardi Cancer Clinic-Two Rivers | |
| Two Rivers, Wisconsin, United States, 54241 | |
| Aurora Cancer Care-Waukesha | |
| Waukesha, Wisconsin, United States, 53188 | |
| Aspirus Regional Cancer Center | |
| Wausau, Wisconsin, United States, 54401 | |
| Marshfield Clinic-Wausau Center | |
| Wausau, Wisconsin, United States, 54401 | |
| Aurora Cancer Care-Milwaukee West | |
| Wauwatosa, Wisconsin, United States, 53226 | |
| Aurora West Allis Medical Center | |
| West Allis, Wisconsin, United States, 53227 | |
| Diagnostic and Treatment Center | |
| Weston, Wisconsin, United States, 54476 | |
| Marshfield Clinic - Weston Center | |
| Weston, Wisconsin, United States, 54476 | |
| Aspirus UW Cancer Center | |
| Wisconsin Rapids, Wisconsin, United States, 54494 | |
| Marshfield Clinic - Wisconsin Rapids Center | |
| Wisconsin Rapids, Wisconsin, United States, 54494 | |
| United States, Wyoming | |
| Billings Clinic-Cody | |
| Cody, Wyoming, United States, 82414 | |
Sponsors and Collaborators
Southwest Oncology Group
Millennium Pharmaceuticals, Inc.
National Cancer Institute (NCI)
Investigators
| Principal Investigator: | Neeraj Agarwal, M.D. | University of Utah |
| Responsible Party: | Southwest Oncology Group |
| ClinicalTrials.gov Identifier: | NCT01809691 History of Changes |
| Other Study ID Numbers: |
S1216 SWOG-S1216 ( Other Grant/Funding Number: U10CA180888 ) NCI-2012-02876 ( Other Identifier: NCI ) |
| First Posted: | March 13, 2013 Key Record Dates |
| Last Update Posted: | August 17, 2017 |
| Last Verified: | August 2017 |
| Individual Participant Data (IPD) Sharing Statement: | |
| Plan to Share IPD: | Yes |
| Plan Description: | https://swog.org/Visitors/Download/Policies/Policy43.pdf |
| Studies a U.S. FDA-regulated Drug Product: | Yes | |
| Studies a U.S. FDA-regulated Device Product: | No | |
Keywords provided by Southwest Oncology Group:
|
Prostate cancer TAK-700 Bicalutamide |
S1216 androgen therapy Phase III |
Additional relevant MeSH terms:
|
Prostatic Neoplasms Genital Neoplasms, Male Urogenital Neoplasms Neoplasms by Site Neoplasms Genital Diseases, Male Prostatic Diseases Androgens |
Bicalutamide Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Physiological Effects of Drugs Androgen Antagonists Hormone Antagonists Antineoplastic Agents |