ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01590862|
Recruitment Status : Recruiting
First Posted : May 3, 2012
Last Update Posted : March 6, 2019
|Condition or disease|
|Obsessive Compulsive Disorder Major Depressive Disorder|
|Study Type :||Observational|
|Estimated Enrollment :||60 participants|
|Official Title:||ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators|
|Study Start Date :||June 2012|
|Estimated Primary Completion Date :||December 2020|
|Estimated Study Completion Date :||December 2020|
Deep Brain Stimulation Effects on Reward Motivation
We will assess changes in Reward Motivation behavior with Deep Brain Stimulation on and off.
Patients with MDD or OCD
Patients with MDD or OCD who do not have a deep brain stimulator.
- Effort Expenditure for Rewards Task (EEfRT) [ Time Frame: 2 hours ]The EEfRT is a multi-trial computer-based task that assess an individual's willingness to expend effort for the chance to earn monetary rewards. We will assess whether stimulation of the Ventral Capsule/Ventral Striatum has an effect on behavior by executing this task with the DBS system on and off.
- Reward learning (clock task) [ Time Frame: 2 hours ]This task is an additional reward task that assesses reward learning. We will assess whether stimulation of the Ventral Capsule/Ventral Striatum has an effect on behavior by executing this task with the DBS system on and off.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01590862
|Contact: Aishwarya Gosai, BAfirstname.lastname@example.org|
|United States, Massachusetts|
|Massachusetts General Hospital||Recruiting|
|Boston, Massachusetts, United States, 02114|
|Contact: Darin D Dougherty, MD email@example.com|
|Principal Investigator: Darin D Dougherty, MD|
|Massachusetts General Hospital||Not yet recruiting|
|Charlestown, Massachusetts, United States, 02129|
|Contact: Anna L Gilmour, BA 617-726-9281 firstname.lastname@example.org|
|Principal Investigator: Darin D Daugherty, MD|