Exercise in Breast Cancer Survivors
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01582685|
Recruitment Status : Withdrawn (no patients enrolled)
First Posted : April 23, 2012
Last Update Posted : December 2, 2014
|Condition or disease||Intervention/treatment||Phase|
|Breast Cancer Obesity||Behavioral: Exercise||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||0 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Exercise in Breast Cancer Survivors: Analysis of Angiogenic Profile|
|Study Start Date :||April 2012|
|Actual Primary Completion Date :||June 2014|
|Actual Study Completion Date :||June 2014|
Experimental: Exercise Group
The intervention is a structured walking program which will be performed partly in the Pavilion Physical Therapy clinic and partly at home. The participant will be instructed in how hard to exercise, how long to exercise, and how many times in a week to exercise. You will also be instructed in how to exercise safely.
The participant will exercise for 16 weeks under supervision. The exercise regimen is increased slowly over 16 weeks.
No Intervention: No Exercise
These participants will receive standard of care follow up.
- Number of participants that complete the study as a measure of feasibility of an exercise intervention in obese breast cancer survivors. [ Time Frame: 12 months ]Number of participants that enroll in the study and actually complete the study
- IGF-1, endostatin, and VEGF levels in obese breast cancer survivors undergoing an exercise intervention as a measure of angiostatic phenotype: [ Time Frame: 12 months ]IFG-1 levels,unbound VEGF levels, Endostatin levels
- Amount of adipose tissue mass as measured on CT scans in obese breast cancer survivors before and after exercise intervention as a measure of weight loss [ Time Frame: 12 months ]Adipose tissue mass volume as measured on CT scan
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01582685
|United States, Mississippi|
|University of Mississippi Health Care|
|Jackson, Mississippi, United States, 39216|
|Principal Investigator:||Natale Sheehan, MD||University of Mississippi Health Care|