Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2016 by Alliance for Clinical Trials in Oncology
Sponsor:
Collaborator:
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Alliance for Clinical Trials in Oncology
ClinicalTrials.gov Identifier:
NCT01556243
First received: March 15, 2012
Last updated: June 17, 2016
Last verified: June 2016
  Purpose

RATIONALE: Breast-conserving surgery is a less invasive type of surgery for breast cancer and may have fewer side effects and improve recovery. Radiation therapy uses high-energy x rays to kill tumor cells. Giving radiation therapy after surgery may kill any tumor cells that remain after surgery.

PURPOSE: This phase II trial studies how well breast-conserving surgery and radiation therapy work in treating patients with multiple ipsilateral breast cancer


Condition Intervention Phase
Breast Cancer
Procedure: therapeutic conventional surgery
Radiation: whole breast irradiation
Phase 2

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Impact of Breast Conservation Surgery on Surgical Outcomes and Cosmesis in Patients With Multiple Ipsilateral Breast Cancers (MIBC)

Resource links provided by NLM:


Further study details as provided by Alliance for Clinical Trials in Oncology:

Primary Outcome Measures:
  • Local recurrence defined as histologic evidence of ductal carcinoma in situ or invasive breast cancer in the ipsilateral breast or chest wall assessed up to 5 years [ Time Frame: Up to 5 years post-treatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Conversion rate to mastectomy secondary to persistent positive margins assessed [ Time Frame: Up to 5 years post-treatment ] [ Designated as safety issue: No ]
  • Type and severity of adverse effects of breast-conserving surgery and radiation as assessed by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 [ Time Frame: Up to 30 days post-treatment ] [ Designated as safety issue: Yes ]
  • Radiation-related side effects of whole-breast radiation with a boost to 1 large or > 1 lumpectomy site as assessed by NCI CTCAE version 4.0 [ Time Frame: Up to 30 days post-treatment ] [ Designated as safety issue: Yes ]
  • Patient's perception of cosmesis assessed up to 24 months after WBI using the BREAST-Q© scoring module [ Time Frame: Up to 2 years post-treatment ] [ Designated as safety issue: No ]

Estimated Enrollment: 230
Study Start Date: July 2012
Estimated Primary Completion Date: July 2020 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Breast conservation surgery and radiation therapy
Patients undergo breast conserving surgery. Patients receive adjuvant chemotherapy at the physician's discretion. Patients receiving chemotherapy will start treatment within 12 weeks following surgery. Patients receive radiation therapy within 8 weeks following the last dose of chemotherapy or within 10 weeks following surgery if not receiving chemotherapy. Patients receive endocrine therapy at the physician's discretion. Patient observation will occur every 6 months until 5 years after the end of radiation therapy.
Procedure: therapeutic conventional surgery Radiation: whole breast irradiation

Detailed Description:

OBJECTIVES:

Primary

  • To assess the local recurrence (LR) rate with breast-conservation in patients with multiple ipsilateral primary breast cancer (MIBC).

Secondary

  • To examine the conversion rate to mastectomy secondary to persistent positive margins; poor cosmesis within the first year of attempting breast-conservation surgery (BCS) or inability to satisfy the radiation dose constraints on the boost to the lumpectomy bed of each site of disease.
  • To assess whether patients who did not undergo re-excision for close margins (< 2 mm) have a higher local recurrence (LR) rate than patients for whom negative margins were achieved.
  • To assess patient's perception of cosmesis and incidence of breast lymphedema.
  • To assess incidence of breast lymphedema
  • To examine the type and severity of adverse effects of breast conserving surgery and radiation for women with multiple ipsilateral primary breast cancer (MIBC).
  • To examine the radiation-related side effects of whole-breast radiation with a boost to 1 large or > 1 lumpectomy site.

OUTLINE: This is a multicenter study.

Patients undergo breast-conserving surgery (BCS) with all lesions resected to negative margins using 1 lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon. Patients receive adjuvant chemotherapy and/or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.

  Eligibility

Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Registration Inclusion Criteria:

  1. Age ≥ 40 years per National Comprehensive Cancer Network (NCCN) recommendations for breast conservation.
  2. Life Expectancy of at least 5 years, excluding diagnosis of breast cancer (Comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration)
  3. Female Gender - Men are excluded from this study. Male breast cancer is a rare event.

    Men are rarely candidates for breast conservation surgery due to small breast size. Men are less likely to be candidates for breast conservation surgery if found to have MIBC.

    Men are rarely candidates for breast conservation surgery due to small breast size. Men are less likely to be candidates for breast conservation surgery if found to have MIBC.

  4. Foci of Breast Cancer

    4.1 Upon clinical exam and pre-operative imaging by mammogram +/- MRI, two or three foci of biopsy proven breast cancer separated by > 2 cm of normal breast tissue.

    4.2 Foci must include at least one focus of invasive breast carcinoma with another focus of either invasive breast carcinoma or ductal carcinoma in situ (DCIS).

    No more than 2 quadrants with biopsy proven breast cancer.

    4.3 Note: The shortest distance between lesions must be reported on mammogram +/- MRI and eligibility criteria must be met on both, if both are obtained.

    4.4 Note: Patient is eligible for study if lesion is not visualized on all imaging modalities (i.e., any of the lesion(s) is/are visualized on MRI but not on mammogram OR visualized on mammogram but not on MRI).

    4.5 Ultrasound cannot be used to determine patient eligibility; eligibility to be determined by bilateral mammogram +/- MRI only.

    4.6 Fine needle aspirate of the second or third lesion to document malignancy is allowed if the first focus is shown to be invasive by core needle biopsy.

    4.7 Patient may remain on study if, upon pathological assessment, two or three lesions identified on pre-operative imaging represent one contiguous lesion.

  5. Patients may be registered AFTER surgery and PRIOR TO radiation therapy if either of the criteria is met:

    5.1 An area of atypia > 2cm from the index lesion excised at the time of cancer operation is upgraded to DCIS or invasive carcinoma thereby identifying MIBC. OR

    5.2 Patient underwent resection of two or three foci of malignancy by breast conservation surgery with a minimum of one invasive focus of breast cancer and a minimum of 2 cm of normal breast tissue between the lesions on final pathology.

  6. Mammogram Imaging - Bilateral mammogram ≤ 90 days prior to date of surgery.

    6.1 Note: For patients undergoing more than 1 breast operation, this is the date of the first breast surgery for breast cancer treatment.

  7. Staging of Cancer - cN0 or cN1 disease
  8. ECOG Performance Status (PS) - 0, 1, or 2.
  9. Ability to Complete Questionnaires - Ability to complete questionnaire(s) by themselves or with assistance
  10. Ability to Provide Written Informed Consent
  11. Willing to Return to Enrolling Institution - Willing to return to enrolling institution for follow-up during the Active Monitoring Phase (the active treatment and observation portions) of the study. Patients are encouraged to return to the enrolling institution; however, patients may receive radiation therapy at a different institution other than the enrolling institution.

Registration Exclusion Criteria:

  1. Pregnancy, Nursing and Requirement for Contraception - Pregnant women, nursing women and women of childbearing potential who are unwilling to employ adequate contraception (as determined by the treating physician) are excluded from participation.

    This study involves radiation therapy (WBI) that has known genotoxic, mutagenic and teratogenic effects.

  2. Size of Single Focus of Disease on Preoperative Imaging - Largest single focus of disease > 5 centimeters by either mammogram or MRI or both. Note: Measurement of the largest single focus should include any satellite lesions within 1 centimeter of the index lesion.
  3. Prior Staging Procedure - Surgical axillary staging procedure prior to first definitive breast operation. Note: FNA or core needle biopsy of axillary node is permitted.
  4. Evidence of Metastatic Disease - Clinical or radiographic evidence of metastatic disease
  5. Prior History of Breast Cancer - Prior history of ipsilateral breast cancer [DCIS, LCIS (lobular cancer in situ) or invasive]
  6. Staging of Cancer - cNX, cN2, or cN3 disease
  7. Breast Implants - Breast implants at time of diagnosis. Note: Patients who have had implants previously removed prior to diagnosis are eligible.
  8. Systemic Illnesses or Concurrent Disease - Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole breast irradiation (such as connective tissue disorders, lupus, scleroderma).
  9. Uncontrolled Intercurrent Illness - Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
  10. Bilateral Breast Cancer - Prior or current LCIS, DCIS or invasive breast cancer in the opposite breast (i.e., bilateral disease is not allowed).
  11. Disallowed Prior Treatments - Treatment including radiation therapy, chemotherapy, biotherapy, hormonal therapy for this cancer prior to surgery (i.e., any neoadjuvant chemotherapy or endocrine therapy is not allowed). Patients who undergo surgical resection with breast conservation and then are treated with adjuvant systemic therapy are eligible to enroll prior to the start of radiotherapy.
  12. Partial Breast Radiation - Planned partial breast radiation.
  13. Known BRCA Mutations - Patients with known BRCA mutations. Patients who are not tested or whose testing result is not returned at the time of registration are not excluded from registering to this study.
  14. Other Active Malignancies - Other active malignancy ≤ 5 years prior to registration.

14.1 Exceptions: Non-melanotic skin cancer or carcinoma-in-situ of the cervix.

14.2 Note: If there is a history of prior malignancy, they must not be receiving other specific treatment for their cancer.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01556243

Contacts
Contact: Judy Boughey, MD (507) 284-3629

  Hide Study Locations
Locations
United States, Arkansas
CHI Saint Vincent Cancer Center Hot Springs Recruiting
Hot Springs, Arkansas, United States, 71913
Contact: Mehmet Copur, MD    308-398-5450      
United States, California
Epic Care-Dublin Recruiting
Dublin, California, United States, 94568
Contact: James Feusner, MD    510-428-3689      
Bay Area Breast Surgeons, Incorporated Recruiting
Emeryville, California, United States, 94608
Contact: James Feusner, MD    510-428-3689      
Epic Care Partners in Cancer Care Recruiting
Emeryville, California, United States, 94608
Contact: James Feusner, MD    510-428-3689      
UC San Diego Moores Cancer Center Recruiting
La Jolla, California, United States, 92093
Contact: Sarah Blair, MD    858-822-5354      
Cedars Sinai Medical Center Recruiting
Los Angeles, California, United States, 90048
Contact: Armando Giuliano, MD    310-423-9331      
Cedars-Sinai Medical Center Recruiting
Los Angeles, California, United States, 90048
Contact: Armando Giuliano, MD    310-423-9331      
Contra Costa Regional Medical Center Recruiting
Martinez, California, United States, 94553
Contact: James Feusner, MD    510-428-3689      
Alta Bates Summit Medical Center-Summit Campus Recruiting
Oakland, California, United States, 94609
Contact: James Feusner, MD    510-428-3689      
Bay Area Tumor Institute Recruiting
Oakland, California, United States, 94609
Contact: James Feusner, MD    510-428-3689      
Stanford Cancer Institute Recruiting
Palo Alto, California, United States, 94304
Contact: Frederick Dirbas, MD    650-723-6779      
Naval Medical Center-San Diego Recruiting
San Diego, California, United States, 92134-3202
Contact: Preston Gable, MD    619-532-7303      
United States, Colorado
University of Colorado Cancer Center-Anschutz Cancer Pavilion Recruiting
Aurora, Colorado, United States, 80045
Contact: Nicole Kounalakis, MD    720-848-0650      
Catholic Health Initiatives NCORP Recruiting
Englewood, Colorado, United States, 80112
Contact: Mehmet Copur, MD    308-398-5450      
United States, Connecticut
Smilow Cancer Hospital Care Center at Saint Francis Recruiting
Hartford, Connecticut, United States, 06105
Contact: Philip Stella, MD    734-712-4931      
United States, Delaware
Beebe Medical Center Recruiting
Lewes, Delaware, United States, 19958
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Christiana Care Health System-Christiana Hospital Recruiting
Newark, Delaware, United States, 19718
Contact: Diana Witmer-Dickson, MD    302-623-4343      
Delaware Clinical and Laboratory Physicians PA Recruiting
Newark, Delaware, United States, 19713
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Helen F. Graham Cancer Center Recruiting
Newark, Delaware, United States, 19713
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Medical Oncology Hematology Consultants PA Recruiting
Newark, Delaware, United States, 19713
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Regional Hematology and Oncology PA Recruiting
Newark, Delaware, United States, 19713
Contact: Diana Witmer-Dickson, MD    302-623-4343      
Christiana Gynecologic Oncology LLC Recruiting
Newark, Delaware, United States, 19713
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Beebe Health Campus Recruiting
Rehoboth Beach, Delaware, United States, 19971
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Nanticoke Memorial Hospital Recruiting
Seaford, Delaware, United States, 19973
Contact: Diana Dickson-Witmer, MD    302-623-4343      
Christiana Care Health System-Wilmington Hospital Recruiting
Wilmington, Delaware, United States, 19801
Contact: Diana Dickson-Witmer, MD    302-623-4343      
United States, Florida
Morton Plant Hospital Recruiting
Clearwater, Florida, United States, 33756
Contact: Peter Blumencranz, MD    727-462-2131      
University of Miami Miller School of Medicine-Sylvester Cancer Center Recruiting
Miami, Florida, United States, 33136
Contact: Eli Avisar, MD    305-243-3379      
Mount Sinai Medical Center Recruiting
Miami Beach, Florida, United States, 33140
Contact: Michael Schwartz, MD    305-674-2625      
United States, Georgia
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Recruiting
Savannah, Georgia, United States, 31405
Contact: Howard Zaren, MD    912-819-5704      
United States, Hawaii
Oncare Hawaii, Incorporated-Pali Momi Recruiting
Aiea, Hawaii, United States, 96701
Contact: Jeffrey Berenberg, MD    808-433-4089      
Pali Momi Medical Center Recruiting
Aiea, Hawaii, United States, 96701
Contact: Jeffrey Berenberg, MD    808-433-4089      
The Cancer Center of Hawaii-Leeward Recruiting
Ewa Beach, Hawaii, United States, 96706
Contact: Jeffrey Berenberg, MD    808-433-4089      
Oncare Hawaii Inc-POB II Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey Berenberg, MD    808-586-2979      
Queen's Medical Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey Berenberg, MD    808-433-4089      
Kapiolani Medical Center for Women and Children Recruiting
Honolulu, Hawaii, United States, 96826
Contact: Jeffrey Berenberg, MD    808-433-4089      
University of Hawaii Cancer Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey Berenberg, MD    808-433-4089      
Kuakini Medical Center Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey Berenberg, MD    808-586-2979      
OnCare Hawaii, Incorporated-Kuakini Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey Berenberg, MD    808-433-4089      
OnCare Hawaii-Liliha Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey Berenberg, MD    808-524-6115      
The Cancer Center of Hawaii-Liliha Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey Berenberg, MD    808-433-4089      
Straub Clinic and Hospital Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey Berenberg, MD    808-433-4089      
Wilcox Memorial Hospital and Kauai Medical Clinic Recruiting
Lihue, Hawaii, United States, 96766
Contact: Jeffrey Berenberg, MD    808-433-4089      
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Recruiting
Boise, Idaho, United States, 83706
Contact: Philip Stella, MD    734-712-4931      
Kootenai Medical Center Recruiting
Couer D'Alene, Idaho, United States, 83814
Contact: Benjamin Marchello, MD    406-237-5460      
Kootenai Cancer Center Recruiting
Post Falls, Idaho, United States, 83854
Contact: Benjamin Marchello, MD    406-237-5460      
Kootenai Cancer Clinic Recruiting
Sandpoint, Idaho, United States, 83864
Contact: Benjamin Marchello, MD    406-237-5460      
United States, Illinois
Saint Joseph Medical Center Recruiting
Bloomington, Illinois, United States, 61701
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Bloomington Recruiting
Bloomington, Illinois, United States, 61704
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Canton Recruiting
Canton, Illinois, United States, 61520
Contact: James Wade, MD    217-876-6600      
Memorial Hospital of Carbondale Recruiting
Carbondale, Illinois, United States, 62902
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Carthage Recruiting
Carthage, Illinois, United States, 62321
Contact: James Wade, MD    217-876-6600      
Centralia Oncology Clinic Recruiting
Centralia, Illinois, United States, 62801
Contact: James Wade, MD    217-876-6600      
University of Illinois Recruiting
Chicago, Illinois, United States, 60612
Contact: Alejandra Perez-Tamayo, MD    954-210-1168      
Cancer Care Specialists of Central Illinois Recruiting
Decatur, Illinois, United States, 62526
Contact: James Wade, MD    217-876-6600      
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: James Wade, MD    217-876-6600      
Crossroads Cancer Center Recruiting
Effingham, Illinois, United States, 62401
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Eureka Recruiting
Eureka, Illinois, United States, 61530
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Galesburg Recruiting
Galesburg, Illinois, United States, 61401
Contact: James Wade, MD    217-876-6600      
Western Illinois Cancer Treatment Center Recruiting
Galesburg, Illinois, United States, 61401
Contact: James Wade, MD    217-876-6600      
Ingalls Memorial Hospital Recruiting
Harvey, Illinois, United States, 60426
Contact: Mark Kozloff, MD    708-339-4800      
Illinois CancerCare-Kewanee Clinic Recruiting
Kewanee, Illinois, United States, 61443
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Macomb Recruiting
Macomb, Illinois, United States, 61455
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Ottawa Clinic Recruiting
Ottawa, Illinois, United States, 61350
Contact: James Wade, MD    217-876-6600      
Radiation Oncology of Northern Illinois Recruiting
Ottawa, Illinois, United States, 61350
Contact: James Wade, MD    217-876-6600      
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Recruiting
Pekin, Illinois, United States, 61554
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Pekin Recruiting
Pekin, Illinois, United States, 61603
Contact: James Wade, MD    217-876-6600      
Methodist Medical Center of Illinois Recruiting
Peoria, Illinois, United States, 61603
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: James Wade, MD    217-876-6600      
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Recruiting
Peoria, Illinois, United States, 61615
Contact: James Wade, MD    217-876-6600      
OSF Saint Francis Medical Center Recruiting
Peoria, Illinois, United States, 61637
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Peru Recruiting
Peru, Illinois, United States, 61354
Contact: James Wade, MD    217-876-6600      
Valley Radiation Oncology Recruiting
Peru, Illinois, United States, 61354
Contact: James Wade, MD    217-876-6600      
Illinois CancerCare-Princeton Recruiting
Princeton, Illinois, United States, 61356
Contact: James Wade, MD    217-876-6600      
Central Illinois Hematology Oncology Center Recruiting
Springfield, Illinois, United States, 62702
Contact: James Wade, MD    217-876-6600      
Southern Illinois University School of Medicine Recruiting
Springfield, Illinois, United States, 62702
Contact: James Wade, MD    217-876-6600      
Springfield Clinic Recruiting
Springfield, Illinois, United States, 62703
Contact: James Wade, MD    217-876-6600      
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781
Contact: James Wade, MD    217-876-6600      
Cancer Care Specialists of Illinois-Swansea Recruiting
Swansea, Illinois, United States, 62226
Contact: James Wade, MD    217-876-6600      
United States, Indiana
IU Health West Hospital Recruiting
Avon, Indiana, United States, 46123
Contact: Linda Han, MD    317-274-3616      
IU Health North Hospital Recruiting
Carmel, Indiana, United States, 46032
Contact: Linda Han, MD    317-274-3616      
IU Health Central Indiana Cancer Centers-Fishers Recruiting
Fishers, Indiana, United States, 46037
Contact: Linda Han, MD    317-274-3616      
Indiana University-Melvin and Bren Simon Cancer Center Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Linda Han, MD    317-274-3616      
IU Health Methodist Hospital Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Linda Han, MD    317-274-2552      
Sidney and Lois Eskenazi Hospital Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Linda Han, MD    317-274-2552      
Memorial Regional Cancer Center-Day Road Recruiting
Mishawaka, Indiana, United States, 46544
Contact: Thomas Reid, MD    574-647-1100      
Saint Joseph Regional Medical Center-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545
Contact: Robin Zon, MD    574-296-6536      
Memorial Hospital of South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Thomas Reid, MD    574-647-1100      
Michiana Hematology Oncology PC-South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Robin Zon, MD    574-296-6536      
United States, Iowa
Mary Greeley Medical Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph Merchant, MD    515-956-2759      
McFarland Clinic PC-William R Bliss Cancer Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph Merchant, MD    515-956-2759      
McFarland Clinic PC-Boone Recruiting
Boone, Iowa, United States, 50036
Contact: Joseph Merchant, MD    515-956-2759      
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet Copur, MD    308-398-5450      
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet Copur, MD    308-398-5450      
Alegent Health Mercy Hospital Recruiting
Council Bluffs, Iowa, United States, 51503
Contact: Mehmet Copur, MD    308-398-5450      
Greater Regional Medical Center Recruiting
Creston, Iowa, United States, 50801
Contact: Mehmet Copur, MD    308-398-5450      
Iowa Lutheran Hospital Recruiting
Des Moines, Iowa, United States, 50316
Contact: Robert Behrens, MD    515-241-3343      
Iowa-Wide Oncology Research Coalition NCORP Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert Behrens, MD    515-241-3343      
Medical Oncology and Hematology Associates-Des Moines Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert Behrens, MD    515-241-3343      
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert Behrens, MD    515-241-3343      
Mercy Medical Center-Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet Copur, MD    308-398-5450      
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet Copur, MD    308-398-5450      
McFarland Clinic PC-Trinity Cancer Center Recruiting
Fort Dodge, Iowa, United States, 50501
Contact: Joseph Merchant, MD    515-956-2759      
McFarland Clinic PC-Jefferson Recruiting
Jefferson, Iowa, United States, 50129
Contact: Joseph Merchant, MD    515-956-2759      
McFarland Clinic PC-Marshalltown Recruiting
Marshalltown, Iowa, United States, 50158
Contact: Joseph Merchant, MD    515-956-2759      
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Mehmet Copur, MD    308-398-5450      
Methodist West Hospital Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Robert Behrens, MD    515-241-3343      
United States, Kansas
Menorah Medical Center Recruiting
Overland Park, Kansas, United States, 66209
Contact: Rakesh Gaur, MD    913-948-5588      
Saint Luke's South Hospital Recruiting
Overland Park, Kansas, United States, 66213
Contact: Rakesh Gaur, MD    913-948-5588      
Kansas City NCI Community Oncology Research Program Recruiting
Prairie Village, Kansas, United States, 66208
Contact: Rakesh Gaur, MD    913-948-5588      
United States, Kentucky
Flaget Memorial Hospital Recruiting
Bardstown, Kentucky, United States, 40004
Contact: Mehmet Copur, MD    308-398-5450      
Commonwealth Cancer Center-Corbin Recruiting
Corbin, Kentucky, United States, 40701
Contact: Mehmet Copur, MD    308-398-5450      
Saint Elizabeth Medical Center South Recruiting
Edgewood, Kentucky, United States, 41017
Contact: Joseph Guenther, MD    859-301-9186      
Saint Elizabeth-Fort Thomas Recruiting
Fort Thomas, Kentucky, United States, 41075
Contact: Joseph Guenther, MD    859-301-9418      
Saint Joseph Radiation Oncology Resource Center Recruiting
Lexington, Kentucky, United States, 40504
Contact: Mehmet Copur, MD    308-398-5450      
Saint Joseph Hospital East Recruiting
Lexington, Kentucky, United States, 40509
Contact: Mehmet Copur, MD    308-398-5450      
Jewish Hospital Recruiting
Louisville, Kentucky, United States, 40202
Contact: Mehmet Copur, MD    308-398-5450      
The James Graham Brown Cancer Center at University of Louisville Recruiting
Louisville, Kentucky, United States, 40202
Contact: Nicolas Ajkay, MD    502-629-3355      
Jewish Hospital Medical Center Northeast Recruiting
Louisville, Kentucky, United States, 40245
Contact: Mehmet Copur, MD    308-398-5450      
Saints Mary and Elizabeth Hospital Recruiting
Louisville, Kentucky, United States, 40215
Contact: Mehmet Copur, MD    308-398-5450      
Jewish Hospital Medical Center South Recruiting
Shepherdsville, Kentucky, United States, 40165
Contact: Mehmet Copur, MD    308-398-5450      
United States, Maine
Eastern Maine Medical Center Recruiting
Bangor, Maine, United States, 04401
Contact: Thomas Openshaw, MD    207-973-7474      
Eastern Maine Medical Center Cancer Care Recruiting
Brewer, Maine, United States, 04412
Contact: Thomas Openshaw, MD    207-973-7474      
United States, Maryland
Sinai Hospital of Baltimore Recruiting
Baltimore, Maryland, United States, 21215
Contact: Mayer Gorbaty, MD    410-701-4466      
Saint Agnes Hospital Recruiting
Baltimore, Maryland, United States, 21229
Contact: Richard Hudes, MD    410-368-2965      
United States, Massachusetts
Dana-Farber Cancer Institute Recruiting
Boston, Massachusetts, United States, 02115
Contact: Katherina Calvillo, MD    781-624-4611      
Dana-Farber/Brigham and Women's Cancer Center at South Shore Recruiting
South Weymouth, Massachusetts, United States, 02190
Contact: Katherina Calvillo, MD    781-624-4611      
United States, Michigan
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Philip Stella, MD    734-712-4931      
Bronson Battle Creek Recruiting
Battle Creek, Michigan, United States, 49017
Contact: Gilbert Padula, MD    616-752-6218      
Oakwood Hospital and Medical Center Recruiting
Dearborn, Michigan, United States, 48124
Contact: Philip Stella, MD    734-712-4931      
Wayne State University/Karmanos Cancer Institute Recruiting
Detroit, Michigan, United States, 48201
Contact: Mary Kosir, MD    313-576-8490      
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Philip Stella, MD    734-712-4931      
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Philip Stella, MD    734-712-4931      
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48503
Contact: Philip Stella, MD    734-712-4931      
Mercy Health Saint Mary's Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Gilbert Padula, MD    616-752-6218      
Spectrum Health at Butterworth Campus Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Gilbert Padula, MD    616-752-6218      
Allegiance Health Recruiting
Jackson, Michigan, United States, 49201
Contact: Philip Stella, MD    734-712-4931      
Borgess Medical Center Recruiting
Kalamazoo, Michigan, United States, 49001
Contact: Gilbert Padula, MD    616-752-6218      
Bronson Methodist Hospital Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Gilbert Padula, MD    616-752-6218      
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Gilbert Padula, MD    616-752-6218      
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Philip Stella, MD    734-712-4931      
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Philip Stella, MD    734-712-4931      
Mercy Health Mercy Campus Recruiting
Muskegon, Michigan, United States, 49444
Contact: Gilbert Padula, MD    616-752-6218      
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341
Contact: Philip Stella, MD    734-712-4931      
William Beaumont Hospital-Royal Oak Recruiting
Royal Oak, Michigan, United States, 48073
Contact: Nayana Dekhne, MD    248-551-3300      
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Philip Stella, MD    734-712-4931      
Munson Medical Center Recruiting
Traverse City, Michigan, United States, 49684
Contact: Gilbert Padula, MD    616-752-6218      
William Beaumont Hospital-Troy Recruiting
Troy, Michigan, United States, 48098
Contact: Nayana Dekhne, MD    248-551-7695      
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Philip Stella, MD    734-712-4931      
United States, Minnesota
Fairview Ridges Hospital Recruiting
Burnsville, Minnesota, United States, 55337
Contact: Daniel Anderson, MD    952-993-1517      
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: Daniel Anderson, MD    952-993-1517      
Fairview-Southdale Hospital Recruiting
Edina, Minnesota, United States, 55435
Contact: Daniel Anderson, MD    952-993-1517      
Unity Hospital Recruiting
Fridley, Minnesota, United States, 55432
Contact: Daniel Anderson, MD    952-993-1517      
Minnesota Oncology Hematology PA-Maplewood Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Daniel Anderson, MD    952-993-1517      
Saint John's Hospital-Healtheast Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Daniel Anderson, MD    952-993-1517      
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: Daniel Anderson, MD    952-993-1517      
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: Daniel Anderson, MD    952-993-1517      
Health Partners Inc Recruiting
Minneapolis, Minnesota, United States, 55454
Contact: Daniel Anderson, MD    952-892-2000      
New Ulm Medical Center Recruiting
New Ulm, Minnesota, United States, 56073
Contact: Daniel Anderson, MD    952-993-1517      
North Memorial Medical Health Center Recruiting
Robbinsdale, Minnesota, United States, 55422
Contact: Daniel Anderson, MD    952-993-1517      
Mayo Clinic Cancer Center Recruiting
Rochester, Minnesota, United States, 55905
Contact: Judy Boughey, MD    507-284-3629      
Coborn Cancer Center at Saint Cloud Hospital Recruiting
Saint Cloud, Minnesota, United States, 56303
Contact: Donald Jurgens, MD    320-229-4907      
Saint Cloud Hospital Recruiting
Saint Cloud, Minnesota, United States, 56303
Contact: Donald Jurgens, MD    320-229-4907      
Metro Minnesota Community Oncology Research Consortium Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Daniel Anderson, MD    952-993-1517      
Park Nicollet Clinic-Saint Louis Park Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Daniel Anderson, MD    952-993-1517      
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: Daniel Anderson, MD    952-993-1517      
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: Daniel Anderson, MD    952-993-1517      
Saint Francis Regional Medical Center Recruiting
Shakopee, Minnesota, United States, 55379
Contact: Daniel Anderson, MD    952-993-1517      
Lakeview Hospital Recruiting
Stillwater, Minnesota, United States, 55082
Contact: Daniel Anderson, MD    952-993-1517      
Ridgeview Medical Center Recruiting
Waconia, Minnesota, United States, 55387
Contact: Daniel Anderson, MD    952-993-1517      
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: Daniel Anderson, MD    952-993-1517      
Minnesota Oncology and Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: Daniel Anderson, MD    952-993-1517      
United States, Missouri
Parkland Health Center-Bonne Terre Recruiting
Bonne Terre, Missouri, United States, 63628
Contact: James Wade, MD    217-876-6600      
Saint Francis Medical Center Recruiting
Cape Giradeau, Missouri, United States, 63703
Contact: James Wade, MD    217-876-6600      
Southeast Cancer Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James Wade, MD    217-876-6600      
Centerpoint Medical Center LLC Recruiting
Independence, Missouri, United States, 64057
Contact: Rakesh Gaur, MD    913-948-5588      
Capital Region Medical Center-Goldschmidt Cancer Center Recruiting
Jefferson City, Missouri, United States, 65109
Contact: James Wade, MD    217-876-6600      
Saint Luke's Hospital of Kansas City Recruiting
Kansas City, Missouri, United States, 64111
Contact: Rakesh Gaur, MD    913-948-5588      
Heartland Hematology and Oncology Associates Incorporated Recruiting
Kansas City, Missouri, United States, 64118
Contact: Rakesh Gaur, MD    913-948-5588      
Research Medical Center Recruiting
Kansas City, Missouri, United States, 64132
Contact: Rakesh Gaur, MD    913-948-5588      
Saint Luke's East-Lee's Summit Recruiting
Lee's Summit, Missouri, United States, 64086
Contact: Rakesh Gaur, MD    913-948-5588      
Liberty Radiation Oncology Center Recruiting
Liberty, Missouri, United States, 64068
Contact: Rakesh Gaur, MD    913-948-5588      
Washington University School of Medicine Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Julie Margenthaler, MD    314-362-7534      
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: James Wade, MD    217-876-6600      
Sainte Genevieve County Memorial Hospital Recruiting
Sainte Genevieve, Missouri, United States, 63670
Contact: James Wade, MD    217-876-6600      
Missouri Baptist Sullivan Hospital Recruiting
Sullivan, Missouri, United States, 63080
Contact: James Wade, MD    217-876-6600      
Missouri Baptist Outpatient Center-Sunset Hills Recruiting
Sunset Hills, Missouri, United States, 63127
Contact: James Wade, MD    217-876-6600      
United States, Montana
Montana Cancer Consortium NCORP Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin Marchello, MD    406-238-6290      
Saint Vincent Healthcare Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin Marchello, MD    406-238-6290      
Billings Clinic Cancer Center Recruiting
Billings, Montana, United States, 59107
Contact: Benjamin Marchello, MD    406-238-6290      
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Benjamin Marchello, MD    406-237-5460      
Saint James Community Hospital and Cancer Treatment Center Recruiting
Butte, Montana, United States, 59701
Contact: Benjamin Marchello, MD    406-238-6290      
Benefis Healthcare-Sletten Cancer Institute Recruiting
Great Falls, Montana, United States, 59405
Contact: Benjamin Marchello, MD    406-238-6290      
Saint Peter's Community Hospital Recruiting
Helena, Montana, United States, 59601
Contact: Benjamin Marchello, MD    406-238-6290      
Kalispell Regional Medical Center Recruiting
Kalispell, Montana, United States, 59901
Contact: Benjamin Marchello, MD    406-237-5460      
Saint Patrick Hospital-Community Hospital Recruiting
Missoula, Montana, United States, 59802
Contact: Benjamin Marchello, MD    406-238-6290      
Community Medical Hospital Recruiting
Missoula, Montana, United States, 59801
Contact: Benjamin Marchello, MD    406-237-5460      
United States, Nebraska
CHI Health Saint Francis Recruiting
Grand Island, Nebraska, United States, 68803
Contact: Mehmet Copur, MD    308-398-5450      
Heartland Hematology and Oncology Recruiting
Kearney, Nebraska, United States, 68845
Contact: Mehmet Copur, MD    308-398-5450      
CHI Health Good Samaritan Recruiting
Kearney, Nebraska, United States, 68847
Contact: Mehmet Copur, MD    308-398-5450      
Saint Elizabeth Regional Medical Center Recruiting
Lincoln, Nebraska, United States, 68510
Contact: Mehmet Copur, MD    308-398-5450      
Creighton University Medical Center Recruiting
Omaha, Nebraska, United States, 68131
Contact: Mehmet Copur, MD    308-398-5450      
Hematology and Oncology Consultants PC Recruiting
Omaha, Nebraska, United States, 68122
Contact: Mehmet Copur, MD    308-398-5450      
Alegent Health Bergan Mercy Medical Center Recruiting
Omaha, Nebraska, United States, 68124
Contact: Mehmet Copur, MD    308-398-5450      
Alegent Health Lakeside Hospital Recruiting
Omaha, Nebraska, United States, 68130
Contact: Mehmet Copur, MD    308-398-5450      
Alegent Health Immanuel Medical Center Recruiting
Omaha, Nebraska, United States, 68122
Contact: Mehmet Copur, MD    308-398-5450      
Midlands Community Hospital Recruiting
Papillion, Nebraska, United States, 68046
Contact: Mehmet Copur, MD    308-398-5450      
United States, Nevada
Comprehensive Cancer Centers of Nevada-Southeast Henderson Recruiting
Henderson, Nevada, United States, 89074
Contact: John Ellerton, MD    702-822-2000      
Cancer and Blood Specialists-Henderson Recruiting
Henderson, Nevada, United States, 89052
Contact: John Ellerton, MD    702-822-2000      
Las Vegas Cancer Center-Henderson Recruiting
Henderson, Nevada, United States, 89052
Contact: John Ellerton, MD    702-822-2000      
21st Century Oncology-Henderson Recruiting
Henderson, Nevada, United States, 89074
Contact: John Ellerton, MD    702-822-2000      
Comprehensive Cancer Centers of Nevada-Henderson Recruiting
Henderson, Nevada, United States, 89052
Contact: John Ellerton, MD    702-822-2000      
University Medical Center of Southern Nevada Recruiting
Las Vegas, Nevada, United States, 89102
Contact: John Ellerton, MD    702-384-0808      
Cancer and Blood Specialists-Shadow Recruiting
Las Vegas, Nevada, United States, 89106
Contact: John Ellerton, MD    702-822-2000      
Comprehensive Cancer Centers of Nevada-Central Valley Recruiting
Las Vegas, Nevada, United States, 89169
Contact: John Ellerton, MD    702-822-2000      
Radiation Oncology Centers of Nevada Central Recruiting
Las Vegas, Nevada, United States, 89106
Contact: John Ellerton, MD    702-822-2000      
21st Century Oncology-Fort Apache Recruiting
Las Vegas, Nevada, United States, 89109
Contact: John Ellerton, MD    702-822-2000      
21st Century Oncology Recruiting
Las Vegas, Nevada, United States, 89109
Contact: John Ellerton, MD    702-822-2000      
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Recruiting
Las Vegas, Nevada, United States, 89109
Contact: John Ellerton, MD    702-822-2000      
HealthCare Partners Medical Group Oncology/Hematology-San Martin Recruiting
Las Vegas, Nevada, United States, 89113
Contact: John Ellerton, MD    702-822-2000      
Radiation Oncology Centers of Nevada Southeast Recruiting
Las Vegas, Nevada, United States, 89119
Contact: John Ellerton, MD    702-822-2000      
Cancer Therapy and Integrative Medicine Recruiting
Las Vegas, Nevada, United States, 89121
Contact: John Ellerton, MD    702-822-2000      
21st Century Oncology-Vegas Tenaya Recruiting
Las Vegas, Nevada, United States, 89128
Contact: John Ellerton, MD    702-822-2000      
Cancer and Blood Specialists-Tenaya Recruiting
Las Vegas, Nevada, United States, 89128
Contact: John Ellerton, MD    702-822-2000      
Comprehensive Cancer Centers of Nevada-Northwest Recruiting
Las Vegas, Nevada, United States, 89128
Contact: John Ellerton, MD    702-822-2000      
HealthCare Partners Medical Group Oncology/Hematology-Tenaya Recruiting
Las Vegas, Nevada, United States, 89128
Contact: John Ellerton, MD    702-822-2000      
Comprehensive Cancer Centers of Nevada-Summerlin Recruiting
Las Vegas, Nevada, United States, 89144
Contact: John Ellerton, MD    702-822-2000      
Cancer and Blood Specialists-Fort Apache Recruiting
Las Vegas, Nevada, United States, 89148
Contact: John Ellerton, MD    702-822-2000      
Comprehensive Cancer Centers of Nevada Recruiting
Las Vegas, Nevada, United States, 89148
Contact: John Ellerton, MD    702-822-2000      
Las Vegas Cancer Center-Medical Center Recruiting
Las Vegas, Nevada, United States, 89148
Contact: John Ellerton, MD    702-822-2000      
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Recruiting
Las Vegas, Nevada, United States, 89149
Contact: John Ellerton, MD    702-822-2000      
Nevada Cancer Research Foundation NCORP Recruiting
Las Vegas, Nevada, United States, 89106
Contact: John Ellerton, MD    702-384-0808      
United States, New Hampshire
Dartmouth Hitchcock Medical Center Recruiting
Lebanon, New Hampshire, United States, 03756
Contact: Kari Rosenkranz, MD    800-639-6918      
United States, New Jersey
Memorial Sloan Kettering Cancer Center-Basking Ridge Recruiting
Basking Ridge, New Jersey, United States, 07920
Contact: Kimberly Van Zee, MD    646-888-5362      
Saint Peter's University Hospital Recruiting
New Brunswick, New Jersey, United States, 08901
Contact: Susan McManus, MD    732-745-8600 ext 6163      
United States, New Mexico
University of New Mexico Cancer Center Recruiting
Albuquerque, New Mexico, United States, 87102
Contact: Calvin Ridgeway, MD    505-727-6900      
Lovelace Women's Hospital Recruiting
Albuquerque, New Mexico, United States, 87109
Contact: Calvin Ridgeway, MD    505-559-6100      
United States, New York
Memorial Sloan Kettering Cancer Center-Commack Recruiting
Commack, New York, United States, 11725
Contact: Kimberly Van Zee, MD    646-888-5362      
North Shore University Hospital Recruiting
Manhasset, New York, United States, 11030
Contact: Dominic Filardi, MD    516-487-9454      
North Shore-LIJ Health System/Center for Advanced Medicine Recruiting
New Hyde Park, New York, United States, 11040
Contact: Dominic Filardi, MD    516-487-9454      
Memorial Sloan Kettering Cancer Center Recruiting
New York, New York, United States, 10065
Contact: Kimberly Van Zee, MD    646-888-5362      
Vassar Brothers Medical Center Recruiting
Poughkeepsie, New York, United States, 12601
Contact: Gregory Zanieski, M.D.    845-483-6483      
University of Rochester Recruiting
Rochester, New York, United States, 14642
Contact: Kristin Skinner, MD    585-275-5830      
Memorial Sloan Kettering Cancer Center-Rockville Centre Recruiting
Rockville Centre, New York, United States, 11570
Contact: Kimberly Van Zee, MD    646-888-5362      
Memorial Sloan Kettering Cancer Center-Sleepy Hollow Recruiting
Sleepy Hollow, New York, United States, 10591
Contact: Kimberly Van Zee, MD    646-888-5362      
Memorial Sloan Kettering Cancer Center-West Harrison Recruiting
West Harrison, New York, United States, 10604
Contact: Kimberly Van Zee, MD    646-888-5362      
United States, North Carolina
Randolph Hospital Recruiting
Asheboro, North Carolina, United States, 27203
Contact: Faera Byerly, MD    336-274-8444      
Carolinas Medical Center/Levine Cancer Institute Recruiting
Charlotte, North Carolina, United States, 28203
Contact: Richard White, MD    704-355-3809      
Levine Cancer Institute-Tryon Recruiting
Charlotte, North Carolina, United States, 28203
Contact: Richard White, MD    980-442-6356      
Novant Health Presbyterian Medical Center Recruiting
Charlotte, North Carolina, United States, 28204
Contact: Justin Favaro, MD    704-342-1900      
Carolina Surgical Clinic of Charlotte PA Recruiting
Charlotte, North Carolina, United States, 28207
Contact: Justin Favaro, MD    704-342-1900      
Oncology Specialists of Charlotte Recruiting
Charlotte, North Carolina, United States, 28207
Contact: Justin Favaro, MD    704-342-1900      
Carolinas Medical Center/Levine Cancer Institute-Pineville Recruiting
Charlotte, North Carolina, United States, 28210
Contact: Richard White, MD    980-442-6356      
Carolinas Medical Center/Levine Cancer Institute-University Recruiting
Charlotte, North Carolina, United States, 28262
Contact: Richard White, MD    980-442-6356      
Southern Oncology Specialists-Charlotte Recruiting
Charlotte, North Carolina, United States, 28262
Contact: Justin Favaro, MD    704-342-1900      
Levine Cancer Institute-Ballantyne Recruiting
Charlotte, North Carolina, United States, 28277
Contact: Richard White, MD    980-442-6356      
CaroMont Breast Surgical Specialists-Gastonia Recruiting
Gastonia, North Carolina, United States, 28054
Contact: Paula Lundgren, MD    704-671-7390      
CaroMont Regional Medical Center Recruiting
Gastonia, North Carolina, United States, 28054
Contact: Paula Lundgren, MD    704-671-7390      
Cone Health Cancer Center Recruiting
Greensboro, North Carolina, United States, 27403
Contact: Faera Byerly, MD    336-274-8444      
Southern Oncology Specialists-Huntersville Recruiting
Huntersville, North Carolina, United States, 28078
Contact: Justin Favaro, MD    704-342-1900      
Lake Norman Hematology Oncology Specialists-Huntersville Recruiting
Huntersville, North Carolina, United States, 28078
Contact: Justin Favaro, MD    704-342-1900      
Matthews Radiation Oncology Center Recruiting
Matthews, North Carolina, United States, 28105
Contact: Justin Favaro, MD    704-342-1900      
Novant Health Cancer Specialists-Matthews Recruiting
Matthews, North Carolina, United States, 28105
Contact: Justin Favaro, MD    704-342-1900      
Carolinas HealthCare System Union Recruiting
Monroe, North Carolina, United States, 28112
Contact: Richard White, MD    980-442-6356      
Lake Norman Hematology Oncology Specialists-Mooresville Recruiting
Mooresville, North Carolina, United States, 28117
Contact: Justin Favaro, MD    704-342-1900      
Annie Penn Memorial Hospital Recruiting
Reidsville, North Carolina, United States, 27320
Contact: Faera Byerly, MD    336-274-8444      
United States, Ohio
Strecker Cancer Center-Belpre Recruiting
Belpre, Ohio, United States, 45714
Contact: John Kuebler, MD    614-566-3275      
Adena Regional Medical Center Recruiting
Chillicothe, Ohio, United States, 54601
Contact: John Kuebler, MD    614-566-3275      
Good Samaritan Hospital-Cincinnati Recruiting
Cincinnati, Ohio, United States, 45220
Contact: Mehmet Copur, MD    308-398-5450      
The Christ Hospital Recruiting
Cincinnati, Ohio, United States, 45219
Contact: Jennifer Manders, MD    513-585-1496      
Bethesda North Hospital Recruiting
Cincinnati, Ohio, United States, 45242
Contact: Mehmet Copur, MD    308-398-5450      
TriHealth Cancer Institute-Westside Recruiting
Cincinnati, Ohio, United States, 45247
Contact: Mehmet Copur, MD    308-398-5450      
TriHealth Cancer Institute-Anderson Recruiting
Cincinnati, Ohio, United States, 45255
Contact: Mehmet Copur, MD    308-398-5450      
University of Cincinnati Recruiting
Cincinnati, Ohio, United States, 45267
Contact: Elizabeth Shaughnessy, MD    513-558-0414      
Doctors Hospital Recruiting
Columbus, Ohio, United States, 43228
Contact: John Kuebler, MD    614-566-3275      
Columbus Oncology and Hematology Associates Inc Recruiting
Columbus, Ohio, United States, 43214
Contact: John Kuebler, MD    614-488-2118      
Riverside Methodist Hospital Recruiting
Columbus, Ohio, United States, 43214
Contact: John Kuebler, MD    614-566-3275      
Columbus NCI Community Oncology Research Program Recruiting
Columbus, Ohio, United States, 43215
Contact: John Kuebler, MD    614-566-3275      
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: John Kuebler, MD    614-566-3275      
The Mark H Zangmeister Center Recruiting
Columbus, Ohio, United States, 43219
Contact: John Kuebler, MD    614-566-3275      
Mount Carmel Health Center West Recruiting
Columbus, Ohio, United States, 43222
Contact: John Kuebler, MD    614-566-3275      
Mount Carmel East Hospital Recruiting
Columbus, Ohio, United States, 43213
Contact: John Kuebler, MD    614-566-3275      
Delaware Health Center-Grady Cancer Center Recruiting
Delaware, Ohio, United States, 43015
Contact: John Kuebler, MD    614-488-2118      
Delaware Radiation Oncology Recruiting
Delaware, Ohio, United States, 43015
Contact: John Kuebler, MD    614-488-2118      
Grady Memorial Hospital Recruiting
Delaware, Ohio, United States, 43015
Contact: John Kuebler, MD    614-566-3275      
Fairfield Medical Center Recruiting
Lancaster, Ohio, United States, 43130
Contact: John Kuebler, MD    614-488-2118      
OhioHealth MedCentral Hospital Recruiting
Mansfield, Ohio, United States, 44903
Contact: John Kuebler, MD    614-566-3275      
Marietta Memorial Hospital Recruiting
Marietta, Ohio, United States, 45750
Contact: John Kuebler, MD    614-566-3275      
OhioHealth Marion General Hospital Recruiting
Marion, Ohio, United States, 43302
Contact: John Kuebler, MD    614-566-3275      
Knox Community Hospital Recruiting
Mount Vernon, Ohio, United States, 43050
Contact: John Kuebler, MD    614-488-2118      
Newark Radiation Oncology Recruiting
Newark, Ohio, United States, 43055
Contact: John Kuebler, MD    614-488-2118      
Licking Memorial Hospital Recruiting
Newark, Ohio, United States, 43055
Contact: John Kuebler, MD    614-566-3275      
Southern Ohio Medical Center Recruiting
Portsmouth, Ohio, United States, 45662
Contact: John Kuebler, MD    614-566-3275      
Springfield Regional Medical Center Recruiting
Springfield, Ohio, United States, 45505
Contact: John Kuebler, MD    614-566-3275      
University Pointe Recruiting
West Chester, Ohio, United States, 45069
Contact: Elizabeth Shaughnessy, MD    513-558-0414      
Saint Ann's Hospital Recruiting
Westerville, Ohio, United States, 43081
Contact: John Kuebler, MD    614-566-3275      
Genesis Healthcare System Cancer Care Center Recruiting
Zanesville, Ohio, United States, 43701
Contact: John Kuebler, MD    614-566-3275      
United States, Oklahoma
Mercy Hospital Oklahoma City Recruiting
Oklahoma City, Oklahoma, United States, 73120
Contact: Alan Hollingsworth, MD    405-936-5455      
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: William Dooley, MD    405-271-4272      
United States, Oregon
Oregon Health and Science University Recruiting
Portland, Oregon, United States, 97239
Contact: Charlotte Kubicky, MD    503-494-1080      
United States, Pennsylvania
Lehigh Valley Hospital-Cedar Crest Recruiting
Allentown, Pennsylvania, United States, 18103
Contact: Suresh Nair, MD    610-402-7880      
Lehigh Valley Hospital-Muhlenberg Recruiting
Bethlehem, Pennsylvania, United States, 18017
Contact: Suresh Nair, MD    610-402-7880      
Bryn Mawr Hospital Recruiting
Bryn Mawr, Pennsylvania, United States, 19010
Contact: Albert DeNittis, MD    484-476-2433      
University of Pittsburgh Cancer Institute (UPCI) Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Gretchen Ahrendt, MD    412-647-2811      
Lankenau Medical Center Recruiting
Wynnewood, Pennsylvania, United States, 19096
Contact: Albert DeNittis, MD    484-476-2433      
United States, Rhode Island
Roger Williams Medical Center Recruiting
Providence, Rhode Island, United States, 02908
Contact: James Koness, MD    401-456-2268      
United States, South Carolina
Hilton Head Regional Medical Center Recruiting
Hilton Head Island, South Carolina, United States, 29926
Contact: Rochelle Ringer, MD    843-876-0179      
Levine Cancer Institute-Rock Hill Recruiting
Rock Hill, South Carolina, United States, 29732
Contact: Richard White, MD    980-442-6356      
Lexington Medical Center Recruiting
West Columbia, South Carolina, United States, 29169
Contact: Lynn Tucker, MD    803-791-2000      
United States, South Dakota
Avera Cancer Institute Recruiting
Sioux Falls, South Dakota, United States, 57105
Contact: Wade Dosch, MD    605-328-1367      
United States, Tennessee
Memorial Hospital Recruiting
Chattanooga, Tennessee, United States, 37404
Contact: Mehmet Copur, MD    308-398-5450      
Pulmonary Medicine Center of Chattanooga-Hixson Recruiting
Hixson, Tennessee, United States, 37343
Contact: Mehmet Copur, MD    308-398-5450      
Memorial GYN Plus Recruiting
Ooltewah, Tennessee, United States, 37363
Contact: Mehmet Copur, MD    308-398-5450      
United States, Texas
Texas Tech University Health Sciences Center-Amarillo Recruiting
Amarillo, Texas, United States, 79106
Contact: Rakhshanda Rahman, MD    806-354-5437      
Parkland Memorial Hospital Recruiting
Dallas, Texas, United States, 75235
Contact: Ann Leitch, MD    214-648-5890      
UT Southwestern/Simmons Cancer Center-Dallas Recruiting
Dallas, Texas, United States, 75390
Contact: Ann Leitch, MD    214-648-5890      
M. D. Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Elizabeth Mittendorf, MD    713-792-2362      
The Methodist Hospital System Recruiting
Houston, Texas, United States, 77030
Contact: Barbara Bass, MD    713-441-5132      
Doctor's Hospital of Laredo Recruiting
Laredo, Texas, United States, 78045
Contact: Gary Unzeitig, MD    956-726-3691      
United States, Utah
Huntsman Cancer Institute/University of Utah Recruiting
Salt Lake City, Utah, United States, 84112
Contact: Matthew Poppe, MD    801-581-2396      
United States, Vermont
Central Vermont Medical Center Recruiting
Berlin, Vermont, United States, 05602
Contact: Michelle Sowden, MD    802-656-8990      
University of Vermont College of Medicine Recruiting
Burlington, Vermont, United States, 05405
Contact: Michelle Sowden, MD    802-656-8990      
Norris Cotton Cancer Center-North Recruiting
Saint Johnsbury, Vermont, United States, 05819
Contact: Michelle Rosenkranz, MD    603-650-9479      
United States, Virginia
Mary Washington Hospital Recruiting
Fredericksburg, Virginia, United States, 22401
Contact: Laurie Cuttino, MD    804-828-7232      
Virginia Commonwealth University/Massey Cancer Center Recruiting
Richmond, Virginia, United States, 23298
Contact: Laurie Cuttino, MD    804-828-7232      
United States, Washington
Harrison HealthPartners Hematology and Oncology-Bremerton Recruiting
Bremerton, Washington, United States, 98310
Contact: Mehmet Copur, MD    308-398-5450      
Harrison Medical Center Recruiting
Bremerton, Washington, United States, 98310
Contact: Mehmet Copur, MD    308-398-5450      
Highline Medical Center-Main Campus Recruiting
Burien, Washington, United States, 98166
Contact: Mehmet Copur, MD    308-398-5450      
Saint Elizabeth Hospital Recruiting
Enumclaw, Washington, United States, 98022
Contact: Mehmet Copur, MD    308-398-5450      
Saint Francis Hospital Recruiting
Federal Way, Washington, United States, 98003
Contact: Mehmet Copur, MD    308-398-5450      
Saint Clare Hospital Recruiting
Lakewood, Washington, United States, 98499
Contact: Mehmet Copur, MD    308-398-5450      
Harrison HealthPartners Hematology and Oncology-Poulsbo Recruiting
Poulsbo, Washington, United States, 98370
Contact: Mehmet Copur, MD    308-398-5450      
Virginia Mason Medical Center Recruiting
Seattle, Washington, United States, 98101
Contact: Janie Margenthaler, MD    314-362-7534      
Franciscan Research Center-Northwest Medical Plaza Recruiting
Tacoma, Washington, United States, 98405
Contact: Mehmet Copur, MD    308-398-5450      
Northwest Medical Specialties PLLC Recruiting
Tacoma, Washington, United States, 98405
Contact: Mehmet Copur, MD    308-398-5450      
United States, Wisconsin
Aurora BayCare Medical Center Recruiting
Green Bay, Wisconsin, United States, 54311-6519
Contact: William Owens, MD    800-252-2990      
Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Anthony Jaslowski, MD    920-884-3135      
Green Bay Oncology Limited at Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Anthony Jaslowski, MD    920-884-3135      
Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Anthony Jaslowski, MD    920-884-3135      
Green Bay Oncology at Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Anthony Jaslowski, MD    920-884-3135      
Gundersen Lutheran Medical Center Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Jeanne Johnson, MD    608-782-7300      
Aurora Saint Luke's Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53215
Contact: Judy Tjoe, MD    800-252-2990      
Froedtert and the Medical College of Wisconsin Recruiting
Milwaukee, Wisconsin, United States, 53226
Contact: Tina Yen, MD    414-805-4380      
Aurora Sinai Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53233
Contact: Judy Tjoe, MD    800-252-2990      
Westfields Hospital/Cancer Center of Western Wisconsin Recruiting
New Richmond, Wisconsin, United States, 54017
Contact: Daniel Anderson, MD    952-993-1517      
Vince Lombardi Cancer Clinic-Oshkosh Recruiting
Oshkosh, Wisconsin, United States, 54904
Contact: William Owens, MD    800-252-2990      
Aurora Medical Center in Summit Recruiting
Summit, Wisconsin, United States, 53066
Contact: William Owens, MD    800-252-2990      
Aurora West Allis Medical Center Recruiting
West Allis, Wisconsin, United States, 53227
Contact: Judy Tjoe, MD    800-252-2990      
United States, Wyoming
Big Horn Basin Cancer Center Recruiting
Cody, Wyoming, United States, 82414
Contact: Benjamin Marchello, MD    406-237-5460      
Billings Clinic-Cody Recruiting
Cody, Wyoming, United States, 82414
Contact: Benjamin Marchello, MD    406-237-5460      
Welch Cancer Center Recruiting
Sheridan, Wyoming, United States, 82801
Contact: Benjamin Marchello, MD    406-238-6290      
Sponsors and Collaborators
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)
Investigators
Study Chair: Judy Boughey, MD Mayo Clinic
  More Information

Additional Information:
Responsible Party: Alliance for Clinical Trials in Oncology
ClinicalTrials.gov Identifier: NCT01556243     History of Changes
Other Study ID Numbers: ACOSOG-Z11102  CDR0000728605 
Study First Received: March 15, 2012
Last Updated: June 17, 2016
Health Authority: United States: NCI Institutional Review Board

Keywords provided by Alliance for Clinical Trials in Oncology:
stage IA breast cancer
stage IB breast cancer
stage II breast cancer
ductal breast carcinoma in situ
lobular breast carcinoma in situ

Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Skin Diseases

ClinicalTrials.gov processed this record on July 21, 2016