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Trial record 1 of 1 for:    NCT01471522
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International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) (ISCHEMIA)

This study is currently recruiting participants. (see Contacts and Locations)
Verified October 2016 by New York University School of Medicine
New York University
Stanford University
National Heart, Lung, and Blood Institute (NHLBI)
Albany Stratton VA Medical Center
Cedars-Sinai Medical Center
Columbia University
Duke University
East Carolina University
Emory University
Harvard University
Massachusetts General Hospital
Montreal Heart Institute
University of British Columbia
University of Missouri, Kansas City
Vanderbilt University
Information provided by (Responsible Party):
New York University School of Medicine Identifier:
First received: November 10, 2011
Last updated: October 13, 2016
Last verified: October 2016

The purpose of the ISCHEMIA trial is to determine the best management strategy for higher-risk patients with stable ischemic heart disease. This is a multicenter randomized controlled trial with a target enrollment of ~5000 patients with at least moderate ischemia on stress imaging. Patients will be assigned at random to a routine invasive strategy (INV) with cardiac catheterization (cath) followed by revascularization plus optimal medical therapy (OMT) or to a conservative strategy (CON) of OMT, with cath and revascularization reserved for those who fail OMT.


A. Primary Aim The primary aim of the ISCHEMIA trial is to determine whether an initial invasive strategy of cardiac catheterization followed by optimal revascularization, if feasible, in addition to OMT, will reduce the primary composite endpoint of cardiovascular death or nonfatal myocardial infarction in participants with SIHD and at least moderate ischemia over an average follow-up of approximately 4 years compared with an initial conservative strategy of OMT alone with catheterization reserved for failure of OMT. The primary endpoint is time to centrally adjudicated cardiovascular death or nonfatal myocardial infarction.

B. Secondary Aims Major: To compare angina-related quality of life between groups. Other secondary aims include: a) comparing the incidence of all-cause death; the components of the primary endpoint; the composite endpoint of cardiovascular death, myocardial infarction, or hospitalization for unstable angina, resuscitated cardiac arrest, or heart failure; stroke; and stroke combined with cardiovascular death, myocardial infarction, or hospitalization for unstable angina, resuscitated cardiac arrest, or heart failure between randomized groups; and b) comparing health resource utilization, costs, and cost-effectiveness between groups.

Condition: Coronary Disease Procedure: Coronary CT Angiogram Procedure: Cardiac catheterization Phase: Phase III

Condition: Cardiovascular Diseases Procedure: Angioplasty, Transluminal, Percutaneous Coronary, other catheter-based interventions Phase: Phase III

Condition: Heart Diseases Procedure: Coronary Artery Bypass Surgery Phase: Phase III

Condition Intervention
Cardiovascular Diseases
Coronary Disease
Coronary Artery Disease
Heart Diseases
Myocardial Ischemia
Procedure: cardiac catheterization
Procedure: coronary artery bypass graft surgery
Procedure: percutaneous coronary intervention
Behavioral: Lifestyle
Drug: Medication

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

Resource links provided by NLM:

Further study details as provided by New York University School of Medicine:

Primary Outcome Measures:
  • Time to first occurrence of cardiovascular death or nonfatal myocardial infarction. [ Time Frame: ~four year follow-up ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Angina control per Seattle Angina Questionnaire (SAQ) Angina Frequency Scale [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Disease specific quality of life per Seattle Angina Questionnaire (SAQ) Quality of Life Scale [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Composite of cardiovascular death, nonfatal myocardial infarction, resuscitated cardiac arrest, or hospitalization for unstable angina or heart failure [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Cardiovascular death [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Nonfatal myocardial infarction [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Resuscitated cardiac arrest [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Hospitalization for unstable angina [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Hospitalization for heart failure [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Stroke [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Composite of cardiovascular death, nonfatal myocardial infarction, stroke, resuscitated cardiac arrest, hospitalization for unstable angina or heart failure. [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]
  • Health resource utilization, costs, and cost effectiveness [ Time Frame: mean ~four year follow-up ] [ Designated as safety issue: No ]

Estimated Enrollment: 5000
Study Start Date: July 2012
Estimated Study Completion Date: December 2018
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Invasive Strategy (INV)
Routine invasive strategy with cardiac catheterization followed by revascularization plus optimal medical therapy.
Procedure: cardiac catheterization
Narrowed blood vessels can be opened without surgery using stents or can be bypassed with surgery. To determine which is the best approach for you the doctor needs to look at your blood vessels to see where the narrowings are and how much narrowing there is. This is done by a procedure known as a cardiac catheterization.
Other Name: cath
Procedure: coronary artery bypass graft surgery
Artery narrowing is bypassed during surgery with a healthy artery or vein from another part of the body. This is known as coronary artery bypass grafting, or CABG (said, "cabbage"). The surgery creates new routes around narrowed and blocked heart arteries. This allows more blood flow to the heart.
Other Name: CABG
Procedure: percutaneous coronary intervention
Percutaneous coronary intervention may be done as part of the cardiac catheterization procedure. With this procedure a small, hollow, mesh tube (stent) is inserted into the narrowed part of the artery. The stent pushes the plaque against the artery wall, and opens the vessel to allow better blood flow.
Other Name: PCI
Behavioral: Lifestyle
diet, physical activity, smoking cessation
Other Name: Behavior change
Drug: Medication
antiplatelet, statin, other lipid lowering, antihypertensive, and anti-ischemic medical therapies
Other Name: Pharmacologic Therapy
Active Comparator: Conservative Strategy
Optimal medical therapy with cardiac catheterization and revascularization reserved for patients with acute coronary syndrome, ischemic heart failure, resuscitated cardiac arrest or refractory symptoms.
Behavioral: Lifestyle
diet, physical activity, smoking cessation
Other Name: Behavior change
Drug: Medication
antiplatelet, statin, other lipid lowering, antihypertensive, and anti-ischemic medical therapies
Other Name: Pharmacologic Therapy

  Show Detailed Description


Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • At least moderate ischemia on an ischemia test
  • Participant is willing to comply with all aspects of the protocol, including adherence to the assigned strategy, medical therapy and follow-up visits
  • Participant is willing to give written informed consent
  • Age ≥ 21 years

Exclusion Criteria:

  • LVEF < 35%
  • History of unprotected left main stenosis >50% on prior coronary computed tomography angiography (CCTA) or prior cardiac catheterization (if available)
  • Finding of "no obstructive CAD" (<50% stenosis in all major epicardial vessels) on prior CCTA or prior catheterization, performed within 12 months
  • Coronary anatomy unsuitable for either PCI or CABG
  • Unacceptable level of angina despite maximal medical therapy
  • Very dissatisfied with medical management of angina
  • History of noncompliance with medical therapy
  • Acute coronary syndrome within the previous 2 months
  • PCI within the previous 12 months
  • Stroke within the previous 6 months or spontaneous intracranial hemorrhage at any time
  • History of ventricular tachycardia requiring therapy for termination, or symptomatic sustained ventricular tachycardia not due to a transient reversible cause
  • NYHA class III-IV heart failure at entry or hospitalization for exacerbation of chronic heart failure within the previous 6 months
  • Non-ischemic dilated or hypertrophic cardiomyopathy
  • End stage renal disease on dialysis or estimated glomerular filtration rate (eGFR) <30mL/min (not an exclusion criterion for CKD ancillary trial, see CKD ancillary trial, Section 18)
  • Severe valvular disease or valvular disease likely to require surgery or percutaneous valve replacement during the trial
  • Allergy to radiographic contrast that cannot be adequately pre-medicated, or any prior anaphylaxis to radiographic contrast
  • Planned major surgery necessitating interruption of dual antiplatelet therapy (note that patients may be eligible after planned surgery)
  • Life expectancy less than the duration of the trial due to non-cardiovascular comorbidity
  • Pregnancy (known to be pregnant; to be confirmed before CCTA and/or randomization, if applicable)
  • Patient who, in the judgment of the patient's physician, is likely to have significant unprotected left main stenosis (Those who are able to undergo CCTA will have visual assessment of the left main coronary artery by the CCTA core lab)
  • Enrolled in a competing trial that involves a non-approved cardiac drug or device
  • Inability to comply with the protocol
  • Exceeds the weight or size limit for CCTA or cardiac catheterization at the site
  • Canadian Cardiovascular Society Class III angina of recent onset, OR angina of any class with a rapidly progressive or accelerating pattern
  • Canadian Cardiovascular Society Class IV angina, including unprovoked rest angina
  • High risk of bleeding which would contraindicate the use of dual antiplatelet therapy
  • Cardiac transplant recipient
  • Prior CABG, unless CABG was performed more than 12 months ago, and coronary anatomy has been demonstrated to be suitable for PCI or repeat CABG to accomplish complete revascularization of ischemic areas (CCC approval required)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01471522

Contact: Judith S Hochman, MD 212-263-4225
Contact: Stephanie Mavromichalis 212-263-4225

  Hide Study Locations
United States, Alabama
University of Alabama at Birmingham Recruiting
Birmingham, Alabama, United States, 35294
Contact: Fadi Hege   
United States, Arizona
Scottsdale Healthcare Withdrawn
Scottsdale, Arizona, United States, 85258
Yuma Regional Medical Center Recruiting
Yuma, Arizona, United States
Contact: Mohammed Al-Amoodi   
United States, California
Cedars Sinai Medical Center Terminated
Beverly Hills, California, United States, 90211
John Muir Health Withdrawn
Concord, California, United States, 94520
UCSF - Fresno Community Regional Medical Center Recruiting
Fresno, California, United States
Contact: Prakash Deedwania   
Alliance Clinical Research Terminated
Laguna Hills, California, United States, 92653
UCLA Medical Center Recruiting
Los Angeles, California, United States, 90095
Contact: Gabriel Vorobiof   
University of Southern California Recruiting
Los Angeles, California, United States
Contact: Farhood Saremi   
University of California Irvine Medical Center Recruiting
Orange, California, United States
Contact: Mayil Krishnam   
Palo Alto Medical Foundation Research Institute Recruiting
Palo Alto, California, United States, 94087`
Contact: bob Hu   
Kaiser Permanente- San Jose Recruiting
San Jose, California, United States, 94538
Contact: James Jang   
Coastal Heart Medical Group Recruiting
Santa Ana, California, United States
Contact: Amer Zarka   
Torrance Memorial Medical Center Recruiting
Torrance, California, United States, 90505
Contact: Ray Wyman   
United States, Colorado
Empirican PRN LLC Recruiting
Denver, Colorado, United States
Contact: David Avino   
South Denver Cardiology Associates, PC Recruiting
Littleton, Colorado, United States, 80120
Contact: Ira Dauber   
Medical Center of the Rockies Recruiting
Loveland, Colorado, United States, 80538
Contact: Thomas Downes   
United States, Connecticut
West Haven VA Medical Center Recruiting
W Haven, Connecticut, United States
Contact: Judith Meadows   
United States, Delaware
Nanticoke Cardiology Associates Terminated
Seaford, Delaware, United States, 19973
United States, Florida
Daytona Heart Group Recruiting
Daytona Beach, Florida, United States, 32114
Contact: Glenn Rayos   
Malcom Randall V.A. Medical Center Recruiting
Gainesville, Florida, United States, 32608
Contact: David Wichester   
University of Florida Withdrawn
Gainesville, Florida, United States, 32610
Mayo Clinic Recruiting
Jacksonville, Florida, United States
Contact: Jorge Trejo-Gutierrez   
Mercy Hospital Withdrawn
Miami, Florida, United States, 33133
Cardiovascular Center of Sarasota Recruiting
Sarasota, Florida, United States, 34239
Contact: Mahfouz El Shahawy   
Sarasota Memorial Hospital Recruiting
Sarasota, Florida, United States, 34239
Contact: Michael Mumma   
University of South Florida Recruiting
Tampa, Florida, United States, 33606
Contact: Arthur Labovitz   
United States, Georgia
Emory University Recruiting
Atlanta, Georgia, United States, 30322
Contact: Arshed Quyyumi   
Saint Joseph's Hospital of Atlanta Terminated
Atlanta, Georgia, United States, 30342
Atlanta V.A. Medical Center Recruiting
Decatur, Georgia, United States, 30033
Contact: Kreton Mavromatis   
United States, Illinois
University of Chicago Medical Center Withdrawn
Chicago, Illinois, United States, 60637
Loyola University Medical Center Recruiting
Maywood, Illinois, United States, 60153
Contact: Khaled Dajani   
United States, Indiana
Indiana University / Krannert Institute of Cardiology Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Ronald Mastouri   
United States, Iowa
Midwest Cardiovascular Research Foundation Recruiting
Davenport, Iowa, United States
Contact: Nicolas Shammas   
Iowa Heart Center Recruiting
Iowa City, Iowa, United States, 52242
Contact: Gardar Sigurdsson   
United States, Kentucky
University of Kentucky Hospital Recruiting
Lexington, Kentucky, United States, 40536
Contact: David Booth   
V.A. Medical Center - Lexington Recruiting
Lexington, Kentucky, United States
Contact: David Booth   
University of Louisville Recruiting
Louisville, Kentucky, United States
Contact: Rita Coram       ISCHEMIA <>   
United States, Louisiana
Cardiovascular Specialists of Southwest Louisiana, LLC Recruiting
Lake Charles, Louisiana, United States
Contact: Michael Turner       ISCHEMIA <>   
United States, Maryland
University of Maryland Recruiting
Baltimore, Maryland, United States, 21201
Contact: James Stafford         
NIH Heart Center at Suburban Hospital Recruiting
Bethesda, Maryland, United States, 20814
Contact: Greg Kumkumian   
Walter Reed National Military Medical Center Recruiting
Bethesda, Maryland, United States
Contact: Matthew Jezior         
United States, Massachusetts
Brigham and Women's Hospital Recruiting
Boston, Massachusetts, United States, 02115
Contact: Peter Stone   
Boston Medical Center Recruiting
Boston, Massachusetts, United States, 02118
Contact: Claudia Hochberg   
VA Boston Healthcare System Recruiting
West Roxbury, Massachusetts, United States, 02132
Contact: Scott Kinlay   
Saint Vincent Hospital at Worcester Medical Center Recruiting
Worcester, Massachusetts, United States, 01608
Contact: Joseph Hannan   
United States, Michigan
Henry Ford Health System Recruiting
Detroit, Michigan, United States, 48202
Contact: Khaled Nour   
Spectrum Health Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: David Wohns   
McLaren Northern Michigan Recruiting
Petoskey, Michigan, United States
Contact: Andrew Teklinski   
William Beaumont Health Systems Withdrawn
Royal Oak, Michigan, United States, 48073
Covenant Medical Center Recruiting
Saginaw, Michigan, United States, 48602
Contact: Scott Martin   
Providence Hospital and Medical Center Recruiting
Southfield, Michigan, United States
Contact: Souheil Saba   
Beaumont Hospital Withdrawn
Troy, Michigan, United States, 48085
Michigan Heart, PC Recruiting
Ypsilanti, Michigan, United States, 48197
Contact: Herbert Aronow   
United States, Minnesota
University of Minnesota Terminated
Minneapolis, Minnesota, United States, 55455
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States
Contact: Charles Herzog   
Minneapolis V.A. Medical Center Recruiting
Minneapolis, Minnesota, United States
Contact: Edward McFalls       ISCHEMIA <>   
Mayo Clinic Recruiting
Rochester, Minnesota, United States, 55905
Contact: Todd Miller   
HealthEast Saint Joseph's Hospital Recruiting
St. Paul, Minnesota, United States
Contact: Dayuan Li   
United States, Missouri
Saint Luke's Hospital Recruiting
Kansas City, Missouri, United States, 64111
Contact: James O'Keefe   
Kansas City V.A. Medical Center Recruiting
Kansas City, Missouri, United States
Contact: Rajat Barua   
United States, New Jersey
Englewood Hospital and Medical Center Recruiting
Englewood, New Jersey, United States, 07631
Contact: Richard Goldweit   
North Shore University Hospital Recruiting
Manhasset, New Jersey, United States, 11030
Contact: Bruce Rutkin   
Robert Wood Johnson Medical School Recruiting
New Brunswick, New Jersey, United States
Contact: John Kostis       ISCHEMIA <>   
AtlantiCare Regional Medical Center Recruiting
Pomona, New Jersey, United States, 08240
Contact: Kevin Marzo   
The Valley Hospital Terminated
Ridgewood, New Jersey, United States, 07450
Hackensack University Medical Cetner Recruiting
Saddle Brook, New Jersey, United States, 07663
Contact: William Salerno   
United States, New York
Albany Associates in Cardiology Withdrawn
Albany, New York, United States, 12205
Albany Medical Center Hospital Recruiting
Albany, New York, United States, 12208
Contact: Mohammad El-Hajjar   
Capital Cardiology Associates Recruiting
Albany, New York, United States, 12211
Contact: Lance Sullenberger   
Samuel Stratton VA Medical Center Recruiting
Albany, New York, United States
Contact: Mohammad El-Hajjar   
NYU-HHC Lincoln Medical and Mental Health Center Recruiting
Bronx, New York, United States, 10451
Contact: Lekshmi Dharmarajan   
Jacobi Medical Center Recruiting
Bronx, New York, United States, 10461
Contact: Jay Meisner   
Montefiore Medical Center Withdrawn
Bronx, New York, United States, 10467
NYU-HHC Kings County Hospital Center Recruiting
Brooklyn, New York, United States, 11203
Contact: Ronald Pedalino   
New York Methodist Hospital Recruiting
Brooklyn, New York, United States, 11215
Contact: John Heitner   
Woodhull Hospital Recruiting
Brooklyn, New York, United States, 11229
Contact: Ronny Cohen   
Empirican PRN LLC / Advanced Cardiology Group Recruiting
Buffalo, New York, United States
Contact: Bruce Platt   
NYU Hudson Valley Cardiology Recruiting
Cortlandt Manor, New York, United States, 10567
Contact: Glenn Hamroff   
New York University - Langone Cardiovascular Associates Recruiting
Flushing, New York, United States
Contact: Joseph Wiesel       ISCHEMIA <>   
Mid Valley Cardiology Recruiting
Kingston, New York, United States
Contact: Ellis Lader   
Winthrop University Hospital Recruiting
Mineola, New York, United States, 11501
Contact: Kevin Marzo   
New York University School of Medicine Recruiting
New York, New York, United States, 10016
Contact: Harmony R Reynolds, MD    212-263-4225   
Principal Investigator: Harmony R Reynolds, MD         
NYU New York Medical Associates Recruiting
New York, New York, United States, 10022
Contact: Dennis Goodman   
Saint Luke's-Roosevelt Hospital Center Recruiting
New York, New York, United States, 10025
Contact: Jacqueline Tamis-Holland   
Mount Sinai School of Medicine Recruiting
New York, New York, United States, 10029
Contact: Robert Pyo   
Columbia University Medical Center Recruiting
New York, New York, United States, 10032
Contact: Sabahat Bokhari   
Beth Israel Medical Center Recruiting
New York, New York, United States
Contact: Kenneth Giedd   
V.A. New York Harbor Healthcare System - Manhattan Campus Recruiting
New York, New York, United States
Contact: Steven Sedlis   
Lenox Hill Hospital Withdrawn
New, New York, United States, 10075
Cardiology Associates of Schenectady P.C. Recruiting
Schenectady, New York, United States, 12309
Contact: Steven Weitz   
Northwell Health-Staten Island Recruiting
SI, New York, United States
Contact: Howard Levite   
Stony Brook University Medical Center Recruiting
Stony Brook, New York, United States, 11794
Contact: Luis Gruberg   
United States, North Carolina
Asheville Cardiology Associates Recruiting
Asheville, North Carolina, United States, 28803
Contact: William Abernethy   
Duke University Medical Center Recruiting
Durham, North Carolina, United States, 27710
Contact: Michael Khouri   
United States, North Dakota
Sanford-Fargo Recruiting
Fargo, North Dakota, United States, 58122
Contact: Thomas Haldis   
United States, Ohio
Cincinnati V.A. Medical Center Recruiting
Cincinnati, Ohio, United States
Contact: Imran Arif       ISCHEMIA <>   
Louis Stokes V.A. Medical Center Recruiting
Cleveland, Ohio, United States, 44106
Contact: Jonathan Goldberg   
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: Arnold Good   
United States, Oklahoma
Oklahoma City V.A. Medical Center Recruiting
Oklahoma City, Oklahoma, United States
Contact: Pedro Lozano   
Oklahoma Heart Institute Recruiting
Tulsa, Oklahoma, United States, 74133
Contact: Edward Martin   
United States, Oregon
Oregon Health and Science University Recruiting
Portland, Oregon, United States, 97201
Contact: Michael Shapiro   
Providence Heart and Vascular Institute Recruiting
Portland, Oregon, United States, 97225
Contact: Charles Cannan   
United States, Pennsylvania
Saint Luke's Hospital and Health Network Recruiting
Bethlehem, Pennsylvania, United States, 18018
Contact: Francis Burt   
Holy Spirit Hospital Cardiovascular Institute Recruiting
Camp Hill, Pennsylvania, United States, 17011
Contact: Christopher Spizzieri   
Doylestown Cardiology Associates Recruiting
Doylestown, Pennsylvania, United States, 18901
Contact: Joseph McGarvey   
Conemaugh Valley Memorial Hospital Recruiting
Johnstown, Pennsylvania, United States, 15905
Contact: Robert Stenberg   
Kidney and Hypertension Specialists, PLLC Recruiting
Manassas, Pennsylvania, United States
Contact: Rashida Rahman   
Albert Einstein Medical Center Recruiting
Philadelphia, Pennsylvania, United States
Contact: Janani Rangaswami   
V.A. Pittsburgh Healthcare System Terminated
Pittsburgh, Pennsylvania, United States, 15240
UPMC Heart and Vascular Institute Recruiting
Pittsburgh, Pennsylvania, United States
Contact: Prem Soman   
Lehigh Valley - Buxmont Cardiology Withdrawn
Sellersville, Pennsylvania, United States, 18960
United States, Rhode Island
The Miriam Hospital Recruiting
Providence, Rhode Island, United States, 02906
Contact: Paul Gordon   
Brigham and Women's Cardiovascular Associates at Kent Hospital Recruiting
Warwick, Rhode Island, United States, 02886
Contact: Chester Hedgepeth   
United States, South Carolina
Medical University of South Carolina Withdrawn
Charleston, South Carolina, United States, 29425
United States, Tennessee
Vanderbilt University Medical Center Recruiting
Nashville, Tennessee, United States, 37232
Contact: John McPherson   
Saint Thomas Hospital Recruiting
Nashville, Tennessee, United States, 373203
Contact: Andrew Zurick   
United States, Texas
Texas Heart and Vascular Research Recruiting
Austin, Texas, United States, 78745
Contact: Nima Amjadi   
V.A. North Texas Health Care System Recruiting
Dallas, Texas, United States, 75216
Contact: Subhash Banerjee   
Baylor College of Medicine Recruiting
Houston, Texas, United States, 77030
Contact: Ihab Hamzeh   
The Heart Hospital Baylor Plano Recruiting
Plano, Texas, United States, 75093
Contact: Deepika Gopal   
Baylor Research Institute at Legacy Heart Center Recruiting
Plano, Texas, United States
Contact: Srinivasa Potluri   
Audie Murphy V.A. Recruiting
San Antonio, Texas, United States, 78229
Contact: Robert Chilton   
Wichita Falls Heart Clinic Recruiting
Witchita Falls, Texas, United States
Contact: Sriram Sudarshan       ISCHEMIA <>   
United States, Utah
Salt Lake City V.A. Medical Center Recruiting
Salt Lake City, Utah, United States
Contact: Charles Lui   
United States, Vermont
White River Junction VAMC Recruiting
White River Junction, Vermont, United States
Contact: Anthony Gemignani       ISCHEMIA <>   
United States, Virginia
University of Virginia Health System Withdrawn
Charlottesville, Virginia, United States, 22908
Cardiovascular Associates, Ltd. Terminated
Chesapeake, Virginia, United States, 23320
Valley Health Clinical Research Dept Recruiting
Winchester, Virginia, United States, 22601
Contact: Jason Call   
United States, Washington
University of Washington Medical Center Recruiting
Bellevue, Washington, United States, 98004
Contact: Alec Moorman   
United States, Wisconsin
Gundersen Lutheran Medical Center Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Sampoornima Setty   
Hospital Italiano Regional del Sur Bahia Blanca Recruiting
Bahia Blanca, Buenos Aires, Argentina
Contact: Carlos Alvarez       ISCHEMIA <>   
Fundacion Favaloro Recruiting
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1093AAS
Contact: Julio Figal   
Hospital Privado de Comunidad Withdrawn
Mar del Plata, Buenos Aires, Argentina, 7600
Instituto Medico DAMIC Recruiting
Cordoba, CBA, Argentina, 5009
Contact: Luis Guzman   
Sanatorio Mayo S A Withdrawn
Ciudad de Sante Fe, Santa Fe, Argentina, 3000
Instituto Cardiovascular de Rosario Withdrawn
Rosario, Santa Fe, Argentina, 2000
Clinica Del Prado Recruiting
Cordoba, Argentina, 5000
Contact: Lilia Schiavi   
Clinica Romagosa and Clinica De La Familia Recruiting
Cordoba, Argentina, 5000
Contact: Javier Courtis   
Clínica Privada Vélez Sarsfield Recruiting
Cordoba, Argentina
Contact: Mariano Rubio       ISCHEMIA <>   
Sanatorio Allende Recruiting
Cordoba, Argentina
Contact: Hugo Londero       ISCHEMIA <>   
Instituto Cardiovascular San Luis Recruiting
San Luis, Argentina
Contact: Juan Pablo Albisu   
Australia, New South Wales
John Hunter Hospital Recruiting
New Lambton Heights, New South Wales, Australia
Contact: Suku Thambar   
Australia, South Australia
Flinders Medical Centre Recruiting
Bedford Park, South Australia, Australia, 5042
Contact: Majo Joseph   
Australia, Victoria
Austin Health Recruiting
Heidelberg, Victoria, Australia
Contact: Piyush Srivastava       ISCHEMIA <>   
The Alfred Hospital Withdrawn
Melbourne, Victoria, Australia, 3004
Australia, Western Australia
Royal Perth Hospital Recruiting
Perth, Western Australia, Australia, 6000
Contact: James Rankin   
Princess Alexandra Hospital Recruiting
Woolloongabba, Australia
Contact: Magid Fahim   
LKH Graz West Austria Recruiting
Graz, Stmk, Austria, 8020
Contact: Herwig Schuchlenz   
Medical University Innsbruck Withdrawn
Innsbruck, Tyrol, Austria, A-6020
University of Vienna Allgemeines Krankenhaus Recruiting
Vienna, Wien, Austria, 1090
Contact: Irene Lang   
Wilhelminenhospital of Community Vienna Recruiting
Vienna, Wien, Austria, A-1160
Contact: Kurt Huber   
Universitair Ziekenhuis Antwerpen Recruiting
Edegem, Antwerpen, Belgium
Contact: Christiaan Vrints   
AZ Turnhout Campus-Saint Elisabeth Withdrawn
Turnhout, Antwerpen, Belgium
UZ Leuven/Gasthuisberg University Hospital Recruiting
Leuven, Brabant, Belgium
Contact: Kaatje Goetschalckx   
Fundacao Bahiana de Cardilogia Recruiting
Salvador, Bahia, Brazil
Contact: Alvaro Rabelo Alves Junior       ISCHEMIA <>   
Hospital Lifecenter Recruiting
Belo Horizonte, Minas Gerais, Brazil
Contact: Estevao Figueiredo   
Hospital Maternidade e Pronto Socorro Santa Lucia Recruiting
Pocos de Caldas, Minas Gerais, Brazil
Contact: Frederico Dall'Orto   
Hospital Cardiologica Costantini Recruiting
Curitiba, Parana, Brazil
Contact: Costantino Costantini   
Quanta Diagnostico e Terapia Recruiting
Curitiba, Parana, Brazil
Contact: Joao Vitola   
Hospital Pró-Cardíaco Recruiting
Botafogo, Rio de Janeiro, Brazil
Contact: Claudo Mesquita       ISCHEMIA <>   
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sol Recruiting
Porto Alegre, Rio Grande do Sul, Brazil
Contact: Paulo Ricardo Caramori       ISCHEMIA <>   
Instituto de Cardiologia de Porto Alegre Recruiting
Porto Alegre, Rio Grande do Sul, Brazil
Contact: Alexandre de Quadros   
Hospital Sao Vicente de Paulo Recruiting
Fundo, RS, Brazil
Contact: Rogerio Tumelero   
Hospital de Clinicas de Porto Alegre Recruiting
Porto Alegre, RS, Brazil
Contact: Carisi Polanczyk       ISCHEMIA <>   
Itajai Institute Of Research and Medical Studies (IPEMI) Recruiting
Itajai, Santa Catarina, Brazil
Contact: Felipe Baldissera       ISCHEMIA <>   
Instituto Dante Pazzanese de Cardiologia Recruiting
Ibirapuera, Sao Paulo, Brazil
Contact: Paola Smanio       ISCHEMIA <>   
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo Recruiting
Ribeirao Preto, Sao Paulo, Brazil
Contact: Jose Marin-Neto   
Hospital Totalcor Recruiting
Sao Paulo, SP, Brazil
Contact: Expedito Ribeiro da Silva       ISCHEMIA <>   
Instituto Nacional de Cardiologia Laranjeiras Withdrawn
Rio de Janeiro, Brazil
Hospital Da Bahia Recruiting
Salvador, Brazil
Contact: Marianna Andrade   
Heart Instituto do Coracao - University of Sao Paulo Recruiting
Sao Paulo, Brazil
Contact: Whady Hueb       ISCHEMIA <>   
Hospital Celso Pierro Recruiting
Sao Paulo, Brazil
Contact: Jose Francisco Saraiva       ISCHEMIA <>   
University Federal Hospital of Sao Paulo Recruiting
Sao Paulo, Brazil
Contact: Antonio Carlos Carvalho       ISCHEMIA <>   
Hucam Ufes Recruiting
Vitoria, Brazil
Contact: Werther Clay M. Rosa   
Canada, Alberta
University of Alberta Hospital Recruiting
Edmonton, Alberta, Canada
Contact: Kevin Bainey   
Canada, British Columbia
Saint Paul's Hospital Terminated
Vancouver, British Columbia, Canada
Vancouver General Hospital Recruiting
Vancouver, British Columbia, Canada
Contact: Graham Wong   
Canada, Ontario
West Lincoln Memorial Hospital Recruiting
Grimsby, Ontario, Canada
Contact: Andy Lam   
Hamilton General Hospital Recruiting
Hamilton, Ontario, Canada
Contact: Shamir Mehta   
University Hospital Recruiting
London, Ontario, Canada
Contact: Dennis Humen   
Dixie Medical Group Recruiting
Mississauga, Ontario, Canada
Contact: Asim Cheema   
Dr. James Cha (Private Practice affiliated Lakeridge Helath of Oshawa) Recruiting
Oshawa, Ontario, Canada
Contact: James Cha   
University of Ottawa Heart Institute Recruiting
Ottawa, Ontario, Canada
Contact: Renee Hessian   
Scarborough Cardiology Research Recruiting
Scarborough, Ontario, Canada
Contact: Paul Galiwango   
Saint Catharines General Hospital Recruiting
St. Catharines, Ontario, Canada
Contact: Adnan Hameed       ISCHEMIA <>   
Mount Sinai Hospital Recruiting
Toronto, Ontario, Canada
Contact: John Parker   
Saint Michael's Hospital Recruiting
Toronto, Ontario, Canada
Contact: Asim Cheema   
University Health Network Recruiting
Toronto, Ontario, Canada
Contact: Amar Uxa   
Women's College Hospital Recruiting
Toronto, Ontario, Canada
Contact: Jacob Udell   
Northwest GTA Cardiovascular & Heart Rhythm Program Recruiting
Vaughan, Ontario, Canada
Contact: Ledjalem Daba         
Canada, Quebec
Montreal Heart Institute Recruiting
Montreal, Quebec, Canada
Contact: Gilbert Gosselin   
Höpital du Sacré-Coeur de Montréal Recruiting
Montréal, Quebec, Canada
Contact: Philippe Généreux       ISCHEMIA <>   
CSSS du Sud de Lanaudiere Recruiting
Terrebonne, Quebec, Canada
Contact: Denis Phaneuf   
Centre Hospitalier de Regional Trois-Rivieres Recruiting
Trois-Rivieres, Quebec, Canada
Contact: Ariel Diaz   
MUHC McGill University Health Center Recruiting
Montreal, Canada
Contact: James (Jay) Brophy   
Quebec Heart and Lung Institute Withdrawn
Quebec, Canada
China, Beijing
Beijing Chao-yang Hospital, Capital Medical University Recruiting
Beijing, Beijing, China
Contact: Xinchun Yang   
Fuwai Hospital Recruiting
Beijing, Beijing, China
Contact: Hongbing Yan   
China, Guangdong
Guangdong General Hospital Recruiting
Guangzhou, Guangdong, China
Contact: Jiyan Chen   
China, Henan
The First Affiliated Hospital of Zhengzhou University Recruiting
Zhengzhou, Henan, China
Contact: Xin Fu   
China, Hubei
Tongji Medical College Recruiting
Wuhan, Hubei, China
Contact: Hesong Zeng       ISCHEMIA <>   
Wuhan Asia Heart Hospital Recruiting
Wuhan, Hubei, China
Contact: Xi Su   
Wuhan Union Hospital, Tongji Medical College, Huazhong Science and Tech University Recruiting
Wuhan, Hubei, China
Contact: Qiutang Zeng   
China, Shandong
Affiliated Hospital of Jining Medical University Recruiting
Jining, Shandong, China
Contact: Qingxian Li   
Qingdao Fuwai Hospital Recruiting
Qingdao, Shandong, China
Contact: Ying Yang   
China, Shanxi
Shanxi Cardiovascular Hospital Recruiting
Taiyuan, Shanxi, China
Contact: Bao Li   
China, Xinjiang
First Affiliated Hospital of Xinjiang Medical University Recruiting
Urumqi, Xinjiang, China
Contact: Yining Yang       ISCHEMIA <>   
Beijing Anzhen Hospital Recruiting
Beijing, China
Contact: Shao-ping Nie   
Peking Union Medical College Hospital Recruiting
Beijing, China
Contact: Shuyang Zhang   
The Second Affiliated Hospital Zhejiang University School of Medicine Recruiting
Hangzhou, China
Contact: Jian'an Wang   
TEDA International Cardiovascular Hospital Recruiting
Tianjing, China
Contact: Wenhua Lin   
Cairo University Faculty of Medicine Recruiting
Cairo, Egypt
Contact: Magdy Hamid   
C.H. Louis Pasteur Recruiting
Chatres, Centre, France
Contact: Christophe Thuaire   
Ambroise Pare Hospital Recruiting
Boulogne, Ile De France, France
Contact: Rami El Mahmoud       ISCHEMIA <>   
Centre Hospitalier Sud Francilien Recruiting
Corbeil-Essonnes cedex, Ile de France, France
Contact: Eric Nicollet   
Bichat Hospital Recruiting
Paris, Ile-de-France, France
Contact: Philippe-Gabriel Steg   
Grenoble University Hospital Recruiting
Grenoble, Isere, France
Contact: Gilles Barone-Rochette   
Robert Bosch Hospital Recruiting
Stuttgart, BW, Germany
Contact: Udo Sechtem       ISCHEMIA <>   
University of Ulm Withdrawn
Ulm, BW, Germany
Universitatsklinikum Bonn Recruiting
Bonn, NRW, Germany
Contact: Georg Nickenig   
Universitaetsklinikum Duesseldorf Withdrawn
Dusseldorf, NRW, Germany
Praxisklinik Herz Und Gefaesse Recruiting
Dresden, Saxony, Germany
Contact: Rolf Doerr   
University of Pecs, Heart Institute Terminated
Pecs, Baranya, Hungary
University of Szeged Recruiting
Szeged, Szeged Megyei Varos, Hungary
Contact: Albert Varga   
George Gottsegen National Institute of Cardiology Recruiting
Budapest, Hungary
Contact: Geza Fontos   
Semmelweis University Recruiting
Budapest, Hungary
Contact: Bela Merkely   
Szent Istvan Hospital Recruiting
Budapest, Hungary
Contact: Andras Vertes   
Gurunanak CARE Hospital Recruiting
Hyderabad, AP, India
Contact: Johann Christopher   
Fortis Escorts Heart Institute Recruiting
New Delhi, Delhi, India
Contact: Upendra Kaul       ISCHEMIA <>   
Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore-Karnataka Recruiting
Bangalore, Karnataka, India
Contact: Cholenahally Manjunath   
Medical College Calicut Recruiting
Calicut, Kerala, India
Contact: Mangalath Krishnan   
Amrita Institute of Medical Sciences and Research Centre Withdrawn
Eanakulam, Kerala, India
MOSC Medical College Hospital, Kolenchery Recruiting
Kolenchery, Kerala, India
Contact: Anoop Mathew   
Sree Chitra Tirunal Institute for Medical Sciences and Technology Recruiting
Trivandrum, Kerala, India
Contact: Jaganmohan Tharakan       ISCHEMIA <>   
KEM Hospital Recruiting
Pune, Maharashtra, India
Contact: Milind Gadkari   
Hero DMC Heart Institute Unit Dayanand Medical Recruiting
Ludhiana, Punjab, India
Contact: Gurpreet Wander   
Apollo Hospitals Recruiting
Chennai, Tamil Nadu, India
Contact: Robert Mao       ISCHEMIA <>   
Frontier Lifeline Hospital Withdrawn
Chennai, Tamilnadu, India
Madras Medical Mission Withdrawn
Chennai, Tamilnadu, India
Apollo Health City Campus Recruiting
Hyderabad, Telangana, India
Contact: Sudhir Naik       ISCHEMIA <>   
CARE Hospital Recruiting
Hyderabad, Telangana, India
Contact: Johann Christopher   
King George Medical University Recruiting
Lucknow, Uttar Pradesh, India
Contact: Sudhanshu Dwivedi   
Ram Manohar Lohia Hospital Recruiting
Delhi, India
Contact: Neeraj Pandit   
Sir Gangaram Hospital Recruiting
Delhi, India
Contact: Rajneesh Jain   
All India Institute of Medical Sciences Recruiting
New Delhi, India, 110029
Contact: Balram Bhargava   
Fortis Healthcare Fl.t Lt. Rajan Dhall Hospital Recruiting
New Delhi, India
Contact: Upendra Kaul   
Jawaharlal Institute of Postgraduate Medical Education and Research Recruiting
Pondicherry, India
Contact: Santhosh Satheesh       ISCHEMIA <>   
Ruby Hall Clinic Recruiting
Pune, India
Contact: Purvez Grant   
Rambam Medical Center Recruiting
Haifa, Israel
Contact: Arthur Kerner   
Assuta Medical Centers Recruiting
Tel-Aviv, Israel
Contact: Tali Sharir   
Policlinico San Marco Recruiting
Osio Sotto, Bergamo, Italy
Contact: Alvise Polese   
Second University of Naples - Monaldi Hospital Recruiting
Napoli, Campania, Italy
Contact: Paolo Calabra   
GB Morgagni Hospital-Forli Recruiting
Forli, Emilia-Romagna, Italy
Contact: Marcello Galvani   
UOC Cardiologia Ospedale Santo Spirito Roma Terminated
Rome, Lazio, Italy
Ospedali Riuniti of Ancona Recruiting
Ancona, Marche, Italy
Contact: Gian Perna   
Policlinico di Monza Recruiting
Monza, MB, Italy
Contact: Andrea Mortara   
Istituto Clinico Humanitas Recruiting
Rozzano, Milano, Italy
Contact: Lorenzo Monti   
Azienda Ospedaliera S. Croce e Carle Recruiting
Cuneo, Piemonte, Italy
Contact: Emanuela Racca   
UO Cardiologia Ospedale SS Cosma e Damiano Recruiting
Pescia, Pistoia, Italy
Contact: William Vergoni   
Cardiocentro Ticino Recruiting
Lugano, Ticino, Italy
Contact: Tiziano Moccetti   
Ospedale Civile S. Antonio Abate Recruiting
Tolmezzo, Udine, Italy
Contact: Antonia di Chiara   
University of Padua Recruiting
Padua, Veneto, Italy
Contact: Giuseppe Tarantini   
Ospedale Regionale Umberto Parini Recruiting
Aosta, Italy
Contact: Marco Sicuro   
Policlinico San Marco Recruiting
Bergamo, Italy
Contact: Alvise Polese   
OORR Foggia Withdrawn
Foggia, Italy
Ospedale S. Camillo Withdrawn
Rome, Italy
Ospedale di Circolo e Fondazione Macchi Recruiting
Varese, Italy
Contact: Edoardo Verna   
National Cerebral and Cardiovascular Center Recruiting
Suita-shi, Osaka, Japan
Contact: Satoshi Yasuda   
Saitama Medical University Recruiting
Hidaka, Saitama, Japan
Contact: Shigeyuki Nishimura   
Keio University Hospital Recruiting
Shinjuka, Tokyo, Japan
Contact: Keiichi Fukuda   
Vilnius University Hospital Santariskes Clinic Recruiting
Vilnius, Lithuania
Contact: Aleksandras Laucevicius   
IMSS Recruiting
Benito Juarez, DF, Mexico
Contact: Jorge Escobedo   
Instituto Nacional de Cardiologia Ignacio Chavez Recruiting
Mexico City, Distrito Federal, Mexico
Contact: Erick Alexanderson-Rosas       ISCHEMIA <>   
Hospital Central Dr. Ignacio Morones Prieto Recruiting
SLP, Mexico
Contact: Juan-Manuel Lopez-Quijano   
Cardio Research Hartcentrum OLVG Recruiting
Amsterdam, NH, Netherlands
Contact: Robert Riezebos       ISCHEMIA <>   
Radboud University Medical Center Recruiting
Nijmegen, Netherlands
Contact: Harry Suryapranata   
Isala Klinieken Weezenlanden Recruiting
Zwolle, Netherlands
Contact: Jorik Timmer   
New Zealand
Waikato Hospital Recruiting
Hamilton, Waikato, New Zealand
Contact: Gerard Devlin   
Auckland City Hospital Recruiting
Auckland, New Zealand
Contact: Ralph Stewart       ISCHEMIA <>   
Instituto Neuro Cardiovascular de las Americas Recruiting
Mirafloes, Lima, Peru
Contact: Walter Mogrovejo Ramos       ISCHEMIA <>   
Polyclinic Independent Public Health Department, 4th Military Clinical Hospital Recruiting
Wroclaw, Dolny Slask, Poland
Contact: Krysztof Reczuch   
Lower Silesia Specialist Hospital T Marciniak Recruiting
Wrocław, Dolny Śląsk, Poland
Contact: Krystyna Loboz-Grudzien   
Medical University of Lodz Recruiting
Lodz, Lodzkie, Poland
Contact: Jarozlaw Drozdz   
John Paul II Hospital Recruiting
Krakow, Maopolskie, Poland
Contact: Grzegorz Gajos   
2 nd Department of Coronary Artery Disease Recruiting
Warsaw, Mazovian, Poland
Contact: Hanna Szwed   
2 nd Department of Coronary Artery Disease Recruiting
Warsaw, Mazowieckie, Poland
Contact: Adam Witkowski   
Coronary and Structural Heart Diseases Department, Institute of Cardiology, Warsaw Recruiting
Warsaw, Mazowieckie, Poland
Contact: Marcin Demkow   
Independent Public Central Clinical Hospital, Medical University of Warsaw Recruiting
Warsaw, Mazowieckie, Poland
Contact: Tomasz Mazurek   
Department of Internal Medicine, Infant Jesus Teaching Hospital, Medical University of Warsaw Recruiting
Warszawa, Mazowieckie, Poland
Contact: Piotr Pruszczyk   
University Hospital in Bialystok Recruiting
Bialystok, Podlaskie, Poland
Contact: Wlodzimierz Musial   
Silesian Center for Heart Diseases Recruiting
Zabrze, Wojewodztwo Slaskie, Poland
Contact: Zbigniew Kalarus   
Silesian Center for Heart Disease Terminated
Zabrze, Wojewodztwo Slaskie, Poland
Bieganski Hospital Medical University of Lodz Withdrawn
Lodz, Poland
University Hospital of the Lord's Transfiguration Recruiting
Poznan, Poland
Contact: Maciej Lesiak   
John Paul II Hospital Recruiting
Zamosc, Poland
Contact: Andrzej Kleinrok   
Hospital Fernando Fonseca Recruiting
Amadora, Lisboa, Portugal
Contact: Pedro Abreu       ISCHEMIA <>   
Hospital de Santa Marta Recruiting
Lisboa, Portugal
Contact: Ruben Ramos   
CHLN - Hospital Santa Maria Recruiting
Lisbon, Portugal
Contact: Fausto Pinto   
Mures Emergency County Hospital, Center of Cardiovascular Diseases, Cardiac Catheterization Laborato Withdrawn
Targu Mures, Mures, Romania
County Emergency Hospital Baia Mare Recruiting
Baia Mare, Romania
Contact: Calin Pop   
Russian Federation
Bakulev Scientific Center for Cardiovascular Surgery Recruiting
Moscow, Gorod Moskva, Russian Federation
Contact: Leo Bockeria   
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology Recruiting
Novosibirsk, Novosibirskaya Oblast, Russian Federation
Contact: Alexander Chernyavskiy   
North West State Medical University n.a.I.I. Mechnikov Recruiting
Saint Petersburg, Russian Federation
Contact: Leonid Bershtein   
Almnazov Federal - Heart Blood and Endocrinology Centre Recruiting
Saint-Petersburg, Russian Federation
Contact: Elena Demchenko   
Saudi Arabia
King Abdul Aziz Cardiac Center Recruiting
Riyadh, Central Province, Saudi Arabia
Contact: Mouaz Al-Mallah   
Dedinje Cardiovascular Institute Withdrawn
Belgrade, Savski Venac, Serbia
Institute of Cardiovascular Diseases, Vojvodina - Sremska Kamenica Recruiting
Sremska Kamenica, Vojvodina, Serbia
Contact: Nada Cemerlic Adjic   
Cardiology Clinic at Clinical Center of Serbia Recruiting
Belgrade, Serbia
Contact: Branko Beleslin   
Cardiovascular Institute Dedinje, Belgrade, Serbia Recruiting
Belgrade, Serbia
Contact: Ljiljana Jovovic   
Clinical Center of Serbia Recruiting
Belgrade, Serbia
Contact: Petar Seferovic   
University Clinical Hospital Zvezdara Recruiting
Belgrade, Serbia
Contact: Milica Dekleva   
University Hospital Center Bezanijska Kosa Recruiting
Belgrade, Serbia
Contact: Sasa Hinic   
Clinical Center Kragujevac Recruiting
Kragujevac, Serbia
Contact: Goran Davidovic   
Clinic for cardiovascular diseases, Clinical Center Nis Recruiting
Nis, Serbia
Contact: Svetlana Apostolovic   
National Heart Centre Singapore Recruiting
Singapore, Singapore
Contact: Terrance Chua   
National University Heart Center Recruiting
Singapore, Singapore
Contact: Kian Keong Poh   
Tan Tock Seng Hospital Recruiting
Singapore, Singapore
Contact: David Foo   
Hospital Universitario Puerta de Hierro de Majadahonda Withdrawn
Majadahonda, Madrid, Spain
Complejo Hospitalario Universitario de A Coruna Recruiting
A Coruna, Spain
Contact: Jesus Peteiro   
Hospital de Bellvitge Recruiting
Barcelona, Spain
Contact: Guillermo Sanchez-Elvira   
Hospital de Sant Pau Barcelona Recruiting
Barcelona, Spain
Contact: Alessandro Sionis   
Hospital General Universitario Gregorio Maranon Recruiting
Madrid, Spain
Contact: Francisco Fernandez-Aviles   
Hospital Universitario La Paz Recruiting
Madrid, Spain
Contact: Jose Luis Lopez Sendon   
Hospital Virgen de la Arrixaca Recruiting
Murcia, Spain
Contact: Francisco Marin   
Hospital Clinico de Santiago de Compostela Recruiting
Santiago de Compostela, Spain
Contact: Emad Abu-Assi       ISCHEMIA <>   
Hospital Universitario y Politecnico La Fe Recruiting
Valencia, Spain
Contact: Vicente Miro   
Danderyds Hospital Recruiting
Stockholm, Sweden
Contact: Johannes Aspberg   
Uppsala University Recruiting
Uppsala, Sweden
Contact: Claes Held   
Mackay Memorial Hospital Recruiting
Taipei City, Taiwan
Contact: Chung-Lieh Hung   
Ramathibodi Hospital Recruiting
Rajthevi, Bangkok, Thailand
Contact: Piyamitr Sritara   
Chiang Mai University Hospital Recruiting
Chiang Mai, Meung, Thailand
Contact: Srun Kuanprasert   
United Arab Emirates
SKMC - Sheikh Khalifa Medical City. Recruiting
Abu Dhabi, United Arab Emirates
Contact: Wael Almahmeed   
United Kingdom
The Belfast Health and Social Care Trust Recruiting
Belfast, Antrim, United Kingdom
Contact: Nicola Johnston   
Bedford Hospital NHS Trust Recruiting
Bedford, Bedfordshire, United Kingdom
Contact: Ramesh de Silva   
Luton and Dunstable Hospital Recruiting
Luton, Berdfordshire, United Kingdom
Contact: Christopher Travill   
Papworth Hospital NHS Foundation Trust Recruiting
Cambridge, Cambridgeshire, United Kingdom
Contact: Stephen Hoole   
Peterborough City Hospital Recruiting
Peterborough, Cambs, United Kingdom
Contact: Denise Braganza   
The James Cook University Hospital Recruiting
Middlesbrough, Cleveland, United Kingdom
Contact: Mark de Belder   
Royal Bournemouth Hospital Recruiting
Bournemouth, Dorset, United Kingdom
Contact: Peter Okane   
Dorset County Hospital Recruiting
Dorchester, Dorset, United Kingdom
Contact: Fraser Witherow   
The University of Hull/Castle Hill Hospital Recruiting
Cottingham, East Yorkshire, United Kingdom
Contact: Angela Hoye   
Basildon and Thurrock Hospitals NHS Foundation Trust Withdrawn
Basildon, Essex, United Kingdom
Broomfield Hospital NHS Trust Recruiting
Chelmsford, Essex, United Kingdom
Contact: Reto Gamma   
Southend University Hospital NHS Trust Recruiting
Westcliffe on Sea, Essex, United Kingdom
Contact: Thuraia Nageh       ISCHEMIA <>   
Central Manchester University Hospital Recruiting
Manchester, Lancashire, United Kingdom
Contact: Helen Dormand   
Royal Oldham Hospital Recruiting
Oldham, Lancashire, United Kingdom
Contact: Jolanta Sobolewska   
Blackpool Teaching Hospitals Recruiting
Blackpool, Lancs, United Kingdom
Contact: Anoop Chauhan   
Northwick Park Hospital-Royal Brompton Hospital, London Recruiting
Harrow, Middlesex, United Kingdom
Contact: Roxy Senior   
Ulster Hospital Recruiting
Belfast, Northern Ireland, United Kingdom
Contact: Patrick Donnelly   
Craigavon Area Hospital Recruiting
Craigavon, Northern Ireland, United Kingdom
Contact: Andrew Moriarty         
Nottingham University Hospitals Recruiting
Nottingham, Notts, United Kingdom
Contact: Robert Henderson   
South Glasgow Hospitals Recruiting
Clydebank, Strathclyde, United Kingdom
Contact: Colin Berry   
University Hospital of Wales - Cardiff Withdrawn
Cardiff, Wales, United Kingdom
Bradford Royal Infirmary Recruiting
Bradford, United Kingdom
Contact: Steven Lindsay   
Edinburgh Heart Centre Recruiting
Edinburgh, United Kingdom
Contact: Peter Henriksen   
Barts Health NHS Trust Recruiting
London, United Kingdom
Contact: Alex Sirker   
Imperial College Healthcare NHS Trust Recruiting
London, United Kingdom
Contact: Mikhail Ghada   
King's College Hospital Recruiting
London, United Kingdom
Contact: Alfakih Khaled   
University College London Hospital Terminated
London, United Kingdom
Pinderfields General Hospital Recruiting
Wakefield, United Kingdom
Contact: Dwayne Conway   
Sponsors and Collaborators
New York University School of Medicine
New York University
Stanford University
National Heart, Lung, and Blood Institute (NHLBI)
Albany Stratton VA Medical Center
Cedars-Sinai Medical Center
Columbia University
Duke University
East Carolina University
Emory University
Harvard University
Massachusetts General Hospital
Montreal Heart Institute
University of British Columbia
University of Missouri, Kansas City
Vanderbilt University
Study Chair: Judith S Hochman, MD New York University
Principal Investigator: David J Maron, MD Stanford University
  More Information

Additional Information:
Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: New York University School of Medicine Identifier: NCT01471522     History of Changes
Obsolete Identifiers: NCT02347215
Other Study ID Numbers: 11-00498  1U01HL105907 
Study First Received: November 10, 2011
Last Updated: October 13, 2016
Health Authority: United States: Data and Safety Monitoring Board
United States: Institutional Review Board
United States: Federal Government

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Arterial Occlusive Diseases
Vascular Diseases
Pathologic Processes processed this record on October 21, 2016