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Can Hospital Acquired Pneumonia be Prevented in Patients Who Gurgle?

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ClinicalTrials.gov Identifier: NCT01134133
Recruitment Status : Withdrawn (Slow recruitment (preemptive treatment of gurglers, after association was published))
First Posted : May 31, 2010
Last Update Posted : June 23, 2011
Sponsor:
Information provided by:
Bridgeport Hospital

Study Description
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Brief Summary:
Hospital inpatients who have gurgling sounds heard during speech or breathing have been observed to have a higher risk of hospital acquired pneumonia. Patients who gurgle and who consent to participation will be randomized to receive routine clinical management or management to include measures employed to reduce risks of aspiration, namely, 1. head of bed up (30 degrees or higher), 2. swallowing evaluation by speech therapist (and feeding predicated on formal evaluation), 3. prompting managing physicians to reduce sedating medications to minimal effective dose.

Condition or disease Intervention/treatment Phase
Hospital Acquired Pneumonia in Gurgling Patients Other: Anti-gurgling intervention Phase 1 Phase 2

Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 50 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Can Hospital Acquired Pneumonia be Prevented in Patients Who Gurgle?
Study Start Date : February 2010
Actual Primary Completion Date : July 2010
Actual Study Completion Date : July 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pneumonia

Arms and Interventions
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Intervention Details:
  • Other: Anti-gurgling intervention
    1. head of bed 30 degrees or higher, 2. swallowing evaluation-based feeding, 3. sedatives titrated to minimal effective dose.

Outcome Measures
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Primary Outcome Measures :
  1. Hospital acquired pneumonia [ Time Frame: 14 days (average) ]

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Gurglers who consent to participate

Exclusion Criteria:

  • Non-gurglers
  • Patients presenting with pneumonia prior to identification with gurgling
  • Patients receiving comfort-care-only
Contacts and Locations
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No Contacts or Locations Provided
More Information
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Responsible Party: Constantine A. Manthous, MD, Bridgeport Hospital
ClinicalTrials.gov Identifier: NCT01134133    
Other Study ID Numbers: Gurgle
First Posted: May 31, 2010    Key Record Dates
Last Update Posted: June 23, 2011
Last Verified: February 2010
Additional relevant MeSH terms:
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Pneumonia
Healthcare-Associated Pneumonia
Respiratory Tract Infections
Infections
Lung Diseases
 Respiratory Tract Diseases
Cross Infection
Iatrogenic Disease
Disease Attributes
Pathologic Processes