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Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease-

This study has been completed.
Information provided by (Responsible Party):
Eisai Inc. ( Eisai Co., Ltd. ) Identifier:
First received: May 21, 2010
Last updated: February 23, 2017
Last verified: January 2017
The purpose of this study is to investigate the following about donepezil hydrochloride administration in patients with mild or moderate Alzheimer's Disease in clinical practice: cognitive function, Functional Assessment Staging (FAST) score, adverse events/adverse drug reactions, and patient background.

Condition Intervention
Alzheimer's Disease
Drug: donepezil hydrochloride

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease-

Resource links provided by NLM:

Further study details as provided by Eisai Inc.:

Primary Outcome Measures:
  • The transition of clinical condition is evaluated comparing the result of HDS-R,MMSE with the time of study initiation [ Time Frame: 48 months(12 weeks and every 6 months) ]

Enrollment: 10238
Actual Study Start Date: June 10, 2010
Study Completion Date: April 1, 2016
Primary Completion Date: September 25, 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1 Drug: donepezil hydrochloride
This is a multicenter, open-labeled, practice-based, post-marketing surveillance study. Therefore, dosing is not specified.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Hospital, Clinical. Japan

Inclusion criteria:

Patients diagnosed with Alzheimer's Disease by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). Patients diagnosed with mild or moderate Alzheimer's Disease, applicable to FAST score 4 or 5.

Exclusion criteria:

Patients with history of hypersensitivity to component of Aricept or piperidine derivative. Patients registered for this survey before.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01129596

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Aisai, Aichi, Japan
Chita, Aichi, Japan
Gamagori, Aichi, Japan
Handa, Aichi, Japan
Ichinomiya, Aichi, Japan
Inazawa, Aichi, Japan
Inuyama, Aichi, Japan
Kariya, Aichi, Japan
Kasugai, Aichi, Japan
Komaki, Aichi, Japan
Konan, Aichi, Japan
Nagoya, Aichi, Japan
Nishio, Aichi, Japan
Nisshin, Aichi, Japan
Obu, Aichi, Japan
Okazaki, Aichi, Japan
Owariasahi, Aichi, Japan
Seto, Aichi, Japan
Shinshiro, Aichi, Japan
Tahara, Aichi, Japan
Tokai, Aichi, Japan
Tokoname, Aichi, Japan
Toyoake, Aichi, Japan
Toyohashi, Aichi, Japan
Toyokawa, Aichi, Japan
Toyota, Aichi, Japan
Yatomi, Aichi, Japan
Daisen, Akita, Japan
Katagami, Akita, Japan
Odate, Akita, Japan
Oga, Akita, Japan
Semboku, Akita, Japan
Yokote, Akita, Japan
Yurihonjo, Akita, Japan
Yuzawa, Akita, Japan
Goshogawara, Aomori, Japan
Hachinohe, Aomori, Japan
Hirosaki, Aomori, Japan
Kamikita, Aomori, Japan
Kitatsugaru, Aomori, Japan
Mutsu, Aomori, Japan
Sannohe, Aomori, Japan
Towada, Aomori, Japan
Abiko, Chiba, Japan
Asahi, Chiba, Japan
Choshi, Chiba, Japan
Funabashi, Chiba, Japan
Ichihara, Chiba, Japan
Ichikawa, Chiba, Japan
Inzai, Chiba, Japan
Isumi, Chiba, Japan
Kashiwa, Chiba, Japan
Katori, Chiba, Japan
Kimitsu, Chiba, Japan
Kisarazu, Chiba, Japan
Matsudo, Chiba, Japan
Mobara, Chiba, Japan
Nagareyama, Chiba, Japan
Narita, Chiba, Japan
Sakura, Chiba, Japan
Sambu, Chiba, Japan
Sammu, Chiba, Japan
Tateyama, Chiba, Japan
Togane, Chiba, Japan
Yachimata, Chiba, Japan
Yachiyo, Chiba, Japan
Yotsukaido, Chiba, Japan
Imabari, Ehime, Japan
Iyo, Ehime, Japan
Kamiukena, Ehime, Japan
Matsuyama, Ehime, Japan
Minamiuwa, Ehime, Japan
Niihama, Ehime, Japan
Ozu, Ehime, Japan
Saijo, Ehime, Japan
Seiyo, Ehime, Japan
Shikokuchuo, Ehime, Japan
Toon, Ehime, Japan
Uwajima, Ehime, Japan
Yawatahama, Ehime, Japan
Echizen, Fukui, Japan
Katsuyama, Fukui, Japan
Mikatakaminaka, Fukui, Japan
Obama, Fukui, Japan
Sabae, Fukui, Japan
Sakai, Fukui, Japan
Tsuruga, Fukui, Japan
Asakura, Fukuoka, Japan
Chikugo, Fukuoka, Japan
Chikushino, Fukuoka, Japan
Chikushi, Fukuoka, Japan
Fukutsu, Fukuoka, Japan
Iizuka, Fukuoka, Japan
Itoshima, Fukuoka, Japan
Kasuga, Fukuoka, Japan
Kasuya, Fukuoka, Japan
Kitakyushu, Fukuoka, Japan
Kurume, Fukuoka, Japan
Miyako, Fukuoka, Japan
Miyama, Fukuoka, Japan
Nakama, Fukuoka, Japan
Nogata, Fukuoka, Japan
Ogori, Fukuoka, Japan
Omuta, Fukuoka, Japan
Onga, Fukuoka, Japan
Onojo, Fukuoka, Japan
Tagawa, Fukuoka, Japan
Ukiha, Fukuoka, Japan
Yanagawa, Fukuoka, Japan
Yukuhashi, Fukuoka, Japan
Aizuwakamatsu, Fukushima, Japan
Date, Fukushima, Japan
Futaba, Fukushima, Japan
Higashishirakawa, Fukushima, Japan
Ishikawa, Fukushima, Japan
Iwaki, Fukushima, Japan
Kitakata, Fukushima, Japan
Koriyama, Fukushima, Japan
Nihonmatsu, Fukushima, Japan
Onuma, Fukushima, Japan
Soma, Fukushima, Japan
Sukagawa, Fukushima, Japan
Tamura, Fukushima, Japan
Yama, Fukushima, Japan
Ena, Gifu, Japan
Gujo, Gifu, Japan
Hashima, Gifu, Japan
Minokamo, Gifu, Japan
Mizuho, Gifu, Japan
Nakatsugawa, Gifu, Japan
Ogaki, Gifu, Japan
Seki, Gifu, Japan
Tajimi, Gifu, Japan
Takayama, Gifu, Japan
Toki, Gifu, Japan
Yamagata, Gifu, Japan
Fujioka, Gumma, Japan
Isesaki, Gumma, Japan
Kiryu, Gumma, Japan
Kitagumma, Gumma, Japan
Maebashi, Gumma, Japan
Numata, Gumma, Japan
Ora, Gumma, Japan
Ota, Gumma, Japan
Shibukawa, Gumma, Japan
Takasaki, Gumma, Japan
Tatebayashi, Gumma, Japan
Tomioka, Gumma, Japan
Tone, Gumma, Japan
Aki, Hiroshima, Japan
Fuchu, Hiroshima, Japan
Fukuyama, Hiroshima, Japan
Higashihiroshima, Hiroshima, Japan
Kure, Hiroshima, Japan
Mihara, Hiroshima, Japan
Miyoshi, Hiroshima, Japan
Onomichi, Hiroshima, Japan
Otake, Hiroshima, Japan
Shobara, Hiroshima, Japan
Takehara, Hiroshima, Japan
Abashiri, Hokkaido, Japan
Akkeshi, Hokkaido, Japan
Asahikawa, Hokkaido, Japan
Ashibetsu, Hokkaido, Japan
Bibai, Hokkaido, Japan
Chitose, Hokkaido, Japan
Date, Hokkaido, Japan
Ebetsu, Hokkaido, Japan
Eniwa, Hokkaido, Japan
Fukagawa, Hokkaido, Japan
Furano, Hokkaido, Japan
Hakodate, Hokkaido, Japan
Hiroo, Hokkaido, Japan
Hokuto, Hokkaido, Japan
Ishikari, Hokkaido, Japan
Iwamizawa, Hokkaido, Japan
Kameda, Hokkaido, Japan
Kamikawa, Hokkaido, Japan
Kato, Hokkaido, Japan
Kawakami, Hokkaido, Japan
Kitami, Hokkaido, Japan
Kushiro, Hokkaido, Japan
Mombetsu, Hokkaido, Japan
Muroran, Hokkaido, Japan
Nakagawa, Hokkaido, Japan
Nayoro, Hokkaido, Japan
Noboribetsu, Hokkaido, Japan
Obihiro, Hokkaido, Japan
Otaru, Hokkaido, Japan
Rumoi, Hokkaido, Japan
Sapporo, Hokkaido, Japan
Shibetsu, Hokkaido, Japan
Sorachi, Hokkaido, Japan
Soya, Hokkaido, Japan
Sunagawa, Hokkaido, Japan
Tomakomai, Hokkaido, Japan
Yoichi, Hokkaido, Japan
Yufutsu, Hokkaido, Japan
Akashi, Hyogo, Japan
Ako, Hyogo, Japan
Amagasaki, Hyogo, Japan
Asago, Hyogo, Japan
Ashiya, Hyogo, Japan
Awaji, Hyogo, Japan
Himeji, Hyogo, Japan
Itami, Hyogo, Japan
Kakogawa, Hyogo, Japan
Kako, Hyogo, Japan
Kasai, Hyogo, Japan
Kato, Hyogo, Japan
Kawabe, Hyogo, Japan
Kawanishi, Hyogo, Japan
Kobe, Hyogo, Japan
Miki, Hyogo, Japan
Nishinomiya, Hyogo, Japan
Sanda, Hyogo, Japan
Shiso, Hyogo, Japan
Sumoto, Hyogo, Japan
Takarazuka, Hyogo, Japan
Takasago, Hyogo, Japan
Tamba, Hyogo, Japan
Tatsuno, Hyogo, Japan
Toyooka, Hyogo, Japan
Yabu, Hyogo, Japan
Bando, Ibaraki, Japan
Chikusei, Ibaraki, Japan
Higashiibaraki, Ibaraki, Japan
Hitachinaka, Ibaraki, Japan
Hitachiota, Ibaraki, Japan
Hitachi, Ibaraki, Japan
Inashiki, Ibaraki, Japan
Ishioka, Ibaraki, Japan
Joso, Ibaraki, Japan
Kamisu, Ibaraki, Japan
Kasama, Ibaraki, Japan
Koga, Ibaraki, Japan
Mito, Ibaraki, Japan
Moriya, Ibaraki, Japan
Naka, Ibaraki, Japan
Ryugasaki, Ibaraki, Japan
Sashima, Ibaraki, Japan
Takahagi, Ibaraki, Japan
Toride, Ibaraki, Japan
Tsuchiura, Ibaraki, Japan
Tsukubamirai, Ibaraki, Japan
Tsukuba, Ibaraki, Japan
Ushiku, Ibaraki, Japan
Yuki, Ibaraki, Japan
Hakusan, Ishikawa, Japan
Kahoku, Ishikawa, Japan
Kanazawa, Ishikawa, Japan
Komatsu, Ishikawa, Japan
Nanao, Ishikawa, Japan
Suzu, Ishikawa, Japan
Wajima, Ishikawa, Japan
Hanamaki, Iwate, Japan
Ichinoseki, Iwate, Japan
Kamaishi, Iwate, Japan
Kitakami, Iwate, Japan
Miyako, Iwate, Japan
Morioka, Iwate, Japan
Ninohe, Iwate, Japan
Oshu, Iwate, Japan
Tono, Iwate, Japan
Ayauta, Kagawa, Japan
Kanonji, Kagawa, Japan
Kita, Kagawa, Japan
Marugame, Kagawa, Japan
Mitoyo, Kagawa, Japan
Sakaide, Kagawa, Japan
Sanuki, Kagawa, Japan
Shozu, Kagawa, Japan
Takamatsu, Kagawa, Japan
Aira, Kagoshima, Japan
Amami, Kagoshima, Japan
Hioki, Kagoshima, Japan
Ibusuki, Kagoshima, Japan
Ichikikushikino, Kagoshima, Japan
Izumi, Kagoshima, Japan
Kanoya, Kagoshima, Japan
Kirishima, Kagoshima, Japan
Makurazaki, Kagoshima, Japan
Minamikyushu, Kagoshima, Japan
Nishinomote, Kagoshima, Japan
Satsumasendai, Kagoshima, Japan
Satsuma, Kagoshima, Japan
Shibushi, Kagoshima, Japan
Soh, Kagoshima, Japan
So, Kagoshima, Japan
Ashigarashimo, Kanagawa, Japan
Atsugi, Kanagawa, Japan
Chigasaki, Kanagawa, Japan
Ebina, Kanagawa, Japan
Fujisawa, Kanagawa, Japan
Hiratsuka, Kanagawa, Japan
Isehara, Kanagawa, Japan
Kamakura, Kanagawa, Japan
Kawasaki, Kanagawa, Japan
Miura, Kanagawa, Japan
Naka, Kanagawa, Japan
Odawara, Kanagawa, Japan
Sagamihara, Kanagawa, Japan
Yamato, Kanagawa, Japan
Yokohama, Kanagawa, Japan
Yokosuka, Kanagawa, Japan
Zama, Kanagawa, Japan
Aki, Kochi, Japan
Muroto, Kochi, Japan
Nagaoka, Kochi, Japan
Nankoku, Kochi, Japan
Takaoka, Kochi, Japan
Amakusa, Kumamoto, Japan
Arao, Kumamoto, Japan
Aso, Kumamoto, Japan
Hitoyoshi, Kumamoto, Japan
Kamiamakusa, Kumamoto, Japan
Kamimashiki, Kumamoto, Japan
Koshi, Kumamoto, Japan
Minamata, Kumamoto, Japan
Tamana, Kumamoto, Japan
Uki, Kumamoto, Japan
Yamaga, Kumamoto, Japan
Yatsushiro, Kumamoto, Japan
Fukuchiyama, Kyoto, Japan
Joyo, Kyoto, Japan
Kameoka, Kyoto, Japan
Kizugawa, Kyoto, Japan
Kyotanabe, Kyoto, Japan
Maizuru, Kyoto, Japan
Nagaokakyo, Kyoto, Japan
Nantan, Kyoto, Japan
Soraku, Kyoto, Japan
Tsuzuki, Kyoto, Japan
Uji, Kyoto, Japan
Yosa, Kyoto, Japan
Iga, Mie, Japan
Ise, Mie, Japan
Kameyama, Mie, Japan
Kumano, Mie, Japan
Kuwana, Mie, Japan
Matsusaka, Mie, Japan
Suzuka, Mie, Japan
Tsu, Mie, Japan
Watarai, Mie, Japan
Yokkaichi, Mie, Japan
Ishinomaki, Miyagi, Japan
Iwanuma, Miyagi, Japan
Kesennuma, Miyagi, Japan
Kurihara, Miyagi, Japan
Kurokawa, Miyagi, Japan
Natori, Miyagi, Japan
Osaki, Miyagi, Japan
Oshika, Miyagi, Japan
Sendai, Miyagi, Japan
Shibata, Miyagi, Japan
Shiogama, Miyagi, Japan
Toda, Miyagi, Japan
Tome, Miyagi, Japan
Higashimorokata, Miyazaki, Japan
Hyuga, Miyazaki, Japan
Kobayashi, Miyazaki, Japan
Koyu, Miyazaki, Japan
Kushima, Miyazaki, Japan
Miyakonojo, Miyazaki, Japan
Nichinan, Miyazaki, Japan
Nishiusuki, Miyazaki, Japan
Nobeoka, Miyazaki, Japan
Saito, Miyazaki, Japan
Azumino, Nagano, Japan
Chikuma, Nagano, Japan
Chino, Nagano, Japan
Hanishina, Nagano, Japan
Higashichikuma, Nagano, Japan
Iida, Nagano, Japan
Ina, Nagano, Japan
Kamiminochi, Nagano, Japan
Kiso, Nagano, Japan
Kitaazumi, Nagano, Japan
Kitasaku, Nagano, Japan
Komagane, Nagano, Japan
Komoro, Nagano, Japan
Matsumoto, Nagano, Japan
Okaya, Nagano, Japan
Saku, Nagano, Japan
Shimoina, Nagano, Japan
Shiojiri, Nagano, Japan
Suwa, Nagano, Japan
Suzaka, Nagano, Japan
Ueda, Nagano, Japan
Goto, Nagasaki, Japan
Higashisonogi, Nagasaki, Japan
Isahaya, Nagasaki, Japan
Kitamatsuura, Nagasaki, Japan
Minamishimabara, Nagasaki, Japan
Nishisonogi, Nagasaki, Japan
Omura, Nagasaki, Japan
Sasebo, Nagasaki, Japan
Shimabara, Nagasaki, Japan
Tsushima, Nagasaki, Japan
Unzen, Nagasaki, Japan
Gose, Nara, Japan
Ikoma, Nara, Japan
Kashiba, Nara, Japan
Kashihara, Nara, Japan
Kitakatsuragi, Nara, Japan
Sakurai, Nara, Japan
Tenri, Nara, Japan
Uda, Nara, Japan
Yamatokoriyama, Nara, Japan
Yamatotakada, Nara, Japan
Yoshino, Nara, Japan
Gosen, Niigata, Japan
Joetsu, Niigata, Japan
Kashiwazaki, Niigata, Japan
Minamiuonuma, Niigata, Japan
Mitsuke, Niigata, Japan
Murakami, Niigata, Japan
Nagaoka, Niigata, Japan
Ojiya, Niigata, Japan
Sado, Niigata, Japan
Sanjo, Niigata, Japan
Shibata, Niigata, Japan
Uonuma, Niigata, Japan
Hita, Oita, Japan
Kunisaki, Oita, Japan
Kusu, Oita, Japan
Nakatsu, Oita, Japan
Saiki, Oita, Japan
Tsukumi, Oita, Japan
Usa, Oita, Japan
Usuki, Oita, Japan
Yufu, Oita, Japan
Akaiwa, Okayama, Japan
Asakuchi, Okayama, Japan
Bizen, Okayama, Japan
Kaga, Okayama, Japan
Kasaoka, Okayama, Japan
Kume, Okayama, Japan
Kurashiki, Okayama, Japan
Mimasaka, Okayama, Japan
Niimi, Okayama, Japan
Soja, Okayama, Japan
Takahashi, Okayama, Japan
Tamano, Okayama, Japan
Tomata, Okayama, Japan
Tsuyama, Okayama, Japan
Ginowan, Okinawa, Japan
Ishigaki, Okinawa, Japan
Itoman, Okinawa, Japan
Kunigami, Okinawa, Japan
Miyakojima, Okinawa, Japan
Naha, Okinawa, Japan
Nakagami, Okinawa, Japan
Nanjo, Okinawa, Japan
Tomigusuku, Okinawa, Japan
Urasoe, Okinawa, Japan
Uruma, Okinawa, Japan
Daito, Osaka, Japan
Fujiidera, Osaka, Japan
Habikino, Osaka, Japan
Hannan, Osaka, Japan
Higashiosaka, Osaka, Japan
Hirakata, Osaka, Japan
Ibaraki, Osaka, Japan
Ikeda, Osaka, Japan
Izumiotsu, Osaka, Japan
Izumisano, Osaka, Japan
Izumi, Osaka, Japan
Kadoma, Osaka, Japan
Kaizuka, Osaka, Japan
Kashiwara, Osaka, Japan
Katano, Osaka, Japan
Kawachinagano, Osaka, Japan
Kishiwada, Osaka, Japan
Matsubara, Osaka, Japan
Mino, Osaka, Japan
Moriguchi, Osaka, Japan
Neyagawa, Osaka, Japan
Osakasayama, Osaka, Japan
Sakai, Osaka, Japan
Sennan, Osaka, Japan
Settsu, Osaka, Japan
Suita, Osaka, Japan
Takaishi, Osaka, Japan
Takatsuki, Osaka, Japan
Tondabayashi, Osaka, Japan
Toyonaka, Osaka, Japan
Toyono, Osaka, Japan
Yao, Osaka, Japan
Imari, Saga, Japan
Kanzaki, Saga, Japan
Karatsu, Saga, Japan
Kishima, Saga, Japan
Nishimatsuura, Saga, Japan
Ogi, Saga, Japan
Takeo, Saga, Japan
Taku, Saga, Japan
Tosu, Saga, Japan
Ureshino, Saga, Japan
Ageo, Saitama, Japan
Asaka, Saitama, Japan
Chichibu, Saitama, Japan
Fujimino, Saitama, Japan
Fujimi, Saitama, Japan
Fukaya, Saitama, Japan
Gyoda, Saitama, Japan
Hanno, Saitama, Japan
Hanyu, Saitama, Japan
Hasuda, Saitama, Japan
Hidaka, Saitama, Japan
Hiki, Saitama, Japan
Honjo, Saitama, Japan
Iruma, Saitama, Japan
Kasukabe, Saitama, Japan
Kawagoe, Saitama, Japan
Kawaguchi, Saitama, Japan
Kazo, Saitama, Japan
Kitaadachi, Saitama, Japan
Kitamoto, Saitama, Japan
Konosu, Saitama, Japan
Koshigaya, Saitama, Japan
Kuki, Saitama, Japan
Kumagaya, Saitama, Japan
Minamisaitama, Saitama, Japan
Niiza, Saitama, Japan
Sakado, Saitama, Japan
Sayama, Saitama, Japan
Soka, Saitama, Japan
Toda, Saitama, Japan
Tokorozawa, Saitama, Japan
Tsurugashima, Saitama, Japan
Wako, Saitama, Japan
Yoshikawa, Saitama, Japan
Higashiomi, Shiga, Japan
Hikone, Shiga, Japan
Inukami, Shiga, Japan
Koka, Shiga, Japan
Kusatsu, Shiga, Japan
Moriyama, Shiga, Japan
Nagahama, Shiga, Japan
Omihachiman, Shiga, Japan
Otsu, Shiga, Japan
Ritto, Shiga, Japan
Takashima, Shiga, Japan
Hamada, Shimane, Japan
Izumo, Shimane, Japan
Kanoashi, Shimane, Japan
Matsue, Shimane, Japan
Nita, Shimane, Japan
Oda, Shimane, Japan
Unnan, Shimane, Japan
Yasugi, Shimane, Japan
Atami, Shizuoka, Japan
Fujieda, Shizuoka, Japan
Fujinomiya, Shizuoka, Japan
Fuji, Shizuoka, Japan
Fukuroi, Shizuoka, Japan
Gotemba, Shizuoka, Japan
Haibara, Shizuoka, Japan
Hamamatsu, Shizuoka, Japan
Ito, Shizuoka, Japan
Iwata, Shizuoka, Japan
Izu, Shizuoka, Japan
Kakegawa, Shizuoka, Japan
Kamo, Shizuoka, Japan
Kikugawa, Shizuoka, Japan
Kosai, Shizuoka, Japan
Mishima, Shizuoka, Japan
Numazu, Shizuoka, Japan
Omaezaki, Shizuoka, Japan
Shimada, Shizuoka, Japan
Shimoda, Shizuoka, Japan
Susono, Shizuoka, Japan
Tagata, Shizuoka, Japan
Ashikaga, Tochigi, Japan
Haga, Tochigi, Japan
Kanuma, Tochigi, Japan
Kawachi, Tochigi, Japan
Moka, Tochigi, Japan
Nasukarasuyama, Tochigi, Japan
Nasu, Tochigi, Japan
Nikko, Tochigi, Japan
Otawara, Tochigi, Japan
Oyama, Tochigi, Japan
Sano, Tochigi, Japan
Utsunomiya, Tochigi, Japan
Anan, Tokushima, Japan
Awa, Tokushima, Japan
Itano, Tokushima, Japan
Mima, Tokushima, Japan
Miyoshi, Tokushima, Japan
Myozai, Tokushima, Japan
Naka, Tokushima, Japan
Naruto, Tokushima, Japan
Yoshinogawa, Tokushima, Japan
Adachi, Tokyo, Japan
Akiruno, Tokyo, Japan
Akishima, Tokyo, Japan
Arakawa, Tokyo, Japan
Bunkyo, Tokyo, Japan
Chiyoda, Tokyo, Japan
Chofu, Tokyo, Japan
Chuo, Tokyo, Japan
Edogawa, Tokyo, Japan
Fuchu, Tokyo, Japan
Fussa, Tokyo, Japan
Hachioji, Tokyo, Japan
Higashiyamato, Tokyo, Japan
Hino, Tokyo, Japan
Inagi, Tokyo, Japan
Itabashi, Tokyo, Japan
Katsushika, Tokyo, Japan
Kita, Tokyo, Japan
Kiyose, Tokyo, Japan
Kodaira, Tokyo, Japan
Koganei, Tokyo, Japan
Kokubunji, Tokyo, Japan
Komae, Tokyo, Japan
Koto, Tokyo, Japan
Kunitachi, Tokyo, Japan
Machida, Tokyo, Japan
Meguro, Tokyo, Japan
Minato, Tokyo, Japan
Mitaka, Tokyo, Japan
Musashino, Tokyo, Japan
Nakano, Tokyo, Japan
Nerima, Tokyo, Japan
Nishitokyo, Tokyo, Japan
Ome, Tokyo, Japan
Ota, Tokyo, Japan
Setagaya, Tokyo, Japan
Shibuya, Tokyo, Japan
Shinagawa, Tokyo, Japan
Shinjuku, Tokyo, Japan
Suginami, Tokyo, Japan
Sumida, Tokyo, Japan
Tachikawa, Tokyo, Japan
Tama, Tokyo, Japan
Toshima, Tokyo, Japan
Hino, Tottori, Japan
Iwami, Tottori, Japan
Kurayoshi, Tottori, Japan
Saihaku, Tottori, Japan
Sakaiminato, Tottori, Japan
Yazu, Tottori, Japan
Yonago, Tottori, Japan
Himi, Toyama, Japan
Imizu, Toyama, Japan
Nakaniikawa, Toyama, Japan
Namerikawa, Toyama, Japan
Nanto, Toyama, Japan
Takaoka, Toyama, Japan
Uozu, Toyama, Japan
Arida, Wakayama, Japan
Gobo, Wakayama, Japan
Ito, Wakayama, Japan
Iwade, Wakayama, Japan
Kainan, Wakayama, Japan
Kinokawa, Wakayama, Japan
Nishimuro, Wakayama, Japan
Tanabe, Wakayama, Japan
Nanyo, Yamagata, Japan
Sakata, Yamagata, Japan
Tendo, Yamagata, Japan
Tsuruoka, Yamagata, Japan
Yonezawa, Yamagata, Japan
Hagi, Yamaguchi, Japan
Hikari, Yamaguchi, Japan
Hofu, Yamaguchi, Japan
Iwakuni, Yamaguchi, Japan
Nagato, Yamaguchi, Japan
SanyoOnoda, Yamaguchi, Japan
Shimonoseki, Yamaguchi, Japan
Shunan, Yamaguchi, Japan
Ube, Yamaguchi, Japan
Yanai, Yamaguchi, Japan
Chuo, Yamanashi, Japan
Fuefuki, Yamanashi, Japan
Fujiyoshida, Yamanashi, Japan
Hokuto, Yamanashi, Japan
Kai, Yamanashi, Japan
Kofu, Yamanashi, Japan
Minamitsuru, Yamanashi, Japan
Nirasaki, Yamanashi, Japan
Otsuki, Yamanashi, Japan
Tsuru, Yamanashi, Japan
Aichi, Japan
Akita, Japan
Aomori, Japan
Chiba, Japan
Fukui, Japan
Fukuoka, Japan
Fukushima, Japan
Gifu, Japan
Hiroshima, Japan
Ishikawa, Japan
Iwate, Japan
Kagoshima, Japan
Kochi, Japan
Kumamoto, Japan
Kyoto, Japan
Mie, Japan
Miyagi, Japan
Miyazaki, Japan
Nagano, Japan
Nagasaki, Japan
Nara, Japan
Niigata, Japan
Oita, Japan
Okayama, Japan
Okinawa, Japan
Osaka, Japan
Saga, Japan
Saitama, Japan
Shizuoka, Japan
Tochigi, Japan
Tokushima, Japan
Tottori, Japan
Toyama, Japan
Wakayama, Japan
Yamagata, Japan
Yamaguchi, Japan
Sponsors and Collaborators
Eisai Co., Ltd.
Study Director: Kenta Sumitomo Drug Fostering and Evolution Coordination Department, Eisai Co., Ltd.
  More Information

Responsible Party: Eisai Co., Ltd. Identifier: NCT01129596     History of Changes
Other Study ID Numbers: ART05T 
Study First Received: May 21, 2010
Last Updated: February 23, 2017

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders
Cholinesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Cholinergic Agents
Neurotransmitter Agents
Physiological Effects of Drugs
Nootropic Agents processed this record on February 27, 2017