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Trial record 1 of 1 for:    CONNECT CLL
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Connect™ CLL: The Chronic Lymphocytic Leukemia Disease Registry

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Celgene Corporation
ClinicalTrials.gov Identifier:
NCT01081015
First received: March 4, 2010
Last updated: February 20, 2015
Last verified: February 2015
  Purpose

The purpose of the Connect™ Chronic Lymphocytic Leukemia (CLL) Disease Registry is to explore the history and real world management of patients diagnosed with CLL, provide insight into the management of CLL, and evaluate the effectiveness of first, second and subsequent therapeutic strategies employed in both the community and academic settings.


Condition
Chronic Lymphocytic Leukemia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Connect™ CLL: The Chronic Lymphocytic Leukemia Disease Registry

Resource links provided by NLM:


Further study details as provided by Celgene Corporation:

Primary Outcome Measures:
  • Identify and summarize patterns in therapeutic regimens and patient outcomes [ Time Frame: up to 8 years ] [ Designated as safety issue: No ]
    The primary objective is to 1) describe practice patterns of first line therapy regimens and subsequent therapeutic strategies in patients initiated on therapy for CLL, as well as initiated on second line and subsequent therapies, in the community and academic setting (2) Provide insight into therapeutic regimens and therapy sequence in clinical practice as they relate to clinical outcomes in patients initiated on first-line, second-line or subsequent therapies for CLL.


Secondary Outcome Measures:
  • Summarize Effectiveness of Treatment Regimens [ Time Frame: up to 8 years ] [ Designated as safety issue: No ]
    Describe any differences in effectiveness associated with treatment regimens, including first-line regimens and subsequent therapeutic strategies in patients actively treated for CLL

  • Health Related Quality of Life Measures Related to Therapeutic Regimens [ Time Frame: up to 8 years ] [ Designated as safety issue: No ]
    Describe the health-related quality of life of patients actively treated for CLL, and to explore the association of HRQoL with therapeutic regimens, sequences and clinical outcomes.


Enrollment: 1494
Study Start Date: September 2009
Estimated Study Completion Date: January 2019
Estimated Primary Completion Date: January 2019 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

An adult population (>=18 years old) of both men and women who have chronic lymphocytic leukemia treated in either community or academic medical centers.

Criteria

Inclusion Criteria:

  • Clinical diagnosis with CLL
  • Clinical decision made to initiate first-line therapy, second-line therapy or subsequent line of therapy prior to enrollment into the ConnectTM CLL registry, but within 2 months of enrollment
  • Age≥18 years
  • Willing and able to provide signed informed consent
  • Willing and able to complete patient assessment questionnaires either alone or with minimal assistance from caregivers and/or trained site personnel

Exclusion Criteria:

  • Participation in a clinical study in which study treatment is blinded
  • Patient condition is considered terminal (i.e.<6 months to live)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01081015

  Hide Study Locations
Locations
United States, California
New Hope Cancer & Research Institute
Pomona, California, United States, 91767
United States, Florida
Medical Specialists of the Palm Beaches
Atlantis, Florida, United States, 33462
Thomas Niederman, MD
Boynton Beach, Florida, United States, 33435
University Cancer Institute
Boynton Beach, Florida, United States, 33426
Pasco Hernando Oncology Associates (Kumar)
New Port Richey, Florida, United States, 34652
United States, Georgia
Phoebe Putney Memorial Hospital
Albany, Georgia, United States, 31701
Peachtree Hematology-Oncology Consultants
Atlanta, Georgia, United States, 30318
Georgia Cancer Specialists
Atlanta, Georgia, United States, 30331
US Oncology - Dublin Hematology & Oncology
Dublin, Georgia, United States, 31021
United States, Hawaii
Straub Clinic and Hospital
Honolulu, Hawaii, United States, 96816
United States, Illinois
US Oncology - Cancer Care & Hematology Specialists of Chicagoland - Arlington
Arlington Heights, Illinois, United States, 60005
John H. Stroger, Jr., Hospital of Cook County
Chicago, Illinois, United States, 60612
Rush University Medical Center
Chicago, Illinois, United States, 60612
Ingalls Cancer Research Center
Harvey, Illinois, United States, 60426
Elmhurst Memorial Hospital
Lombard, Illinois, United States, 60148
Oncology Specialists, S.C.
Niles, Illinois, United States, 60714
US Oncology - Cancer Care & Hematology Specialists of Chicagoland - Niles
Niles, Illinois, United States, 60714
Illinois Cancer Care
Peoria, Illinois, United States, 61615
Orchard Research
Skokie, Illinois, United States, 60076
Carle Cancer Center
Urbana, Illinois, United States, 61801
US Oncology - Cancer Care & Hematology Specialists of Chicagoland - Winfield
Winfield, Illinois, United States, 60190
United States, Indiana
St. Francis Cancer Research
Beech Grove, Indiana, United States, 46107
Center for Cancer Care @ Goshen Health Systems
Goshen, Indiana, United States, 46526
Indiana University Cancer Center Clinical Research Office
Indianapolis, Indiana, United States, 46202
Cancer Care Partners, LLC
Mishawaka, Indiana, United States, 46545
Cancer Care Center, Inc.
New Albany, Indiana, United States, 47150
United States, Iowa
McFarland Clinic
Ames, Iowa, United States, 50010
Hematology Oncology Associates of the Quad Cities
Bettendorf, Iowa, United States, 52722
Iowa Blood and Cancer Care of PCI
Cedar Rapids, Iowa, United States, 52402
Covenant Clinic
Waterloo, Iowa, United States, 50702
United States, Kansas
Cancer Center of Kansas, PA
Wichita, Kansas, United States, 67214
United States, Louisiana
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, United States, 70809
United States, Maryland
Western Maryland Health System, Inc.
Cumberland, Maryland, United States, 21502
Alliance Hematology Oncology, PA
Westminster, Maryland, United States, 21157
United States, Massachusetts
Capecod Hospital / Davenport Mugar Cancer Center
Hyannis, Massachusetts, United States, 02601
Fallon Clinic
Worcester, Massachusetts, United States, 01608
United States, Michigan
Michigan State University / McLaren Regional Medical Center
Flint, Michigan, United States, 48532
Cancer and Hematology Centers of Western Michigan
Grand Rapids, Michigan, United States, 49503
West Michigan Cancer Center
Kalamazoo, Michigan, United States, 49007
United States, Minnesota
Duluth Clinic Cancer Center
Duluth, Minnesota, United States, 55805
Park Nicollet Institute - Louisiana Ave.
St. Louis Park, Minnesota, United States, 55426
Park Nicollet Institute Metro - MN CCOP
St. Louis Park, Minnesota, United States, 55416
United States, Mississippi
US Oncology - University of Tennessee Cancer Institute - Southaven
Southaven, Mississippi, United States, 38671
United States, Missouri
US Oncology - Missouri Cancer Associates
Columbia, Missouri, United States, 65201
Capitol Comprehensive Cancer Care Clinic
Jefferson City, Missouri, United States, 65109
St. John's Medical Research Institute
Springfield, Missouri, United States, 65807
St. Joseph Oncology, Inc.
St. Joseph, Missouri, United States, 64507
Hematology Oncology Consultants, Inc.
St. Louis, Missouri, United States, 63136
United States, Montana
Montana Cancer Institute Foundation
Missoula, Montana, United States, 59802
United States, Nebraska
Nebraska Hematology Oncology, PC
Lincoln, Nebraska, United States, 68506
Southeast Nebraska Hematology & Oncology Consultants, PC
Lincoln, Nebraska, United States, 68510
United States, Nevada
Southern Nevada Cancer Research Foundation
Las Vegas, Nevada, United States, 89106
VA Sierra Nevada Healthcare System
Reno, Nevada, United States, 89502
United States, New Jersey
The Center for Cancer and Hematologic Disease
Cherry Hill, New Jersey, United States, 08003
Drs. Forte, Schleider, Attas & Condemi, PA
Englewood, New Jersey, United States, 07432
Charles Farber, MD
Morristown, New Jersey, United States, 07962
Hematology Oncology of Northern New Jersey
Morristown, New Jersey, United States, 07962
Steeplechase Cancer Center
Somerville, New Jersey, United States, 08876
United States, New York
Samuel S Stratton VAMC
Albany, New York, United States, 12208
Hematology Oncology Associates of Western Suffolk
Bay Shore, New York, United States, 11706
Bronx River Medical Associates
Bronx, New York, United States, 10467
Eastchester Center for Cancer Care
Bronx, New York, United States, 10469
Eduardo Saponara, MD
Bronxville, New York, United States, 10708
Jonah Cancer Care Center & ECMC
Buffalo, New York, United States, 14215
Broome Oncology
Johnson City, New York, United States, 13790
SUNY Upstate Medical University - Adult Program
Syracuse, New York, United States, 14222
United States, North Carolina
US Oncology - Cancer Centers of North Carolina - Cary
Cary, North Carolina, United States, 27518
US Oncology - Cancer Centers of North Carolina - Macon
Raleigh, North Carolina, United States, 27607
US Oncology - Cancer Centers of North Carolina - Falls
Raleigh, North Carolina, United States, 27614
United States, North Dakota
Legacy Pharma Research
Bismarck, North Dakota, United States, 58501
Roger Maris Cancer Center
Fargo, North Dakota, United States, 58122
United States, Ohio
Summa Health System - Cancer Research Office
Akron, Ohio, United States, 44304
Gabrail Cancer Center Research
Canton, Ohio, United States, 44718
Mid Ohio Oncology / Hematology, Inc.
Columbus, Ohio, United States, 43219
Hematology Oncology Center, Inc.
Elyria, Ohio, United States, 44035
United States, Oregon
US Oncology - Willamette Valley Cancer Institute - Eugene
Eugene, Oregon, United States, 97401-8122
US Oncology - Northwest Cancer Specialists, PC - Portland - Barnes
Portland, Oregon, United States, 97225
US Oncology - Northwest Cancer Specialists, PC - Portland - Broadway
Portland, Oregon, United States, 97227
US Oncology - Northwest Cancer Specialists, PC - Portland - Hoyt
Portland, Oregon, United States, 97213-2996
US Oncology - Willamette Valley Cancer Institute - Springfield
Springfield, Oregon, United States, 97477
US Oncology - Northwest Cancer Specialists, PC - Tualatin
Tualatin, Oregon, United States, 97062
United States, Pennsylvania
Oncology Hematology of Lehigh Valley
Bethlehem, Pennsylvania, United States, 18015
Consultants in Medical Oncology and Hematology, PC
Drexel Hill, Pennsylvania, United States, 19026
Gettysburg Cancer Center
Gettysburg, Pennsylvania, United States, 17325
Andrews and Patel Associates
Harrisburg, Pennsylvania, United States, 17111
US Oncology - Medical Oncology Associates (Nahar)
Kingston, Pennsylvania, United States, 18704
Lancaster Cancer Center
Lancaster, Pennsylvania, United States, 17605
Berks Hematology Oncology Associates
Reading, Pennsylvania, United States, 19612
United States, Rhode Island
Hematology & Oncology Associates of Rhode Island
Cranston, Rhode Island, United States, 02920
United States, South Carolina
Charleston Hematology Oncology Associates, PA
Charleston, South Carolina, United States, 29403
South Carolina Oncololgy Associates, PA
Columbia, South Carolina, United States, 29210
US Oncology - Cancer Centers of the Carolinas - Easley
Easley, South Carolina, United States, 29640
US Oncology - Cancer Centers of the Carolinas - West Faris
Greenville, South Carolina, United States, 29605
US Oncology - Cancer Centers of the Carolinas - Butternut
Greenville, South Carolina, United States, 29605
US Oncology - Cancer Centers of the Carlinas - Eastside
Greenville, South Carolina, United States, 29615
US Oncology - Cancer Centers of the Carolinas - Seneca
Seneca, South Carolina, United States, 29672
US Oncology - Cancer Centers of the Carolinas - Spartanburg
Spartanburg, South Carolina, United States, 29307
United States, South Dakota
Sanford Clinic
Sioux Falls, South Dakota, United States, 57104
United States, Tennessee
US Oncology - University of Tennessee Cancer Institute - Bartlett
Bartlett, Tennessee, United States, 38133
Family Cancer Center, PLLC
Collierville, Tennessee, United States, 38017
US Oncology - University of Tennessee Cancer Institute - Germantown
Germantown, Tennessee, United States, 38138
US Oncology - University of Tennessee Cancer Institute - Memphis
Memphis, Tennessee, United States, 38104
SCRI
Nashville, Tennessee, United States, 37203
United States, Texas
US Oncology - Texas Cancer Center - Abilene (South)
Abilene, Texas, United States, 79606
US Oncology - Texas Oncology, PA - Amarillo
Amarillo, Texas, United States, 79106
US Oncology - Texas Oncology - Arlington South
Arlington, Texas, United States, 76014
US Oncology - Texas Oncology, PA - Bedford
Bedford, Texas, United States, 76022
St. Joseph Regional Cancer Center
Bryan, Texas, United States, 77802
Scott & White Clinic
College Station, Texas, United States, 77802
Coastal Bend Cancer Center
Corpus Christi, Texas, United States, 78463
South Texas Institute of Cancer
Corpus Christi, Texas, United States, 78405
US Oncology - Texas Oncology, PA - Dallas
Dallas, Texas, United States, 75231
US Oncology - El Paso Cancer Treatment Center
El Paso, Texas, United States, 79902
US Oncology - El Paso Cancer Treatment Center - West
El Paso, Texas, United States, 79902
US Oncology - Southwest Fort Worth Cancer Center
Fort Worth, Texas, United States, 76132
US Oncology - Texas Oncology, PA - Fort Worth
Fort Worth, Texas, United States, 76104
US Oncology - Texas Oncology - Grapevine
Grapevine, Texas, United States, 76051
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Oncology Consultants
Houston, Texas, United States, 77024
US Oncology - San Antonio Tumor & Blood Clinic - Kerrville
Kerrville, Texas, United States, 78028
Wilford Hall Medical Center
Lackland AFB, Texas, United States, 78236
US Oncology - Longview Cancer Center
Longview, Texas, United States, 75601
Joe Arrington Cancer Research and Treatment Center
Lubbock, Texas, United States, 79410
US Oncology - Texas Oncology - McAllen
McAllen, Texas, United States, 78503
US Oncology - Texas Oncology - Mesquite
Mesquite, Texas, United States, 75150
US Oncology - Allison Cancer Center
Midland, Texas, United States, 79701
US Oncology - Texas Oncology - Paris
Paris, Texas, United States, 75460-5004
US Oncology - Cancer Care Centers of South Texas
San Antonio, Texas, United States, 78217
US Oncology - San Antonio Tumor & Blood Clinic - M. Oak
San Antonio, Texas, United States, 78258-3912
US Oncology - Texas Oncology - Sherman
Sherman, Texas, United States, 75090-0504
Scott & White Healthcare Department of Research
Temple, Texas, United States, 76508
US Oncology - Texas Oncology - Tyler
Tyler, Texas, United States, 75702
ETMC dba Tyler Hematology Oncology
Tyler, Texas, United States, 75701
ETMC dba Blood and Cancer Center - East Texas
Tyler, Texas, United States, 75701
US Oncology - Texas Oncology Cancer Care and Research Center
Waco, Texas, United States, 76712
US Oncology - Texas Oncology - Weslaco
Weslaco, Texas, United States, 78596
US Oncology - Texoma Cancer Center
Wichita Falls, Texas, United States, 76310
United States, Utah
Central Utah Clinic
American Fork, Utah, United States, 84003
Northern Utah Associates
Ogden, Utah, United States, 84403
United States, Virginia
US Oncology - Arlington Fairfax Hematology Oncology
Arlington, Virginia, United States, 22205
US Oncology - Onc and Hem Assoc of Southwest VA, Inc - Christiansburg
Christiansburg, Virginia, United States, 24073
US Oncology - Fairfax Northern VA Hem-Onc PC
Fairfax, Virginia, United States, 22031
US Oncology - Fairfax - Northern Virginia Hematology-Oncology, PC - Gainesville
Gainesville, Virginia, United States, 20155
US Oncology - Fairfax - Northern Virginia Hem-Onc, PC - Leesburg
Leesburg, Virginia, United States, 20176
US Oncology - Onc and Hem Assoc of Southwest VA, Inc - Low Moor
Low Moor, Virginia, United States, 24457
US Oncology - Onc and Hem Assoc of Southwest VA, Inc - Roanoke
Roanoke, Virginia, United States, 24014
US Oncology - Onc and Hem Assoc of Southwest VA, Inc - Salem
Salem, Virginia, United States, 24153
US Oncology - Shenandoah Oncology - Winchester
Winchester, Virginia, United States, 22601
US Oncology - Fairfax - Northern Virginia Hem-Onc, PC - Woodbridge
Woodbridge, Virginia, United States, 22191
US Oncology - Onc and Hem Assoc of Southwest VA, Inc - Wytheville
Wytheville, Virginia, United States, 24382
United States, Washington
Peace Health Medical Group
Bellingham, Washington, United States, 98226
US Oncology - Puget Sound Cancer Center - Edmonds
Edmonds, Washington, United States, 98133
Providence Everett Medical Center
Everett, Washington, United States, 98201
Columbia Basin Hematology and Oncology
Kennewick, Washington, United States, 99337
US Oncology - Puget Sound Cancer Center - Seattle
Seattle, Washington, United States, 98133
Medical Oncology Associates PS
Spokane, Washington, United States, 99208
US Oncology - Cancer Care Northwest - Sherman
Spokane, Washington, United States, 99202
US Oncology - Cancer Care Northwest - Mission
Spokane, Washington, United States, 99218
US Oncology - Cancer Care Northwest - Holland
Spokane, Washington, United States, 99218
US Oncology - Northwest Cancer Specialists, PC - Vancouver - 134th St
Vancouver, Washington, United States, 98686
US Oncology - Northwest Cancer Specialists, PC - Vancouver - 136th St.
Vancouver, Washington, United States, 98684
Providence St. Mary Regional Cancer Center
Walla Walla, Washington, United States, 99362
US Oncology - Yakima Valley Memorial Hospital/North Star Lodge (Boyd)
Yakima, Washington, United States, 98902
United States, Wisconsin
St. Vincent Hospital/Green Bay Oncology
Green Bay, Wisconsin, United States, 54301
Waukesha Memorial Hospital
Waukesha, Wisconsin, United States, 53188
Sponsors and Collaborators
Celgene Corporation
Investigators
Study Director: Kenneth Foon, MD Celgene Corporation
  More Information

No publications provided by Celgene Corporation

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Celgene Corporation
ClinicalTrials.gov Identifier: NCT01081015     History of Changes
Other Study ID Numbers: Connect™ CLL
Study First Received: March 4, 2010
Last Updated: February 20, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by Celgene Corporation:
Chronic Lymphocytic Leukemia
CLL
disease registry
Connect™

Additional relevant MeSH terms:
Leukemia
Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Lymphoid
Immune System Diseases
Immunoproliferative Disorders
Leukemia, B-Cell
Lymphatic Diseases
Lymphoproliferative Disorders
Neoplasms
Neoplasms by Histologic Type

ClinicalTrials.gov processed this record on February 27, 2015