Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2015 by National Cancer Institute (NCI)
Sponsor:
Information provided by (Responsible Party):
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT01015833
First received: November 17, 2009
Last updated: May 26, 2015
Last verified: March 2015
  Purpose

This randomized phase III trial studies sorafenib tosylate and doxorubicin hydrochloride to see how well they work compared with sorafenib tosylate alone in treating patients with liver cancer that has spread to nearby tissue or lymph nodes or has spread to other places in the body. Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving sorafenib tosylate together with doxorubicin hydrochloride is more effective than sorafenib tosylate alone in treating liver cancer.


Condition Intervention Phase
Adult Hepatocellular Carcinoma
Advanced Adult Hepatocellular Carcinoma
BCLC Stage C Adult Hepatocellular Carcinoma
BCLC Stage D Adult Hepatocellular Carcinoma
Localized Non-Resectable Adult Liver Carcinoma
Recurrent Adult Liver Carcinoma
Drug: Doxorubicin Hydrochloride
Other: Laboratory Biomarker Analysis
Other: Pharmacological Study
Drug: Sorafenib Tosylate
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: Phase III Randomized Study of Sorafenib Plus Doxorubicin Versus Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)

Resource links provided by NLM:


Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Overall survival [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
    The confidence bound estimates for futility will also be adjusted according to the Lan-DeMets analogue of the O'Brien-Fleming boundaries.


Secondary Outcome Measures:
  • Incidence of adverse events, as assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Up to 3 years ] [ Designated as safety issue: Yes ]
    Incidence of other adverse events (proteinuria, hypertension, and other common side effects of study drugs) will be assessed.

  • Progression free survival [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
    The stratified log-rank test will be used.


Estimated Enrollment: 480
Study Start Date: February 2010
Estimated Primary Completion Date: June 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm I (doxorubicin hydrochloride, sorafenib tosylate)
Patients receive doxorubicin hydrochloride IV on day 1 and sorafenib tosylate PO QD or BID on days 1-21. Treatment repeats every 21 days for 6 courses in the absence of disease progression or unacceptable toxicity. After 6 courses, patients may continue to receive sorafenib tosylate PO QD or BID in the absence of disease progression or unacceptable toxicity.
Drug: Doxorubicin Hydrochloride
Given IV
Other Names:
  • 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI)
  • ADM
  • Adriacin
  • Adriamycin
  • Adriamycin Hydrochloride
  • Adriamycin PFS
  • Adriamycin RDF
  • ADRIAMYCIN, HYDROCHLORIDE
  • Adriamycine
  • Adriblastina
  • Adriblastine
  • Adrimedac
  • Chloridrato de Doxorrubicina
  • DOX
  • DOXO-CELL
  • Doxolem
  • DOXORUBICIN HYDROCHLORIDE
  • Doxorubicin.HCl
  • Doxorubin
  • Farmiblastina
  • FI 106
  • FI-106
  • hydroxydaunorubicin
  • Rubex
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Pharmacological Study
Correlative studies
Drug: Sorafenib Tosylate
Given PO
Other Names:
  • BAY 43-9006 Tosylate
  • BAY 54-9085
  • Nexavar
  • sorafenib
  • SORAFENIB TOSYLATE
Experimental: Arm II (sorafenib tosylate)
Patients receive sorafenib tosylate PO QD or BID on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Pharmacological Study
Correlative studies
Drug: Sorafenib Tosylate
Given PO
Other Names:
  • BAY 43-9006 Tosylate
  • BAY 54-9085
  • Nexavar
  • sorafenib
  • SORAFENIB TOSYLATE

Detailed Description:

PRIMARY OBJECTIVES:

I. Compare the overall survival (OS) of patients treated with sorafenib (sorafenib tosylate) and doxorubicin (doxorubicin hydrochloride) to that of those treated with sorafenib.

SECONDARY OBJECTIVES:

I. Compare time to progression (TTP) of patients treated with sorafenib and doxorubicin to that of those treated with sorafenib.

II. Compare progression-free-survival (PFS) of patients treated with sorafenib and doxorubicin to that of those treated with sorafenib.

III. Compare tumor response using Response Evaluation Criteria in Solid Tumors (RECIST) criteria of patients treated with sorafenib and doxorubicin to that of those treated with sorafenib.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive doxorubicin hydrochloride intravenously (IV) on day 1 and sorafenib tosylate orally (PO) once daily (QD) or twice daily (BID) on days 1-21. Treatment repeats every 21 days for 6 courses in the absence of disease progression or unacceptable toxicity. After 6 courses, patients may continue to receive sorafenib tosylate PO QD or BID in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive sorafenib tosylate PO QD or BID on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 1 year and then every 6 months for 2 years.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients must have pathologically or cytologically proven hepatocellular carcinoma; known mixed histology (e.g. hepatocellular carcinoma plus cholangiocarcinoma) or fibrolamellar variant is not allowed
  • Patients must have locally advanced or metastatic disease; locally advanced disease is defined as disease deemed to be unresectable or non-eligible for transplant without distant metastases
  • Lesions must be accurately measurable in at least one dimension (longest diameter to be recorded) as >= 2 cm with conventional techniques or as >= 1 cm with spiral computed tomography (CT) scan
  • No prior adjuvant sorafenib or other v-RAF-1 murine leukemia viral oncogene homolog (Raf)/vascular endothelial growth factor (VEGF) inhibitors; other prior adjuvant therapy is allowed if completed > 6 months prior to registration with documented recurrence of hepatocellular carcinoma (HCC)
  • Patients may have been treated with loco regional therapies provided that they either have:

    • A target lesion that has not been subjected to local therapy or
    • The target lesion(s) within the field of the local therapy has shown an increase of >= 20% in the size since last treatment

      • Such therapy must be completed at least 4 weeks prior to registration; patients that have received palliative radiation therapy to the bone need not wait 4 weeks to begin protocol therapy
  • Prior therapies allowed include the following:

    • Bland embolization, radiation, radioactive microspheres, etc
    • Chemoembolization using any chemotherapy (except, see below)
    • Chemoembolization drug-eluting beads using doxorubicin
    • Prior therapy with chemoembolization using doxorubicin in the non drug eluting beads form is NOT allowed
  • No prior systemic therapy for metastatic disease
  • No prior exposure to systemic doxorubicin administered intravenously
  • Antiviral treatment is allowed, however interferon therapy must be stopped at least 4 weeks prior to registration
  • Allografts are not allowed: no prior history of any allograft, including but not limited to liver and bone marrow transplants
  • Patients must have completed any major surgery >= 4 weeks from registration
  • Concomitant treatment with Rifampin or St John's Wort is not allowed; patients should discontinue these drugs at least 4 weeks prior to registration
  • No known central nervous system (CNS) tumors including brain metastases
  • No clinically significant gastrointestinal bleeding events requiring intervention, transfusion, or admission to hospital within 30 days prior to registration
  • Patients with a history of hypertension should be well controlled (< 140/90 mmHg) on a regimen of anti-hypertensive therapy
  • Significant history of cardiac disease is not allowed:

    • Congestive heart failure > class II New York Heart Association (NYHA)
    • Myocardial infarction within 6 months prior to registration
    • Serious myocardial dysfunction, defined as scintigraphically (multigated acquisition scan [MUGA], myocardial scintigram) determined absolute left ventricular ejection fraction (LVEF) below 45% or an LVEF on echocardiogram (ECHO) below the normal limit at the individual institution
  • No history of bleeding diathesis
  • Patients receiving combination anti-retroviral therapy for human immunodeficiency virus (HIV) are excluded from the study
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
  • Pregnancy/nursing status: women who are pregnant should not go on study; women should not breastfeed while participating in this study
  • Granulocytes >= 1,500/uL
  • Hemoglobin >= 8.5 g/dL; patients with recent or ongoing gastrointestinal bleed may not be transfused to reach the entry hemoglobin of 8.5 g/dL; physicians should ensure patients requiring transfusion prior to registration do not have an occult or clinically apparent gastrointestinal bleed
  • Platelets >= 75,000/uL
  • Creatinine =< 1.5 x upper limit of normal (ULN) (or creatinine clearance calculated >= 60 cc/minute)
  • Child-Pugh score A; patients must meet all laboratory value requirements
  • Bilirubin =< 3 mg/dL
  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 5 x ULN
  • Prothrombin time (PT)-international normalized ratio (INR) =< 1.7 (not required for patients on anticoagulation agents; patients who are being therapeutically anticoagulated with an agent such as Coumadin or heparin will be allowed to participate provided that no prior evidence of underlying abnormality in these parameters exists)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01015833

  Hide Study Locations
Locations
United States, Alabama
University of Alabama at Birmingham Cancer Center Completed
Birmingham, Alabama, United States, 35233
Providence Hospital Completed
Mobile, Alabama, United States, 36608
Southern Cancer Center PC-Providence Completed
Mobile, Alabama, United States, 36608
United States, Alaska
Alaska Regional Hospital Completed
Anchorage, Alaska, United States, 99508
Fairbanks Memorial Hospital Completed
Fairbanks, Alaska, United States, 99701
United States, Arkansas
Fowler Family Center for Cancer Care Completed
Jonesboro, Arkansas, United States, 72401
United States, California
Kaiser Anaheim Medical Center Completed
Anaheim, California, United States, 92807
Kaiser Permanente-Deer Valley Medical Center Completed
Antioch, California, United States, 94531
Kaiser Permanente Medical Group - Baldwin Park Completed
Baldwin Park, California, United States, 91706
Kaiser Foundation Hospital Completed
Bellflower, California, United States, 90706
Valley Medical Oncology Consultants-Castro Valley Completed
Castro Valley, California, United States, 94546
East Bay Radiation Oncology Center Completed
Castro Valley, California, United States, 94546
Epic Care-Dublin Completed
Dublin, California, United States, 94568
Bay Area Breast Surgeons Inc Completed
Emeryville, California, United States, 94608
Epic Care Partners in Cancer Care Completed
Emeryville, California, United States, 94608
Kaiser Permanente Hospital Completed
Fontana, California, United States, 92335
Kaiser Permanente, Fremont Completed
Fremont, California, United States, 94538
Valley Medical Oncology Consultants-Fremont Completed
Fremont, California, United States, 94538
University Oncology Associates Completed
Fresno, California, United States, 93701
Kaiser Permanente Completed
Fresno, California, United States, 93720
California Cancer Center - North Fresno Completed
Fresno, California, United States, 93720
Marin Cancer Care Inc Completed
Greenbrae, California, United States, 94904
Marin General Hospital Completed
Greenbrae, California, United States, 94904
Kaiser Permanente - Harbor City Completed
Harbor City, California, United States, 90710
Southern California Permanente Medical Group Completed
Irvine, California, United States, 92618
Kaiser Permanente Los Angeles Medical Center Completed
Los Angeles, California, United States, 90027
Kaiser Permanente-West Los Angeles Completed
Los Angeles, California, United States, 90034
Contra Costa Regional Medical Center Completed
Martinez, California, United States, 94553-3156
Kaiser Permanente-Modesto Completed
Modesto, California, United States, 95356
El Camino Hospital Completed
Mountain View, California, United States, 94040
Alta Bates Summit Medical Center - Summit Campus Completed
Oakland, California, United States, 94609
Bay Area Tumor Institute Completed
Oakland, California, United States, 94609
Highland General Hospital Completed
Oakland, California, United States, 94602
Kaiser Permanente-Oakland Completed
Oakland, California, United States, 94611
Larry G Strieff MD Medical Corporation Completed
Oakland, California, United States, 94609
Tom K Lee Inc Completed
Oakland, California, United States, 94609
Saint Joseph Hospital - Orange Completed
Orange, California, United States, 92868
UC Irvine Health/Chao Family Comprehensive Cancer Center Completed
Orange, California, United States, 92868
Kaiser Permanente - Panorama City Completed
Panorama City, California, United States, 91402
Palchak David MD Completed
Pismo Beach, California, United States, 93449
East Bay Medical Oncology Hematology Medical Associates Inc-Pleasant Hill Recruiting
Pleasant Hill, California, United States, 94523
Contact: James H. Feusner    510-450-7600      
Principal Investigator: James H. Feusner         
Kaiser Permanente-Redwood City Completed
Redwood City, California, United States, 94063
Kaiser Permanente-Richmond Completed
Richmond, California, United States, 94801
Kaiser Permanente Medical Center Completed
Riverside, California, United States, 92505
Kaiser Permanente-Roseville Completed
Roseville, California, United States, 95661
Kaiser Permanente - Sacramento Completed
Sacramento, California, United States, 95825
Kaiser Permanente-South Sacramento Completed
Sacramento, California, United States, 95823
Salinas Valley Memorial Withdrawn
Salinas, California, United States, 93901
Kaiser Permanente Completed
San Diego, California, United States, 92120
Kaiser Permanente at San Diego Completed
San Diego, California, United States, 92120
Kaiser Permanente-San Francisco Completed
San Francisco, California, United States, 94115
UCSF Medical Center-Mount Zion Withdrawn
San Francisco, California, United States, 94115
Kaiser Permanente-Santa Teresa-San Jose Completed
San Jose, California, United States, 95119
Kaiser Permanente San Leandro Completed
San Leandro, California, United States, 94577
Kaiser Permanente Health Care Completed
San Marcos, California, United States, 92069
Doctors Medical Center- JC Robinson Regional Cancer Center Completed
San Pablo, California, United States, 94806
Kaiser Permanente-San Rafael Completed
San Rafael, California, United States, 94903
Kaiser Permanente Medical Center - Santa Clara Completed
Santa Clara, California, United States, 95051
Kaiser Permanente-Santa Rosa Completed
Santa Rosa, California, United States, 95403
Kaiser Permanente-South San Francisco Completed
South San Francisco, California, United States, 94080
Kaiser Permanente-Stockton Completed
Stockton, California, United States, 95210
Kaiser Permanente Medical Center-Vacaville Completed
Vacaville, California, United States, 95688
Kaiser Permanente-Vallejo Completed
Vallejo, California, United States, 94589
Kaiser Permanente-Walnut Creek Completed
Walnut Creek, California, United States, 94596
Presbyterian Intercommunity Hospital Completed
Whittier, California, United States, 90602
Kaiser Permanente Completed
Woodland Hills, California, United States, 91367
United States, Colorado
University of Colorado Cancer Center - Anschutz Cancer Pavilion Completed
Aurora, Colorado, United States, 80045
Kaiser Permanente-Franklin Completed
Denver, Colorado, United States, 80205
Valley View Hospital Cancer Center Completed
Glenwood Springs, Colorado, United States, 81601
Saint Mary's Hospital and Regional Medical Center Completed
Grand Junction, Colorado, United States, 81502
Kaiser Permanente-Rock Creek Completed
Lafayette, Colorado, United States, 80026
Kaiser Permanente-Lone Tree Completed
Lone Tree, Colorado, United States, 80124
Montrose Memorial Hospital Withdrawn
Montrose, Colorado, United States, 81401
United States, Connecticut
Saint Francis Hospital and Medical Center Completed
Hartford, Connecticut, United States, 06105
Middlesex Hospital Completed
Middletown, Connecticut, United States, 06457
Yale University Completed
New Haven, Connecticut, United States, 06520
United States, Delaware
Beebe Medical Center Completed
Lewes, Delaware, United States, 19958
Christiana Care Health System-Christiana Hospital Completed
Newark, Delaware, United States, 19718
Christiana Gynecologic Oncology LLC Completed
Newark, Delaware, United States, 19713
Delaware Clinical and Laboratory Physicians PA Completed
Newark, Delaware, United States, 19713
Regional Hematology and Oncology PA Completed
Newark, Delaware, United States, 19713
Medical Oncology Hematology Consultants PA Completed
Newark, Delaware, United States, 19713
Helen F Graham Cancer Center Completed
Newark, Delaware, United States, 19713
Beebe Health Campus Completed
Rehoboth Beach, Delaware, United States, 19971
Nanticoke Memorial Hospital Completed
Seaford, Delaware, United States, 19973
Christiana Care Health System-Wilmington Hospital Completed
Wilmington, Delaware, United States, 19801
United States, District of Columbia
Veterans Affairs Medical Center -Washington DC Recruiting
Washington, District of Columbia, United States, 20422
Contact: Steven H. Krasnow    877-328-2621      
Principal Investigator: Steven H. Krasnow         
MedStar Georgetown University Hospital Completed
Washington, District of Columbia, United States, 20007
United States, Florida
Florida Hospital Cancer Institute Altamonte Completed
Altamonte Springs, Florida, United States, 32701
Florida Hospital Kissimmee Completed
Kissimmee, Florida, United States, 34744
Lakeland Regional Cancer Center Completed
Lakeland, Florida, United States, 33805
Florida Hospital Orlando Completed
Orlando, Florida, United States, 32803
Florida Hospital East Orlando Completed
Orlando, Florida, United States, 32822
Sacred Heart Hospital Completed
Pensacola, Florida, United States, 32504
Sacred Heart Medical Oncology Group - Davis Highway Recruiting
Pensacola, Florida, United States, 32514
Contact: Dee McLeod    850-416-4611      
Principal Investigator: Dee McLeod         
Florida Hospital Cancer Institute Winter Park Completed
Winter Park, Florida, United States, 32792
United States, Georgia
Atlanta VA Medical Center Completed
Decatur, Georgia, United States, 30033
Medical Center of Central Georgia Completed
Macon, Georgia, United States, 31208
Low Country Cancer Care Associates PC Completed
Savannah, Georgia, United States, 31405
Memorial University Medical Center Completed
Savannah, Georgia, United States, 31404
Summit Cancer Care-Memorial Completed
Savannah, Georgia, United States, 31404
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Completed
Savannah, Georgia, United States, 31405
United States, Hawaii
Pali Momi Medical Center Completed
Aiea, Hawaii, United States, 96701
University of Hawaii Cancer Center Completed
Honolulu, Hawaii, United States, 96813
Kaiser Permanente Moanalua Medical Center Completed
Honolulu, Hawaii, United States, 96819
Oncare Hawaii Inc-Kuakini Completed
Honolulu, Hawaii, United States, 96817
Oncare Hawaii Inc-POB II Completed
Honolulu, Hawaii, United States, 96813
OnCare Hawaii-Liliha Completed
Honolulu, Hawaii, United States, 96817-3169
Queen's Medical Center Completed
Honolulu, Hawaii, United States, 96813
Straub Clinic and Hospital Completed
Honolulu, Hawaii, United States, 96813
The Cancer Center of Hawaii-Liliha Completed
Honolulu, Hawaii, United States, 96817
Kapiolani Medical Center for Women and Children Completed
Honolulu, Hawaii, United States, 96826
Maui Memorial Medical Center Completed
Wailuku, Hawaii, United States, 96793
Pacific Cancer Institute of Maui Completed
Wailuku, Hawaii, United States, 96793
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Completed
Boise, Idaho, United States, 83706
Saint Joseph Regional Medical Center Completed
Lewiston, Idaho, United States, 83501
United States, Illinois
Rush - Copley Medical Center Completed
Aurora, Illinois, United States, 60504
Illinois CancerCare-Bloomington Completed
Bloomington, Illinois, United States, 61704
Saint Joseph Medical Center Completed
Bloomington, Illinois, United States, 61701
Illinois CancerCare-Canton Completed
Canton, Illinois, United States, 61520
Memorial Hospital of Carbondale Completed
Carbondale, Illinois, United States, 62902
Illinois CancerCare-Carthage Completed
Carthage, Illinois, United States, 62321
Centralia Oncology Clinic Completed
Centralia, Illinois, United States, 62801
University of Illinois Completed
Chicago, Illinois, United States, 60612
Northwestern University Completed
Chicago, Illinois, United States, 60611
Saint Joseph Hospital Completed
Chicago, Illinois, United States, 60657
University of Chicago Comprehensive Cancer Center Completed
Chicago, Illinois, United States, 60637
Hematology and Oncology Associates Completed
Chicago, Illinois, United States, 60611
Carle on Vermilion Completed
Danville, Illinois, United States, 61832
Cancer Care Center of Decatur Completed
Decatur, Illinois, United States, 62526
Decatur Memorial Hospital Completed
Decatur, Illinois, United States, 62526
Crossroads Cancer Center Completed
Effingham, Illinois, United States, 62401
Carle Physician Group-Effingham Completed
Effingham, Illinois, United States, 62401
Illinois CancerCare-Eureka Completed
Eureka, Illinois, United States, 61530
Illinois CancerCare Galesburg Completed
Galesburg, Illinois, United States, 61401
Western Illinois Cancer Treatment Center Completed
Galesburg, Illinois, United States, 61401
Hematology Oncology Associates of Illinois-Highland Park Completed
Highland Park, Illinois, United States, 60035
Joliet Oncology-Hematology Associates Limited Completed
Joliet, Illinois, United States, 60435
Midwest Center for Hematology Oncology Completed
Joliet, Illinois, United States, 60432
Presence Saint Mary's Hospital Completed
Kankakee, Illinois, United States, 60901
Illinois CancerCare-Kewanee Clinic Completed
Kewanee, Illinois, United States, 61443
Adventist La Grange Memorial Hospital Withdrawn
La Grange, Illinois, United States, 60525
North Shore Hematology Oncology Completed
Libertyville, Illinois, United States, 60048
Illinois CancerCare-Macomb Completed
Macomb, Illinois, United States, 61455
Carle Physician Group-Mattoon/Charleston Completed
Mattoon, Illinois, United States, 61938
Good Samaritan Regional Health Center Completed
Mount Vernon, Illinois, United States, 62864
Illinois Cancer Specialists-Niles Completed
Niles, Illinois, United States, 60714
Advocate Christ Medical Center Withdrawn
Oak Lawn, Illinois, United States, 60453-2699
Illinois CancerCare-Ottawa Clinic Completed
Ottawa, Illinois, United States, 61350
Radiation Oncology of Northern Illinois Completed
Ottawa, Illinois, United States, 61350
Illinois CancerCare-Pekin Completed
Pekin, Illinois, United States, 61554
Pekin Cancer Treatment Center Completed
Pekin, Illinois, United States, 61554
Illinois CancerCare-Peoria Completed
Peoria, Illinois, United States, 61615
OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC Completed
Peoria, Illinois, United States, 61615-7827
OSF Saint Francis Medical Center Completed
Peoria, Illinois, United States, 61637
Methodist Medical Center of Illinois Completed
Peoria, Illinois, United States, 61603
Valley Radiation Oncology Completed
Peru, Illinois, United States, 61354
Illinois CancerCare-Peru Completed
Peru, Illinois, United States, 61354
Illinois CancerCare-Princeton Completed
Princeton, Illinois, United States, 61356
Swedish American Hospital Withdrawn
Rockford, Illinois, United States, 61104
SwedishAmerican Regional Cancer Center/ACT Completed
Rockford, Illinois, United States, 61114
Hematology Oncology Associates of Illinois - Skokie Completed
Skokie, Illinois, United States, 60076
Springfield Clinic Completed
Springfield, Illinois, United States, 62703
Central Illinois Hematology Oncology Center Completed
Springfield, Illinois, United States, 62702
Southern Illinois University Completed
Springfield, Illinois, United States, 62702
Memorial Medical Center Completed
Springfield, Illinois, United States, 62781-0001
Cancer Care Specialists of Illinois-Swansea Completed
Swansea, Illinois, United States, 62226
Carle Cancer Center Completed
Urbana, Illinois, United States, 61801
The Carle Foundation Hospital Completed
Urbana, Illinois, United States, 61801
Rush-Copley Healthcare Center Completed
Yorkville, Illinois, United States, 60560
United States, Indiana
Saint Francis Hospital and Health Centers Withdrawn
Beech Grove, Indiana, United States, 46107
Elkhart Clinic Completed
Elkhart, Indiana, United States, 46514-2098
Elkhart General Hospital Completed
Elkhart, Indiana, United States, 46515
Michiana Hematology Oncology PC-Elkhart Completed
Elkhart, Indiana, United States, 46514
Fort Wayne Medical Oncology and Hematology Inc-Parkview Withdrawn
Fort Wayne, Indiana, United States, 46845
Franciscan Saint Francis Health-Indianapolis Withdrawn
Indianapolis, Indiana, United States, 46237
Community Howard Regional Health Completed
Kokomo, Indiana, United States, 46904
IU Health La Porte Hospital Completed
La Porte, Indiana, United States, 46350
Franciscan Saint Anthony Health-Michigan City Completed
Michigan City, Indiana, United States, 46360
Woodland Cancer Care Center Completed
Michigan City, Indiana, United States, 46360
Cancer Care Partners LLC Completed
Mishawaka, Indiana, United States, 46545
Memorial Regional Cancer Center Day Road Completed
Mishawaka, Indiana, United States, 46544
Saint Joseph Regional Medical Center-Mishawaka Completed
Mishawaka, Indiana, United States, 46545
Michiana Hematology Oncology PC-Mishawaka Completed
Mishawaka, Indiana, United States, 46545
Michiana Hematology Oncology PC-Plymouth Completed
Plymouth, Indiana, United States, 46563
Reid Hospital and Health Care Services Withdrawn
Richmond, Indiana, United States, 47374
Memorial Hospital of South Bend Completed
South Bend, Indiana, United States, 46601
Michiana Hematology Oncology PC-South Bend Completed
South Bend, Indiana, United States, 46601
Northern Indiana Cancer Research Consortium CCOP Recruiting
South Bend, Indiana, United States, 46628
Contact: Rafat H. Ansari    574-234-5123      
Principal Investigator: Rafat H. Ansari         
South Bend Clinic Completed
South Bend, Indiana, United States, 46617
Michiana Hematology Oncology-PC Westville Completed
Westville, Indiana, United States, 46391
United States, Iowa
Mary Greeley Medical Center Completed
Ames, Iowa, United States, 50010
McFarland Clinic PC-William R Bliss Cancer Center Completed
Ames, Iowa, United States, 50010
Hematology Oncology Associates-Quad Cities Completed
Bettendorf, Iowa, United States, 52722
McFarland Clinic PC-Boone Completed
Boone, Iowa, United States, 50036
Medical Oncology and Hematology Associates-West Des Moines Completed
Clive, Iowa, United States, 50325
Mercy Cancer Center-West Lakes Completed
Clive, Iowa, United States, 50325
Alegent Health Mercy Hospital Completed
Council Bluffs, Iowa, United States, 51503
Mercy Medical Center - Des Moines Completed
Des Moines, Iowa, United States, 50314
Medical Oncology and Hematology Associates-Laurel Completed
Des Moines, Iowa, United States, 50314
McFarland Clinic PC-Trinity Cancer Center Completed
Fort Dodge, Iowa, United States, 50501
VA Medical Center - University of Iowa Completed
Iowa City, Iowa, United States, 52246
University of Iowa/Holden Comprehensive Cancer Center Withdrawn
Iowa City, Iowa, United States, 52242
McFarland Clinic PC-Jefferson Completed
Jefferson, Iowa, United States, 50129
McFarland Clinic PC-Marshalltown Completed
Marshalltown, Iowa, United States, 50158
Ottumwa Regional Health Center Completed
Ottumwa, Iowa, United States, 52501
Mercy Medical Center-Sioux City Completed
Sioux City, Iowa, United States, 51104
Saint Luke's Regional Medical Center Completed
Sioux City, Iowa, United States, 51104
Siouxland Hematology Oncology Associates Completed
Sioux City, Iowa, United States, 51101
Mercy Medical Center-West Lakes Completed
West Des Moines, Iowa, United States, 50266
United States, Kansas
Cancer Center of Kansas - Chanute Completed
Chanute, Kansas, United States, 66720
Cancer Center of Kansas - Dodge City Completed
Dodge City, Kansas, United States, 67801
Cancer Center of Kansas - El Dorado Completed
El Dorado, Kansas, United States, 67042
Cancer Center of Kansas - Fort Scott Completed
Fort Scott, Kansas, United States, 66701
Cancer Center of Kansas-Independence Completed
Independence, Kansas, United States, 67301
Providence Medical Center Completed
Kansas City, Kansas, United States, 66112
Cancer Center of Kansas-Kingman Completed
Kingman, Kansas, United States, 67068
Lawrence Memorial Hospital Completed
Lawrence, Kansas, United States, 66044
Cancer Center of Kansas-Liberal Completed
Liberal, Kansas, United States, 67901
Cancer Center of Kansas-Manhattan Completed
Manhattan, Kansas, United States, 66502
Cancer Center of Kansas - McPherson Completed
McPherson, Kansas, United States, 67460
Cancer Center of Kansas - Newton Completed
Newton, Kansas, United States, 67114
Menorah Medical Center Completed
Overland Park, Kansas, United States, 66209
Saint Luke's South Hospital Completed
Overland Park, Kansas, United States, 66213
Cancer Center of Kansas - Parsons Completed
Parsons, Kansas, United States, 67357
Kansas City CCOP Terminated
Prairie Village, Kansas, United States, 66208
Cancer Center of Kansas - Pratt Completed
Pratt, Kansas, United States, 67124
Cancer Center of Kansas - Salina Completed
Salina, Kansas, United States, 67401
Shawnee Mission Medical Center Completed
Shawnee Mission, Kansas, United States, 66204
Stormont-Vail Regional Health Center Completed
Topeka, Kansas, United States, 66604
Cancer Center of Kansas - Wellington Completed
Wellington, Kansas, United States, 67152
Associates In Womens Health Completed
Wichita, Kansas, United States, 67208
Cancer Center of Kansas - Main Office Completed
Wichita, Kansas, United States, 67214
Cancer Center of Kansas-Wichita Medical Arts Tower Completed
Wichita, Kansas, United States, 67208
Wichita CCOP Terminated
Wichita, Kansas, United States, 67214
Wesley Medical Center Completed
Wichita, Kansas, United States, 67214
Via Christi Regional Medical Center Completed
Wichita, Kansas, United States, 67214
Cancer Center of Kansas - Winfield Completed
Winfield, Kansas, United States, 67156
United States, Kentucky
Flaget Memorial Hospital Completed
Bardstown, Kentucky, United States, 40004
Commonwealth Cancer Center-Corbin Completed
Corbin, Kentucky, United States, 40701
Saint Joseph Hospital East Completed
Lexington, Kentucky, United States, 40509
Saint Joseph Radiation Oncology Resource Center Completed
Lexington, Kentucky, United States, 40504
University of Kentucky/Markey Cancer Center Withdrawn
Lexington, Kentucky, United States, 40536
Doctors Carrol, Sheth, Raghavan Completed
Louisville, Kentucky, United States, 40215
Jewish Hospital Completed
Louisville, Kentucky, United States, 40202
Jewish Hospital Medical Center Northeast Completed
Louisville, Kentucky, United States, 40245
Saints Mary and Elizabeth Hospital Completed
Louisville, Kentucky, United States, 40215
Jewish Hospital Medical Center South Completed
Shepherdsville, Kentucky, United States, 40165
United States, Louisiana
Medical Oncology LLC Completed
Baton Rouge, Louisiana, United States, 70809
Hematology/Oncology Clinic LLP Completed
Baton Rouge, Louisiana, United States, 70809
Louisiana Hematology Oncology Associates LLC Completed
Baton Rouge, Louisiana, United States, 70809
LSU Health Baton Rouge-North Clinic Completed
Baton Rouge, Louisiana, United States, 70805
Mary Bird Perkins Cancer Center Completed
Baton Rouge, Louisiana, United States, 70809
Baton Rouge General Medical Center Completed
Baton Rouge, Louisiana, United States, 70806
Ochsner Health Center-Summa Completed
Baton Rouge, Louisiana, United States, 70809
Ochsner Health Center-Covington Completed
Covington, Louisiana, United States, 70433
Mary Bird Perkins Cancer Center/Terrebonne General Medical Center Completed
Houma, Louisiana, United States, 70360
West Jefferson Medical Center Completed
Marrero, Louisiana, United States, 70072
Robert Veith MD LLC Completed
Metairie, Louisiana, United States, 70006
Interim LSU Public Hospital Completed
New Orleans, Louisiana, United States, 70112
Louisiana State University Health Science Center Completed
New Orleans, Louisiana, United States, 70112
Ochsner Medical Center Jefferson Completed
New Orleans, Louisiana, United States, 70121
Tulane University Health Sciences Center Completed
New Orleans, Louisiana, United States, 70112
Louisiana State University Health Sciences Center Shreveport Recruiting
Shreveport, Louisiana, United States, 71103
Contact: Ghassan K. Abou-Alfa    212-639-7202    abou-alg@mskcc.org   
Principal Investigator: Ghassan K. Abou-Alfa         
United States, Maine
York Hospital Completed
York, Maine, United States, 03909
United States, Maryland
Greater Baltimore Medical Center Completed
Baltimore, Maryland, United States, 21204
Johns Hopkins University/Sidney Kimmel Cancer Center Completed
Baltimore, Maryland, United States, 21287
Saint Agnes Hospital Completed
Baltimore, Maryland, United States, 21229
Sinai Hospital of Baltimore Completed
Baltimore, Maryland, United States, 21215
University of Maryland/Greenebaum Cancer Center Withdrawn
Baltimore, Maryland, United States, 21201
Walter Reed National Military Medical Center Withdrawn
Bethesda, Maryland, United States, 20889-5600
Union Hospital of Cecil County Completed
Elkton MD, Maryland, United States, 21921
Northwest Hospital Center Completed
Randallstown, Maryland, United States, 21133
United States, Massachusetts
Boston Medical Center Completed
Boston, Massachusetts, United States, 02118
United States, Michigan
Bixby Medical Center Withdrawn
Adrian, Michigan, United States, 49221
Hickman Cancer Center Withdrawn
Adrian, Michigan, United States, 49221
Saint Joseph Mercy Hospital Completed
Ann Arbor, Michigan, United States, 48106-0995
Michigan Cancer Research Consortium CCOP Terminated
Ann Arbor, Michigan, United States, 48106
Oakwood Hospital and Medical Center Completed
Dearborn, Michigan, United States, 48124
Saint John Hospital and Medical Center Completed
Detroit, Michigan, United States, 48236
Green Bay Oncology - Escanaba Completed
Escanaba, Michigan, United States, 49431
Genesys Hurley Cancer Institute Completed
Flint, Michigan, United States, 48503
Genesys Regional Medical Center-West Flint Campus Completed
Flint, Michigan, United States, 48532
Hurley Medical Center Completed
Flint, Michigan, United States, 48502
Genesys Regional Medical Center Completed
Grand Blanc, Michigan, United States, 48439
Green Bay Oncology - Iron Mountain Completed
Iron Mountain, Michigan, United States, 49801
Allegiance Health Completed
Jackson, Michigan, United States, 49201
Borgess Medical Center Completed
Kalamazoo, Michigan, United States, 49001
Bronson Methodist Hospital Completed
Kalamazoo, Michigan, United States, 49007
West Michigan Cancer Center Completed
Kalamazoo, Michigan, United States, 49007
Sparrow Hospital Completed
Lansing, Michigan, United States, 48912
Saint Mary Mercy Hospital Completed
Livonia, Michigan, United States, 48154
Community Cancer Center of Monroe Withdrawn
Monroe, Michigan, United States, 48162
Mercy Memorial Hospital Withdrawn
Monroe, Michigan, United States, 48162
Lakeland Community Hospital Completed
Niles, Michigan, United States, 49120
Michiana Hematology Oncology PC-Niles Terminated
Niles, Michigan, United States, 49120
Saint Joseph Mercy Oakland Completed
Pontiac, Michigan, United States, 48341
Saint Joseph Mercy Port Huron Completed
Port Huron, Michigan, United States, 48060
Saint Mary's of Michigan Completed
Saginaw, Michigan, United States, 48601
Marie Yeager Cancer Center Withdrawn
Saint Joseph, Michigan, United States, 49085
Providence Hospital Withdrawn
Southfield, Michigan, United States, 48075
Lakeland Hospital Completed
St. Joseph, Michigan, United States, 49085
Saint John Macomb-Oakland Hospital Completed
Warren, Michigan, United States, 48093
United States, Minnesota
Essentia Health Saint Joseph's Medical Center Completed
Brainerd, Minnesota, United States, 56401
Fairview Ridges Hospital Completed
Burnsville, Minnesota, United States, 55337
Mercy Hospital Completed
Coon Rapids, Minnesota, United States, 55433
Essentia Health Cancer Center Completed
Duluth, Minnesota, United States, 55805
Essentia Health Saint Mary's Medical Center Completed
Duluth, Minnesota, United States, 55805
Miller-Dwan Hospital Completed
Duluth, Minnesota, United States, 55805
Fairview-Southdale Hospital Completed
Edina, Minnesota, United States, 55435
Unity Hospital Completed
Fridley, Minnesota, United States, 55432
Hutchinson Area Health Care Completed
Hutchinson, Minnesota, United States, 55350
Minnesota Oncology Hematology PA-Maplewood Completed
Maplewood, Minnesota, United States, 55109
Saint John's Hospital - Healtheast Completed
Maplewood, Minnesota, United States, 55109
Minneapolis Veterans Medical Center Completed
Minneapolis, Minnesota, United States, 55417
Health Partners Inc Completed
Minneapolis, Minnesota, United States, 55454
Hennepin County Medical Center Completed
Minneapolis, Minnesota, United States, 55415
Abbott-Northwestern Hospital Completed
Minneapolis, Minnesota, United States, 55407
New Ulm Medical Center Completed
New Ulm, Minnesota, United States, 56073
North Memorial Medical Health Center Completed
Robbinsdale, Minnesota, United States, 55422
Park Nicollet Clinic - Saint Louis Park Completed
Saint Louis Park, Minnesota, United States, 55416
Metro-Minnesota NCI Community Oncology Research Program Terminated
Saint Louis Park, Minnesota, United States, 55416
Regions Hospital Completed
Saint Paul, Minnesota, United States, 55101
United Hospital Completed
Saint Paul, Minnesota, United States, 55102
Saint Francis Regional Medical Center Completed
Shakopee, Minnesota, United States, 55379
Lakeview Hospital Completed
Stillwater, Minnesota, United States, 55082
Ridgeview Medical Center Completed
Waconia, Minnesota, United States, 55387
Rice Memorial Hospital Completed
Willmar, Minnesota, United States, 56201
Minnesota Oncology and Hematology PA-Woodbury Completed
Woodbury, Minnesota, United States, 55125
United States, Mississippi
Forest General Hospital Completed
Hattiesburg, Mississippi, United States, 39404
Hattiesburg Clinic Completed
Hattiesburg, Mississippi, United States, 39401
University of Mississippi Medical Center Completed
Jackson, Mississippi, United States, 39216
United States, Missouri
Central Care Cancer Center-Carrie J Babb Cancer Center Completed
Bolivar, Missouri, United States, 65613
Parkland Health Center-Bonne Terre Completed
Bonne Terre, Missouri, United States, 63628
CoxHealth Cancer Center Completed
Branson, Missouri, United States, 65616
Saint Francis Medical Center Completed
Cape Girardeau, Missouri, United States, 63703
Southeast Cancer Center Completed
Cape Girardeau, Missouri, United States, 63703
University of Missouri - Ellis Fischel Completed
Columbia, Missouri, United States, 65212
Veterans Administration Completed
Columbia, Missouri, United States, 65201
Centerpoint Medical Center LLC Completed
Independence, Missouri, United States, 64057
Capital Region Medical Center-Goldschmidt Cancer Center Completed
Jefferson City, Missouri, United States, 65109
Freeman Health System Completed
Joplin, Missouri, United States, 64804
Mercy Hospital-Joplin Completed
Joplin, Missouri, United States, 64804
North Kansas City Hospital Completed
Kansas City, Missouri, United States, 64116
Truman Medical Center Completed
Kansas City, Missouri, United States, 64108
Research Medical Center Completed
Kansas City, Missouri, United States, 64132
Saint Joseph Health Center Completed
Kansas City, Missouri, United States, 64114
Saint Luke's Cancer Institute Terminated
Kansas City, Missouri, United States, 64111
Saint Luke's Hospital of Kansas City Completed
Kansas City, Missouri, United States, 64111
Heartland Hematology and Oncology Associates Incorporated Completed
Kansas City, Missouri, United States, 64118
Saint Luke's East - Lee's Summit Completed
Lee's Summit, Missouri, United States, 64086
Liberty Hospital Withdrawn
Liberty, Missouri, United States, 64068
Liberty Radiation Oncology Center Completed
Liberty, Missouri, United States, 64068
Phelps County Regional Medical Center Completed
Rolla, Missouri, United States, 65401
Saint John's Clinic-Rolla-Cancer and Hematology Completed
Rolla, Missouri, United States, 65401
Heartland Regional Medical Center Completed
Saint Joseph, Missouri, United States, 64506
Saint Joseph Oncology Inc Completed
Saint Joseph, Missouri, United States, 64507
Comprehensive Cancer Care PC Completed
Saint Louis, Missouri, United States, 63141
Missouri Baptist Medical Center Completed
Saint Louis, Missouri, United States, 63131
Saint John's Mercy Medical Center Completed
Saint Louis, Missouri, United States, 63141
Saint Louis Cancer and Breast Institute-South City Completed
Saint Louis, Missouri, United States, 63109
Washington University School of Medicine Completed
Saint Louis, Missouri, United States, 63110
Center for Cancer Care and Research Completed
Saint Louis, Missouri, United States, 63141
Sainte Genevieve County Memorial Hospital Completed
Sainte Genevieve, Missouri, United States, 63670
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Terminated
Springfield, Missouri, United States, 65804
Mercy Hospital Springfield Completed
Springfield, Missouri, United States, 65804
CoxHealth South Hospital Completed
Springfield, Missouri, United States, 65807
Missouri Baptist Sullivan Hospital Completed
Sullivan, Missouri, United States, 63080
Missouri Baptist Outpatient Center-Sunset Hills Completed
Sunset Hills, Missouri, United States, 63127
United States, Nebraska
CHI Health Saint Francis Completed
Grand Island, Nebraska, United States, 68803
Heartland Hematology and Oncology Completed
Kearney, Nebraska, United States, 68845
CHI Health Good Samaritan Completed
Kearney, Nebraska, United States, 68847
Saint Elizabeth Regional Medical Center Completed
Lincoln, Nebraska, United States, 68510
Great Plains Regional Medical Center Completed
North Platte, Nebraska, United States, 69103
Alegent Health Bergan Mercy Medical Center Completed
Omaha, Nebraska, United States, 68124
Alegent Health Immanuel Medical Center Completed
Omaha, Nebraska, United States, 68122
Alegent Health Lakeside Hospital Completed
Omaha, Nebraska, United States, 68130
Creighton University Medical Center Completed
Omaha, Nebraska, United States, 68131
Hemotology and Oncology Consultants PC Completed
Omaha, Nebraska, United States, 68122
Nebraska Methodist Hospital Completed
Omaha, Nebraska, United States, 68114
University of Nebraska Medical Center Completed
Omaha, Nebraska, United States, 68198
Midlands Community Hospital Completed
Papillion, Nebraska, United States, 68046
United States, Nevada
21st Century Oncology - Henderson Completed
Henderson, Nevada, United States, 89074
Cancer and Blood Specialists-Henderson Completed
Henderson, Nevada, United States, 89052
Comprehensive Cancer Centers of Nevada - Henderson Completed
Henderson, Nevada, United States, 89052
Comprehensive Cancer Centers of Nevada-Southeast Henderson Completed
Henderson, Nevada, United States, 89074
Las Vegas Cancer Center-Henderson Completed
Henderson, Nevada, United States, 89052
HealthCare Partners Medical Group Oncology/Hematology-San Martin Completed
Las Vegas, Nevada, United States, 89113
21st Century Oncology - Vegas Sunrise Completed
Las Vegas, Nevada, United States, 89109
21st Century Oncology - Vegas Tenaya Completed
Las Vegas, Nevada, United States, 89182
Cancer and Blood Specialists-Fort Apache Completed
Las Vegas, Nevada, United States, 89148
Cancer and Blood Specialists-Shadow Completed
Las Vegas, Nevada, United States, 89106
Cancer and Blood Specialists-Tenaya Completed
Las Vegas, Nevada, United States, 89128
Cancer Therapy and Integrative Medicine Completed
Las Vegas, Nevada, United States, 89121
Children's Specialty Center of Nevada II Active, not recruiting
Las Vegas, Nevada, United States, 89109
Comprehensive Cancer Centers of Nevada Completed
Las Vegas, Nevada, United States, 89148
Comprehensive Cancer Centers of Nevada - Central Valley Completed
Las Vegas, Nevada, United States, 89169
Comprehensive Cancer Centers of Nevada - Northwest Completed
Las Vegas, Nevada, United States, 89128
Comprehensive Cancer Centers of Nevada-Summerlin Completed
Las Vegas, Nevada, United States, 89144
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Completed
Las Vegas, Nevada, United States, 89149
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Completed
Las Vegas, Nevada, United States, 89109
University Medical Center of Southern Nevada Completed
Las Vegas, Nevada, United States, 89102
HealthCare Partners Medical Group Oncology/Hematology-Tenaya Completed
Las Vegas, Nevada, United States, 89128
Las Vegas Cancer Center-Medical Center Completed
Las Vegas, Nevada, United States, 89148-2405
Nevada Cancer Research Foundation CCOP Recruiting
Las Vegas, Nevada, United States, 89106
Contact: John A. Ellerton    702-384-0013      
Principal Investigator: John A. Ellerton         
Radiation Oncology Centers of Nevada Central Completed
Las Vegas, Nevada, United States, 89106
21st Century Oncology - Fort Apache Completed
Las Vegas, Nevada, United States, 89148
Summerlin Hospital Medical Center Completed
Las Vegas, Nevada, United States, 89144
Radiation Oncology Centers of Nevada Southeast Completed
Las Vegas, Nevada, United States, 89119
Saint Mary's Regional Medical Center Completed
Reno, Nevada, United States, 89503
Radiation Oncology Associates Completed
Reno, Nevada, United States, 89509
Reno Oncology Consultants Completed
Reno, Nevada, United States, 89519
Renown Regional Medical Center Completed
Reno, Nevada, United States, 89502
Alpine Hematology-Oncology Completed
Reno, Nevada, United States, 89503
United States, New Hampshire
Dartmouth Hitchcock Medical Center Withdrawn
Lebanon, New Hampshire, United States, 03756
United States, New Jersey
Cooper Hospital University Medical Center Completed
Camden, New Jersey, United States, 08103
Veterans Adminstration New Jersey Health Care System Completed
East Orange, New Jersey, United States, 07018-1095
UMDNJ - New Jersey Medical School Completed
Newark, New Jersey, United States, 07103
Inspira Medical Center Vineland Completed
Vineland, New Jersey, United States, 08360
Inspira Medical Center Woodbury Completed
Woodbury, New Jersey, United States, 08096
United States, New Mexico
University of New Mexico Completed
Albuquerque, New Mexico, United States, 87106
Memorial Medical Center - Las Cruces Completed
Las Cruces, New Mexico, United States, 88011
United States, New York
Hematology Oncology Associates of Central New York-Auburn Completed
Auburn, New York, United States, 13021
Albert Einstein College of Medicine Completed
Bronx, New York, United States, 10461
Bronx Veterans Administration Medical Center Completed
Bronx, New York, United States, 10468
Montefiore Medical Center - Moses Campus Completed
Bronx, New York, United States, 10467-2490
Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus Completed
Brooklyn, New York, United States, 11209
Veterans Affairs Western New York Health Care System-Buffalo Completed
Buffalo, New York, United States, 14215
Hematology Oncology Associates of Central New York-East Syracuse Completed
East Syracuse, New York, United States, 13057
Glens Falls Hospital Completed
Glens Falls, New York, United States, 12801
Hematology Oncology Associates of Central New York-Liverpool Completed
Liverpool, New York, United States, 13088
North Shore University Hospital Completed
Manhasset, New York, United States, 11030
North Shore-LIJ Health System CCOP Terminated
Manhasset, New York, United States, 11030
Orange Regional Medical Center Completed
Middletown, New York, United States, 10940
North Shore-LIJ Health System/Center for Advanced Medicine Completed
New Hyde Park, New York, United States, 11040
Long Island Jewish Medical Center Completed
New Hyde Park, New York, United States, 11040
Weill Medical College of Cornell University Completed
New York, New York, United States, 10065
Beth Israel Medical Center Recruiting
New York, New York, United States, 10003
Contact: Peter S. Kozuch    212-844-6286      
Principal Investigator: Peter S. Kozuch         
Columbia University Medical Center Completed
New York, New York, United States, 10032
Saint Luke's Roosevelt Hospital Center - Saint Luke's Division Recruiting
New York, New York, United States, 10025
Contact: Peter S. Kozuch    212-844-6286      
Principal Investigator: Peter S. Kozuch         
Memorial Sloan-Kettering Cancer Center Completed
New York, New York, United States, 10065
University of Rochester Completed
Rochester, New York, United States, 14642
Hematology Oncology Associates of Central New York-Rome Completed
Rome, New York, United States, 13440
Stony Brook University Medical Center Completed
Stony Brook, New York, United States, 11794
Hematology Oncology Associates of Central New York-Onondaga Hill Completed
Syracuse, New York, United States, 13215
State University of New York Upstate Medical University Completed
Syracuse, New York, United States, 13210
New York Medical College Completed
Valhalla, New York, United States, 10595
United States, North Carolina
Mountain Radiation Oncology Active, not recruiting
Asheville, North Carolina, United States, 28801
Cancer Care of Western North Carolina Completed
Asheville, North Carolina, United States, 28801
Hope Women's Cancer Centers-Asheville Active, not recruiting
Asheville, North Carolina, United States, 28816
Mission Hospital-Memorial Campus Completed
Asheville, North Carolina, United States, 28801
Asheville Hematology-Oncology Associates Completed
Asheville, North Carolina, United States, 28803
Transylvania Regional Hospital Terminated
Brevard, North Carolina, United States, 28612
Novant Health Presbyterian Medical Center Completed
Charlotte, North Carolina, United States, 28204
Sampson Radiation Oncology Completed
Clinton, North Carolina, United States, 28328
Southeastern Medical Oncology Center-Clinton Completed
Clinton, North Carolina, United States, 28328
Angel Medical Center Terminated
Franklin, North Carolina, United States, 28744
Southeastern Medical Oncology Center-Goldsboro Completed
Goldsboro, North Carolina, United States, 27534
Wayne Memorial Hospital Completed
Goldsboro, North Carolina, United States, 27534
Wayne Radiation Oncology Completed
Goldsboro, North Carolina, United States, 27534
Park Ridge Hospital Breast Health Center Completed
Hendersonville, North Carolina, United States, 28792
Onslow Memorial Hospital Completed
Jacksonville, North Carolina, United States, 28546
Southeastern Medical Oncology Center-Jacksonville Completed
Jacksonville, North Carolina, United States, 28546
Kinston Medical Specialists PA Completed
Kinston, North Carolina, United States, 28501
McDowell Hospital Terminated
Marion, North Carolina, United States, 28754
Rutherford Hospital Withdrawn
Rutherfordton, North Carolina, United States, 28139
Blue Ridge Regional Hospital Terminated
Spruce Pine, North Carolina, United States, 28777
Iredell Memorial Hospital Completed
Statesville, North Carolina, United States, 28677
Southeastern Medical Oncology Center-Wilson Completed
Wilson, North Carolina, United States, 27893
Wake Forest University Health Sciences Completed
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Mid Dakota Clinic Completed
Bismarck, North Dakota, United States, 58501
Saint Alexius Medical Center Completed
Bismarck, North Dakota, United States, 58501
Sanford Bismarck Medical Center Withdrawn
Bismarck, North Dakota, United States, 58501
Essentia Health Cancer Center-South University Clinic Completed
Fargo, North Dakota, United States, 58103
Trinity Cancer Care Center Completed
Minot, North Dakota, United States, 58701
United States, Ohio
Summa Akron City Hospital/Cooper Cancer Center Completed
Akron, Ohio, United States, 44304
Summa Barberton Hospital Completed
Barberton, Ohio, United States, 44203
Mary Rutan Hospital Completed
Bellefontaine, Ohio, United States, 43311
Strecker Cancer Center-Belpre Completed
Belpre, Ohio, United States, 45714
Toledo Clinic Cancer Centers-Bowling Green Withdrawn
Bowling Green, Ohio, United States, 43402
Aultman Health Foundation Completed
Canton, Ohio, United States, 44710
Adena Regional Medical Center Completed
Chillicothe, Ohio, United States, 45601
Bethesda North Hospital Completed
Cincinnati, Ohio, United States, 45242
Good Samaritan Hospital - Cincinnati Completed
Cincinnati, Ohio, United States, 45220
TriHealth Cancer Institute-Anderson Completed
Cincinnati, Ohio, United States, 45255
TriHealth Cancer Institute-Westside Completed
Cincinnati, Ohio, United States, 45247
MetroHealth Medical Center Completed
Cleveland, Ohio, United States, 44109
North Coast Cancer Care-Clyde Completed
Clyde, Ohio, United States, 43410
Mount Carmel East Hospital Completed
Columbus, Ohio, United States, 43213
Columbus Oncology and Hematology Associates Inc Completed
Columbus, Ohio, United States, 43214
Doctors Hospital Completed
Columbus, Ohio, United States, 43228
Grant Medical Center Completed
Columbus, Ohio, United States, 43215
Mount Carmel Health Center West Completed
Columbus, Ohio, United States, 43222
Ohio State University Comprehensive Cancer Center Recruiting
Columbus, Ohio, United States, 43210
Contact: Ghassan K. Abou-Alfa    212-639-7202    abou-alg@mskcc.org   
Principal Investigator: Ghassan K. Abou-Alfa         
Riverside Methodist Hospital Completed
Columbus, Ohio, United States, 43214
The Mark H Zangmeister Center Completed
Columbus, Ohio, United States, 43219
Columbus CCOP Terminated
Columbus, Ohio, United States, 43215
Veteran Affairs Medical Center Completed
Dayton, Ohio, United States, 45428
Dayton CCOP Withdrawn
Dayton, Ohio, United States, 45420
Good Samaritan Hospital - Dayton Withdrawn
Dayton, Ohio, United States, 45406
Miami Valley Hospital Withdrawn
Dayton, Ohio, United States, 45409
Samaritan North Health Center Withdrawn
Dayton, Ohio, United States, 45415
Grandview Hospital Withdrawn
Dayton, Ohio, United States, 45405
Delaware Health Center-Grady Cancer Center Completed
Delaware, Ohio, United States, 43015
Delaware Radiation Oncology Completed
Delaware, Ohio, United States, 43015
Grady Memorial Hospital Completed
Delaware, Ohio, United States, 43015
Hematology Oncology Center Incorporated Completed
Elyria, Ohio, United States, 44035
Mercy Cancer Center-Elyria Completed
Elyria, Ohio, United States, 44035
Blanchard Valley Hospital Withdrawn
Findlay, Ohio, United States, 45840
Atrium Medical Center-Middletown Regional Hospital Withdrawn
Franklin, Ohio, United States, 45005-1066
Wayne Hospital Withdrawn
Greenville, Ohio, United States, 45331
Kettering Medical Center Withdrawn
Kettering, Ohio, United States, 45429
Fairfield Medical Center Completed
Lancaster, Ohio, United States, 43130
Lancaster Radiation Oncology Completed
Lancaster, Ohio, United States, 43130
Saint Rita's Medical Center Completed
Lima, Ohio, United States, 45801
Lima Memorial Hospital Withdrawn
Lima, Ohio, United States, 45804
Marietta Memorial Hospital Completed
Marietta, Ohio, United States, 45750
Saint Luke's Hospital Completed
Maumee, Ohio, United States, 43537
Toledo Clinic Cancer Centers-Maumee Withdrawn
Maumee, Ohio, United States, 43537
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center Withdrawn
Maumee, Ohio, United States, 43537
Knox Community Hospital Completed
Mount Vernon, Ohio, United States, 43050
Licking Memorial Hospital Completed
Newark, Ohio, United States, 43055
Newark Radiation Oncology Completed
Newark, Ohio, United States, 43055
Fisher-Titus Medical Center Completed
Norwalk, Ohio, United States, 44857
Saint Charles Hospital Withdrawn
Oregon, Ohio, United States, 43616
Toledo Clinic Cancer Centers-Oregon Withdrawn
Oregon, Ohio, United States, 43616
Southern Ohio Medical Center Completed
Portsmouth, Ohio, United States, 45662
North Coast Cancer Care Completed
Sandusky, Ohio, United States, 44870
Springfield Regional Medical Center Completed
Springfield, Ohio, United States, 45505
Flower Hospital Withdrawn
Sylvania, Ohio, United States, 43560
Mercy Hospital of Tiffin Withdrawn
Tiffin, Ohio, United States, 44883
Mercy Saint Anne Hospital Withdrawn
Toledo, Ohio, United States, 43623
Saint Vincent Mercy Medical Center Withdrawn
Toledo, Ohio, United States, 43608
The Toledo Hospital/Toledo Children's Hospital Withdrawn
Toledo, Ohio, United States, 43606
University of Toledo Withdrawn
Toledo, Ohio, United States, 43614
Toledo Community Hospital Oncology Program CCOP Withdrawn
Toledo, Ohio, United States, 43617
Toledo Clinic Cancer Centers-Toledo Withdrawn
Toledo, Ohio, United States, 43623
Upper Valley Medical Center Withdrawn
Troy, Ohio, United States, 45373
Fulton County Health Center Withdrawn
Wauseon, Ohio, United States, 43567
Saint Ann's Hospital Completed
Westerville, Ohio, United States, 43081
Clinton Memorial Hospital Completed
Wilmington, Ohio, United States, 45177
Greene Memorial Hospital Withdrawn
Xenia, Ohio, United States, 45385
Genesis HealthCare System Completed
Zanesville, Ohio, United States, 43701
United States, Oklahoma
Cancer Care Associates-Norman Withdrawn
Norman, Oklahoma, United States, 73071
University of Oklahoma Health Sciences Center Completed
Oklahoma City, Oklahoma, United States, 73104
Mercy Physicians of Oklahoma-Lakeside Completed
Oklahoma City, Oklahoma, United States, 73120
Mercy Hospital Oklahoma City Withdrawn
Oklahoma City, Oklahoma, United States, 73120
Tulsa Cancer Institute Completed
Tulsa, Oklahoma, United States, 74146
United States, Oregon
Kaiser Permanente Completed
Portland, Oregon, United States, 97227
United States, Pennsylvania
Abington Memorial Hospital Completed
Abington, Pennsylvania, United States, 19001
Lehigh Valley Hospital-Cedar Crest Recruiting
Allentown, Pennsylvania, United States, 18103
Contact: Eliot L. Friedman    610-402-2273      
Principal Investigator: Eliot L. Friedman         
Butler Memorial Hospital Completed
Butler, Pennsylvania, United States, 16001
VA Pittsburgh Healthcare System Completed
Pittsburgh, Pennsylvania, United States, 15240
Guthrie Medical Group PC-Robert Packer Hospital Completed
Sayre, Pennsylvania, United States, 18840
Reading Hospital Completed
West Reading, Pennsylvania, United States, 19611
United States, Rhode Island
Roger Williams Hospital Recruiting
Providence, Rhode Island, United States, 02908
Contact: Ponnandai S. Somasundar    401-456-2268    rdavies@rwmc.org   
Principal Investigator: Ponnandai S. Somasundar         
United States, South Carolina
AnMed Health Cancer Center Completed
Anderson, South Carolina, United States, 29621
AnMed Health Hospital Recruiting
Anderson, South Carolina, United States, 29621
Contact: Charles E. Bowers    800-486-5941      
Principal Investigator: Charles E. Bowers         
Greenville Health System Cancer Institute-Easley Completed
Easley, South Carolina, United States, 29640
Greenville Health System Cancer Institute-Faris Completed
Greenville, South Carolina, United States, 29605
Greenville Health System Cancer Institute-Butternut Completed
Greenville, South Carolina, United States, 29605
Greenville Health System Cancer Institute-Eastside Completed
Greenville, South Carolina, United States, 29615
Greenville Memorial Hospital Completed
Greenville, South Carolina, United States, 29605
Saint Francis Cancer Center Completed
Greenville, South Carolina, United States, 29607
Saint Francis Hospital Completed
Greenville, South Carolina, United States, 29601
Greenville Health System Cancer Institute-Andrews Completed
Greenville, South Carolina, United States, 29605
Self Regional Healthcare Completed
Greenwood, South Carolina, United States, 29646
Greenville Health System Cancer Institute-Greer Completed
Greer, South Carolina, United States, 29650
Cancer Centers of the Carolinas-Greer Medical Oncology Withdrawn
Greer, South Carolina, United States, 29650
Gibbs Cancer Center-Pelham Completed
Greer, South Carolina, United States, 29651
Carolina Blood and Cancer Care Associates PA-Lancaster Completed
Lancaster, South Carolina, United States, 29720
Carolina Blood and Cancer Care Associates PA Completed
Rock Hill, South Carolina, United States, 29732
Greenville Health System Cancer Institute-Seneca Completed
Seneca, South Carolina, United States, 29672
Greenville Health System Cancer Institute-Spartanburg Completed
Spartanburg, South Carolina, United States, 29307
Spartanburg Medical Center Completed
Spartanburg, South Carolina, United States, 29303
Upstate Carolina CCOP Terminated
Spartanburg, South Carolina, United States, 29303
United States, South Dakota
Rapid City Regional Hospital Completed
Rapid City, South Dakota, United States, 57701
Avera Cancer Institute Completed
Sioux Falls, South Dakota, United States, 57105
Avera McKennan Hospital and University Health Center Completed
Sioux Falls, South Dakota, United States, 57105
United States, Tennessee
Wellmont Bristol Regional Medical Center Completed
Bristol, Tennessee, United States, 37620
Wellmont Medical Associates Oncology and Hematology-Bristol Completed
Bristol, Tennessee, United States, 37620
Memorial Hospital Completed
Chattanooga, Tennessee, United States, 37404
Pulmonary Medicine Center of Chattanooga-Hixson Completed
Hixson, Tennessee, United States, 37343
Jackson-Madison County General Hospital Withdrawn
Jackson, Tennessee, United States, 38301
Wellmont Holston Valley Hospital and Medical Center Completed
Kingsport, Tennessee, United States, 37660
Wellmont Medical Associates Oncology and Hematology-Kingsport Completed
Kingsport, Tennessee, United States, 37660
University of Tennessee - Knoxville Completed
Knoxville, Tennessee, United States, 37920
Meharry Medical College Completed
Nashville, Tennessee, United States, 37208
Nashville Oncology Associates PC Completed
Nashville, Tennessee, United States, 37203
Memorial GYN Plus Completed
Ooltewah, Tennessee, United States, 37363
United States, Texas
The Don and Sybil Harrington Cancer Center Completed
Amarillo, Texas, United States, 79106
Texas Technology University Completed
El Paso, Texas, United States, 79905
Baylor College of Medicine Completed
Houston, Texas, United States, 77030
Ben Taub General Hospital Completed
Houston, Texas, United States, 77030
Methodist Hospital Completed
Houston, Texas, United States, 77030
Saint Luke's Episcopal Hospital Completed
Houston, Texas, United States, 77030
Veterans Administration Medical Center Completed
Houston, Texas, United States, 77030
United States, Vermont
Central Vermont Medical Center/National Life Cancer Treatment Completed
Berlin, Vermont, United States, 05602
University of Vermont College of Medicine Completed
Burlington, Vermont, United States, 05405
White River Junction Veteran Administration Medical Center Recruiting
White River Junction, Vermont, United States, 05009
Contact: Nancy B. Kuemmerle       calgbco@calgb.org   
Principal Investigator: Nancy B. Kuemmerle         
United States, Virginia
Danville Hematology Oncology Completed
Danville, Virginia, United States, 24541
Danville Regional Medical Center Completed
Danville, Virginia, United States, 24541
Fredericksburg Oncology Inc Withdrawn
Fredericksburg, Virginia, United States, 22401
Memorial Hospital Of Martinsville Completed
Martinsville, Virginia, United States, 24115
Southwest VA Regional Cancer Center Completed
Norton, Virginia, United States, 24273
United States, Washington
Cancer Care Center at Island Hospital Completed
Anacortes, Washington, United States, 98221
Auburn Regional Medical Center Completed
Auburn, Washington, United States, 98001
Virginia Mason Bainbridge Island Medical Center Completed
Bainbridge Island, Washington, United States, 98110
Overlake Hospital Medical Center Completed
Bellevue, Washington, United States, 98004
PeaceHealth Saint Joseph Medical Center Completed
Bellingham, Washington, United States, 98225
Harrison HealthPartners Hematology and Oncology-Bremerton Completed
Bremerton, Washington, United States, 98310
Harrison Medical Center Completed
Bremerton, Washington, United States, 98310
Highline Medical Center-Main Campus Completed
Burien, Washington, United States, 98166
Providence Regional Cancer System-Centralia Completed
Centralia, Washington, United States, 98531
Swedish Medical Center-Edmonds Completed
Edmonds, Washington, United States, 98026
Saint Elizabeth Hospital Completed
Enumclaw, Washington, United States, 98022
Providence Regional Cancer Partnership Completed
Everett, Washington, United States, 98201
Saint Francis Hospital Completed
Federal Way, Washington, United States, 98003
Virginia Mason Federal Way Medical Center Completed
Federal Way, Washington, United States, 98002
Tacoma/Valley Radiation Oncology Centers-Gig Harbor Completed
Gig Harbor, Washington, United States, 98332
MultiCare Gig Harbor Medical Park Completed
Gig Harbor, Washington, United States, 98335
Swedish Cancer Institute-Issaquah Completed
Issaquah, Washington, United States, 98029
Kadlec Clinic Hematology and Oncology Completed
Kennewick, Washington, United States, 99336
Northwest Cancer Clinic Completed
Kennewick, Washington, United States, 99336
Providence Regional Cancer System-Lacey Completed
Lacey, Washington, United States, 98503
Saint Clare Hospital Completed
Lakewood, Washington, United States, 98499
Virginia Mason Lynnwood Medical Center Completed
Lynnwood, Washington, United States, 98036
Skagit Valley Hospital Completed
Mount Vernon, Washington, United States, 98274
Capital Medical Center Completed
Olympia, Washington, United States, 98507
Providence - Saint Peter Hospital Completed
Olympia, Washington, United States, 98506-5166
Harrison HealthPartners Hematology and Oncology-Poulsbo Completed
Poulsbo, Washington, United States, 98370
Peninsula Cancer Center Completed
Poulsbo, Washington, United States, 98370
MultiCare Good Samaritan Hospital Completed
Puyallup, Washington, United States, 98372
Tacoma/Valley Radiation Oncology Centers-Puyallup Completed
Puyallup, Washington, United States, 98372
Harborview Medical Center Completed
Seattle, Washington, United States, 98104
Group Health Cooperative-Seattle Completed
Seattle, Washington, United States, 98112
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Completed
Seattle, Washington, United States, 98109
Minor and James Medical PLLC Completed
Seattle, Washington, United States, 98104
Swedish Medical Center-First Hill Completed
Seattle, Washington, United States, 98122-4307
University of Washington Medical Center Completed
Seattle, Washington, United States, 98195
Virginia Mason Medical Center Completed
Seattle, Washington, United States, 98101
United General Hospital Completed
Sedro-Woolley, Washington, United States, 98284
Cancer Care Northwest - Spokane South Completed
Spokane, Washington, United States, 99202
Evergreen Hematology and Oncology PS Completed
Spokane, Washington, United States, 99218
Rockwood Clinic Completed
Spokane, Washington, United States, 99220
MultiCare Allenmore Hospital Completed
Tacoma, Washington, United States, 98405
Tacoma/Valley Radiation Oncology Centers-Saint Joe's Completed
Tacoma, Washington, United States, 98405
Multicare Health System Completed
Tacoma, Washington, United States, 98415
Northwest CCOP Terminated
Tacoma, Washington, United States, 98405
Northwest Medical Specialties PLLC Completed
Tacoma, Washington, United States, 98405
Saint Joseph Medical Center Completed
Tacoma, Washington, United States, 98405
Franciscan Research Center-Northwest Medical Plaza Completed
Tacoma, Washington, United States, 98405
Tacoma/Valley Radiation Oncology Centers-Jackson Hall Completed
Tacoma, Washington, United States, 97405
Wenatchee Valley Hospital and Clinics Completed
Wenatchee, Washington, United States, 98801
United States, Wisconsin
Langlade Hospital and Cancer Center Completed
Antigo, Wisconsin, United States, 54409
Saint Vincent Hospital Completed
Green Bay, Wisconsin, United States, 54301
Green Bay Oncology Limited at Saint Mary's Hospital Completed
Green Bay, Wisconsin, United States, 54303
Saint Mary's Hospital Completed
Green Bay, Wisconsin, United States, 54303
Green Bay Oncology at Saint Vincent Hospital Completed
Green Bay, Wisconsin, United States, 54301-3526
Gundersen Lutheran Medical Center Completed
La Crosse, Wisconsin, United States, 54601
Holy Family Memorial Hospital Completed
Manitowoc, Wisconsin, United States, 54221
Bay Area Medical Center Completed
Marinette, Wisconsin, United States, 54143
D N Greenwald Center Completed
Mukwonago, Wisconsin, United States, 53149
Cancer Center of Western Wisconsin Completed
New Richmond, Wisconsin, United States, 54017
Oconomowoc Memorial Hospital-ProHealth Care Inc Completed
Oconomowoc, Wisconsin, United States, 53066-3896
Green Bay Oncology - Oconto Falls Completed
Oconto Falls, Wisconsin, United States, 54154
Saint Nicholas Hospital Completed
Sheboygan, Wisconsin, United States, 53081
Green Bay Oncology - Sturgeon Bay Completed
Sturgeon Bay, Wisconsin, United States, 54235
Waukesha Memorial Hospital Completed
Waukesha, Wisconsin, United States, 53188
Aspirus Regional Cancer Center Completed
Wausau, Wisconsin, United States, 54401
Canada, Alberta
Tom Baker Cancer Centre Completed
Calgary, Alberta, Canada, T2N 4N2
Canada, British Columbia
BCCA-Vancouver Cancer Centre Completed
Vancouver, British Columbia, Canada, V5Z 4E6
Canada, Manitoba
CancerCare Manitoba Completed
Winnipeg, Manitoba, Canada, R3E 0V9
Canada, New Brunswick
The Moncton Hospital Completed
Moncton, New Brunswick, Canada, E1C 6Z8
Canada, Ontario
Grand River Regional Cancer Centre at Grand River Hospital Completed
Kitchener, Ontario, Canada, N2G 1G3
London Regional Cancer Program Completed
London, Ontario, Canada, N6A 4L6
Ottawa Health Research Institute-General Division Completed
Ottawa, Ontario, Canada, K1H 1C4
University Health Network-Princess Margaret Hospital Completed
Toronto, Ontario, Canada, M5G 2M9
Canada, Quebec
CHUM - Pavillon Saint-Luc Completed
Montreal, Quebec, Canada, H2X 3J4
McGill University Department of Oncology Completed
Montreal, Quebec, Canada, H2W 1S6
Canada, Saskatchewan
Saskatoon Cancer Centre Completed
Saskatoon, Saskatchewan, Canada, S7N 4H4
Puerto Rico
Fundacion De Investigacion de Diego Completed
San Juan, Puerto Rico, 00927
Sponsors and Collaborators
Investigators
Principal Investigator: Ghassan Abou-Alfa Alliance for Clinical Trials in Oncology
  More Information

No publications provided

Responsible Party: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT01015833     History of Changes
Other Study ID Numbers: NCI-2011-01989, NCI-2011-01989, CDR0000659348, CALGB 80802, CALGB-80802, U10CA180821, U10CA031946
Study First Received: November 17, 2009
Last Updated: May 26, 2015
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Carcinoma
Carcinoma, Hepatocellular
Adenocarcinoma
Digestive System Diseases
Digestive System Neoplasms
Liver Diseases
Liver Neoplasms
Neoplasms
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Glandular and Epithelial
Doxorubicin
Liposomal doxorubicin
Niacinamide
Sorafenib
Antibiotics, Antineoplastic
Antineoplastic Agents
Enzyme Inhibitors
Growth Substances
Micronutrients
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Physiological Effects of Drugs
Protein Kinase Inhibitors
Therapeutic Uses
Topoisomerase II Inhibitors
Topoisomerase Inhibitors
Vitamin B Complex
Vitamins

ClinicalTrials.gov processed this record on May 26, 2015