Thyroid Function in Late Preterm Infants
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|ClinicalTrials.gov Identifier: NCT00971555|
Recruitment Status : Completed
First Posted : September 3, 2009
Last Update Posted : March 23, 2011
Transient hypothyroxinemia (TH) is a condition characterized by low levels of serum thyroxine (T4) and normal levels of thyroid stimulating hormone (TSH). TH in premature infants has been found to be related to severity of illness. T4 levels in very low birth weight infants born prematurely has been found to be inversely correlated to severity of illness. In very low birth weight infants, TH has been associated with poor outcomes. Little is known about thyroid function in late preterm infants.
- Ill late preterm infants will have lower total T4 levels than healthy late preterm infants.
- Total T4 and possibly TSH levels will be inversely correlated with short-term outcomes.
- Late Preterm infants born by cesarean section will have lower T4 levels compared to those born by vaginal birth.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||150 participants|
|Official Title:||Thyroid Function in Late Preterm Infants in Relation to Severity of Illness|
|Study Start Date :||September 2009|
|Actual Primary Completion Date :||January 2011|
|Actual Study Completion Date :||January 2011|
Late preterm infants admitted to the NICU
- Correlation of total T4 and TSH with gestational age, birth weight, and mode of delivery. [ Time Frame: First week of life ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00971555
|United States, Delaware|
|Newark, Delaware, United States, 19718|
|Principal Investigator:||Renee M Behme, MD||Christiana Hospital|
|Principal Investigator:||David A Paul, MD||Christiana Hospital|