We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Syndrome (RLS)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00887289
First Posted: April 23, 2009
Last Update Posted: June 27, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Boehringer Ingelheim
  Purpose

The main goal of this open-label, prospective, non-controlled, non-interventional post marketing surveillance study is to evaluate how pramipexole treatment works when applied in actual practice. In actual practice patients who would have been excluded in the clinical registration studies of pramipexole in moderate to severe primary Restless Legs Syndrome (i.e. those with certain disease histories, co-morbidities and/or demographic characteristics) will also be treated with pramipexole. Thus, during this post marketing surveillance study additional information on the efficacy and safety of pramipexole in those patients will be obtained. The objectives of this post marketing surveillance study are:

  • To investigate the influence of Sifrol® (pramipexole) treatment on unpleasant sensory symptoms of Restless Legs Syndrome as measured with the short form of the McGill Pain Questionnaire.
  • To assess if improvement of sensory symptoms correlates with overall Restless Legs Syndrome severity (International Restless Legs Syndrome Scale for Severity) and with secondary symptoms like sleeping problems and daytime tiredness (items 1 & 6 from Restless Legs Syndrome-6).
  • To evaluate if the treatment effect of Sifrol on overall Restless Legs Syndrome severity (International Restless Legs Syndrome Scale for Severity) differs between patients with high pain scores and patients with lower pain scores.
  • To compare General Practitioner and neurologist sites patient populations in terms of demographics, Restless Legs Syndrome severity at Visit 1 and treatment outcomes at Visit 3.
  • To evaluate the development of behavioural changes under pramipexole treatment.

Condition
Restless Legs Syndrome

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Non-interventional Observational Study on the Influence of Pramipexole (PPX) on Sensory Symptoms of Restless Legs Syndrome (RLS)

Resource links provided by NLM:


Further study details as provided by Boehringer Ingelheim:

Primary Outcome Measures:
  • Summary of Change From Baseline in Total Sum of McGill Pain Questionnaire to Visit 3 [ Time Frame: Baseline to Visit 3 ]
    Change in Total Sum Score of McGill Pain Questionnaire at Visit 3 to baseline. The sum scores can have values in the range from 0 (no pain) to 20 (worst pain). A negative change is an improvement of pain, a positive change a worsening of pain.

  • Summary of Change From Baseline in Total Sum of McGill Pain Questionnaire to Visit 3 for Patients Treated by General Practitioner [ Time Frame: Baseline to Visit 3 ]
    Change in Total Sum Score of McGill Pain Questionnaire at Visit 3 to baseline. The sum scores can have values in the range from 0 (no pain) to 20 (worst pain). A negative change is an improvement of pain, a positive change a worsening of pain.

  • Summary of Change From Baseline in Total Sum of McGill Pain Questionnaire to Visit 3 for Patients Treated by Neurologist [ Time Frame: Baseline to Visit 3 ]
    Change in Total Sum Score of McGill Pain Questionnaire at Visit 3 to baseline. The sum scores can have values in the range from 0 (no pain) to 20 (worst pain). A negative change is an improvement of pain, a positive change a worsening of pain.


Secondary Outcome Measures:
  • Summary of Change From Baseline in Restless Legs Syndrome Severity Scale With 6 Questions to Visit 3 [ Time Frame: Baseline to Visit 3 ]
    Change in RLS-6 at Visit 3 to baseline. The sum scores can have values in the range from 0 (best) to 20 (worst) A negative change is an improvement of RLS-6, a positive change a worsening of RLS-6.

  • Summary of Change From Baseline in International Restless Legs Syndrome Scale for Severity to Visit 3 [ Time Frame: Baseline to Visit 3 ]
    Change in IRLS at Visit 3 to baseline. The sum scores can have values in the range from 0 (best) to 40 (worst) A negative change is an improvement of IRLS, a positive change a worsening of IRLS.

  • Behavioural Changes During Treatment [ Time Frame: Baseline to Visit 3 ]
    Number of patients with occurence of behavioural changes in terms of impulse control disorders


Enrollment: 1504
Study Start Date: April 2009
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Detailed Description:
Study Design:
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
RLS patients
Criteria

Inclusion criteria:

  1. Diagnosis of primary moderate to severe Restless Legs Syndrome.
  2. Patients who are planned to be treated with Sifrol® (pramipexole) and where the decision of treatment is made independent of the patients' inclusion into this post marketing surveillance study.
  3. Male or female patients aged at least 18 years.
  4. Written informed consent by the patient for study participation.

Exclusion criteria:

  1. Any contraindications according to the Summary of Product Characteristics: hypersensitivity to pramipexole or to any of the excipients.
  2. Previous or ongoing treatment with Sifrol® (pramipexole).
  3. Previous or ongoing treatment with dopamine receptor agonists.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00887289


  Hide Study Locations
Locations
Germany
Boehringer Ingelheim Investigational Site
Aalen, Germany
Boehringer Ingelheim Investigational Site 1
Achim, Germany
Boehringer Ingelheim Investigational Site 2
Achim, Germany
Boehringer Ingelheim Investigational Site 1
Ahrensburg, Germany
Boehringer Ingelheim Investigational Site 2
Ahrensburg, Germany
Boehringer Ingelheim Investigational Site
Albstadt, Germany
Boehringer Ingelheim Investigational Site
Alfeld, Germany
Boehringer Ingelheim Investigational Site
Allendorf, Germany
Boehringer Ingelheim Investigational Site 1
Alzenau, Germany
Boehringer Ingelheim Investigational Site 2
Alzenau, Germany
Boehringer Ingelheim Investigational Site
Anklam, Germany
Boehringer Ingelheim Investigational Site
Annaberg-Buchholz, Germany
Boehringer Ingelheim Investigational Site
Ansbach, Germany
Boehringer Ingelheim Investigational Site
Apolda, Germany
Boehringer Ingelheim Investigational Site
Arenshausen, Germany
Boehringer Ingelheim Investigational Site 1
Arnsberg, Germany
Boehringer Ingelheim Investigational Site 2
Arnsberg, Germany
Boehringer Ingelheim Investigational Site
Asperg, Germany
Boehringer Ingelheim Investigational Site 1
Attendorn, Germany
Boehringer Ingelheim Investigational Site 2
Attendorn, Germany
Boehringer Ingelheim Investigational Site
Aue, Germany
Boehringer Ingelheim Investigational Site 1
Augsburg, Germany
Boehringer Ingelheim Investigational Site 2
Augsburg, Germany
Boehringer Ingelheim Investigational Site 3
Augsburg, Germany
Boehringer Ingelheim Investigational Site
Aurich, Germany
Boehringer Ingelheim Investigational Site
Backnang, Germany
Boehringer Ingelheim Investigational Site
Bad Arolsen, Germany
Boehringer Ingelheim Investigational Site
Bad Bevensen, Germany
Boehringer Ingelheim Investigational Site
Bad Ems, Germany
Boehringer Ingelheim Investigational Site 1
Bad Hersfeld, Germany
Boehringer Ingelheim Investigational Site 2
Bad Hersfeld, Germany
Boehringer Ingelheim Investigational Site 1
Bad Honnef, Germany
Boehringer Ingelheim Investigational Site 2
Bad Honnef, Germany
Boehringer Ingelheim Investigational Site
Bad Krozingen, Germany
Boehringer Ingelheim Investigational Site
Bad Laer, Germany
Boehringer Ingelheim Investigational Site
Bad Lausick, Germany
Boehringer Ingelheim Investigational Site
Bad Marienberg, Germany
Boehringer Ingelheim Investigational Site 1
Bad Neuenahr-Ahrweiler, Germany
Boehringer Ingelheim Investigational Site 2
Bad Neuenahr-Ahrweiler, Germany
Boehringer Ingelheim Investigational Site
Bad Neustadt, Germany
Boehringer Ingelheim Investigational Site
Bad Reichenhall, Germany
Boehringer Ingelheim Investigational Site
Bad Sachsa, Germany
Boehringer Ingelheim Investigational Site
Bad Salzuflen, Germany
Boehringer Ingelheim Investigational Site 1
Bad Salzungen, Germany
Boehringer Ingelheim Investigational Site 2
Bad Salzungen, Germany
Boehringer Ingelheim Investigational Site 3
Bad Salzungen, Germany
Boehringer Ingelheim Investigational Site
Bad Schwartau, Germany
Boehringer Ingelheim Investigational Site 1
Bad Segeberg, Germany
Boehringer Ingelheim Investigational Site 2
Bad Segeberg, Germany
Boehringer Ingelheim Investigational Site
Bad Sooden-Allendorf, Germany
Boehringer Ingelheim Investigational Site
Bad Tennstedt, Germany
Boehringer Ingelheim Investigational Site
Bad Wörishofen, Germany
Boehringer Ingelheim Investigational Site
Baden-Baden, Germany
Boehringer Ingelheim Investigational Site
Baesweiler, Germany
Boehringer Ingelheim Investigational Site 1
Bamberg, Germany
Boehringer Ingelheim Investigational Site 2
Bamberg, Germany
Boehringer Ingelheim Investigational Site 3
Bamberg, Germany
Boehringer Ingelheim Investigational Site
Baunatal, Germany
Boehringer Ingelheim Investigational Site
Bautzen, Germany
Boehringer Ingelheim Investigational Site 1
Bayreuth, Germany
Boehringer Ingelheim Investigational Site 2
Bayreuth, Germany
Boehringer Ingelheim Investigational Site
Bergheim, Germany
Boehringer Ingelheim Investigational Site 1
Bergkamen, Germany
Boehringer Ingelheim Investigational Site 2
Bergkamen, Germany
Boehringer Ingelheim Investigational Site 10
Berlin, Germany
Boehringer Ingelheim Investigational Site 11
Berlin, Germany
Boehringer Ingelheim Investigational Site 12
Berlin, Germany
Boehringer Ingelheim Investigational Site 13
Berlin, Germany
Boehringer Ingelheim Investigational Site 14
Berlin, Germany
Boehringer Ingelheim Investigational Site 15
Berlin, Germany
Boehringer Ingelheim Investigational Site 16
Berlin, Germany
Boehringer Ingelheim Investigational Site 17
Berlin, Germany
Boehringer Ingelheim Investigational Site 18
Berlin, Germany
Boehringer Ingelheim Investigational Site 19
Berlin, Germany
Boehringer Ingelheim Investigational Site 1
Berlin, Germany
Boehringer Ingelheim Investigational Site 20
Berlin, Germany
Boehringer Ingelheim Investigational Site 21
Berlin, Germany
Boehringer Ingelheim Investigational Site 22
Berlin, Germany
Boehringer Ingelheim Investigational Site 23
Berlin, Germany
Boehringer Ingelheim Investigational Site 24
Berlin, Germany
Boehringer Ingelheim Investigational Site 25
Berlin, Germany
Boehringer Ingelheim Investigational Site 26
Berlin, Germany
Boehringer Ingelheim Investigational Site 27
Berlin, Germany
Boehringer Ingelheim Investigational Site 28
Berlin, Germany
Boehringer Ingelheim Investigational Site 29
Berlin, Germany
Boehringer Ingelheim Investigational Site 2
Berlin, Germany
Boehringer Ingelheim Investigational Site 30
Berlin, Germany
Boehringer Ingelheim Investigational Site 31
Berlin, Germany
Boehringer Ingelheim Investigational Site 32
Berlin, Germany
Boehringer Ingelheim Investigational Site 33
Berlin, Germany
Boehringer Ingelheim Investigational Site 3
Berlin, Germany
Boehringer Ingelheim Investigational Site 4
Berlin, Germany
Boehringer Ingelheim Investigational Site 5
Berlin, Germany
Boehringer Ingelheim Investigational Site 6
Berlin, Germany
Boehringer Ingelheim Investigational Site 7
Berlin, Germany
Boehringer Ingelheim Investigational Site 8
Berlin, Germany
Boehringer Ingelheim Investigational Site 9
Berlin, Germany
Boehringer Ingelheim Investigational Site
Biberach, Germany
Boehringer Ingelheim Investigational Site
Bielefeld, Germany
Boehringer Ingelheim Investigational Site
Bingen, Germany
Boehringer Ingelheim Investigational Site
Bissendorf, Germany
Boehringer Ingelheim Investigational Site
Bitterfeld, Germany
Boehringer Ingelheim Investigational Site
Blankenhagen, Germany
Boehringer Ingelheim Investigational Site
Blaustein, Germany
Boehringer Ingelheim Investigational Site
Blieskastel, Germany
Boehringer Ingelheim Investigational Site 1
Bochum, Germany
Boehringer Ingelheim Investigational Site 2
Bochum, Germany
Boehringer Ingelheim Investigational Site 3
Bochum, Germany
Boehringer Ingelheim Investigational Site 4
Bochum, Germany
Boehringer Ingelheim Investigational Site 5
Bochum, Germany
Boehringer Ingelheim Investigational Site 6
Bochum, Germany
Boehringer Ingelheim Investigational Site 7
Bochum, Germany
Boehringer Ingelheim Investigational Site 1
Bockhorn, Germany
Boehringer Ingelheim Investigational Site 2
Bockhorn, Germany
Boehringer Ingelheim Investigational Site 1
Bodelshausen, Germany
Boehringer Ingelheim Investigational Site 2
Bodelshausen, Germany
Boehringer Ingelheim Investigational Site 1
Bonn, Germany
Boehringer Ingelheim Investigational Site 2
Bonn, Germany
Boehringer Ingelheim Investigational Site
Bordesholm, Germany
Boehringer Ingelheim Investigational Site
Bottrop, Germany
Boehringer Ingelheim Investigational Site
Braunschweig, Germany
Boehringer Ingelheim Investigational Site 1
Bremen, Germany
Boehringer Ingelheim Investigational Site 2
Bremen, Germany
Boehringer Ingelheim Investigational Site 3
Bremen, Germany
Boehringer Ingelheim Investigational Site 1
Bremerhaven, Germany
Boehringer Ingelheim Investigational Site 2
Bremerhaven, Germany
Boehringer Ingelheim Investigational Site 3
Bremerhaven, Germany
Boehringer Ingelheim Investigational Site
Breuberg, Germany
Boehringer Ingelheim Investigational Site
Bruchsal, Germany
Boehringer Ingelheim Investigational Site
Brühl, Germany
Boehringer Ingelheim Investigational Site
Buchbach, Germany
Boehringer Ingelheim Investigational Site
Buchen, Germany
Boehringer Ingelheim Investigational Site
Burgdorf, Germany
Boehringer Ingelheim Investigational Site
Burglengenfeld, Germany
Boehringer Ingelheim Investigational Site
Burscheid, Germany
Boehringer Ingelheim Investigational Site 1
Butzbach, Germany
Boehringer Ingelheim Investigational Site 2
Butzbach, Germany
Boehringer Ingelheim Investigational Site
Buxtehude, Germany
Boehringer Ingelheim Investigational Site
Büchen, Germany
Boehringer Ingelheim Investigational Site
Bückeburg, Germany
Boehringer Ingelheim Investigational Site
Calw, Germany
Boehringer Ingelheim Investigational Site 1
Celle, Germany
Boehringer Ingelheim Investigational Site 2
Celle, Germany
Boehringer Ingelheim Investigational Site 1
Chemnitz, Germany
Boehringer Ingelheim Investigational Site 2
Chemnitz, Germany
Boehringer Ingelheim Investigational Site 3
Chemnitz, Germany
Boehringer Ingelheim Investigational Site 4
Chemnitz, Germany
Boehringer Ingelheim Investigational Site 5
Chemnitz, Germany
Boehringer Ingelheim Investigational Site
Coburg, Germany
Boehringer Ingelheim Investigational Site
Coesfeld, Germany
Boehringer Ingelheim Investigational Site
Cottbus, Germany
Boehringer Ingelheim Investigational Site 1
Crimmitschau, Germany
Boehringer Ingelheim Investigational Site 2
Crimmitschau, Germany
Boehringer Ingelheim Investigational Site
Dachau, Germany
Boehringer Ingelheim Investigational Site
Delbrück, Germany
Boehringer Ingelheim Investigational Site
Delmenhorst, Germany
Boehringer Ingelheim Investigational Site
Dernau, Germany
Boehringer Ingelheim Investigational Site 1
Dessau, Germany
Boehringer Ingelheim Investigational Site 2
Dessau, Germany
Boehringer Ingelheim Investigational Site 3
Dessau, Germany
Boehringer Ingelheim Investigational Site 4
Dessau, Germany
Boehringer Ingelheim Investigational Site 1
Dietzenbach, Germany
Boehringer Ingelheim Investigational Site 2
Dietzenbach, Germany
Boehringer Ingelheim Investigational Site 3
Dietzenbach, Germany
Boehringer Ingelheim Investigational Site
Dillingen, Germany
Boehringer Ingelheim Investigational Site
Dinkelsbühl, Germany
Boehringer Ingelheim Investigational Site 1
Dippoldiswalde, Germany
Boehringer Ingelheim Investigational Site 2
Dippoldiswalde, Germany
Boehringer Ingelheim Investigational Site 1
Dortmund, Germany
Boehringer Ingelheim Investigational Site 2
Dortmund, Germany
Boehringer Ingelheim Investigational Site 3
Dortmund, Germany
Boehringer Ingelheim Investigational Site 4
Dortmund, Germany
Boehringer Ingelheim Investigational Site 1
Dresden, Germany
Boehringer Ingelheim Investigational Site 2
Dresden, Germany
Boehringer Ingelheim Investigational Site 3
Dresden, Germany
Boehringer Ingelheim Investigational Site
Driedorf, Germany
Boehringer Ingelheim Investigational Site
Duderstadt, Germany
Boehringer Ingelheim Investigational Site 1
Duisburg, Germany
Boehringer Ingelheim Investigational Site 2
Duisburg, Germany
Boehringer Ingelheim Investigational Site 3
Duisburg, Germany
Boehringer Ingelheim Investigational Site
Durmersheim, Germany
Boehringer Ingelheim Investigational Site
Döbeln, Germany
Boehringer Ingelheim Investigational Site 1
Dörentrup, Germany
Boehringer Ingelheim Investigational Site 2
Dörentrup, Germany
Boehringer Ingelheim Investigational Site 1
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 2
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 3
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 4
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 5
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 6
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 7
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 8
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site 9
Düsseldorf, Germany
Boehringer Ingelheim Investigational Site
Ebermannstadt, Germany
Boehringer Ingelheim Investigational Site 1
Edingen-Neckarhausen, Germany
Boehringer Ingelheim Investigational Site 2
Edingen-Neckarhausen, Germany
Boehringer Ingelheim Investigational Site
Edling, Germany
Boehringer Ingelheim Investigational Site
Eilenburg, Germany
Boehringer Ingelheim Investigational Site 1
Eisenach, Germany
Boehringer Ingelheim Investigational Site 2
Eisenach, Germany
Boehringer Ingelheim Investigational Site
Eisenberg, Germany
Boehringer Ingelheim Investigational Site
Eisenhüttenstadt, Germany
Boehringer Ingelheim Investigational Site
Ellwangen, Germany
Boehringer Ingelheim Investigational Site
Emmendingen, Germany
Boehringer Ingelheim Investigational Site
Emsdetten, Germany
Boehringer Ingelheim Investigational Site
Emskirchen, Germany
Boehringer Ingelheim Investigational Site
Enkirch, Germany
Boehringer Ingelheim Investigational Site
Ennigerloh, Germany
Boehringer Ingelheim Investigational Site
Eppelheim, Germany
Boehringer Ingelheim Investigational Site 1
Erbach, Germany
Boehringer Ingelheim Investigational Site 2
Erbach, Germany
Boehringer Ingelheim Investigational Site 3
Erbach, Germany
Boehringer Ingelheim Investigational Site 1
Erfurt, Germany
Boehringer Ingelheim Investigational Site 2
Erfurt, Germany
Boehringer Ingelheim Investigational Site 3
Erfurt, Germany
Boehringer Ingelheim Investigational Site
Erkrath, Germany
Boehringer Ingelheim Investigational Site 1
Erlangen, Germany
Boehringer Ingelheim Investigational Site
Eschborn, Germany
Boehringer Ingelheim Investigational Site
Eschlkam, Germany
Boehringer Ingelheim Investigational Site 10
Essen, Germany
Boehringer Ingelheim Investigational Site 11
Essen, Germany
Boehringer Ingelheim Investigational Site 12
Essen, Germany
Boehringer Ingelheim Investigational Site 13
Essen, Germany
Boehringer Ingelheim Investigational Site 14
Essen, Germany
Boehringer Ingelheim Investigational Site 1
Essen, Germany
Boehringer Ingelheim Investigational Site 2
Essen, Germany
Boehringer Ingelheim Investigational Site 3
Essen, Germany
Boehringer Ingelheim Investigational Site 4
Essen, Germany
Boehringer Ingelheim Investigational Site 5
Essen, Germany
Boehringer Ingelheim Investigational Site 6
Essen, Germany
Boehringer Ingelheim Investigational Site 7
Essen, Germany
Boehringer Ingelheim Investigational Site 8
Essen, Germany
Boehringer Ingelheim Investigational Site 9
Essen, Germany
Boehringer Ingelheim Investigational Site
Ettlingen, Germany
Boehringer Ingelheim Investigational Site
Extertal, Germany
Boehringer Ingelheim Investigational Site
Falkenhagen, Germany
Boehringer Ingelheim Investigational Site
Fehrbellin, Germany
Boehringer Ingelheim Investigational Site
Flintbek, Germany
Boehringer Ingelheim Investigational Site 1
Frankfurt, Germany
Boehringer Ingelheim Investigational Site 2
Frankfurt, Germany
Boehringer Ingelheim Investigational Site 3
Frankfurt, Germany
Boehringer Ingelheim Investigational Site
Freiberg, Germany
Boehringer Ingelheim Investigational Site 1
Freiburg, Germany
Boehringer Ingelheim Investigational Site 2
Freiburg, Germany
Boehringer Ingelheim Investigational Site 3
Freiburg, Germany
Boehringer Ingelheim Investigational Site 4
Freiburg, Germany
Boehringer Ingelheim Investigational Site 5
Freiburg, Germany
Boehringer Ingelheim Investigational Site
Freilassing, Germany
Boehringer Ingelheim Investigational Site
Freinsheim, Germany
Boehringer Ingelheim Investigational Site 1
Freital, Germany
Boehringer Ingelheim Investigational Site 2
Freital, Germany
Boehringer Ingelheim Investigational Site 3
Freital, Germany
Boehringer Ingelheim Investigational Site
Friedrichshafen, Germany
Boehringer Ingelheim Investigational Site 1
Friedrichsthal, Germany
Boehringer Ingelheim Investigational Site 2
Friedrichsthal, Germany
Boehringer Ingelheim Investigational Site
Fulda, Germany
Boehringer Ingelheim Investigational Site
Fürstenfeldbruck, Germany
Boehringer Ingelheim Investigational Site 1
Fürstenwalde, Germany
Boehringer Ingelheim Investigational Site 2
Fürstenwalde, Germany
Boehringer Ingelheim Investigational Site
Fürstenzell, Germany
Boehringer Ingelheim Investigational Site 1
Fürth, Germany
Boehringer Ingelheim Investigational Site 2
Fürth, Germany
Boehringer Ingelheim Investigational Site
Gauting, Germany
Boehringer Ingelheim Investigational Site
Geisenhausen, Germany
Boehringer Ingelheim Investigational Site
Geithain, Germany
Boehringer Ingelheim Investigational Site 1
Gelnhausen, Germany
Boehringer Ingelheim Investigational Site 2
Gelnhausen, Germany
Boehringer Ingelheim Investigational Site 1
Gelsenkirchen, Germany
Boehringer Ingelheim Investigational Site 2
Gelsenkirchen, Germany
Boehringer Ingelheim Investigational Site 3
Gelsenkirchen, Germany
Boehringer Ingelheim Investigational Site 4
Gelsenkirchen, Germany
Boehringer Ingelheim Investigational Site
Gera, Germany
Boehringer Ingelheim Investigational Site
Gerbstedt, Germany
Boehringer Ingelheim Investigational Site
Germering, Germany
Boehringer Ingelheim Investigational Site
Gersthofen, Germany
Boehringer Ingelheim Investigational Site
Gingen, Germany
Boehringer Ingelheim Investigational Site
Gladbeck, Germany
Boehringer Ingelheim Investigational Site
Gladenbach, Germany
Boehringer Ingelheim Investigational Site
Glauchau, Germany
Boehringer Ingelheim Investigational Site
Gleichen, Germany
Boehringer Ingelheim Investigational Site
Glienicke, Germany
Boehringer Ingelheim Investigational Site
Glücksburg, Germany
Boehringer Ingelheim Investigational Site
Gosheim, Germany
Boehringer Ingelheim Investigational Site
Greifswald, Germany
Boehringer Ingelheim Investigational Site
Grevenbroich, Germany
Boehringer Ingelheim Investigational Site
Greven, Germany
Boehringer Ingelheim Investigational Site
Großefehn, Germany
Boehringer Ingelheim Investigational Site
Großmaischeid, Germany
Boehringer Ingelheim Investigational Site 1
Grömitz, Germany
Boehringer Ingelheim Investigational Site 2
Grömitz, Germany
Boehringer Ingelheim Investigational Site
Grüna, Germany
Boehringer Ingelheim Investigational Site
Grünheide, Germany
Boehringer Ingelheim Investigational Site
Grünstadt, Germany
Boehringer Ingelheim Investigational Site
Gudensberg, Germany
Boehringer Ingelheim Investigational Site
Gundelfingen, Germany
Boehringer Ingelheim Investigational Site
Göppingen, Germany
Boehringer Ingelheim Investigational Site 1
Göttingen, Germany
Boehringer Ingelheim Investigational Site 2
Göttingen, Germany
Boehringer Ingelheim Investigational Site 3
Göttingen, Germany
Boehringer Ingelheim Investigational Site 4
Göttingen, Germany
Boehringer Ingelheim Investigational Site 5
Göttingen, Germany
Boehringer Ingelheim Investigational Site
Gößweinstein, Germany
Boehringer Ingelheim Investigational Site
Güster, Germany
Boehringer Ingelheim Investigational Site
Haag, Germany
Boehringer Ingelheim Investigational Site
Halbe, Germany
Boehringer Ingelheim Investigational Site 1
Halle, Germany
Boehringer Ingelheim Investigational Site 2
Halle, Germany
Boehringer Ingelheim Investigational Site 3
Halle, Germany
Boehringer Ingelheim Investigational Site 4
Halle, Germany
Boehringer Ingelheim Investigational Site 5
Halle, Germany
Boehringer Ingelheim Investigational Site 10
Hamburg, Germany
Boehringer Ingelheim Investigational Site 11
Hamburg, Germany
Boehringer Ingelheim Investigational Site 12
Hamburg, Germany
Boehringer Ingelheim Investigational Site 13
Hamburg, Germany
Boehringer Ingelheim Investigational Site 14
Hamburg, Germany
Boehringer Ingelheim Investigational Site 15
Hamburg, Germany
Boehringer Ingelheim Investigational Site 16
Hamburg, Germany
Boehringer Ingelheim Investigational Site 17
Hamburg, Germany
Boehringer Ingelheim Investigational Site 18
Hamburg, Germany
Boehringer Ingelheim Investigational Site 19
Hamburg, Germany
Boehringer Ingelheim Investigational Site 1
Hamburg, Germany
Boehringer Ingelheim Investigational Site 20
Hamburg, Germany
Boehringer Ingelheim Investigational Site 21
Hamburg, Germany
Boehringer Ingelheim Investigational Site 22
Hamburg, Germany
Boehringer Ingelheim Investigational Site 23
Hamburg, Germany
Boehringer Ingelheim Investigational Site 24
Hamburg, Germany
Boehringer Ingelheim Investigational Site 25
Hamburg, Germany
Boehringer Ingelheim Investigational Site 2
Hamburg, Germany
Boehringer Ingelheim Investigational Site 3
Hamburg, Germany
Boehringer Ingelheim Investigational Site 4
Hamburg, Germany
Boehringer Ingelheim Investigational Site 5
Hamburg, Germany
Boehringer Ingelheim Investigational Site 6
Hamburg, Germany
Boehringer Ingelheim Investigational Site 7
Hamburg, Germany
Boehringer Ingelheim Investigational Site 8
Hamburg, Germany
Boehringer Ingelheim Investigational Site 9
Hamburg, Germany
Boehringer Ingelheim Investigational Site
Hameln, Germany
Boehringer Ingelheim Investigational Site
Hammelburg, Germany
Boehringer Ingelheim Investigational Site
Hamminkeln, Germany
Boehringer Ingelheim Investigational Site
Hann Münden, Germany
Boehringer Ingelheim Investigational Site 1
Hannover, Germany
Boehringer Ingelheim Investigational Site 2
Hannover, Germany
Boehringer Ingelheim Investigational Site 3
Hannover, Germany
Boehringer Ingelheim Investigational Site 4
Hannover, Germany
Boehringer Ingelheim Investigational Site 5
Hannover, Germany
Boehringer Ingelheim Investigational Site 6
Hannover, Germany
Boehringer Ingelheim Investigational Site 7
Hannover, Germany
Boehringer Ingelheim Investigational Site 1
Harsewinkel, Germany
Boehringer Ingelheim Investigational Site 2
Harsewinkel, Germany
Boehringer Ingelheim Investigational Site 3
Harsewinkel, Germany
Boehringer Ingelheim Investigational Site
Hartenstein, Germany
Boehringer Ingelheim Investigational Site
Hasbergen, Germany
Boehringer Ingelheim Investigational Site
Heilbad Heiligenstadt, Germany
Boehringer Ingelheim Investigational Site 1
Heilbronn, Germany
Boehringer Ingelheim Investigational Site 2
Heilbronn, Germany
Boehringer Ingelheim Investigational Site 3
Heilbronn, Germany
Boehringer Ingelheim Investigational Site
Heinsberg, Germany
Boehringer Ingelheim Investigational Site
Herborn, Germany
Boehringer Ingelheim Investigational Site
Herbrechtingen, Germany
Boehringer Ingelheim Investigational Site
Herdorf, Germany
Boehringer Ingelheim Investigational Site
Herne, Germany
Boehringer Ingelheim Investigational Site
Herrenberg, Germany
Boehringer Ingelheim Investigational Site
Herrnhut, Germany
Boehringer Ingelheim Investigational Site
Herrsching, Germany
Boehringer Ingelheim Investigational Site 1
Herzogenrath, Germany
Boehringer Ingelheim Investigational Site 2
Herzogenrath, Germany
Boehringer Ingelheim Investigational Site
Hessisch Lichtenau, Germany
Boehringer Ingelheim Investigational Site
Hettstedt, Germany
Boehringer Ingelheim Investigational Site
Hildburghausen, Germany
Boehringer Ingelheim Investigational Site 1
Hildesheim, Germany
Boehringer Ingelheim Investigational Site 2
Hildesheim, Germany
Boehringer Ingelheim Investigational Site 3
Hildesheim, Germany
Boehringer Ingelheim Investigational Site 4
Hildesheim, Germany
Boehringer Ingelheim Investigational Site 1
Hof, Germany
Boehringer Ingelheim Investigational Site 2
Hof, Germany
Boehringer Ingelheim Investigational Site
Hohenprießnitz, Germany
Boehringer Ingelheim Investigational Site
Holle, Germany
Boehringer Ingelheim Investigational Site
Horb, Germany
Boehringer Ingelheim Investigational Site
Höchberg, Germany
Boehringer Ingelheim Investigational Site
Hückeswagen, Germany
Boehringer Ingelheim Investigational Site 1
Hüllhorst, Germany
Boehringer Ingelheim Investigational Site 2
Hüllhorst, Germany
Boehringer Ingelheim Investigational Site 3
Hüllhorst, Germany
Boehringer Ingelheim Investigational Site 1
Hürth, Germany
Boehringer Ingelheim Investigational Site 2
Hürth, Germany
Boehringer Ingelheim Investigational Site
Ibbenbüren, Germany
Boehringer Ingelheim Investigational Site 1
Ilmenau, Germany
Boehringer Ingelheim Investigational Site 2
Ilmenau, Germany
Boehringer Ingelheim Investigational Site
Immenstadt, Germany
Boehringer Ingelheim Investigational Site
Ingelfingen, Germany
Boehringer Ingelheim Investigational Site
Ingelheim, Germany
Boehringer Ingelheim Investigational Site
Ingolstadt, Germany
Boehringer Ingelheim Investigational Site
Inning, Germany
Boehringer Ingelheim Investigational Site
Irsch, Germany
Boehringer Ingelheim Investigational Site 1
Iserlohn, Germany
Boehringer Ingelheim Investigational Site 2
Iserlohn, Germany
Boehringer Ingelheim Investigational Site 1
Itzehoe, Germany
Boehringer Ingelheim Investigational Site 2
Itzehoe, Germany
Boehringer Ingelheim Investigational Site 3
Itzehoe, Germany
Boehringer Ingelheim Investigational Site
Jettingen, Germany
Boehringer Ingelheim Investigational Site 1
Jülich, Germany
Boehringer Ingelheim Investigational Site 2
Jülich, Germany
Boehringer Ingelheim Investigational Site 3
Jülich, Germany
Boehringer Ingelheim Investigational Site 1
Jüterbog, Germany
Boehringer Ingelheim Investigational Site 2
Jüterbog, Germany
Boehringer Ingelheim Investigational Site 1
Kaiserslautern, Germany
Boehringer Ingelheim Investigational Site 2
Kaiserslautern, Germany
Boehringer Ingelheim Investigational Site
Kamen, Germany
Boehringer Ingelheim Investigational Site
Kandel, Germany
Boehringer Ingelheim Investigational Site
Karlsfeld, Germany
Boehringer Ingelheim Investigational Site 1
Karlsruhe, Germany
Boehringer Ingelheim Investigational Site 2
Karlsruhe, Germany
Boehringer Ingelheim Investigational Site 1
Kassel, Germany
Boehringer Ingelheim Investigational Site 2
Kassel, Germany
Boehringer Ingelheim Investigational Site 3
Kassel, Germany
Boehringer Ingelheim Investigational Site 4
Kassel, Germany
Boehringer Ingelheim Investigational Site 1
Kaufbeuren, Germany
Boehringer Ingelheim Investigational Site 2
Kaufbeuren, Germany
Boehringer Ingelheim Investigational Site 3
Kaufbeuren, Germany
Boehringer Ingelheim Investigational Site 1
Kempten, Germany
Boehringer Ingelheim Investigational Site 2
Kempten, Germany
Boehringer Ingelheim Investigational Site
Kenzingen, Germany
Boehringer Ingelheim Investigational Site
Kernen, Germany
Boehringer Ingelheim Investigational Site
Kiel, Germany
Boehringer Ingelheim Investigational Site
Kirchardt, Germany
Boehringer Ingelheim Investigational Site
Kirchen, Germany
Boehringer Ingelheim Investigational Site
Kirchheimbolanden, Germany
Boehringer Ingelheim Investigational Site
Kirchheim, Germany
Boehringer Ingelheim Investigational Site
Kißlegg, Germany
Boehringer Ingelheim Investigational Site
Kleve, Germany
Boehringer Ingelheim Investigational Site
Klingenberg, Germany
Boehringer Ingelheim Investigational Site
Konz, Germany
Boehringer Ingelheim Investigational Site
Krefeld, Germany
Boehringer Ingelheim Investigational Site
Kreuztal, Germany
Boehringer Ingelheim Investigational Site
Kronach, Germany
Boehringer Ingelheim Investigational Site 1
Köln, Germany
Boehringer Ingelheim Investigational Site 2
Köln, Germany
Boehringer Ingelheim Investigational Site 3
Köln, Germany
Boehringer Ingelheim Investigational Site 4
Köln, Germany
Boehringer Ingelheim Investigational Site 5
Köln, Germany
Boehringer Ingelheim Investigational Site 6
Köln, Germany
Boehringer Ingelheim Investigational Site 7
Köln, Germany
Boehringer Ingelheim Investigational Site 8
Köln, Germany
Boehringer Ingelheim Investigational Site 9
Köln, Germany
Boehringer Ingelheim Investigational Site
Königsbrunn, Germany
Boehringer Ingelheim Investigational Site
Kösching, Germany
Boehringer Ingelheim Investigational Site
Köthen, Germany
Boehringer Ingelheim Investigational Site
Laage, Germany
Boehringer Ingelheim Investigational Site
Lahnau, Germany
Boehringer Ingelheim Investigational Site
Laichingen, Germany
Boehringer Ingelheim Investigational Site
Lampertheim, Germany
Boehringer Ingelheim Investigational Site
Landshut, Germany
Boehringer Ingelheim Investigational Site
Langen, Germany
Boehringer Ingelheim Investigational Site
Langerwehe, Germany
Boehringer Ingelheim Investigational Site
Lauterbach, Germany
Boehringer Ingelheim Investigational Site 1
Leipzig, Germany
Boehringer Ingelheim Investigational Site 2
Leipzig, Germany
Boehringer Ingelheim Investigational Site 3
Leipzig, Germany
Boehringer Ingelheim Investigational Site 4
Leipzig, Germany
Boehringer Ingelheim Investigational Site 5
Leipzig, Germany
Boehringer Ingelheim Investigational Site 6
Leipzig, Germany
Boehringer Ingelheim Investigational Site 7
Leipzig, Germany
Boehringer Ingelheim Investigational Site 8
Leipzig, Germany
Boehringer Ingelheim Investigational Site 9
Leipzig, Germany
Boehringer Ingelheim Investigational Site
Leverkusen, Germany
Boehringer Ingelheim Investigational Site
Lichtenfels, Germany
Boehringer Ingelheim Investigational Site 1
Limburgerhof, Germany
Boehringer Ingelheim Investigational Site 2
Limburgerhof, Germany
Boehringer Ingelheim Investigational Site 1
Limburg, Germany
Boehringer Ingelheim Investigational Site 2
Limburg, Germany
Boehringer Ingelheim Investigational Site
Lingen, Germany
Boehringer Ingelheim Investigational Site
Linz, Germany
Boehringer Ingelheim Investigational Site
Lippstadt, Germany
Boehringer Ingelheim Investigational Site
Lohr, Germany
Boehringer Ingelheim Investigational Site
Ludwigsfelde, Germany
Boehringer Ingelheim Investigational Site 1
Ludwigshafen, Germany
Boehringer Ingelheim Investigational Site 2
Ludwigshafen, Germany
Boehringer Ingelheim Investigational Site
Lübbenau, Germany
Boehringer Ingelheim Investigational Site
Lübeck, Germany
Boehringer Ingelheim Investigational Site 1
Lüdenscheid, Germany
Boehringer Ingelheim Investigational Site 2
Lüdenscheid, Germany
Boehringer Ingelheim Investigational Site 1
Lüneburg, Germany
Boehringer Ingelheim Investigational Site 2
Lüneburg, Germany
Boehringer Ingelheim Investigational Site 1
Magdeburg, Germany
Boehringer Ingelheim Investigational Site 2
Magdeburg, Germany
Boehringer Ingelheim Investigational Site
Mainaschaff, Germany
Boehringer Ingelheim Investigational Site 1
Mannheim, Germany
Boehringer Ingelheim Investigational Site 2
Mannheim, Germany
Boehringer Ingelheim Investigational Site 3
Mannheim, Germany
Boehringer Ingelheim Investigational Site 4
Mannheim, Germany
Boehringer Ingelheim Investigational Site 5
Mannheim, Germany
Boehringer Ingelheim Investigational Site 6
Mannheim, Germany
Boehringer Ingelheim Investigational Site 7
Mannheim, Germany
Boehringer Ingelheim Investigational Site
Margetshöchheim, Germany
Boehringer Ingelheim Investigational Site
Markdorf, Germany
Boehringer Ingelheim Investigational Site
Markkleeberg, Germany
Boehringer Ingelheim Investigational Site 1
Marl, Germany
Boehringer Ingelheim Investigational Site 2
Marl, Germany
Boehringer Ingelheim Investigational Site
Mayen, Germany
Boehringer Ingelheim Investigational Site
Meckenheim, Germany
Boehringer Ingelheim Investigational Site
Meerbusch, Germany
Boehringer Ingelheim Investigational Site
Meinhard, Germany
Boehringer Ingelheim Investigational Site
Meißen, Germany
Boehringer Ingelheim Investigational Site
Mendig, Germany
Boehringer Ingelheim Investigational Site
Merseburg, Germany
Boehringer Ingelheim Investigational Site
Metzingen, Germany
Boehringer Ingelheim Investigational Site
Mittenwald, Germany
Boehringer Ingelheim Investigational Site
Mitterfelden, Germany
Boehringer Ingelheim Investigational Site
Molfsee, Germany
Boehringer Ingelheim Investigational Site
Monheim, Germany
Boehringer Ingelheim Investigational Site
Moormerland, Germany
Boehringer Ingelheim Investigational Site 1
Moosburg, Germany
Boehringer Ingelheim Investigational Site 2
Moosburg, Germany
Boehringer Ingelheim Investigational Site 1
Mosbach, Germany
Boehringer Ingelheim Investigational Site 2
Mosbach, Germany
Boehringer Ingelheim Investigational Site
Murrhardt, Germany
Boehringer Ingelheim Investigational Site
Mutterstadt, Germany
Boehringer Ingelheim Investigational Site 1
Mönchengladbach, Germany
Boehringer Ingelheim Investigational Site 2
Mönchengladbach, Germany
Boehringer Ingelheim Investigational Site
Mühlheim, Germany
Boehringer Ingelheim Investigational Site
Mülheim, Germany
Boehringer Ingelheim Investigational Site 10
München, Germany
Boehringer Ingelheim Investigational Site 11
München, Germany
Boehringer Ingelheim Investigational Site 1
München, Germany
Boehringer Ingelheim Investigational Site 2
München, Germany
Boehringer Ingelheim Investigational Site 3
München, Germany
Boehringer Ingelheim Investigational Site 4
München, Germany
Boehringer Ingelheim Investigational Site 5
München, Germany
Boehringer Ingelheim Investigational Site 6
München, Germany
Boehringer Ingelheim Investigational Site 7
München, Germany
Boehringer Ingelheim Investigational Site 8
München, Germany
Boehringer Ingelheim Investigational Site 9
München, Germany
Boehringer Ingelheim Investigational Site
Münchweiler, Germany
Boehringer Ingelheim Investigational Site 1
Münster, Germany
Boehringer Ingelheim Investigational Site 2
Münster, Germany
Boehringer Ingelheim Investigational Site 3
Münster, Germany
Boehringer Ingelheim Investigational Site
Nagold, Germany
Boehringer Ingelheim Investigational Site
Naundorf, Germany
Boehringer Ingelheim Investigational Site
Nettetal, Germany
Boehringer Ingelheim Investigational Site 1
Neubrandenburg, Germany
Boehringer Ingelheim Investigational Site 2
Neubrandenburg, Germany
Boehringer Ingelheim Investigational Site
Neuhaus, Germany
Boehringer Ingelheim Investigational Site
Neuhof, Germany
Boehringer Ingelheim Investigational Site
Neukirchen-Vluyn, Germany
Boehringer Ingelheim Investigational Site
Neumarkt, Germany
Boehringer Ingelheim Investigational Site 1
Neuss, Germany
Boehringer Ingelheim Investigational Site 2
Neuss, Germany
Boehringer Ingelheim Investigational Site 3
Neuss, Germany
Boehringer Ingelheim Investigational Site 1
Neustadt, Germany
Boehringer Ingelheim Investigational Site 2
Neustadt, Germany
Boehringer Ingelheim Investigational Site 3
Neustadt, Germany
Boehringer Ingelheim Investigational Site
Neustrelitz, Germany
Boehringer Ingelheim Investigational Site
Niederlehme, Germany
Boehringer Ingelheim Investigational Site
Niedernwöhren, Germany
Boehringer Ingelheim Investigational Site
Nienstädt, Germany
Boehringer Ingelheim Investigational Site
Nordstemmen, Germany
Boehringer Ingelheim Investigational Site
Nossen, Germany
Boehringer Ingelheim Investigational Site
Notzingen, Germany
Boehringer Ingelheim Investigational Site 1
Nürnberg, Germany
Boehringer Ingelheim Investigational Site 2
Nürnberg, Germany
Boehringer Ingelheim Investigational Site 1
Oberhausen, Germany
Boehringer Ingelheim Investigational Site 2
Oberhausen, Germany
Boehringer Ingelheim Investigational Site 3
Oberhausen, Germany
Boehringer Ingelheim Investigational Site
Oberkirch, Germany
Boehringer Ingelheim Investigational Site
Oer-Erkenschwick, Germany
Boehringer Ingelheim Investigational Site
Offenbach, Germany
Boehringer Ingelheim Investigational Site
Offenburg, Germany
Boehringer Ingelheim Investigational Site
Olching, Germany
Boehringer Ingelheim Investigational Site 1
Oldenburg, Germany
Boehringer Ingelheim Investigational Site 2
Oldenburg, Germany
Boehringer Ingelheim Investigational Site
Olpe, Germany
Boehringer Ingelheim Investigational Site
Oppenheim, Germany
Boehringer Ingelheim Investigational Site
Oranienburg, Germany
Boehringer Ingelheim Investigational Site 1
Osnabrück, Germany
Boehringer Ingelheim Investigational Site 2
Osnabrück, Germany
Boehringer Ingelheim Investigational Site 3
Osnabrück, Germany
Boehringer Ingelheim Investigational Site 4
Osnabrück, Germany
Boehringer Ingelheim Investigational Site
Ostrach, Germany
Boehringer Ingelheim Investigational Site
Otterbach, Germany
Boehringer Ingelheim Investigational Site
Otterndorf, Germany
Boehringer Ingelheim Investigational Site
Ottobrunn, Germany
Boehringer Ingelheim Investigational Site
Overath, Germany
Boehringer Ingelheim Investigational Site
Oy-Mittelberg, Germany
Boehringer Ingelheim Investigational Site 1
Paderborn, Germany
Boehringer Ingelheim Investigational Site 2
Paderborn, Germany
Boehringer Ingelheim Investigational Site 3
Paderborn, Germany
Boehringer Ingelheim Investigational Site 4
Paderborn, Germany
Boehringer Ingelheim Investigational Site 1
Parchim, Germany
Boehringer Ingelheim Investigational Site 2
Parchim, Germany
Boehringer Ingelheim Investigational Site
Parey, Germany
Boehringer Ingelheim Investigational Site
Passau, Germany
Boehringer Ingelheim Investigational Site 1
Peine, Germany
Boehringer Ingelheim Investigational Site 2
Peine, Germany
Boehringer Ingelheim Investigational Site
Peiting, Germany
Boehringer Ingelheim Investigational Site
Pfarrkirchen, Germany
Boehringer Ingelheim Investigational Site 1
Pforzheim, Germany
Boehringer Ingelheim Investigational Site 2
Pforzheim, Germany
Boehringer Ingelheim Investigational Site
Pirna, Germany
Boehringer Ingelheim Investigational Site
Plettenberg, Germany
Boehringer Ingelheim Investigational Site 1
Potsdam, Germany
Boehringer Ingelheim Investigational Site 2
Potsdam, Germany
Boehringer Ingelheim Investigational Site 3
Potsdam, Germany
Boehringer Ingelheim Investigational Site 4
Potsdam, Germany
Boehringer Ingelheim Investigational Site 5
Potsdam, Germany
Boehringer Ingelheim Investigational Site 6
Potsdam, Germany
Boehringer Ingelheim Investigational Site
Preetz, Germany
Boehringer Ingelheim Investigational Site
Prenzlau, Germany
Boehringer Ingelheim Investigational Site 1
Prien, Germany
Boehringer Ingelheim Investigational Site 2
Prien, Germany
Boehringer Ingelheim Investigational Site 1
Pulheim, Germany
Boehringer Ingelheim Investigational Site 2
Pulheim, Germany
Boehringer Ingelheim Investigational Site
Radeberg, Germany
Boehringer Ingelheim Investigational Site
Radevormwald, Germany
Boehringer Ingelheim Investigational Site
Rain, Germany
Boehringer Ingelheim Investigational Site 1
Rastatt, Germany
Boehringer Ingelheim Investigational Site 1
Regensburg, Germany
Boehringer Ingelheim Investigational Site 2
Regensburg, Germany
Boehringer Ingelheim Investigational Site 3
Regensburg, Germany
Boehringer Ingelheim Investigational Site 4
Regensburg, Germany
Boehringer Ingelheim Investigational Site
Regen, Germany
Boehringer Ingelheim Investigational Site
Reichenbach, Germany
Boehringer Ingelheim Investigational Site
Reinbek, Germany
Boehringer Ingelheim Investigational Site 1
Remscheid, Germany
Boehringer Ingelheim Investigational Site 2
Remscheid, Germany
Boehringer Ingelheim Investigational Site 3
Remscheid, Germany
Boehringer Ingelheim Investigational Site 4
Remscheid, Germany
Boehringer Ingelheim Investigational Site 5
Remscheid, Germany
Boehringer Ingelheim Investigational Site 6
Remscheid, Germany
Boehringer Ingelheim Investigational Site
Rendsburg, Germany
Boehringer Ingelheim Investigational Site
Rheine, Germany
Boehringer Ingelheim Investigational Site
Rodewisch, Germany
Boehringer Ingelheim Investigational Site 1
Rostock, Germany
Boehringer Ingelheim Investigational Site 2
Rostock, Germany
Boehringer Ingelheim Investigational Site 3
Rostock, Germany
Boehringer Ingelheim Investigational Site 4
Rostock, Germany
Boehringer Ingelheim Investigational Site
Röcknitz, Germany
Boehringer Ingelheim Investigational Site
Rödermark, Germany
Boehringer Ingelheim Investigational Site
Rüsselsheim, Germany
Boehringer Ingelheim Investigational Site
Saarbrücken, Germany
Boehringer Ingelheim Investigational Site
Salzgitter, Germany
Boehringer Ingelheim Investigational Site
Scharnebeck, Germany
Boehringer Ingelheim Investigational Site
Schirgiswalde, Germany
Boehringer Ingelheim Investigational Site
Schleching, Germany
Boehringer Ingelheim Investigational Site
Schleiden, Germany
Boehringer Ingelheim Investigational Site
Schleswig, Germany
Boehringer Ingelheim Investigational Site
Schloß Holte-Stukenbrock, Germany
Boehringer Ingelheim Investigational Site
Schriesheim, Germany
Boehringer Ingelheim Investigational Site
Schwaig, Germany
Boehringer Ingelheim Investigational Site
Schwalmstadt, Germany
Boehringer Ingelheim Investigational Site
Schwanewede, Germany
Boehringer Ingelheim Investigational Site
Schwarzenbach a Wald, Germany
Boehringer Ingelheim Investigational Site
Schwarzenberg, Germany
Boehringer Ingelheim Investigational Site
Schwarzenbruck, Germany
Boehringer Ingelheim Investigational Site
Schwerte, Germany
Boehringer Ingelheim Investigational Site 1
Schwäbisch Gmünd, Germany
Boehringer Ingelheim Investigational Site 2
Schwäbisch Gmünd, Germany
Boehringer Ingelheim Investigational Site
Schönebeck, Germany
Boehringer Ingelheim Investigational Site
Schönfeld, Germany
Boehringer Ingelheim Investigational Site
Seeheim-Jugenheim, Germany
Boehringer Ingelheim Investigational Site
Seifhennersdorf, Germany
Boehringer Ingelheim Investigational Site
Selbitz, Germany
Boehringer Ingelheim Investigational Site
Sendenhorst, Germany
Boehringer Ingelheim Investigational Site
Senden, Germany
Boehringer Ingelheim Investigational Site
Senftenberg, Germany
Boehringer Ingelheim Investigational Site
Siegen, Germany
Boehringer Ingelheim Investigational Site
Sigmaringen, Germany
Boehringer Ingelheim Investigational Site
Simmern, Germany
Boehringer Ingelheim Investigational Site
Sindelfingen, Germany
Boehringer Ingelheim Investigational Site
Sinsheim, Germany
Boehringer Ingelheim Investigational Site
Soest, Germany
Boehringer Ingelheim Investigational Site 1
Sondershausen, Germany
Boehringer Ingelheim Investigational Site 2
Sondershausen, Germany
Boehringer Ingelheim Investigational Site
Sonsbeck, Germany
Boehringer Ingelheim Investigational Site
Spremberg, Germany
Boehringer Ingelheim Investigational Site 1
Stade, Germany
Boehringer Ingelheim Investigational Site 2
Stade, Germany
Boehringer Ingelheim Investigational Site
Stamsried, Germany
Boehringer Ingelheim Investigational Site
Steinfeld, Germany
Boehringer Ingelheim Investigational Site
Steinmauern, Germany
Boehringer Ingelheim Investigational Site
Stendal, Germany
Boehringer Ingelheim Investigational Site
Sternberg, Germany
Boehringer Ingelheim Investigational Site
Stolberg, Germany
Boehringer Ingelheim Investigational Site
Stollberg, Germany
Boehringer Ingelheim Investigational Site
Stolpen, Germany
Boehringer Ingelheim Investigational Site
Stotternheim, Germany
Boehringer Ingelheim Investigational Site
Straelen, Germany
Boehringer Ingelheim Investigational Site
Stralsund, Germany
Boehringer Ingelheim Investigational Site
Straubing, Germany
Boehringer Ingelheim Investigational Site
Stuhr, Germany
Boehringer Ingelheim Investigational Site 10
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 11
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 1
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 2
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 3
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 4
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 5
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 6
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 7
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 8
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 9
Stuttgart, Germany
Boehringer Ingelheim Investigational Site 1
Sömmerda, Germany
Boehringer Ingelheim Investigational Site 2
Sömmerda, Germany
Boehringer Ingelheim Investigational Site
Telgte, Germany
Boehringer Ingelheim Investigational Site
Templin, Germany
Boehringer Ingelheim Investigational Site
Tirschenreuth, Germany
Boehringer Ingelheim Investigational Site 1
Trier, Germany
Boehringer Ingelheim Investigational Site 2
Trier, Germany
Boehringer Ingelheim Investigational Site 3
Trier, Germany
Boehringer Ingelheim Investigational Site
Ulm, Germany
Boehringer Ingelheim Investigational Site 1
Velen, Germany
Boehringer Ingelheim Investigational Site 2
Velen, Germany
Boehringer Ingelheim Investigational Site
Vellmar, Germany
Boehringer Ingelheim Investigational Site
Velten, Germany
Boehringer Ingelheim Investigational Site
Verden, Germany
Boehringer Ingelheim Investigational Site
Viersen, Germany
Boehringer Ingelheim Investigational Site 1
Vilshofen, Germany
Boehringer Ingelheim Investigational Site 2
Vilshofen, Germany
Boehringer Ingelheim Investigational Site 3
Vilshofen, Germany
Boehringer Ingelheim Investigational Site
Visselhövede, Germany
Boehringer Ingelheim Investigational Site
Waghäusel, Germany
Boehringer Ingelheim Investigational Site
Wahlstedt, Germany
Boehringer Ingelheim Investigational Site
Wald-Michelbach, Germany
Boehringer Ingelheim Investigational Site
Waldkraiburg, Germany
Boehringer Ingelheim Investigational Site
Wandlitz, Germany
Boehringer Ingelheim Investigational Site
Wankendorf, Germany
Boehringer Ingelheim Investigational Site
Warthausen, Germany
Boehringer Ingelheim Investigational Site
Wegberg, Germany
Boehringer Ingelheim Investigational Site
Wehrsdorf, Germany
Boehringer Ingelheim Investigational Site
Weingarten, Germany
Boehringer Ingelheim Investigational Site
Weinsberg, Germany
Boehringer Ingelheim Investigational Site
Weißenfels, Germany
Boehringer Ingelheim Investigational Site
Welbsleben, Germany
Boehringer Ingelheim Investigational Site
Welver, Germany
Boehringer Ingelheim Investigational Site
Wernigerode, Germany
Boehringer Ingelheim Investigational Site
Werningshausen, Germany
Boehringer Ingelheim Investigational Site
Wesel, Germany
Boehringer Ingelheim Investigational Site
Wessobrunn, Germany
Boehringer Ingelheim Investigational Site 1
Westoverledingen, Germany
Boehringer Ingelheim Investigational Site 2
Westoverledingen, Germany
Boehringer Ingelheim Investigational Site 1
Wiesbaden, Germany
Boehringer Ingelheim Investigational Site 2
Wiesbaden, Germany
Boehringer Ingelheim Investigational Site 3
Wiesbaden, Germany
Boehringer Ingelheim Investigational Site
Wiesenfelden, Germany
Boehringer Ingelheim Investigational Site
Wietzen, Germany
Boehringer Ingelheim Investigational Site
Wildau, Germany
Boehringer Ingelheim Investigational Site
Wilhelmshaven, Germany
Boehringer Ingelheim Investigational Site
Wilhermsdorf, Germany
Boehringer Ingelheim Investigational Site
Willich, Germany
Boehringer Ingelheim Investigational Site
Winkelhaid, Germany
Boehringer Ingelheim Investigational Site
Winsen, Germany
Boehringer Ingelheim Investigational Site 1
Wismar, Germany
Boehringer Ingelheim Investigational Site 2
Wismar, Germany
Boehringer Ingelheim Investigational Site 3
Wismar, Germany
Boehringer Ingelheim Investigational Site
Wissen, Germany
Boehringer Ingelheim Investigational Site
Wittgensdorf, Germany
Boehringer Ingelheim Investigational Site 1
Witzenhausen, Germany
Boehringer Ingelheim Investigational Site 2
Witzenhausen, Germany
Boehringer Ingelheim Investigational Site 3
Witzenhausen, Germany
Boehringer Ingelheim Investigational Site
Wolfenbüttel, Germany
Boehringer Ingelheim Investigational Site 1
Wolfratshausen, Germany
Boehringer Ingelheim Investigational Site 2
Wolfratshausen, Germany
Boehringer Ingelheim Investigational Site 3
Wolfratshausen, Germany
Boehringer Ingelheim Investigational Site
Wolfsburg, Germany
Boehringer Ingelheim Investigational Site 1
Wolgast, Germany
Boehringer Ingelheim Investigational Site
Worms, Germany
Boehringer Ingelheim Investigational Site
Wunstorf, Germany
Boehringer Ingelheim Investigational Site 1
Wuppertal, Germany
Boehringer Ingelheim Investigational Site 2
Wuppertal, Germany
Boehringer Ingelheim Investigational Site 3
Wuppertal, Germany
Boehringer Ingelheim Investigational Site 4
Wuppertal, Germany
Boehringer Ingelheim Investigational Site
Wustrau, Germany
Boehringer Ingelheim Investigational Site
Wörrstadt, Germany
Boehringer Ingelheim Investigational Site 1
Wörth, Germany
Boehringer Ingelheim Investigational Site 2
Wörth, Germany
Boehringer Ingelheim Investigational Site
Würzburg, Germany
Boehringer Ingelheim Investigational Site
Zeitz, Germany
Boehringer Ingelheim Investigational Site
Zella-Mehlis, Germany
Boehringer Ingelheim Investigational Site
Zerbst, Germany
Boehringer Ingelheim Investigational Site
Ziltendorf, Germany
Boehringer Ingelheim Investigational Site
Zirndorf, Germany
Boehringer Ingelheim Investigational Site
Zorge, Germany
Boehringer Ingelheim Investigational Site
Zschopau, Germany
Boehringer Ingelheim Investigational Site 1
Zwickau, Germany
Boehringer Ingelheim Investigational Site 2
Zwickau, Germany
Boehringer Ingelheim Investigational Site
Zwönitz, Germany
Boehringer Ingelheim Investigational Site
Übach-Palenberg, Germany
Sponsors and Collaborators
Boehringer Ingelheim
Investigators
Study Chair: Boehringer Ingelheim Boehringer Ingelheim
  More Information

Responsible Party: Boehringer Ingelheim
ClinicalTrials.gov Identifier: NCT00887289     History of Changes
Other Study ID Numbers: 248.659
First Submitted: July 29, 2008
First Posted: April 23, 2009
Results First Submitted: October 12, 2010
Results First Posted: December 15, 2010
Last Update Posted: June 27, 2014
Last Verified: March 2014

Additional relevant MeSH terms:
Syndrome
Psychomotor Agitation
Restless Legs Syndrome
Disease
Pathologic Processes
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Psychomotor Disorders
Neurobehavioral Manifestations
Signs and Symptoms
Sleep Disorders, Intrinsic
Dyssomnias
Sleep Wake Disorders
Parasomnias
Mental Disorders
Pramipexole
Antioxidants
Molecular Mechanisms of Pharmacological Action
Protective Agents
Physiological Effects of Drugs
Antiparkinson Agents
Anti-Dyskinesia Agents
Dopamine Agonists
Dopamine Agents
Neurotransmitter Agents