New Non-invasive Methods for Real-time Monitoring of Organ Function. (RTMKF)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Washington University School of Medicine
ClinicalTrials.gov Identifier:
NCT00851851
First received: February 25, 2009
Last updated: July 18, 2016
Last verified: July 2016
  Purpose
Measuring novel proteins in the urine of surgical patients that can be used to diagnose impending acute or chronic renal failure.

Condition
Acute Renal Failure
Chronic Renal Failure

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: New Non-invasive Methods for Real-time Monitoring of Organ Function.

Resource links provided by NLM:


Further study details as provided by Washington University School of Medicine:

Primary Outcome Measures:
  • To identify acute, chronic or lack of renal failure [ Time Frame: Pre-op, intraoperative, post operatively (1-6 months) ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA
Urine and blood samples

Enrollment: 641
Study Start Date: January 2009
Study Completion Date: June 2016
Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Surgical patients.
Criteria

Inclusion Criteria:

  • Patients > 18 years of age

Exclusion Criteria:

  • Patients at end stage renal disease
  • Patients dependent on dialysis at time of surgery
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00851851

Locations
United States, Missouri
Barnes Jewish Hospital
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Jerry Morrissey, PhD Washington University School of Medicine
  More Information

Responsible Party: Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00851851     History of Changes
Other Study ID Numbers: 201110033 
Study First Received: February 25, 2009
Last Updated: July 18, 2016
Health Authority: United States: Institutional Review Board

Keywords provided by Washington University School of Medicine:
Surgical patients

Additional relevant MeSH terms:
Renal Insufficiency
Kidney Failure, Chronic
Acute Kidney Injury
Kidney Diseases
Urologic Diseases
Renal Insufficiency, Chronic

ClinicalTrials.gov processed this record on August 22, 2016