Trial record 1 of 1 for:    E2905
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Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2015 by National Cancer Institute (NCI)
Sponsor:
Information provided by (Responsible Party):
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00843882
First received: February 12, 2009
Last updated: August 28, 2015
Last verified: April 2015
  Purpose

This randomized phase III trial studies lenalidomide to see how well it works with or without epoetin alfa in treating patients with myelodysplastic syndrome and anemia. Lenalidomide may stop the growth of myelodysplastic syndrome by blocking blood flow to the cells. Colony stimulating factors, such as epoetin alfa, may increase the number of immune cells found in bone marrow or peripheral blood. It is not yet known whether lenalidomide is more effective with or without epoetin alfa in treating patients with myelodysplastic syndrome and anemia.


Condition Intervention Phase
Anemia
Chronic Myelomonocytic Leukemia
de Novo Myelodysplastic Syndrome
Previously Treated Myelodysplastic Syndrome
Biological: Epoetin Alfa
Other: Laboratory Biomarker Analysis
Drug: Lenalidomide
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment With Lenalidomide (Revlimid®) Alone and in Combination With Epoetin Alfa (Procrit®) in Subjects With Low- or Intermediate-1 Risk MDS and Symptomatic Anemia

Resource links provided by NLM:


Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • MER defined as sustained transfusion independence in transfusion-dependent patients or a rise in hemoglobin > 2 g/dL in transfusion-independent patients with anemia for a minimum of 8 consecutive weeks [ Time Frame: At 16 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Bone marrow response (complete response and partial response) rate [ Time Frame: Up to 6 months ] [ Designated as safety issue: No ]
    90% confidence Interval will be calculated by treatment arm.

  • Cytogenetic response rate [ Time Frame: Up to 6 months ] [ Designated as safety issue: No ]
    Calculated by treatment arm among patients with cytogenetic abnormalities, along with its 90% confidence interval.

  • Duration of MER defined as the time interval between the documented date of MER and the earliest date of resumption of RBC transfusions >= 2 units, a reduction in hemoglobin concentration >= 2 g/dL [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
    Summarized by Kaplan-Meier method for patients who achieve MER by treatment arms.

  • Minor erythroid response rate [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
    Compared between treatment arms by Fisher's exact test.

  • Rate of MER [ Time Frame: Up to 6 months ] [ Designated as safety issue: No ]
    The 90% confidence interval of the rate of MER to salvage combination therapy will be computed in patients who fail to achieve an MER with lenalidomide monotherapy and cross over to the combination therapy.

  • Time to MER [ Time Frame: From randomization to the documented date of MER, assessed up to 16 weeks ] [ Designated as safety issue: No ]
    Time to MER will be compared between lenalidomide monotherapy and combined treatment of lenalidomide and epoetin alfa in MER responders, using a one-sided log-rank test at the significance level of 0.025.


Estimated Enrollment: 252
Study Start Date: January 2009
Estimated Primary Completion Date: April 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Arm A (lenalidomide)
Patients receive lenalidomide PO QD on days 1-21.
Other: Laboratory Biomarker Analysis
Correlative studies
Drug: Lenalidomide
Given PO
Other Names:
  • CC-5013
  • CC5013
  • CDC 501
  • LENALIDOMIDE
  • Revlimid
Experimental: Arm B (lenalidomide, epoetin alfa)
Patients receive lenalidomide PO QD on days 1-21 and epoetin alfa SC once weekly.
Biological: Epoetin Alfa
Given SC
Other Names:
  • EPO
  • Epoetin Alfa
  • Epogen
  • Eprex
  • Procrit
Other: Laboratory Biomarker Analysis
Correlative studies
Drug: Lenalidomide
Given PO
Other Names:
  • CC-5013
  • CC5013
  • CDC 501
  • LENALIDOMIDE
  • Revlimid

Detailed Description:

PRIMARY OBJECTIVES:

I. To compare the rate of major erythroid response (MER) between lenalidomide monotherapy and combined treatment of lenalidomide and epoetin alfa in erythropoietin non-responsive low-/intermediate-1 (Int-1)-risk myelodysplastic syndrome (MDS) patients or erythropoietin treatment naïve patients with low probability of erythropoietin benefit.

SECONDARY OBJECTIVES:

I. To compare the time to MER by treatment assignment. II. To evaluate the duration of MER by treatment assignment. III. To estimate the frequency of MER to salvage combination therapy in patients who fail to experience a MER with lenalidomide monotherapy.

IV. To evaluate and compare the frequency of minor erythroid response by treatment assignment.

V. To investigate the mechanism and target of lenalidomide action in patients with chromosome 5q31.1 deletion.

VI. To evaluate the frequency of cytogenetic response and progression, and the relationship between cytogenetic pattern and erythroid response.

VII. To evaluate the frequency of bone marrow response (complete response [CR] + partial response [PR]).

VIII. To evaluate the relationship between erythroid response and laboratory correlates outlined below: pretreatment and on study endogenous erythropoietin level (Arm A); to evaluate the effect of cluster of differentiation (CD)45 isoform profile on lenalidomide enhancement of erythropoietin-induced signal transducer and activator of transcription 5A (STAT5) phosphorylation in CD71^Hi erythroid precursors and the relationship to erythroid response; to characterize molecular targets relevant to lenalidomide cytotoxicity in del5q31.1 cells; to evaluate the frequency of cryptic chromosome 5q31.1 deletions in patients with non-del5q31.1 MDS by array-based genomic scan, and to determine the relationship to hematologic response.

OUTLINE: Patients are randomized to 1 of 2 treatment arms. Patients with del 5q31.1 karyotype are assigned to Arm A.

ARM A: Patients receive lenalidomide orally (PO) once daily (QD) on days 1-21.

ARM B: Patients receive lenalidomide PO QD on days 1-21 and epoetin alfa subcutaneously (SC) once weekly.

In both arms, treatment repeats every 28 days for 4 courses. Patients who achieve a major erythroid response (MER) may continue treatment beyond 4 courses in the absence of disease progression, disease conversion to acute myeloid leukemia, or unacceptable toxicity. Patients in Arm A who fail to achieve MER or who achieve MER but relapse after 16 weeks of treatment with lenalidomide may crossover and receive treatment in Arm B.

After completion of study treatment, patients are followed up for 6 months.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • NOTE: Results of the bone marrow biopsy and aspirate as well as cytogenetics are mandatory to register subjects onto study, which are indispensable to determine International Prognostic Scoring System (IPSS) category needed for eligibility; please note that it is not necessary to wait for the week 16, week 32, or week bone marrow and cytogenetic results prior to starting the next cycle unless deemed necessary by the treating physician; one example of this exception can include if the subject shows signs of progression, such as increased peripheral blood blast percentage; at that juncture, the treating physician may prefer to await the results prior to starting a new cycle; if a cycle is started, and based on the bone marrow results it is felt by the treating physician that the subject should not continue on treatment, please be sure to note this information on the case report forms at end of treatment
  • Patient must have documented diagnosis of MDS lasting at least three months (MDS duration >= 3 months) according to World Health Organization (WHO) criteria or non-proliferative chronic myelomonocytic leukemia (CMML) (white blood cell [WBC] < 12,000/mcL)
  • Patient must have IPSS categories of low- or intermediate-1-risk disease; patients must have IPSS score determined by cytogenetic analysis prior to randomization; patients must have cytogenetic analysis done (to calculate IPSS); if the current bone marrow biopsy is a dry tap, patients with cytogenetic failure and < 10% marrow blasts will be eligible; subjects with cytogenetic failure must have previous cytogenetic results (fluorescence in situ hybridization [FISH] is not a substitute) within the last 6 months post last type of MDS treatment (in this case, not referring to growth factors as type of MDS treatment)
  • Must have symptomatic anemia untransfused with hemoglobin < 9.5 g/dL =< 8 weeks prior to randomization or with red blood cells (RBC) transfusion dependence (i.e., >= 2 units/month) confirmed for =< 8 weeks before randomization

    • NOTE: For non-transfusion dependent patients (i.e., receiving < 2 units/4 weeks x 8 weeks pre-study) who receive periodic transfusions, the mean 8 week pre-transfusion hemoglobin should be used to determine protocol eligibility and response reference
    • For non-transfusion dependent patients, a minimum of 2 pre-transfusion or un-transfused hemoglobin values are required
  • Applies only for patients without the deletion 5q 31.1; patients must have failed treatment with an erythropoietic growth factor, or have a low probability of response to rhu-erythropoietin; patients with low probability of response to rhu-erythropoietin or prior erythropoietin failures are defined as follows:

    • Prior erythropoietin failure-requires a minimum trial of >= 40,000 units epoetin alfa/week x 8 weeks or equivalent dose of darbepoetin alfa for 8 weeks with failure to achieve transfusion independence in dependent patients or a failure to achieve a >= 2 g rise in hemoglobin sustained for >= 4 weeks in non-transfusion dependent patients
    • Low erythropoietin response profile-rhu-erythropoietin and epoetin alfa-naïve patients receiving >= 2U packed (p)RBC/month for a minimum of 8 weeks, and serum erythropoietin > 500 mU/mL in the 8 weeks prior to randomization for a hemoglobin < 9.5 g/dL
  • Patients must be off all non-transfusion therapy for MDS for 28 days prior to initiation of study treatment, including all types of growth factors; patients may receive hydrocortisone prophylactically to prevent transfusion reactions
  • Patients must have a serum erythropoietin level documented before randomization and =< 56 days before day 1 of study treatment; NOTE: hemoglobin must be < 9.5 g/dL at time that serum erythropoietin is drawn
  • Patients must not have documented iron deficiency; all patients must have documented marrow iron stores; if marrow iron stain is not available, the transferrin saturation must be > 20% or a serum ferritin > 100 ng/mL
  • Women must not be pregnant or breastfeeding; females of childbearing potential must have a negative serum or urine pregnancy test with a sensitivity of at least 25 mIU/mL within 10-14 days and again within 24 hours prior to starting cycle 1 of lenalidomide; a female of childbearing potential (FCBP) is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months; FCBP must also agree to ongoing pregnancy testing)
  • Effective contraception must be used by patients participating in lenalidomide therapy, and all patients must agree to counseling by a trained counselor every 28 days about pregnancy precautions and risks of fetal exposure; females of childbearing potential (FCBP) must either commit to continued abstinence from heterosexual intercourse or begin TWO acceptable methods of birth control: one highly effective method and one additional effective method AT THE SAME TIME, at least 28 days before starting lenalidomide, during lenalidomide therapy, during dose interruptions, and for at least 28 days following discontinuation of lenalidomide therapy; females of childbearing potential should be referred to a qualified provider of contraceptive methods, if needed; males receiving lenalidomide must agree to use a latex condom during any sexual contact with females of childbearing potential even if they have undergone a successful vasectomy
  • Patients must not have prior therapy with lenalidomide
  • Patients must not have a diagnosis of uncontrolled seizure or uncontrolled hypertension
  • Patients must not have proliferative (WBC >= 12,000/mcL) chronic myelomonocytic leukemia (CMML); WBC must be < 12,000/mcL
  • Patients must not have MDS secondary to treatment with radiotherapy, chemotherapy, and/or immunotherapy for malignant or autoimmune diseases
  • Platelet count >= 50,000/mcL (50 x 10^9/L) without platelet transfusion
  • Absolute neutrophil count (ANC) >= 500 cells/mcL (0.5 x 10^9/L); hence ANC must be >= 500/mcL without myeloid growth factor support
  • Serum creatinine =< 1.5 times upper limit of normal (ULN)
  • Serum glutamic oxaloacetic transaminase (SGOT)/aspartate aminotransferase (AST) or serum glutamate pyruvate transaminase (SGPT)/alanine aminotransferase (ALT) =< 2.0 x ULN
  • Serum total bilirubin < 3.0 mg/dL
  • Prior thalidomide is allowed, however, patients must not have prior >= grade-3 allergic reactions to thalidomide
  • Patients must not have prior history of desquamating rash from thalidomide at time of study entry
  • Patients must not have clinically significant anemia resulting from iron, B12 or folate deficiencies, autoimmune or hereditary hemolysis, or gastrointestinal bleeding
  • Patients must not have used cytotoxic chemotherapeutic agents or experimental agents (agents that are not commercially available) for the treatment of MDS within 8 weeks of randomization
  • Patients must not have prior history of malignancy other than MDS (except basal cell or squamous skin cell carcinoma or carcinoma in situ of the cervix or breast) unless the subject has been confirmed free of disease for >= 3 years
  • Patients must not have any serious medical condition or any other unstable medical co-morbidity, or psychiatric illness that will prevent the subject from signing the informed consent form or will place the subject at unacceptable risk if he/she participates in the study
  • Patients must not have a history of thrombo-embolic events within 3 years prior to study randomization
  • Patients must not have known human immunodeficiency virus (HIV)-1 seropositivity
  • Patients must not have a known allergic reaction to epoetin alfa (Procrit) or human serum albumin
  • Eligibility for crossover registration from Arm A (lenalidomide alone) to Arm B (lenalidomide and epoetin alfa):
  • Patients must have completed 16 weeks of monotherapy with lenalidomide
  • Patients must show failure to achieve MER (major erythroid response) or have achieved MER but relapsed on Arm A
  • Patients must not have a limiting unresolved grade 3 or greater toxicity from lenalidomide monotherapy or drug intolerance preventing continuation of lenalidomide treatment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00843882

  Hide Study Locations
Locations
United States, Alabama
University of Alabama at Birmingham Cancer Center Recruiting
Birmingham, Alabama, United States, 35233
Contact: Uma M. Borate    205-934-0309      
Principal Investigator: Uma M. Borate         
United States, Alaska
Fairbanks Memorial Hospital Active, not recruiting
Fairbanks, Alaska, United States, 99701
United States, Arizona
Mayo Clinic in Arizona Recruiting
Scottsdale, Arizona, United States, 85259
Contact: Mark R. Litzow    507-538-7623      
Principal Investigator: Mark R. Litzow         
The University of Arizona Cancer Center-North Campus Withdrawn
Tucson, Arizona, United States, 85719
The University of Arizona Medical Center-University Campus Withdrawn
Tucson, Arizona, United States, 85724
United States, California
Kaiser Permanente-Anaheim Active, not recruiting
Anaheim, California, United States, 92807
Kaiser Permanente-Baldwin Park Recruiting
Baldwin Park, California, United States, 91706
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Kaiser Permanente-Bellflower Active, not recruiting
Bellflower, California, United States, 90706
Kaiser Permanente Hospital Active, not recruiting
Fontana, California, United States, 92335
Marin Cancer Care Inc Recruiting
Greenbrae, California, United States, 94904
Contact: Peter D. Eisenberg    415-925-5000    info@marinspecialtycare.com   
Principal Investigator: Peter D. Eisenberg         
Kaiser Permanente - Harbor City Active, not recruiting
Harbor City, California, United States, 90710
Kaiser Permanente-Irvine Recruiting
Irvine, California, United States, 92618
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Kaiser Permanente-Cadillac Active, not recruiting
Los Angeles, California, United States, 90034
Kaiser Permanente Los Angeles Medical Center Recruiting
Los Angeles, California, United States, 90027
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Fremont - Rideout Cancer Center Active, not recruiting
Marysville, California, United States, 95901
Stanford Cancer Institute Withdrawn
Palo Alto, California, United States, 94304
Kaiser Permanente - Panorama City Recruiting
Panorama City, California, United States, 91402
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Kaiser Permanente-Riverside Active, not recruiting
Riverside, California, United States, 92505
University of California Davis Comprehensive Cancer Center Recruiting
Sacramento, California, United States, 95817
Contact: Jeanna L. Welborn    916-734-3089      
Principal Investigator: Jeanna L. Welborn         
Saint Helena Hospital Withdrawn
Saint Helena, California, United States, 94574
Kaiser Permanente-San Diego Mission Recruiting
San Diego, California, United States, 92108
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Kaiser Permanente-San Diego Zion Recruiting
San Diego, California, United States, 92120
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Kaiser Permanente-San Marcos Recruiting
San Marcos, California, United States, 92069
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
Presbyterian Intercommunity Hospital Active, not recruiting
Whittier, California, United States, 90602
Kaiser Permanente Recruiting
Woodland Hills, California, United States, 91367
Contact: Han A. Koh    626-564-3455      
Principal Investigator: Han A. Koh         
United States, Colorado
The Medical Center of Aurora Active, not recruiting
Aurora, Colorado, United States, 80012
Boulder Community Hospital Active, not recruiting
Boulder, Colorado, United States, 80301
Penrose-Saint Francis Healthcare Active, not recruiting
Colorado Springs, Colorado, United States, 80907
Rocky Mountain Cancer Centers-Penrose Active, not recruiting
Colorado Springs, Colorado, United States, 80907
Rose Medical Center Active, not recruiting
Denver, Colorado, United States, 80220
Colorado Blood Cancer Institute Active, not recruiting
Denver, Colorado, United States, 80218
Exempla Saint Joseph Hospital Active, not recruiting
Denver, Colorado, United States, 80218
Porter Adventist Hospital Active, not recruiting
Denver, Colorado, United States, 80210
Presbyterian - Saint Lukes Medical Center - Health One Active, not recruiting
Denver, Colorado, United States, 80218
Rocky Mountain Cancer Centers-Midtown Active, not recruiting
Denver, Colorado, United States, 80218
Rocky Mountain Cancer Centers-Rose Active, not recruiting
Denver, Colorado, United States, 80220
Colorado Cancer Research Program CCOP Recruiting
Denver, Colorado, United States, 80224-2522
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Mercy Medical Center Active, not recruiting
Durango, Colorado, United States, 81301
Comprehensive Cancer Care and Research Institute of Colorado LLC Active, not recruiting
Englewood, Colorado, United States, 80113
Swedish Medical Center Active, not recruiting
Englewood, Colorado, United States, 80113
Poudre Valley Hospital Recruiting
Fort Collins, Colorado, United States, 80524
Contact: Steven R. Schuster    507-538-7623      
Principal Investigator: Steven R. Schuster         
Mountain Blue Cancer Care Center Active, not recruiting
Golden, Colorado, United States, 80401
Saint Mary's Hospital and Regional Medical Center Active, not recruiting
Grand Junction, Colorado, United States, 81502
North Colorado Medical Center Active, not recruiting
Greeley, Colorado, United States, 80631
Rocky Mountain Cancer Centers-Greenwood Village Active, not recruiting
Greenwood Village, Colorado, United States, 80111
Rocky Mountain Cancer Centers-Lakewood Active, not recruiting
Lakewood, Colorado, United States, 80228
Saint Anthony Hospital Active, not recruiting
Lakewood, Colorado, United States, 80228
Littleton Adventist Hospital Active, not recruiting
Littleton, Colorado, United States, 80122
Rocky Mountain Cancer Centers-Sky Ridge Active, not recruiting
Lone Tree, Colorado, United States, 80124
Sky Ridge Medical Center Active, not recruiting
Lone Tree, Colorado, United States, 80124
Longmont United Hospital Active, not recruiting
Longmont, Colorado, United States, 80501
McKee Medical Center Active, not recruiting
Loveland, Colorado, United States, 80539
Rocky Mountain Cancer Centers-Parker Active, not recruiting
Parker, Colorado, United States, 80138
Parker Adventist Hospital Active, not recruiting
Parker, Colorado, United States, 80138
Saint Mary Corwin Medical Center Active, not recruiting
Pueblo, Colorado, United States, 81004
North Suburban Medical Center Terminated
Thornton, Colorado, United States, 80229
SCL Health Lutheran Medical Center Active, not recruiting
Wheat Ridge, Colorado, United States, 80033
United States, Connecticut
University of Connecticut Active, not recruiting
Farmington, Connecticut, United States, 06030
Saint Francis Hospital and Medical Center Recruiting
Hartford, Connecticut, United States, 06105
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
The Hospital of Central Connecticut Active, not recruiting
New Britain, Connecticut, United States, 06050
Yale University Recruiting
New Haven, Connecticut, United States, 06520
Contact: Steven D. Gore    203-785-5702      
Principal Investigator: Steven D. Gore         
United States, Delaware
Beebe Medical Center Recruiting
Lewes, Delaware, United States, 19958
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Christiana Care Health System-Christiana Hospital Recruiting
Newark, Delaware, United States, 19718
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Delaware Clinical and Laboratory Physicians PA Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Regional Hematology and Oncology PA Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Medical Oncology Hematology Consultants PA Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Helen F Graham Cancer Center Recruiting
Newark, Delaware, United States, 19713
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Beebe Health Campus Recruiting
Rehoboth Beach, Delaware, United States, 19971
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
Nanticoke Memorial Hospital Recruiting
Seaford, Delaware, United States, 19973
Contact: Gregory A. Masters    302-733-6227      
Principal Investigator: Gregory A. Masters         
United States, Florida
Holy Cross Hospital Terminated
Fort Lauderdale, Florida, United States, 33308
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Recruiting
Hollywood, Florida, United States, 33021
Contact: Daren D. Grosman    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Daren D. Grosman         
Baptist Cancer Institute Recruiting
Jacksonville, Florida, United States, 32207
Contact: Troy H. Guthrie    904-202-7051      
Principal Investigator: Troy H. Guthrie         
Mayo Clinic in Florida Recruiting
Jacksonville, Florida, United States, 32224-9980
Contact: Mark R. Litzow    507-538-7623      
Principal Investigator: Mark R. Litzow         
Jupiter Medical Center Terminated
Jupiter, Florida, United States, 33458
Leesburg Regional Medical Center Recruiting
Leesburg, Florida, United States, 34748
Contact: Pablo C. Reyes       info@cfhalliance.org   
Principal Investigator: Pablo C. Reyes         
Baptist Hospital of Miami Active, not recruiting
Miami, Florida, United States, 33176
University of Miami Miller School of Medicine-Sylvester Cancer Center Active, not recruiting
Miami, Florida, United States, 33136
Mount Sinai Medical Center Recruiting
Miami Beach, Florida, United States, 33140
Contact: Michael A. Schwartz    305-674-2625    info@msccop.com   
Principal Investigator: Michael A. Schwartz         
Moffitt Cancer Center Recruiting
Tampa, Florida, United States, 33612
Contact: Alan F. List    800-456-7121    canceranswers@moffitt.org   
Principal Investigator: Alan F. List         
United States, Georgia
Georgia Regents University Medical Center Active, not recruiting
Augusta, Georgia, United States, 30912
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise Recruiting
Boise, Idaho, United States, 83706
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Saint Luke's Mountain States Tumor Institute Recruiting
Boise, Idaho, United States, 83712
Contact: Paul G. Montgomery    800-845-4624      
Principal Investigator: Paul G. Montgomery         
Saint Luke's Mountain States Tumor Institute - Fruitland Recruiting
Fruitland, Idaho, United States, 83619
Contact: Paul G. Montgomery    800-845-4624      
Principal Investigator: Paul G. Montgomery         
Saint Luke's Mountain States Tumor Institute - Meridian Recruiting
Meridian, Idaho, United States, 83642
Contact: Paul G. Montgomery    800-845-4624      
Principal Investigator: Paul G. Montgomery         
Saint Luke's Mountain States Tumor Institute - Nampa Recruiting
Nampa, Idaho, United States, 83686
Contact: Paul G. Montgomery    800-845-4624      
Principal Investigator: Paul G. Montgomery         
Kootenai Cancer Center Recruiting
Post Falls, Idaho, United States, 83854
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Saint Luke's Mountain States Tumor Institute-Twin Falls Recruiting
Twin Falls, Idaho, United States, 83301
Contact: Paul G. Montgomery    800-845-4624      
Principal Investigator: Paul G. Montgomery         
United States, Illinois
Illinois CancerCare-Bloomington Recruiting
Bloomington, Illinois, United States, 61704
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Canton Recruiting
Canton, Illinois, United States, 61520
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Carthage Recruiting
Carthage, Illinois, United States, 62321
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Hematology and Oncology Associates Terminated
Chicago, Illinois, United States, 60611
Northwestern University Recruiting
Chicago, Illinois, United States, 60611
Contact: Olga Frankfurt    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Olga Frankfurt         
Presence Resurrection Medical Center Recruiting
Chicago, Illinois, United States, 60631
Contact: Christopher G. Rose    773-792-5116      
Principal Investigator: Christopher G. Rose         
University of Chicago Comprehensive Cancer Center Active, not recruiting
Chicago, Illinois, United States, 60637
Weiss Memorial Hospital Recruiting
Chicago, Illinois, United States, 60640
Contact: Stuart A. Krauss    773-564-5044      
Principal Investigator: Stuart A. Krauss         
Cancer Care Center of Decatur Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Elmhurst Memorial Hospital Recruiting
Elmhurst, Illinois, United States, 60126
Contact: Lucio Di Nunno    630-782-7900    Jrohde@emhc.org   
Principal Investigator: Lucio Di Nunno         
Illinois CancerCare-Eureka Recruiting
Eureka, Illinois, United States, 61530
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
NorthShore University HealthSystem-Evanston Hospital Recruiting
Evanston, Illinois, United States, 60201
Contact: David L. Grinblatt    847-570-2109      
Principal Investigator: David L. Grinblatt         
Saint Francis Hospital Active, not recruiting
Evanston, Illinois, United States, 60202
NorthShore University HealthSystem-Glenbrook Hospital Recruiting
Glenview, Illinois, United States, 60026
Contact: David L. Grinblatt    847-570-2109      
Principal Investigator: David L. Grinblatt         
Hematology Oncology Associates of Illinois-Highland Park Active, not recruiting
Highland Park, Illinois, United States, 60035
NorthShore University HealthSystem-Highland Park Hospital Recruiting
Highland Park, Illinois, United States, 60035
Contact: David L. Grinblatt    847-570-2109      
Principal Investigator: David L. Grinblatt         
Joliet Oncology-Hematology Associates Limited Recruiting
Joliet, Illinois, United States, 60435
Contact: Kulumani M. Sivarajan    815-730-3098    maureenc@jolietoncology.com   
Principal Investigator: Kulumani M. Sivarajan         
Midwest Center for Hematology Oncology Terminated
Joliet, Illinois, United States, 60432
Presence Saint Mary's Hospital Active, not recruiting
Kankakee, Illinois, United States, 60901
Illinois CancerCare-Kewanee Clinic Recruiting
Kewanee, Illinois, United States, 61443
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
NorthShore Hematology Oncology-Libertyville Active, not recruiting
Libertyville, Illinois, United States, 60048
Illinois CancerCare-Macomb Recruiting
Macomb, Illinois, United States, 61455
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois Cancer Specialists-Niles Active, not recruiting
Niles, Illinois, United States, 60714
Illinois CancerCare-Ottawa Clinic Recruiting
Ottawa, Illinois, United States, 61350
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Pekin Recruiting
Pekin, Illinois, United States, 61554
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Peru Recruiting
Peru, Illinois, United States, 61354
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Illinois CancerCare-Princeton Recruiting
Princeton, Illinois, United States, 61356
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
SwedishAmerican Regional Cancer Center/ACT Recruiting
Rockford, Illinois, United States, 61114
Contact: Harvey E. Einhorn    779-696-9400    cancercare@swedishamerican.org   
Principal Investigator: Harvey E. Einhorn         
Swedish American Hospital Withdrawn
Rockford, Illinois, United States, 61104
Hematology Oncology Associates of Illinois - Skokie Active, not recruiting
Skokie, Illinois, United States, 60076
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Southern Illinois University School of Medicine Recruiting
Springfield, Illinois, United States, 62702
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Springfield Clinic Recruiting
Springfield, Illinois, United States, 62703
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Central Illinois Hematology Oncology Center Recruiting
Springfield, Illinois, United States, 62702
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Cadence Cancer Center in Warrenville Active, not recruiting
Warrenville, Illinois, United States, 60555
United States, Indiana
Franciscan St. Francis Health-Beech Grove Withdrawn
Beech Grove, Indiana, United States, 46107
Michiana Hematology Oncology PC-Elkhart Recruiting
Elkhart, Indiana, United States, 46514
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Elkhart Clinic Terminated
Elkhart, Indiana, United States, 46514-2098
Elkhart General Hospital Terminated
Elkhart, Indiana, United States, 46515
Fort Wayne Medical Oncology and Hematology Inc-Parkview Withdrawn
Fort Wayne, Indiana, United States, 46845
IU Health Central Indiana Cancer Centers-East Recruiting
Indianapolis, Indiana, United States, 46219
Contact: Hillary H. Wu    317-356-2422      
Principal Investigator: Hillary H. Wu         
Community Howard Regional Health Terminated
Kokomo, Indiana, United States, 46904
IU Health La Porte Hospital Terminated
La Porte, Indiana, United States, 46350
IU Health Arnett Cancer Care Recruiting
Lafayette, Indiana, United States, 47904
Contact: Thomas I. Jones    765-838-6871    thimes@iuhealth.org   
Principal Investigator: Thomas I. Jones         
Premier Oncology Hematology Associates Active, not recruiting
Merrillville, Indiana, United States, 46410
Michiana Hematology Oncology PC-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Saint Joseph Regional Medical Center-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Michiana Hematology Oncology PC-Plymouth Recruiting
Plymouth, Indiana, United States, 46563
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Reid Hospital and Health Care Services Active, not recruiting
Richmond, Indiana, United States, 47374
Northern Indiana Cancer Research Consortium CCOP Recruiting
South Bend, Indiana, United States, 46628
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Michiana Hematology Oncology PC-South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Memorial Hospital of South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Thomas J. Reid    800-284-7370      
Principal Investigator: Thomas J. Reid         
South Bend Clinic Terminated
South Bend, Indiana, United States, 46617
Michiana Hematology Oncology PC-Westville Recruiting
Westville, Indiana, United States, 46391
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
United States, Iowa
McFarland Clinic PC-William R Bliss Cancer Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Cedar Rapids Oncology Association Terminated
Cedar Rapids, Iowa, United States, 52403
Mercy Hospital Active, not recruiting
Cedar Rapids, Iowa, United States, 52403
Oncology Associates at Mercy Medical Center Active, not recruiting
Cedar Rapids, Iowa, United States, 52403
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Iowa Lutheran Hospital Active, not recruiting
Des Moines, Iowa, United States, 50316
Iowa Methodist Medical Center Active, not recruiting
Des Moines, Iowa, United States, 50309
Iowa Oncology Research Association CCOP Active, not recruiting
Des Moines, Iowa, United States, 50309
Medical Oncology and Hematology Associates-Des Moines Active, not recruiting
Des Moines, Iowa, United States, 50309
Mercy Medical Center - Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Mercy Capitol Terminated
Des Moines, Iowa, United States, 50307
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Mercy Medical Center - North Iowa Recruiting
Mason City, Iowa, United States, 50401
Contact: Arvind Y. Vemula    800-433-3883      
Principal Investigator: Arvind Y. Vemula         
Ottumwa Regional Health Center Recruiting
Ottumwa, Iowa, United States, 52501
Contact: Praveen Vikas    641-684-2742      
Principal Investigator: Praveen Vikas         
Saint Luke's Regional Medical Center Terminated
Sioux City, Iowa, United States, 51104
Siouxland Regional Cancer Center Recruiting
Sioux City, Iowa, United States, 51101
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Mercy Medical Center-Sioux City Terminated
Sioux City, Iowa, United States, 51104
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
United States, Kansas
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Saint Luke's South Hospital Active, not recruiting
Overland Park, Kansas, United States, 66213
Menorah Medical Center Active, not recruiting
Overland Park, Kansas, United States, 66209
Kansas City CCOP Terminated
Prairie Village, Kansas, United States, 66208
Shawnee Mission Medical Center-KCCC Terminated
Shawnee Mission, Kansas, United States, 66204
Wesley Medical Center Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
United States, Kentucky
King's Daughter's Medical Center Active, not recruiting
Ashland, Kentucky, United States, 41101
Jewish Hospital Recruiting
Louisville, Kentucky, United States, 40202
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Jewish Hospital Medical Center Northeast Recruiting
Louisville, Kentucky, United States, 40245
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
United States, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting
Baltimore, Maryland, United States, 21287
Contact: Amy E. DeZern    410-955-8804    jhcccro@jhmi.edu   
Principal Investigator: Amy E. DeZern         
Saint Agnes Hospital Recruiting
Baltimore, Maryland, United States, 21229
Contact: Carole B. Miller    410-368-2910      
Principal Investigator: Carole B. Miller         
University of Maryland/Greenebaum Cancer Center Withdrawn
Baltimore, Maryland, United States, 21201
Walter Reed National Military Medical Center Recruiting
Bethesda, Maryland, United States, 20889-5600
Contact: Corey A. Carter    800-411-1222      
Principal Investigator: Corey A. Carter         
Union Hospital of Cecil County Active, not recruiting
Elkton MD, Maryland, United States, 21921
Frederick Memorial Hospital Withdrawn
Frederick, Maryland, United States, 21701
United States, Massachusetts
Steward Saint Elizabeth's Medical Center Withdrawn
Brighton, Massachusetts, United States, 02135-2997
Lahey Hospital and Medical Center Recruiting
Burlington, Massachusetts, United States, 01805
Contact: Alan F. List    813-745-7101    alan.list@moffitt.org   
Principal Investigator: Alan F. List         
Holy Family Hospital Withdrawn
Methuen, Massachusetts, United States, 01844
University of Massachusetts Medical School Withdrawn
Worcester, Massachusetts, United States, 01655
United States, Michigan
Bixby Medical Center Withdrawn
Adrian, Michigan, United States, 49221
Hickman Cancer Center Withdrawn
Adrian, Michigan, United States, 49221
Michigan Cancer Research Consortium CCOP Terminated
Ann Arbor, Michigan, United States, 48106
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106-0995
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
University of Michigan Comprehensive Cancer Center Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Dale L. Bixby    800-865-1125      
Principal Investigator: Dale L. Bixby         
Oakwood Hospital and Medical Center Recruiting
Dearborn, Michigan, United States, 48124
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Wayne State University/Karmanos Cancer Institute Recruiting
Detroit, Michigan, United States, 48201
Contact: Charles A. Schiffer    313-576-9363      
Principal Investigator: Charles A. Schiffer         
Green Bay Oncology - Escanaba Recruiting
Escanaba, Michigan, United States, 49431
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Genesys Regional Medical Center-West Flint Campus Terminated
Flint, Michigan, United States, 48532
Hurley Medical Center Active, not recruiting
Flint, Michigan, United States, 48502
Green Bay Oncology - Iron Mountain Recruiting
Iron Mountain, Michigan, United States, 49801
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Allegiance Health Recruiting
Jackson, Michigan, United States, 49201
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Borgess Medical Center Active, not recruiting
Kalamazoo, Michigan, United States, 49001
Bronson Methodist Hospital Active, not recruiting
Kalamazoo, Michigan, United States, 49007
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Sunil Nagpal    269-373-7458      
Principal Investigator: Sunil Nagpal         
Sparrow Hospital Active, not recruiting
Lansing, Michigan, United States, 48912
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Marquette General Hospital Recruiting
Marquette, Michigan, United States, 49855
Contact: Amy M. Weise    313-576-9363      
Principal Investigator: Amy M. Weise         
Mercy Memorial Hospital Withdrawn
Monroe, Michigan, United States, 48162
Toledo Clinic Cancer Centers-Monroe Withdrawn
Monroe, Michigan, United States, 48162
Michiana Hematology Oncology PC-Niles Terminated
Niles, Michigan, United States, 49120
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Port Huron Recruiting
Port Huron, Michigan, United States, 48060
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
Marie Yeager Cancer Center Withdrawn
Saint Joseph, Michigan, United States, 49085
Providence Hospital-Southfield Cancer Center Recruiting
Southfield, Michigan, United States, 48075
Contact: Howard R. Terebelo    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Howard R. Terebelo         
Lakeland Hospital Recruiting
St. Joseph, Michigan, United States, 49085
Contact: Bilal Ansari    574-237-1328      
Principal Investigator: Bilal Ansari         
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Philip J. Stella    734-712-4673      
Principal Investigator: Philip J. Stella         
United States, Minnesota
Medini, Eitan MD (UIA Investigator) Terminated
Alexandria, Minnesota, United States, 56308
Fairview Ridges Hospital Recruiting
Burnsville, Minnesota, United States, 55337
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Essentia Health Cancer Center Recruiting
Duluth, Minnesota, United States, 55805
Contact: Bret E. Friday    888-203-7267      
Principal Investigator: Bret E. Friday         
Fairview-Southdale Hospital Recruiting
Edina, Minnesota, United States, 55435
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Unity Hospital Recruiting
Fridley, Minnesota, United States, 55432
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Hutchinson Area Health Care Recruiting
Hutchinson, Minnesota, United States, 55350
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Saint John's Hospital - Healtheast Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Minnesota Oncology Hematology PA-Maplewood Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Health Partners Inc Recruiting
Minneapolis, Minnesota, United States, 55454
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Minneapolis Veterans Medical Center Withdrawn
Minneapolis, Minnesota, United States, 55417
North Memorial Medical Health Center Recruiting
Robbinsdale, Minnesota, United States, 55422
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Mayo Clinic Recruiting
Rochester, Minnesota, United States, 55905
Contact: Mark R. Litzow    507-538-7623      
Principal Investigator: Mark R. Litzow         
Coborn Cancer Center at Saint Cloud Hospital Recruiting
Saint Cloud, Minnesota, United States, 56303
Contact: Donald J. Jurgens    877-229-4907    coborncancercenter@centracare.com   
Principal Investigator: Donald J. Jurgens         
Saint Cloud Hospital Active, not recruiting
Saint Cloud, Minnesota, United States, 56303
Metro-Minnesota NCI Community Oncology Research Program Terminated
Saint Louis Park, Minnesota, United States, 55416
Park Nicollet Clinic - Saint Louis Park Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Saint Francis Regional Medical Center Recruiting
Shakopee, Minnesota, United States, 55379
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Lakeview Hospital Active, not recruiting
Stillwater, Minnesota, United States, 55082
Ridgeview Medical Center Recruiting
Waconia, Minnesota, United States, 55387
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Minnesota Oncology and Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
United States, Mississippi
Keesler Medical Center Withdrawn
Kessler AFB, Mississippi, United States, 39534
Singing River Hospital Withdrawn
Pascagoula, Mississippi, United States, 39581
United States, Missouri
Saint Francis Medical Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Southeast Cancer Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
University of Missouri - Ellis Fischel Recruiting
Columbia, Missouri, United States, 65212
Contact: Clint D. Kingsley    573-882-7440      
Principal Investigator: Clint D. Kingsley         
Capital Region Medical Center-Goldschmidt Cancer Center Recruiting
Jefferson City, Missouri, United States, 65109
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Truman Medical Center Active, not recruiting
Kansas City, Missouri, United States, 64108
Kansas City Veterans Affairs Medical Center Active, not recruiting
Kansas City, Missouri, United States, 64128
North Kansas City Hospital Active, not recruiting
Kansas City, Missouri, United States, 64116
Research Medical Center Active, not recruiting
Kansas City, Missouri, United States, 64132
Saint Joseph Health Center Terminated
Kansas City, Missouri, United States, 64114
Saint Luke's Cancer Institute Terminated
Kansas City, Missouri, United States, 64111
Saint Luke's Hospital of Kansas City Recruiting
Kansas City, Missouri, United States, 64111
Contact: Rakesh Gaur    816-932-2677    SLCIResearch1@saint-lukes.org   
Principal Investigator: Rakesh Gaur         
Heartland Hematology and Oncology Associates Incorporated Active, not recruiting
Kansas City, Missouri, United States, 64118
Saint Luke's East - Lee's Summit Active, not recruiting
Lee's Summit, Missouri, United States, 64086
Liberty Hospital Withdrawn
Liberty, Missouri, United States, 64068
Liberty Radiation Oncology Center Active, not recruiting
Liberty, Missouri, United States, 64068
Heartland Regional Medical Center Active, not recruiting
Saint Joseph, Missouri, United States, 64506
Saint Joseph Oncology Inc Terminated
Saint Joseph, Missouri, United States, 64507
Center for Cancer Care and Research Terminated
Saint Louis, Missouri, United States, 63141
Comprehensive Cancer Care PC Terminated
Saint Louis, Missouri, United States, 63141
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Saint Anthony's Medical Center Recruiting
Saint Louis, Missouri, United States, 63128
Contact: Minxiang (Michael) Gu    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Minxiang (Michael) Gu         
Mercy Hospital Springfield Active, not recruiting
Springfield, Missouri, United States, 65804
United States, Montana
Saint Vincent Healthcare Active, not recruiting
Billings, Montana, United States, 59101
Frontier Cancer Center and Blood Institute-Billings Terminated
Billings, Montana, United States, 59102
Montana Cancer Consortium CCOP Active, not recruiting
Billings, Montana, United States, 59101
Northern Rockies Radiation Oncology Center Terminated
Billings, Montana, United States, 59101
Billings Clinic Cancer Center Recruiting
Billings, Montana, United States, 59107
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Cancer Center Withdrawn
Bozeman, Montana, United States, 59715
Saint James Community Hospital and Cancer Treatment Center Recruiting
Butte, Montana, United States, 59701
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Great Falls Clinic Terminated
Great Falls, Montana, United States, 59405
Berdeaux, Donald MD (UIA Investigator) Terminated
Great Falls, Montana, United States, 59405
Benefis Healthcare- Sletten Cancer Institute Recruiting
Great Falls, Montana, United States, 59405
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Northern Montana Hospital Terminated
Havre, Montana, United States, 59501
Saint Peter's Community Hospital Active, not recruiting
Helena, Montana, United States, 59601
Glacier Oncology PLLC Terminated
Kalispell, Montana, United States, 59901
Kalispell Medical Oncology Terminated
Kalispell, Montana, United States, 59901
Kalispell Regional Medical Center Active, not recruiting
Kalispell, Montana, United States, 59901
Guardian Oncology and Center for Wellness Terminated
Missoula, Montana, United States, 59804
Community Medical Hospital Active, not recruiting
Missoula, Montana, United States, 59801
Montana Cancer Specialists Terminated
Missoula, Montana, United States, 59802
Saint Patrick Hospital - Community Hospital Active, not recruiting
Missoula, Montana, United States, 59802
United States, Nebraska
CHI Health Saint Francis Recruiting
Grand Island, Nebraska, United States, 68803
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
CHI Health Good Samaritan Recruiting
Kearney, Nebraska, United States, 68847
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Nebraska Cancer Research Center Recruiting
Lincoln, Nebraska, United States, 68510
Contact: Gamini S. Soori    402-991-8070    mwilwerding@mvcc.cc   
Principal Investigator: Gamini S. Soori         
Alegent Health Bergan Mercy Medical Center Active, not recruiting
Omaha, Nebraska, United States, 68124
Alegent Health Immanuel Medical Center Active, not recruiting
Omaha, Nebraska, United States, 68122
Creighton University Medical Center Active, not recruiting
Omaha, Nebraska, United States, 68131
Missouri Valley Cancer Consortium Active, not recruiting
Omaha, Nebraska, United States, 68106
University of Nebraska Medical Center Recruiting
Omaha, Nebraska, United States, 68198
Contact: Lori J. Maness-Harris    402-559-6941    unmcrsa@unmc.edu   
Principal Investigator: Lori J. Maness-Harris         
United States, Nevada
University Medical Center of Southern Nevada Active, not recruiting
Las Vegas, Nevada, United States, 89102
Nevada Cancer Research Foundation CCOP Recruiting
Las Vegas, Nevada, United States, 89106
Contact: John A. Ellerton    702-384-0013      
Principal Investigator: John A. Ellerton         
Cancer and Blood Specialists-Fort Apache Recruiting
Las Vegas, Nevada, United States, 89148
Contact: John A. Ellerton    702-384-0013      
Principal Investigator: John A. Ellerton         
United States, New Hampshire
Cheshire Medical Center-Dartmouth-Hitchcock Keene Recruiting
Keene, New Hampshire, United States, 03431
Contact: James M. Nickerson    603-354-5454 ext 2155    jmichelson@cheshire-med.com   
Principal Investigator: James M. Nickerson         
United States, New Jersey
Cooper Hospital University Medical Center Recruiting
Camden, New Jersey, United States, 08103
Contact: Neil A. Lachant    856-325-6757      
Principal Investigator: Neil A. Lachant         
Veterans Adminstration New Jersey Health Care System Recruiting
East Orange, New Jersey, United States, 07018-1095
Contact: Victor T. Chang    800-475-2336    patricia.goyer@med.va.gov   
Principal Investigator: Victor T. Chang         
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County Withdrawn
Mount Holly, New Jersey, United States, 08060
Jersey Shore Medical Center Active, not recruiting
Neptune, New Jersey, United States, 07753
Newark Beth Israel Medical Center Recruiting
Newark, New Jersey, United States, 07112
Contact: Lori Schleicher    973-926-7230      
Principal Investigator: Lori Schleicher         
Riverview Medical Center/Booker Cancer Center Active, not recruiting
Red Bank, New Jersey, United States, 07701
Community Medical Center Active, not recruiting
Toms River, New Jersey, United States, 08755
Inspira Medical Center Vineland Recruiting
Vineland, New Jersey, United States, 08360
Contact: Tami L. Bach    856-641-7933      
Principal Investigator: Tami L. Bach         
Virtua West Jersey Hospital Voorhees Withdrawn
Voorhees, New Jersey, United States, 08043
Inspira Medical Center Woodbury Recruiting
Woodbury, New Jersey, United States, 08096
Contact: Tami L. Bach    856-641-7933      
Principal Investigator: Tami L. Bach         
United States, New York
Albert Einstein College of Medicine Recruiting
Bronx, New York, United States, 10461
Contact: Amit K. Verma    718-904-2730    aecc@aecom.yu.edu   
Principal Investigator: Amit K. Verma         
Montefiore Medical Center - Moses Campus Recruiting
Bronx, New York, United States, 10467-2490
Contact: Amit K. Verma    718-904-2730    aecc@aecom.yu.edu   
Principal Investigator: Amit K. Verma         
Hematology Oncology Associates of Central New York-East Syracuse Active, not recruiting
East Syracuse, New York, United States, 13057
Glens Falls Hospital Active, not recruiting
Glens Falls, New York, United States, 12801
Orange Regional Medical Center Active, not recruiting
Middletown, New York, United States, 10940
Winthrop University Hospital Recruiting
Mineola, New York, United States, 11501
Contact: Harry Staszewski    866-946-8476      
Principal Investigator: Harry Staszewski         
Laura and Issac Perlmutter Cancer Center at NYU Langone Recruiting
New York, New York, United States, 10016
Contact: Bruce G. Raphael    212-263-4434    prmc.coordinator@nyumc.org   
Principal Investigator: Bruce G. Raphael         
Memorial Sloan-Kettering Cancer Center Active, not recruiting
New York, New York, United States, 10065
Highland Hospital Active, not recruiting
Rochester, New York, United States, 14620
University of Rochester Recruiting
Rochester, New York, United States, 14642
Contact: Jonathan W. Friedberg    585-275-5830      
Principal Investigator: Jonathan W. Friedberg         
State University of New York Upstate Medical University Recruiting
Syracuse, New York, United States, 13210
Contact: Teresa C. Gentile    315-464-5476      
Principal Investigator: Teresa C. Gentile         
United States, North Carolina
Mission Hospital-Memorial Campus Withdrawn
Asheville, North Carolina, United States, 28801
Southeastern Medical Oncology Center-Clinton Recruiting
Clinton, North Carolina, United States, 28328
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Southeastern Medical Oncology Center-Goldsboro Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Wayne Memorial Hospital Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Southeastern Medical Oncology Center-Jacksonville Recruiting
Jacksonville, North Carolina, United States, 28546
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Rex Cancer Center Withdrawn
Raleigh, North Carolina, United States, 27607
Rex Cancer Center of Wakefield Withdrawn
Raleigh, North Carolina, United States, 27614
Iredell Memorial Hospital Recruiting
Statesville, North Carolina, United States, 28677
Contact: Ruby A. Grimm    704-873-5661      
Principal Investigator: Ruby A. Grimm         
Southeastern Medical Oncology Center-Wilson Recruiting
Wilson, North Carolina, United States, 27893
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Wake Forest University Health Sciences Recruiting
Winston-Salem, North Carolina, United States, 27157
Contact: Bayard L. Powell    336-713-6771      
Principal Investigator: Bayard L. Powell         
United States, North Dakota
Mid Dakota Clinic Terminated
Bismarck, North Dakota, United States, 58501
Saint Alexius Medical Center Terminated
Bismarck, North Dakota, United States, 58501
Sanford Bismarck Medical Center Withdrawn
Bismarck, North Dakota, United States, 58501
United States, Ohio
Toledo Clinic Cancer Centers-Bowling Green Withdrawn
Bowling Green, Ohio, United States, 43402
Aultman Health Foundation Recruiting
Canton, Ohio, United States, 44710
Contact: Kisa E. Weeman    330-363-6891      
Principal Investigator: Kisa E. Weeman         
Mercy Medical Center Recruiting
Canton, Ohio, United States, 44708
Contact: Mitchell Haut    888-293-4673      
Principal Investigator: Mitchell Haut         
Good Samaritan Hospital - Cincinnati Recruiting
Cincinnati, Ohio, United States, 45220
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
TriHealth Cancer Institute-Anderson Recruiting
Cincinnati, Ohio, United States, 45255
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
TriHealth Cancer Institute-Westside Recruiting
Cincinnati, Ohio, United States, 45247
Contact: Mehmet S. Copur    800-998-2119      
Principal Investigator: Mehmet S. Copur         
Case Western Reserve University Withdrawn
Cleveland, Ohio, United States, 44106
MetroHealth Medical Center Withdrawn
Cleveland, Ohio, United States, 44109
North Coast Cancer Care-Clyde Terminated
Clyde, Ohio, United States, 43410
Dayton CCOP Terminated
Dayton, Ohio, United States, 45420
Good Samaritan Hospital - Dayton Active, not recruiting
Dayton, Ohio, United States, 45406
Grandview Hospital Active, not recruiting
Dayton, Ohio, United States, 45405
Miami Valley Hospital Active, not recruiting
Dayton, Ohio, United States, 45409
Samaritan North Health Center Active, not recruiting
Dayton, Ohio, United States, 45415
Hematology Oncology Center Incorporated Active, not recruiting
Elyria, Ohio, United States, 44035
Mercy Cancer Center-Elyria Active, not recruiting
Elyria, Ohio, United States, 44035
Blanchard Valley Hospital Active, not recruiting
Findlay, Ohio, United States, 45840
Atrium Medical Center-Middletown Regional Hospital Active, not recruiting
Franklin, Ohio, United States, 45005-1066
Wayne Hospital Active, not recruiting
Greenville, Ohio, United States, 45331
Kettering Medical Center Active, not recruiting
Kettering, Ohio, United States, 45429
Lima Memorial Hospital Withdrawn
Lima, Ohio, United States, 45804
Saint Rita's Medical Center Recruiting
Lima, Ohio, United States, 45801
Contact: Henry Gerad    419-226-9617      
Principal Investigator: Henry Gerad         
Saint Luke's Hospital Terminated
Maumee, Ohio, United States, 43537
Toledo Clinic Cancer Centers-Maumee Withdrawn
Maumee, Ohio, United States, 43537
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center Withdrawn
Maumee, Ohio, United States, 43537
Fisher-Titus Medical Center Terminated
Norwalk, Ohio, United States, 44857
Saint Charles Hospital Withdrawn
Oregon, Ohio, United States, 43616
Toledo Clinic Cancer Centers-Oregon Withdrawn
Oregon, Ohio, United States, 43616
North Coast Cancer Care Active, not recruiting
Sandusky, Ohio, United States, 44870
Flower Hospital Recruiting
Sylvania, Ohio, United States, 43560
Contact: Jeffrey H. Muler    419-824-1842      
Principal Investigator: Jeffrey H. Muler         
Mercy Hospital of Tiffin Withdrawn
Tiffin, Ohio, United States, 44883
University of Toledo Withdrawn
Toledo, Ohio, United States, 43614
Mercy Saint Anne Hospital Withdrawn
Toledo, Ohio, United States, 43623
Saint Vincent Mercy Medical Center Withdrawn
Toledo, Ohio, United States, 43608
The Toledo Hospital/Toledo Children's Hospital Withdrawn
Toledo, Ohio, United States, 43606
Toledo Community Hospital Oncology Program CCOP Withdrawn
Toledo, Ohio, United States, 43617
Toledo Clinic Cancer Centers-Toledo Withdrawn
Toledo, Ohio, United States, 43623
Upper Valley Medical Center Active, not recruiting
Troy, Ohio, United States, 45373
Fulton County Health Center Withdrawn
Wauseon, Ohio, United States, 43567
Clinton Memorial Hospital Terminated
Wilmington, Ohio, United States, 45177
Greene Memorial Hospital Terminated
Xenia, Ohio, United States, 45385
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: Mohamad Cherry    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: Mohamad Cherry         
United States, Oregon
Bay Area Hospital Recruiting
Coos Bay, Oregon, United States, 97420
Contact: Bret A. Cook    541-269-8392    cherie.cox@bayareahospital.org   
Principal Investigator: Bret A. Cook         
United States, Pennsylvania
Abington Memorial Hospital Recruiting
Abington, Pennsylvania, United States, 19001
Contact: Willard G. Andrews    215-481-2402      
Principal Investigator: Willard G. Andrews         
Bryn Mawr Hospital Withdrawn
Bryn Mawr, Pennsylvania, United States, 19010
Butler Memorial Hospital Terminated
Butler, Pennsylvania, United States, 16001
Carlisle Regional Cancer Center Recruiting
Carlisle, Pennsylvania, United States, 17015
Contact: David F. Claxton    717-531-3779    CTO@hmc.psu.edu   
Principal Investigator: David F. Claxton         
Geisinger Medical Center Recruiting
Danville, Pennsylvania, United States, 17822
Contact: Joseph J. Vadakara    570-271-5251      
Principal Investigator: Joseph J. Vadakara         
Ephrata Community Hospital Withdrawn
Ephrata, Pennsylvania, United States, 17522
Ephrata Cancer Center Withdrawn
Ephrata, Pennsylvania, United States, 17522
Adams Cancer Center Withdrawn
Gettysburg, Pennsylvania, United States, 17325
Cherry Tree Cancer Center Withdrawn
Hanover, Pennsylvania, United States, 17331
Geisinger Medical Center-Cancer Center Hazleton Recruiting
Hazleton, Pennsylvania, United States, 18201
Contact: Joseph J. Vadakara    570-271-5251      
Principal Investigator: Joseph J. Vadakara         
Penn State Milton S Hershey Medical Center Recruiting
Hershey, Pennsylvania, United States, 17033-0850
Contact: David F. Claxton    717-531-3779    CTO@hmc.psu.edu   
Principal Investigator: David F. Claxton         
Lewistown Hospital Active, not recruiting
Lewistown, Pennsylvania, United States, 17044
Riddle Memorial Hospital Withdrawn
Media, Pennsylvania, United States, 19063
Paoli Memorial Hospital Withdrawn
Paoli, Pennsylvania, United States, 19301
Pennsylvania Hospital Withdrawn
Philadelphia, Pennsylvania, United States, 19107
University of Pennsylvania/Abramson Cancer Center Recruiting
Philadelphia, Pennsylvania, United States, 19104
Contact: Selina M. Luger    800-474-9892      
Principal Investigator: Selina M. Luger         
Phoenixville Hospital Recruiting
Phoenixville, Pennsylvania, United States, 19460
Contact: Carl W. Sharer    610-983-1908      
Principal Investigator: Carl W. Sharer         
Pottstown Memorial Medical Center Recruiting
Pottstown, Pennsylvania, United States, 19464
Contact: Wei (. Song    610-327-7544      
Principal Investigator: Wei (. Song         
Penn State Health Saint Joseph Medical Center Recruiting
Reading, Pennsylvania, United States, 19605
Contact: Marc A. Rovito    610-378-2336    danielward2@catholichealth.net   
Principal Investigator: Marc A. Rovito         
Guthrie Medical Group PC-Robert Packer Hospital Recruiting
Sayre, Pennsylvania, United States, 18840
Contact: Bradley W. Lash    800-836-0388      
Principal Investigator: Bradley W. Lash         
Geisinger Medical Group Active, not recruiting
State College, Pennsylvania, United States, 16801
Mount Nittany Medical Center Recruiting
State College, Pennsylvania, United States, 16803
Contact: David F. Claxton    717-531-3779    CTO@hmc.psu.edu   
Principal Investigator: David F. Claxton         
Chester County Hospital Recruiting
West Chester, Pennsylvania, United States, 19380
Contact: William E. Luginbuhl    610-431-5297      
Principal Investigator: William E. Luginbuhl         
Reading Hospital Recruiting
West Reading, Pennsylvania, United States, 19611
Contact: Terrence P. Cescon    610-988-9323      
Principal Investigator: Terrence P. Cescon         
Geisinger Wyoming Valley/Henry Cancer Center Recruiting
Wilkes-Barre, Pennsylvania, United States, 18711
Contact: Joseph J. Vadakara    570-271-5251      
Principal Investigator: Joseph J. Vadakara         
Susquehanna Cancer Center Recruiting
Williamsport, Pennsylvania, United States, 17701
Contact: Warren L. Robinson    800-598-4282      
Principal Investigator: Warren L. Robinson         
Lankenau Medical Center Withdrawn
Wynnewood, Pennsylvania, United States, 19096
Mainline Health CCOP Withdrawn
Wynnewood, Pennsylvania, United States, 19096
WellSpan Health-York Hospital Withdrawn
York, Pennsylvania, United States, 17405
United States, South Carolina
Greenville Health System Cancer Institute-Easley Recruiting
Easley, South Carolina, United States, 29640
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Memorial Hospital Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Butternut Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Eastside Recruiting
Greenville, South Carolina, United States, 29615
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Faris Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Saint Francis Hospital Recruiting
Greenville, South Carolina, United States, 29601
Contact: Robert D. Siegel    864-255-1713      
Principal Investigator: Robert D. Siegel         
Greenville Health System Cancer Institute-Andrews Active, not recruiting
Greenville, South Carolina, United States, 29605
Self Regional Healthcare Active, not recruiting
Greenwood, South Carolina, United States, 29646
Cancer Centers of the Carolinas-Greer Medical Oncology Withdrawn
Greer, South Carolina, United States, 29650
Greenville Health System Cancer Institute-Greer Recruiting
Greer, South Carolina, United States, 29650
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Seneca Recruiting
Seneca, South Carolina, United States, 29672
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville Health System Cancer Institute-Spartanburg Recruiting
Spartanburg, South Carolina, United States, 29307
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
United States, South Dakota
Rapid City Regional Hospital Recruiting
Rapid City, South Dakota, United States, 57701
Contact: Joshua C. Lukenbill    605-716-3982    research@rcrh.org   
Principal Investigator: Joshua C. Lukenbill         
Avera Cancer Institute Recruiting
Sioux Falls, South Dakota, United States, 57105
Contact: Addison R. Tolentino    800-657-4377    Jan.Healy@avera.org   
Principal Investigator: Addison R. Tolentino         
Avera McKennan Hospital and University Health Center Terminated
Sioux Falls, South Dakota, United States, 57105
United States, Tennessee
Thompson Cancer Survival Center Recruiting
Knoxville, Tennessee, United States, 37916
Contact: Samuel S. McCachren    865-541-1812      
Principal Investigator: Samuel S. McCachren         
United States, Texas
The Don and Sybil Harrington Cancer Center Active, not recruiting
Amarillo, Texas, United States, 79106
United States, Virginia
University of Virginia Cancer Center Withdrawn
Charlottesville, Virginia, United States, 22908
Danville Regional Medical Center Recruiting
Danville, Virginia, United States, 24541
Contact: Qiwei W. Gai    434-793-0044      
Principal Investigator: Qiwei W. Gai         
Fredericksburg Oncology Inc Withdrawn
Fredericksburg, Virginia, United States, 22401
Memorial Hospital Of Martinsville Recruiting
Martinsville, Virginia, United States, 24115
Contact: Sreedhar Katragadda    276-666-7827      
Principal Investigator: Sreedhar Katragadda         
United States, Washington
PeaceHealth Saint Joseph Medical Center Active, not recruiting
Bellingham, Washington, United States, 98225
Harrison HealthPartners Hematology and Oncology-Bremerton Active, not recruiting
Bremerton, Washington, United States, 98310
Kadlec Clinic Hematology and Oncology Active, not recruiting
Kennewick, Washington, United States, 99336
EvergreenHealth Medical Center Active, not recruiting
Kirkland, Washington, United States, 98033
Skagit Valley Hospital Active, not recruiting
Mount Vernon, Washington, United States, 98274
Harrison HealthPartners Hematology and Oncology-Poulsbo Active, not recruiting
Poulsbo, Washington, United States, 98370
Swedish Medical Center-First Hill Active, not recruiting
Seattle, Washington, United States, 98122-4307
Minor and James Medical PLLC Terminated
Seattle, Washington, United States, 98104
Pacific Medical Center-First Hill Active, not recruiting
Seattle, Washington, United States, 98104
Group Health Cooperative-Seattle Active, not recruiting
Seattle, Washington, United States, 98112
University of Washington Medical Center Active, not recruiting
Seattle, Washington, United States, 98195
Virginia Mason CCOP Active, not recruiting
Seattle, Washington, United States, 98101
Virginia Mason Medical Center Active, not recruiting
Seattle, Washington, United States, 98101
Cancer Care Northwest - Spokane South Active, not recruiting
Spokane, Washington, United States, 99202
Evergreen Hematology and Oncology PS Terminated
Spokane, Washington, United States, 99218
Wenatchee Valley Hospital and Clinics Active, not recruiting
Wenatchee, Washington, United States, 98801
United States, West Virginia
West Virginia University Charleston Recruiting
Charleston, West Virginia, United States, 25304
Contact: Steven J. Jubelirer    304-344-3457      
Principal Investigator: Steven J. Jubelirer         
West Virginia University Healthcare Recruiting
Morgantown, West Virginia, United States, 26506
Contact: Michael D. Craig    304-293-2745    sfilburn@hsc.wvu.edu   
Principal Investigator: Michael D. Craig         
Camden-Clark Memorial Hospital Active, not recruiting
Parkersburg, West Virginia, United States, 26101
Princeton Community Hospital Recruiting
Princeton, West Virginia, United States, 24740
Contact: Rowena Gonzales-Chambers    304-487-7000      
Principal Investigator: Rowena Gonzales-Chambers         
United States, Wisconsin
Fox Valley Hematology and Oncology Recruiting
Appleton, Wisconsin, United States, 54911
Contact: Timothy F. Goggins    920-749-1171      
Principal Investigator: Timothy F. Goggins         
Aurora Cancer Care-Burlington Recruiting
Burlington, Wisconsin, United States, 53105
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Marshfield Clinic-Chippewa Center Active, not recruiting
Chippewa Falls, Wisconsin, United States, 54729
Marshfield Clinic Cancer Center at Sacred Heart Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Aurora Cancer Care-Southern Lakes Recruiting
Elkhorn, Wisconsin, United States, 53121
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora Cancer Care-Grafton Recruiting
Grafton, Wisconsin, United States, 53024
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Green Bay Oncology at Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301-3526
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Green Bay Oncology Limited at Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Aurora BayCare Medical Center Recruiting
Green Bay, Wisconsin, United States, 54311-6519
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Mercy Health System Recruiting
Janesville, Wisconsin, United States, 53547
Contact: Emily G. Robinson    800-928-1103      
Principal Investigator: Emily G. Robinson         
UW Cancer Center Johnson Creek Active, not recruiting
Johnson Creek, Wisconsin, United States, 53038
Aurora Cancer Care-Kenosha South Recruiting
Kenosha, Wisconsin, United States, 53142
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Gundersen Lutheran Medical Center Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Kurt Oettel    608-775-2385    cancerctr@gundluth.org   
Principal Investigator: Kurt Oettel         
Dean Hematology and Oncology Clinic Recruiting
Madison, Wisconsin, United States, 53717
Contact: Amit Sanyal    608-410-2700      
Principal Investigator: Amit Sanyal         
University of Wisconsin Hospital and Clinics Active, not recruiting
Madison, Wisconsin, United States, 53792
Holy Family Memorial Hospital Active, not recruiting
Manitowoc, Wisconsin, United States, 54221
Vince Lombardi Cancer Clinic-Marinette Recruiting
Marinette, Wisconsin, United States, 54143
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Bay Area Medical Center Recruiting
Marinette, Wisconsin, United States, 54143
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Marshfield Clinic Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Saint Joseph's Hospital Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Aurora Advanced Healthcare Inc-Menomonee Falls Recruiting
Menomonee Falls, Wisconsin, United States, 53051
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora Cancer Care-Milwaukee Recruiting
Milwaukee, Wisconsin, United States, 53209
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora Saint Luke's Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53215
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora Sinai Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53233
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Froedtert and the Medical College of Wisconsin Recruiting
Milwaukee, Wisconsin, United States, 53226
Contact: Ehab L. Atallah    414-805-4380      
Principal Investigator: Ehab L. Atallah         
Marshfield Clinic-Minocqua Center Recruiting
Minocqua, Wisconsin, United States, 54548
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
D N Greenwald Center Active, not recruiting
Mukwonago, Wisconsin, United States, 53149
Oconomowoc Memorial Hospital-ProHealth Care Inc Recruiting
Oconomowoc, Wisconsin, United States, 53066
Contact: Timothy R. Wassenaar    262-928-5539    Chanda.miller@phci.org   
Principal Investigator: Timothy R. Wassenaar         
Green Bay Oncology - Oconto Falls Recruiting
Oconto Falls, Wisconsin, United States, 54154
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Vince Lombardi Cancer Clinic - Oshkosh Recruiting
Oshkosh, Wisconsin, United States, 54904
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora Cancer Care-Racine Recruiting
Racine, Wisconsin, United States, 53406-5661
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Marshfield Clinic at James Beck Cancer Center Recruiting
Rhinelander, Wisconsin, United States, 54501
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Marshfield Clinic-Rice Lake Center Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Vince Lombardi Cancer Clinic-Sheboygan Recruiting
Sheboygan, Wisconsin, United States, 53081
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Saint Nicholas Hospital Active, not recruiting
Sheboygan, Wisconsin, United States, 53081
Marshfield Clinic Cancer Care at Saint Michael's Hospital Recruiting
Stevens Point, Wisconsin, United States, 54481
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Saint Michael's Hospital Active, not recruiting
Stevens Point, Wisconsin, United States, 54481
Door County Cancer Center Active, not recruiting
Sturgeon Bay, Wisconsin, United States, 54235-1495
Green Bay Oncology - Sturgeon Bay Recruiting
Sturgeon Bay, Wisconsin, United States, 54235
Contact: Brian L. Burnette    800-432-6049      
Principal Investigator: Brian L. Burnette         
Aurora Medical Center in Summit Recruiting
Summit, Wisconsin, United States, 53066
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Vince Lombardi Cancer Clinic Recruiting
Two Rivers, Wisconsin, United States, 54241
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Waukesha Memorial Hospital Recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Timothy R. Wassenaar    262-928-5539    Chanda.miller@phci.org   
Principal Investigator: Timothy R. Wassenaar         
Aurora Cancer Care-Waukesha Recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aspirus Regional Cancer Center Recruiting
Wausau, Wisconsin, United States, 54401
Contact: Hamied R. Rezazadeh    877-405-6866      
Principal Investigator: Hamied R. Rezazadeh         
Aurora Cancer Care-Milwaukee West Recruiting
Wauwatosa, Wisconsin, United States, 53226
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Aurora West Allis Medical Center Recruiting
West Allis, Wisconsin, United States, 53227
Contact: Dhimant R. Patel    800-252-2990      
Principal Investigator: Dhimant R. Patel         
Marshfield Clinic - Weston Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Marshfield Clinic - Wisconsin Rapids Center Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Bilal H. Naqvi    800-839-3956      
Principal Investigator: Bilal H. Naqvi         
Riverview Hospital Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Ronnie J. Kirschling    877-405-6866      
Principal Investigator: Ronnie J. Kirschling         
United States, Wyoming
Rocky Mountain Oncology Terminated
Casper, Wyoming, United States, 82609
Welch Cancer Center Active, not recruiting
Sheridan, Wyoming, United States, 82801
Sponsors and Collaborators
Investigators
Principal Investigator: Alan List ECOG-ACRIN Cancer Research Group
  More Information

No publications provided

Responsible Party: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT00843882     History of Changes
Other Study ID Numbers: NCI-2009-01173, NCI-2009-01173, CDR0000634119, ECOG-E2905, E2905, E2905, U10CA180820, U10CA021115
Study First Received: February 12, 2009
Last Updated: August 28, 2015
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Anemia
Leukemia, Myelomonocytic, Acute
Leukemia, Myelomonocytic, Chronic
Myelodysplastic Syndromes
Preleukemia
Syndrome
Bone Marrow Diseases
Disease
Hematologic Diseases
Leukemia
Leukemia, Myeloid
Myelodysplastic-Myeloproliferative Diseases
Neoplasms
Neoplasms by Histologic Type
Pathologic Processes
Precancerous Conditions
Epoetin alfa
Lenalidomide
Thalidomide
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Anti-Bacterial Agents
Anti-Infective Agents
Antineoplastic Agents
Growth Inhibitors
Growth Substances
Hematinics
Hematologic Agents
Immunologic Factors
Immunosuppressive Agents

ClinicalTrials.gov processed this record on August 30, 2015