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Reproducibility of Magnetic Resonance Myocardial Salvage Index

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00794300
First Posted: November 20, 2008
Last Update Posted: November 20, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Leipzig
  Purpose
The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.

Condition Intervention
Myocardial Infarction Device: second magnetic resonance imaging scan

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Reproducibility of Myocardial Salvage Index in Acute Myocardial Infarction by Cardiac Magnetic Resonance Imaging

Resource links provided by NLM:


Further study details as provided by University of Leipzig:

Primary Outcome Measures:
  • Myocardial salvage index reproducibility [ Time Frame: 2 days ]

Secondary Outcome Measures:
  • infarct size reproducibility [ Time Frame: 2 days ]
  • area at risk reproducibility [ Time Frame: 2 days ]
  • microvascular obstruction reproducibility [ Time Frame: 2 days ]

Groups/Cohorts Assigned Interventions
Acute myocardial infarction patients Device: second magnetic resonance imaging scan

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ST-elevation myocardial infarction
Criteria

Inclusion Criteria:

  • ST-elevation myocardial infarction
  • Primary percutaneous coronary intervention

Exclusion Criteria:

  • Contraindications for magnetic resonance imaging
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00794300


Locations
Germany
University of Leipzig - Heart Center
Leipzig, Germany, 04289
Sponsors and Collaborators
University of Leipzig
Investigators
Principal Investigator: Holger Thiele, MD Heartcenter Leipzig GmbH
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00794300     History of Changes
Other Study ID Numbers: Repro100
First Submitted: November 19, 2008
First Posted: November 20, 2008
Last Update Posted: November 20, 2008
Last Verified: November 2008

Keywords provided by University of Leipzig:
reproducibility
contrast agent
magnetic resonance imaging
infarct size
myocardial salvage index
myocardial salvage assessment

Additional relevant MeSH terms:
Infarction
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases