Statins and Risk of Myocardial Infarction in Real Life in France - Full Text View

Purpose

The main objective of this case-referent study is to assess the impact of statins usage on the risk of having a first myocardial infarction (MI) in a real life situation in France

Condition
Myocardial Infarction


Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Prospective
Official Title:	Statins and Risk of Myocardial Infarction in Real Life in France

Resource links provided by NLM:

MedlinePlus related topics: Heart Attack Statins

U.S. FDA Resources

Further study details as provided by AstraZeneca:

Primary Outcome Measures:

Assess the impact of the different statins (molecules) usage on the risk of having a first myocardial infarction in a real life situation in France [ Time Frame: in 2011 ]

Secondary Outcome Measures:

Assess the interaction between statin treatment and risk factors such as cholesterol, age, gender, tobacco, alcohol, co-prescriptions, co-morbidities [ Time Frame: in 2011 ]
Assess the populational impact of statins usage on the risk of having a first myocardial infarction [ Time Frame: in 2011 ]
Assess the risk of having a first myocardial infarction according to high and low dosages of statins [ Time Frame: in 2011 ]


Enrollment:	13171
Study Start Date:	March 2007
Study Completion Date:	November 2010
Primary Completion Date:	November 2010 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Cases : Patients with a first myocardial infarction
2 Referents : Patients recruited by a GP during a routine consultation

Eligibility


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

Cases : Patients recruited by a cardiologist in hospital / Referents : Patients recruited by a GP, community sample

Criteria

Inclusion Criteria:

Patients can speak French or English
Patients can be interviewed by telephone
Place of usual residence in the area of recruitment

Exclusion Criteria:

Patients refusing to participate in the study
Patients who cannot be reached by telephone
Previous history of myocardial infarction

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00679575

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Locations


France
Research Site
Ambilly, France
Research Site
Angers, France
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Arles, France
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Bagnols sur Ceze, France
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Bayonne, France
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Beziers, France
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Boulogne sur mer, France
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Bourgoin Jallieu, France
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Bron, France
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Cambo les Bains, France
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Cenon, France
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Chateauroux, France
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Clermont Ferrand, France
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Colmar, France
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Crest, France
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Dijon, France
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Draguignan, France
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Eaubonne, France
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Firminy, France
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Forbach, France
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Frejus, France
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Gleize, France
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Grasse, France
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Gueret, France
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La Rochelle, France
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Langres, France
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Laon, France
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Le Coudray, France
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Le Mans, France
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Le Puy en Velay, France
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Mayenne, France
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Millau, France
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Montelimar, France
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Montfermeil, France
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Montpellier, France
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Nimes, France
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Orange, France
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Orleans, France
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Paris, France
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Pau, France
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Perpignan, France
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Puilboreau, France
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Rueil Malmaison, France
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Rumilly, France
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Saint Jean des Verges, France
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Sallanches, France
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Salon de provence, France
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Sens, France
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St Amand Monrond, France
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St-Esteve, France
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Thonon les Bains, France
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Toulouse, France
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Tours, France
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Tulles, France
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Valence, France
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Villefranche de Rouergue, France

Sponsors and Collaborators

AstraZeneca

Investigators


Study Chair:	Lucien Abenhaim	LA-SER29, rue du Faubourg Saint-Jacques75014 Paris

More Information


Responsible Party:	Russel Esterline, AstraZeneca
ClinicalTrials.gov Identifier:	NCT00679575 History of Changes
Other Study ID Numbers:	NIS-CFR-CRE-2007/1
Study First Received:	May 15, 2008
Last Updated:	December 6, 2010
Health Authority:	France: Haute Autorité de Santé Transparency Commission

Keywords provided by AstraZeneca:


statins myocardial infarction case-referent study France

Additional relevant MeSH terms:


Infarction Myocardial Infarction Ischemia Pathologic Processes Necrosis	Myocardial Ischemia Heart Diseases Cardiovascular Diseases Vascular Diseases

ClinicalTrials.gov processed this record on September 23, 2016