Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial (ATRSCC)

• ClinicalTrials.gov Identifier: NCT00619255
• Recruitment Status: Completed
• First Posted: February 20, 2008
• Results First Posted: November 7, 2017
• Last Update Posted: February 19, 2018
• Sponsor: University of Washington
• Collaborator: HRSA/Maternal and Child Health Bureau
• Information provided by (Responsible Party): Douglas Zatzick, University of Washington

Study Description

Brief Summary:

Recent needs assessments suggest that difficulties exist in care coordination between emergency medical services (EMS) systems and primary care for injured adolescents with alcohol problems and post-traumatic stress disorder (PTSD). This project will implement, evaluate, and disseminate the adolescent trauma support service model program that aims to enhance coordination between EMS systems and primary care/community services.

Condition or disease	Intervention/treatment	Phase
Post-traumatic Stress Disorder; Alcohol Abuse; Alcohol Dependence	Behavioral: Adolescent Trauma Support Program	Not Applicable

Detailed Description:

Goal 1: To coordinate care from EMS systems to primary care for injured adolescents.

Objective 1: To increase rates of connection to primary care providers to 55% for model program adolescents, compared to an anticipated connection rate of 25% in adolescents assigned to standard care, by 2010.

Goal 2: To reduce alcohol consumption over the course of the year after injury.

Objective 2: To reduce rates of alcohol consumption by 25% in adolescents assigned to the model program, compared to adolescents assigned to the standard care, by 2010.

Goal 3: To reduce adolescent PTSD symptoms over the course of the year after injury.

Objective 3: To achieve statistically significant reductions in PTSD symptoms in model program patients, compared to adolescents assigned to standard care, by 2010.

Activities Undertaken to Meet Project Goals:

We propose to implement and evaluate an innovative model program, the adolescent trauma support service, that aims to improve the quality of care for injured adolescents with problematic alcohol use and high levels of PTSD symptoms by enhancing coordination of care between EMS systems and primary care and community services. All injured adolescents ages 12-18 presenting to the Harborview Medical Center with injuries so severe that they require inpatient admission and/or 24 hour observation in the emergency department, will be screened for alcohol use and PTSD. Adolescents who screen into the study will be randomly assigned to the adolescent trauma support service or standard care. Two trauma support specialists will meet each injured adolescent and available family members by the ED gurney or inpatient bedside in order to elicit and address each patient/family's unique constellation of post-injury concerns. Next, the adolescent trauma support specialist will help to coordinate care received within the EMS system with primary care providers. The trauma support specialists will also have the capacity to deliver evidence-based motivational interviewing interventions targeting reductions in adolescent alcohol use. The trauma support specialists will link patients and families to evidence-based PTSD treatment through primary care and community resources. Program evaluation will include a comparison of the outcomes of adolescents randomly assigned to the adolescent trauma support program with those of adolescents assigned to standard care. Adolescents in the model program and standard care will be compared on the presence or absence of post-injury primary care visits and reductions in alcohol use and PTSD symptoms over the course of the year after injury. Nationwide dissemination activities of program evaluation results will include the publication of manuscripts in peer reviewed journals and presentations at national meetings by members of the interdisciplinary collaborative group that includes pediatric, mental health and surgical providers.

Study Design

• Study Type: Interventional (Clinical Trial)
• Actual Enrollment: 120 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Outcomes Assessor)
• Primary Purpose: Treatment
• Official Title: Maternal Child Health Bureau Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
• Actual Study Start Date: March 1, 2008
• Actual Primary Completion Date: October 31, 2010
• Actual Study Completion Date: June 1, 2014

Arms and Interventions

Arm	Intervention/treatment
Experimental: Intervention; Adolescent Trauma Support Program	Behavioral: Adolescent Trauma Support Program; The study team will be organized into an adolescent trauma support service. The adolescent trauma support service will fundamentally restructure psychosocial care by integrating post-injury medical treatment with alcohol and PTSD detection and treatment. The adolescent trauma support specialists will deliver a stepped collaborative care intervention to adolescents and their families over the 6-12 months post-injury.
No Intervention: Control; Usual Care Control Condition

Outcome Measures

Primary Outcome Measures :

1. Number of Patients With High Levels of Adolescent PTSD Symptoms [ Time Frame: Baseline (injury), then 2, 5, and 12 months post-injury ]
   Patients with symptoms consistent with a diagnosis of PTSD on the UCLA PTSD Reaction Index were counted. The UCLA PTSD-RI can be used to create an algorithm consistent with a diagnosis of PTSD by rating 1 intrusive, 3 avoidant, and 2 arousal symptoms with a rating of moderate severity. The PTSD-RI is scored on a scale from 0 (none of the time) - 4 (most of the time) with a > = 2 "some of the time" denoting this cutoff for moderate severity. This algorithm was used to identify patients with high PTSD symptom levels consistent with a diagnosis of PTSD.

Secondary Outcome Measures :

1. Number of Patients Who Self-reported Alcohol Consumption or Drug Use [ Time Frame: Baseline (injury), and 2, 5, and 12 months post-injury ]
   Any self-reported alcohol or drug use using one yes or no question
2. Percentage of Asolescents Linked to Primary Care During the Study [ Time Frame: Up to12 months post-injury ]
   Percentage of adolescents self-reporting one or more primary care visits over the course of the 12-months after the injury
3. Percentage of Adolescents Who Self-reported Weapon Carriage [ Time Frame: Baseline (injury), then 2, 5, and 12 months post-injury ]
   Self-reported carrying of knife, gun, club or other weapon by adolescent
4. Number of Patients Experiencing High-Level Depressive Symptoms [ Time Frame: Baseline (injury), then 2, 5, and 12 months post-injury ]
   The investigators used the Patient Health Questionnaire (PHQ-9) to identify symptoms consistent with a diagnosis of depression on the 9-item Patient Health Questionnaire depression screen. Scores range from 1 to 27 with higher scores representing worse outcomes.

Eligibility Criteria

• Ages Eligible for Study: 12 Years to 18 Years (Child, Adult)
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Criteria

Inclusion Criteria:

• The investigators will screen all English speaking female and male adolescents ages 12-18, who present to Harborview Medical Center with injuries so severe that they require inpatient admission and/or > 24 hour observation in the emergency department.
• All dyads where both parents consent and adolescents assent to the study will be enrolled in the study and randomized.

Exclusion Criteria:

• Adolescents who have suffered head, spinal cord, or other severe injuries that prevent participation in the baseline interview will be excluded from the protocol.
• Patients who require immediate intervention (e.g., self-inflicted injury, active psychosis, mania, and victims of family abuse) will be excluded and referred to the Harborview Inpatient Psychiatric Consult Service.
• Patients who are currently incarcerated or are likely to face criminal charges will be excluded.

Contacts and Locations

Locations

United States, Washington

Harborview Medical Center

Seattle, Washington, United States, 98104

Sponsors and Collaborators

University of Washington

HRSA/Maternal and Child Health Bureau

Investigators

• Principal Investigator: Douglas F. Zatzick, MD; University of Washington

More Information

Additional Information:

Our study is no longer recruiting, if you are seeking care for PTSD from Harborview Medical Center please follow this link. 

Publications of Results:

Zatzick D, Russo J, Lord SP, Varley C, Wang J, Berliner L, Jurkovich G, Whiteside LK, O'Connor S, Rivara FP. Collaborative care intervention targeting violence risk behaviors, substance use, and posttraumatic stress and depressive symptoms in injured adolescents: a randomized clinical trial. JAMA Pediatr. 2014 Jun;168(6):532-9. doi: 10.1001/jamapediatrics.2013.4784.

• Responsible Party: Douglas Zatzick, Professor, University of Washington
• ClinicalTrials.gov Identifier: NCT00619255
• Other Study ID Numbers: 32685; 1 H34 MC08508-01-00; 07-7850-C01 ( Other Identifier: University of Washington )
• First Posted: February 20, 2008
• Results First Posted: November 7, 2017
• Last Update Posted: February 19, 2018
• Last Verified: February 2018

Keywords provided by Douglas Zatzick, University of Washington:

Adolescents; Quality Assurance and Improvement; Substance Abuse; Posttraumatic Stress; Family Centered Care; Trauma Systems

Additional relevant MeSH terms:

Alcoholism; Stress Disorders, Traumatic; Stress Disorders, Post-Traumatic; Trauma and Stressor Related Disorders; Mental Disorders; Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders