Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1) (COGENT-1)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00557921
Recruitment Status : Terminated (Terminated by Sponsor)
First Posted : November 14, 2007
Last Update Posted : January 28, 2009
Information provided by:
Cogentus Pharmaceuticals

Brief Summary:

The purpose of the COGENT-1 clinical trial is to determine whether CGT-2168 (clopidogrel and omeprazole) compared to clopidogrel is safe and effective in reducing the incidence of gastrointestinal bleeding and symptomatic ulcer disease, in the setting of concomitant aspirin therapy.

Antiplatelet therapy is an essential element of care for patients with atherothrombotic disease. Bleeding is a fundamental adverse effect of all antiplatelet drugs including aspirin, clopidogrel and dual antiplatelet regimens.

The gastrointestinal tract is the most common site of bleeding related to antiplatelet therapy, typically in connection with peptic ulcer disease. Recently published studies suggest the use of clopidogrel carries a gastrointestinal bleeding risk similar to that of aspirin or non-aspirin non-steroidal anti-inflammatory drugs. Patients taking any two of these drugs (clopidogrel, aspirin and/or non-aspirin NSAIDs) are exposed to an even higher risk of bleeding and ulcer disease.

Cogentus Pharmaceuticals is launching phase 3 trials of a novel combination product, CGT-2168, which has the potential to significantly reduce this problem and increase patient safety. CGT-2168 combines a standard dosage of clopidogrel and a gastroprotectant (omeprazole) in a once-daily pill that may reduce the likelihood of adverse gastrointestinal events.

Condition or disease Intervention/treatment Phase
Acute Coronary Syndrome Myocardial Infarction Coronary Artery Disease Percutaneous Coronary Intervention Drug: CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin Drug: Plavix (clopidogrel 75 mg) and aspirin Phase 3

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 5000 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease
Study Start Date : December 2007
Estimated Primary Completion Date : November 2009
Estimated Study Completion Date : November 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: 1 Drug: CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin
(CGT-2168 active and Comparator placebo, one capsule each daily; and enteric coated aspirin at daily dose level assigned by study physician)
Active Comparator: 2 Drug: Plavix (clopidogrel 75 mg) and aspirin
(CGT-2168 placebo and Comparator active, one capsule each daily; and enteric coated aspirin at daily dose level assigned by study physician)

Primary Outcome Measures :
  1. Composite of upper gastrointestinal clinical events, including gastroduodenal bleeding, symptomatic gastroduodenal ulcer, persistent pain with multiple gastric erosions, obstruction or perforation [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]

Secondary Outcome Measures :
  1. Composite of gastroduodenal bleeding, symptomatic gastroduodenal ulcer, obstruction or perforation [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]
  2. Composite of gastroduodenal bleeding, obstruction or perforation [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]
  3. Discontinuation of study medication attributed to gastrointestinal signs or symptoms [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]
  4. Gastroesophageal reflux disease, as evidenced by symptomatic endoscopically-confirmed erosive esophagitis [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]
  5. Dyspepsia, defined as an increase of at least ten points on the "pain intensity" component of the SODA instrument from baseline [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]
  6. Occurrence of a cardiovascular event (cardiovascular death, nonfatal myocardial infarction, CABG or PCI, or confirmed ischemic stroke [ Time Frame: Anticipated minimum of 48 weeks, up to end of study ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients in whom a requirement for clopidogrel therapy with concomitant aspirin is anticipated for at least the next 12 months. Specific conditions that may confer a need for long-term clopidogrel + aspirin therapy may include non-ST segment elevation acute coronary syndrome (unstable angina/non-Q-wave MI), ST segment elevation acute MI), or new placement of a coronary artery stent.
  • For women of childbearing potential, negative pregnancy test prior to randomization and agreement to use effective method of birth control during the study.
  • Able to provide written informed consent based on competent mental status.

Exclusion Criteria:

  • Patients currently hospitalized for whom discharge is not anticipated within 48 hours of randomization.
  • Requirement for current or chronic use of a proton pump inhibitor, H2 receptor blocker, sucralfate or misoprostol.
  • Erosive esophagitis, esophageal or gastric variceal disease, or non-endoscopic gastric surgery. Patients with a history of GERD/erosive esophagitis or dyspepsia who do not currently require proton pump blockers will be eligible.
  • Receipt of > 21 days of clopidogrel or another thienopyridine prior to randomization.
  • Oral anticoagulation that cannot be safely discontinued for duration of study.
  • Recent fibrinolytic therapy.
  • Scheduled percutaneous coronary intervention (PCI). Patients may be enrolled upon completion of PCI.
  • Recent (< 30 days prior to randomization) or scheduled coronary artery bypass graft (CABG) surgery.
  • Cardiogenic shock at time of randomization, refractory ventricular arrhythmias, or congestive heart failure (NY Heart Association class IV).
  • Active pathological bleeding or a history of hereditary or acquired hemostatic disorder.
  • History of hemorrhagic stroke, intracranial neoplasm, arteriovenous malformation or aneurysm.
  • Systemic corticosteroids except low-dose oral corticosteroids equivalent to prednisone < or equal to 5 mg/day.
  • Allergy or contraindication to clopidogrel or other thienopyridine drugs, omeprazole or other proton pump inhibitor drugs, aspirin or salicylate derivatives, or other study drug ingredients.
  • Treatment within 30 days prior to randomization with any investigational drug or device including investigational coronary artery stents or currently enrolled in another interventional drug or device study.
  • Women who are pregnant or breastfeeding.
  • Life expectancy less than 12 months.
  • Laboratory abnormality at screening that is clinically significant or outside protocol-allowed limits, or any other condition that precludes participation in the study in the opinion of the Investigator.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00557921

  Hide Study Locations
United States, Alabama
Alabama Clinical Research Institute, Inc. (ACRI)
Alexander City, Alabama, United States, 35010
Alabama Clinical Therapeutics, LLC
Birmingham, Alabama, United States, 35126
Cardio-Thoracic Surgeons P.C.
Birmingham, Alabama, United States, 35213
Birmingham Heart Clinic, PC
Birmingham, Alabama, United States, 35235
John F Simmons , MD PC
Geneva, Alabama, United States, 36340
Clinical Research Consultants, Inc.
Hoover, Alabama, United States, 35216
The Heart Center, PC
Huntsville, Alabama, United States, 35801
Mobile Heart Specialists, PC
Mobile, Alabama, United States, 36608
United States, Arizona
Advanced Cardiac Specialists
Mesa, Arizona, United States, 85206
Redpoint Research
Phoenix, Arizona, United States, 85029
Cardiovascular Consultants, Ltd.
Phoenix, Arizona, United States, 85032
Cochise Clinical Research
Sierra Vista, Arizona, United States, 85635
Paradigm Clinical Research, Inc.
Tucson, Arizona, United States, 85705
United States, Arkansas
Tri-Lakes Research
Hot Springs, Arkansas, United States, 71901
Michael A. Frais, Cardiologist, P.A.
Hot Springs, Arkansas, United States, 71913
NEA-Clinic Cardiology
Jonesboro, Arkansas, United States, 72401
Searcy Medical Center
Searcy, Arkansas, United States, 72143
United States, California
Cardiology Consultants of Orange County
Anaheim, California, United States, 92801
Chest and Critical Care Consultants, A Medical Group
Anaheim, California, United States, 92801
Clinical Solutions Advantage
Buena park, California, United States, 90620
Turns Institute for Clinical Research
Castro Valley, California, United States, 94546
Escondido Cardiology Associates
Escondido, California, United States, 92025
Accurate Clinical Trials, Inc.
Laguna Hills, California, United States, 92653
Therapeutic Research Institute of Orange County
Laguna Hills, California, United States, 92653
Kirtik Thaker MD
Lakewood, California, United States, 90712
Los Angeles Cardiology Associates
Los Angeles, California, United States, 90017
Merced Heart Associates
Merced, California, United States, 95348
Mission Internal Medical Group
Mission Viejo, California, United States, 92691
Altos Cardiovascular Associates
Mountain View, California, United States, 94040
Kenneth W. Carr, MD, Cardiology
Oceanside, California, United States, 92056
Rancho CucamongaClinical Trials
Rancho Cucamonga, California, United States, 91703
Inland Heart and Vascular Medical Associates
San Bernardino, California, United States, 92404
Ritchken and First
San Diego, California, United States, 92117
Rider Research Group
San Francisco, California, United States, 94117
Richard Levy, MD.
San Francisco, California, United States, 94118
Kaiser Permanente
San Jose, California, United States, 95119
Medical Helping Hands Research
Santa Ana, California, United States, 92704
Pacific Heart Institute
Santa Monica, California, United States, 90404
Radiant Research
Santa Rosa, California, United States, 95405
Harbor- UCLA Medical Center
Torrance, California, United States, 90509
Ventura Cardiology Consultants Medical Group, Inc.
Ventura, California, United States, 93003
United States, Colorado
Colorado Springs Health Partners
Colorado Springs, Colorado, United States, 80907
United States, Connecticut
Connecticut Clinical Research
Bridgeport, Connecticut, United States, 06606
Hartford Hospital
Hartford, Connecticut, United States, 06102
United States, Delaware
Alfieri Cardiology, PA
Newark, Delaware, United States, 19713
United States, District of Columbia
Washington V.A. Medical Center
Washington, District of Columbia, United States, 20422
United States, Florida
Oscar R. Guerra, MD PA
Coral Gables, Florida, United States, 33134
Deerfield Beach Cardiology Associates
Deerfield Beach, Florida, United States, 33442
Dr Jules Cohen
Hallandale, Florida, United States, 33009
Empire International Research
Hialeah, Florida, United States, 33012
Cardiovascular Consultants of South Florida
Hollywood, Florida, United States, 33021
Jacksonville Heart Center
Jacksonville, Florida, United States, 32207
Jacksonville Center for Clinical Research
Jacksonville, Florida, United States, 32216
Jacksonville Heart Center
Jacksonville, Florida, United States, 32250
CVMS Resesarch Institute, LLC
Jupiter, Florida, United States, 33458
Watson Clinic Center for Research
Lakeland, Florida, United States, 33805
Alpha Medical Research, LLC
Melbourne, Florida, United States, 32901
Empire International Research
Miami, Florida, United States, 33125
Suncoast Research Group, LLC
Miami, Florida, United States, 33144
Cardiovascular Research Center of South Florida
Miami, Florida, United States, 33173
Research Center Phase I-IV of Florida Corp.
Miami, Florida, United States, 33175
Empire International Research
Miami, Florida, United States, 33186
Bert Fish Medical Center
New Smyrna Beach, Florida, United States, 32168
Central Florida Cardiology Group
Orlando, Florida, United States, 32803
Cardiology Assocaites of Orlando d/b/a Orlando Heart Center
Orlando, Florida, United States, 32806
Sunset Point Medical Associates
Palm Harbor, Florida, United States, 34684
Berma Research Group
Plantation, Florida, United States, 33317
Charlotte Heart Group Research Center
Port Charlotte, Florida, United States, 33952
Suncoast Cardiovascular Research
St. Petersburg, Florida, United States, 33701
The Heart and Vascular Institute of Florida
St. Petersburg, Florida, United States, 33709
G&G Research Baker-Tombul Cardiology
Vero Beach, Florida, United States, 32960
Carlos Levy, D.O.
Weston, Florida, United States, 33326
United States, Georgia
Piedmont Hospital
Atlanta, Georgia, United States, 30309
Primary Care Specialists, LLC/ ECAST CT
Atlanta, Georgia, United States, 30312
Executive Health and Research Associates, Inc.
Atlanta, Georgia, United States, 30342
Southeast Regional Research Group
Columbus, Georgia, United States, 31904
Georgia Heart Specialists, LLC
Covington, Georgia, United States, 30014
Ialum Clinical Research Center, LLC
Decatur, Georgia, United States, 30032
Ialum Clinical Research Center
Decatur, Georgia, United States, 30032
Ialum Clinical Research Center
Decatur, Georgia, United States, 30035
Southeast Regional Research Group
Savannah, Georgia, United States, 31406
Medsouth Primary CareStockbridge
Stockbridge, Georgia, United States, 30281
United States, Illinois
South Suburban Health Professional Group, PC
Flossmoor, Illinois, United States, 60422
Consultants in Cardiovascular Medicine
Melrose Park, Illinois, United States, 60160
Methodist Medical Center of Illinois
Peoria, Illinois, United States, 61606
United States, Indiana
Community Clinical Research Center
Anderson, Indiana, United States, 46011
American Health Network
Avon, Indiana, United States, 46123
Indiana Medical Research
Elkhart, Indiana, United States, 46514
Welborn Clinic
Evansville, Indiana, United States, 47713
Indiana Heart Physicians
Indianapolis, Indiana, United States, 46237
United States, Iowa
Midwest Cardiovascular Research Foundation
Davenport, Iowa, United States, 52803
Northeast Iowa Medical Education Foundation
Waterloo, Iowa, United States, 50702
United States, Kansas
Hutchinson Clinic, P.A.
Hutchinson, Kansas, United States, 67502
Venture Resource Group, Inc.
Mission, Kansas, United States, 66202
Midwest Cardiology Assocaites
Overland Park, Kansas, United States, 66209
United States, Kentucky
Cumberland Cardiology
Ashland, Kentucky, United States, 41101
Trover Health System
Madisonville, Kentucky, United States, 42431
Owensboro Heart and Vascular
Owensboro, Kentucky, United States, 42303
United States, Louisiana
Dolby Research, LLC
Baton Rouge, Louisiana, United States, 33437
Cardiovascular Institute of the South
Houma, Louisiana, United States, 70301
Heart Clinic of Louisiana Clinical Research, LLC.
Marrero, Louisiana, United States, 70072
United States, Maine
Maine Research Associates
Auburn, Maine, United States, 04210
Cardiovascular Consultants of Maine, PA
Scarborough, Maine, United States, 04074
Maine Cardiology Associates
South Portland, Maine, United States, 04106
United States, Maryland
Good Samaritan Hospital (Medstar Health)
Baltimore, Maryland, United States, 21239
eCast Corporation
Greenbelt, Maryland, United States, 20770
Atlantic Cardiology Associates, P.A
Salisbury, Maryland, United States, 21801
Peninsula Cardiology Associates
Salisbury, Maryland, United States, 21804
United States, Massachusetts
Pentucket Medical Associates
Haverhill, Massachusetts, United States, 01830
Charles River Medical Associates
Natick, Massachusetts, United States, 01760
United States, Michigan
Michigan Cardiovascular Institute
Bay City, Michigan, United States, 48708
Apex Medical Research, AMR, Inc.
Flint, Michigan, United States, 48504
Borgess Research Institute
Kalamazoo, Michigan, United States, 49048
Michigan Cardiovascular Institute
Midland, Michigan, United States, 48670
Michigan Cardiovascular Institute
Saginaw, Michigan, United States, 48601
Covenant Medical Center, Inc.
Saginaw, Michigan, United States, 48602
Academic Heart and Vascular PLLC
St. Clair Shores, Michigan, United States, 48081
Oakland Medical Center
Troy, Michigan, United States, 48085
Waterford Medical Assoc. P.C.
Waterford, Michigan, United States, 48328
Michigan Heart, PC
Ypsilanti, Michigan, United States, 48106
United States, Minnesota
Duluth Clinic / Saint Marys Medical Center
Duluth, Minnesota, United States, 55805
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Regions Hospital
St. Paul, Minnesota, United States, 55101
United States, Mississippi
New Coast Cardiology Center, PLLC
Gulfport, Mississippi, United States, 39503
United States, Missouri
PPS Clinical Research, STL, LLC
Chesterfield, Missouri, United States, 63017
Kansas City VA Medical Center
Kansas City, Missouri, United States, 64128
Cardiology Diagnostics, Ltd.
St. Louis, Missouri, United States, 63122
United States, Montana
Glacier View Cardiology
Kalispell, Montana, United States, 59901
Saint Patrick Hospital- International Heart Institute of Montana
Missoula, Montana, United States, 59802
United States, Nebraska
The Creighton Cardiac Center
Omaha, Nebraska, United States, 68131
Alegent Health Clinic Heart and Vascular Specialist
Papillion, Nebraska, United States, 68046
United States, Nevada
Nevada Cardiology Associates
Las Vegas, Nevada, United States, 89128
United States, New Hampshire
Lahey Cardiology @ the Medical Center
Nashua, New Hampshire, United States, 03060
United States, New Jersey
Associated Cardiovascular Consultants
Cherry Hill, New Jersey, United States, 08034
Cardiovascular Associates of the Delaware Valley, P.A.
Elmer, New Jersey, United States, 08318
Cardiovascular Associates of the Delaware Valley, P.A.
Haddon Heights, New Jersey, United States, 08035
Cardiovascular Associates of the Delaware Valley, P.A.
Sewell, New Jersey, United States, 08080
Physicans Research Center, LLC
Toms River, New Jersey, United States, 08755
United States, New York
Capital Cardiology Associates
Albany, New York, United States, 12211
Cardiac Care and Vascular Medicine, Albert Einstein College of Medicine
Bronx, New York, United States, 10469
Hudson Valley Cardiology Group, P.C.
Cortlandt Manor, New York, United States, 10567
Cardiology Associates, P.C.
Johnson City, New York, United States, 13790
Long Island Heart Associates
Mineola, New York, United States, 11501
Slocum-Dickson Medical Group, PLLC
New Hartford, New York, United States, 13413
Sound Shore Cardiology, P.C.
New Rochelle, New York, United States, 10801
New York Cardiovascular Associate
New York, New York, United States, 10001
St. Luke's- Roosevelt Hospital
New York, New York, United States, 10025
Rochester General Hospital
Rochester, New York, United States, 14621
Saratoga Cardiology Assoc, PC
Saratoga Springs, New York, United States, 12866
Westchester Cardiology Associates
Scarsdale, New York, United States, 10583
Good Samaritan Hospital
Suffern, New York, United States, 10901
Cardiology, PC
Syracuse, New York, United States, 13210
SUNY Upstate Medical University
Syracuse, New York, United States, 13210
Capital Cardiology Associates
Troy, New York, United States, 12180
Buffalo Cardiology and Pulmonary Associates
Williamsville, New York, United States, 14221
Mark J. Kozinn, MD
Williamsville, New York, United States, 14221
United States, North Carolina
Clinical Study Center of Asheville, LLC
Asheville, North Carolina, United States, 28803
Kernodle Clinic, Inc.
Burlington, North Carolina, United States, 27215
Metrolina Medical Research
Charlotte, North Carolina, United States, 28209
Diversified Research
Durham, North Carolina, United States, 27704
Cumberland Research Associates, LLC
Fayetteville, North Carolina, United States, 28304
Cardiovascular Care of Northern Carolina
Oxford, North Carolina, United States, 27565
United States, North Dakota
St. Alexius Medical Center
Bismarck, North Dakota, United States, 58501
Altru Health Systems
Grand Forks, North Dakota, United States, 58201
Trinity Health
Minot, North Dakota, United States, 58701
United States, Ohio
George G. Ellis, Jr. M.D., Inc.
Boardman, Ohio, United States, 44512
Cardiovascular Research Institute, LLC
Canton, Ohio, United States, 44710
Comprehensive Cardiology Consultants, Inc.
Cincinnati, Ohio, United States, 45236
Midwest Cardiology Research Foundation
Columbus, Ohio, United States, 43214
Prestige Clinical Research
Franklin, Ohio, United States, 45005
St. Vincent Mercy Medical Center
Toledo, Ohio, United States, 43608
Cardiology Associates of SE Ohio, Inc
Zanesville, Ohio, United States, 43701
Physicans Research, Inc.
Zanesville, Ohio, United States, 43701
United States, Oklahoma
Bluestem Cardiology Research Dept.
Bartlesville, Oklahoma, United States, 74006
Oklahoma Cardiovascular Research Group
Oklahoma City, Oklahoma, United States, 73109
Aquilo Research
Yukon, Oklahoma, United States, 73099
United States, Oregon
Bend Memorial Clinic
Bend, Oregon, United States, 97701
Hillsboro Cardiology, PC
Hillsboro, Oregon, United States, 97123
Legacy Clinical Research
Portland, Oregon, United States, 97210
United States, Pennsylvania
Abington Medical Specialists
Abington, Pennsylvania, United States, 19001
Tri-State Medical Group
Beaver, Pennsylvania, United States, 15009
Heritage Cardiology Association
Camp Hill, Pennsylvania, United States, 17011
Premier Heart Specialists
Easton, Pennsylvania, United States, 18042
Heart Specialists of Lancaster
Ephrata, Pennsylvania, United States, 17522
Penn State Hershey Medical Center
Hershey, Pennsylvania, United States, 17033
Pennsylvania Heart and Vascular Group, P.C.
Jenkintown, Pennsylvania, United States, 19046
Comprehensive Cardiology Consultants
Langhorne, Pennsylvania, United States, 19047
Sewickley Valley Medical Group Cardiology
Leetsdale, Pennsylvania, United States, 15056
Cardiology Consultants of Philadelphia
Norristown, Pennsylvania, United States, 19401
Hospital of the University of Pennsylvania Cardiology Department
Philadelphia, Pennsylvania, United States, 19104
Cardiology Consultants of Philadelphia
Philadelphia, Pennsylvania, United States, 19111
Albert Einstein Medical Center
Philadelphia, Pennsylvania, United States, 19141
Cardiology Consultants of Philadelphia
Philadelphia, Pennsylvania, United States, 19148
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, United States, 15240
Advanced Cardiology Specialists
Scranton, Pennsylvania, United States, 18501
Elite Medical Research, Inc.
Sellersville, Pennsylvania, United States, 18960
Cardiology Consultants of Philadelphia
Upland, Pennsylvania, United States, 19013
West Chester Cardiology, PC
West Chester, Pennsylvania, United States, 19380
Berks Cardiology, Ltd.
Wyomissing, Pennsylvania, United States, 19610
Cardiology Consultants of Philadelphia
Yardley, Pennsylvania, United States, 19067
United States, Rhode Island
New England Center for Clinical Research&comma; Inc
Cranston, Rhode Island, United States, 02920
Rhode Island Hospital Cardiology
Providence, Rhode Island, United States, 02903
Cardiology Specialists
Westerly, Rhode Island, United States, 02891
United States, South Carolina
Palmetto Clinical Research
Summerville, South Carolina, United States, 29485
United States, Tennessee
McMinn Medical Group (DBA: Athens Medical Group)
Athens, Tennessee, United States, 37303
Verzosa & Ungab Internal Medicine Associates
Bartlett, Tennessee, United States, 38134
Middle Tennessee Clinical Research
Fayetteville, Tennessee, United States, 37334
Research Associates of Jackson and Apex Cardiology
Jackson, Tennessee, United States, 38301
Tri-State Cardiology
Johnson City, Tennessee, United States, 37601
Memphis Internal Medicine
Memphis, Tennessee, United States, 38119
Goodlife Medical Center
Memphis, Tennessee, United States, 38120
Heart and Vascular Clinic
Nashville, Tennessee, United States, 37203
United States, Texas
Family Health Care Assoc.
Arlington, Texas, United States, 76013
Southeast Texas Clinical Research Center
Beaumont, Texas, United States, 77702
Trinity Hypertension and Diagnostic Res.
Carrollton, Texas, United States, 75006
VA Medical Center
Dallas, Texas, United States, 75216
U.T. Southwestern
Dallas, Texas, United States, 75390
Amir Malik Research
Fort Worth, Texas, United States, 76104
The University of Texas Medical Branch at Galveston
Galveston, Texas, United States, 77555-0553
East Texas Cardiology PA
Houston, Texas, United States, 77002
Office of Amer Zaheer, MD
Houston, Texas, United States, 77004
Office of Salim Gopalani, MD
Houston, Texas, United States, 77008
Comprehensive Heart Care, PA
Houston, Texas, United States, 77024
Century Clinical Research
Houston, Texas, United States, 77036
Office of Mizra Basith Baig, MD
Houston, Texas, United States, 77055
Covenant Cardiology Associates
Lubbock, Texas, United States, 79410
South Texas Institutes of Health
Mcallen, Texas, United States, 78572
Texas Regional Heart Center d/b/a Legacy Heart Center
Plano, Texas, United States, 75024
Heart & Vascular Institute of Texas
San Antonio, Texas, United States, 78217
Cardiology Clinic of San Antonio
San Antonio, Texas, United States, 78229
South Texas Cardiovascular Consultants
San Antonio, Texas, United States, 78229
IMED Research, PA
San Antonio, Texas, United States, 78258
Southwest Health Associate, PA
Sugar Land, Texas, United States, 77478
Office of Dwayne O. Williams, MD
Sugarland, Texas, United States, 77479
Kings Daughters Clinic
Temple, Texas, United States, 76502
Victoria Heart and Vascular Center
Victoria, Texas, United States, 77901
United States, Virginia
Cardiology Consultants of Danville
Danville, Virginia, United States, 24541
Triad Research Institute
Galax, Virginia, United States, 24333
Virginia Cardiovascular Specialists
Richmond, Virginia, United States, 23226
Winchester Medical Center/ Clinical Research Department
Winchester, Virginia, United States, 22601
United States, Washington
Daniel W. Gottlieb, MD, PS
Burien, Washington, United States, 98166
Heart Clinic Northwest
Spokane, Washington, United States, 99204
Inland Cardiology Assocaites
Spokane, Washington, United States, 99204
Franciscan Health System dba FHS Research Center
Tacoma, Washington, United States, 98405
United States, West Virginia
Parkersburg Cardiology Associates
Parkersburg, West Virginia, United States, 26101
United States, Wisconsin
Wisconsin Heart, S.C.
Madison, Wisconsin, United States, 53715
Heart Care Associates, LLC
Milwaukee, Wisconsin, United States, 53215
Australia, Australian Capital Territory
The Canberra Hospital
Garran, Australian Capital Territory, Australia, 2605
Australia, New South Wales
Coffs Harbour Cardiology
Coffs Harbour, New South Wales, Australia, 2450
Cardiac Research Institute
Eastwood, New South Wales, Australia, 2122
Australia, Queensland
Wesley research institute
Auchenflower, Queensland, Australia, 4066
Cairns Base Hospital
Cairns, Queensland, Australia, 4870
Royal Brisbane and Women's Hospital
Herston, Queensland, Australia, 4029
Australia, Tasmania
Royal Hobart Hospital
Hobart, Tasmania, Australia, 7001
Launceston General Hospital
Launceston, Tasmania, Australia, 7250
Australia, Victoria
Northern Hospital
Epping, Victoria, Australia, 3076
St.Vincent's Hospital (Melb)
Fitzroy, Victoria, Australia, 3065
Geelong Hospital- Barwon Health
Geelong, Victoria, Australia, 3220
Australia, Western Australia
Fremantle Hospital
Fremantle, Western Australia, Australia, 6160
Multiprofile Hospital for Active Treatment "Sveta Ekaterina", 1st Department of Internal Diseases
Dimitrovgrad, Bulgaria
Multiprofile Hospital for Active Treatment "Dr. Georgi Stranski, Clinic of Cardiology
Pleven, Bulgaria
Multiprofile Hospital for Active Treatment ''Sveti Georgi'', Cardiology Clinic
Plovdiv, Bulgaria
Multiprofile Hospital for Active Treatment ''Sveti Panteleymon'', 2nd Department. of Internal Diseases - Intensive Cardiology Unit
Plovdiv, Bulgaria
Multiprofile Hospital for Active Treatment - Ruse, 4th Department of Internal Diseases
Rousse, Bulgaria
4th Multiprofile Hospital for Active Treatment
Sofia, Bulgaria
Military Medical Academy, Clinic of Cardiology and Intensive Care
Sofia, Bulgaria
Multiprofile Hospital for Active Treatment and Emergency Medicine "Pirogov". Cardiology Clinic
Sofia, Bulgaria
National Heart Hospital Department of Cardiology
Sofia, Bulgaria
National Multiprofile Transport Hospital "Tsar Boris III, Cardiology Clinic
Sofia, Bulgaria
Tokuda Hospital Department of Cardiology
Sofia, Bulgaria
University Multiprofile Hospital for Active Treatment ''Tsaritsa Ioanna'' - ISUL, Cardiology Clinic
Sofia, Bulgaria
Multiprofile Hospital for Active Treatment "Sveta Marina", Clinic of Internal Diseases - 2nd Internal Department
Varna, Bulgaria
Canada, British Columbia
Dr. Tsui
Maple Ridge, British Columbia, Canada, V2X 5Z6
Fraser Clinical Trials Inc and Royal Columbian Hospital
New Westminster, British Columbia, Canada, V3L3W4
Vancouver General Hospital
Vancouver, British Columbia, Canada, V5Z 1M9
Victoria Heart Institute Foundation
Victoria, British Columbia, Canada, V8R4R2
Canada, Manitoba
Health Sciences Centre
Winnipeg, Manitoba, Canada, R3A1R9
Canada, New Brunswick
South East Regional Health Authority
Moncton, New Brunswick, Canada, E1C4B7
Canada, Newfoundland and Labrador
Commonwealth Medical Clinic
Mount Pearl, Newfoundland and Labrador, Canada, A1N1W7
Canada, Ontario
Cambridge Cardiac Care Centre
Cambridge, Ontario, Canada, NIR-6V6
Mississauga Clinical Research Center
Mississauga, Ontario, Canada, L5B2P7
Dr. George Zimakas
Niagara Falls, Ontario, Canada, L2G5X7
Dr. James Y. Cha
Oshawa, Ontario, Canada, L1J2K1
Curans Health Center
Thunder Bay, Ontario, Canada, P7R2Z3
Toronto East Cardiology Associates Inc.
Toronto, Ontario, Canada, M4C-1N2
Canada, Quebec
Recherches Cliniques Theradev
Granby, Quebec, Canada, J2G8Z9
ViaCar Recherche Clinique Inc.
Greenfield Park, Quebec, Canada, J4N1L6
ViaCar Recherche Clinique Inc
Longueuil, Quebec, Canada, J4N1L6
Hospitalier de l'Universite de Montreal Hotel Dieu
Montreal, Quebec, Canada, H2W 1T8
Sacre-Coeur Hospital
Montreal, Quebec, Canada, H4J1C5
Centre de Sante et de services sociaux du nord de lanaudiere/CHRDL
St. Charles-Borromee, Quebec, Canada, J6E6J2
Centre Hospitalier Beauce-Etchemin
St. George, Quebec, Canada, G5Y5B7
Clinique de Cardiologie de Trois-Rivieres
Trois Rivieres, Quebec, Canada, G8Z 3R9
Cardiology and Research
Westmount, Quebec, Canada, H3Z2M6
Centre Hospitalier Universitaire de Quebec (CHOQ) Hotel Dieu de Quebec
Quebec, Canada, G1R2J6
Laval Hospital
Quebec, Canada, G1V4G5
Clinica Antofagasta
Antofagasta, Chile
Corporación de Beneficencia Osorno
Osorno, Chile
Hospital Regional de Punta Arenas Dr. Lautaro Navarro
Punta Arenas, Chile
Complejo Asistencial Dr.Sótero del Río
Santiago, Chile, 8207257
Hospital del Salvador
Santiago, Chile
Instituto Nacional del Tórax
Santiago, Chile
Centro de Estudios Cardiovascular
Temuco, Chile
Clínica Reñaca
Viña del Mar, Chile
Hospital Dr. Gustavo Fricke
Viña del Mar, Chile
Hospital Naval Almirante Neff
Viña del Mar, Chile
Czech Republic
Nemocnice ve Frydku-Mistku
Frydek-Mistek, Czech Republic, 738 18
Fakultni nemocnice Hradec Kralove
Hradec Kralove, Czech Republic, 500 05
Krajska nemocnice Liberec, a. s.
Liberec, Czech Republic, 460 63
Litomyslska nemocnice a. s.
Litomysl, Czech Republic, 570 14
Kardiologicka a angiologicka ambulance
Ostrava Vítkovice, Czech Republic, 703 00
Kardiologická ambulance
Ostrava, Czech Republic, 702 00
Pardubicka krajska nemocnice, a.s.
Pardubice, Czech Republic, 532 03
II.interni klinika kardiologie a angiologie 1. LF UK a VFN v Praze
Praha 2, Czech Republic, 12808
Klinika kardiologie Institut klinické a experimentální medicíny
Praha 4, Czech Republic, 140 21
Krajská nemocnice T. Bati a.s.
Zlín, Czech Republic, 762 75
Nemocnice Znojmo, p.o.
Znojmo, Czech Republic, 669 02
Centre Hospitalier d'Albi
Albi, France, 81000
Centre de Cardiologie CHRU Dijon
Dijon Cedex, France, 21079
Clinique Pasteur
Essey les Nancy Cedex, France, 54270
CHRU de Lille Hôpital Cardiologique
Lille Cedex, France, 59037
Hôpital La Timone-Adultes
Marseille, France, 13385
La Pitié Salpétrière Institut de Cardiologie
Paris Cedex 13, France, 75651
Hôpital Lariboisière
Paris, France, 75010
Centre Hospitalier Intercommunal du Val d'Ariège
St Jean de Verges, France, 09000
Centre Hospitalier Rangueil Larrey
Toulouse Cedex 4, France, 31403
Universitatsklinikum Berlin Campus Charite Mitte Med Klinik Kardiologie und Angiologie
Berlin, Germany, 10117
Vivantes Clinic Neuköln Berlin
Berlin, Germany, 12351
Vivantes Humbolt Klinikum
Berlin, Germany, 13509
Praxis Dr. med. Boscher
Biberach, Germany, 88400
St. Josef-Hospital Medizinische Klinik II, Kardiologie
Bochum, Germany, 44791
Dr. THomas Klingenheben
Bonn-Lengsdorf, Germany, 53127
St.-Marien-Hospital Bonn
Bonn, Germany, 53115
Städtisches Klinikum Brandenburg GmbH
Brandenburg, Germany, 14770
MVZ am Küchwald GmbH
Chemnitz, Germany, 09113
Gemeinschaftspraxis Innere Medizin und Kardiologie
Dinslaken, Germany, 46535
St.-Johannes-Hospital Dortmund
Dortmund, Germany, 44137
Zentrum für klinische Prüfungen in der Facharztzentrum Dresden Neustadt GbR
Dresden, Germany, 1099
Practice of Cardiology
Erfurt, Germany, 990804
Essen, Germany, 45138
Asklepios Klinik St.Georg
Hamburg, Germany, 20099
Asklepios Klinik Barmbek
Hamburg, Germany, 22291
Universitäres Herz-und Gefäßzentrum Hamburg"
Hamburg, Germany, 22527
Kardiologische Praxis Hamburg Altona
Hamburg, Germany, 22765
Klinikum Region Hannover Krankenhaus Nordstadt
Hannover, Germany, 30167
Kardiologische Gemeinschaftspraxis
Hartmannsdorf, Germany, 09232
SRH Klinikum Karlsbad-Langensteinbach
Karlsbad, Germany, 76307
Kliniken der Stadt Köln, Köln Merheim
Koln, Germany, 53109
Herzzentrum Lahr
Lahr, Germany, 77933
Kardiologische Gemeinschaftpraxis
Leipzig, Germany, 04103
Universität Leipzig - Herzzentrum
Leipzig, Germany, 04289
Praxis für Innere Medizin, Gastroenterologie
Ludwigshafen, Germany, 67067
Universitätsklinikum Lübeck
Lübeck, Germany, 23538
Lüneburg, Germany, 21339
Klinikum der Johannes-Gutenberg-Universität
Mainz, Germany, 55131
Mannheim, Germany, 68165
Klinikum Mannheim GmbH, Universaitatskinikum
Mannheim, Germany, 68167
Kardiologische Praxis
Markkleeberg, Germany, 04416
Asklepios Klinik Melsungen
Melsungen, Germany, 34212
Kilniken Maria Hilf GmbH Krankenhaus St. Franziskus
Mönchengladbach, Germany, 41063
Mühldorf a.d. Inn, Germany, 84453
Kardiologische Gemeinschaftspraxis
Nienburg, Germany, 31582
Klinikum Pirna GmbH
Pirna, Germany, 01796
Universitätsklinik Regensburg
Regensburg, Germany, 93053
Krankenhaus Reinbek St. Adolf-Stift
Reinbek, Germany, 21465
Kardiologische Gemeinschaftspraxis
Riesa, Germany, 01589
Internistische Praxis
Rottweil, Germany, 78628
Zentrum für Prävention und Rehabilation
Siegen, Germany, 57072
Marienkrankenhaus Soest
Soest, Germany, 59494
Praxisgemeinschaft Stuhr-Brinkum
Stuhr, Germany, 28816
Medizinische Universitätsklinik
Tubingen, Germany, 72076
Josephs-Hospital Warendorf
Warendorf, Germany, 48231
Kardiologische Praxis
Wermsdorf, Germany, 04779
Dr. Andreas Schreckenberg
Weyhe-Leeste, Germany, 28844
ForschungsZentrum Ruhr
Witten, Germany, 58455
Helios Klinikum Wuppertal
Wuppertal, Germany, 42117
Bajai Kórház
Baja, Hungary, H-6500
Budai Irgalmasrendi Kórház
Budapest, Hungary, H-1027
Fővárosi Önkormányzat Károlyi Sándor Kórház és Rendelőintézet
Budapest, Hungary, H-1041
Fovarosi Onkormanyzat Egyesitett Szent Istvan es Szent Laszlo Korhaz - Rendelointezet
Budapest, Hungary, H-1096
Városi Önkormányzat Kórház-Rendelőintézet
Kalocsa, Hungary, H-6300
Szabolcs-Szatmár-Bereg Megyei Önkormányzat Jósa András Oktató Kórház
Nyíregyháza, Hungary, H-4400
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház
Toszegi, Hungary, H-5004
Jávorszky Ödön Kórház
Vác, Hungary, H-2600
Zala Megyei Kórház
Zalaegerszeg, Hungary, H-8900
Ospedali Riuniti di bergamo
Bergamo, Italy, 24128
Azienda Ospedaliera della Provincia di Lodi Presidio Ospedaliero di Codogno
Codogno (Lodi), Italy, 26845
Azienda Ospedaliera Universitaria San Martino-Dipartimento di Medicina Interna e Specialità Mediche
Genova, Italy, 16132
Azienda Ospeedaliera Carlo Poma
Mantova, Italy, 46100
Azienda Ospedaliera Maggiore Della Carita' Di Novara
Novara, Italy, 28100
Istituto Clinico Humanitas
Rozzano (Milano), Italy, 20089
Hospital "Valentín Gómez Farías"
Guadalajara, Jalisco, Mexico, 44600
Cardioarritmias e Investigación, S.C.
San Luis Potosi, San Lusi Potosi, Mexico, 78200
Hospital Cardiológica Aguascalientes
Aguascalientes, Mexico, 20230
Hospital de Jesus
D. F., Mexico, cp 06090
Durango, Mexico, C. P 34080
Hospital Angeles de Puebla
Puebla, Mexico, 72190`
Hospital General de Puebla
Puebla, Mexico, 72490
Instituto de Corazón de Querétaro, S.A. de C.V.
Queretaro, Mexico, 76178
Hospital Central "Dr. Ignacio Morones Prieto"
San Luis Potosi, Mexico, 78240
Oddział Kardiologii z Zakładem Diagnostyki Kardiologicznej, Samodzielny Publiczny Zakład Opieki Zdrowotnej, Wojewódzki Szpital im. dr J. Biziela,
Bydgoszcz, Poland, 85-168
NZOZ "Medicus" Jacek Kubica
Bydgoszcz, Poland, 85-435
Wojewódzki Szpital Meijski im. Biziela, Oddział Kardiologii - SPZOZ
Bydgoszcz, Poland, 85-826
Oddział Chorób Wewnętrzych i Kardiologii , ZOZ w Debicy
Dębica, Poland, 39-200
Zakład Opieki Zdrowotnej Trójmiejskie Centrum Medyczne Sp. z o.o
Gdańsk, Poland, 80-437
Gabinet Kardiologiczny Medipuls
Gdynia, Poland, 81-423
Gabinet Kardiologiczno-Internistyczny
Gdynia, Poland, 81-472
Centrum Leczenia Chorób Cywilizacyjnych Oddz. Gdynia filla Fikakowo
Gdynia, Poland, 81-572
NZOZ Medicus, Poradnia Kardiologiczna
Gliwice, Poland, 44-100
Oddział Kardiologii i INK, SPZOZ nr 1
Gliwice, Poland, 44-100
Mazowieckie Centrum Badań Klinicznych Iwona Czajkowska, Monika Śmietańska s.c.
Grodzisk Mazowiecki, Poland, 05-825
Publiczny Specjalistyczny Zaklad Opieki Zdrowotnej Oddzial Kardiologiczny
Inowroclaw, Poland, 88-100
Oddział Chorób Wewnętrznych i Farmakologii Klinicznej Samodzielny Publiczny Centralny Szpital Kliniczny im. Prof. Kornela Gibińskiego Śląskiego Uniwersytetu Medycznego w Katowicach
Katowice, Poland, 40-752
Szpital Specjalistyczny w Kościerzynie, Oddział Kardiologii
Kościerzyna, Poland, 83-400
Oddział Kardiologii, Szpital Specjalistyczny im. J. Dietla
Krakow, Poland, 31-121
"Klinika Choroby Wieńcowej Instytut Kardiologii, Collegium Medicum Uniwerytet Jagielloński
Krakow, Poland, 31-202
Oddzial Chorób Wewnętrznych III Szpital Specjalistyczny im.Stefana Zeromskiego, SPZOZ w Krakowie
Kraków, Poland, 31-913
Niepubliczny Zakład Opieki Zdrowotnej Specjalista Sp. z o.o.
Kutno, Poland, 99-300
Poradnia Kardiologiczna, Oddział Chorob Wewnetrznych Szpital Powiatowy w Limanowej
Limanowa, Poland, 34-600
Oddział Internistyczno-Kardiologiczny Samodzielny Publiczny Zakład Opieki Zdrowotnej
Lubartów, Poland, 21-100
"Oddzial Chorob Wewnetrznych i Kardiologii, Szpital Powiatowy im.Edmunda Biernackiego
Mielec, Poland, 39-300
Oddział Kardiologii, Nowa Sól
Nowa Sól, Poland, 67-100
ZOZ w Oławie, Oddział Chorób Wewnętrznych
Olawa, Poland, 55-200
"Oddział Kardiologiczno-Internistyczny
Olsztyn, Poland, 10-045
"Oddział Kardiologiczny Publiczny Samodzielny ZOZ Wojewódzkie Centrum Medyczne
Opole, Poland, 45-418
Specjalistyczny Zakład Opieki Zdrowotnej Poradnia lekarzy specjalistów "Jantar"
Ostrów Wielkopolski, Poland, 63-400
II Oddział Wewnętrzny Samodzielny Publiczny Zakład Opieki Zdrowotnej
Pabianice, Poland, 95-200
"Samodzielny Szpital Wojewódzki im. Mikołaja Kopernika, Oddział Kardiologiczny
Piotrków Trybunalski, Poland, 97-300
Medyczne Centrum Hetmańska, Indywiualna Specjalistyczna Praktyka Lekarska, Dr n. med. Piotr Leszczyński
Poznań, Poland, 60-218
Specjalistyczne Centrum Diagnostyczno-Lecznicze Bamberski Dwór
Poznań, Poland, 60-539
Oddział Wewnetrzny I, Szpital Kolejowy im. dr med. Włodzimierza Roeslera
Pruszków, Poland, 05-800
Samodzileny Publiczny Zakład Opieki Zdrowotnej w Puławach, Szpital Specjalistyczny
Puławy, Poland, 24-100
Wojewódzki Szpital Zespolony, Oddział Kardiologiczny
Płock, Poland, 09-400
Specjalistyczna Przychodnia Lekarska "Medikard"
Płock, Poland, 09-402
Zakład Hemodynamiki, Wojewódzki Szpital Specjalistyczny
Radom, Poland, 26-617
"Oddział Kardiologii z Pododdziałem Ostrych Zespołów Wieńcowych i z Ośrodkiem Implantacji Rozruszników Serca,
Rzeszów, Poland, 35-301
Oddział Kardiologii, SP ZZOZ Sandomierz
Sandomierz, Poland, 27-600
Oddział Kardiologiczny Wojewódzki Szpital Specjalistyczy w Siedlcach
Siedlce, Poland, 08-110
Oddział Kardiologii Samodzielny Publiczny Zakład Opieki Zdrowotnej w Sieradzu im. Kardynała Stefana Wyszyńskiego
Sieradz, Poland, 98-200
"Oddział Kardiologii, Wojewódzki Szpital Zespolony w Skierniewicach, "
Skierniewice, Poland, 96-100
NZOZ Przychodnia Zadebie, Przychodnia Kardiologiczna
Skierniewice, Poland, 96-100
"Oddział Kardiologii Inwazyjnej i Angiologii z Pr. Hemodynamiki
Stalowa Wola, Poland, 37-450
Szpital Specjalistyczny Św.Jana, Oddział Kardiologii,
Starogard Gdański, Poland, 83-200
Indywidualna Specjalistyczna Praktyka Lekarska
Szczecin, Poland, 71-531
Poradnia Kardiologiczna
Tarnów, Poland, 33-100
Specjalistyczny Gabinet Lekarski Internistyczno-Kardiologiczny-Cardiology
Tarnów, Poland, 33-100
Niepubliczny Zakład Opieki Zdrowotnej "Nasz Lekarz", Praktyka Grupowa Lekarzy Rodzinnych z Przychodnią Specjalistyczną
Torun, Poland, 87 100
Oddział Kardiologii Wojewódzki Szpital Zespolony
Toruń, Poland, 87-100
Oddział Kardiologiczny Szpital Wolski im. dr Anny Gostyńskiej Samodzielny Publiczny Zakład Opieki Zdrowotnej
Warszawa, Poland, 01 - 211
Samodzielny Publiczny Centralny Szpital Kliniczny Akademii Medycznej w Warszawie
Warszawa, Poland, 02-097
II Klinika Choroby Wieńcowej Instytutu Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
Warszawa, Poland, 02-637
Centrum Leczenia Chorób Cywilizacyjnych
Warszawa, Poland, 02-777
Międzyleski Szpital Specjalistyczny w Warszawie
Warszawa, Poland, 04-749
NZOZ Starówka
Warszawa, Poland
"Oddział Kardiologiczny Wałbrzyski Ośrodek Kardiologii Interwencyjnej Specjalityczny Szpital im. Dr Alfreda Sokołowskiego
Wałbrzych, Poland, 58-309
Osrodek Chorob Serca, Klinika Kardiologii 4 Wojskowy Szpital Kliniczny z Poliklinika - Samodzielny Publiczny Zaklad Opieki Zdrowotnej
Wroclaw, Poland, 50-981
Synexus SCM Sp.z o o.
Wrocław, Poland, 50-088
Niepubliczny Zakład Opieki Zdrowotnej, Centrum Badań Klinicznych
Wrocław, Poland, 50-349
"Śląskie Centrum Chorób Serca, III Katedra i Oddział Kliniczny Kardiologii Śląskiego Uniwersytetu Medycznego
Zabrze, Poland, 41-800
Oddział Kardiologiczny Szpital Wojewódzki im. Kardynała Stefana Wyszyńskiego
Łomża, Poland, 18-404
Niepubliczny Zakład Opieki Zdrowotnej POLIMEDICA
Łódź, Poland, 90-302
All-Med Centrum Medyczne
Łódź, Poland, 94-050
Puerto Rico
Research and Cardiovascular Corp.
Ponce, Puerto Rico, 00717-1322
Spitalul Clinic Judetean de Urgenta Bacau
Bacau, Romania, 600114
S.C. Duo Medical S.R.L.
Bucharest, Romania, 010584
Cardiomed SRL
Bucharest, Romania, 020506
Centrul Medical SANA
Bucuresti, Romania, 011025
Institutul Inimii "Niculae Stanicioiu"
Cluj-Napoca, Romania, 400001
Cardiomed SRL
Craiova, Romania, 200147
Dr. C.I. Parhon Hospital
Iasi, Romania, 700503
Clinical county Hospital
Sibiu, Romania, 550245
Institutul de Boli Cardiovasculare si Transplan Tg. Mures
Targu Mures, Romania, 540136
County Hospital
Timisoara, Romania, 300736
Novamed s.r.o.
Banská Bystrica, Slovakia, 97405
Alian s.r.o.
Bardejov, Slovakia, 085-01
5. Interna klinika LF UK, FNsP Bratislava, Nemocnica Ruzinov
Bratislava, Slovakia, 826 06
Cardio D&R spol. s r.o.
Kosice, Slovakia, 040-22
Kardiomed s.r.o.
Lučenec, Slovakia, 98401
NZZ Kardiocentrum Nitra s.r.o.
Nitra, Slovakia, 950-01
MUDr. Tibor DURIS, CSc., s.r.o.
Nove Zamky, Slovakia, 94052
Nemocnica s poliklinikou Považská Bystrica
Považská Bystrica, Slovakia, 017 26
Fakultna Nemocnica Trencin
Trencin, Slovakia, 911 71
Žilpo s.r.o.
Žilina, Slovakia, 010 01
Medivasa s.r.o.
Žilina, Slovakia, 010-01
"Klinichne obyednannia shvydkoi medychnoi dopomogy, m. Dnipropetrovs'k,Dnipropetrovs'ka derzhavna medychna akademiya, kafedra gospital'noi terapii #2
Dnipropetrovsk, Ukraine, 49006
Oblasnyi klinichnyi kardiologichnyi dyspanser, m. Ivano-Frankivsk, Ivano-Frankivskyi derzhavnyi medychnyi universytet, kafedra terapii # 3
Ivano-Frankivsk, Ukraine, 76005
TOV "Kardiologichna klinika "Sertse i sudyny" m. Kyiv
Kyiv, Ukraine, 1032
Natsionalnyi naukovyi tsentr "Instytut kardiologii im. akad. M.D. Strazheska" AMN Ukrainy, m. Kyiv, viddilenia symptomatychnykh arterial'nykh gipertenziy
Kyiv, Ukraine, 3680
Natsionalnyi naukovyi tsentr "Instytut kardiologii im. akad. M.D. Strazheska", viddil reanimatsii ta intensyvnoi terapii, m. Kyiv
Kyiv, Ukraine, 3680
Komunal'na ustanova "Oblasnyi kardiologichnyi dyspanser", viddilenia intensyvnoi terapii, m. Zaporizhzhia
Zaporizhzhya, Ukraine, 69000
Kardioarytmologichnyi tsentr Zhytomyrs'koi oblasnoi klinichnoi likarni im. O.F. Gorbachevs'kogo, m. Zhytomyr
Zhytomyr, Ukraine, 10002
Sponsors and Collaborators
Cogentus Pharmaceuticals
Study Director: Pablo Lapuerta, MD Cogentus Pharmaceuticals

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Pablo Lapuerta, MD, Cogentus Pharmaceuticals Identifier: NCT00557921     History of Changes
Other Study ID Numbers: CG104
EudraCT 2007-005891-15
First Posted: November 14, 2007    Key Record Dates
Last Update Posted: January 28, 2009
Last Verified: January 2009

Keywords provided by Cogentus Pharmaceuticals:
acute coronary syndrome
cerebrovascular disorders
coronary artery stent placement
coronary thrombosis
myocardial infarction
myocardial ischemia
percutaneous coronary intervention
percutaneous transluminal coronary angioplasty
peripheral vascular diseases
duodenal obstruction
duodenal ulcer
esophagitis, peptic
gastric outlet obstruction
gastroduodenal ulcer
gastroesophageal reflux disease
gastrointestinal hemorrhage
peptic ulcer
peptic ulcer perforation

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Myocardial Infarction
Acute Coronary Syndrome
Pathologic Processes
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Inflammatory Agents
Antirheumatic Agents
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
Platelet Aggregation Inhibitors