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Psoriasis Longitudinal Assessment and Registry (PSOLAR)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Identifier: NCT00508547
Recruitment Status : Recruiting
First Posted : July 30, 2007
Last Update Posted : November 1, 2019
Information provided by (Responsible Party):
Janssen Scientific Affairs, LLC

Brief Summary:
The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and guselkumab in patients with plaque psoriasis, and other all forms of psoriasis (such as plaque psoriasis and psoriatic arthritis occurring together). The registry study will track the behavior of the disease in response to other therapies, such as other biologic drugs. The registry will also evaluate clinical outcomes; disease characteristics, including physician reported assessment of psoriatic arthritis (PsA); quality of life, and potential risks for patients who may receive standard therapies for psoriasis.

Condition or disease Intervention/treatment
Psoriasis Arthritis, Psoriatic Biological: Ustekinumab Biological: Biological therapies other than infliximab, ustekinumab and guselkumab Drug: Conventional systemic agents Biological: Infliximab Biological: Guselkumab

Detailed Description:
PSOLAR is an 8 year registry study. A registry is an observational study that evaluates the status of a disease. This registry study will only include patients who volunteer to take part. About 4000 infliximab-exposed patients, 4000 ustekinumab-exposed patients and as well as a comparable number of patients (4000) on other standard of care psoriasis therapies (e.g. Etanercept) and/or psoriasis treatments (e.g. topical or light therapy treatments) will take part in the registry study, internationally. Additionally, enrollment will be opened to include at least 2,000 guselkumab-exposed patients and up to 2,000 patients exposed to IL-17 inhibitors (example, secukinumab, ixekizumab, brodalumab). The Registry does not require any study-specific testing, but may capture test information (e.g. laboratory tests, X-rays) that are collected as part of normal routine care for the registry program. Patient information will be collected at the enrollment visit and about every 6 months thereafter. At enrollment, information on demographics (e.g. gender, race, date of birth), medical history and family medical history, details of past and current psoriasis treatments (e.g. infliximab and standard therapy), and current medication regimens will be collected. Clinical follow-up will be based on observations from physical examination, clinical disease status, Quality of Life assessment (e.g. Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, EQ-5D (EuroQoL-5D is a Quality of Life Questionnaire) Health Questionnaire Scale, Employment/Productivity Health Economic Questionnaire), current medications, and any adverse events/problems reported. During each six -month follow-up visit with the study doctor, information collected will include observations from physical examination, updates on clinical disease status, Quality of life assessments, medications and adverse events/problems. No study agents will be administered in this registry. All patients will receive standard of care treatments prescribed by the patient's physician.

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Study Type : Observational
Estimated Enrollment : 16000 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics
Actual Study Start Date : June 21, 2007
Estimated Primary Completion Date : May 31, 2021
Estimated Study Completion Date : April 19, 2030

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
Participants will receive guselkumab as prescribed by the physician according to standard of care for psoriasis.
Biological: Guselkumab
Guselkumab will be administered as prescribed by physician.

Participants will receive infliximab as prescribed by the physician according to standard of care for psoriasis.
Biological: Infliximab
Infliximab will be administered as prescribed by physician.

Participants will receive ustekinumab as prescribed by the physician according to standard of care for psoriasis.
Biological: Ustekinumab
Ustekinumab will be administered as prescribed by physician.

Biological Therapies
Participants will receive biological therapies other than infliximab, ustekinumab and guselkumab as prescribed by physician for psoriasis. Participants will not receive any intervention as a part of this study.
Biological: Biological therapies other than infliximab, ustekinumab and guselkumab
Biological therapies will be administered as prescribed by physician.

Conventional Systemic Agents
Participants will receive conventional systemic agents as prescribed by physician for psoriasis. Participants will not receive any intervention as a part of this study.
Drug: Conventional systemic agents
Conventional systemic agents will be administered as prescribed by physician.

Primary Outcome Measures :
  1. Number of patients with Adverse Events and Serious Adverse Events [ Time Frame: 8 years from last patient enrolled ]
    An AE is any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. An SAE is an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life-threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. All adverse events, including those of special interest, such as dysplasias and malignancies of all types, serious infections, and new autoimmune disease, will be documented.

Secondary Outcome Measures :
  1. Physician reported plaque psoriasis and psoriatic arthritis (PsA) Score [ Time Frame: every 6 months for 8 years ]
  2. Dermatology Life Quality Index (DLQI) Score [ Time Frame: every 6 months for 8 years ]
  3. EuroQOL quality of life assessment [ Time Frame: every 6 months for 8 years ]
  4. Hospital Anxiety and Depression Scale (HADS) Score [ Time Frame: every 6 months up to Month 18 and then every year up to 8 years ]
  5. Percentage of patients being treated that meets labeling criteria [ Time Frame: every 6 months for 8 years ]
  6. Percentage of participants with comorbidities: cardiovascular disease [ Time Frame: Day 1 ]
  7. Percentage of participants with comorbidities: malignancy [ Time Frame: Day 1 ]
  8. Burden of Disease: Body surface area [ Time Frame: every 6 months for 8 years ]
  9. Burden of Disease: Psoriasis Area and Severity Index (PASI) Score [ Time Frame: every 6 months for 8 years ]
  10. Evaluation of disease features: Physicians global assessment of disease activity (PGA) Score [ Time Frame: every 6 months for 8 years ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 99 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Any patients with psoriasis that meets the inclusion criteria will be eligible to participate in this registry.

Inclusion Criteria:

  • Have a diagnosis of psoriasis
  • Are candidates for, or are currently receiving conventional systemic agents (eg, methotrexate, acitretin, cyclosporine or systemic psoralen drug in combination with Ultraviolet A light [PUVA]) or biologic therapy for psoriasis including those with chronic severe (extensive and/or disabling) plaque psoriasis who may be treated with infliximab or those with moderate to severe plaque psoriasis who may be treated with ustekinumab, guselkumab, or another biologic agent
  • Ability to understand and sign an informed consent form
  • Are willing to participate in regular follow-up visits

Exclusion Criteria:

  • Refuse to consent or are unwilling to respond to request for a long term information within the required time frame
  • Are participating or have already planned to participate in a clinical trial with non-marketed investigational agents or are participating in a Centocor-sponsored clinical trial with marketed agents

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00508547

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Contact: Use link at the bottom of the page to see if you qualify for an enrolling site (see list). If you still have questions:

  Hide Study Locations
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United States, Alabama
Total Skin & Beauty Dermatology Center Active, not recruiting
Birmingham, Alabama, United States, 35205
University of Alabama - Dermatology Completed
Birmingham, Alabama, United States, 35233
Tennessee River Dermatology Completed
Florence, Alabama, United States, 35630
Northeast Dermatology Active, not recruiting
Huntsville, Alabama, United States, 35801
Ruth A. Yates M.D. Active, not recruiting
Huntsville, Alabama, United States, 35801
Horizon Research Withdrawn
Mobile, Alabama, United States, 36608
United States, Arizona
Alliance Dermatology and MOHS Center, P.C. Active, not recruiting
Phoenix, Arizona, United States, 85032
Affiliated Dermatology Completed
Scottsdale, Arizona, United States, 85255
Arizona Dermatology & Cosmetic Dermatology Pc Active, not recruiting
Scottsdale, Arizona, United States, 85255
Sheftel Dermatology Completed
Tucson, Arizona, United States, 85718
United States, Arkansas
NW Arkansas Clinical Trials Center, PLLC Active, not recruiting
Rogers, Arkansas, United States, 72758
United States, California
Bakersfield Dermatology Active, not recruiting
Bakersfield, California, United States, 93309
Paul Wallace MD Active, not recruiting
Beverly Hills, California, United States, 90211
Sierra Medical Research Completed
Clovis, California, United States, 93612
Cosmetic & Laser center Active, not recruiting
Fountain Valley, California, United States, 92708
Edwin M. Hamlin M.D. Active, not recruiting
Fresno, California, United States, 93720
Loma Linda Univ Faculty Medic Active, not recruiting
Loma Linda, California, United States, 92354
Clinica Medica San Miguel Completed
Los Angeles, California, United States, 90015
Dermatology Research Associates Active, not recruiting
Los Angeles, California, United States, 90045
Menkes Cosmetic Dermatology Completed
Mountain View, California, United States, 94040
The Dermatology Medical Group of Oxnard and Camarillo Active, not recruiting
Oxnard, California, United States, 93036
Redding Dermatology Active, not recruiting
Redding, California, United States, 96001
Palos Verdes Dermatology Active, not recruiting
Rolling Hills Estates, California, United States, 90274
MedDerm Associates Active, not recruiting
San Diego, California, United States, 92103
University Clinical Trials, Inc. Active, not recruiting
San Diego, California, United States, 92103
Therapeutics Clinical Research Active, not recruiting
San Diego, California, United States, 92123
East Bay Psoriasis Treatment Center Active, not recruiting
San Ramon, California, United States, 94583
Dermatology Institute and Skin Care Center, Inc. Active, not recruiting
Santa Monica, California, United States, 90404
MD Solutions Medical Corp Completed
Sherman Oaks, California, United States, 91403
Skin Physicians & Surgeons Active, not recruiting
Upland, California, United States, 91786
Solano Dermatology Associates Active, not recruiting
Vallejo, California, United States, 94590
United States, Colorado
Colorado Springs Dermatology Clinic, PC Active, not recruiting
Colorado Springs, Colorado, United States, 80910
Dermatology Associates Of Colorado Pc Active, not recruiting
Englewood, Colorado, United States, 80112
United States, Connecticut
Kenneth J. Maiocco, M.D. Active, not recruiting
Bridgeport, Connecticut, United States, 06606
University of Connecticut Active, not recruiting
Farmington, Connecticut, United States, 06030
United States, Delaware
Burke Dermatology Completed
Newark, Delaware, United States, 19713
Panzer Dermatology Associates, Pa Completed
Newark, Delaware, United States, 19713
Delaware Valley Dermatology Active, not recruiting
Wilmington, Delaware, United States, 19810
United States, District of Columbia
George Washington University Active, not recruiting
Washington, District of Columbia, United States, 20037
United States, Florida
Horwitz Dermatology Active, not recruiting
Aventura, Florida, United States, 33180
Tory P. Sullivan, M.D., PA Active, not recruiting
Aventura, Florida, United States, 33180
VA Healthcare System Bay Pines Active, not recruiting
Bay Pines, Florida, United States, 33744
Weiss Skin Institute Completed
Boca Raton, Florida, United States, 33428
Dermatology of Boca, LLC Completed
Boca Raton, Florida, United States, 33431
Study Protocol Inc. Completed
Boynton Beach, Florida, United States, 33437
Dermatology Associates In Research Completed
Coral Gables, Florida, United States, 33134
Florida Academic Dermatology Centers Active, not recruiting
Coral Gables, Florida, United States, 33134
Brent M. Schillinger, MD, PA Completed
Delray Beach, Florida, United States, 33483
Virginia Street Dermatology Active, not recruiting
Dunedin, Florida, United States, 34698
Hollywood Dermatology and Cosmetic Surgery Active, not recruiting
Hollywood, Florida, United States, 33021
Michael J. Bernhardt, M.D., P.A. Withdrawn
Jacksonville, Florida, United States, 32207
Ameriderm Research Completed
Jacksonville, Florida, United States, 32256
MIMA Completed
Melbourne, Florida, United States, 32940
University of Miami - Miller School of Medicine Completed
Miami, Florida, United States, 33136
Advanced Pharma Clinical Research Withdrawn
Miami, Florida, United States, 33175
Associates in Medical & Surgical Completed
Naples, Florida, United States, 34109
Wayne R Porter, MD PA Completed
North Miami Beach, Florida, United States, 33162
Park Avenue Dermatology Withdrawn
Orange Park, Florida, United States, 32073
Gulfcoast Dermatology Completed
Panama City, Florida, United States, 32405
Snyder and Le, MD, PA Active, not recruiting
Pembroke Pines, Florida, United States, 33028
Armstrong Dermatology and Skin Cancer Center, PA Active, not recruiting
Seminole, Florida, United States, 33776
Michael A. Scannon, MD, PC Active, not recruiting
Tampa, Florida, United States, 33607
Academic Alliance in Dermatology Inc Active, not recruiting
Tampa, Florida, United States, 33609
Forman Dermatology Completed
Tampa, Florida, United States, 33624
United States, Georgia
Dermatology Vein Institute Active, not recruiting
Alpharetta, Georgia, United States, 30022
Dermatology Consultants PC Withdrawn
Atlanta, Georgia, United States, 30309
Dermatology Associates of Atlanta Active, not recruiting
Atlanta, Georgia, United States, 30342
Inverness Dermatology Active, not recruiting
Birmingham, Georgia, United States, 35242
Skin Cancer and Cosmetic Dermatology Withdrawn
Calhoun, Georgia, United States, 30701
David E Schoenfeld M.D., PC Active, not recruiting
Carrollton, Georgia, United States, 30117
East Metro Dermatology Active, not recruiting
Conyers, Georgia, United States, 30012
Family Dermatology, PC Completed
Lilburn, Georgia, United States, 30047
Dermatologic Surgery Specialists Active, not recruiting
Macon, Georgia, United States, 31217
John David Kayal, MD Active, not recruiting
Marietta, Georgia, United States, 30060
Northwest Georgia Dermatology Active, not recruiting
Rome, Georgia, United States, 30165
St. Joseph's Candler Health System Withdrawn
Savannah, Georgia, United States, 31405
United States, Idaho
Alan Olmstead, MD, CHTD Active, not recruiting
Twin Falls, Idaho, United States, 83301
United States, Illinois
Christie Clinic Completed
Champaign, Illinois, United States, 61820
Northwestern Active, not recruiting
Chicago, Illinois, United States, 60611
SKINQRI Completed
Lincolnshire, Illinois, United States, 60069
Loyola University Medical Center Active, not recruiting
Maywood, Illinois, United States, 60153
Altman Dermatology Associates Active, not recruiting
Rolling Meadows, Illinois, United States, 60008
Schaumburg Dermatology Completed
Schaumburg, Illinois, United States, 60194
Evanston Northwestern Healthcare Active, not recruiting
Skokie, Illinois, United States, 60077
SIU School of Medicine Active, not recruiting
Springfield, Illinois, United States, 62702
Dundee Dermatology Completed
West Dundee, Illinois, United States, 60118
Central Dupage Hospital Active, not recruiting
Winfield, Illinois, United States, 60190
United States, Indiana
Deaconess Clinic Mt. Pleasant Active, not recruiting
Evansville, Indiana, United States, 47713
Indiana University Medical Center Active, not recruiting
Indianapolis, Indiana, United States, 46202
Dawes Fretzin Clinical Research Group, LLC Active, not recruiting
Indianapolis, Indiana, United States, 46250
A. David Gerstein, M.D. Withdrawn
Indianapolis, Indiana, United States, 46260
The Dermatology Center PSC Active, not recruiting
New Albany, Indiana, United States, 47150
Indiana Clinical Trial Center, PC Active, not recruiting
Plainfield, Indiana, United States, 46168
Randall Dermatology & Cosmetic Surgery Completed
West Lafayette, Indiana, United States, 47906
United States, Kansas
Kansas Medical Clinic Active, not recruiting
Topeka, Kansas, United States, 66614
United States, Kentucky
Dr Melissa Knuckles Active, not recruiting
Corbin, Kentucky, United States, 40701
Mapi Group Recruiting
Lexington, Kentucky, United States, 40504
United States, Louisiana
Tulane Un. Health Science Ctr. Dept. of Dermatology Active, not recruiting
New Orleans, Louisiana, United States, 70112
United States, Maryland
David Strobel, M.D. Withdrawn
Catonsville, Maryland, United States, 21228
Greater Washington Dermatology Withdrawn
Rockville, Maryland, United States, 20850
Lawrence R. Feldman, M.D. Withdrawn
Westminster, Maryland, United States, 21157
United States, Massachusetts
Tufts-New England Medical Center Active, not recruiting
Boston, Massachusetts, United States, 02111
Clinical Unit for Research Trials in Skin Active, not recruiting
Boston, Massachusetts, United States, 02114
The Brigham and Women's Hospital, Inc. Completed
Boston, Massachusetts, United States, 02115
Kenneth M Reed MD PC Active, not recruiting
Quincy, Massachusetts, United States, 02169
United States, Michigan
David Fivenson MD, Dermatology Active, not recruiting
Ann Arbor, Michigan, United States, 48103
Clarkston Dermatology & Vein Center, PLLC Completed
Clarkston, Michigan, United States, 48346
Drs Iacobelli & DiGregorio PC Active, not recruiting
Clinton Township, Michigan, United States, 48038
Barry I Auster, MD, PC Completed
Farmington, Michigan, United States, 48334
Dr. Walter Barkey Active, not recruiting
Flint, Michigan, United States, 48507
Hamzavi Dermatology Active, not recruiting
Fort Gratiot, Michigan, United States, 48059
Silverton Skin Institute Completed
Grand Blanc, Michigan, United States, 48439
Dermatology Center of Grand Rapids Active, not recruiting
Grand Rapids, Michigan, United States, 49503
Skincare Associates PC Active, not recruiting
Monroe, Michigan, United States, 48162
Lakeshore Dermatology Laser & Medical Spa Active, not recruiting
Norton Shores, Michigan, United States, 49444
Somerset Skin Centre Completed
Troy, Michigan, United States, 48084
Grekin Skin Institute Completed
Warren, Michigan, United States, 48088
United States, Minnesota
Dermatology Center for Children & Young Adults Completed
Eagan, Minnesota, United States, 55121
United States, Missouri
West County Dermatology Inc. Active, not recruiting
Chesterfield, Missouri, United States, 63017
St. Louis University Active, not recruiting
Saint Louis, Missouri, United States, 63104
Central Dermatology Active, not recruiting
Saint Louis, Missouri, United States, 63117
United States, Montana
Associated Dermatology Active, not recruiting
Helena, Montana, United States, 59601
United States, Nevada
Woodson Dermatology Active, not recruiting
Henderson, Nevada, United States, 89052
H.L. Greenberg, M.D., LTD Withdrawn
Las Vegas, Nevada, United States, 89144
Robert Strimling and Associates LLC Active, not recruiting
Las Vegas, Nevada, United States, 89144
United States, New Hampshire
Dartmouth Hitchcock Medical Ctr - Dermatology Active, not recruiting
Lebanon, New Hampshire, United States, 03756
Nashua Dermatology Active, not recruiting
Nashua, New Hampshire, United States, 03062
United States, New Jersey
Belleville Dermatology Center PA Active, not recruiting
Belleville, New Jersey, United States, 07109
Windsor Dermatology, PC Active, not recruiting
East Windsor, New Jersey, United States, 08520
Hudson Dermatology & Skin Cancer Center Completed
Hoboken, New Jersey, United States, 07030
Aesthetic Dermatology Active, not recruiting
Marlton, New Jersey, United States, 08053
Heymann, Manders and Green, LLC Active, not recruiting
Marlton, New Jersey, United States, 08053
Dermatology & Dermatologic Surgery Completed
Rutherford, New Jersey, United States, 07070
Robert Wood Johnson Medical Center - Dermatology Active, not recruiting
Somerset, New Jersey, United States, 08873
The Dermatology Group, PC Active, not recruiting
Verona, New Jersey, United States, 07044
Linda Susan Marcus Dermatologist Active, not recruiting
Wyckoff, New Jersey, United States, 07481
United States, New York
Jeffrey LaDuca, MD, PC Active, not recruiting
Auburn, New York, United States, 13021
Albert Einstein College Of Medicine - Montefiore Medical Center Active, not recruiting
Bronx, New York, United States, 10467
Gary M. Hahn, M.D Completed
Commack, New York, United States, 11725
W & W Millenium Dermatology, PC Active, not recruiting
Elmhurst, New York, United States, 11373
Garden City Dermatology, P.C. Completed
Garden City, New York, United States, 11530
Mount Sinai North Shore Medical Group Completed
Huntington, New York, United States, 11743
Robert L. Bruckstein MDPC Completed
Lawrence, New York, United States, 11559
Mercer Street Medical Completed
New York, New York, United States, 10012
NYU School of Medicine Active, not recruiting
New York, New York, United States, 10016
Noah Scheinfeld, M.D., PLLC Active, not recruiting
New York, New York, United States, 10019
Icahn School of Medicine at Mount Sinai Completed
New York, New York, United States, 10029
South Nassau Communities Hospital Completed
Oceanside, New York, United States, 11572
Greene Richard M MD Active, not recruiting
Rochester, New York, United States, 00000
Dermatology Partners of Western New York, LLP Completed
Rochester, New York, United States, 14607
Genesee Valley Group Health Completed
Rochester, New York, United States, 14623
Thomas O McMeekin, MD P.C Completed
Rochester, New York, United States, 14623
Dermatique Dermatology Active, not recruiting
Smithtown, New York, United States, 11787
Dermatology Associates, Of New York Active, not recruiting
Staten Island, New York, United States, 10314
Derm Research Center of New York, Inc. Completed
Stony Brook, New York, United States, 11790
Joseph D. Sutton, M.D., PC Active, not recruiting
Suffern, New York, United States, 10901
Farah Dermatology Center Completed
Syracuse, New York, United States, 13210
Alan Schliftman MD, PC Dermatology Completed
White Plains, New York, United States, 10604
Buffalo Medical Group Active, not recruiting
Williamsville, New York, United States, 14221
United States, North Carolina
UNC at Chapel Hill, Clinical Research Unit Active, not recruiting
Chapel Hill, North Carolina, United States, 27516
George Fisher Withdrawn
Hickory, North Carolina, United States, 28601
PMG Research of Raleigh Completed
Raleigh, North Carolina, United States, 27609
Jeffrey M Suchniak Active, not recruiting
Rocky Mount, North Carolina, United States, 27804
Atlantic Dermatology Associates Completed
Wilmington, North Carolina, United States, 28401
Salem Medical Research Group Withdrawn
Winston-Salem, North Carolina, United States, 27103
United States, Ohio
Curtis W. Hawkins, MD Completed
Akron, Ohio, United States, 44313
Allied Dermatology and Skin Surgery Completed
Akron, Ohio, United States, 44333
Cincinnati Dermatology Center, LLC Completed
Cincinnati, Ohio, United States, 45236
Mid-Ohio Dermatology, Inc. Completed
Columbus, Ohio, United States, 43220
Wright State School of Medicine Completed
Dayton, Ohio, United States, 45408
Martha Ann Hickmann, M.D. Completed
Dayton, Ohio, United States, 45415
Timothy J. Storer, M.D. Completed
Delaware, Ohio, United States, 43015
Northeast Dermatology & Cosmetic Center Completed
Gahanna, Ohio, United States, 43230
The Ohio State University Medical Center Active, not recruiting
Gahanna, Ohio, United States, 43230
Frederick C. Smith Clinic Withdrawn
Marion, Ohio, United States, 43302
Brodell Medical Inc. Active, not recruiting
Warren, Ohio, United States, 44483
United States, Oklahoma
University of Oklahoma Board of Regents Completed
Oklahoma City, Oklahoma, United States, 73117
University of Oklahoma-Tulsa Completed
Oklahoma City, Oklahoma, United States, 73117
United States, Oregon
Park Avenue Dermatology Active, not recruiting
Coos Bay, Oregon, United States, 97420
Oregon Dermatology & Research Center Completed
Portland, Oregon, United States, 97210
Center for Dermatology and Laser Surgery Active, not recruiting
Portland, Oregon, United States, 97225
United States, Pennsylvania
Dermatology and Skin Surgery Center Active, not recruiting
Exton, Pennsylvania, United States, 19341
Andrew K. Pollack & Associates Completed
Fort Washington, Pennsylvania, United States, 19034
Paddington Testing Co, Inc. Completed
Philadelphia, Pennsylvania, United States, 19103
University of Pittsburgh Department of Dermatology Active, not recruiting
Pittsburgh, Pennsylvania, United States, 15213
Associates in Dermatology Withdrawn
Pittsburgh, Pennsylvania, United States, 15224
Vu Skin Research Withdrawn
Pittsburgh, Pennsylvania, United States, 15243
Dermatology Associates of Plymouth Meeting Active, not recruiting
Plymouth Meeting, Pennsylvania, United States, 19462
United States, South Carolina
Dermatology and Laser Center of Charleston Active, not recruiting
Charleston, South Carolina, United States, 29414
Fort Mill Dermatology LLC Completed
Fort Mill, South Carolina, United States, 29708
Advanced Dermatology and Laser Center Completed
Piedmont, South Carolina, United States, 29673
Westside Dermatology Active, not recruiting
Spartanburg, South Carolina, United States, 29306
United States, Tennessee
James Turner, MD, PHD, PC Completed
Bartlett, Tennessee, United States, 38134
East Tennessee Medical Research Completed
Bristol, Tennessee, United States, 37620
Lawrence H. Reid, MD, PC Withdrawn
Greeneville, Tennessee, United States, 37745
Dermatology Associates of Kingsport, PC Completed
Kingsport, Tennessee, United States, 37660
United States, Texas
Academy of Clinical Research LLC Completed
Arlington, Texas, United States, 76011
Arlington Center for Dermatology Active, not recruiting
Arlington, Texas, United States, 76011
Aftergut Dermatology Active, not recruiting
Cedar Hill, Texas, United States, 75104
Dermatology Treatment & Research Center, PA Active, not recruiting
Dallas, Texas, United States, 75230
Modern Research Associates PLLC Active, not recruiting
Dallas, Texas, United States, 75231
Baylor Research Institute - Dermatology Research Active, not recruiting
Dallas, Texas, United States, 75246
Heights Dermatology Active, not recruiting
Houston, Texas, United States, 77008
Baylor College Of Medicine - Dept Of Dermatology Withdrawn
Houston, Texas, United States, 77030
West Houston Dermatology PA Active, not recruiting
Houston, Texas, United States, 77082
Longview Dermatology Completed
Longview, Texas, United States, 75605
United States, Utah
University of Utah Active, not recruiting
Salt Lake City, Utah, United States, 84132
United States, Virginia
Glenn H. Fuchs, M.D., PC Completed
Arlington, Virginia, United States, 22204
Virginia Dermatology & Skin Cancer Center, Pllc Completed
Norfolk, Virginia, United States, 23502
Virginia Clinical Research Active, not recruiting
Norfolk, Virginia, United States, 23507
Skin & Laser Surgery Center Withdrawn
Vienna, Virginia, United States, 22182
Ken Tompkins Dermatology Withdrawn
Virginia Beach, Virginia, United States, 23454
United States, Washington
Island County Dermatology Withdrawn
Coupeville, Washington, United States, 98239
Center for Excellence in Dermatology, PLLC Active, not recruiting
Kennewick, Washington, United States, 99336
Skagit Valley Medical Center Completed
Mount Vernon, Washington, United States, 98274
Dermatology Associates of Seattle Active, not recruiting
Seattle, Washington, United States, 98101
Dr. James Hu Withdrawn
Seattle, Washington, United States, 98104
Allenmore Medical Center Completed
Tacoma, Washington, United States, 98405
Cascade Eye & Skin Center Completed
University Place, Washington, United States, 98467
Eastern Washington Dermatology Completed
Walla Walla, Washington, United States, 99362
United States, Wisconsin
Dermatology Associates of Wisconsin Completed
Green Bay, Wisconsin, United States, 54313
Great Lakes Dermatology, SC Completed
Pleasant Prairie, Wisconsin, United States, 53158
Shoreline Skin Specialists, S.C. Completed
Sheboygan, Wisconsin, United States, 53081
Hospital Italiano de Buenos Aires Active, not recruiting
Buenos Aires, Argentina, C1181ACH
Centro de Investigaciones Dermatologicas S.A. Withdrawn
Caba, Argentina, 1114
CEMIC Saavedra Withdrawn
Caba, Argentina
Lumipiel Active, not recruiting
Caba, Argentina
Fundación Medica de Cipoletti Completed
Cipoletti, Neuquén, Argentina
CEDIC Centro de Investigaciones Clinicas Active, not recruiting
Ciudad Autónoma de Buenos Aires, Argentina, C1425DES
Hospital San Martin de La Plata Withdrawn
La Plata, Argentina
Dermasur Active, not recruiting
Lomas de Zamora, Argentina
Centro Dermatologico Schejtman Active, not recruiting
San Miguel, Argentina
Fremantle Dermatology Recruiting
Fremantle, Australia, 6160
Skin&Cancer Foundation Inc Recruiting
Melbourne, Australia, 3053
Kingsway Dermatology & Aesthetics Recruiting
Miranda, Australia, 2228
Westmead Hospital Not yet recruiting
Sydney, Australia, 2145
Veracity Clinical Research Not yet recruiting
Woolloongabba, Australia, 4102
LKH Feldkirch Completed
Feldkirch N/a, Austria, 6807
Praxis Gassner Active, not recruiting
Klagenfurt, Austria, 9020
Praxis Popp-Habeler Active, not recruiting
Laakirchen, Austria, 4663
Allg. Krankenhaus der Landeshauptstadt St. Poelten Active, not recruiting
St Poelten, Austria, 3100
Allgemeines Krankenhaus der Stadt Wien Active, not recruiting
Wien, Austria, 1090
AZ Sint-Jan Brugge-Oostende AV Recruiting
Brugge, Belgium, 8000
UCL Hopital Saint-Luc Recruiting
Bruxelles, Belgium, 1200
Universitair Ziekenhuis - Antwerpen Active, not recruiting
Edegem, Belgium, B-2650
Universitair Ziekenhuis Gent - UZ GENT Recruiting
Gent, Belgium, 9000
UZ Leuven Recruiting
Leuven, Belgium, 3000
CHU de Liège - Domaine Universitaire du Sart Tilman Active, not recruiting
Liege, Belgium, 4000
Grand Hôpital de Charleroi Not yet recruiting
Loverval, Belgium, 6280
Ghislain Dermatologie SC SPRL Recruiting
Mons, Belgium, 7000
Canada, Alberta
Kirk Barber Research Completed
Calgary, Alberta, Canada, T2G1B1
Institute for Skin Advancement Not yet recruiting
Calgary, Alberta, Canada, T3A 2N1
Stratica Medical Recruiting
Edmonton, Alberta, Canada, T5K 1X3
University of Alberta Not yet recruiting
Edmonton, Alberta, Canada, T6G 2G3
Canada, British Columbia
Wellington Medical Clinic Recruiting
Nanaimo, British Columbia, Canada, V9T 1W1
Dr. Chih-ho Hong Medical Inc. Recruiting
Surrey, British Columbia, Canada, V3R 6A7
Enverus Medical Completed
Surrey, British Columbia, Canada, V3V 0C6
Derm Research @ 888 Inc. Completed
Vancouver, British Columbia, Canada, V5Z 3Y1
University of British Columbia Recruiting
Vancouver, British Columbia, Canada, V5Z 4E8
Canada, Manitoba
Winnipeg Clinic Recruiting
Winnipeg, Manitoba, Canada, R3C 0N2
Dermadvances Research Completed
Winnipeg, Manitoba, Canada, R3C 1R4
Wiseman Dermatology Research Inc. Not yet recruiting
Winnipeg, Manitoba, Canada, R3M 3Z4
Canada, New Brunswick
Brunswick Dermatology Center Not yet recruiting
Fredrickton, New Brunswick, Canada, E3B 1G9
Durondel C. P. Inc. Active, not recruiting
Moncton, New Brunswick, Canada, E1C 8X3
Canada, Newfoundland and Labrador
Karma Clinical Trials Inc. Recruiting
St. John's, Newfoundland and Labrador, Canada, A1A 4Y3
Nexus Clinical Research Recruiting
St. John's, Newfoundland and Labrador, Canada, A1A 5E8
New Lab Clinical Research Inc. Recruiting
St. John's, Newfoundland and Labrador, Canada, A1C 2H5
Canada, Nova Scotia
Eastern Canada Cutaneous Research Associates Recruiting
Halifax, Nova Scotia, Canada, B3H 1Z2
Dr. Scott J. Murray Inc. Recruiting
Halifax, Nova Scotia, Canada, B3K 5R3
Michael Shaffelburg M.D. Recruiting
Kentville, Nova Scotia, Canada, B4N 4K9
Canada, Ontario
The Waterside Clinic Active, not recruiting
Barrie, Ontario, Canada, L4M 6L2
Dermatrials Research Active, not recruiting
Hamilton, Ontario, Canada, L8N 1Y2
Ruth MacSween M.D. Recruiting
Kingston, Ontario, Canada, K7L 1S2
K. Papp Clinical Research Inc. Recruiting
Kitchener, Ontario, Canada, N2J 1C4
Mediprobe Research Inc. Completed
London, Ontario, Canada, N5X 2P1
The Guenther Dermatology Research Centre Recruiting
London, Ontario, Canada, N6A 3H7
Lynderm Research Inc. Recruiting
Markham, Ontario, Canada, L3P 1X2
Dr. Sk Siddha Medicine Professional Corporation Not yet recruiting
Newmarket, Ontario, Canada, L3Y5G8
North Bay Dermatology Centre Active, not recruiting
North Bay, Ontario, Canada, P1B 3Z7
JRB Research Inc Not yet recruiting
Ottawa, Ontario, Canada, K1H 7X3
Bruyère Research Institute Recruiting
Ottawa, Ontario, Canada, K1N 5C8
Dermatology Ottawa Research Centre Recruiting
Ottawa, Ontario, Canada, K2C 3N2
Skin Centre for Dermatology Recruiting
Peterborough, Ontario, Canada, K9J 5K2
Specilaized Dermatology Completed
St Catherines, Ontario, Canada, L2R 5W4
Sudbury Skin Clinique Recruiting
Sudbury, Ontario, Canada, P3C 1X8
AvantDerm Not yet recruiting
Toronto, Ontario, Canada, M5A 3R6
Manna Research Active, not recruiting
Toronto, Ontario, Canada, M9W 4L6
XLR8 Medical Research Completed
Windsor, Ontario, Canada, N8W 1E6
Windsor Clinical Research Active, not recruiting
Windsor, Ontario, Canada, N8W 5L7
Canada, Quebec
Isabelle Delorme Inc. Active, not recruiting
Drummondville, Quebec, Canada, J2B 5L4
Innovaderm Research Inc. Recruiting
Montreal, Quebec, Canada, H2K 4L5
Sienna Medical Corporation Recruiting
Montreal, Quebec, Canada, H3Z 2S6
CHAUQ- Hopital du St-Sacrement Active, not recruiting
Quebec, Canada, G1S 4L8
Centre De Recherche Dermatologique Du Quebec Metropolitan Recruiting
Quebec, Canada, G1V 4X7
Centro Medico Skin-Med Active, not recruiting
Santiago - Las Condes, Chile, 7580206
Centro Médico San Joaquín Completed
Santiago - Macul, Chile
Centro Dermatologico Universitario Completed
Santiago, Chile
Centro Internacional de Estudios Clinicos Active, not recruiting
Santiago, Chile
Fundacion Para La Investigacion En Dermatologia Funinderma Active, not recruiting
Bogota, Colombia
Fundación Centro de Investigación CIC Active, not recruiting
Medellin, Colombia
Instituto De Coloproctologia Ico S.A.S Active, not recruiting
Medellin, Colombia
Fakultni nemocnice u sv. Anny v Brne Completed
Brno, Czechia, 65691
Nemocnice Ceske Budejovice, a.s. Active, not recruiting
Ceske Budejovice, Czechia, 37087
Nemocnice Jihlava Active, not recruiting
Jihlava N/a, Czechia, 586 33
FN Olomouc Not yet recruiting
Olomouc, Czechia, 779 00
Vojenska nemocnice Olomouc Active, not recruiting
Olomouc, Czechia, 77900
Pardubicka krajska nemocnice a.s. Not yet recruiting
Pardubice, Czechia, 532 03
FN Plzen Not yet recruiting
Plzen, Czechia, 305 99
Fakultni nemocnice Kralovske Vinohrady Active, not recruiting
Praha 10, Czechia, 100 34
Vseobecna Fakultní Nemocnice Active, not recruiting
Praha 2, Czechia, 128 08
FN Motol Not yet recruiting
Praha 5, Czechia, 150 06
Nemocnice Na Bulovce Active, not recruiting
Praha 8, Czechia, 180 81
Masarykova nemocnice v Usti nad Labem Active, not recruiting
Usti nad Labem, Czechia, 40113
401 Army General Hospital Not yet recruiting
Athens, Greece, 11526
Attikon Hospital Active, not recruiting
Athens, Greece, 12462
Andreas Sygros Hospital Active, not recruiting
Athens, Greece, 16121
University Hospital of Heraklion Completed
Heraklion, Greece, 711 10
Ioannina University Hospital Active, not recruiting
Ioannina, Greece, 45 500
University Hospital Of Larisa Active, not recruiting
Larisa, Greece, 411 10
University General Hospital of Rio Patras Not yet recruiting
Patras, Greece, 25100
Tzaneio Hospital Not yet recruiting
Piraeus-Athens, Greece, 16132
University Hospital for Skin and Venereal Diseases Active, not recruiting
Thessaloniki, Greece, 54 643
Hospital of Skin and Veneral Diseases Not yet recruiting
Thessaloniki, Greece, 54643
Papageorgiou General Hospital Not yet recruiting
Thessaloniki, Greece, 56403
Haemek Recruiting
Afula, Israel
Clalit Health Services - Sald Specialist Center Active, not recruiting
Beer Sheva, Israel, 84894
Clalit Health Services - Armon Dermatology Clinic Completed
Haifa, Israel, 33501
Clalit Health Services- Netivot Clinic Completed
Netivot, Israel, 87733
Rabin Medical Center Not yet recruiting
Petach Tikva, Israel, 4941492
Sheba Medical Center Not yet recruiting
Ramat Gan, Israel, 52621
Clalit Health Care Services - Tel Nordau Clinic Completed
Tel Aviv, Israel, 63564
AOU di Cagliari Recruiting
Cagliari, Italy, 09124
P.O. Vittorio Emanuele Azienda Ospedaliero Universitaria 'Policlinico Vittorio Emanuele' Recruiting
Catania, Italy, 95123
IRCCS Aor San Martino IST Recruiting
Genova, Italy, 16132
Ospedale San Salvatore Recruiting
L'Aquila, Italy, 67100
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Recruiting
Milano, Italy, 20122
Azienda Ospedaliera Universitaria Federico II Recruiting
Napoli, Italy, 80131
University of Campania - Nuovo Policlinico Recruiting
Napoli, Italy, 80131
Azienda Ospedaliera Universitaria 'Policlinico Tor Vergata' Recruiting
Roma, Italy, 00133
Policlinico Universitario Agostino Gemelli Recruiting
Roma, Italy, 00168
Istituto Clinico Humanitas Recruiting
Rozzano, Italy, 20089
Ospedale Alfredo Fiorini Recruiting
Terracina, Italy, 04019
Ospedale San Bortolo Recruiting
Vicenza, Italy, 36100
Korea, Republic of
Korea University Ansan Hospital Not yet recruiting
Ansan-si, Korea, Republic of, 15355
Pusan National University Hospital Not yet recruiting
Busan, Korea, Republic of, 46241
Seoul National University Bundang Hospital Recruiting
Seongnam-si, Korea, Republic of, 13620
Severance Hospital, Yonsei University Health System Not yet recruiting
Seoul, Korea, Republic of, 03722
Konkuk University Medical Center Recruiting
Seoul, Korea, Republic of, 143-729
CHA Bundang Medical center, CHA University Not yet recruiting
Sungnam, Korea, Republic of, 13496
Consultorio Privado Active, not recruiting
Estado de Mexico, Mexico
Consultorio Privado Dra. Leon Completed
Mexico city, Mexico, 06760
Private Practice Dr Amaya Active, not recruiting
Monterrey, Mexico, 64060
Instituto Dermatologico de Jalisco Active, not recruiting
Zapopan, Mexico, 45190
Centrum Oosterwal Recruiting
Alkmaar, Netherlands, 1817 MS
AMC Recruiting
Amsterdam Zuidoost, Netherlands, 1105 AZ
Amphia Ziekenhuis, locatie Molengracht - Afd. Longziekten Active, not recruiting
Breda, Netherlands, 4818 CK
Deventer Ziekenhuis Active, not recruiting
Deventer, Netherlands, 7416 SE
Elkerliek Zkhs,Lok.Helmond - Afd.Dermatologie - DER Terminated
Helmond, Netherlands, 5707 HA
UMC,Lok.Sint Radboud - Afd.Dermatologie 802 - DER Recruiting
Nijmegen, Netherlands, 6525GL
Centro Clinico Académico de Braga Not yet recruiting
Braga, Portugal, 4710-243
Clínica Dr. Artur Sousa Basto Active, not recruiting
Braga, Portugal, 4715-012
Hospital Santo Antonio dos Capuchos Not yet recruiting
Lisboa, Portugal, 1169-050
Clinica Laser De Belem Active, not recruiting
Lisboa, Portugal, 1300015
Hospital De Santa Maria Completed
Lisboa, Portugal, 1649035
Hospital Cuf Descobertas Active, not recruiting
Lisboa, Portugal, 1998050
Hospital De Santa Maria Not yet recruiting
Lisbon, Portugal, 1649-035
Hospital Geral de Santo Antonio Active, not recruiting
Porto, Portugal, 4099-001
Centro Hospitalar Vila Nova de Gaia Not yet recruiting
Vila Nova de Gaia, Portugal, 4400-129
Dermatovenerologicke oddelenie, FNsP F. D. Roosevelta Banska Bystrica Active, not recruiting
Banska Bystrica, Slovakia, 975 17
I. Dermatovenerologicka klinika LFUK a FNsP Bratislava, Nemocnica Stare mesto Active, not recruiting
Bratislava, Slovakia, 813 69
Pedi-Derma s.r.o. Active, not recruiting
Kosice, Slovakia, 040 11
Univerzitná nemocnica Martin Active, not recruiting
Martin, Slovakia, 03601
Kozne oddelenie, Nemocnica Poprad Active, not recruiting
Poprad, Slovakia, 058 45
Oddelenie dermatovenerológie FNsP J. A. Reimana Prešov Active, not recruiting
Presov, Slovakia, 080 01
Kozne oddelenie FN Trnava Active, not recruiting
Trnava, Slovakia, 917 75
Splosna bolnisnica Celje, Dermatoveneroloski oddelek Active, not recruiting
Celje, Slovenia, 3000
Marko Vok Dermatoveneroloska ambulanta Active, not recruiting
Izola, Slovenia, 6310
Dermatovenerologija, dermatološka zasebna ordinacija, Natalija Evdakova Bodiroža s.p. Active, not recruiting
Kranj, Slovenia, 4000
AKD d.o.o. Completed
Ljubljana, Slovenia, 1000
Dermadent d.o.o. Withdrawn
Ljubljana, Slovenia, 1000
Dermatologija Bartenjev Rogl Withdrawn
Ljubljana, Slovenia, 1000
Dermatoloski center Derm. Completed
Ljubljana, Slovenia, 1000
Univerzitetni klinicni center Ljubljana, Dermatovenerološka klinika Active, not recruiting
Ljubljana, Slovenia, 1000
UKC Maribor Dermatology clinic Active, not recruiting
Maribor, Slovenia, 2000
Medical Center Rogaska Withdrawn
Rogaska Slatina, Slovenia, 3250
Hosp. Univ. Principe de Asturias Not yet recruiting
Alcalá de Henares, Spain, 28805
Hosp. Univ. de Basurto Not yet recruiting
Bilbao, Spain, 48013
Hosp. Univ. San Cecilio Not yet recruiting
Granada, Spain, 18016
Hosp. Univ. Lucus Augusti Withdrawn
Lugo, Spain, 27003
Hosp. Univ. de Torrejon Not yet recruiting
Madrid, Spain, 28850
Hosp. Univ. Fuenlabrada Not yet recruiting
Madrid, Spain, 28942
Hosp. Gral. Univ. J.M. Morales Meseguer Not yet recruiting
Murcia, Spain, 30008
Hosp. Clinico Univ. de Salamanca Not yet recruiting
Salamanca, Spain, 37007
Hosp. Clinico Univ. de Santiago Not yet recruiting
Santiago de Compostela, Spain, 15706
Hosp. de Manises Withdrawn
Valencia, Spain, 46940
Mälarsjukhuset Eskilstuna Recruiting
Eskilstuna, Sweden, 631 88
Sahlgrenska University Hospital Recruiting
Goteborg, Sweden, 41346
Hallandskustens Hudmottagning Recruiting
Kungsbacka, Sweden, 43432
Psoriasisforeningens behandlingsmottagningar Recruiting
Stockholm, Sweden, 11856
Chang Gung Memorial Hospital Not yet recruiting
Kaohsiung, Taiwan, 83301
Taichung Veterans General Hospital Not yet recruiting
Taichung, Taiwan, 407
Chang Gung Memorial Hospital Taipei Not yet recruiting
Taipei-City, Taiwan, 105
National Taiwan University Hospital Not yet recruiting
Taipei, Taiwan, 10002
Chang Gung Memorial Hospital- Linkou Not yet recruiting
Taoyuan County, Taiwan, 33305
Dnepropetrovsk State Med Academy, Dermatovenerology Dep, City Clin Hosp # 17, Dermatovenerology Dep Completed
Dnepropetrovsk, Ukraine, 49074
Donetsk National Medical University, Dep of Dermatovenerology and Cosmetology Completed
Donetsk, Ukraine, 83097
Kharkiv City Dermatovenerological Dispensary #4 Active, not recruiting
Kharkiv, Ukraine, 61012
Khmelnitskiy Regional Dermatovenerological Dispensary, Dep of Dermatology Completed
Khmelnitskiy, Ukraine, 29000
Institute of Psoriasis and Chronic Dermatoses, Dep of Dermatology Completed
Kiev, Ukraine, 04107
Lugansk Regional Dermatovenerological Dispensary, Dep of Dermatology Completed
Lugansk, Ukraine, 91047
Crimean Med University, Dep of Dermatovenerology, CRE "Clinical Dermatovenerological Dispensary" Completed
Simferopol, Ukraine
Uzhgorod National University, Department of Dermatovenerology Active, not recruiting
Uzhgorod, Ukraine, 88011
Sponsors and Collaborators
Janssen Scientific Affairs, LLC
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Study Director: Janssen Scientific Affairs, LLC Clinical Trial Janssen Scientific Affairs, LLC

Additional Information:
Publications automatically indexed to this study by Identifier (NCT Number):

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Responsible Party: Janssen Scientific Affairs, LLC Identifier: NCT00508547     History of Changes
Other Study ID Numbers: CR013225
PSOLAR ( Other Identifier: Janssen Scientific Affairs, LLC )
First Posted: July 30, 2007    Key Record Dates
Last Update Posted: November 1, 2019
Last Verified: October 2019

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Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Janssen Scientific Affairs, LLC:
Systemic PUVA
Psoriatic arthritis
Skin disease
Additional relevant MeSH terms:
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Arthritis, Psoriatic
Joint Diseases
Musculoskeletal Diseases
Skin Diseases, Papulosquamous
Skin Diseases
Spinal Diseases
Bone Diseases
Antibodies, Monoclonal
Dermatologic Agents
Gastrointestinal Agents
Antirheumatic Agents
Immunologic Factors
Physiological Effects of Drugs