Danish Lung Cancer Screening Trial (DLCST) (DLCST)
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|ClinicalTrials.gov Identifier: NCT00496977|
Recruitment Status : Unknown
Verified June 2007 by Danish Lung Cancer Group.
Recruitment status was: Active, not recruiting
First Posted : July 6, 2007
Last Update Posted : July 6, 2007
|Condition or disease||Intervention/treatment||Phase|
|Lung Cancer||Procedure: annual CT screening||Not Applicable|
The trial is a parallel randomized controlled trial comparing either a yearly low dose CT scan or no screening. It is scheduled to enroll 4000 smokers and former smokers, and the study is scheduled to last 5 years, i.e. an initial (prevalence) screening is followed by 4 annual (incidence) screenings.
In addition the following investigations are done: A prospective, longitudinal questionnaire assessment of enrolled participants who have received a false positive diagnosis. The questionnaire will focus on the consequences of receiving a false positive diagnosis. Answers from enrolled subjects who have received a false positive diagnosis will be compared to their own "baseline" responses, and responses from subjects who have received a negative result of their own low-dose CT scans All participants will annually be questioned regarding smoking habits, their motivation for cessation of smoking and will be advised to refrain from smoking to assess the effect of participation in a screening protocol for lung cancer on cessation of smoking.
Socioeconomic consequences of screening for lung cancer will be assessed by longitudinal registration of costs and benefits (e.g. morbidity, hospitalization, GP consultations etc.
Assess the value of PET scanning when screening for lung cancer.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||4104 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Screening for Lung Cancer. A Randomised Controlled Trial of Low-Dose CT-Scanning.|
|Study Start Date :||October 2004|
|Estimated Study Completion Date :||January 2010|
- Lung cancer mortality [ Time Frame: 10 years ]
- lung cancer incidense and stagedistribution [ Time Frame: 5 years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00496977
|Lung Screening Clinic, Gentofte University Hospital|
|Hellerup, Denmark, DK-2900|
|Principal Investigator:||Jesper H Pedersen, MD, Dr.Sci||Gentofte University Hospital, Hellerup, Denmark|