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Investigation of Genetic Risk of Atrial Fibrillation

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2006 by Nagoya University.
Recruitment status was:  Recruiting
Information provided by:
Nagoya University Identifier:
First received: December 15, 2006
Last updated: NA
Last verified: December 2006
History: No changes posted
The atrial fibrillation (AF) is the most common cardiac rhythm disturbance that is responsible for substantial morbidity and mortality independent of associated heart disease or other risk factors. Even in the absence of preexisting cardiovascular disease, AF remains significantly associated with excess mortality rates. The current unsatisfactory treatment for AF comes from lack of understanding of the pathophysiology of AF. The purpose of this study is to identify gene polymorphisms that confer susceptibility to atrial fibrillation. Patients with AF(N=500) and healthy volunteer(N=1000) without AF are enrolled in this study. Patients with coronary artery disease, severe valvular heart disease, cardiomyopathy or heart failure were excluded from the study.

Atrial Fibrillation

Study Type: Observational
Study Design: Observational Model: Case Control
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Official Title: Investigation of Genetic Risk of Atrial Fibrillation

Resource links provided by NLM:

Further study details as provided by Nagoya University:

Estimated Enrollment: 1000
Study Start Date: October 2006

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Clinical diagnosis of atrial fibirillation

Exclusion Criteria:

  • coronary artery disease
  • severe valvular heart disease
  • cardiomyopathy
  • heart failure
  Contacts and Locations
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Please refer to this study by its identifier: NCT00412438

Contact: Kenji Yasui, MD, PhD +81-52-788-6211
Contact: Masaki Yamauchi, MD +81-52-788-6210

Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University Recruiting
Nagoya, Aichi, Japan
Contact: Kenji Yasui, MD, PhD    +81-52-6211   
Contact: Masaki Yamauchi, MD    +81-52-6211   
Sponsors and Collaborators
Nagoya University
Study Chair: Kenji Yasui, MD, Phd Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University
  More Information Identifier: NCT00412438     History of Changes
Other Study ID Numbers: RIEM-G-1
Study First Received: December 15, 2006
Last Updated: December 15, 2006

Keywords provided by Nagoya University:
Atrial Fibrillation

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes processed this record on May 25, 2017