Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.
|ClinicalTrials.gov Identifier: NCT00200928|
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : April 4, 2006
|Condition or disease||Intervention/treatment|
|Food Allergy Atopic Dermatitis Asthma Rhinitis||Biological: BCG|
A randomised single blinded intervention study in high-risk newborns vaccinated at the age of 6 weeks with BCG or placebo.
Inclusion: high-risk was defined as either a mother or a father and a sibling with present or past atopic disease.
Exclusion: maternal infection in the last week of pregnancy, the use of immunomodulatory drugs or antibiotics during pregnancy (mother), the use of antibiotics directly post-partum (newborn)
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||120 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.|
|Study Start Date :||January 1999|
|Estimated Study Completion Date :||July 2005|
- Incidence and severity of atopic disease.
- SCORAD, lung function, IgE, cytokine production by PBMNC's, NRAMP-polymorphisms.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00200928
|Wilhelmina Children's Hospital (UMCU)|
|Utrecht, Netherlands, 3508AB|
|Principal Investigator:||Maarten O Hoekstra, MD PhD||Wilhelmina Children's Hospital Utrecht (UMCU)|