ClinicalTrials.gov
ClinicalTrials.gov Menu

Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00178061
Recruitment Status : Completed
First Posted : September 15, 2005
Last Update Posted : June 25, 2013
Sponsor:
Information provided by:
University of Pittsburgh

Brief Summary:
This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

Condition or disease Intervention/treatment Phase
Bipolar I Disorder Borderline Personality Disorder Behavioral: Interpersonal Social Rhythm Therapy (IPSRT) Phase 4

Detailed Description:

The major aim of this proposal is to examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

The specific aims are to create a research and supervisory team and to identify potential moderators of treatment response and mediators of outcome over the course of treatment.

Members of the team will meet weekly to begin a treatment development process for enhancing Interpersonal Social Rhythm Therapy (IPSRT) for these patients. Additional assessment measures will be utilized to examine the proposed mediators and moderators of treatment.


Study Type : Interventional  (Clinical Trial)
Enrollment : 13 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Treatment of Primary Mood Disorders in the Comorbidly Ill
Study Start Date : August 1997
Study Completion Date : August 2002

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Hamilton Rating Scale for Depression (HRSD-25)

Secondary Outcome Measures :
  1. Raskin Severity of Depression and Mania Scales


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Bipolar I Disorder with Comorbid Borderline Personality Disorder, currently manic or depressed

Exclusion Criteria:

  • Unstable Medical illness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00178061


Locations
United States, Pennsylvania
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: Ellen Frank University of Pittsburgh

ClinicalTrials.gov Identifier: NCT00178061     History of Changes
Other Study ID Numbers: 970843-0109
970843-0109
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: June 25, 2013
Last Verified: June 2013

Additional relevant MeSH terms:
Disease
Personality Disorders
Borderline Personality Disorder
Pathologic Processes
Mental Disorders