Honolulu Heart Program

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: September 2004

To investigate coronary heart disease and stroke among American men of Japanese ancestry who were living on the island of Oahu in 1965. Morbidity and mortality surveillance of the original cohort is continuing.

Cardiovascular Diseases
Coronary Disease
Cerebrovascular Accident
Heart Diseases
Heart Failure, Congestive
Myocardial Infarction
Lung Diseases, Obstructive
Aortic Aneurysm, Abdominal
Chronic Obstructive Pulmonary Disease
Heart Failure

Study Type: Observational

Resource links provided by NLM:

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: July 1965
Estimated Study Completion Date: September 2002
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Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No

No eligibility criteria

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00005123

Sponsors and Collaborators
Investigator: J. Curb Kuakini Medical Center
Investigator: Jess Curb Kuakini Medical Center
  More Information

McGee D, Rhoads G, Feinleib M: The Logistic Function. A Model for Assessing Risk of Heart Disease. In Proceedings of the Fourteenth Hawaii International Conference on System Sciences. Edited by B. Shriver et al. Honolulu, Hawaii, University of Hawaii Press pp 722-740, 1981
Kagan A, Yano K, McGee D, Rhoads GG: Epidemiology of Glucose Intolerance in Hawaii Japanese Men. Excerpta Medica. In: Genetic-Enviornmental Interaction in Diabetes Mellitus, Proceedings of the Third Symposium on Diabetes Mellitus in Asia and Oceania; Honolulu Feb 6-7, 1981; ISBN Elsevier North Holland, (International Congress Series No. 549, pp 51-56, 1982
Reed D: Social Stress, Social Support and Hypertension Among Japanese Men in Hawaii. In Proceedings of the Second Intercontinental Symposium on Hypertension and the Japanese. Molokai, Hawaii. Japan, Medical Tribune, pp 21-30, 1983
Reed DM: Predictors of a Long Healthy Life Among Japanese Men in Hawaii. In: Prevention of Cardiovascular Diseases: an Approach to Active Long Life. Yamori Y, Lenfant C (Eds). Elsevier Science Publishers, pp 225-234, 1987
Rhoads GG, Zeegen PD, Glober GA, Boelling GM: The Epidemiology of Pterygium a High Risk Population. Transactions of Pacific Coast Oto-Ophthalmological Society pp 163-173, 1972
Kagan A: The World Wide Investigation of the Epidemiology of Coronary Heart Disease. J Hiroshima Med Assoc 26:10:1145-1157, 1973
Rhoads GG, Kagan A, Yano K: Usefulness of Community Surveillance for the Ascertainment of Coronary Heart Disease and Stroke. Int J Epidemiol 4:4:265-270, 1975
Kagan A, Gordon T, Rhoads GG, Schiffman JC: Some Factors Related to Coronary Heart Disease Incidence in Honolulu Japanese Men. The Honolulu Heart Study. Int J Epidemiol 4:4:271-279, 1975
Winkelstein W Jr: Cooperative Studies of Blood Pressure in Japanese in Japan, Hawaii and the United States. In Epidemiology and Control of Hypertension Paul O (Ed.) Miami: Symposia Specialists, pp 101-114, 1975
Kagan A: Epidemiology of Hypertension and Stroke in Oceania. In Hypertension and Stroke Control in the Community Hatano S, Shigematsu I, Strasser T (Eds.) Geneva: World Health Organization, pp 97-105, 1976
Kagan A, Popper J, Rhoads GG, Takeya Y, Kato H, Brown-Goode G, Marmot MG: Epidemiologic Studies of Coronary Heart Disease and Stroke in Japanese Men Living in Japan, Hawaii, and California: Prevalence of Stroke. In Cerebrovascular Diseases, Tenth Princeton Conference Scheinberg P (Ed.) New York: Raven Press, pp 267-277, 1976
Takeya Y, Kato H, Kagan A, Popper J, Rhoads GG, Browne Goode G, Marmot M: Epidemiologic Study of Stroke in Japanese Men Living in Japan, Hawaii and California: Prevalence of Stroke. In Gene-Environment Interaction in Common Diseases Inouye E, Nishimura H (Eds.) University of Tokyo Press, pp 15-18, 1977
Kagan A, Marmot MG, Kato H: The Ni-Hon-San Study of Cardiovascular Disease Epidemiology: Population Characteristics and Epidemiology of Stroke. In Epidemiology of Arterial Blood Pressure. Kesteloot H, Joossens JV (Eds.). The Hague/Boston/London: Martinus Nijhoff, pp 423-436, 1980, 0000
Marmot MG, Kagan A, Kato H: Hypertension and Heart Disease in the Ni-Hon-San Study. In Epidemiology of Arterial Blood Pressure. Kesteloot H, Joossens JV (Eds.). The Hague/Boston/London: Martinus Nijhoff, pp 437-452, 1980

ClinicalTrials.gov Identifier: NCT00005123     History of Changes
Other Study ID Numbers: 902
Study First Received: May 25, 2000
Last Updated: June 23, 2005
Health Authority: Unspecified

Additional relevant MeSH terms:
Aortic Aneurysm, Abdominal
Cerebral Infarction
Heart Failure
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Aortic Aneurysm
Aortic Diseases
Brain Diseases
Brain Infarction
Brain Ischemia
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Heart Diseases
Lung Diseases
Nervous System Diseases
Respiratory Tract Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on March 26, 2015