A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
This study has been completed.
Information provided by:
NIH AIDS Clinical Trials Information Service
First received: November 2, 1999
Last updated: June 23, 2005
Last verified: April 1996
To determine the safety and efficacy of oral valacyclovir hydrochloride ( 256U87 ) compared to acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients with CD4 counts = or > 100 cells/mm3.
Drug: Valacyclovir hydrochloride
||Endpoint Classification: Safety Study
Primary Purpose: Treatment
||A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
|Ages Eligible for Study:
||18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Patients must have:
- HIV infection with CD4 counts = or > 100 cells/mm3.
- Documented culture of anogenital herpes simplex virus (HSV) within the last 5 years.
- History of recurrent anogenital HSV infection, with a recurrence (with or without culture) within 1 year prior to study.
Patients with the following symptoms and conditions are excluded:
- Malabsorption or vomiting that would potentially limit the retention and absorption of oral therapy.
- Systemic antiherpes medication.
Patients with the following prior conditions are excluded:
History of hypersensitivity to acyclovir.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00002084
No publications provided
History of Changes
|Other Study ID Numbers:
|Study First Received:
||November 2, 1999
||June 23, 2005
||United States: Food and Drug Administration
Keywords provided by NIH AIDS Clinical Trials Information Service:
Acquired Immunodeficiency Syndrome
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on February 27, 2015