Evaluation of the Genetics of Bipolar Disorder
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|ClinicalTrials.gov Identifier: NCT00001174|
Recruitment Status : Recruiting
First Posted : November 4, 1999
Last Update Posted : October 26, 2021
|Condition or disease|
Bipolar affective disorder is a severe, heritable condition affecting about one percent of
the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute to the risk of bipolar disorder. Individuals diagnosed with bipolar disorder are studied, along with their relatives. Phenotypic information obtained from clinical interviews and family history is correlated with genotypic information obtained from genetic marker and sequencing methods. The goal is to identify genes involved in bipolar disorder and related conditions so that better methods of diagnosis, treatment, and prevention can be developed.
|Study Type :||Observational|
|Estimated Enrollment :||4000 participants|
|Official Title:||Bipolar Genetics: A Collaborative Study|
|Actual Study Start Date :||August 11, 1994|
Patients with bipolar disorder
- To ascertain individuals with bipolar disorder and at least one affected relative and to conduct direct diagnostic interviews and collect blood samples for testing, lymphoblastoid cell lines and/or extraction of DNA. [ Time Frame: ongoing ]To ascertain individuals with bipolar disorder and at least one affected relative and to conduct direct diagnostic interviews and collect blood samples for testing, lymphoblastoid cell lines and/or extraction of DNA.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001174
|Contact: Emily Besancon||(866) firstname.lastname@example.org|
|Contact: Francis J McMahon, M.D.||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
|Principal Investigator:||Francis J McMahon, M.D.||National Institute of Mental Health (NIMH)|