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IV Cocaine Abuse: A Laboratory Model - 2

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00000213
Recruitment Status : Completed
First Posted : September 21, 1999
Last Update Posted : August 28, 2015
Sponsor:
Collaborators:
National Institute on Drug Abuse (NIDA)
Columbia University
Information provided by (Responsible Party):
New York State Psychiatric Institute

Study Description
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Brief Summary:
The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Condition or disease Intervention/treatment Phase
Cocaine-Related Disorders Drug: Fluoxetine Phase 2

Study Design
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Study Type : Interventional  (Clinical Trial)
Enrollment : 0 participants
Primary Purpose: Treatment
Official Title: IV Cocaine Abuse: A Laboratory Model
Study Start Date : April 1990
Actual Primary Completion Date : April 1991
Actual Study Completion Date : April 1991

Resource links provided by the National Library of Medicine

Drug Information available for: Fluoxetine

Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. Direct cocaine effects
  2. Interaction of cocaine/fluox. on cardio measures
  3. Interaction of cocaine/fluox. on coc's subjective
  4. Effects of fluoxetine on cocaine craving
  5. Drug use during outpatient fluoxetine maintenance

Eligibility Criteria
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Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
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Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000213


Locations
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United States, New York
Columbia University
New York, New York, United States, 10023
Sponsors and Collaborators
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)
Columbia University
Investigators
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Principal Investigator: Richard Foltin, Ph.D. Columbia University
More Information
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Responsible Party: New York State Psychiatric Institute
ClinicalTrials.gov Identifier: NCT00000213    
Other Study ID Numbers: NIDA-06234-2
R01DA006234 ( U.S. NIH Grant/Contract )
R01-06234-2
First Posted: September 21, 1999    Key Record Dates
Last Update Posted: August 28, 2015
Last Verified: December 2012
Keywords provided by New York State Psychiatric Institute:
intravenous abuse
Additional relevant MeSH terms:
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Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Fluoxetine
Selective Serotonin Reuptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
 Neurotransmitter Agents
Serotonin Agents
Physiological Effects of Drugs
Antidepressive Agents, Second-Generation
Antidepressive Agents
Psychotropic Drugs
Cytochrome P-450 CYP2D6 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Enzyme Inhibitors