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Trial record 38 of 232 for:    EDN1

The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls

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ClinicalTrials.gov Identifier: NCT03534427
Recruitment Status : Completed
First Posted : May 23, 2018
Results First Posted : August 14, 2019
Last Update Posted : August 14, 2019
Sponsor:
Information provided by (Responsible Party):
Songyoung Park, Pusan National University

Study Type Interventional
Study Design Allocation: Randomized;   Intervention Model: Parallel Assignment;   Masking: None (Open Label);   Primary Purpose: Health Services Research
Conditions Prehypertension
Blood Pressure
Abdominal Obesity
Adiposity
Intervention Other: Jump rope exercise intervention
Enrollment 40
Recruitment Details  
Pre-assignment Details  
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Period Title: Overall Study
Started 20 20
Completed 20 20
Not Completed 0 0
Arm/Group Title Control Group Jump Rope Exercise Intervention Total
Hide Arm/Group Description No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Total of all reporting groups
Overall Number of Baseline Participants 20 20 40
Hide Baseline Analysis Population Description
[Not Specified]
Age, Categorical  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 20 participants 20 participants 40 participants
<=18 years
20
 100.0%
20
 100.0%
40
 100.0%
Between 18 and 65 years
0
   0.0%
0
   0.0%
0
   0.0%
>=65 years
0
   0.0%
0
   0.0%
0
   0.0%
Age, Continuous  
Mean (Standard Deviation)
Unit of measure:  Years
Number Analyzed 20 participants 20 participants 40 participants
15.1  (1.2) 15.3  (0.9) 15.1  (1.0)
Sex: Female, Male  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 20 participants 20 participants 40 participants
Female
20
 100.0%
20
 100.0%
40
 100.0%
Male
0
   0.0%
0
   0.0%
0
   0.0%
Race (NIH/OMB)  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 20 participants 20 participants 40 participants
American Indian or Alaska Native
0
   0.0%
0
   0.0%
0
   0.0%
Asian
20
 100.0%
20
 100.0%
40
 100.0%
Native Hawaiian or Other Pacific Islander
0
   0.0%
0
   0.0%
0
   0.0%
Black or African American
0
   0.0%
0
   0.0%
0
   0.0%
White
0
   0.0%
0
   0.0%
0
   0.0%
More than one race
0
   0.0%
0
   0.0%
0
   0.0%
Unknown or Not Reported
0
   0.0%
0
   0.0%
0
   0.0%
Region of Enrollment  
Measure Type: Number
Unit of measure:  Participants
South Korea Number Analyzed 20 participants 20 participants 40 participants
20 20 40
Arterial stiffness  
Mean (Standard Deviation)
Unit of measure:  M/s
Number Analyzed 20 participants 20 participants 40 participants
8.2  (0.5) 8.2  (1) 8.2  (0.8)
Endothelin-1  
Mean (Standard Deviation)
Unit of measure:  umol/mL
Number Analyzed 20 participants 20 participants 40 participants
0.41  (0.21) 0.37  (0.21) 0.40  (0.21)
Body mass  
Mean (Standard Deviation)
Unit of measure:  Kg
Number Analyzed 20 participants 20 participants 40 participants
68  (8) 69  (9.4) 68.5  (8.7)
Height  
Mean (Standard Deviation)
Unit of measure:  Cm
Number Analyzed 20 participants 20 participants 40 participants
161  (3) 160  (3) 160.5  (3)
Waist circumference  
Mean (Standard Deviation)
Unit of measure:  Cm
Number Analyzed 20 participants 20 participants 40 participants
85.3  (4) 86.4  (4) 85.9  (4)
Body Fat  
Mean (Standard Deviation)
Unit of measure:  Percent
Number Analyzed 20 participants 20 participants 40 participants
32.7  (3.2) 33.8  (3.6) 33.3  (3.4)
Lean Body Mass  
Mean (Standard Deviation)
Unit of measure:  Kg
Number Analyzed 20 participants 20 participants 40 participants
43.7  (4.2) 44.9  (4.5) 44.3  (4.3)
Nitrate/Nitrite Levels  
Mean (Standard Deviation)
Unit of measure:  Umol
Number Analyzed 20 participants 20 participants 40 participants
53.3  (4.3) 54.5  (5.1) 53.9  (4.7)
C-reactive protein  
Mean (Standard Deviation)
Unit of measure:  mg/L
Number Analyzed 20 participants 20 participants 40 participants
0.5  (0.3) 0.5  (0.4) 0.5  (0.4)
Systolic blood pressure  
Mean (Standard Deviation)
Unit of measure:  mmHg
Number Analyzed 20 participants 20 participants 40 participants
126  (4.2) 126  (3.3) 126  (3.8)
Diastolic Blood Pressure  
Mean (Standard Deviation)
Unit of measure:  mmHg
Number Analyzed 20 participants 20 participants 40 participants
82  (2) 82  (0.4) 82  (1.3)
1.Primary Outcome
Title Arterial Stiffness
Hide Description Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: m/s
8.1  (0.2) 7.4  (0.2)
2.Primary Outcome
Title Endothelin-1
Hide Description Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: umol/mL
0.4  (0.31) 0.38  (0.33)
3.Primary Outcome
Title Body Mass
Hide Description Body mass was measured to nearest 0.1 kg.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: kilograms (kg)
70  (8.9) 66  (7.3)
4.Primary Outcome
Title Height
Hide Description Height was measured to nearest 1 cm.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: cm
162  (4) 161  (3)
5.Primary Outcome
Title Waist Circumference
Hide Description Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: cm
84.4  (5.2) 80.1  (4.8)
6.Primary Outcome
Title Body Fat
Hide Description Percent body fat (%) was determined using a bioelectrical impedance-meter.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: percent
33.5  (3.7) 30.2  (3.1)
7.Primary Outcome
Title Lean Body Mass
Hide Description Lean body mass (kg) was determined using a bioelectrical impedance-meter.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: kilograms (kg)
42.8  (6.5) 45.9  (6.7)
8.Primary Outcome
Title Nitrate/Nitrite Levels
Hide Description Nitrate and nitrite levels were assayed using a Griess assay kit.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: umol
53.5  (5.2) 57.2  (5.2)
9.Primary Outcome
Title C-reactive Protein
Hide Description C-reactive protein was assessed using an enzyme immunoassay assay kit
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: mg/L
0.7  (0.4) 0.2  (0.1)
10.Primary Outcome
Title Systolic Blood Pressure
Hide Description Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: mmHg
127  (5.3) 120  (2.1)
11.Primary Outcome
Title Diastolic Blood Pressure
Hide Description [Not Specified]
Time Frame 12 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description:
No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

Overall Number of Participants Analyzed 20 20
Mean (Standard Deviation)
Unit of Measure: mmHg
84  (1.9) 80  (2)
Time Frame 6 months
Adverse Event Reporting Description [Not Specified]
 
Arm/Group Title Control Group Jump Rope Exercise Intervention
Hide Arm/Group Description No exercise intervention

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Jump rope exercise intervention: 12-week jump rope exercise program

All-Cause Mortality
Control Group Jump Rope Exercise Intervention
Affected / at Risk (%) Affected / at Risk (%)
Total   0/20 (0.00%)   0/20 (0.00%) 
Show Serious Adverse Events Hide Serious Adverse Events
Control Group Jump Rope Exercise Intervention
Affected / at Risk (%) Affected / at Risk (%)
Total   0/20 (0.00%)   0/20 (0.00%) 
Show Other (Not Including Serious) Adverse Events Hide Other (Not Including Serious) Adverse Events
Frequency Threshold for Reporting Other Adverse Events 0%
Control Group Jump Rope Exercise Intervention
Affected / at Risk (%) Affected / at Risk (%)
Total   0/20 (0.00%)   0/20 (0.00%) 
Certain Agreements
All Principal Investigators ARE employed by the organization sponsoring the study.
Results Point of Contact
Layout table for Results Point of Contact information
Name/Title: Dr. Song-Young Park
Organization: The University of Nebraska at Omaha
Phone: 402-554-3374
EMail: song-youngpark@unomaha.edu
Layout table for additonal information
Responsible Party: Songyoung Park, Pusan National University
ClinicalTrials.gov Identifier: NCT03534427     History of Changes
Other Study ID Numbers: PusanNU1
First Submitted: May 11, 2018
First Posted: May 23, 2018
Results First Submitted: March 27, 2019
Results First Posted: August 14, 2019
Last Update Posted: August 14, 2019