European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

• ClinicalTrials.gov Identifier: NCT04366921
• Recruitment Status: Recruiting
• First Posted: April 29, 2020
• Last Update Posted: September 5, 2021
• Sponsor: Maastricht University Medical Center
• Collaborators: European chapter of the Extracorporeal Life Support Organization; Erasmus Medical Center; Leiden University Medical Center; UMC Utrecht; IRCCS Azienda Ospedaliero-Universitaria di Bologna; Papa Giovanni XXIII Hospital; Niguarda Hospital; Ospedale San Donato; Ospedale S. Giovanni Bosco; IRCCS Policlinico S. Matteo; The Mediterranean Institute for Transplantation and Advanced Specialized Therapies; Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia; Ospedale dell'Angelo, Venezia-Mestre; University Hospital, Udine, Italy; San Gerardo Hospital; Ospedali Riuniti Ancona; San Camillo Hospital, Rome; San Giorgio Clinic; GVM Care & Research; San Raffaele University Hospital, Italy; Ospedale San Bortolo di Vicenza; Klinik Hirslanden, Zurich; University of Zurich; Cardiocentro Ticino; Vilnius University Hospital Santaros Klinikos; Universitätsklinikum Düsseldorf; Klinikum Nürnberg; Hannover Medical School; Heart Center Leipzig - University Hospital; University Hospital Regensburg; University Hospital, Essen; German Heart Center; University Hospital, Aachen; University Heart Center Freiburg - Bad Krozingen; Klinikum Kassel; General University Hospital, Prague; Universitaire Ziekenhuizen KU Leuven; Onze Lieve Vrouwziekenhuis Aalst; Erasme University Hospital; University Hospital, Antwerp; Hôpital Civil Marie Curie de Charleroi; University Hospital, Ghent; Centre Hospitalier Universitaire Saint Pierre; Hospital Vall d'Hebron; Hospital Universitario Ramon y Cajal; Hospital Miguel Servet; Henri Mondor University Hospital; Hospices Civils de Lyon; Pitié-Salpêtrière Hospital; Rennes University Hospital; Guy's and St Thomas' NHS Foundation Trust; Karolinska University Hospital; Hospital Sao Joao; Medical University of Warsaw; Universitätskliniken Innsbruck; Medical University of Vienna; University Hospital, Alexandroupolis; Novosibirsk City Hospital #2; City Clinical Hospital No. 67, Moscow, Russia; City Hospital No 40, Saint Petersburg, Russia; Krasnodar Regional Hospital no 1; Kemerovo Regional Clinical Cardiological Center named after academician L.S. Barbarash; City Hospital No 41, Ekaterinburg, Russia; G. Pasquinucci Heart Hospital, Massa; Charles University, Czech Republic; University Hospital, Bordeaux; Bambino Gesù Hospital and Research Institute; Policlinico Hospital Milan; Gaslini Children's Hospital; Children's Medical Hospital, University of Essen, Essen, Germany; University Hospital, Geneva; Newcastle-upon-Tyne Hospitals NHS Trust; Paediatric Intensive Care Glasgow; Paris South University Hospitals; University of Groningen; Great Ormond Street Hospital for Children NHS Foundation Trust; Hospital Sant Joan de Deu; Heim Pal Children's Hospital; University Hospital, Montpellier; Royal Brompton & Harefield NHS Foundation Trust; Lund University Hospital; Landesklinikum Sankt Polten; Chelyabinsk Regional Clinical Hospital; ECMO Centers Israel; Copenhagen University Hospital at Herlev; Ospedale M. Bufalini Cesena; A.O.U. Città della Salute e della Scienza - Molinette Hospital; Mauriziano Umberto I Hospital; University of Bern; University Hospital, Basel, Switzerland; University of Lausanne Hospitals; University Hospital Tuebingen; Universitätsklinikum Köln; Chirec; Universitair Ziekenhuis Brussel; Centre Hospitalier Universitaire de Liege; La Louvière Hopital; Leicester Royal Infirmary NHS Trust
• Information provided by (Responsible Party): Maastricht University Medical Center

No Study Results Posted on ClinicalTrials.gov for this Study

• Recruitment Status: Recruiting
• Estimated Primary Completion Date: April 2022
• Estimated Study Completion Date: April 2022

Publications:

Bolotin S, Pebody R, White PJ, McMenamin J, Perera L, Nguyen-Van-Tam JS, Barlow T, Watson JM; UK Severe Influenza Surveillance System (USISS) Steering Group. A new sentinel surveillance system for severe influenza in England shows a shift in age distribution of hospitalised cases in the post-pandemic period. PLoS One. 2012;7(1):e30279. doi: 10.1371/journal.pone.0030279. Epub 2012 Jan 23.

Dawood FS, Iuliano AD, Reed C, Meltzer MI, Shay DK, Cheng PY, Bandaranayake D, Breiman RF, Brooks WA, Buchy P, Feikin DR, Fowler KB, Gordon A, Hien NT, Horby P, Huang QS, Katz MA, Krishnan A, Lal R, Montgomery JM, Molbak K, Pebody R, Presanis AM, Razuri H, Steens A, Tinoco YO, Wallinga J, Yu H, Vong S, Bresee J, Widdowson MA. Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study. Lancet Infect Dis. 2012 Sep;12(9):687-95. doi: 10.1016/S1473-3099(12)70121-4. Epub 2012 Jun 26. Erratum In: Lancet Infect Dis. 2012 Sep;12(9):655.

Simonsen L, Spreeuwenberg P, Lustig R, Taylor RJ, Fleming DM, Kroneman M, Van Kerkhove MD, Mounts AW, Paget WJ; GLaMOR Collaborating Teams. Global mortality estimates for the 2009 Influenza Pandemic from the GLaMOR project: a modeling study. PLoS Med. 2013 Nov;10(11):e1001558. doi: 10.1371/journal.pmed.1001558. Epub 2013 Nov 26.

Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.

Drosten C, Gunther S, Preiser W, van der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A, Burguiere AM, Cinatl J, Eickmann M, Escriou N, Grywna K, Kramme S, Manuguerra JC, Muller S, Rickerts V, Sturmer M, Vieth S, Klenk HD, Osterhaus AD, Schmitz H, Doerr HW. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med. 2003 May 15;348(20):1967-76. doi: 10.1056/NEJMoa030747. Epub 2003 Apr 10.

Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, Tong S, Urbani C, Comer JA, Lim W, Rollin PE, Dowell SF, Ling AE, Humphrey CD, Shieh WJ, Guarner J, Paddock CD, Rota P, Fields B, DeRisi J, Yang JY, Cox N, Hughes JM, LeDuc JW, Bellini WJ, Anderson LJ; SARS Working Group. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003 May 15;348(20):1953-66. doi: 10.1056/NEJMoa030781. Epub 2003 Apr 10.

Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012 Nov 8;367(19):1814-20. doi: 10.1056/NEJMoa1211721. Epub 2012 Oct 17. Erratum In: N Engl J Med. 2013 Jul 25;369(4):394.

de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes L, Fouchier RA, Galiano M, Gorbalenya AE, Memish ZA, Perlman S, Poon LL, Snijder EJ, Stephens GM, Woo PC, Zaki AM, Zambon M, Ziebuhr J. Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol. 2013 Jul;87(14):7790-2. doi: 10.1128/JVI.01244-13. Epub 2013 May 15. No abstract available.

Spina S, Marrazzo F, Migliari M, Stucchi R, Sforza A, Fumagalli R. The response of Milan's Emergency Medical System to the COVID-19 outbreak in Italy. Lancet. 2020 Mar 14;395(10227):e49-e50. doi: 10.1016/S0140-6736(20)30493-1. Epub 2020 Feb 28. No abstract available.

Ebrahim SH, Memish ZA. COVID-19: preparing for superspreader potential among Umrah pilgrims to Saudi Arabia. Lancet. 2020 Mar 14;395(10227):e48. doi: 10.1016/S0140-6736(20)30466-9. Epub 2020 Feb 27. No abstract available.

Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, Spitters C, Ericson K, Wilkerson S, Tural A, Diaz G, Cohn A, Fox L, Patel A, Gerber SI, Kim L, Tong S, Lu X, Lindstrom S, Pallansch MA, Weldon WC, Biggs HM, Uyeki TM, Pillai SK; Washington State 2019-nCoV Case Investigation Team. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med. 2020 Mar 5;382(10):929-936. doi: 10.1056/NEJMoa2001191. Epub 2020 Jan 31.

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24. Erratum In: Lancet. 2020 Jan 30;:

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585. Erratum In: JAMA. 2021 Mar 16;325(11):1113.

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Lorusso R, De Piero ME, Mariani S, Di Mauro M, Folliguet T, Taccone FS, Camporota L, Swol J, Wiedemann D, Belliato M, Broman LM, Vuylsteke A, Kassif Y, Scandroglio AM, Fanelli V, Gaudard P, Ledot S, Barker J, Boeken U, Maier S, Kersten A, Meyns B, Pozzi M, Pedersen FM, Schellongowski P, Kirali K, Barrett N, Riera J, Mueller T, Belohlavek J; EuroECMO-COVID Study Group. In-hospital and 6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study. Lancet Respir Med. 2023 Feb;11(2):151-162. doi: 10.1016/S2213-2600(22)00403-9. Epub 2022 Nov 16.